II. _State of the Cartilaginous System in the after ages._

As we advance in age, the cartilages become harder, stronger, and less

elastic. The gelatine that nourishes them has a peculiar character;

for we know that the glue made from young animals differs essentially

from that made from old ones. The cooks know very well the difference

there is between the foot of a calf and that of an ox for jelly. This

difference in the substance which essentially composes the cartilages,

and which is undoubtedly their nutritive matter, evidently indicates

that it does not always remain in these organs, but that it is

constantly exhaled and absorbed there, as the phosphate of lime is in

the bones, the fibrin in the muscles, &c.

In the last years of life, ossification seizes upon all the cartilages;

but it begins in an opposite manner in those of the cavities and in

those of the articulations. In the first it is by the centre, in the

second it is by their surface which corresponds to the bone, that it

commences; in general it is much slower in the latter, and among these,

it is slower in the moveable articulations than in the immoveable.

The cartilages of the larynx and the ribs are osseous in their centre

at the age of thirty-six or forty years, and even before; they

afterwards become more and more so; it is this that renders the section

of the thyroid cartilage very difficult in the last periods of life.

In the great number of operations that I have shown to students,

I have satisfied myself, that after sixty years, the bistoury of

ordinary temper is almost always insufficient to make this section;

it requires something much stronger. It is the ossification of the

costal cartilages, which renders old people unable to make those great

efforts of inspiration so common to young ones; with them the diaphragm

especially acts. I attribute also to this early ossification of the

cartilages of the cavities, an ossification which always accompanies

the development of the vascular system, the greater frequency of caries

in this sort of cartilages than in all the others. I know not why

in the larynx the arytenoid cartilages are the most exposed to this

affection; but in the opening of dead bodies, it is a constant fact,

all the cases of laryngeal phthisis with caries, that I have observed

in the dead body, have shown me this.

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