III. _Preternatural Development of the Cartilaginous System._

The cartilaginous system, like the osseous, is often developed

in organs to which it is naturally a stranger. But there is this

difference, that this phenomenon appears to be an effect of age

in the first, whereas in the second it is always the effect of

disease. Nothing is more common than to find cartilaginous balls in

scirrhous, cancerous tumours, &c.; in the middle of those frequent

morbid productions, in which the parts have an appearance like

lard, in the lungs, liver, &c. when enlarged. I do not know why the

peculiar membrane of the spleen has a great tendency to be encrusted

with gelatine; it is perhaps of all the organs, that in which the

preternatural cartilages are the most frequent. It is usually by

irregular scales that the cartilaginous development appears; sometimes

it attacks the whole membrane, which then presents a convex surface

analogous to the convex surfaces of the moveable articulations, which

the peritoneum covers, as these are covered by the synovial membrane.

Can the spleen, when thus cartilaginous externally, yield to the

changes of size that it often undergoes? I know not.

We know that there are often moveable and loose cartilaginous

substances in the articulations. Do they arise from the ossification

of a portion of the synovial membrane? I presume they do; for we

frequently see them hold to the cartilage by membranous expansions. I

have seen in a dead body, within the last year, the portion of synovial

membrane that goes from the fatty substance behind the patella, to the

depression that separates the condyles of the femur, almost wholly

cartilaginous. If during life it had been detached by the effect of

the motions, it would have formed one of these moveable and loose

cartilages. Besides, as I know but this fact which seems peculiarly

applicable to this point, I can only offer conjectures, especially as

we know that the synovial and serous membranes are of the same nature,

and yet these last hardly ever become cartilaginous.

Moreover these productions follow entirely the ordinary progress

of ossification. At first cartilaginous and without blood vessels,

they soon acquire a red centre, then osseous, which extends from

the centre to the circumference, and which sometimes terminates by

seizing upon the whole cartilage; so that they are real bones. This

last circumstance is however very rare. The state in which we most

commonly find these productions, is that in which they are osseous in

the middle, and cartilaginous at the circumference. I found one of them

in the articulation of the pisiform bone, of the size of the head of a

great pin, and which, in its whole thickness was harder than ivory.

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