The suppression as well as the absence of menstruation may be caused by

atresia of the passages, this form differing from the congenital only

etiologically, and in the fact that the flow has been once established.

The acquired atresiæ are mostly the result of violent inflammations or

traumatic influences. The vulva and vagina, or either, may be closed

from sloughing after difficult labors or gangrene following the septic

fevers. Occlusion of the cervix uteri may follow labor or amputation of

the part, but a far more frequent cause is the application of severe

caustics, happily less frequent now than formerly. Lawson Tait says he

has never met with atresia of this part from any other cause.

The mode of diagnosis has already been given, and in regard to

symptomatology there is only to be noted the statement of Bernutz, that

there is far greater intolerance of retention from acquired than from

congenital atresia.

Atrophy of the uterus is a normal process after the menopause, but it

sometimes occurs much earlier in life, and then causes scanty and

irregular menstruation or amenorrhoea. Attention was first called to

this condition by Simpson as a process sometimes following parturition

under the name of super-involution. Several labors in rapid succession

have been stated to be a cause, but Simpson and Courty both give a case

after a single birth. Uterine atrophy may also result from the pressure

of tumors, and it has been observed in paraplegias the result of

defective innervation.

The deranged menstruation is the one prominent symptom of this

condition, and a diagnosis is to be made by exploration. The cervix is

found small and the body light when lifted on the finger. Bimanual

examination and the introduction of the sound will reveal the true

condition of the organ. The latter process should be cautiously

conducted on account of a frequent change of texture in the uterine

walls which allows the instrument to pass through them with the use of

but very little force.

Amenorrhoea is physiological during nursing and pregnancy. The former

needs no attention, the latter only in regard to diagnosis. A sudden

cessation of menstruation, the patient presenting all the appearances

of good health, should immediately excite suspicion as to the nature of

the cause. It needs but little experience to distinguish and manage

these cases in the lower social ranks. The case is different, however,

in a family of good position, with an anxious mother urgent for active

measures, where no suspicions will be tolerated and the imputation of

possible pregnancy be warmly resented. Time is here the sure ally of

the physician, and an examination should be deferred until such a

period {187} has been reached that pregnancy can be positively

negatived or determined.

The influence of acute diseases in suppressing menstruation is not

marked. During convalescence from them the flow frequently ceases from

general debility. All chronic diseases depressing and exhausting in

nature cause suppression, as albuminuria, cirrhosis, and cancer.

Tuberculosis is as fruitful in interrupting the return as in preventing

the appearance of the flow, and suppression from this cause is very

frequent. Under impaired nutrition and depressed powers vital force is

engaged wholly in maintaining existence; there is none for any function

relating to the propagation of the species. In this class the

disappearance is gradual; the flow becomes scanty and irregular in

recurrence, and finally ceases. This form of amenorrhoea differs in no

material point from the similar class already considered; it is but a

symptom of disease of some vital organ or of some general abnormal

condition.

Suppression from psychical influences is not at all uncommon. Fright,

grief, bad news, sudden or prolonged anxiety, frequently cause this

disturbance of function. The mental impression need not be very

profound. Amenorrhoea is a common event with girls who go away from

home to boarding-school. In these cases it is not probable that there

is any pathological condition of the sexual organs; a change in their

innervation is a phrase which will best serve to explain the origin of

the derangement or to express our ignorance. The diagnosis of this form

may be a matter of deep interest when it occurs directly after

marriage, as it not infrequently does, and gives ground for the belief

that pregnancy has occurred. Still more important is it when the

suppression follows illicit intercourse, the fear of pregnancy then

exerting a powerful emotional influence. Some cases are on record, and

the writer has met with two: in both the function resumed its course

after a time without remedies.

Exposure to storm, getting the feet wet, and the sudden application of

cold to the genitals frequently cause suppression. All the conditions,

however, are not well understood. The bathing- and fishing-women of

Europe are said to ply their vocation without reference to

menstruation, and to suffer no inconvenience. In these cases the

increased flow of blood to the pelvic organs oversteps the narrow line

which separates physiological from pathological congestion, and may

even pass on to inflammation.

The SYMPTOMS are well marked--at first, local, as severe backache,

increased heat and pressure in the pelvic region, discomfort passing on

to pain, even uterine colic. If the impression be severe enough to

affect the general system, there will be febrile action more or less

intense, and various nervous symptoms, spasmodic or convulsive.

The therapeutics of amenorrhoea must be directed in accordance with the

conditions which cause it. But the strictly scientific method cannot be

followed at the outset. This method presupposes a direct examination of

the organs as the first step. For obvious reasons this must be deferred

until special symptoms show its necessity. For treatment the cases may

be classified, in some instances according to the schedule, but more

frequently according to the cause or leading features, and very

generally without reference to whether there is absence merely or

suppression of the function.

In amenorrhoea from atresia the measures of relief will be purely {188}

surgical; the treatment, therefore, does not fall within the scope of

this article.

The physician is frequently consulted in cases where menstruation has

occurred once or twice, perhaps at long intervals, and not appearing

regularly the fears of friends are excited. This is the normal course

of establishment in a large proportion of cases. Time and assurance and

regimen are alone needed, provided there is no evidence of deteriorated

health. Absence of the function alone does not demand treatment--a fact

which should be kept steadily in mind.

In a still larger class of cases the amenorrhoea depends upon, and is

the direct result of, some pronounced cachectic condition, as

chlorosis, scrofula, or a more or less active tubercular disease of the

lungs. The treatment of this class resolves itself into that of the

disease causing the derangement, and the reader is referred to the

articles on the corresponding subjects.

The cases requiring more direct consideration therapeutically are those

closely allied to the preceding, in which delay in appearance depends

upon want of development of the body or general feebleness of

constitution, or those in which absence follows and continues unduly

after some severe disease. In all these cases the treatment is to be

indirect rather than direct. The absent function is to be restored by

improving nutrition, by increasing bodily vigor, and by using every

means to establish the general health on a firm basis. Measures for

this purpose should be addressed to every particular of the habits,

occupation, and surroundings of the patient. They do not differ from

those of a general tonic course, but in some particulars a special

influence may be exerted upon the function at fault. The clothing

should be warm, especially about the pelvis and lower extremities, due

care of the feet being impressed in proportion to the universal neglect

shown by girls and women in regard to these important parts of the

person. The diet should be of plain, wholesome, substantial food, and

in many cases one of the lighter wines may be added to the principal

meal of the day with decided advantage. Gymnastics may be prescribed,

but outdoor life should be urged, with horseback riding as the very

best mode of exercise for promoting the flow. A change of air and scene

exerts a well-known and powerful influence in improving nutrition and

modifying vital actions. It should be rather from the city to the

country for these cases. Special advantages may be derived from a

residence at the seaside on account of the beneficial effects of

surf-bathing. A scientifically-conducted hydropathic establishment is

very desirable for its regular hours, well-ordered diet, and treatment

by baths and douches. Or a watering-place may be preferred where a

chalybeate water may exert a special influence in addition to those of

moderate indulgence in the gayety and amusement of such a place.

Inquiry as to school-life and educational work should never be omitted.

The general mode of education of girls is faulty in the extreme. No

attention is paid to the great change of puberty, which amounts to a

revolution in the economy, and instead of aiding the vital forces drawn

upon for effecting this change, they are still further depressed by

sedentary life in close rooms or strongly urged in another direction.

No two leading organs of the body can be pushed in development at the

same time with impunity. There is no exception here: either the brain

and nervous {189} system or the sexual organs will suffer. In this

direction is often found a potent cause of all the forms of uterine

derangement--a fact which cannot have escaped the observation of every

physician. The writer has always urged an entire break in the

school-life of girls of at least one year's duration at the time when

signs of puberty begin to manifest themselves; and this period is too

short rather than too long.

Tonics should supplement these regiminal measures. They may be hæmatic,

stomachic, and nervous--either or all. There is a chain of diseased

actions, and it may be attacked at any of its links. Iron stands at the

head of the list. It is not only an hæmatic tonic, and in proper

conditions a promoter of digestion, but decidedly promotes pelvic

congestion, and has therefore an emmenagogue action. The forms at

command are so numerous as to meet the requirements of any case or to

satisfy any fancy. The standard preparations, as a rule, deserve the

preference over more modern ones, in which efficacy is often sacrificed

to elegance. Among the best are those which contain the remedy in a

nascent state, as the compound mixture or the compound pills of iron of

the Pharmacopoeia. Dialyzed iron, the tincture of the chloride, and the

pyrophosphate are reliable, while the addition of manganese, as in the

syrup of the iodide of iron and manganese, is believed by some to

increase the efficacy. With iron may be combined nux vomica or

strychnia and quinia. In large sections of our country malaria is a

constantly-acting depressant of vital force, and the latter medicine

may be given for a time with a free hand, and may be followed by or

combined with arsenic to great advantage.

Constipation is almost universally present in women. It deserves

especial consideration in treating all disorders of the sexual organs.

When attention to habits and appropriate laxative food, as fruits,

oatmeal, Indian meal, cracked wheat, and salads, do not suffice, resort

must be had to enemata or drugs. Aloes has always had a reputation of

special virtue in amenorrhoea which is doubtless well founded. In pill

form it may be combined with any or all the other medicines. Pills of

aloin, one-fifth or one-third of a grain, have the advantage of very

small bulk.

Before considering more direct measures for establishing menstruation

it may be well to recall to mind the two elements of the

function--ovulation and the uterine flow. The first, the prime factor,

we can not influence by any medicines nor by any mode of treatment

except, perhaps, by electricity. Observation of animals shows that mere

proximity of the male influences it plainly, but this only indicates a

line along which we cannot prescribe. An opinion may, however, be asked

in regard to the propriety or advisability of marriage for a woman who

has never menstruated. In such case no advice should be given until

after a thorough local examination, and its tenor will then be in

accord with the condition of the organs. With such atresia or absence

of organs as not to permit sexual intercourse marriage should be

positively negatived. In such cases as those of partially-developed or

absent uterus the facts should be laid before the parties interested

and the decision referred to them. In the former class of cases some

hopes of improvement may be entertained.

The second factor of menstruation, the flow, we can influence by such

measures as cause a more or less intense pelvic congestion. The ovaries

sharing in this congestion, it is not impossible that ovulation is in

some {190} degree also promoted, but it can be only to a minor degree

and when the ovaries are in a favorable condition. The uterus is the

principal organ to be affected, and to it the most of these measures

are addressed.

Direct treatment for the establishment of menstruation should be first

of a character rather to solicit than to force the flow. These measures

act best where, the general health having been restored, the flow does

not appear, but the premonitory symptoms are present. Rest in bed,

warmth to the pelvic region by poultices or other means, and hot

drinks, are to be prescribed; among the latter infusions of pennyroyal,

some of the mints, tansy, and cotton-root have a high domestic

reputation and should be preferred. Hot pediluvia or hot sitz-baths,

prolonged to twenty or thirty minutes, may be taken at bedtime. These

may be rendered sufficiently stimulating to irritate the skin by the

addition of mustard. More active measures are stimulating enemata and

vaginal injections--for the former ten grains of aloes in mucilage, and

for the latter liquor ammonia in milk, fluidrachm j-pint j, gradually

increasing the strength to production of slight leucorrhoea. Both these

have the endorsement of high authority.

Such measures should be used or plied more assiduously about the

period, when that is known. During the interval a tonic course is

almost always required, and a powerful local influence can be exerted

by cold sitz-baths of brief duration, say one or two minutes, once

daily, followed by vigorous rubbing with a coarse towel or a

flesh-brush.

There are a few drugs known as emmenagogues from the reputation they

have of promoting the menstrual flow. They all are powerful stimulants

or irritants, and as they are also nearly all abortifacients, their

reputation is probably well founded. Modern physiology, by exploding

the doctrine of peccant humors to be carried off by menstruation, and

by establishing the doctrine of ovulation, has greatly diminished their

importance, while the varied conditions and causes of amenorrhoea

already given show at a glance how restricted is the field for their

administration. To give them when the anatomical conditions are unknown

is blind work; to force a function relating to reproduction when the

general system is struggling for existence is folly; and to goad

diseased organs with special stimulants is certain to do injury. Now

and then, however, special stimulants of this class and of the class

next to be considered are required. There are some cases which fail to

respond to the measures already detailed; there are others, generally

recognized by writers, when menstruation is absent without any

deterioration of health, known as cases of sexual atony or torpor; and

others in which the flow fails or disappears earlier than the usual

age. In these latter atrophy of the ovaries may be suspected, but

cannot be verified during life, and treatment should be faithfully

continued so long as there is reasonable probability of success. One

case occurred in the experience of the writer in which the menses

appeared occasionally during two years, each time apparently brought on

by special stimulants, but ceased at thirty-two, the general health

remaining excellent.

The principal emmenagogue drugs heretofore relied on, besides iron, are

saffron, apiol, rue, and savin. The first, from impurity and

costliness, is rarely prescribed, yet Trousseau says it is a fact of

public notoriety that women engaged in picking saffron suffer from

frequent attacks of uterine hemorrhage. Apiol may be given in capsules

in doses of five or six {191} drops twice daily for a week before the

expected flow, or fifteen drops may be administered in the course of

the few hours immediately preceding. The oils of savin and rue are

generally prescribed in doses of minim ij-v, three times daily. Ergot

and iodine figure sometimes as emmenagogues. The efficacy of the former

is denied by very high authority. The latter was esteemed very highly

by Trousseau. Its influence upon the scrofulous constitution may

possibly explain its action in promoting menstruation.

The permanganate of potassium is a recent addition to emmenagogues, and

the testimony in its favor is already sufficient to make it probable

that it is the most efficient of the list. The indications for its use

are want of action or atony of the organs. It should be administered

during a few days or a week preceding the time for menstruation, in

doses of from two to four grains three times daily; or two grains three

times daily may be administered during the whole month. The union of

its elements is but feeble, so that in pills as ordinarily made it

would be very likely to undergo decomposition, while in solution it is

unpleasant. Compressed tablets of the pure drug are now placed at

command of the profession, and are an unexceptionable form for

administration. The best time for taking the medicine is toward the

close of the digestive process, and each dose should be followed by

drinking at least a wineglassful of water. Pain in the stomach has been

sometimes observed even when every precaution has been taken. The

liability of the remedy to decomposition and its irritating powers are

objections to it, but the testimony in favor of its power to bring on

or promote the menstrual flow is at present very strong.

More decided measures of local stimulation than those already given may

be resorted to, and are far more reliable than drugs. They are--tents,

cupping the uterus, and electricity. A sea-tangle or tupelo tent may be

kept in the uterus over night just previous to the time of the flow. In

cases where stimulation rather than dilatation is needed a tent of

slippery-elm bark may be used. Thomas recommends a rubber exhauster for

cupping the cervix uteri. Simpson fashioned one for acting on the

lining membrane of the body. These measures are most likely to be

efficacious just before an expected period.

Electricity is the most reliable emmenagogue, and has such an amount of

testimony in its favor as not to permit a doubt as to its value. It is

the only direct uterine or menstrual stimulant except permanganate of

potassium. Statical electricity is now but little used, although

Golding-Bird published striking instances of its efficacy in

amenorrhoea at an early day in its therapeutic history. Faradization is

now most frequently resorted to. One pole is to be applied to the

sacrum and the other above the pubes or over either ovary. The internal

application of the current is much more powerful as well as less

painful. It is administered by applying a cup-shaped electrode to the

cervix, or by introducing an insulated sound into the uterus, the other

electrode being external as before. The séances should be repeated

every second or third day, and should be more frequent just before the

periods when their time is known. Beard and Rockwell insist that

general electrization should be administered at the same time, and Mann

passes the constant current through the organs during the intervals and

the faradic at the periods. Simpson originated {192} a galvanic

intra-uterine pessary, which Thomas has modified. It is doubtful

whether the feeble current generated by these instruments produces any

effect, or whether they act simply as mechanical irritants. When they

are used, it should be borne in mind that there is eminent and high

authority against the use of intra-uterine pessaries of any kind, and

that all agree that a patient to whom one is applied should be kept

under careful observation.

It must be stated that good results have been obtained with this class

of local remedies in cases which would seem extremely unpromising--even

in those in which amenorrhoea depends upon partially-developed organs.

There is most positive testimony of the highest character as to good

effects obtained in increasing development and promoting the flow.

Cases of acute suppression are to be treated by rest in bed, warmth

locally by baths and applications, and hot drinks, as already detailed.

Steaming the lower part of the body by placing the patient over the

vapor arising from aromatic herbs upon which boiling water has been

poured is a remedy which dates back to Hippocrates. Early in the case a

drink of spirituous liquor, taken hot, is often efficacious. If,

however, there is febrile action, diaphoretics should be administered,

such as the liquor ammonii acetatis with spirits of nitrous ether, and

aconite if required. Dry or wet cupping may be used if there is

evidence of intense uterine congestion. Should internal metritis or

inflammation of some pelvic organ result from acute suppression, the

treatment will be that for the disease thus caused. If efforts to

restore the suppressed flow do not prove speedily successful, special

measures should be postponed until the next period, the general health

meantime receiving due attention. At the return of the next period such

of the remedies for amenorrhoea should be administered as may seem best

adapted to the case, considered as to cause, condition of the organs,

or constitution of the patient.

Vicarious menstruation is so closely allied to amenorrhoea as to demand

some consideration here. The term is applied to a sanguineous flow,

recurring at regular intervals, from some organ or part of the body

other than the uterus. This flow has taken place from almost every

organ or part of the body; most frequently, however, it has been from

some mucous membrane, a wound, scar, or some part which by structure is

favorable to the exit of blood. Amenorrhoea is frequently present, and

is sometimes followed by acute suppression. Puech found 11 cases

attended by vaginal atresia congenital, and in 42 others the uterus was

absent or but partially developed. The treatment does not differ from

that of amenorrhoea. While measures are used to restore normal

menstruation, active repression of the abnormal flow should not be

attempted, unless the organ from which it proceeds is one likely to be

injured by its continuance.

Dysmenorrhoea.

Dysmenorrhoea, according to derivation, signifies a monthly flow with

labor or difficulty; its modern synonym is painful menstruation.

In but a very small proportion of women is menstruation painless. Not

only general and local distress attends it, but more or less pain.

{193} When the suffering reaches such a degree as to demand relief, the

case is one of dysmenorrhoea. In such cases the period generally

commences with a more pronounced molimen than ordinary; as it

progresses pain makes its appearance and gradually increases in

severity. Its seat is the pelvic region, the back and loins, and down

the thighs. It may be paroxysmal or continuous; in some cases the flow

is accompanied by expulsive efforts like those of labor. The pain may

last during the whole period, or relax very much, or even cease as soon

as the flow is freely established. In degree it may reach any height,

often causing the severest agony, taxing the powers of endurance to the

utmost, and requiring the most energetic measures for relief.

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