The organs in proximity to the uterus, partaking as they do of the

menstrual congestion, are also markedly affected. There is rectal

tenesmus, and on the part of the bladder frequent micturition and

dysuria. Remote organs are influenced either directly or by sympathy.

The breasts become tumefied and tender. There is flatulence, nausea, or

even vomiting. The nervous system, during normal menstruation in a

state of erethism, responds readily to the painful impressions, and

presents symptoms of the most varied character and degree, amounting

even to general convulsions.

Attacks of severe pain recurring at short intervals cannot but exert a

powerful deleterious influence upon the general health. Digestion is

interfered with, nutrition and sanguification are imperfectly

performed, and there is a continuous chain of deranged function. The

results to the nervous system, indirect and direct, and sometimes also

from the measures of relief resorted to, are most deplorable. From

every point of view this class of cases presents the strongest claims

for relief.

The discharge in dysmenorrhoea varies very widely in amount and

character. It may be so scanty as to border on amenorrhoea or so

profuse as to be menorrhagic. It may be more or less fluid than usual.

The expulsion of clots is a frequent feature, and the size and shape of

these sometimes give indications of value. Like other uterine

derangements, dysmenorrhoea is not a disease per se, but a symptom of

some pathological condition the exact nature of which is to be

ascertained whenever possible. Cases may be classified as follows: I.,

Obstructive or mechanical; II., congestive; III., neuralgic; IV.,

membranous. It cannot be too distinctly kept in view that this

classification, like many others, cannot be rigidly followed. The

dividing-lines are sometimes but faintly drawn by nature; some cases

present the features of more than one class; some by natural progress

pass from one class into another. Based upon leading clinical features,

this classification will assist in the study of the subject, facilitate

diagnosis, and aid in directing therapeutic measures.

Two classes given by some authorities are not included in the above

classification. They are spasmodic and ovarian dysmenorrhoea. If by the

former is implied painful contractions of the uterus during

menstruation, the cases fall into the first class given above, the

obstructive; and if irregular nervous action is implied, they belong to

the third, the neuralgic. The term ovarian has been applied to those

cases in which an abnormal condition of the ovaries exists, such as

inflammation, enlargement, or dislocation. Such conditions are not

easily ascertained during life; if ascertained, the fact throws light

on the etiology of the case; but for {194} treatment the case will

range itself, according to the clinical features it presents, among

those in which the vascular or the neurotic element predominates.

Obstructive or mechanical dysmenorrhoea is that form in which some

impediment exists to the free escape of the menstrual discharge. The

genital canal presents no exception to the general rule that when an

excretory channel is obstructed violent and painful expulsive efforts

are excited.

The causes which give rise to the obstruction are various. Among them

are the following: fibroid tumors of the uterus distorting, and polypi

obstructing, its cavity or neck; stenosis of the cervical canal, either

congenital or acquired, the latter often the result of the injudicious

use of strong caustics; a long and conical cervix; a contracted os,

sometimes so small as to be justly termed the pinhole os; versions and

flexions of the uterus.

The seat of obstruction is almost always uterine, but may be in the

vagina or at its entrance. There is much difference of opinion as to

the relative frequency of occurrence of obstruction at the internal or

external orifice of the cervix.

The pain in this form of dysmenorrhoea generally does not precede the

flow. In character it is sometimes like colic, but its leading feature

is expulsive effort. It occasionally so nearly resembles abortion as to

require care to distinguish between them. It is frequently

intermittent, presenting intervals of complete relief. In severity it

varies widely. In some cases the patient assumes and maintains a

certain position which she has learned affords her some relief. This

indicates with great probability uterine distortion from fibroid tumor.

The writer has met with a marked instance of this kind.

The flow is more irregular in this than in other forms. It is sometimes

extruded drop by drop; more often it appears in gushes, the fluid

accumulating and distending the uterus until expulsive efforts are

excited. Clots are often thrown off under these circumstances in shape

and size corresponding to the cavity of the uterus.

Absence of prodromata, presence of the fluid being necessary to excite

the pain, the intermittent and especially the expulsive character of

the pain, and the kind of clots, indicate the nature of the case. A

certain diagnosis, however, rests alone on physical examination. This

should be by the touch, bimanual and rectal, and the sound. Sometimes

additional aid will be derived from the speculum. By touch the form,

size, shape, and direction of the cervix are ascertained, and its

relations to the body of the uterus. The sound will give evidence as to

the patency and direction of the cervical canal and uterine cavity.

A diagnosis of obstructive dysmenorrhoea should not be rejected because

the patient occasionally passes a period without pain. In the male an

enlarged prostate may for a long time interfere but little with

micturition, and then all at once completely obstruct the flow of

urine. A diagnosis cannot be based alone upon the condition of the

cervical canal as found during the intermenstrual period. Two elements

are to be considered, each of which may, and doubtless often does, play

a part: tumefaction from the congestion attendant on the process, and

spasm. The latter, caused by reflex action excited by irritation in the

body of the uterus, assumes a leading position with those who claim

that obstruction is the {195} sole cause of dysmenorrhoea. That it

plays an active part in many cases cannot be doubted; that it is a

necessary condition of even spasmodic dysmenorrhoea is disproved by the

positive statement of Matthews Duncan, that in some cases he could pass

a sound freely into the uterus during the paroxysms.

A due estimate of the part which a uterine flexion plays in producing

the dysmenorrhoea is important, but very difficult. Theoretically, the

narrowing of the canal at the point of flexion should account for the

symptoms, but experience does not accord with theory. All cases of

flexion are not accompanied by dysmenorrhoea, and when so accompanied

removal of the deformity does not always cure. Siredey in 52

observations found only 22 cases of dysmenorrhoea. Emmet's

carefully-prepared tables show that in nearly 50 per cent. of

anteflexions menstruation is painless. The conditions necessary seem to

be extreme flexion, producing an acute angle. In less-pronounced cases

it is maintained by many that the flexion is an unimportant factor, and

that the dysmenorrhoea depends upon secondary conditions produced by

it, as endometritis and congestion. The problem is difficult, and each

individual case requires careful study. The facts indicate that there

is much in the pathology of this form of disease not yet fully

understood.

Congestive dysmenorrhoea depends upon an advance of the menstrual

congestion beyond the physiological limits. In these cases the patient

generally suffers for a few days before the period from a sense of

fulness, weight, and heat in the back and pelvic region. Pain follows,

is more or less severe, and varies somewhat in character, although

generally dull and heavy. The hypogastric region usually becomes

distended, and is sometimes very tender to the touch over the ovaries,

"especially on the left side, without any reason for the difference

being known." After a longer or shorter duration of these symptoms the

flow appears, and this is often, especially if free, followed by an

amelioration of the pain. In many cases, however, there is no remission

of the suffering upon the discharge occurring. Not infrequently the

general circulation is affected, the face is flushed, the skin hot, and

there is more or less fever.

The flow may vary widely as to quantity. It is often at first and for a

time more profuse than normal. Leucorrhoea frequently precedes and

follows it, persisting during the entire interval. During that time

also the patient suffers much from backache and bearing down, with

difficulty of walking or of remaining on her feet.

Upon examination the vagina is found hot and tumefied, and increased

arterial action is evident to the touch. The uterus is tender,

enlarged, and heavier than usual. In cases associated with or dependent

upon chronic inflammation or areolar hyperplasia the increase of size

of the uterus during menstruation is marked. The sound may be used to

determine the amount of enlargement and also the amount of tenderness.

In cases dependent on endometritis touching the interior of the organ

causes severe pain. Dyspareunia is frequently a symptom in this class

of cases.

The conditions upon which congestive dysmenorrhoea depends are various,

and may be either general or local or both combined. Plethora is rare

in females, and local congestions are much more frequently dependent

upon anæmia, the abnormal condition of the blood favoring them {196}

directly and also indirectly by its effect on the nervous system. In

past times gout and rheumatism were considered to act frequently as the

cause of dysmenorrhoea. They have almost disappeared from view since

the era of direct examination began. Malaria, however, as a possible

cause or a powerful factor should never be overlooked in regions where

it prevails. The sexual instinct plays an important rôle; enforced

abstinence, especially when suddenly brought about, and excess, being

alike effective etiological factors. Young widows and prostitutes are

both subject to this form of disease.

The local causes are numerous. Pelvic inflammations, as cellulitis or

pelvic peritonitis, give rise to the disease. Affections of the uterus

are frequent causes; displacements, as retroversion or prolapsus; and

inflammation, either parenchymatous or of the endometrium. Quite a

moderate grade of inflammation, as found during the interval, may,

under the increased congestion of menstruation, become extreme. Many

cases doubtless depend upon an ovarian influence even when no affection

of these organs can be made out. Scanzoni hazards the theory that the

maturation of Graäfian vesicles lying deeper than usual in the stroma

of the ovary is one cause of this form of dysmenorrhoea.

In neuralgic dysmenorrhoea the neurotic element preponderates. The

nerves play a part corresponding to that of the vessels in the

congestive form. In some cases of this class no organic lesions can be

discovered, and they are then termed idiopathic.

This form of dysmenorrhoea depends upon either a peculiar condition of

the general nervous system or upon hyperæsthesia of the sexual system,

or both combined. Either or both may have been inherited or acquired.

It is frequent in subjects of the hysterical temperament, and in those

presenting that preponderance of the nervous system so often seen as

the result of over-refinement, luxury, habits of idleness, and other

violations of hygienic law. Those subject to it often suffer from

severe headaches, neuralgia, and other nervous affections. It is often

caused by anæmia or chlorosis. Sexual influences, psychical or

physical, and especially those that excite without satisfying, are

sometimes efficient causes. Ovarian influence is often an important

factor; some authorities designate all those cases in which no

anatomical change can be found, ovarian. The prodromata of this form

are very apt to be some of those nervous attacks to which such patients

are liable, as headache or neuralgia, and they may be psychical, as

aberration of temper, undue irritability, or tendency to melancholy. In

character the pain is generally stated to be more acute than in the

other forms. It is subject to great and sudden alternations. In

acuteness and irregularity it often justifies the term spasmodic. From

these characters and from the absence of anatomical change a

differential diagnosis may be made. As in this form the most marked

nervous symptoms are witnessed, so are also the most pronounced

complications on the part of the general nervous system. They are often

hysterical in character, but may be of every kind and degree, even to

general convulsions, and mental aberration is sometimes a complication

or result.

Membranous dysmenorrhoea is characterized by the expulsion at the

menstrual periods of organized membrane, either as a whole or in

pieces. In the former case it is like a cast of the interior surface of

the {197} uterus. The expulsion of this membrane is accompanied by

pain, often of the most severe character. The pain presents well-marked

features; it is markedly expulsive, identical with that of the

obstructive form, closely resembling an abortion, to which the membrane

adds an additional element of similarity. This pain and these expulsive

efforts may continue twelve, eighteen, or twenty-four hours, and then

cease, to be renewed only at the next period.

This form of disease is rare--so rare that observers having a large

field of observation may never meet with over half a dozen cases. In

regard to many points very diverse views are held, and the limits of a

practical work do not permit even a statement of all of them. The

nature of the membrane is one of these points too important to pass

over. When thrown off entire, its internal surface is smooth and marked

by the openings of the utricular glands; its external or uterine face

is rough and villous. It presents the exact shape of the interior of

the uterus, with openings corresponding to the Fallopian tubes and the

os. It is impossible to escape the conviction that this membrane is the

lining membrane of the uterus, thrown off as a whole, instead of by

gradual melting down of its superficial layers, as in normal

menstruation. The microscope sustains this view, and this is the

generally received opinion; yet that the membrane is not always such is

testified by competent observers from observations with the same

instrument. It seems probable that this disputed point will be settled,

as have been so many others in medicine, in favor of both parties.

Siredey suggests the possibility of different kinds of membrane in

these cases, while Barnes boldly states this as a fact.

Various theories have been advanced to account for the formation of the

membrane. An abnormal course of conception, a changed ovarian

influence, a peculiar endometritis, have been from time to time

favorite terms in which to express our ignorance. Only in regard to the

first has unanimity been obtained. That the membrane is always a

product of conception is not now maintained by any respectable

authority. It is a well-established fact of the utmost importance that

such membranes may be expelled when there has never been sexual

intercourse.

The membrane of dysmenorrhoea is to be distinguished from fibrinous

masses, the remains of blood-clots from which the corpuscles have been

squeezed; from mucus coagulated into shreds by astringent injections;

and from the products of membranous vaginitis. Neither of these will

present much difficulty with the aid of the microscope. The case is

very different, however, when the membrane is to be distinguished from

the decidua of an early pregnancy. From a single specimen or a single

attack a diagnosis cannot be made. Thomas gives an instance of

disagreement as to the nature of the same membrane by two of the

highest microscopical authorities. The recurrence of the attacks at the

regular menstrual periods will establish the diagnosis.

The prognosis of dysmenorrhoea varies in the different classes. In the

obstructive form it will depend upon the curability of the lesion upon

which it depends, and the same may be said of the congestive. The

neuralgic cases do not yield readily to treatment, especially when

dependent upon a peculiar and perhaps inherited nervous constitution.

Caution should be exercised, however, in expressing an unfavorable

prognosis. {198} Like all nervous diseases in the female, it is subject

to great mutations without apparent adequate cause, and will sometimes

suddenly disappear in an inexplicable manner.

The membranous form affords still less promise of cure: the

unsatisfactory results of treatment are generally acknowledged.

During an attack of dysmenorrhoea the patient should remain in bed for

the benefit of rest and warmth. In those cases where the flow is not

too free, and especially when relief follows its appearance, active

measures to promote this end may be instituted by hot drinks and hot

fomentations. In married patients a hot sitz-bath, during which the

vaginal syringe is used to douche the uterus, is an efficient measure.

Pain being the prominent symptom, and remedies for its relief being at

hand and reliable, the indication is clear and the treatment can be

briefly stated. In execution, however, it is not a simple problem:

immediate relief is not alone to be considered. If opiates be resorted

to for frequently-recurring pain, a habit will soon be formed that is

no less a calamity than the disease itself. While, therefore, opium and

its preparations are reliable remedies, and in many cases

indispensable, they should be administered as seldom and as sparingly

as possible, and always with an appreciation of possible injurious

consequences. Many cases can be successfully managed with chloral

hydrate, or belladonna, or Indian hemp. When opiates are resorted to,

they should be combined as much as possible with other medicines by

which their effects are modified, and relief afforded with the smallest

possible dose. Thus in cases attended with vascular excitement these

ends may be attained by the union of opium with tartar emetic or

aconite; when there is marked disturbance of the nervous system, it may

be combined with an antispasmodic, as the compound spirit of ether.

Administration by the rectum will produce a local as well as a general

effect, and injections of starch and laudanum or suppositories of opium

and belladonna may be administered. The speediest and most certain

relief is afforded by the hypodermic syringe. Resort to it should,

however, be rigidly controlled; it should be used as a miser uses his

gold, and it need scarcely be added that only very exceptional, if any,

circumstances will ever justify placing the syringe in the hands of

friends or attendants, no matter with what restrictions. Unfortunately,

this is sometimes done, but very rarely without great injury resulting.

During the intervals general treatment should be instituted according

to the indications. All functions at fault are to be regulated. Anæmia

is to be corrected, the debilitating effects of malaria counteracted,

good digestion promoted, and a weakened nervous system strengthened.

These indications are met by tonics in various forms, notably iron and

zinc; by antiperiodics, as quinia and arsenic; by stomachics; and by

the judicious use of wine. There are other remedies quite as useful as

drugs--cold sponging and shower-baths, followed by vigorous rubbing,

general electrization, and, when the patient cannot or will not take

outdoor exercise, massage. Change of scene and air is sometimes

beneficial or even necessary. In many cases of pronounced neuralgic

form, or in which the nervous system has been shattered by the severity

or long duration of the attacks, there can be but little hope of

amelioration without a thorough change of habits and mode of life in

every respect.

The local treatment will be according to the conditions present. In the

{199} obstructive form, polypi are to be removed if present, and in

stenosis the patency of the canal restored. Dilatation may be

accomplished by tents. Should these fail, resort may be had to surgical

measures, as the frequent passage of bougies gradually increasing in

size, forcible dilatation with steel dilators under an anæsthetic, or

by incision. Each of these measures has its advocates, and with all

cures have been effected. Flexions should be corrected as far as

possible by a vaginal pessary. Intra-uterine pessaries more certainly

correct the deformity, but great care should be exercised in their use.

If inflammation be present, uterine or pelvic, they will not be

tolerated or will do positive injury; nor should a patient with any

instrument of this kind ever be allowed to pass out of reach of the

physician unless she can herself remove it.

The treatment of many cases of congestive dysmenorrhoea is very similar

to that of suppressed menstruation from cold--warm drinks, hot

foot- and sitz-baths, fomentations, and douches.

Particular attention should be paid to the bowels, not alone to correct

constipation, but to give full relief to a clogged portal system by

saline purgatives. If there be prolapsus, a pessary should be adapted

so as to keep the uterus up in its place; by this means passive

congestion is much relieved. Bromide of potassium is a reliable remedy

as a corrector of pelvic congestion. In the congestive cases of anæmic

subjects iron will act beneficially; in inflammatory congestion it does

injury. Dysmenorrhoea dependent upon hyperplasia or endometritis should

receive the treatment appropriate to those affections.

In neuralgic dysmenorrhoea the general treatment is far more important

than the local. All those hygienic and therapeutic measures already

detailed should be faithfully persevered with. For the relief of pain

and control of the nervous symptoms enemata of asafoetida are useful.

Chloral may also be administered in the same way or by the stomach,

with camphor, valerian, and the æthers as required. In this form apiol

has been successfully used; the evidence as to its value is clearer

than the explanations of its mode of action. It may be given in

capsules, each containing five grains, one, two, or three daily.

Some local measures often render good service: among them is the

passage of bougies, which sometimes modify the sensitiveness of the

cervical canal, as they do that of the male urethra. The galvanic

current, both continuous and Faradic, has effected cures, but the cases

to which it is best adapted or in which it is most likely to be good

cannot be clearly indicated. A galvanic stem-pessary may be used,

observing due caution. This instrument has been modified and much

improved by Thomas: being made like a string of metallic beads, it is

extremely flexible, and many of its former objectionable features are

removed.

A successful treatment of membranous dysmenorrhoea has not yet been

promulgated. The great difficulty of its cure is admitted by the

highest authorities. Some cases associated with stenosis of the cervix

have been cured by dilatation--a fact which but strengthens the general

principle of correcting all anatomical changes whenever possible.

Strong caustics have been applied to the interior of the uterus with a

view of exerting an alterative influence upon the seat of the disease.

The course seems correct in theory, but in practice it has not proved

fruitful of good results, and treatment in the majority of cases is

limited to palliation.

{200} In regard to marriage in females afflicted with dysmenorrhoea, it

may be stated to be advisable in many cases of the neuralgic form and

in anæmic subjects where the flow is so scanty as to border on

amenorrhoea. In cases of the congestive form, if dependent on

inflammation or on organic lesions, as fibroids, there is very great

probability that the symptoms will be aggravated by this radical change

of mode of life.

Menorrhagia.

A system of practical medicine. By American authors. Vol. 4 · 第 23 / 116 段