DIAGNOSIS.--The educated touch which distinguishes the normal version,

flexion, and movements of the uterus will appreciate the anatomical

differences between pathological and normal anteflexion. The degree of

flexure, the mobility or rigidity, and the size, shape, location, and

consistency of the uterus may be ascertained by conjoined manipulation.

The presence of post-uterine cellulitis is recognized by the pain

caused in dragging the uterus slightly forward and by increased

thickness and tenderness in the region of the utero-sacral ligaments,

which may be felt by vaginal or rectal touch. Anteflexion is

distinguished from a fibroid in the anterior wall of the uterus by the

probe. When the diagnosis of anteflexion is obscured by the presence of

cellulitis, it is usually better to wait for absorption of the exudate

than to subject the patient to needless danger from the probe. Should

it be necessary to pass the probe, the danger is decreased by gentle

manipulation, which is facilitated by Sims's speculum and the

latero-prone position. The common error of mistaking the normal version

and flexion of a prolapsed uterus for pathological {179} version and

flexion has been exposed in a previous paragraph. (See Etiology and

Clinical History of Descent.)

TREATMENT.--If complicating cellulitis or peritonitis exist, in the

relation of either cause or effect to the flexure, its removal becomes

the prime indication, because unless removed it is a positive

contraindication to the more direct treatment of the malposition

itself. Chronic metritis, hyperplasia, hypertrophy, and irremovable

tumors sometimes render cure impossible. Improvement of the general

health, treatment of complications, and palliation then become the only

resources.

The direct treatment of pathological anteflexion has for its object the

straightening of the uterine canal, which is usually accomplished

either by division of the cervix or by dilatation. But before

considering the treatment more specifically, it should be remembered

that surgical treatment of anteflexion in cases of dysmenorrhoea and

sterility is only justifiable when the anteflexion is pathological. To

say that most women who suffer from dysmenorrhoea and sterility have

anteflexion is only saying that in the majority of such cases the

uterus is in its normal position.

The Marion-Sims operation of dividing the cervix is open to two

objections: first, its results are apt to be only temporary, in

consequence of rapid contraction upon healing of the wound; second, it

has frequently been followed by death. Dilatation by means of tents is

also transient in its results, and dangerous to life. Both Sims's

operation and dilatation by tents have given frequent and serious

warnings in the shape of pelvic inflammations, which, if not

destructive to life, have been almost as disastrous in their influence

upon health.

The following, with some modifications, is an abstract of a valuable

contribution[10] by Goodell of Philadelphia, in which he gives positive

endorsement to rapid dilatation as proposed by Ellinger and others. The

instruments recommended are two Ellinger dilators, which are preferred

on account of the parallel action of their blades. The dilatation is

commenced with the smaller instrument and completed with the larger,

which has powerful blades that do not spring or feather. The light

instrument needs only a ratchet in the handle, but the stronger one has

a screw which forces the handles together and the blades apart. To

prevent injury to the fundus when the instrument is open, the length of

the blades is limited to two inches. The larger instrument has a

dilating power of one and a half inches, and has a graduated arc in the

handles which indicates the divergence of the blades. Goodell's

modification of Ellinger's dilators is provided with serrated blades,

to prevent them from slipping out of the canal during the process of

dilatation.

[Footnote 10: _American Journal of Obstetrics_, 1884, p. 1179.]

For dysmenorrhoea or sterility due to flexion or stenosis the method of

operation is as follows: A suppository containing a grain of the

aqueous extract of opium is introduced into the rectum, the patient

etherized, and the uterus exposed by Sims's speculum. The cervix is

held by a tenaculum, and the smaller dilator is introduced as far as it

will go. Upon gently stretching open that portion of the uterine canal

which it occupies, the stricture above so yields that when the blades

are closed they will pass higher. By repeating this manoeuvre a

cervical canal is tunnelled out which before would not admit the finest

probe. Should the os {180} externum or cervical canal be too small to

admit the instrument, a pair of pointed scissors may be substituted,

and by the same opening and closing motions the canal may be prepared

for the introduction of the smaller dilator. As soon as the cavity of

the uterus has been entered the handles are brought together. This

dilator is then withdrawn, the larger one introduced, and its handles

slowly screwed together. If the flexure be very marked, the larger

instrument after being withdrawn should be introduced with its curve in

the opposite direction to that of the flexure, and the final dilatation

made with the dilator in this position. But in reversing the curve the

operator should take care not to rotate the organ upon its own axis,

and not to mistake a twist thus made for a reversal of the flexure; the

ether is then withheld, and the instrument allowed to remain in place

until the patient begins to flinch, when it is removed. The best time

for the dilatation is midway between the monthly periods. In the

majority of cases the dilatation should be carried to about one and a

quarter inches. The infantile uterus which has failed to develop at

puberty has thin, unyielding walls, and should therefore not be dilated

more than three-fourths of an inch or an inch. In using the larger

instrument it is usually necessary to have the assistant make decided

counter-traction with the vulsella forceps to prevent the blades of the

dilator from slipping out. The cervix is sometimes lacerated, but not

sufficiently to produce unpleasant results.

Goodell's statistics include one hundred and fifty operations of full

dilatation under ether, with no fatal result and without serious

inflammatory disturbance. As precautions against cellulitis,

peritonitis, and metritis the patient should be fortified for the

operation with moderate doses of opium and full doses of quinine, and

for two or three days after the dilatation this should be continued and

supplemented by the application of an ice-bladder over the abdomen.

After forcible dilatation under ether the cervical canal rarely returns

to its previously angular or contracted condition. The cervix shortens

and widens, and the plasma thrown out thickens and stiffens the uterine

walls. In a small minority of cases the operation must be repeated.

Dysmenorrhoea or sterility, if dependent solely upon the flexure, is

cured by the dilatation. The comparative safety of forcible dilatation

in the hands of a skilful and experienced gynecologist may be

contrasted with its great danger when undertaken by an operator

unacquainted with the special requirements of uterine surgery.

Peri-uterine inflammation is a positive contraindication to the

operation.

Post-uterine inflammation, which has drawn the anteflexed or anteverted

uterus upward and backward by the contraction of the utero-sacral

ligaments, often produces traction upon the vesico-vaginal wall and

neck of the bladder, with a constant desire to micturate. For the

relief of this intractable symptom, which sometimes goes on to

cystitis, Emmet has proposed a most satisfactory remedy known as his

buttonhole operation of urethrotomy.[11] He makes a longitudinal

opening about five-eighths of an inch long through the urethro-vaginal

wall, between the meatus and the neck of the bladder, without cutting

through either. To prevent the opening from healing together, the

margins of the mucous membrane of the urethra are united with fine

catgut sutures to the {181} margins of the mucous membrane of the

vagina. According to Emmet, the operation relieves irritation due to

traction on the neck of the bladder by freeing the pelvic fascia at the

fixed point where it converges to its pubic attachment. The operation

is equally applicable for the relief of this symptom when due to

inflammation in any other part of the pelvis. The same result may be

secured, but less satisfactorily, by forcible dilatation of the

urethra.

[Footnote 11: Emmet's _Principles and Practice of Gynecology_, 3d ed.,

pp. 275 and 761.]

From personal experience the author can testify to the gratifying

effects of this operation. Vesical irritation caused by post-uterine

inflammation and consequent contraction of the utero-sacral ligaments

is often wrongly attributed to the mechanical pressure of the

anteflexed fundus uteri upon the bladder, which is manifestly

impossible, if the contracted utero-sacral supports hold the entire

uterus back away from the bladder.

The various anteflexion and anteversion pessaries which have been

devised for the purpose of propping up the corpus are almost useless.

Their false reputation depends upon the relief which they frequently

give to complicating prolapse, the symptoms of which have been wrongly

attributed to anteflexion or anteversion. The same pessaries therefore

may be applied as in descent. (See Etiology and Clinical History of

Descent.) Intra-uterine stem pessaries designed to straighten the

flexed uterus are sometimes effective, and always dangerous.

{182}

DISORDERS OF THE UTERINE FUNCTIONS.

BY J. C. REEVE, M.D.

Menstruation with its disorders is the only subject to be considered

under this head. In its monthly recurrence it is most intimately

connected with, and dependent upon, ovulation, each menstrual discharge

being the sign and evidence of the maturation and expulsion of one ovum

or more. This proposition is denied by some, but the evidence adduced

against it, while sufficient to show that the two processes may be

dissociated, and may sometimes occur independently, is not strong

enough to invalidate the truth of the general statement.

Menstruation may be entirely absent, the flow may be excessive, or it

may be accompanied by severe pain; and these derangements have been

designated from time immemorial as amenorrhoea, menorrhagia, and

dysmenorrhoea. The time is long past, however, when these affections

could be treated as distinct diseases. Each of them may be caused by

influences so various--and, above all, may depend upon pathological

conditions so different, and even dissimilar--that the name applied to

each is indefinite, and, like the term dropsy, only incites inquiry as

to some abnormal condition of which the deranged flow is the symptom. A

due appreciation of this fact is of prime importance, because treatment

cannot be instituted with expectation of success until the particular

form of each derangement has been distinguished.

The great majority of cases of uterine derangement depend upon changes

of structure. Those considered purely functional are largely in the

minority, and would be still less in number with a more intimate

knowledge of pathology or with greater skill in examination. No

argument is needed, therefore, to show that a direct and thorough

examination of the organs concerned is essential to rational treatment

of this class of affections. There are obvious difficulties in the way

of such an investigation, different from and far greater than attend

the investigation of the diseases of any other organ of the body. With

tact and proper demeanor, however, these difficulties can be generally

overcome, but in any other than trifling cases, and especially in those

continuing for any considerable time, the practitioner will do

injustice to himself as well as to his patient if he do not insist upon

this indispensable investigation.

A due appreciation of the influence of uterine disorders and diseases

upon other and remote parts of the body is necessary to a correct

estimate of their importance, and often of great practical value in

treatment. Through the sympathetic nervous system pathological

conditions of the uterus modify the processes of organic life, and by

direct or reflex action {183} affect the cerebro-spinal system in its

centre or at any point of its terminal ramifications. That the stomach

responds readily to uterine excitations is shown in pregnancy, and

uterine disease often causes disorders of the digestive organs the

origin of which may not be suspected. Eructations, vomiting, and the

various forms of indigestion are not uncommon. The bowels are irregular

in action, constipation alternating with diarrhoea, and flatulent

distension may occur even to a degree demanding special treatment.

Failure of general nutrition and impoverished blood are the

consequences of this disturbed digestion; without good blood there is

no sound innervation, and the nervous system is soon in such a

condition as to respond unduly to even insignificant impressions.

Normal menstruation is marked by a nervous erethism which shows itself

by irritability, fits of despondency, and exhibitions of temper. There

are therefore abundant reasons why nervous diseases should be very

frequently seen as a remote effect of uterine disorders.

A very large proportion of these reflex diseases first occur at the

period of puberty, many present striking exacerbations at every

menstrual period, and some are so closely associated with this function

as to be cured only by remedies addressed to it. Headache, neuralgia,

hysteria in its varied forms, chorea, catalepsy, epilepsy, and even

mania, have been repeatedly shown to have their origin in the sexual

organs. The reproach often directed at gynecologists, of a disposition

to magnify their specialty, falls pointless before such important

facts; and since it is not uncommon for diseases of organs in close

proximity to the uterus, as those of the urethra, bladder, and rectum,

to be mistaken for or confounded with diseases of the uterus itself,

there is abundant warrant for urging the closest scrutiny as to a

possible uterine origin of remote diseases, especially those of a

nervous character.

Amenorrhoea.

The term amenorrhoea signifies the absence of menstruation. It occurs

in two different forms: First, those cases in which menstruation has

never occurred--emansio mensium; second, those in which it has

disappeared after having been established--suppressio mensium.

The following pathological schedule may assist in the study of the

subject. It need scarcely be said that it is not presented as correct

in every particular, nor with the idea that the dividing-lines between

physiological and pathological conditions can be always determined, but

as a convenient guide to follow in the study of the subject:

A. Amenorrhoea (absent menstruation) from

_a_, anatomical conditions: want of development of organs,

atresia of passages;

_b_, physiological influences: delayed puberty, idiopathic;

_c_, pathological causes: constitutional diseases, disease of the

sexual organs, the cachexiæ.

B. Amenorrhoea (secondary or suppressed menstruation):

_a_, anatomo-pathological: atresia of passages, atrophy of

organs;

_b_, physiological: pregnancy, nursing, premature change of life;

_c_, pathological: besides those given above--A-_c_--are

psychical influences and exposure or taking cold during

menstruation.

{184} Absence or want of due development of some of the sexual organs

is not of very infrequent occurrence. The ovaries are very rarely found

wanting; they are more often checked in development and present the

characteristics of early life. This condition may be the cause of

delayed, irregular, or scanty menstruation, making a more or less near

approach to amenorrhoea. Absence of the uterus is often combined with

absence or with an undeveloped condition of the vagina, but this canal

may be perfect and no change of the external organs be present to

indicate that the uterus is wanting. It may also exist in a rudimentary

form, and may be found corresponding in size and shape to the uterus of

any period of early life.

Absence of the ovaries not only causes amenorrhoea, but checks the

progress of the bodily development and prevents the sexual changes of

puberty. When the ovaries are wanting there is almost always absence of

the Fallopian tubes, uterus, and vagina. The symptomatology of absence

of the uterus is not generally striking, the lack of menstruation being

the principal sign; exceptionally, however, it is otherwise. In some

cases where the ovaries are present and the uterus wanting, the most

aggravated affections of the nervous system show themselves.

Congenital atresia of the genital canal may occur in any part of its

course. Imperforate hymen is the most frequent as it is the least

dangerous form, being more than twice as common as atresia of the

vagina and three times as frequent as that of the cervix uteri. The

vagina may be extremely small in calibre, closed in part or the whole

of its course, or only a fibrous cord indicate where it should be. The

uterus may be closed at the internal or external os; the latter is the

more frequent. An occlusion at one point does not preclude the

existence of other closures higher up. The effect of a closed canal

with a recurring secretion above is evident, and gives rise to a

well-marked class of cases. The organs above become distended, and the

distension increases until an opening is made by art or the retained

fluid bursts a passage for escape. This may occur outwardly with

immediate relief and cure, or into the peritoneal cavity, causing

speedy death. The time at which the uterus may be expected to give way

under such distension cannot be stated, as the power of resistance of

the organ differs and the amount of secretion each month may vary

widely. Scanzoni in one case evacuated eight pounds of blood, the

result of seven months' accumulation, and found the uterine wall as

thin as paper. Bernutz states that the average time before interference

is necessary is three or four years, and gives a case first operated

upon in the tenth year of its course.

Menstrual retention is not at first indicated by pronounced symptoms.

Suspicion of the nature of the case may be first excited by the

severity of those symptoms which at every period announce the approach

of menstruation and known as the menstrual molimen. As distension

increases these become extreme, with rectal and vesical tenesmus and

severe uterine colic. The nervous system sympathizes, as with all

menstrual derangements, and there may be rigor, fainting, or even

convulsions.

Whenever a patient presents such symptoms an examination should be

insisted upon. It will generally reveal a smooth, soft, and fluctuating

tumor, projecting externally if the case be one of imperforate hymen,

or higher up if the vagina be occluded. If the uterus has become

distended, {185} there will be a round, smooth, elastic tumor above the

pubes. Diagnosis will be more or less difficult according to the seat

of the obstruction. Cases of imperforate hymen may be readily diagnosed

by sight, if touch and the history are not sufficient. When the

occlusion is deeper, the patient should be placed under the influence

of an anæsthetic. By one finger in the rectum and the thumb in the

vagina, and a sound in the bladder, the seat and extent of the

obstruction may be determined. Should it be necessary, the urethra may

be dilated and a finger passed into the bladder in order to make a

diagnosis. Rectal exploration is of great assistance in discovering the

uterine enlargement and its character. Scanzoni calls attention to the

difference in the cervix when the atresia is at the internal or

external os. In the latter case the cervix will be obliterated; in the

former, it will be unchanged. With a perfect vagina and a cervix of

this character retention may be taken for an early pregnancy,

especially as it is not uncommon for sympathetic mammary symptoms and

gastric troubles to be present. Time will demonstrate the nature of the

case if a diagnosis cannot be made at once.

The age at which the menstrual flow is established varies greatly. The

average age of puberty in this country, as appears from Emmet's tables

made up of 2330 cases, is 14.23 years, and these are believed to be the

only American statistics. A close correspondence may be noted between

this and the statistics of the four largest cities of France, which

give 14.26 as the average. But that it is not unusual for the

appearance of menstruation to be delayed is shown by the fact that of

the above 2330 cases, 288 only menstruated at sixteen years and 254

more between that age and twenty-three. The circumstances which may

influence, within physiological limits, the appearance of menstruation

should be considered in connection with cases of this kind. Climate and

social position are the principal ones. The epoch of puberty descends

in the scale of age in proportion to the average height of the

temperature of various countries, and vice versâ. Social position and

city life show a marked effect in hastening puberty as compared with

the simpler manners and plainer life of rural populations. It amounts

to an average of something over a year, and is explained by the

influence of enervating and luxurious habits, of light reading and the

drama, the chief subject of both being the grand passion, but

especially of a freer intercourse between, and the co-education of, the

sexes, and the greater extent to which music is cultivated and enjoyed.

Among pathological conditions giving rise to amenorrhoea it would seem

that disease of the ovaries should occupy the first rank in frequency

and importance. The reverse is the truth. The ovaries are rarely

inflamed, and when so amenorrhoea is not always the result. They are

frequently the seat of cystic degeneration, producing tumors of large

size, yet so long as but a small portion of one of the organs remains

unaffected Graäfian vesicles may still be furnished and menstruation

continue. It is by the influence of remote pathological conditions that

the menstrual flow is most frequently restrained, and especially by

those general affections known as cachexiæ, all of which exhibit marked

depression and low grade of vital power and activity, if not more

pronounced pathological processes. Chlorosis, the relations of which to

menstruation are intimate, and which seems to be sometimes the

offspring of {186} amenorrhoea, exerts a marked retarding influence,

amounting to an average of one year and a half. The scrofulous cachexia

is still more potent: Scanzoni states that of 31 well-marked cases, in

19 menstruation did not occur until the twenty-first year.

Amenorrhoea which is the result of pulmonary tubercular disease comes

frequently under observation. It may occur at a very early period of

the disease, before there is any great amount of deposit in the lungs,

when it is rather the expression of want of vital force than of the

exhausting effect of the disease. Under these circumstances it is only

to the laity a subject of serious consideration; to the physician it is

but a symptom.

A system of practical medicine. By American authors. Vol. 4 · 第 21 / 116 段