If then the passions are so necessary to the support of the health of

the body, when in a proper degree, can we expect, that when they are

inordinate or excessive, or even deficient, we shall escape with

impunity? tumultuous passions are like torrents, which overflow their

bounds, and tear up every thing before them; and mournful experience

convinces us, that these effects of the mind are easily communicated

to the body. We ought, therefore, to be particularly on our guard

against their seduction.

"'Tis the great art of life to manage well

The restless mind."

It is particularly in their infancy, if it may be so called, that we

ought to be upon our guard against their seduction; they are then

soothing and insidious; but if we suffer them to gain strength, and

establish their empire, reason, obscured and overcome, rests in a

shameful dependence upon the senses; her light becomes too faint to

be seen, and her voice too feeble to be heard; and the soul, hurried

on by an impulse to which no obstacle is presented, communicates to

the body its languor and debility. The passions, by which the body is

chiefly affected, are, joy, grief, hope, fear, love, hatred, and

anger. Any others may be reduced to some of these, or are compounded

of them. The pleasurable passions produce strong excitement of the

body, while the depressing passions diminish the excitement; indeed

it would seem that grief is only a diminution of joy, as cold is of

heat; when this passion exists in a proper degree, then we feel no

particular exhilarating sensation, but our spirits and health are

good: we cannot doubt, however, that we are excited by a pleasant

sensation, though we are unable to perceive it. In the same manner,

when heat acts moderately, or is about the degree we call temperate,

we do not perceive its effects on the body, though there can be no

doubt, that the body is under the influence of its stimulus, and

powerfully excited by it; for when it is diminished, or cold applied,

we feel a deficiency of excitement, and become afterwards more

sensible of heat afterwards applied.

The same takes place with respect to joy and grief, and proves, I

think, clearly, that the one is only a diminution of the other, and

that they are not different passions. When the body has been exposed

to severe cold, the excitability becomes so much accumulated with

respect to heat, that if it be afterwards applied too powerfully, a

violent action, with a rapid exhaustion of the excitability, which

ends in mortification, or death of the part, will take place. We

should therefore apply heat in the gentlest manner possible, and

gradually exhaust the morbidly accumulated excitability.

In the same manner, when the body has been under the influence of

violent grief, any sudden joy has been known to overpower the system,

and even produce instant death. We have an instance in history, of a

mother being plunged into the extreme of grief, on being informed

that her son was slain in battle; but when news was brought her, that

he was alive, and well, the effect upon her spirits was such, as to

bring on instant death. This event ought to have been unfolded to her

in the most gradual manner; she should have been told, for instance,

that he was severely wounded; but that it was not certain he was

dead; then that there was a report he was living, which should have

been gradually confirmed, as she could bear it. The same observations

may be made, with respect to hope and fear, or despair; the former is

an exciting passion, the latter, a depressing one; but the one is

only a lower degree of the other; for a moderate degree of hope

produces a pleasant state of serenity of the mind, and contributes to

the health of the body; but a diminution of it weakens; and a great

degree of despair so accumulates the excitability of the system, as

to render it liable to be overpowered by any sudden hope or joy

afterwards applied. What proves that joy and hope act by stimulating,

and grief and despair by withdrawing stimulant action from the body,

is, that the former exhaust excitability, while the latter accumulate

it. Joy, for instance, does not render the system more liable to be

affected by hope, but the reverse; and the same may be said of hope.

In the same way, heat does not render the body more liable to be

affected by food, but the reverse. Both these are stimulants, and

exhaust the excitability. But after heat has been applied, if it be

followed by cold, a great degree of languor or weakness will take

place; because we have here a direct debility, added to indirect

debility. In the same way, grief succeeding joy, or despair

succeeding hope, produce a greater degree of dejection, both of mind

and body, than if they had not been preceded by these stimulant

passions; because here, direct debility is added to indirect. The

excitability is first exhausted, and then the stimulus is withdrawn.

We see then, that the passions of the mind act as stimulants to the

body, that, when in a proper degree, they tend to preserve it in

health; but when their action is either too powerful, or too small,

they produce the same effects as the other powers. We should

therefore naturally expect, that when there is a deficient action of

this kind of mental stimulus, or when the mind is under the influence

of the depressing passions, a predisposition to diseases of direct

debility would take place, and even these diseases be produced.

Accordingly we find a numerous class of nervous complaints

originating from these causes. Indeed, the undue action of the mental

stimulants, produces more quick alterations in the state of the

excitement, than that of the other exciting powers. Violent grief, or

vexation, will immediately suspend the powers of the stomach. If we

suppose a person in the best health, and highest good humour, sitting

down to dinner with his friends, if he suddenly receives any

afflicting news, his appetite is instantly gone, he cannot swallow a

morsel. If the same thing happens after he has made a hearty dinner,

the action of the stomach is suddenly suspended, and the whole

process of digestion stopped, and what he has eaten, lies a most

oppressive load. But this is not all: the whole circulation of the

blood becomes disturbed; the contraction and dilatation of the heart

become irregular; it flutters, and palpitates; hence all the

secretions become irregular, some of the glands acting too

powerfully, others not at all; hence the increased action of the

kidneys, and hence a burst of tears; hysterical affections, epilepsy,

and syncope, frequently succeed, in which every muscle of the body

becomes convulsed. Indeed, many terrible diseases originate from this

source, which were formerly ascribed to witchcraft, and the

possession of devils.

In slower, more silent, but longer continued grief, the effects are

similar, but not so violent. The functions of the stomach are more

gently disturbed, its juices vitiated; and acidity, and other

symptoms of indigestion, will show themselves. Hence no bland and

nutritive chyle is conveyed into the blood; whence emaciation and

general debility must follow; and the patient will at last die, as it

is said, of a broken heart.

Besides the disturbed state of the stomach, and bad digestion, there

can be no sleep in this state of mind; for,

"Sleep, like the world, his ready visit pays,

Where fortune smiles; the wretched he forsakes;

Swift on his downy pinion flies from woe,

And lights on lids unsullied with a tear."

Hence the animal spirits will not be recruited, nor the worn out

organs restored to vigour.

The minds of patients labouring under this division of nervous

diseases, are likewise in general filled with over anxiety concerning

their health; attentive to every feeling, they find, in trifles light

as air, strong confirmations of their apprehensions.

It is evident, that in these cases, a state of direct debility

prevails, attended with a morbidly accumulated excitability; hence,

those remedies afford relief, which produce a quick exhaustion of

this principle, and thus blunt the feelings, and lull the mind into

some degree of forgetfulness of its woes. Hence opium, tobacco, and

the fetid gums are often resorted to; and in the hands of a judicious

practitioner, they will afford great relief, provided he carefully

watch the patient, and prevent their abuse; for, if left to the

discretion of the patient, he finds that kind of relief which he has

long wished for; his moderation knows no bounds, and he is apt to

take them in such a manner, as to add indirect debility, to direct,

and thus bring on a state of exhausted excitability, while there is

still a diminished state of mental stimulants. This will cause his

spirits to be more depressed than ever; he will therefore increase

the dose, whether it be of opium, tobacco, or spirituous liquors, and

thus he will be hurried on, adding fuel to the flame, till his

exhausted excitability becomes irrecoverable, and he ends his days in

a miserable state of imbecility, if not by suicide. Hence, though

some of these narcotic stimulants, which exhaust the excitability,

and blunt the feelings, may be employed with advantage, in order to

prepare the mind for those changes, which the physician wishes to

produce, they should be used with the greatest caution, and never

left in any degree to the discretion of the patient. The cure,

however, depends chiefly on regulating the state of the mind, or

interrupting the attention of the patient; and diverting it, if

possible, to other objects than his own feeling.

Whatever aversion to application of any kind we may meet with in

patients of this class, we may be assured that nothing is more

pernicious to them than absolute idleness, or a vacancy from all

earnest pursuit.

The occupations of business suitable to their circumstances, and

situations in life, if neither attended with emotion, anxiety, nor

fatigue, are always to be advised to such patients; but occupations

which are objects of anxiety, and more particularly such as are

exposed to accidental interruptions, disappointments, and failures,

are very improper for patients of this class.

To such patients exercise in the open air is of the utmost

consequence. Of all the various methods of preserving health and

preventing diseases, which nature has suggested, there is none more

efficacious than exercise. It puts the fluids all in motion,

strengthens the solids, promotes digestion, and perspiration, and

occasions the decomposition of a larger quantity of air in the lungs,

and thus not only more heat, but more vital energy is supplied to the

body; and of all the various modes of exercise, none conduces so much

to the health of the body, as riding on horseback: it is not attended

with the fatigue of walking, and the free air is more enjoyed in this

way, than by any other mode of exercise. The system of the vena

portarum, which collects the blood from the abdominal viscera, and

circulates it through the liver, is likewise rendered more active, by

this kind of exercise, than by any other, and thus a torpid state,

not only of the bowels, but of this system of vessels, and the

biliary system, is prevented.

When a patient of this class, however, goes out for the sake of

exercise only, it does not in general produce so good an effect, as

might be expected; for he is continually brooding over the state of

his health: there is no new object to arrest his attention, and he is

constantly reminded of the cause of his riding. Exercise will

therefore be most effectual when employed in the pursuit of a

journey, where a succession of pleasant scenes are likely to present

themselves, and new objects arise, which call forth his attention. A

journey likewise withdraws the patient from many objects of

uneasiness and care, which might present themselves at home.

With respect to medicines, costiveness, which often attends these

diseases, ought to be carefully avoided, by some mild laxative.

Calcined magnesia, and lemonade, have always seemed to me to answer

the purpose; but the most effectual method is to acquire a regular

habit, which may be done by perseverance, and strict attention.

Chalybeate waters have been frequently tried, and may in general be

recommended with success, particularly, as the amusement and exercise

generally accompanying the use of these waters, aid the tonic powers

of the iron. The bark may likewise be exhibited with advantage.

There is yet another class of nervous diseases which we have to

notice, which are by no means uncommon; yet they have, like the first

class, escaped the attention of writers on this subject, and of

medical practitioners in general: I mean those where the system is in

a state of torpor, or exhausted excitability.

This state of the system may be brought on by various causes, but

principally by the long continued use of opium, tobacco, or fermented

liquors.

When these substances, which are powerful stimulants, have been taken

for some time, they bring on a state of the system so torpid, that

the usual exciting powers, and the usual occurrences, which in

general produce pleasant sensations, do not occasion a sufficient

degree of excitement, in those whose excitability is thus exhausted.

They therefore feel continual languor and listlessness, unless when

under the influence of the stimulus which brought on the exhaustion.

Every scene, however beautiful, is beheld with indifference by such

patients, and the degree of ennui they feel is insupportable: this

makes them have recourse to the stimulus which has exhausted their

excitability, which in some degree removes this languor for a time;

but it returns with redoubled strength, and redoubled horror, when

the stimulant effect is over: and as this repetition exhausts the

excitability more and more, the stimulus is repeated in greater

quantity, and thus the disease increases to a most alarming degree.

There is no way of curing this state of nervous torpor, but by

leaving off the stimuli which caused the exhaustion; and if the

patient have resolution to do this for a few weeks, though, at first,

he will, no doubt, find his spirits a little depressed, he will

ultimately overcome the habit, and will be rewarded by alacrity of

spirits, such as he never experiences under the most powerful action

of artificial stimulants.

I must not, however, forget to notice, that there is a nervous state,

or ennui, originating from a wrong direction of mental exertion,

which exhausts the excitability to a great degree, and brings on a

state of depression scarcely to be born.

When a person has by habit made his mind constantly dependent on

dissipation, on gaming, and on frivolous, but not inactive pursuits,

in order to produce pleasurable sensations, and at the same time

neglected that culture of the understanding which will enable him to

retire into himself with pleasure, and receive more enjoyment from

the exercise of this cultivated understanding than he does in the

most noisy, or fashionable circle of dissipation: I say, when there

is this vacancy of mind, whenever it is not engaged in such pursuits

as I have mentioned, a languor and weariness is experienced, which is

intolerable, and which prompts the person so circumstanced, to fly

continually to the only scenes which interest his mind. Hence, the

passion for gaming, in which the anxiety attending it causes an

interest in the mind, which takes off the dreadful languor

experienced, when it is not thus employed.

It is owing to wealth, admitting of indolence, and yielding to the

pursuit of transitory and unsatisfying amusements, or to that of

exhausting pleasures only, that the present times exhibit to us so

many instances of persons suffering under this state: it is a state

totally unknown to the poor, who labour for their daily bread, and to

those whose minds are actively employed in study or business. It can

only be cured by cultivating the understanding, and applying to some

art or science, which will engage and interest the attention. I have

received the thanks of many for recommending the study of philosophy,

and particularly of chemistry, to their attention. This affords a

rational and interesting pursuit, which, if entered into with ardour,

and if the person actually works, or makes experiments himself, he

will soon experience an enjoyment and an interest, such as he never

experienced at the gaming table, or at any other place of fashionable

amusement. Nay, I will venture to say, that all elegant amusements

will be enjoyed with much greater relish by one who employs himself

in some rational pursuit, and only resorts to such amusements as a

relaxation, than by one who makes these amusements a business.

From the view we have taken of these complaints, it is evident, that

they are like other general diseases of the sthenic, or asthenic

kind; they seem to constitute a state of the body between

predisposition and disease; and they differ from most diseases in

this, that in most complaints the increase, or diminution of the

excitement is unequal in different parts of the body, and this gives

rise to the different forms of disease; but in nervous complaints the

excitement seems much more equably affected in different parts. These

complaints, as we have seen, may be divided into three classes;

sthenic; those of accumulated excitability; and those of exhausted

excitability: but though they are evidently distinguishable in this

manner, and require different modes of cure, I have never seen any

account of more than one kind in any medical writer: the same

remedies were prescribed for all, however different they might be.

Though medicines may relieve complaints of this kind, and

particularly those of the second class, yet from what has been said,

it must be evident, that much more may be done by regulating the

action of the common exciting powers. Indeed, this is the case in

most chronic diseases. Exercise and temperance will do infinitely

more than medicine. By their means, most diseases may be overcome;

but without them we may administer drugs as long as we please.

Voltaire sets this advice, which I have frequently inculcated, in so

strong a light, that it may perhaps carry more conviction than any

thing I can say. Ogul was a voluptuary, ambitious of nothing but good

living: he thought that God had sent him into the world for no other

purpose than to eat and drink: his physician, who had but little

credit with him, when he had a good digestion, governed him with

despotic sway, when he had eaten too much.

On feeling himself much and seriously indisposed by indolence and

intemperance, he requested to know what he was to do, and the doctor

ordered him to eat a basilisk, stewed in rose water, which he

asserted would effect a complete cure. His slaves searched in vain

for a basilisk; at last they met with Zadig, who was introduced to

this mighty lord, and spoke to him in the following terms.

"May immortal health descend from Heaven to bless all thy days! I am

a physician: at the report of thy indisposition, I flew to thy

castle, and have now brought thee a basilisk, stewed in rose water.

But, my lord, the basilisk is not to be eaten; all its virtue must

enter through thy pores. I have enclosed it in a little ball, blown

up and covered with a fine skin. Thou must strike this ball, with all

thy might, and I must strike it back for a considerable time: and by

observing this regimen for a few days, thou wilt see the effects of

my art." The first day Ogul was out of breath, and thought he should

have died with fatigue; the second he was less fatigued, and slept

better. In eight days he recovered all the strength, all the health,

all the agility and cheerfulness of his most agreeable years. Zadig

then said unto him, "there is no such thing in nature as a basilisk;

but thou hast taken exercise, and been temperate, and hast recovered

thy health." In the same manner I say, that temperance and exercise

are the two great preservers of health, and restorers of it when it

is lost; and that the art of reconciling intemperance and health is

as chimerical, as washing the Ethiopian white.

It will easily be perceived that the system of animal life which I

have investigated, may be applied to all other general diseases, as

well as the gout and those called nervous: I have merely given a view

of these by way of specimen of its application.

Should these lectures contribute in any degree to lessen the future

sufferings of my hearers, or any of their friends, I shall not have

delivered them in vain. To be assured of this, would be the greatest

pleasure that I could receive.

THE END.

From the Press of the Royal Institution of Great Britain,

Albemarle Street, London: W. Savage, Printer.

INDEX.

A.

_Air_, its properties--its components

_Animals_, specific temperature of

_Appetite_, artificial

_Arteries_, their structure and office

_Assimilation_, from the blood

_Attention_, fixed on new objects

B.

_Banks, Sir Joseph_, his almost fatal experience of cold

_Beddoes, Dr._ his remarks on temperature,

_Bile_, its properties

_Blood_, difference between arterial and venous

contains iron

changes produced on, by the different gases

assimilation from

_Bones_, mechanism of

structure of

_Brown, Dr. John_, his example followed

declines a definition of excitability

denies the existence of sedatives

his cure of diseases of exhaustion objected to

his theory will be as durable as Newton's philosophy

not aware of the extent of his own theory

C.

_Camera obscura_

_Colour_ of different nations

_Cooper, Mr. Astley_, successfully perforates the tympanum of the ear

_Circulation_ of the blood

through the lungs

through the liver

affected by centrifugal force

discovered by Harvey, and derided

_Cullen, Dr._ his system defective

_Currie, Dr._ his treatment of typhus

D.

_Darwin, Dr._ quoted

_Digestion_, organs of

process of

diseases affecting

_Diseases_

sthenic

asthenic

fallacy of symptoms

_Diseases_, method of cure

spasmodic, of extreme vess.

classification of

nervous and bilious (so called)

of the poor

_Dollond, Mr._ his achromatic lenses, first suggested by Dr. David

Gregory

E.

_Ear_, description of

diseases of

tympanum perforated

_Electricity_, phenomena of

useful in gout

_Excitability_, or vital principle

how affected by heat, food, air, &c.

accumulated by sleep

three states of

its accumulation, and exhaustion illustrated

an unknown indefinable somewhat

connected with oxygen

hypothesis respecting this connexion

scale of

how to be regulated in gout

_Exercise_

on horseback, best

_Eye_, description of

vertical section of

its accommodating power

F.

_Food_, animal and vegetable

in gout

G.

_Galvanism_, its identity with electricity

accompanies oxydation

_Gaming_, &c. deplorable effects of, on the mind

_Gases_, their proportions in the atmosphere

changes they produce on the blood

_Gastric Juice_, dissolves food

proved by experiment

_Gout_

denied to be salutary, or incurable

not to be cured by drugs

not hereditary

mode of attack

depends not on morbific matter

its inflammation asthenic

its symptoms and description

its remissions accounted for

the terms retrocedent, atonic, &c. misapplied

mode of cure

electricity useful

Dr. Darwin's advice

Diet and medicine in

_Gravity_, the circulation affected by it

H.

_Habit_, its power

_Harvey_, discovers the circulation of the blood, and is opposed

_Health_

previous to disease, investigated

point of, on the scale

_Heart_, description of

_Heat_, its combinations

animal, accounted for

its effects on the system

how it affects vegetables

its debilitating effects exemplified

_Hunger_ and _thirst_

_Hunter, Mr. John_, dissects torpedo, and electrical eel

I.

_Inflammation_, illustrated

sthenic

asthenic

of gout asthenic

_Iron_, contained in the blood

L.

_Lacteals_, described

_Life_, principle of

_Light_, its properties

its exciting power

_Lungs_, circulation through

_Lymphatics_ described

M.

_Muscles_, mechanical action of

_Music_, its effects

N.

_Nerves_, their distribution

_Nervous_ and _bilious_, terms sometimes used without ideas

diseases (so called)

diseases really so

_Newton_, his query about elastic fluid misapplied

even his conjectures important

discovers the laws of sound

his reason why the crystalline is densest in the middle

knew not the cause of gravitation

_Nonnaturals_, misapplication of that term

_Nosology_

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