We have seen then, that by the theory which has been unfolded, all

the symptoms of this hitherto mysterious disease are plainly and

naturally explained. We shall next see if the only method of cure

which experience warrants, cannot be explained upon the same

principles.

If, on entering this part of the subject, any one should expect that

I should furnish him with a receipt, consisting of certain drugs,

which swallowed, will cause this terrible disease to disappear, and

health to take its place, he would be very much mistaken; for, can

any person in his senses suppose that a disease, which he has been

almost his whole life in contracting, and an exhausted state of the

excitability, which has been gradually brought on by years of

intemperance, can be dispersed by a pill, a powder, or a julep? Or,

if the symptoms could be relieved by medicine, which they often may,

can he suppose, that they will not return, if the same mode of

living, which first brought them on, be continued?

I shall, however, proceed to give some directions, which if rigidly

persevered in, will not only afford relief in the fit, but will

prevent its return with such violence, and at last totally eradicate

it, provided the constitution be not completely exhausted, and almost

every joint stiffened with calcarious concretions.

The inflammation of the extremities may at any time be relieved by

means of electricity, or by stimulant embrocations applied to the

part, and this without any danger whatever of throwing the complaint

on some more vital part, as has generally been imagined. If I were to

apply any debilitating means to the part, I should then probably

relieve the pain; but, by debilitating the whole system, should cause

an attack of the stomach, or some other internal part, as has been

already explained; but by a stimulant application to the inflamed

part I run no such risk. The inflammation is of the asthenic kind,

depending upon a debility of the small vessels, whereby they do not

afford sufficient resistance to the propelling force, and therefore

become morbidly distended, or inflamed, as it is termed, though this

term is certainly improper, even in a metaphorical view: but a

stimulant application to the part excites the debilitated vessels to

action; their contraction diminishes the morbid quantity of blood;

and the balance between the propelling and resisting forces being

restored, the inflammation of course ceases. This is not a mere

deduction, a priori, from the theory of inflammation, which I have

delivered; it is the result of repeated experience. I have seen

several very violent gouty inflammations very speedily removed by

electricity. Small sparks should be drawn from the part affected, at

first through flannel, and increased as the patient can bear them:

sparks alone are necessary; recourse need never be had to shocks. But

though we thus remove a very painful part of the disease, yet still a

formidable debility remains, and unless this be removed, the

inflammation will be apt to return. In endeavouring to remove this

general debility, we must recollect, that it is of the indirect kind,

or depends upon an exhausted state of the excitability; our great

object therefore, is to allow the excitability to accumulate. But

this accumulation depends as well upon the proper action of the

different functions, as upon the withdrawing of stimulants: we ought

therefore to guard carefully against costiveness, by which the proper

action of the stomach and bowels is very much injured: but we must

use warm laxatives. An infusion of senna and rhubarb in proof

spirits, made still stronger by aromatics, has always seemed to me to

answer the purpose best, and this should be taken of a temperature

rather above blood warm; for instance, about 100 degrees. This is

particularly necessary, when the gout attacks the stomach, and I have

several times seen a severe attack of it removed in half an hour, by

a tincture of this kind. Indeed, the most violent attacks of the

stomach may be relieved; and are only to be relieved by spirits,

ether, and opium.

It is on this organ, that the hurtful powers have produced their

greatest effect; for to it they are immediately applied. It is by no

means surprising, that the constant application of highly seasoned

foods, with fermented and spirituous liquors, should at last wear out

the vital principle of this organ. Indeed it is often so far

exhausted, that the most terrible cramps and convulsions take place,

which would soon end in its total extinction, unless it were roused

to somewhat like a proper action by the most powerful stimulants.

Still, however, their effect is but temporary.

With respect to a regular fit, after the inflammation of the

extremities has been subdued by the means I have mentioned, a

generous, but not full diet should be used. A person who has been for

a long time accustomed to wine, cannot easily be deprived of it at

once; but he should drink Madeira, and those wines, which neither

contain much carbonic acid, nor deposite much tartar. His food should

be of the plainest kind, and generally boiled, instead of roast. The

great thing is to keep the spirits and excitement rather under par,

but not to let the patient sink too low. In this way, the exhausted

excitability will gradually accumulate, and the healthy state be

reestablished. When this is once effected, the gout may be prevented

in future with the greatest certainty, if the patient will have

resolution. The whole secret consists in abstaining, in toto, from

alcohol, in every form, however disguised, or however diluted. He

must not take it, either in the form of liqueurs, cordials, wine, or

even small beer.

I believe there never was an instance of a person having the gout,

who totally abstained from every form of alcohol, however he might

live in other respects: and I doubt very much, if ever the gout

returned after a person had abstained from fermented or spirituous

liquors for two years.

Temperance in eating, and exercise, are, no doubt, powerful

auxiliaries, and tend very much to promote health; but still they

will not secure a person from a return of the gout, without this

precaution. There seems something in alcohol, which peculiarly brings

on this state of the constitution, and without it, it would seem that

gout could not be produced. Here then is an effectual method of

curing the gout, which will no more return, if this method be

strictly persevered in, than the smallpox will attack the

constitution after inoculation.

During the fit therefore, I would say, nearly in the words of Dr.

Darwin, Drink no malt liquor on any account. Let the beverage at

dinner consist of two glasses of Madeira, diluted with three half

pints of water; on no account whatever drink any more wine or

spirituous liquors in the course of the day. Eat meat constantly at

dinner, without any seasoning, but with any kind of tender

vegetables, that are found to agree. When the fit is removed, use the

warm bath twice a week, an hour before going to bed, at about 93

degrees, or 94 degrees of heat. Keep the body open by means of

lenitive electuary and rhubarb; for there is an objection to the

tincture I mentioned, as containing alcohol. Use constant, gentle

exercise; but never so violent as to bring on great fatigue. The

grand secret, however, in the cure, as has been already observed, but

which cannot be too often inculcated, is to abstain, in toto, from

every thing that contains alcohol.

In short, though in acute diseases medicines are highly useful, a

chronic disease can never be cured, and the healthy state

reestablished, by them alone. To effect a cure in such cases, we must

reform our mode of life, change our bad habits into good ones; and

then, if we have patience to wait the slow operations of nature, we

shall have no reason to regret our former luxuries.

LECTURE XIV.

NERVOUS COMPLAINTS, &c.

In this lecture I propose to take a view of some of those affections,

which have been commonly, but improperly known by the appellation of

nervous complaints, because it has been supposed by many that they

are owing to a deranged state of the nerves, which, however, is by no

means the case; for I hope to be able to make it appear, that these

symptoms arise from a general affection of the excitement of the

system. In short, by far the greater number of these complaints,

arise from such a state of the excitement as approaches

predisposition, or perhaps ranges between predisposition and disease,

but does not in general actually reach disease; or rather, it is a

state of the excitement, so far departing from the point of perfect

health, that the functions are not performed with that alacrity, or

vigour, which ought to take place; but labour under that disturbed

and uneasy action, which, though it cannot be called actual disease,

yet deviates considerably from the point of perfect health.

This is a new view of these diseases, but the more I have examined

it, the more I am convinced that it is just. Indeed, the name,

nervous, has generally been given to an assemblage of symptoms, which

the physicians did not understand; and when the patient relates a

history of symptoms, and expects that his physician shall inform him

of the name, and nature of his complaint, he generally receives for

answer, that his complaints are nervous, or bilious; terms which

convey no distinct ideas, but which serve to satisfy the patient, and

to conceal the ignorance of the physician, or spare him the labour of

thinking.

Indeed, the idea of nervous diseases, which I have already pointed

at, is not only new, but could only have arisen from such a view as

we have been taking of the states of excitement and excitability.

This view will not only lead us to form a more just idea of the

manner in which these diseases originate, but will point out a

distinction of them into two classes, of the utmost use in practice,

but which distinction has totally escaped the attention of

practitioners; for though these complaints have been generally

thought to arise from a lowness of the nervous energy, or some kind

of debility, or weakness of the nervous system, and, on this account,

the stimulant and cordial plan of cure has been recommended, I am

convinced, from observation, that nearly one half of them, if not

more, originate from a state of the excitement verging towards

sthenic disease; and in these cases, this general mode of treatment

must be highly improper.

It has been already shown, that when the common exciting powers which

support life, act in such a manner, that a middle degree of exciting

power, acts upon a middle degree of excitability, the most perfect

state of the system, or a state of perfect health, takes place: it

is, however, seldom in our power so to proportion the state of

excitement and excitability to each other. The action of the exciting

powers is continually varying in strength; and the excitability, from

a variety of stimulants, and other circumstances, which are not

entirely under our direction, is sometimes more, and sometimes less

abundant, than this middle degree. There is, however, a considerable

latitude, on each side the point of health, within which the

excitement may vary, and yet no disease, nor any disturbance of the

functions may take place: but this has its limits, beyond which if

the excitement be brought, on either side, it is evident that an

uneasy or unpleasant exercise of the functions must take place. There

is not, however, any precise line or boundary between this state, and

that in which the functions begin to be disturbed; on the contrary,

the law of continuity and gradation seems to extend throughout every

part of nature. This departure from the healthy state, and approach

to disease, in which what has been called the nervous state consists,

is gradual and scarcely perceptible; but is apt to be produced by any

circumstances, which lead the excitement beyond its proper limits.

Nervous complaints may therefore be divided, like all other diseases,

into two classes. First, those in which the excitement is increased,

or in which it verges to, or has actually reached, the point of

predisposition to sthenic disease; Secondly, those in which the

excitement is diminished, or in which it verges towards asthenic

disease. This last class, as has been done before, may be subdivided

into two orders. The first will comprise those diseases in which the

excitability is sufficiently abundant, or even accumulated, but where

the excitement is deficient from a want of energy in the exciting

powers. In the second, there has been no deficiency in the action of

the exciting powers; but on the contrary, probably for a considerable

time, some of the diffusible stimuli not natural to life have been

applied; in this case, the excitability has become exhausted, and a

proper degree of excitement cannot be produced by the action of the

common exciting powers.

No diseases show so clearly the fallacy of trusting to symptoms, as

those of the former class. I have met with innumerable cases of this

kind, in which, if you were to trust to the patients own description,

they laboured under considerable debility; and had it not been for

the particular attention I paid to my own case, I should not probably

have suspected that a directly opposite state of the system may

produce these symptoms.

From inheriting a good constitution, and being brought up in the

country in a hardy manner, I am so much predisposed to the sthenic

state, that I may consider the state of my excitement, as generally,

indeed almost always, above the point of health: and unless I live in

the most temperate, and even abstemious manner, the excitement is

extremely liable to overstep the bounds of predisposition, and fall

into sthenic disease. I have had several attacks of this kind of

disease; and indeed, I never remember to have laboured under any

disease of debility, or diminished excitement.

Health, according to the view we have taken of it, may be compared to

a musical string, tuned to a certain pitch, or note; and though

perhaps in the great bulk of mankind, either from the manner of

living, or from other circumstances, the excitement is a little

below, and requires to be screwed up to the healthy pitch, yet there

are others where it is apt to get constantly above, and where it

requires letting down to this pitch; my constitution is one of these:

but I have this consolation, that if I can for a few years ward off

the fatal effects of some acute sthenic diseases, this tendency to

sthenic diathesis will gradually wear off, and I may probably enjoy a

state of good health, at a time, when most constitutions of an

opposite cast begin to give way. Whenever I have for some time lived

rather fully, though by no means intemperately, after having for some

days, or perhaps some weeks experienced an unusually good flow of

spirits, and taken exercise with pleasure, I begin, first of all, to

have disturbed sleep, I find myself inclined to sleep in the morning,

as if I had not been refreshed by the night's sleep; my spirits

become low, and I am apt to look upon the gloomy side of every thing

I undertake or do. I feel a general sense of languor and debility,

and am ready, as I have heard many patients labouring under the same

state exclaim, to sink into the earth. From the slightest causes, I

am apt to apprehend the most serious evils, and my temper becomes

irritable, and scarcely to be pleased with any thing. If in this

state, I take exercise, I soon feel myself fatigued; a disagreeable

stupor comes on, without, however, the least degree of perspiration,

and I feel an inability to move.

At first, I used to imagine these to be symptoms of debility, or

diminished excitement, nor was it till after several ineffectual

trials to relieve them by the tonic, or stimulant plan, that I was

convinced of my mistake. This plan always caused an aggravation of

every symptom, and if I persevered in it, an inflammatory disease was

sure to be the consequence. Indeed, I might have suspected this, from

considering, that these symptoms had been brought on by full living,

and preceded by good spirits; but my mind had received such a

prejudice from the writings of medical men, who had uniformly

described these as a train of nervous symptoms, as they called them,

depending on a debilitated state of the nervous system, that I was

blind to conviction, till repeated disappointment from the

stimulating plan, convinced me I must be wrong. The only alternative

therefore, was a contrary plan, and the immediate relief I

experienced, was a proof that I had detected the real nature of the

complaint. Since that time, I can at any time prevent these

unpleasant symptoms, by an abstemious course of life, and remove

them, when they have come on, by the debilitating plan; which,

instead of weakening, gives additional elasticity and strength to the

fibres, and alacrity to the spirits. I have described the symptoms in

one case, as this will serve as a general description. We may add,

that persons labouring under this kind of predisposition, are

particularly attentive to the state of their own health, and to every

change of feeling in their bodies; and from every uneasy sensation,

perhaps of the slightest kind, they apprehend great danger, and even

death itself. In cases of this kind, the bowels are generally

costive, and the spirits of the patient are very apt to be affected

by changes in the weather, particularly by a fall of the barometer.

How the diminution of atmospheric pressure acts in increasing the

symptoms, we perhaps do not know; but its effects are experienced

almost universally.

It is evident, that the only mode of cure in cases of this kind is

extreme temperance: animal food should be taken sparingly, and wine

and spirits in general totally abstained from. The bowels should be

kept open by any mild neutral salt. I have generally found magnesia

and lemonade to agree remarkably well in such cases. Exercise on

horseback, is also particularly useful; bark, bitters, and the fetid

and antispasmodic medicines, which are generally prescribed in such

cases, are extremely hurtful.

This view of nervous complaints is, I may venture to say, as new as

it is just. It has never been imagined, that any of them depended

upon too great excitement; on the contrary, they have been

universally considered as originating in debility, and of course,

tonics were prescribed, which, though they produced the greatest

benefit in the other class of nervous complaints, in these they

occasioned the most serious evils, and often brought on real

inflammatory diseases, or even diseases of indirect debility, as I

have repeatedly seen.

These cases cannot at first sight, however, be easily distinguished

from those of the opposite class; the symptoms being nearly alike,

and the patient complaining of languor, debility, and extreme

depression of spirits in both. But by attending carefully to the

effects produced by the exciting powers, they may in general be

distinguished. A patient of this kind will tell you, that he does not

feel pleasant effects from wine, or spirituous liquors; instead of

exhilaration, his spirits become depressed by them; whereas, in the

contrary state, he finds almost instant relief. By attending to

circumstances of this kind, the nature of the complaint may in

general be ascertained.

Highly seasoned, and strongly stimulant foods should in the sthenic

hypochondriasis, if it may be so called, be avoided; but the most

mischievous agent of all, and which contributes to bring on the

greater number of these complaints, is wine. This, I believe,

produces more diseases, than all other causes put together. Every

person is ready to allow, that wine taken to excess is hurtful,

because he sees immediate evils follow; but the distant effects,

which require more attentive observation to perceive, very few see,

and believe; and, judging from pleasant and agreeable feelings, they

say that a little wine is wholesome, and good for every one; and

accordingly take it every day, and even give it to their children;

thus debauching their natural taste in the earliest infancy, and

teaching them to relish what will injure their constitutions; but

which, if properly abstained from, would prove one of the most

valuable cordial medicines we possess.

The idea that wine or spirituous liquors assist digestion, is false.

Those who are acquainted with chemistry, know that food is hardened,

and rendered less digestible by these means; and the stimulus, which

wine gives to the stomach, is not necessary, excepting to those who

have exhausted the excitability of that organ, by the excessive use

of strong liquors. In these, the stomach can scarcely be excited to

action, without the assistance of such a stimulus. If the food wants

diluting, water is the best diluent. Water is the only liquor that

nature knows, or has provided for animals; and whatever nature gives

us, is, we may depend upon it, the best, and safest for us. Wine

ought to be reserved as a cordial in sickness, and in old age; and a

most salutary remedy would it prove, did we not exhaust its power by

daily use.

I am sensible that I am treading on delicate ground, but I am

determined to speak my sentiments with plainness and sincerity, since

the health and welfare of thousands are concerned. Most persons have

so indulged themselves in this pernicious habit of drinking wine,

that they imagine they cannot live without a little every day; they

think that their very existence depends upon it, and that their

stomachs require it. Similar arguments may be brought in favour of

every other bad habit. Though, at first, the violence we do to nature

makes her revolt; in a little time she submits, and is not only

reconciled, but grows fond of the habit; and we think it necessary to

our existence: neither the flavour of wine, of opium, of snuff, or of

tobacco, are naturally agreeable to us: on the contrary, they are

highly unpleasant at first; but by the force of habit they become

pleasant.

It is, however, the business of rational beings to distinguish

carefully, between the real wants of nature, and the artificial calls

of habit; and when we find that the last begin to injure us, we ought

to use the most persevering efforts to break the enchantment of bad

customs; and though it cost us some uneasy sensations at first, we

must learn to bear them patiently; a little time will reward us for

our forbearance, by a reestablishment of health and spirits.

I shall now proceed to examine the opposite class of nervous

complaints: or such as do really depend on debility, or an asthenic

state of the system. These may be divided into two orders; viz. those

of direct, and those of indirect debility. I shall first consider

those of direct debility.

Though these complaints originate from a deficiency of stimulus, yet

it is very seldom from a deficiency of the common stimulant powers.

The only people, who in general labour under this deficiency of the

common stimulants, are the poor; they are seldom troubled with

nervous complaints; their daily exercise, and constant attention to

procure common necessaries, prevent their feeling what so grievously

afflicts the rich and luxurious. These complaints arise chiefly from

a deficiency of mental stimuli. The most common cause of them, and

whose effects are the most difficult to remove, is to be looked for

in the mind.

The passions and emotions, when exercised with moderation, and kept

within proper bounds, are the sources of life and activity; without

these precious affections, we should be reduced to a kind of

vegetation, equally removed from pleasure and from pain. For want of

these elastic springs, the animal spirits lose their regularity and

play; life becomes a lethargic sleep, and we fall into indifference

and languor.

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