We have now seen how the process of digestion is performed, at least,

so far as we are acquainted with it, and how its products are

conveyed into the blood. But to what purposes the blood is employed,

which is formed with so much care, we have yet to discover. It seems

to answer two purposes. The parts of which the body is composed,

namely, bones, muscles, ligaments, membranes, &c. are continually

changing: in youth they are increasing in size and strength, and in

mature age they are continually acting, and, consequently,

continually liable to waste and decay. They are often exposed to

accidents, which render them unfit for performing their various

functions; and even when no such accidents happen, it seems necessary

for the health of the system that they should be perpetually renewed.

Materials must therefore be provided for repairing, increasing, or

renewing all the various organs of the body. The bones require

phosphate of lime, and gelatine, the muscles fibrine, and the

cartilages and membranes albumen; and accordingly we find all these

substances contained in the blood, from whence they are drawn, as

from a storehouse, whenever they are wanted. The process by which

these different parts of the blood become various parts of the body

is called assimilation.

Over the nature of assimilation the thickest darkness still hangs;

all that we know for certain is, that there are some conditions

necessary to its action, without which it cannot take place. These

are, 1. A sound and uninterrupted state of the nerves. 2. A sound

state of the blood vessels. 3. A certain degree of tone or vigour in

the vessels of the part.

There remains yet to be noticed another set of vessels, connected

with the circulating and nutritive systems, called lymphatics. These

vessels are very minute, and filled with a transparent fluid: they

rise by open mouths in every cavity of the body, as well as from

every part of the surface, and the course of those from the lower

extremities, and indeed from most of the lower parts of the body, is

towards the thoracic duct, which they enter at the same time with the

lacteal vessels already described. They are furnished, like the

lacteals, with numerous valves, which prevent their contents from

returning towards their extremities.

The minute arteries in every part of the body exhale a colourless

fluid, for lubricating the different parts, and other important

purposes: and the lymphatic vessels absorb the superfluous quantity

of this fluid, and convey it back to the blood.

It must be evident therefore, that, if the lymphatics in any cavity

become debilitated, or by any other means be prevented from absorbing

this exhaled fluid, an accumulation of it will take place: the same

will happen, if the exhaling arteries be debilitated, so as to allow

a greater quantity of fluid to escape than the absorbents can take

up. When the balance between exhalation and absorption is destroyed,

by either or both of these means, a dropsy will be the consequence.

Before we finish the subject of digestion, I shall take a short view

of some of the morbid affections, attending this important function

of the animal economy.

A deficiency of appetite may arise, either from an affection of the

stomach, or a morbid state of the body: for there is such a sympathy

between the stomach and the rest of the system, that the first is

very seldom disordered, without communicating more or less disorder

to the system: nor can the system become deranged and the stomach

remain sound.

A want of appetite may arise from overloading the stomach, whereby

its digestive powers will be weakened. And this may be occasioned in

two ways. First, by taking food of the common quality in too great

quantity, which will certainly weaken the powers of the stomach. An

excellent rule, and one which if more attended to, would prevent the

dreadful consequences of indigestion, is always to rise from the

table with some remains of appetite. This is a rule applicable to

every constitution, but particularly to the sedentary and

debilitated.

The second way in which the stomach may be debilitated, is by taking

food too highly stimulating or seasoned; and this even produces much

worse effects than an over dose with respect to quantity. The tone of

the stomach is destroyed, and a crude unassimilated chyle is absorbed

by the lacteals, and carried into the blood, contaminating its whole

mass. Made dishes, enriched with hot sauces, stimulate infinitely

more than plain food, and bring on diseases of the worst kind: such

as gout, apoplexy, and paralysis. "For my part," says an elegant

writer, "when I behold a fashionable table set out in all its

magnificence, I fancy I see gouts, and dropsies, fevers, and

lethargies, with other innumerable distempers, lying in ambuscade

among the dishes."

All times of the day are not equally fitted for the reception of

nourishment. That digestion may be well performed, the functions of

the stomach and of the body must be in full vigour. The early part of

the day therefore is the proper time for taking nutriment; and, in my

opinion, the principal meal should not be taken after two or three

o'clock, and there should always be a sufficient time between each

meal to enable the stomach to digest its contents. I need not remark

how very different this is from the common practice of jumbling two

or three meals together, and at a time of the day likewise when the

system is overloaded. The breakfast at sunrise, the noontide repast

and the twilight pillow, which distinguished the days of Elizabeth,

are now changed for the evening breakfast, and the midnight dinner.

The evening is by no means the proper time to take much nourishment:

for the powers of the system, and particularly of the stomach, are

then almost exhausted, and the food will be but half digested.

Besides, the addition of fresh chyle to the blood, together with the

stimulus of food acting on the stomach, always prevents sleep, or

renders it confused and disturbed, and instead of having our worn out

spirits recruited, by what is emphatically called by Shakespeare,

"the chief nourisher in life's feast," and rising in the morning

fresh and vigorous, we become heavy and stupid, and feel the whole

system relaxed.

It is by no means uncommon, for a physician to have patients, chiefly

among people of fashion and fortune, who complain of being hot and

restless all night, and having a bad taste in the mouth in the

morning. On examination, I have found that, at least in nineteen

cases out of twenty, this has arisen from their having overloaded

their stomachs, and particularly from eating hot suppers; nor do I

recollect a single instance of a complaint of this kind in any person

not in the habit of eating such suppers.

The immoderate use of spirituous and fermented liquors, is still more

destructive of the digestive powers of the stomach; but this will be

better understood, when we have examined the laws by which external

powers act upon the body. The remarks I have made could not, however,

I think, have come in better, than immediately after our examination

of the structure of the digestive organs, as the impropriety of

intemperance, with respect to food, is thus rendered more evident.

The appetite becomes deficient from want of exercise, independently

of the other causes that have been mentioned. Of all the various

modes of preserving health, and preventing diseases, there is none

more efficacious than exercise; it quickens the motion of the fluids,

strengthens the solids, causes a more perfect sanguification in the

lungs, and, in short, gives strength and vigour to every function of

the body. Hence it is, that the Author of nature has made exercise

absolutely necessary to the greater part of mankind for obtaining

means of existence. Had not exercise been absolutely necessary for

our well being, says the elegant Addison, nature would not have made

the body so proper for it, by giving such an activity to the limbs,

and such a pliancy to every part, as necessarily produce those

compressions, extensions, contortions, dilatations, and all other

kinds of motion, as are necessary for the preservation of such a

system of tubes and glands.

We may, indeed, observe, that nature has never given limbs to any

animal, without intending that they should be used. To fish she has

given fins, and to the fowls of the air wings, which are incessantly

used in swimming and flying; and if she had destined mankind to be

eternally dragged about by horses, her provident economy would surely

have denied them legs.

The appetite becomes deficient on the commencement of many diseases,

but this is to be looked upon here rather as a salutary than as a

morbid symptom, and as a proof that nature refuses the load, which

she can neither digest nor bear with impunity.

In healthy people the appetite is various, some requiring more food

than others; but it sometimes becomes praeternaturally great, and

then may be regarded as a morbid symptom. The appetite may be

praeternaturally increased, either by an unusual secretion of the

gastric juice, which acts upon the coats of the stomach, or by any

acrimony, either generated in, or received into the stomach, or,

lastly, by habit, for people undoubtedly may gradually accustom

themselves to take more food than is necessary.

The appetite sometimes becomes depraved, and a person thus affected,

feels a desire to eat substances that are by no means nutritious, or

even esculent: this often depends on a debilitated state of the whole

system. There are some instances, however, in which this depravity of

the appetite is salutary; for example, the great desire which some

persons, whose stomachs abound with acid, have for eating chalk, and

other absorbent earths: likewise, the desire which scorbutic patients

have for grass, and other fresh vegetables. Appetites of this kind,

if moderately indulged in, are salutary, rather than hurtful.

The appetite for liquids as well as solids is sometimes observed to

be deficient, and sometimes too great. The former can scarcely be

considered as a morbid symptom, provided the digestion and health be

otherwise good. But when along with diminished thirst, the fauces and

tongue are dry, this deficiency may be regarded as a morbid and

dangerous symptom.

A more common morbid symptom, however, is too great thirst, which may

arise from a deficiency of fluids in the body, produced by violent

exercise, perspiration, too great a flow of urine, or too great an

evacuation of the intestines. A praeternatural thirst may likewise

arise from any acrid substance received into the stomach, which our

provident mother, nature, teaches us to correct by dilution; this is

the case with respect to salted meats, or those highly seasoned with

pepper. It may arise also from the stomach being overloaded with

unconcocted aliment, or from a suppressed or diminished secretion of

the salivary liquors in the mouth, which may arise from fever, spasm,

or affections of the mind; an increased thirst may likewise take

place, from a derivation or determination of the fluids to other

parts of the body; of this, dropsy affords an example. Indeed,

various causes may concur to increase the thirst; this is the case in

most fevers, where great thirst is occasioned by the dissipation of

the fluids of the body by heat, as well as by the diminished

secretion of the salivary humours which should moisten the mouth; to

which may be added, the heat and diminished concoctive powers of the

stomach.

From what has been said, we can easily understand, why praeternatural

thirst may sometimes be a necessary instinct of nature, at other

times, an unnecessary craving; why acids, acescent fruits, and weak

fermented liquors quench thirst more powerfully than pure water; and

lastly, why thirst, in some instances, may be relieved by emetics,

when it has resisted other remedies.

There is no organ of the body whose functions are so easily deranged

as those of the stomach; and these derangements prove a very fertile

source of disease; they ought, therefore, carefully to be guarded

against; and it is fortunate for us that we have this generally in

our power, if we would but avail ourselves of it: for most of the

derangements proceed from the improper use of food and drink, and a

neglect of exercise. Indeed, when we examine, we shall find but a

short list in the long catalogue of human diseases, which it is not

in our power to guard against and prevent: and which surely will be

guarded against, when their causes are known, and consequences

understood.

Among the diseases arising from a disordered state of the stomach and

indigestion, may be enumerated the following: great oppression and

anxiety, pain in the region of the stomach, with acid eructations,

nausea, vomiting, the bowels sometimes costive, sometimes too loose,

but seldom regular, depression of spirits, and all the long list,

commonly, but very improperly, termed nervous complaints, deficient

nutrition, and consequently general weakness, a relaxed state of the

solids, too great a tenuity of the fluids, headach, vertigo, and

many other complaints, too numerous to mention here.

The greatest misfortune, and which indeed arises from a want of

physiological knowledge, is, that people labouring under these

disorders, imagine they may be cured by the reception of drugs into

the stomach, and thus they are induced to receive into that organ,

half the contents of an apothecary's shop. There is no doubt that

these complaints may oftentimes be alleviated, and the cure assisted,

by medicines: thus, when the stomach is overloaded, this may be

removed by an emetic; the same complaint of the bowels may be removed

by a cathartic; and when the stomach is debilitated, we are

acquainted with some substances which will give it vigour, such as

iron, the Peruvian bark, and several kinds of bitters. These however,

when used alone, afford but temporary relief; and unless the cause

which induced the disease be removed, it will afterwards return with

redoubled violence. When the stomach, for instance, is debilitated by

want of exercise, I would ask, is there an article in the whole

materia medica, that can cure the complaints of sedentary people,

unless proper exercise at the same time be taken? With exercise tonic

remedies will undoubtedly accelerate the cure, but without it, they

will only make bad worse.

Again, when the stomach is debilitated by the use of improper food,

or the abuse of fermented or spirituous liquors, I would say to any

one who pretended to cure me of these complaints, without my making a

total change in the manner of living, that he either was ignorant of

the matter, or intended to deceive me.

In many cases the change of food must be strictly observed and

persevered in for a long time before a cure can be effected. In some

instances where the powers of the stomach were too weak to prevent

the food from undergoing perhaps both a vinous and acetous

fermentation, and where, in consequence of the disengagement of gas

and the formation of acid, the most excruciating pains were felt, the

most dreadful sickness experienced, and all the symptoms of

indigestion present in the most aggravated state; after almost every

article in the materia medica, generally employed, had been tried

without success, I have cured the patient merely by prohibiting food

subject to fermentation, such as vegetables, and enjoining a strict

use of animal food alone.

In short, wherever the cause of a disease can be ascertained, the

grand and simple secret in the cure, is the careful removal of that

cause.

LECTURE V.

OF THE SENSES IN GENERAL.

In this lecture, I propose to take a view of the connexion of man

with the external world, and shall endeavour to point out the manner

in which he becomes acquainted with external objects, by means of the

faculties called senses.

A human creature is an animal endowed with understanding, and reason;

a being composed of an organized body, and a rational mind.

With respect to his body, he is pretty similar to other animals,

having similar organs, powers, and wants. All animals have a body

composed of several parts, and, though these may differ from the

structure of the human body in some circumstances, to accommodate it

to peculiar habits and wants of the animal, still there is a great

similarity in the general structure.

The human body is feeble at its commencement, increases gradually in

its progress by the help of nourishment and exercise, till it arrives

at a certain period, when it appears in full vigour; from this time

it insensibly declines to old age, which conducts it at length to

dissolution. This is the ordinary course of human life, unless it

happens to be abridged either by disease or accident.

With regard to his reasoning faculties, or mind, man is eminently

distinguished from other animals. It is by this noble part that he

thinks, and is capable of forming just ideas of the different objects

that surround him: of comparing them together; of inferring from

known principles unknown truths; of passing a solid judgment on the

mutual agreement of things, as well as on the relations they bear to

him; of deliberating on what is proper or improper to be done; and of

determining how to act. The mind recollects what is past, joins it

with the present, and extends its views to futurity. It is capable of

penetrating into the causes of events, and discovering the connexion

that exists between them.

Governed by invariable laws, which connect him with all the beings,

whether animate or inanimate, among which he exists, man has certain

relations of convenience, and inconvenience, arising from the

particular constitution of the surrounding objects, as well as of his

own body. These external objects possess qualities which may be

useful or prejudicial to him; and his interest requires, that he

should be capable of ascertaining and appreciating these properties.

It is by sensation, or feeling, that the knowledge of external

objects is obtained. The faculty of feeling, modified in every organ,

perceives those qualities for which the peculiar structure of the

organ is fitted; and all the various sensations of sound, colour,

taste, smell, resistance, and temperature, find appropriate organs by

which they are perceived, without mixing with, or confounding each

other. External objects, therefore, act upon the parts of the body

endowed with feeling, and their action is diversified in such a

manner, as to give us a great number of sensations, which appear to

have no resemblance to each other, and which make us acquainted with

the various properties of surrounding objects.

It would not, however, have been sufficient for man, merely to have

possessed this power of perceiving the different properties of the

objects which surround him: it was necessary likewise, that he should

be possessed of motion, that he might be able to approach or avoid

them, to seize or repulse them, as it suited his convenience or

advantage. By the extreme mobility of his limbs, he is able to move

his body, and transport it from place to place; to bring external

objects nearer to him, to remove them to a greater distance, and to

place them in such situations and such circumstances, as may enable

them to act on each other, and produce the changes which he wishes.

The human body, therefore, may be regarded as a machine composed

(besides the moving parts which have formerly been noticed) of divers

organs upon which external objects act, and produce those impressions

which convince us of their presence, and make us acquainted with

their properties. These impressions are transmitted to the sentient

principle, or mind; and the faculty we possess of perceiving these

impressions has been called by physiologists, sensibility.

Sensation has generally been defined by metaphysicians to be a change

in the mind, of which we are conscious, caused by a correspondent

change in the state of the body. This definition, however, leaves the

matter where they found it, and throws no light whatever on the

nature of sensation; nor can we say any thing more concerning it,

than that, when the organs are in a sound state, certain sensations

are perceived, which force us to believe in the existence of external

objects, though there is no similarity whatever, nor any necessary

connexion, that we can perceive, between the sensation and the object

which caused it.

All the different degrees of sensation may be reduced to two kinds:

pleasant and painful. The nature of these two primitive modes of

sensation, is as little known to us as their different species: all

that can be said, is, that the general laws by which the body is

governed, are such, that pleasure is generally connected with those

impressions which tend to its preservation, and pain with those which

cause its destruction.

In a general point of view, sensibility may be regarded as an

essential property of every part of the living body, disposing each

part to perform those functions, the object of which is to preserve

the life of the animal. Sensibility presides over the most necessary

functions, and watches carefully over the health of the body: she

directs the choice of the air proper for respiration, and also of

alimentary substances; the mechanism of the secretions is likewise

placed under her power; and in the same way that the eye perceives

colours, and the ear sounds, so every animated and living part is

fitted to receive impressions from the objects appropriated to it.

That every part of the animal is endowed with sensibility, is evident

from a variety of facts, particularly from the action which follows

when a muscle taken out of the animal body is irritated by any

stimulus: this is evident, by a variety of facts mentioned by Whytt,

Boerhaave, and others, which show, that parts recently taken from the

animal body retain a portion of sensibility, which continues to

animate them, and render them capable of action for a considerable

time.

The primary organ of sensation appears to be the brain, its

continuation in the form of medulla oblongata and spinal marrow, and

the various nerves proceeding from these; and it seems now generally

agreed, that unless there be a free communication of nerves between

the part where the impression is made, and the brain, no sensation

will take place; for instance, if the nerves be cut or compressed.

In a sound body, sensation is caused, whenever a change takes place

in the state of the nervous power, whether that change be produced by

an external, or an internal cause. The former kind of sensation is

said to arise from impression or impulse, the latter from

consciousness.

Every impression or impulse is not, however, equally calculated to

produce sensation; for this purpose, a middle degree of impulse

appears the best. An impulse considerably less produces no sensation,

and one more violent may cause pain, but no proper sensation denoting

the presence or properties of external objects. Thus too small a

degree of light makes no impression on the optic nerve; and if the

object be too strongly illuminated, the eye is pained, but has no

proper idea of the figure or colour of the object. In the same way,

if the vibrations which give us an idea of sound, be either too quick

or too slow, we shall not obtain this idea. When the vibration is too

quick, a very disagreeable and irritating sensation is perceived, as

for instance, in the whetting of a saw: and on the other hand, when

the vibrations are too slow, they will not produce a tone or sound.

This might be proved of all the senses, and shows, that a certain

degree of impression is necessary to produce perfect sensation.

There is another circumstance likewise requisite to produce

sensation: it is not enough, that the impression should be of the

proper strength; it is necessary likewise, that it should remain for

some time, otherwise no sensation will be produced. There are many

bodies whose magnitude is amply sufficient to be perceived by the

eye; yet, by reason of their great velocity, the impulse they make on

any part of the retina is so short, that they are not visible. This

is proved by our not perceiving the motions of cannon and musket

balls, and many other kinds of motion. On this principle depends the

art of conjuration, or legerdemain; the fundamental maxim of those

who practise them, is, that the motion is too quick for sight.

If the impulse be of a proper degree, and be continued for a

sufficient length of time, the impression made by it will not

immediately vanish with the impulse which caused it, but will remain

for a time proportioned to the strength of the impulse. This, with

respect to sight, is proved by whirling a firebrand in a circular

manner, by which the impression of a circle is caused, instead of a

moving point: and, with respect to hearing, it may be observed, that

when children run with a stick quickly along railing, or when a drum

is beaten quickly, the idea of a continued sound is produced, because

the impression remains some time: for it is evident, that the sounds

produced in succession are perfectly distinct and insulated.

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