This drug, first brought into prominence as a cure for snake bite among

the Indians, is now employed as an expectorant, emetic, and diuretic. It

is official in the Pharmacopœia of the United States.

STILLINGIA.

_Stillingia sylvatica_ L.

_Pharmacopœial name._—Stillingia.

_Other common names._—Queen’s-delight, queen’s-root, silverleaf,

nettle-potato.

_Habitat and range._—This plant is found in dry, sandy soil and in pine

barrens from Maryland to Florida west to Kansas and Texas.

[Illustration: FIG. 19.—Stillingia (_Stillingia sylvatica_), upper

portion of plant and part of spike showing male flowers. (After Bentley

and Trimen, Medicinal Plants.)]

_Description of plant._—Like most of the other members of the spurge

family (Euphorbiaceæ) stillingia also contains a milky juice. This

indigenous, herbaceous perennial is about 1 to 3 feet in height, bright

green and somewhat fleshy, with crowded leaves of a somewhat leathery

texture. The leaves are practically stemless and vary greatly in form,

from lance shaped, oblong, to oval and elliptical, round toothed or saw

toothed. The pale-yellow flowers, which appear from April to October,

are borne in a dense terminal spike and consist of two kinds, male and

female, the male flowers arranged in dense clusters around the upper

part of the stalk and the female flowers occurring at the base of the

spike. (Fig. 19.) The seeds are contained in a roundish 3-lobed capsule.

_Description of root._—Stillingia consists of somewhat cylindrical or

slenderly spindle-shaped roots from 6 inches to a foot in length,

slightly branched, the yellowish white, porous wood covered with a

rather thick, reddish brown, wrinkled bark, the whole breaking with a

fibrous fracture. As found in commerce, stillingia is usually in short

transverse sections, the ends of the sections pinkish and fuzzy with

numerous fine, silky bast fibers, and the bark showing scattered

yellowish brown resin cells and milk ducts. It has a peculiar unpleasant

odor, and a bitter, acrid, and pungent taste.

_Collection, prices, and uses._—Stillingia root is collected late in

autumn or early in spring, usually cut into short, transverse sections

and dried. The price ranges from 3 to 5 cents a pound.

This root, which is official in the United States Pharmacopœia, has been

a popular drug in the South for more than a century, and is employed

principally as an alterative.

WILD SARSAPARILLA.

_Aralia nudicaulis_ L.

_Other common names._—False sarsaparilla, Virginian sarsaparilla,

American sarsaparilla, small spikenard, rabbit’s-root, shotbush, wild

licorice.

_Habitat and range._—Wild sarsaparilla grows in rich, moist woods from

Newfoundland west to Manitoba and south to North Carolina and Missouri.

_Description of plant._—This native herbaceous perennial, belonging to

the ginseng family (Araliaceæ), produces a single, long-stalked leaf and

flowering stalk from a very short stem, both surrounded or sheathed at

the base by thin, dry scales. The leafstalk is about 12 inches long,

divided at the top into three parts, each division bearing five oval,

toothed leaflets from 2 to 5 inches long, the veins on the lower surface

sometimes hairy.

The naked flowering stalk bears three spreading clusters of small,

greenish flowers, each cluster consisting of from 12 to 30 flowers,

produced from May to June, followed later in the season by purplish

black roundish berries, about the size of the common elderberries. (Pl.

V, fig. 2.)

_Description of rootstock._—Wild sarsaparilla rootstock has a very

fragrant, aromatic odor. Rabbits are said to be very fond of it, whence

one of the common names, “rabbit’s-root,” is derived. The rootstock is

rather long, horizontally creeping, somewhat twisted, and yellowish

brown on the outside. (Pl. V, fig. 2.) The taste is warm and aromatic.

The dried rootstock is brownish gray and wrinkled lengthwise on the

outside, about one-fourth of an inch in thickness, the inside whitish

with a spongy pith. The taste is sweetish and somewhat aromatic.

_Collection, prices, and uses._—The root of wild sarsaparilla is

collected in autumn, and brings from 5 to 8 cents a pound.

This has long been a popular remedy, both among the Indians and in

domestic practice, and was official in the United States Pharmacopœia

from 1820 to 1880. Its use is that of an alterative, stimulant, and

diaphoretic, and in this it resembles the official sarsaparilla obtained

from tropical America.

_Similar species._—The American spikenard (_Aralia racemosa_ L.), known

also as spignet, spiceberry, Indian-root, petty-morrel, life-of-man, and

old-man’s-root, is employed like _Aralia nudicaulis_. It is

distinguished from this by its taller, herbaceous habit, its

much-branched stem from 3 to 6 feet high, and very large leaves

consisting of thin, oval, heart-shaped, double saw-toothed leaflets. The

small greenish flowers are arranged in numerous clusters, instead of

only three as in _nudicaulis_, and also appear somewhat later, namely,

from July to August. The berries are roundish, reddish brown, or dark

purple.

The rootstock is shorter than that of _nudicaulis_, and much thicker,

with prominent stem scars, and furnished with numerous, very long,

rather thick roots. The odor and taste are stronger than in

_nudicaulis_. It is also collected in autumn, and brings from 4 to 8

cents a pound.

The American spikenard occurs in similar situations as _nudicaulis_, but

its range extends somewhat farther south, Georgia being given as the

southern limit.

The California spikenard (_Aralia californica_ Wats.) may be used for

the same purposes as the other species. The plant is larger than _Aralia

racemosa_, but otherwise is very much like it. The root is also larger

than that of _A. racemosa_.

GINSENG.

_Panax quinquefolium_ L.

_Other common names._—American ginseng, sang, red-berry, five-fingers.

(Pl. V, fig. 3.)

_Habitat and range._— Ginseng is a native of this country, its favorite

haunts being the rich, moist soil in hardwood forests from Maine to

Minnesota southward to the mountains of northern Georgia and Arkansas.

For some years ginseng has been cultivated in small areas from central

New York to Missouri.

_Description of plant._—Ginseng is an erect perennial plant growing from

8 to 15 inches in height, and bearing three leaves at the summit, each

leaf consisting of five thin, stalked, ovate leaflets, long pointed at

the apex, rounded or narrowed at the base, the margins toothed; the

three upper leaflets are largest and the two lower ones smaller. From 6

to 20 greenish yellow flowers are produced in a cluster during July and

August, followed later in the season by bright crimson berries. It

belongs to the ginseng family (Araliaceæ).

_Description of root._—Ginseng has a thick, spindle-shaped root, 2 to 3

inches long or more, and about one-half to 1 inch in thickness, often

branched, the outside prominently marked with circles or wrinkles. (Pl.

V, fig. 3.) The spindle-shaped root is simple at first, but after the

second year it usually becomes forked or branched, and it is the

branched root, especially if it resembles the human form, that finds

particular favor in the eyes of the Chinese, who are the principal

consumers of this root.

Ginseng root has a thick, pale yellowish white or brownish yellow bark,

prominently marked with transverse wrinkles, the whole root fleshy and

somewhat flexible. If properly dried, it is solid and firm. Ginseng has

a slight aromatic odor, and the taste is sweetish and mucilaginous.

_Collection and uses._—The proper time for digging ginseng root is in

autumn, and it should be carefully washed, sorted, and dried. If

collected at any other season of the year, it will shrink more and not

have the fine plump appearance of the fall-dug root.

The National Dispensatory contains an interesting item concerning the

collection of the root by the Indians. They gather the root only after

the fruit has ripened, and it is said that they bend down the stem of

ripened fruit before digging the root, covering the fruit with earth,

and thus providing for future propagation. The Indians claim that a

large percentage of the seeds treated in this way will germinate.

Although once official in the United States Pharmacopœia, from 1840 to

1880, it is but little used medicinally in this country except by the

Chinese residents, most of the ginseng produced in this country being

exported to China. The Chinese regard ginseng root as a panacea. It is

on account of its commercial prominence that it is included in this

paper.

_Cultivation._—There is probably no plant that has become better known,

at least by name, during the past ten years or more than ginseng. It has

been heralded from north to south and east to west as a money-making

crop. The prospective ginseng grower must not fail to bear in mind,

however, that financial returns are by no means immediate. Special

conditions and unusual care are required in ginseng cultivation,

diseases must be contended with, and a long period of waiting is in

store for him before he can realize on his crop.

Either roots or seeds may be planted, and the best success with ginseng

is obtained by following as closely as possible the conditions of its

native habitat. Ginseng needs a deep, rich soil, and, being a plant

accustomed to the shade of forest trees, will require shade, which can

be supplied by the erection of lath sheds over the beds. A heavy mulch

of leaves or similar well-rotted vegetable material should be applied to

the beds in autumn.

If roots are planted, they are set in rows about 8 inches apart and 8

inches apart in the row. In this way a marketable product will be

obtained sooner than if grown from seed. The seed is sown in spring or

autumn in drills 6 inches apart and about 2 inches apart in the row. The

plants remain in the seed bed for two years and are then transplanted,

being set about 8 by 8 inches apart. It requires from five to seven

years to obtain a marketable crop from the seed. Seed intended for

sowing should not be allowed to dry out, as this is supposed to destroy

its vitality.

_Price._—The price of wild ginseng roots ranges from $5 a pound upward.

The cultivated root generally brings a lower price than the wild root,

and southern ginseng roots are worth less than those from northern

localities.

_Exports._—The exports of ginseng for the year ended June 30, 1906,

amounted to 160,949 pounds, valued at $1,175,844.

WATER-ERYNGO.

_Eryngium yuccifolium_ Michx.

_Synonym._—_Eryngium aquaticum_ L.

_Other common names._—Eryngium, eryngo, button-snakeroot,

corn-snakeroot, rattlesnake-master, rattlesnake-weed, rattlesnake-flag.

_Habitat and range._—Although sometimes occurring on dry land,

water-eryngo usually inhabits swamps and low, wet ground, from the pine

barrens of New Jersey westward to Minnesota and south to Texas and

Florida.

_Description of plant._—The leaves of this plant are grasslike in form,

rigid, 1 to 2 feet long, and about one-half inch or a trifle more in

width; they are linear, with parallel veins, pointed, generally clasping

at the base, and the margins bristly with soft, slender spines. The

stout, furrowed stem reaches a height of from 2 to 6 feet, and is

generally unbranched except near the top. The insignificant whitish

flowers are borne in dense, ovate-globular, stout-stemmed heads,

appearing from June to September, and the seed heads that follow are

ovate and scaly. (Pl. V, fig. 4.) Water-eryngo belongs to the parsley

family (Apiaceæ) and is native in this country.

_Description of rootstock._—The stout rootstock is very knotty, with

numerous short branches, and produces many thick, rather straight roots

(Pl. V, fig. 4), both rootstock and roots of a dark-brown color, the

latter wrinkled lengthwise. The inside of the rootstock is yellowish

white. Water-eryngo has a somewhat peculiar, slightly aromatic odor, and

a sweetish, mucilaginous taste at first, followed by some bitterness and

pungency.

_Collection, prices, and uses._—The root of this plant is collected in

autumn and brings from 5 to 10 cents a pound.

Water-eryngo is an old remedy, and one of its early uses, as the several

common names indicate, was for the treatment of snake bites. It was

official in the United States Pharmacopœia from 1820 to 1860, and is

employed now as a diuretic and expectorant, and for promoting

perspiration. In large doses it acts as an emetic, and the root, when

chewed, excites a flow of saliva. It is said to resemble Seneca

snakeroot in action.

AMERICAN ANGELICA.

_Angelica atropurpurea_ L.

_Synonym._—_Archangelica atropurpurea_ Hoffm.

_Other common names._—Angelica, purple-stemmed angelica, great angelica,

high angelica, purple angelica, masterwort.

_Habitat and range._—American angelica is a native herb, common in

swamps and damp places from Labrador to Delaware and west to Minnesota.

_Description of plant._—This strong-scented, tall, stout perennial

reaches a height of from 4 to 6 feet, with a smooth, dark-purple, hollow

stem 1 to 2 inches in diameter. The leaves are divided into three parts,

each of which is again divided into threes; the rather thin segments are

oval or ovate, somewhat acute, sharply toothed and sometimes deeply cut,

and about 2 inches long. The lower leaves sometimes measure 2 feet in

width, while the upper ones are smaller, but all have very broad

expanded stalks. The greenish white flowers are produced from June to

July in somewhat roundish, many-rayed umbels or heads, which sometimes

are 8 to 10 inches in diameter. The fruits are smooth, compressed, and

broadly oval. (Pl. VI, fig. 1.) American angelica belongs to the parsley

family (Apiaceæ).

_Description of root._—American angelica root is branched, from 3 to 6

inches long, and less than an inch in diameter. The outside is light

brownish gray, with deep furrows, and the inside nearly white, the whole

breaking with a short fracture and the thick bark showing fine resin

dots. It has an aromatic odor, and the taste at first is sweetish and

spicy, afterwards bitter. The fresh root is said to possess poisonous

properties.

The root of the European or garden angelica (_Angelica officinalis_

Moench) supplies much of the angelica root of commerce. This is native

in northern Europe and is very widely cultivated, especially in Germany,

for the root.

_Collection, prices, and uses._—The root is dug in autumn and carefully

dried. Care is also necessary in preserving the root, as it is very

liable to the attacks of insects. American angelica root ranges from 6

to 10 cents a pound.

American angelica root, which was official in the United States

Pharmacopœia from 1820 to 1860, is used as an aromatic, tonic,

stimulant, carminative, diuretic, and diaphoretic. In large doses it

acts as an emetic.

The seeds are also employed medicinally.

YELLOW JASMINE OR JESSAMINE.

_Gelsemium sempervirens_ (L.) Ait. f.

_Pharmacopœial name._—Gelsemium.

_Other common names._—Carolina jasmine or jessamine, Carolina wild

woodbine, evening trumpet-flower.

_Habitat and range._—Yellow jasmine is a plant native to the South,

found along banks of streams, in woods, lowlands, and thickets,

generally near the coast, from the eastern part of Virginia to Florida

and Texas, south to Mexico and Guatemala.

_Description of plant._—This highly ornamental climbing or trailing

plant is abundantly met with in the woods of the Southern States, its

slender stems festooned over trees and fences and making its presence

known by the delightful perfume exhaled by its flowers, filling the air

with a fragrance that is almost overpowering wherever the yellow jasmine

is very abundant.

The smooth shining stems of this beautiful vine sometimes reach a length

of 20 feet. The leaves are evergreen, lance shaped, entire, 1½ to 3

inches long, rather narrow, borne on short stems, and generally

remaining on the vine during the winter. The flowers, which appear from

January to April, are bright yellow, about 1 to 1½ inches long, the

corolla funnel shaped. (Fig. 20.) They are very fragrant, but poisonous,

and it is stated that the eating of honey derived from jasmine flowers

has brought about fatal results.

Yellow jasmine is a perennial, and belongs to a family that is noted for

its poisonous properties, namely, the Logania family (Loganiaceæ), which

numbers among its members such powerful poisonous agents as the

strychnine-producing tree.

_Description of rootstock._—The rootstock of the yellow jasmine is

horizontal and runs near the surface of the ground, attaining great

length, 15 feet or more; it is branched, and here and there produces

fibrous rootlets. When freshly removed from the ground it is very

yellow, with a peculiar odor and bitter taste. For the drug trade it is

generally cut into pieces varying from 1 inch to 6 inches in length, and

when dried consists of cylindrical sections about 1 inch in thickness,

the roots, of course, thinner. The bark is thin, yellowish brown, with

fine silky bast fibers, and the wood is tough and pale yellow, breaking

with a splintery fracture and showing numerous fine rays radiating from

a small central pith. Yellow jasmine has a bitter taste and a pronounced

heavy odor.

[Illustration: FIG. 20.—Yellow jasmine (_Gelsemium sempervirens_).]

_Collection, prices, and uses._—The root of yellow jasmine is usually

collected just after the plant has come into flower and is cut into

pieces from 1 to 6 inches long. It is often adulterated with portions of

the stems, but these can be distinguished by their thinness and dark

purplish color. The prices range from 3 to 5 cents a pound.

Yellow jasmine, which is official in the United States Pharmacopœia, is

used for its powerful effect on the nervous system.

PINKROOT.

_Spigelia marilandica_ L.

_Pharmacopœial name._—Spigelia.

_Other common names._—Carolina pinkroot, Carolina pink, Maryland pink,

Indian pink, starbloom, wormgrass, wormweed, American wormroot.

_Habitat and range._—This pretty little plant is found in rich woods

from New Jersey to Florida, west to Texas and Wisconsin, but occurring

principally in the Southern States. It is fast disappearing, however,

from its native haunts.

_Description of plant._—Pinkroot belongs to the same family as the

yellow jasmine, namely, the Logania family (Loganiaceæ), noted for its

poisonous species. It is a native perennial herb, with simple, erect

stem 6 inches to 1½ feet high, nearly smooth. The leaves are stemless,

generally ovate, pointed at the apex and rounded or narrowed at the

base; they are from 2 to 4 inches long, one-half to 2 inches wide,

smooth on the upper surface, and only slightly hairy on the veins on the

lower surface. The rather showy flowers are produced from May to July in

a terminal one-sided spike; they are from 1 to 2 inches in length,

somewhat tube shaped, narrowed below, slightly inflated toward the

center, and again narrowed or contracted toward the top, and terminating

in five lance-shaped lobes; the flowers are very showy, with their

brilliant coloring—bright scarlet on the outside, and the inside of the

tube and the lobes a bright yellow. The seed capsule is double,

consisting of two globular portions more or less united, and containing

numerous seeds. (Pl. VI, fig. 2.)

_Description of rootstock._—The rootstock is rather small, from 1 to 2

inches in length and about one-sixteenth of an inch in thickness. It is

somewhat crooked or bent, dark brown, with a roughened appearance of the

upper surface caused by cup-shaped scars, the remains of former annual

stems. The lower surface and the sides have numerous long, finely

branched, lighter colored roots, which are rather brittle. Pinkroot has

a pleasant, aromatic odor, and the taste is described as sweetish,

bitter, and pungent.

_Collection, prices, and uses._—Pinkroot is collected after the

flowering period. It is said to be scarce, and was reported as becoming

scarce as long ago as 1830. The price paid to collectors ranges from 25

to 40 cents a pound.

The roots of other plants, notably those of the East Tennessee pinkroot

(_Ruellia ciliosa_ Pursh), are often found mixed with the true pinkroot,

and the _Ruellia ciliosa_ is even substituted for it. This adulteration

or substitution probably accounts for the inertness which has sometimes

been attributed to the true pinkroot and which has caused it to fall

into more or less disuse. It has long been known that the true pinkroot

was adulterated, but this adulteration was supposed to be caused by the

admixture of Carolina phlox (_Phlox carolina_ L., now known as _Phlox

ovata_ L.), but this is said now to be no part of the substitution.[4]

The rootstock of _Ruellia ciliosa_ is larger and not as dark as that of

the Maryland pinkroot and has fewer and coarser roots, from which the

bark readily separates, leaving the whitish wood exposed.

Pinkroot was long known by the Indians, and its properties were made

known to physicians by them. It is official in the United States

Pharmacopœia, and is used principally as an anthelmintic.

AMERICAN COLOMBO.

_Frasera carolinensis_ Walt.

_Synonym._—_Frasera walteri_ Michx.

_Other common names._—Frasera, meadowpride, pyramid-flower,

pyramid-plant, Indian lettuce, yellow gentian, ground-centaury.

_Habitat and range._—American colombo occurs in dry soil from the

western part of New York to Wisconsin, south to Georgia and Kentucky.

_Description of plant._—During the first and second year of the growth

of this plant only the root leaves are produced. These are generally

somewhat rounded at the summit, narrowed toward the base, and larger

than the stem leaves, which develop in the third year. The leaves are

deep green and produced mostly in whorls of four, the stem leaves being

3 to 6 inches in length and oblong or lance shaped. In the third year

the stem is developed and the flowers are produced from June to August.

The stem is stout, erect, cylindrical, and 3 to 8 feet in height. The

flowers of American colombo are borne in large terminal, handsome

pyramidal clusters sometimes 2 feet in length, and are greenish yellow

or yellowish white, dotted with brown purple. They are slender stemmed,

about 1 inch across, with a wheelshaped, 4-parted corolla. The seeds are

contained in a much compressed capsule. (Fig. 21.) American colombo is

an indigenous perennial, and belongs to the gentian family

(Gentianaceæ).

[Illustration: FIG 21.—American colombo (_Frasera carolinensis_),

leaves, flowers, and seed pods.]

_Description of root._—The root is long, horizontal, spindle shaped,

yellow, and wrinkled. In the fresh state it is fleshy and quite heavy.

The American colombo root of commerce, formerly in transverse slices,

now generally occurs in lengthwise slices. The outside is yellowish or

pale orange and the inside spongy and pale yellow. The taste is bitter.

American colombo root resembles the official gentian root in taste and

odor, and the uses are also similar.

_Collection, prices, and uses._—The proper time for collecting American

colombo root is in the autumn of the second year or in March or April of

the third year. It is generally cut into lengthwise slices before

drying. The price of American colombo root ranges from 3 to 5 cents a

pound.

The dried root, which was official in the United States Pharmacopœia

from 1820 to 1880, is used as a simple tonic. In the fresh state the

root possesses emetic and cathartic properties.

BLACK INDIAN HEMP.

_Apocynum cannabinum_ L.

_Pharmacopœial name._—Apocynum.

_Other common names._—Canadian hemp, American hemp, amy-root,

bowman’s-root, bitterroot, Indian-physic, rheumatism-weed, milkweed,

wild cotton, Choctaw-root.

The name “Indian hemp” is often applied to this plant, but it should

never be used without the adjective “black.” “Indian hemp” is a name

that properly belongs to _Cannabis indica_, a true hemp plant, from

which the narcotic drug “hashish” is obtained.

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