But few cases of it came under my care. Having perceived the same

disposition in nature to relieve herself by the pores, that I observed in

the years 1802 and 1803, my remedies were the same as in the latter year,

and attended with the same success. Dr. Caldwell and Dr. Stewart, whose

practice was extensive in Southwark, informed me, those remedies had been

generally successful in their hands.

The only new medicine that the experience of this year suggested in this

disease, was for one of its most distressing and dangerous symptoms, that

is, the vomiting which occurs in its second stage. Dr. Physick

discovered, that ten drops of the spirit of turpentine, given every two

hours, in a little molasses, or syrup, or sweet oil, effectually checked

it in several instances, in patients who afterwards recovered. It was

administered with equal success in a case which came under my care, after

an absence of pulse, and a coldness of the extremities had taken place.

Dr. Church informed me that he gave great relief to the sick in the city

hospital, by this medicine, by prescribing it in glysters, as well as by

the mouth, in distressing affections of the stomach and bowels.

Dr. Stewart observed that all those persons who had been affected by the

yellow fever in former years, had mild remittents in the same situations

that others had the prevailing epidemic in a malignant form.

In one of four bodies the doctor examined, he found six, and in another

three intussusceptions of the intestines, without any signs of

inflammation. He discovered the common marks of disease from this fever

in other parts of those bodies.

The deaths from this fever amounted to between three and four hundred.

They would probably have been more numerous, had not those families who

were in competent circumstances fled into the country, and had not the

poor been removed, by the board of health, from the infected atmosphere

of Southwark, to tents provided for them in the neighbourhood of the

city; and they would probably have been fewer, considering the tractable

nature of the disease, when met by suitable remedies in its early stage,

had not the sick concealed their indisposition, in many instances, for

two or three days, lest they should be dragged to the city hospital, or

have centinels placed at their doors, to prevent any communication with

their friends and neighbours. While these attempts were made to check

the progress of the fever, it did not escape the notice of many of the

citizens of Philadelphia, that not a single instance occurred of its

being communicated by contagion, in any of the families in the city, in

which persons had sickened or died with it, and that while the sick were

deprived of the kind offices of their friends and neighbours, lest they

should be infected, physicians, and the members of the board of health,

passed by the guards every day, in their visits to the same sick people,

and afterwards mixed with their fellow-citizens, in every part of the

city, without changing their clothes.

The yellow fever appeared early in the season in New-Haven, in

Connecticut, and in Providence, on Rhode-Island, in both of which places

it was derived from putrid exhalation, and was speedily and effectually

checked by removing the healthy persons who lived in its neighbourhood to

a distance from it. Several sporadic cases of it occurred during the

autumn in Gloucester county, in New-Jersey, and in Mifflin and Chester

counties, in Pennsylvania. It was epidemic in New-York at the same time

it prevailed in Southwark and Philadelphia. The following extract of a

letter from the health officer of New-York, to one of his friends,

contains a satisfactory proof that it was not, in that city, an imported

disease.

_Quarantine-ground, Sept. 7._

I most sincerely and tenderly deplore the unfortunate situation of our

city. What do people say now of the origin of the disease? You may state,

for the information of those who wished to be informed, that not a single

vessel, on board of which a person has been sick with fever of any kind,

or on board of which any person has died with any disease, while in the

West-Indies, or on the voyage home, has ever gone up to the city during

this whole season. This we know, and this we vouch for; and farther

state, that all the cases of fever that have come down as from the city,

have been _all_ people of, and belonging to the city, and unconnected

with the shipping, excepting one, a sailor, who had no connection with

any foul vessel. There is not a shadow of proof or suspicion that can

attach to the health-office, or to infected vessels, this season.

I am, &c.

JOHN R. B. RODGERS.

Having concluded the history of the bilious yellow fever, as it has

appeared in eleven successive years, since 1793, as an epidemic, or in

sporadic cases, I shall proceed next to enumerate all the sources of

that fever, as well as all the other usual forms of the summer and

autumnal disease of the United States, and afterwards mention the means

of preventing them.

AN INQUIRY

INTO

THE VARIOUS SOURCES

OF THE USUAL FORMS OF

_SUMMER & AUTUMNAL DISEASE_

IN THE UNITED STATES,

AND THE MEANS OF PREVENTING THEM.

The business of the following inquiry is,

I. To enumerate the various sources of the usual forms of the summer and

autumnal disease in the United States. And,

II. To mention the means of preventing them.

To render the application of those means as extensive as possible, it

will be proper to mention, under the first head, all those sources of

summer and autumnal disease, which have been known to produce it in other

countries, as well as in the United States. They are,

1. Exhalations from marshes. These are supposed to be partly of a

vegetable, and partly of an animal nature. They are derived from the

shores of creeks and mill ponds, as well as from low and wet grounds;

also from the following vegetable substances in a state of putrefaction.

2. Cabbage. A malignant fever was produced at Oxford, by a putrid heap of

this vegetable some years ago, which proved fatal to many of the

inhabitants, and to several of the students of the university at that

place.

3. Potatoes. Nearly a whole ship's crew perished at Tortola, by removing

from her hold, a quantity of putrid potatoes.

4. Pepper.

5. Indian meal.

6. Onions.

7. Mint.

8. Anise and caraway seeds, confined in the hold of a ship.

9. Coffee. "About the time," says Dr. Trotter, "when notice was taken of

the putrifying coffee on the wharf at Philadelphia, in the year 1793, a

captain of a man of war, just returned from the Jamaica station, informed

me, that several vessels laden with the same produce came to Kingston,

from St. Domingo. During the distracted state of that colony, this

article, with other productions, had been allowed to spoil and ferment.

The evolution of a great quantity of fixed air, or carbonic acid gas, was

the consequence; and in these vessels, when opening the hatchways, such

was its concentrated state, that the whole of the crew, in some of them,

were found dead on the deck. A pilot boarded one of them in this

condition, and had nearly perished himself[10]."

[10] Medicina Nautica, p. 324.

10. Chocolate shells.

11. Cotton which had been wetted on board of a vessel that arrived in

New-York, a few years ago, from Savannah, in Georgia.

12. Hemp, flax, and straw.

13. The canvas of an old tent.

14. Old books, and old paper money, that had been wetted, and confined in

close rooms and closets.

15. The timber of an old house. A fever produced by this cause is

mentioned by Dr. Haller, in his Bibliotheca Medicinæ.

16. Green wood confined in a close cellar during the summer months. A

fever from this cause was once produced in this city, in a family that

was attended by the late Dr. Cadwallader.

17. The green timber of a new ship. Captain Thomas Bell informed me, that

in a voyage to the East-Indies, in the year 1784, he lost six of his men

with the scurvy, which he supposed to be derived wholly from the foul air

emitted by the green timber of his ship. The hammocks which were near the

sides of the ship rotted during the voyage, while those which were

suspended in the middle of the ship, retained their sound and natural

state. This scurvy has been lately proved by Dr. Claiborne, in an

ingenious inaugural dissertation, published in Philadelphia, in the year

1798, to be a misplaced state of malignant fever. Dr. Lind mentions

likewise the timber of new ships as one of the sources of febrile

diseases. The timber of soldiers' huts, and of the cabins of men who

follow the business of making charcoal in the woods, often produce

fevers, as soon as the bark begins to rot and fall from them, which is

generally on the second year after they are erected. Fevers have been

excited even by the exhalation from trees, that have been killed by being

girdled in an old field.

18. The stagnating air of the hold of a ship.

19. Bilge water.

20. Water that had long been confined in hogsheads at sea.

21. Stagnating rain water.

22. The stagnating air of close cellars.

23. The matters which usually stagnate in the gutters, common sewers,

docks, and alleys of cities, and in the sinks of kitchens. A citizen of

Philadelphia, who had a sink in his kitchen, lost a number of cats and

dogs by convulsions. At length one of his servants was affected with the

same disease. This led him to investigate the cause of it. He soon traced

it to his sink. By altering its construction, so as to prevent the escape

of noxious air from it, he destroyed its unwholesome quality, so that all

his domestics lived in good health in his kitchen-afterwards.

24. Air emitted by agitating foul and stagnating water. Dr. Franklin was

once infected with an intermitting fever from this cause.

25. A duck pond. The children of a family in this city were observed, for

several successive years, to be affected with a bilious remitting fever.

The physician of the family, Dr. Phineas Bond, observing no other persons

to be affected with the same fever in the neighbourhood, suspected that

it arose from some local cause. He examined the yard belonging to the

house, where he found an offensive duck pond. The pond was filled with

earth, and the family were afterwards free from an annual bilious fever.

26. A hog-stye has been known to produce violent bilious fevers

throughout a whole neighbourhood in Philadelphia.

27. Weeds cut down, and exposed to heat and moisture near a house.

Fevers are less frequently produced by putrid animal, than by putrid

vegetable matters. There are, however, instances of their having been

generated by the following animal substances in a state of putrefaction.

1. Human bodies that have been left unburied upon a field of battle.

2. Salted beef and pork.

3. Locusts.

4. Raw hides confined in stores, and in the holds of ships.

5. A whale thrown upon the sea shore in Holland.

6. A large bed of oysters. The malignant fevers which prevailed in

Alexandria, in Virginia, in 1803, and in Southwark, adjoining

Philadelphia, in the year 1805, were derived from this cause[11].

[11] It has been a common practice with many families, in New-York and

Philadelphia, for several years past, to lay in a winter store of

oysters in their cellars in the fall of the year. May not a part

of these oysters, left in these cellars from forgetfulness, or

from being unfit for use, become, by putrifying there, the cause

of malignant fevers in the succeeding summer and autumn?

7. The entrails of fish. And,

8. Privies. The diarrh[oe]a and dysentery are produced, oftener than any

other form of summer and autumnal disease, by the f[oe]tor of privies.

During the revolutionary war, an American regiment, consisting of 600

men, were affected with a dysentery, from being encamped near a large

mass of human fæces. The disease was suddenly checked by removing their

encampment to a distance from it. Five persons in one family were

affected with the yellow fever in Philadelphia, in 1805, who lived in a

house in which a privy in the cellar emitted a most offensive smell. No

one of them had been exposed to the foul air of Southwark, in which the

fever chiefly prevailed in the autumn of that year. Three of them

sickened at the same time, which obviated the suspicion of the disease

being produced by contagion.

There are several other sources of malignant fevers besides those which

have been mentioned. They are, exhalations from volcanoes, wells, and

springs of water; also flesh[12], fish, and vegetables, eaten in a

putrid state; but these seldom act in any country, and two of them only,

and that rarely, in the United States.

[12] The following fact, communicated to me by Mr. Samuel Lyman, a

member of congress from the state of Massachusetts, shows the

importance of attending to the condition of butchers' meat in our

attempts to prevent malignant fevers.

A farmer in New-Hampshire, who had overheated a fat ox by

excessive labour in the time of harvest, perceiving him to be

indisposed, instantly killed him, and sent his flesh to a

neighbouring market. Of twenty four persons who ate of this flesh,

fifteen died in a few days. The fatal disease produced by this

aliment fell, with its chief force, upon the stomach and bowels.

The usual forms of the disease produced by miasmata from the sources of

them which have been enumerated are,

1. Malignant or bilious yellow fever.

2. Inflammatory bilious fever.

3. Mild remittent.

4. Mild intermittent.

5. Chronic, or what is called nervous fever.

6. Febricula.

7. Dysentery.

8. Colic.

9. Cholera morbus.

10. Diarrh[oe]a.

In deriving all the above forms of disease from miasmata, I do not mean

to insinuate, that sporadic cases of each of them are not produced by

other causes.

In designating them by a single name, I commit no breach upon the ancient

nomenclature of medicine. The gout affects not only the blood-vessels and

bowels, but every other part of the body, and yet no writer has, upon

that account, distinguished it by a plural epithet.

The four last of the forms of disease, that have been mentioned, have

been very properly called intestinal states of fever. They nearly accord,

in their greater or less degrees of violence and danger, with the first

four states of fever which occupy the blood-vessels, and in the order in

which both of them have been named. I shall illustrate this remark by

barely mentioning the resemblance of the yellow fever to the dysentery,

in being attended with costiveness in its first stage, from a suspended

or defective secretion or excretion of bile, and in terminating very

generally in death, when not met by the early use of depleting remedies.

The variety in the forms and grades of the summer and autumnal disease,

in different seasons, and their occasional changes into each other in the

same seasons, are to be sought for in the variety of the sensible and

insensible qualities of the atmosphere, of the course of the winds, and

of the aliments of different years.

II. The means of preventing the different forms of disease that have been

mentioned, come next under our consideration.

Happily for mankind, Heaven has kindly sent certain premonitory signs of

the most fatal of them. These signs appear,

I. Externally, in certain changes in previous diseases, in the

atmosphere, and in the animal and vegetable creation.

II. In the human body.

1. The first external premonitory sign that I shall mention is, an

unusual degree of violence in the diseases of the previous year or

season. Many proofs of the truth of this remark are to be met with in the

works of Dr. Sydenham. It has been confirmed in Philadelphia, in nearly

all her malignant fevers since the year 1793. It would seem as if great

and mortal epidemics, like the planets, had satellites revolving round

them, for they are not only preceded, but accompanied and followed, by

diseases which appear to reflect back upon them some of their malignity.

But there is an exception to this remark, for we now and then observe

uncommon and general healthiness, before the appearance of a malignant

epidemic. This was the case in Philadelphia, previously to the fevers of

1798 and 1799. I have ascribed this to the stimulus of the pestilential

miasmata barely overcoming the action of weak diseases, without being

powerful enough to excite a malignant fever.

2. Substances, painted with white lead, and exposed to the air, suddenly

assuming a dark colour; and winds from unusual quarters, and unusual and

long protracted calms, indicate the approach of a pestilential disease.

The south winds have blown upon the city of Philadelphia, ever since

1793, more constantly than in former years. A smokiness or mist in the

air, the late Dr. Matthew Wilson has remarked, generally precedes a

sickly autumn in the state of Delaware.

3. Malignant and mortal epidemics are often preceded by uncommon sickness

and mortality among certain birds and beasts. They have both appeared,

chiefly among wild pigeons and cats in the United States. The mortality

among cats, previous to the appearance of epidemics, has been taken

notice of in other countries. Dr. Willan says it occurred in the city of

London, between the 20th of March and the 20th of April, in the year

1797, before a sickly season, and Dr. Buneiva says it preceded a mortal

epidemic in Paris. The cats, the doctor remarks, lose, on the second day

of their disease, the power of emitting electrical sparks from their

backs, and, when thrown from a height, do not, as in health, fall upon

their feet[13].

[13] Medical Journal, vol. iv.

4. The common house fly has nearly disappeared from our cities,

moschetoes have been multiplied, and several new insects have appeared,

just before the prevalence of our late malignant epidemics.

5. Certain trees have emitted an unusual smell; the leaves of others have

fallen prematurely; summer fruits have been less in size, and of an

inferior quality; and apples and pears have been knotty, in the summers

previous to several of our malignant autumnal fevers. Dr. Ambrose Parey

says, an unusually rapid growth of mushrooms once preceded the plague in

Paris.

II. The premonitory signs of an approaching malignant epidemic in the

human body are,

1. A sudden drying up, or breaking out of an old sore; fresh eruptions in

different parts of the body; a cessation of a chronic disease, or a

conversion of a periodical into a continual disease. Of this there were

many instances in Philadelphia, in the year 1793.

2. A peculiar sallowness of the complexion. This was observed to be

general in Philadelphia, previous to the yellow fever of 1793. Dr. Dick

informed me, that he had observed the same appearance in the faces of the

people of Alexandria, accompanied in some cases with a yellowness of the

eyes, during the summer of 1793, and previous to the appearance of a

violent bilious fever on the banks of the Potomac.

3. I have observed one or more of the following symptoms, namely,

head-ach; a decay, or increase of appetite; costiveness; a diminished or

increased secretion of urine; a hot and offensive breath[14]; constant

sweats, and sometimes of a f[oe]tid nature, or a dry skin; wakefulness,

or a disposition to early or protracted sleep; a preternaturally frequent

pulse; unusual vivacity, or depression of spirits; fatigue and sweats

from light exertions; hands, when rubbed, emitting a smell like hepar

sulphuris; and, lastly, a sense of burning in the mouth; to be present in

different persons, during the prevalence of our malignant epidemics.

[14] I have once known this breath, in a gentleman who had carried the

seeds of the yellow fever in his body from Philadelphia into its

neighbourhood, create sickness at the stomach in his wife; and I

have heard of an instance in which a person, who left Philadelphia

when highly impregnated with the miasmata of the same fever,

creating sickness at the stomach in four or five persons who sat

at the same table with him in the country. None of the above

persons were afterwards affected by the fever. In an anonymous

history of the plague in London, in the year 1664, in the

possession of the author, it is said, the breath was a well-known

signal of infection to persons who were not infected, and that

whenever it was perceived, individuals and companies fled from it.

The sickness in the above-mentioned persons was similar to that

which is sometimes excited by the smell of a sore leg, or a

gun-shot wound, upon the removal of its first dressing. It does

not produce fever, because there is no predisposition to it.

The means of preventing the different forms of our summer and autumnal

disease come next under our consideration. I shall first mention such as

have been most effectual in guarding against its malignant form, and

afterwards take notice of such as are proper in its milder grades. These

means naturally divide themselves again,

I. Into such as are proper to protect individuals.

II. Such as are proper to defend whole communities from the disease. And,

III. Such as are proper to exterminate it, by removing its causes.

I. Of the means of protecting individuals.

Where flight is practicable, it should be resorted to in every case, to

avoid an attack of a malignant fever. The heights of Germantown and Darby

have, for many years, afforded a secure retreat to a large number of the

citizens of Philadelphia, from their late annual epidemics. It were to be

wished our governments possessed a power of compelling our citizens to

desert the whole, or parts, of infected cities and villages. In this way

the yellow fever was suddenly annihilated in Providence, on

Rhode-Island, and in New-Haven, in Connecticut, in the year 1805. But the

same power should rigorously prevent the removal of the sick, except it

be that class of them which have neither homes nor friends. The less the

distance they are carried beyond the infected atmosphere, the better. The

injury sustained by conveying them in a jolting carriage, for two or

three miles, has often been proclaimed in the reports of our city

hospitals, of patients being admitted without a pulse, and dying a few

hours afterwards.

In leaving a place infected by miasmata, care should be taken not to

expose the body to great cold, heat, or fatigue, for eighteen or twenty

days, lest they should excite the dormant seeds of the disease into

action.

But where flight is not enforced by law, or where it is not practicable,

or preferred, safety should be sought for in such means as reduce the

preternatural tone and fulness induced in the blood-vessels by the

stimulus of the miasmata, and the suppression of customary secretions.

These are,

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