FRUCTUS PRUNI.

_Prunes_; F. _Pruneaux à médecine_.

=Botanical Origin=—_Prunus domestica_ L., var. ζ. _Juliana_ DC.—It is

from this tree, which is known as _Prunier de St. Julien_,[962] that

the true _Medicinal Prunes_ of English pharmacy are derived. The tree

is largely cultivated in the valley of the Loire in France, especially

about Bourgueil, a small town lying between Tours and Angers.

=History=—The plum-tree (_P. domestica_ L.) from which it is supposed

the numerous cultivated varieties have descended, is believed to occur

in a truly wild state in Greece, the south-eastern shores of the Black

Sea (Lazistan), the Caucasus, and the Elburz range in Northern Persia,

from some of which countries it was introduced into Europe long before

the Christian era. In the days of Pliny, numerous species of plum were

already in cultivation, one of which afforded a fruit having laxative

properties.

Dried prunes, especially those taking their name from Damascus (_Pruna

Damascena_), are frequently mentioned in the writings of the Greek

physicians, by whom as well as at a later period by the practitioners

of the Schola Salernitana, they were much employed.

[961] Gmelin, _Chemistry_, vii. 389; xv. 422.

[962] Loiseleur-Deslongchamps et Michel, _Nouveau Duhamel, ou Traité

des arbres et arbustes que l’on cultive en France_, v. (1812) 189, pl.

54. fig. 2, pl. 56. fig. 9.

In the older London pharmacopœias, many sorts of plum are enumerated,

but in the reformed editions of 1746, 1788, and 1809, the French Prune

(_Prunum Gallicum_) is specially ordered, its chief use being as an

ingredient of the well-known _Lenitive Electuary_; and this fruit

is still held by the grocers to be the legitimate _prune_. The same

variety is regarded in France as the prune of medicine.

=Description=—The prune in its fresh state is an ovoid drupe of a deep

purple hue, not depressed at the insertion of the stalk, and with

a scarcely visible suture, and no furrow. The pulp is greenish and

rather austere, unless the fruit is very ripe; it does not adhere to

the stone. The stone is short (⁷/₁₀ to ⁸/₁₀ of an inch long, ⁵/₁₀ to

⁶/₁₀ broad), broadly rounded at the upper end and slightly mucronulate,

narrowed somewhat stalk-like at the lower, and truncate; the ventral

suture is broader and thicker than the dorsal.

The fruit is dried partly by solar and partly by fire-heat, that is to

say, it is exposed alternately to the heat of an oven and to the open

air. Thus prepared, it is about 1¼ inches long, black and shrivelled,

but recovers its original size and form by digestion in warm water.

The dried pulp or sarcocarp is brown and tough, with an acidulous,

saccharine, fruity taste.

=Microscopic Structure=—The skin of the prune is formed of small,

densely packed cells, loaded with a dark solid substance; the pulp

consists of larger shrunken cells, containing a brownish amorphous mass

which is probably rich in sugar. This latter tissue is traversed by a

few thin fibro-vascular bundles, and exhibits here and there crystals

of oxalate of calcium. By perchloride of iron, the cell-walls, as well

as the contents of the cells, acquire a dingy greenish hue.

=Chemical Composition=—We are not aware of any analysis having been

made of the particular sort of plum under notice, nor that any attempt

has been made to discover the source of the medicinal property it is

reputed to possess. Some nearly allied varieties have been submitted

to analysis in the laboratory of Fresenius, and shown to contain

saccharine matters to the extent of 17 to 35 per cent., besides malic

acid, and albuminoid and pectic substances.[963]

=Uses=—The only pharmaceutical preparation of which the pulp of prunes

is an ingredient, is _Confectio Sennæ_, the _Electuarium lenitivum_ of

the old pharmacopœias. The fruit stewed and sweetened is often used as

a domestic laxative.

=Substitute=—When French prunes are scarce, a very similar fruit,

known in Germany as _Zwetschen_ or _Quetschen_, is imported as a

substitute.[964] It is the produce of a tree which most botanists

regard as a form of _Prunus domestica_ L., termed by De Candolle var.

_Pruneauliana_. K. Koch,[965] however, is decidedly of opinion that it

is a distinct species, and as such he has revived for it Borkhausen’s

name of _Prunus œconomica_. The tree is widely cultivated in Germany

for the sake of its fruit, which is used in the dried state as an

article of food, but is not grown in England.

[963] Liebig’s _Ann. der Chemie_, ci. (1857) 228.

[964] This was especially the case in the winter of 1873-74.

[965] _Dendrologie_, part i. (1869) 94.

The dried fruit differs slightly from the ordinary prune in being

rather larger and more elongated, and having a thicker skin; also

in the stone being flatter, narrower, pointed at either end, with

the ventral suture much more strongly curved than the dorsal. The

fruits seem rather more prone to become covered with a saccharine

efflorescence.

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