In order to forestall the putting into action of their impulse it is

important that those who are close to the patient should have some

realisation of the possibility of its occurrence. There are usually

some signs beforehand of the possibility of the crime. Many of these

early suicides have distinct tendencies to and stigmata of hebephrenic

melancholia. The best known symptoms of this condition are those

described by Dr. Peterson, the present president of State Commission

of Lunacy of New York in his book on mental diseases. The symptoms

noted are extraordinarily rapid and paradoxical changes of

disposition. Depressed ideas intrude themselves in the midst of

boisterous gaiety, and untimely jocularity in the deepest depression,

or at solemn moments. Then there is the paradoxical facial expression,

the so-called paramimia, that is, a look of joy and pleasure when

really mental depression is present, or a look of depression when

joyful sentiments {310} are being expressed. The existence of such

rather noticeable peculiarities may lead to the suspicion of mental

disequilibration in young people.

The most important warning may well be the occurrence of suicide in

any other member of the family for several generations before. The

tendency of suicide to repeat itself in families is now well known and

recognised. During the year 1901 in New York City, in one case other

members of the immediate family had committed suicide in six

instances. The subject has taken on additional interest because of the

suicide of a well-known gambler who was the fourth of his family in

two generations to take his own life. In another case, reported within

the last five years, the suicide was the last of a family of nine

children, every one of whom had committed suicide. There is the record

in the German army of four generations of a noble family, the eldest

son of which committed suicide during the 5 years from 50 to 55.

In these cases the tendency to suicide is not directly inherited, but

there is a mental weakness that makes the individual incapable of

withstanding the sufferings life may entail. In the later members of

the family there is also a suggestibility that the frequent

contemplation of the idea of suicide finally leads to the putting off

of the natural abhorrence at the thought of its commission. In such

families, therefore, it is particularly important to warn medical

attendants and members of the family of the possibilities of

unfortunate acts so as to prevent if possible the execution of any

impulse to self-murder.

JAMES J. WALSH.

{311}

XXVIII

VENEREAL DISEASES AND MARRIAGE

Syphilis is a disease that is contagious, inoculable, and

transmissible by heredity. It may be acquired innocently, and it is so

acquired in about 4 per centum of cases according to good authority,

but the other 96 per centum is venereal. The disease attacks any part

of the body within and without from the soles of the feet to the hair

and finger-nails. The first evidence, where the case is not

hereditary, is a hardened sore called a chancre; next the lymphatic

glands swell, and many forms of skin-eruption occur; then follows a

chronic inflammation of the cellulo-vascular tissues and the bones,

and small tumours, called gummata, may develop in almost any part of

the body. The disease may vary from a light attack to malignancy.

There are periods in the course of the disease.

1. The period of primary incubation, or the time from infection to the

appearance of the chancre. This is commonly three weeks.

2. The primary stage: the chancre forms and the neighbouring glands

are affected. This stage lasts from three to ten days.

3. The secondary incubation, or the time between the appearance of the

chancre and the development of what are called the secondary

symptoms,--usually about six months.

4. The secondary stage. Here occur fever, anaemia, neuralgic pains,

and the eruptions on the skin and the mucous membranes. This period

lasts from twelve to eighteen months in the majority of cases.

5. The intermediate period. During this time there may be no symptom,

or slighter recurrence of the secondary {312} symptoms. This period

lasts from two to four years. It may end in recovery of health or be

followed by tertiary symptoms.

6. The tertiary stage. In this period gummata form, or there may be

diffuse infiltration of various parts of the body, chronic

inflammation and ulceration of the bones, skin and other tissues,

nervous diseases, and so on. The tertiary stage commonly begins from

three to four years after the primary infection.

The three chief divisions, which are apt to blend one into the other,

are the primary, secondary, and tertiary periods.

The affections of the secondary stage are often severe. There may be

fever associated with weakness, headache, general malaise and pain,

and this may be marked or rather light. In this stage iritis is liable

to occur, and if it is not properly diagnosed and treated it will

result in blindness.

The lesions of the tertiary stage may cause great destruction of

tissues and very grave consequences. Cerebral syphilis, if unchecked,

will inevitably cause paralysis or paresis. There may be loss of

speech, epilepsy, coma, paralyses, apoplectic hemiplegia, and so on.

The pain is harassing and often it amounts to great anguish. Whatever

part of the brain substance is destroyed will not be restored.

In syphilitic affections of the spinal cord, if the inflammation is

acute death ensues in a few days or weeks. _Tabes dorsalis_, or

locomotor ataxia, is caused in about 93 per centum of cases of this

disease by syphilis, and it is an incurable and dreadful malady.

If there is neuritis from the virus it becomes intense and causes

muscular contractions, paresis, and paralysis. The optic, auditory,

and olfactory nerves may be attacked and destroyed. The nose also may

be destroyed and it commonly caves in. The bones of the face are

frequently attacked in the tertiary stage and they rot away. The tibia

is diseased more frequently than the other long bones.

The heart is rarely injured, but when it is, the prognosis usually is

bad. In a large number of cases death is sudden and unexpected. If the

arteries are involved the prognosis again is bad, because the symptoms

here do not show until {313} too late for effective treatment When the

liver is the seat of gummata these may be cured in the early stage,

but in the later stage the prognosis is unfavourable. Some forms of

renal syphilis are remediable, but others are not, especially the

interstitial kind.

Syphilis is transmitted to a child congenitally, not as a tendency or

predisposition, but as an active contagion. It may come from the

father, the mother, from both parents, or by direct infection.

The transmission from the father is the most frequent. The spermatozoa

carry the infection to the maternal ovum. Down to the end of the

secondary stage, and half through the intermediate period between the

secondary and tertiary stages of syphilis, a father or mother may

beget a child that will be infected with hereditary syphilis, a

shivering, blasted, rotten little wretch for whom a quick death is the

greatest imaginable blessing, and it usually gets this blessing. In

the acute stage of a virulent syphilis the disease is most likely to

be transmitted; but sometimes, though rarely, a father that has been

free from all symptoms of syphilis for many years may beget a child

that is born with a virulent hereditary form of the disease.

Infection by the mother is more certain and more harmful than that

from the father, because the intrauterine life of the child is

poisoned throughout its course. Two-thirds of the cases of hereditary

syphilis die either by abortion, or if they live to term they die

shortly after delivery. If the mother is infected during the first

eight months of pregnancy the child will nearly always be syphilitic,

but if she is infected after the eighth month the child may escape.

If at the moment of conception both parents have the disease the child

will almost certainly take it, and this infection will cause its

death. In a series observed by Fournier, 28 per centum of the cases

caused by paternal infections died and 37 per centum showed the luetic

taint; in the cases caused by maternal infection 60 per centum died,

and 84 per centum had syphilitic lesions; in the mixed heredity, that

is when both the father and mother were luetic, 68.5 per centum died

and 92 per centum were born syphilitic. When a child {314} is first

infected at delivery the case is not technically classed as hereditary

syphilis.

During the first year after the father or mother has taken syphilis

the probability of infecting the child is the greatest. In the third

year the liability of infecting the child is lessened, but present. In

a series of 562 cases of hereditary syphilis observed by Fournier, 60

children, over 10 per centum, were infected more than six years after

the primary parental infection. Carefully observed cases have been

exceptionally found where infection of the child has occurred in the

fifteenth and even the twentieth year after the original parental

lesion. Fournier reports the case of one woman that had nineteen

consecutive stillbirths from syphilis.

Mild parental syphilis may transmit hereditarily the most malignant

type of the disease, and very virulent parental infection may result

in a comparatively mild infection of the child, if any infection by

syphilis may be called mild. That the parent shows no symptoms from an

old infection is no proof that he or she is cured, or that the child

may not be infected.

With proper treatment of the mother the infantile mortality in

hereditary syphilis is reduced from 59 per centum to 3 per centum, and

the children that are born living are not unfrequently free from

syphilis. When a woman is infected at the conception of her child

miscarriage takes place before the child is viable, from the first to

the sixth month; later other miscarriages occur; later still, living

but syphilitic children are born, of whom one-fourth die within the

first six months; finally she may have children that are not infected.

If a syphilitic man has been properly treated he may, after four

years, beget healthy children, and he commonly does, but he may be the

father of syphilitic children. Syphilitic women properly treated may,

after about six years from infection, bring forth healthy children,

and they commonly do, but not always.

There is a wide diversity of opinion among the best authorities

concerning the curability of syphilis. Gowers (_Syphilis and the

Nervous System_. 1892) says: "There is no evidence that the disease

ever is or ever has been cured, the {315} word 'disease' being here

used to designate that which causes the various manifestations of the

malady." He means there is no absolute proof that a person who has

once been infected is ever so fully cured that he may marry without

danger of transmitting the disease.

Fournier requires, as the minimum time, four years of methodical

treatment before he deems the patient safe, but even this arbitrary

fixing of the number of years is not warranted by experience. Many

physicians hold that in the tertiary stage the disease is not

transmissible, but that statement is not true. Commonly it is,

sometimes it is not. After all symptoms have disappeared the disease

has been transmitted.

In short, a person that wittingly marries any one who has had syphilis

at any time is a fool; and if one of the contracting parties has had

syphilis within the four years preceding the marriage the marriage is

criminal, even if the syphilis has been carefully and skilfully

treated by a physician.

Gonorrhoea is always a dangerous disease. In the male, beside the

acute lesions, it can cause chronic or fatal inflammations along the

various parts of the genito-urinary tract or in different organs of

the body. When the disease becomes chronic it lasts indefinitely. It

may then cause cystitis, or so affect the kidneys as to bring about

very grave results; it may get into the circulation and induce

gonorrhoeal rheumatism of the joints, especially of the knee joint,

and result in a partly or completely stiffened joint. The heart may be

affected and endocarditis ensue; there may be meningitis or

inflammation of the cerebral membranes; the eye may be infected, and

unless it is skilfully treated blindness will follow. Strictures of

the male urethra from chronic gonorrhoeal inflammation often require

major surgical operations for relief.

The disease in women has most of these complications, and other grave

peculiar phases. All prostitutes have acute or chronic gonorrhoea, and

12 per centum, probably more, of reputable women are infected; and the

suffering caused is very great. The gonococcus remains virulent for

two or three years at the least in a man's chronic gleet, and if he

marries he infects his wife. Should her womb be infected {316} she is

seldom completely cured. If the Fallopian tubes are involved, and this

happens frequently, they suppurate, and often they must be removed by

coeliotomy. The woman suffers for a long time when the tubes are

attacked by the disease, and she becomes sterile ordinarily.

When a child is born to a woman that has gonorrhoea its eyes are

infected at delivery, and if it is not very skilfully treated it will

surely lose its sight. Because of this danger, in maternity hospitals

the eyes of all babies are treated at delivery as a precaution, and

many physicians observe the same precaution in private practice.

When, therefore, a man has chronic gonorrhoea he should not marry

until about four years after the last infection, and he should be

carefully treated in the meantime. There is a popular opinion that

gonorrhoea is a trifling disease, but the contrary is the truth: it is

a grave disease, especially in women; and the person that carelessly

infects another is certainly guilty of crime for which a long term in

jail would be a light punishment.

AUSTIN OMALLEY.

{317}

XXIX

SOCIAL DISEASES

There are certain affections not at all uncommon and as a rule

producing rather serious effects upon the social body, of which,

though their existence is well known to all, very little is said. It

is certain that what is considered the more severe of these venereal

diseases may be acquired quite innocently. Indeed, many thousands of

cases of this affection, acquired innocently, have now been reported

by medical men in this country alone. If the statistics of all the

world were gathered together, there would probably be a hundred

thousand cases of this dreadful affection, which have been acquired

without any blame on the part of the sufferer. It has become the

custom, especially in English speaking countries, to ignore the

presence of these diseases, and this has led to a multiplication of

opportunities for their spread to such a degree that now the condition

of affairs, for those who know it best, is rather alarming. It is with

the intention that a few definite ideas, given absolutely without

exaggeration and without any striving after effect, may enlist

clergymen, as well as physicians, in a crusade against these diseases,

that the present chapter is written.

It has been said over and over again at medical society meetings that

it is a very unfortunate thing that universities in these modern times

are situated in large cities. The young man just freed from the

restraints of home life, or of the seclusion of a college, is at once

without any preliminary training, exposed to all the dangers, moral

and physical, of large city life. Not only is this true, but he is

even not properly warned of the dangers that lie so close to his path.

Our prudery has gone so far that the very names of these {318}

affections are tabooed and above all must not be mentioned before the

young. As to the awful evils that such diseases may cause, as to the

lifelong suffering, even to mental degeneration and early death, that

they may involve, not even a hint is considered to be proper. The

consequence is that young men expose themselves not infrequently to

danger, absolutely unknowing the significance that such diseases have

in recent years acquired in the minds of modern physicians, and it is

usually not until a serious mistake has been made that the young man

is brought in contact with the physician who may be frank in pointing

out evils utterly unknown before.

This state of affairs has come to be considered as so irrational in

many foreign universities that now a special course of lectures is

given every year on the significance of what may be called the social

diseases. The students are told very frankly what the possibilities of

danger for them in certain excesses may be, so that at least the young

man can not say "I knew nothing about it," when the risk becomes an

actual reality of danger. At the University of Berlin the first course

of such lectures was established, and the interest aroused and the

results obtained were such as to make other universities consider the

advisability of such lectures for their students. Even here in prim

and prude America, one or two of the great universities have come to

the realisation that the physical well being of their students is

committed to their care, as well as their intellectual development,

and at least a beginning of that precious wisdom that comes from the

fear of the physical evils of sin has been acquired because of

opportunities provided by the faculty.

It is well admitted now by all that ignorance is not innocence and

that knowledge of the consequences of social diseases is likely to be

a very important factor in preventing young men from taking risks that

would otherwise be considered very slight, perhaps. As a matter of

fact, nothing can be more helpful from the ethical standpoint than

this knowledge of how closely may follow the wages of sin, which is

death. It is for this reason that clergymen would seem to owe it, as a

duty to themselves and their position in social {319} life, to acquire

a certain knowledge of these affections. A very great change has come

over the attitude of the medical profession towards the so-called

venereal diseases in recent years. A quarter of a century ago they

were considered to be not very serious after all, and indeed in some

cases to be no more serious than a cold, a mere passing incident in

life. Now it is well recognised that almost never do they leave their

victim in the state of health in which he was before, and that

unfortunately the deterioration of tissues which has taken place is

likely to be enduring. Even many years afterwards there may be serious

complications involving health or even life.

For instance, it is now very generally conceded that paresis, or what

is sometimes called general paralysis of the insane,--a progressive

mental and nervous disease, which invariably ends fatally in from

three to seven years,--is always due to one of the so-called social or

venereal diseases. How important this affection has become in modern

life can be best appreciated from the fact that in Europe nearly one

in four of those who die in the insane asylums are sufferers from

paresis. In this country the disease is not so frequent, the

proportion being less than one in five or even one in six. The disease

is becoming more and more common, however, as large city life becomes

more prominent, and as the possibility of infection with social

diseases is more widespread.

Paresis is what is sometimes called softening of the brain, and it

attacks by preference men under thirty-five. The first symptoms of it

as a rule are not alarming. A young man's disposition changes, so that

an individual heretofore rather stingy becomes extravagant, while

occasionally a prodigal becomes very saving and considers that he has

already a large sum of money to his credit. The most prominent feature

of the early stage of the disease is the occurrence of delusions of

grandeur, that is to say, the patients get the idea that they are

important personages, or that they have fallen heirs to a large sum of

money, or that they have been appointed to high salaried positions. As

a consequence of these delusions, they may make expensive presents to

their friends. Occasionally there are other changes in disposition. A

young {320} man, for instance, who has been of genial character

becomes morose and hard to live with. The opposite change to greater

liveliness of disposition is not unknown, but is more infrequent.

Sometimes there are marked excesses, high living, luxurious habits,

and the like, before the existence of disease is recognised.

The mental stigmata of the disease at the beginning are not alarming

at all. There are slight lapses of memory. A man who has hitherto been

known as an accurate mathematician, makes frequent mistakes in adding

or multiplying. The physical signs are even slighter. In using long

words, syllables are omitted from them. A favourite method of testing

the speech of a person suspected of beginning paresis is to ask for

the pronunciation of a word like Constantinople. Usually a syllable

will be elided, and the reply will be "Constanople," or something

similar. There is a slight tremulousness of the hands and usually a

rather easily marked tremor of the lips, especially when the tongue is

protruded. Often in the very earliest stage of the disease, there are

changes in the pupils. They may be unequal, or may fail entirely to

react to light.

When these signs are positive, that is, when there is a change in

disposition and then the physical stigmata that we have gone over

appear, the diagnosis of the disease is almost certain. The physician

is able to say, with considerable assurance, that the young, strong,

healthy-looking patient, who has often had to be tempted to come to

see the doctor by some specious reason, because he does not consider

himself that he has anything wrong with him, will have to be confined

in an asylum within a year, or at most, two, and will die in a state

of dementia within five years. This, of course, is an awful picture.

This is the course of the disease in nearly 20 per centum of the

inmates of our asylums. Almost without exception there is a history of

syphilis in these cases, and the medical world is now persuaded that

this is the most important factor in the production of paresis.

Another nervous disease, corresponding in some of its features to

paresis and indeed sometimes spoken of as a spinal form of paresis, is

locomotor ataxia. This affection {321} begins usually with loss of

sensation in the soles of the feet so that the patient thinks that he

is walking on carpet all the time. Before this there may have been

some disturbance of vision. The pupils may fail to react to light.

Occasionally the first symptoms are motor, that is, the man notices

that he is not able to walk as readily as before. He staggers easily.

If he tries to turn round while walking he is apt to lose his balance.

If he tries to walk in the dark, he is almost sure to have so great a

sense of insecurity that he dare not go far from the wall.

Occasionally the first sign is a sinking of the limbs on the way down

stairs. In certain very sad cases, the first and only symptom is a

failure of sight which goes on progressively, until the optic nerve is

completely destroyed and sight forever rendered impossible.

All these symptoms are traceable directly to certain changes which

have been noted in the spinal cord. These changes are due to

disturbance of the blood and lymph supply of the nervous tissue. Once

the changes have taken place, there is no hope of the patient ever

recovering the normal use of his limbs. Not infrequently he becomes

bedridden and can not walk at all because he is not able to steady

himself. He may not suffer in his general health, however, to any

serious extent, and may live on for twenty years, though usually his

resistive vitality is lowered and he is carried off by some

intercurrent disease.

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