In the course of time this lodge was visited by the clever I

AN ESSAY ON

HASHEESH

INCLUDING

OBSERVATIONS AND EXPERIMENTS

BY

VICTOR ROBINSON

_Contributing Editor, Medical Review of Reviews_,

_Pharmaceutical Chemist, Columbia University_,

_Member of the American Chemical Society_,

_Author of_ “_Pathfinders in Medicine_.”

[Illustration]

MEDICAL REVIEW OF REVIEWS

TWO HUNDRED AND SIX BROADWAY

NEW YORK

1912

COPYRIGHT, 1912

BY MEDICAL REVIEW OF REVIEWS

“What is left for us modern men? We cannot be Greek now.

The cypress of knowledge springs, and withers when it comes

in sight of Troy; the cypress of pleasure likewise, if it

has not died already at the root of cankering Calvinism;

the cypress of religion is tottering. What is left?

Science, for those who are scientific. Art for artists; and

all literary men are artists in a way. But science falls

not to the lot of all. Art is hardly worth pursuing now.

What is left? Hasheesh, I think: Hasheesh of one form or

another. We can dull the pangs of the present by living the

past again in reveries or learned studies, by illusions

of the fancy and a life of self-indulgent dreaming. Take

down the perfumed scrolls; open, unroll, peruse, digest,

intoxicate your spirit with the flavor. Behold, here is

the Athens of Plato in your narcotic visions; Buddha

and his anchorites appear; the raptures of St. Francis

and the fire-oblations of St. Dominic; the phantasms of

mythologies; the birth-throes of religion, the neurotism of

chivalry, the passion of past poems; all pass before you

in your Maya world of hasheesh, which is criticism.”--JOHN

ADDINGTON SYMONDS.

An Essay on Hasheesh

INCLUDING OBSERVATIONS AND

EXPERIMENTS.

By VICTOR ROBINSON.

“And now, borne far thru the steaming air floats an odor,

balsamic, startling; the odor of those plumes and stalks

and blossoms from which is exuding freely the narcotic

resin of the great nettle. The nostril expands quickly, the

lungs swell out deeply to draw it in: fragrance once known

in childhood, ever in the memory afterward, and able to

bring back to the wanderer homesick thoughts of midsummer

days in the shadowy, many-toned woods, over into which is

blown the smell of the hemp-fields.”

ALLEN: _The Reign of Law_.

“At the mere vestibule of the temple I could have sat and

drunk in ecstasy forever, but lo! I am yet more blessed. On

silent hinges the doors swing open, and I pass in.”

LUDLOW: _The Hasheesh Eater_.

Ailing man has ransacked the world to find balms to ease him of his

pains. And this is only natural, for what doth it profit a man if he

gain the whole world and lose his digestion? Let the tiniest nerve

be but inflamed, and it will bend the proudest spirit: humble is a

hero with a toothache! It is doubtful if Buddha himself could have

maintained his equanimity with a bit of dust on his conjunctiva.

Cæsar had a fever--and the eye that awed the world did lose its

lustre, and the tongue that bade the Romans write his speeches in

their books cried like a sick girl. Our flesh is heir to many ills,

and alas when the heritage falls due. Even pride and prejudice are

then forgotten, and Irishmen in need of purgatives are willing to use

rhubarb grown on English soil, while the Foreign Colombo gathered by

the feral natives in the untamed forests of Quilimani is consumed by

ladies who never saw anything wilder than a Fabian Socialist.

The modern descendant of Hippocrates draws his Materia Medica from

the uttermost ends of the earth: linseed from busy Holland and

floretted marigold from the exotic Levant; cuckoo’s cap from little

Helvetia, and pepper-elder from ample Brazil; biting cubebs from

spicy Borneo and fringed lichens from raw-winded Iceland; sweet flag

from the ponds of Burmah, coto bark from the thickets of Bolivia,

sleeping nightshade from the woods of Algeria, brownish rhatany

from the sands of Peru, purple crocus from the pastures of Greece,

aromatic vanilla from the groves of Mexico, golden seal from the

retreats of Canada, knotty aleppo from the plains of Kirghiz,

fever-tree from the hills of Tasmania, white saunders from the

mountains of Macassar. Idols are broken boldly nowadays, but the

daughter of Æsculapius does not fear, for Hygeia knows she will

always have a frenzied world of worshippers to kneel at her every

shrine in every land.

All the reservoirs of nature have been tapped to yield medicines for

man. From the mineral kingdom we take the alkali metals, the nitrogen

group, the compounds of oxygen, the healing waters, the halogens, the

nitrate of silver, the sulphate of copper, the carbonate of sodium,

the chloride of mercury, the hydroxide of potassium, the acetate of

lead, the citrate of lithium, the oxide of calcium, and the similar

salts of half a hundred elements from Aluminium to Zincum.

From the vegetable kingdom we extract the potent alkaloid; all things

that blossom and bloom, we knead them as we list: the broad rhizome

of iris, the wrinkled root of lappa, the inspissated juice of aloes,

the flower-heads of anthemis, the outer rind of orange, the inner

bark of cinnamon, the thin arillode of macis, the dense sclerotium of

ergot, the ovoid kernel of nutmeg, the pitted seed of rapa, the pale

spores of club-moss, the spongy pith of sassafras, the bitter wood of

quassia, the smoothish bark of juglans, the unripe fruit of hemlock,

the fleshy bulb of scilla, the brittle leaves of senna, the velvet

thallus of agaric, the balsamic resin of benzoin, the scaly strobiles

of hops, the styles and stigmas of zea.

The animal kingdom has likewise been forced to bring tribute to its

highest brother: we use in medicine the blood-sucking leech, the

natural emulsion from the mammary glands of the cow, the internal

fat from the abdomen of the hog, the coppery-green Spanish fly,

the globular excrements of the leaping antelope, the fixed oil

from the livers of the cod, the fresh bile of the stolid ox, the

vitellus of the hen’s egg, the fatty substance from the huge head

of the sperm-whale, the odorous secretion of the musk-deer, the

swimming-bladder of regal fish, the inner layer of the oyster-shell,

the branched skeleton of the red polyp, the dried follicles of the

boring beaver, the bony horns of the crimson deer, the thyreoid

glands of the simple sheep, the coagulated serum from the blood of

the horse, the wax and the honey from the hive of the busy bee, and

even the disgusting cockroaches that infest the kitchen-shelves and

climb all over the washtubs are used as a diuretic and for dropsy.

Little it matters by whom the healing agent was ushered in, for

mankind in its frantic search for health asks not the creed or color

of its medical savior: Pipsissewa was introduced into medicine by the

redskins, buchu by the hottentots, quassia by a negro slave, zinc

valerianate by a French prince, krameria by a Spanish refugee, ipecac

by the Brazilian aborigines, guaiac by a syphilitic warrior, aspidium

by a Swiss widow.

“Medicine,” wrote the greatest of literary physicians, “appropriates

everything from every source that can be of the slightest use to

anybody who is ailing in any way, or like to be ailing from any

cause. It learned from a monk how to use antimony, from a Jesuit how

to cure agues, from a friar how to cut for stone, from a soldier

how to treat gout, from a sailor how to keep off scurvy, from a

postmaster how to sound the Eustachian tube, from a dairy-maid how

to prevent small-pox, and from an old market-woman how to catch the

itch-insect. It borrowed acupuncture and the moxa from the Japanese

heathen, and was taught the use of lobelia by the American savage.”

And all these substances are daily being powdered, sifted,

granulated, desiccated, percolated, macerated, distilled, sublimed,

comminuted, dissolved, precipitated, filtered, strained, expressed,

clarified, crystallized, ignited, fused, calcined, torrified and

deflagrated into powders, pills, wafers, capsules, ampoules,

extracts, tinctures, infusions, decoctions, syrups, cordials,

essences, magmas, suppositories, tablets, troches, ointments,

plasters, abstracts, liniments, collodions, cataplasms and so on and

so on.

And all these finished preparations have a most laudable object in

view--the eradication of disease and the alleviation of pain. Ah,

this is indeed a quest worth the striving for! To accomplish the

quadrature of the circle, or ferret out the secret of perpetual

motion, may be highly interesting, tho of problematical value

only; but when a clammy sweat bathes the brow, and the delicate

nerves twitch till the tortured human frame shakes in anguish, how

important is it to be able to lift the veil from a condition like

this! He who conquers disease is greater than the builder of cities

or the creator of empires. His value is above the poets, statesmen

cannot be compared unto him, educators equal him not in worth. A

careful economist like John Stuart Mill tells us it is doubtful if

all the labor-saving machinery ever invented has lessened for a

single day the work of a single human being,--but when a discovery

is made in medicine it becomes a sun which sheds its beneficence

on all who suffer. The sick pauper of to-day lying in a charity

hospital receives better medical treatment than the sick potentate of

yesterday lying in his costly palace.

But so far medical science has only unhorsed, not overthrown, its

ancient antagonist. In spite of all the remedies, in spite of all

the research, mankind as yet possesses no satisfactory antidote for

suffering; it knows no drug which can give pain its _congé_ for more

than a transient period.

But altho the time of relief be limited, the simple fact that there

are substances which do have some power over pain is sufficient

to make the study of narcotism highly important. And of all the

narcotics--a narcotic being roughly defined as a substance which

relieves pain and produces excitability followed by sleep--none is

more alluring to the imagination than the intoxicating hemp-plant,

scientifically known as _Cannabis sativa_ and popularly famed as

Hasheesh--those strange flowering-tops that appeal to a pot-bellied

bushman of Australia who smokes it in a pipe of animal tusks, and

to so hyper-esoteric a _littérateur_ as Charles Baudelaire of the

Celestial City of Art.

The habitat of the hemp-plant is extensive: not by the hand of man

were the seeds sown that gave it birth near the Caspian Sea, where it

wildly flourishes on the banks of the immense Volga--that mighty mass

of liquid ever stupendously rolling thru a limitless continent; it

climbs the Altai range and thrives where the Himalaya rears its stony

head ten thousand feet on high; it extends to Persia, and China knows

it; the Congo river and the hot Zambesi bathe it in Africa, it is not

a stranger in sunny France, and how well it thrives in Kentucky the

numerous readers of the _Reign of Law_ will ever remember.

In the seventeenth century Rumphius noticed that there were

differences between the hemp grown in India and the hemp grown

in Europe. In the nineteenth century Lamarck accepted these

distinctions, and believing the Indian hemp to be a separate species,

agreed in calling it _Cannabis indica_ as a distinction from the

_Cannabis sativa_ of Linnæus and Willdenow. But it is now conceded

that from a botanical standpoint the variations are by no means

certain or important enough to warrant the maintenance of Indian hemp

as a species distinct from common hemp. And as the greater includes

the lesser, in botany as well as in geometry, its botanical name is

_Cannabis sativa_, with _Cannabis indica_ as one variety, just as

_Cannabis americana_ is another variety.

The hemp grown in Russia is of a fibrous quality, and is largely used

for the gallows--to hang the opponents of despotism. In England many

a bold highwayman has been embraced by it the last moment of his

roving life, and has thus philanthropically given his mother-tongue

a chance to enrich herself. For instance, a hempie means a rascal

for whom the hemp grows; a hempen collar means the hangman’s noose;

a hempen widow means one whose husband has been hanged; to sow hemp

means to live in a manner likely to lead to the gallows. Rope,

however, is not the only use to which the fibers can be put; they

are extensively employed in clothing, and in the manufacture of paper.

The plant is also cultivated for its seeds, which contain a large

quantity of oil, and is therefore used in pharmacy for emulsions,

and in the domestic arts because of its drying properties. But the

seeds are chiefly used as a favorite food for birds. In fact, some

birds consume them to excess, which should lead us to suspect that

these seeds, tho they cannot intoxicate us, have a narcotic effect

on the feathered creatures, making them dream of a happy birdland

where there are no gilded cages, and where the men are gunless and

the women hatless. The seeds also contain sugar and considerable

albumin,--making them very nutritious; rabbits eat them readily. They

are consumed also by some human beings, but are not as good as the

sunflower seeds which Marianka ceaselessly and carelessly crunched,

while Olenine looked upon her moving lips with a lover’s despair.

The medicinal hemp--the hemp with the potent narcotic principles--is

_Cannabis indica_. In this case we have an example of Compensation

that would have made Emerson’s eyes glisten, for altho the fibrous

texture of hemp disappears under a southern sun, to make up for the

loss there is secreted a resin--_Churrus_. This resin is collected

in a most singular manner. During the hot season, according to

Dr. O’Shaughnessy, men clothed in leather run violently thru the

hemp-fields and brush forcibly against the plants. The soft, sticky

resin adheres to the garments, and is later scraped off and kneaded

into balls. Dr. M’Kinnon informed Dr. O’Shaughnessy that in the

province of Nipal the leather attire is dispensed with, and that the

natives run naked thru the hemp fields, gathering the resin on their

bare bodies.

When the larger leaves turn brown and fall to the ground, it is

an indication of the approach of maturity. The flowering tops are

then cut off, and subjected to a process of rolling and treading by

trained human feet. The hemp is placed on a hard floor surrounded

by a rail; the natives take hold of a revolving post, march around

and around, singing the while, and press the plants in a technical

manner. Whether the perspiration which drips from their unshod

organs of locomotion works any chemical change in the composition of

Cannabis has not yet been determined by E. M. Holmes or E. W. Dixon.

It is not surprising to learn that the dealing in Hasheesh is a

Government monopoly, and that heavy punishment is meted out to those

offenders who buy or sell it without permission. “The importation of

it into Egypt is so strongly interdicted,” explains the _Dispensatory

of the United States_, “that the mere possession of it is a penal

offense; we found it, however, readily procurable. It is said to be

brought into the country in pigs’ bladders, in the Indo-European

steamers, and thrown out at night during the passage into the

Suez canal, to be picked up by the boats of confederates.” This

deplorable state of affairs is apt to remind us of our own temperance

towns--where there are always some individuals who possess the

faculty of obtaining whisky _ad libitum_.

_Cannabis sativa_ is a member of the _Moraceæ_ or Mulberry Family,

which family was formerly an order of apetalous dicotyledenous trees

or shrubs, but is now reduced to a tribe of the _Urticaceæ_ or Nettle

Family which embraces 110 genera and 1500 species.

Cannabis is an annual herb, and thus endures but one year, because

instead of storing away nutritious matter in underground bulbs and

tubers like the industrious biennials or perennials, it exultingly

expends its new-born energy in the production of beautiful blossoms

and the maturation of fruit and seed. “This completed,” says Asa

Gray, “the exhausted and not at all replenished individual perishes.”

Sexually, hemp is diœcious, which means that its staminate and

pistillate organs are not on the same plant. When cultivated for its

narcotic properties, only the flowering tops of the unfertilized

female plants are used, and the male plants are eradicated with

great care, as it is claimed that a single one can spoil an entire

field--something like a Boccaccion gentleman in a nunnery. The

process of weeding out the males is performed by an expert called a

poddar, who brings to his work a conscious technical skill, and an

unconscious but interesting argument in illustration of what Lester

F. Ward has described as the Androcentric World View, for the poddar

deliberately reverses the names of the sexes, and designates the

useful females as males, and calls the rejected males the females.

If we had such impudent poddars in the animal world, no doubt the

valuable Miss Jane Addams would be metamorphosed into James, while

the unnecessary Mr. Anthony Comstock would be adorned with a feminine

appellation.

Cannabis is from 4 to 12 feet in height; its stem is angular,

branching, and covered with matted hairs; its leaves are palmate

and therefore roughly resemble an open hand; its leaflets are

lance-shaped, possessing margins dentated with saw-like teeth; its

flowers are yellow and axillary, the male cluster being a raceme and

therefore pedicelled, and the female a spike and consequently sessile

or stemless; the five male organs or stamens contain pendulous

double-celled sacs or anthers; the two female organs or pistils have

glandular stigmas, the stigma being the spot where fertilization

occurs; the fruit is a gray nut or achene, each containing a single

oily seed; the whole plant is covered with a scarcely visible down;

the roughness of the leaves and stem is due to the silica, which is a

characteristic of the plants of the _Moraceæ_.

Not much need be said of the microscopical characteristics of hemp,

for altho the powder contains several histological elements, as

pollen grains, glands, crystals, resin, fibres, vessels, stone cells,

epidermis, parenchyma,--indicating presence of stem, leaf, flower,

seed,--its characteristic hairs or trichomes with their cystolith

deposits are of sufficient diagnostic value to make it readily

recognizable.

Unfortunately, when we come to the chemical constituents of

Cannabis, certainty is at an end. As Dorvault’s _L’Officine_ says,

“La composition chimique du cannabis indica est mal connue.” The

conquests of man are peculiar: he lays a cable under the roaring

ocean, and he flashes his messages thru limitless miles of space;

beneath the surface of the earth he rides on an iron horse, and

bird-like he sails thru the trackless air. But put this common drug

before him and he cannot determine its chemical composition. The

careful experimenters and the expert assayers are balked.

“I have extracted an alkaloid from hasheesh,” says Preobraschensky,

“and it is potent.” “No, we have found the active constituent,” say

T. and H. Smith; “it is the resin cannabin.” “No,” says Personne,

“I have isolated the important ingredient; it is the amber-colored

volatile oil, cannabene.” “Oh, no,” says Frankel, “I have discovered

the active principle--it is a phenol aldehyde.” “No, indeed,” say

Wood, Spivey and Easterfield, “it is we who have separated the only

active ingredient--it is a red oil, cannabinol.” “Oh, not at all,”

says Hamilton, “not one of these is the active constituent; in fact,

the active constituent has not yet been isolated.” In such an arena,

where the masters dispute, it behooves the amateur to speak with a

stammering tongue.

That doubt should prevail on this subject is all the more remarkable

when we consider that hemp has been known from a time whereof the

mind of man runneth not to the contrary--to use a phrase which seems

to delight the lawyers. In the _Odyssey_, a thousand years before

the advent of the Christian era, Homer sang of the assuager of

grief or Nepenthes, which is believed to have been the hemp-plant.

Hemp thus comes ushered into history, held in the beautiful hand

of Helen. Hesychius narrates that the Thracian women made sheets

of hemp. Pliny says hemp was known to the Romans, who manufactured

cordage from it. The Father of History relates that the Scythians

threw the seeds of hemp on red-hot stones, and bathed themselves in

the vapor, crying with exultation. Moschion records that the ship

_Syracusia_, built for Hiero--kinsman of Archimedes--was rigged

with hempen ropes. In the most ancient of all Hindu medical works,

_Susruta_, hemp is recommended for catarrh. The Pandit Moodoosudun

Gooptu found in the _Rajniguntu_ a clear account of hemp. A Sanskrit

work on Materia Medica, _Rajbulubha_, alludes to the use of hemp

in gonorrhea. According to Kamalakantha Vidyalanka, hemp was early

forbidden to pious Brahmins. The old Arabic and Persian writers

made numerous references to cannabis, and declared its narcotic

properties were discovered by Haider. Haider was a rigid monk who

built a monastery on the mountains between Nishabor and Ramah. For

ten years he never left his hermitage, never indulged in even a

fleeting moment’s pleasure. One burning summer’s day when the fiery

sun glared angrily upon Mother Earth as if he wished to wither up

her breasts, Haider stepped out from his cloister and walked alone

to the fields. All around him lay the vegetation weary and without

life, but one plant danced in the heat with joy. Haider plucked

it, partook of it, and returned to the convent a happier man. The

monks who saw him immediately noticed the change in their chief. He

encouraged conversation, and acted boisterously. He then led his

companions to the fields, and the holy men partook of the hasheesh,

and were transformed from austere ascetics into jolly good fellows.

At the death of Haider, in conformity with his desire, his disciples

planted the hemp in an arbor around his tomb.---- In that portion

of the Chinese herbal, _Rh-ya_, which was written 500 B.C., the

seed and flower-bearing kinds of hemp are noticed. In the first

century, Dioscorides--the most renowned of the ancient writers on

Materia Medica--recommended the seeds in the form of a cataplasm to

soothe inflammation. In the second century, Galen wrote that it was

customary to give hemp to guests at banquets to promote hilarity

and happiness. At the beginning of the third century, the physician

Hoa-Thoa used hemp as an anesthetic in surgical operations. In the

thirteenth century, garments of hemp became common thruout Southern

Europe, and it may well be that Beatrice herself wore it when Dante

first saw the maiden in her father’s house.

There is a remarkable episode in the history of Hasheesh, indicating

how the character of a people may be affected by the surrounding

vegetation. Mohammedanism, like all other theologies, has been rent

by schisms, and the question as to who was the legitimate successor

of the Prophet split this Oriental faith into two great sects--the

Sunnis and the Shiahs. The latter were the heretics, as they

considered Mohammed’s son-in-law the true imam. The Shiahs themselves

were further subdivided into several parties, the Ismaelites being

the most important. The Ismaelites were especially powerful in

Persia, and later--thru the instrumentality of an escaped prisoner

who seized the throne--gained a firm foothold in Egypt. A grand lodge

was formed in the city of Cairo--on the banks of the river whose

ancient waters heard the hammering at the quarries for the rearing

of the Great Pyramid. Many rules were now made by the Ismaelites,

and the petty race of perishable men was much flustered, while the

immortal Nile flowed indifferently from its equatorial cradle,

refreshing the crimson water-lilies, bathing the reeds that lined

its shore, and wetting the sands where the thoughtful Sphinx opens

not its lips.

In the course of time this lodge was visited by the clever Ismaelite,

Hassan Ben Sabbah--a boyhood friend of Omar Khayyám--who was received

with acclamation. Hassan soon received enough honors to excite

jealousy, and while plotting for more power was defeated and forced

to disappear from Egypt, but, after traveling awhile, he settled near

Kuhistan. He gathered around him a considerable number of followers,

and by strategy, in 1090, captured the powerful Persian fortress of

Alamut. Hassan now introduced a new feature into his society--the

employment of secret murder against all enemies. It was the Sheikh of

this organization who loomed large in medieval folk-lore as the Old

Man of the Mountains. Many young men became disciples, and willingly

performed the bloody work. These youths were known as the _Fedais_

or Devoted Ones. When a Devoted One was selected to commit murder,

he was first stupefied with hasheesh, and while in this state was

brought into the magnificent gardens of the sheikh. All the sensual

and stimulating pleasures of the erotic orient surrounded the

excited youth, and exalted by the delicious hypnotic he had taken,

the hot-blooded fanatic felt that the gates of heaven were already

ajar, and heard them swing open on their golden hinges. When the

effect of the drug disappeared and the Devoted One was reduced to his

normal condition, he was informed that thru the generosity of his

superior he had been permitted to foretaste the delights of Paradise.

The Devoted One believed this readily enough--disciples are always

credulous--and therefore was eager to die or to kill at a word from

his master. From these hasheesh-eaters, the Arabian name of which

is _hashshashin_, was derived the term “assassin.” It is not known

at what date the epithet was first applied to other secret slayers.

The Assassins soon became a terrible scourge, and the very sands of

the desert almost learnt to tremble before them. Many an unprepared

breast felt their daggers, and many a surprised stomach tried in

vain to vomit up their poisons. Prince and calif they struck down,

and more than one haughty chief paid tribute to the Old Man of the

Mountains. During the invasion of Palestine by the Crusaders, the

Syrian branch of the Assassins reached its bloody zenith, and who

shall say how many high-born damsels wept for knightly shields that

lay low in the dust of Lebanon? The power of the Assassins was

destroyed in Persia about the middle of the thirteenth century, and

some years later the Mameluke sultan of Egypt exterminated them in

Syria. But just as there are still some Innsbruck Jesuits who pray

for the revival of the Spanish Inquisition, so some remnants of

the Assassins yet linger between the Tigris river and the mount of

Taurus--but what of that? The Old Man of the Mountains now sleeps in

Death’s Valley, and not all the hasheesh from Bengal could exalt him.

Towards the end of the eighteenth century, when Napoleon invaded

Egypt--and grew philosophic as he met the gaze of the prehistoric

pyramids--hasheesh was brought prominently to the notice of

Europeans by the accounts of DeSacy and Rouger. By this time its

narcotic properties must have been known to the Occidentals, for as

far back as 1690 Berlu in his _Treasury of Drugs_ described it as

“of an infatuating quality and pernicious use.” Nevertheless, its

introduction into the Pharmacopeias of Europe and the United States

is due mainly to the elaborate experimentation carried on during

1839 and several succeeding years by the talented Dr. William B.

O’Shaughnessy, Professor of Chemistry in the Medical College of

Calcutta.

This brings us to the physiological action of Cannabis. It primarily

stimulates the brain, has a mydriatic effect upon the pupil, slightly

accelerates the pulse, sometimes quickens and sometimes retards

breathing, produces a ravenous appetite, increases the amount of

urine, and augments the contractions of the uterus. In other words,

it has an effect on the nervous, respiratory, circulatory, digestive,

excretory and genito-urinary systems.

As a therapeutic agent hasheesh has its eulogizers, tho like many

other drugs it has been replaced by later remedies in various

disorders for which it was formerly used. Old drugs, like old folks,

must give way to the new, and even the therapeutic master-builders

must beware when the young generation of healing-agents knocks on the

door of health.

In medicinal doses Cannabis is used as an aphrodisiac, for neuralgia,

to quiet maniacs, for the cure of chronic alcoholism and morphine and

chloral habits, for mental depression, hysteria, softening of the

brain, nervous vomiting, for distressing cough, for St. Vitus’ dance,

and for the falling sickness so successfully simulated by Kipling’s

Sleary--epileptic fits of a most appalling kind. It is used in spasm

of the bladder, in migraine, and when the dreaded _Bacillus tetanus_

makes the muscles rigid. It is a uterine tonic, and a remedy in the

headaches and hemorrhages occurring at the final cessation of the

menses. It has been pressed into the service of the diseases that

mankind has named in honor of Venus. According to Osler, cannabis

is sometimes useful in locomotor ataxia. Christison reports a case

in which Cannabis entirely cured the intense itching of eczema,

while the patient was enjoying the delightful slumber which the

hemp induced. It is much employed as an hypnotic in those cases

where opium because of long-continued use has lost its efficiency.

As a specific in hydrophobia it is sometimes marvelous, for Dr. J.

W. Palmer writes that he himself has seen a sepoy, an hour before

furiously hydrophobic, under the influence of cannabis drinking water

freely and pleasantly washing his face and hands! Its function in

this unspeakable affliction should be investigated carefully, for it

will be a gala day for mankind when it can cease to fear Montaigne’s

terrible line: “The saliva of a wretched dog touching the hand of

Socrates, might disturb and destroy his intellect.”

The official definition of _Cannabis indica_ as given by the Eighth

Decennial Revision of our _Pharmacopeia_ is as follows: “The dried

flowering tops of the pistillate plants of _Cannabis sativa_ Linné

(Fam. _Moraceæ_), grown in the East Indies and gathered while the

fruits are yet undeveloped, and carrying the whole of their natural

resin.” Three preparations of the drug are official: an Extract, a

Fluid-extract, and a Tincture.

In the last (third) edition of the _National Formulary_, hemp enters

into four galenicals: in chloral and bromine compound which is used

as a sedative and hypnotic, in chloroform Anodyne which is used in

diarrhoea and cholera, in Brown Sequard’s anti-neuralgic pills, and

in corn collodion. Hemp is a constituent in the majority of corn

remedies. Not many drugs are used for both the brain and the feet,

but with cannabis we have this anomaly: a man may see visions by

swallowing his corn-cure.

Out of the enormous number of prescriptions in which hasheesh

enters as an ingredient, only half a dozen can be here represented.

In Hager’s _Pharmaceutische Praxis_ occurs this prescription for

gonorrhea:

=℞=

Kali nitrici

Natri nitrici ana 5,0

Extracti Hyoscyami 0,5

Aquæ Amygdalarum amararum 10,0

Emulsionis Cannabis fructus 200,0

For dysmenorrhea the _Journal de Médecine de Paris_ recommends the

following suppositories, with the directions that one be introduced

every evening, commencing with the fifth day before the menses:

=℞=

Ex. cannab. indicæ gr. ¼

Ex. belladonnæ gr. ¼

Ol. theobrom. q. s.--M.

For phthisis, when accompanied by insomnia and nervous dyspepsia, Dr.

S. G. Bonney prescribes:

=℞=

Strychnin, sulph. gr. ⅔

Extracti opii gr. j

Extracti cannabis indicæ gr. j ss

Salolis gr. c.

Aloini gr. ss.--M.

Pone in capsulas No. xx

Dr. Rankin fights dyspepsia with the following formula, one capsule

being given after meals:

=℞=

Zinci valeratis ʒj

Acidi carbolici gr. xl

Acidi arsenosi gr. ss

Extracti cannabis indicæ. gr. v.--M.

Pone in capsulas No. xx.

When a patient of Van Harlingen is attacked with _ichthyosis

hystrix_, the disagreeable skin-disease finds itself daily painted

with this preparation:

=℞=

Acid. salicylici ʒss

Ex. cannabis ind gr. x

Collodii f℥j--M.

Dr. Da Costa endeavors to relieve impotence by giving his patients,

morning and evening, this pill:

=℞=

Ex. cannabis indicæ

Ex. nucis vomicæ aa gr. xv

Ex. ergotae aquosi ʒj.--M.

Et. ft. pil. No. xxx

The results of the prolonged use of large doses of Cannabis are thus

epitomized by Alfred Stillé: “The habitual use of this drug entails

consequences no less mischievous than are produced by alcohol

and opium; the face becomes bloated, the eyes injected, the limbs

weak and tremulous, the mind sinks into a state of imbecility, and

death by marasmus is the ultimate penalty paid for the overstrained

pleasure it imparts.”

Poisoning by hasheesh is treated by the administration of emetics

(what poison isn’t), lemon-juice, tannin, coffee, ammonia,

strychnine, atropine, spirit of nitrous ether. Electricity and

artificial respiration are often useful.

A strange thing about hasheesh is that an overdose has never produced

death in man or the lower animals. Not one authentic case is on

record in which Cannabis or any of its preparations destroyed life.

We thus have a poison which lacks a maximum and a fatal dose. Indeed,

if we desire to be finical, we can claim that according to what

is now considered the best definition of a poison, Cannabis is no

poison at all, for the aforesaid best definition defines a poison

as “any substance which is capable of causing death, otherwise than

mechanically, when introduced into the body or applied to it”--and

Cannabis does not seem capable of causing death by chemical or

physiological action.

“Hemp,” says Professor Horatio C. Wood, “is not a dangerous drug;

even the largest doses of its active preparations, altho causing most

alarming symptoms, do not compromise life.”

“We have never been able,” testify Drs. Houghton and Hamilton, “to

give an animal a sufficient quantity of the drug to produce death.

When study of the drug was first commenced, careful search on the

literature of the subject was made to determine its toxicity. Not a

single case of fatal poisoning have we been able to find reported,

altho often alarming symptoms may occur. A dog weighing about 25

pounds received an injection of 2 ounces of the U. S. P. fluidextract

in the jugular vein, with the expectation that it would certainly

be sufficient to kill the animal. To our surprise the animal after

being unconscious for about a day and a half, recovered completely.

Another dog received about 7 grams of the solid extract with the

same result.”

That herbivorous animals are even less affected by it I know from

my own simple experiments. I gave a rabbit a drachm and a half of

the fluidextract of cannabis. No sooner did I release the animal

than it began to nibble a commonplace vegetable, indifferent to

the circumstance that it had been baptised with the most precious

opiate of the orient. For four hours I watched this member of the

genus _Lepus_, but no physical effects could be observed, while the

mild expression of its gentle eyes induced me to conclude that all

mental manifestations were lacking to such a degree that the bunny

still worshiped the rather material trinity of crackers, carrots and

cabbages. This rabbit was sold to an experienced dealer, and sometime

later while passing the store, I learnt it had become the sire of a

goodly progeny, but what I really would like to learn is this: will

those little innocent rabbits--with their asinine ears and angelic

eyes--ever know of their father’s enforced hasheesh debauch?

Few creatures have so slight a hold on life as the pretty

guinea-pig--which does not come from Guinea and is not a pig. A

blow of the hand, a bit of moisture, a breath of cold, and their

squealing is done. But they do not mind cannabis. I chose a fine

fellow, anesthetized his glossy back with ethyl chloride, and then

by means of a hypodermic syringe injected 100 minims of the powerful

fluidextract into his circulation. There were no results. After the

elapse of some hours the generous cavy so far forgot the incident as

to pull some sweet-pea pods from my hand.

Dr. O’Shaughnessy says that all his experiments “tended to

demonstrate that, while carnivorous animals and fish, dogs, cats,

swine, vultures, crows, and adjutants invariably and speedily

exhibited the intoxicating influence of the drug, the graminivorous,

such as the horse, deer, monkey, goat, sheep, and cow, experienced

but trivial effects from any dose we administered.” Lieutaud and

Mabillat say the same.

Up to this period we have considered hasheesh from the historic,

botanic, microscopic, chemic, physiologic, therapeutic and

pharmacologic viewpoints: what then remains? Why, friends, the best

is yet to be, the last for which the first was made--as Browning

would say.

Why has everyone heard of opium? Because of its somnifacient and

myotic properties? No, but because sixty million pounds are consumed

by people for the purpose of pleasure. It is the same with hasheesh.

All heathens use it to increase their joys: Moors, Mohammedans,

Malays, Burmese, Siamese, Hindoos, Hottentots, Australian Bushmen

and Brazilian Indians--three hundred millions of them. The grateful

Orientals have endowed their hasheesh with such epithets as exciter

of desire, increaser of pleasure, cementer of friendship, leaf of

delusion, the laughter-mover, causer of the reeling gait. “It is real

happiness,” says Monsieur Moreau, and Herbert Spencer quotes the

sentence in his _Principles of Psychology_,--“It is real happiness

which hasheesh causes.”

It is unreasonable to suppose that a powerful narcotic like cannabis

will produce uniform results in all instances, when it is notorious

that even coffee affects different people in different ways; one

lady drinks tea to keep her awake at night, and her neighbor

drinks it to put her asleep; an Havana cigar irritates Brown and

tranquillizes Jones; a glass of grog causes one man to beat his

children, and induces another to give away his coat to strangers.

The constitutional peculiarity of the subject must always be taken

into consideration: some folks are so absurd as to become afflicted

with nettle-rash after partaking of delicious strawberries; others

are poisoned by an egg; some become ill in the presence of the

violet, and others faint when they smell the lily; Tissot mentions a

person who vomited if he took a grain of sugar; Louis XIV had grand

manners, but he preferred the odor of cat’s urine to that of the red

rose. “Jack Sprat could eat no fat, his wife could eat no lean.”

Idiosyncrasy may not be the star performer, but it certainly plays an

important rôle in the therapeutic drama.

No drug in the entire Materia Medica is capable of producing

such a diversity of effects as cannabis indica. “Of the action of

hasheesh,” writes Professor Stillé, “many and various descriptions

have been given which differ so widely among themselves that they

would scarcely be supposed to apply to the same agent, had we not

every day a no less remarkable instance of the same kind before us

in the case of alcohol. As the latter enlivens or saddens, excites

or depresses, fills with tenderness, or urges to brutality, imparts

vigor and activity, or nauseates and weakens, so does the former give

rise to even a still greater variety of phenomena, according to the

natural disposition of the person, and his existing state of mind,

the quantity of the drug, and the combinations in which it is taken.”

And not only is there a contrariety and dissimilarity of action,

but sometimes there is no action at all. Cannabis is certainly

the coquette of drugdom. Take agaric, and it will stop your

perspiration--take jaborandi, and it will sweat you half to death;

take creosote, and it will prevent emesis--take ipecac, and it

will vomit you till your very guts cry out for mercy; take eserine,

and your pupils will contract--take atropine, and they will dilate;

veratrine will make you sneeze, the dust of sanguinaria will give you

a bloody nose, aloes will act on your lower bowel, podophyllum will

work on the upper, squill will make you pass water by the quart, an

injection of strychnine will stimulate you, a dose of morphine will

put you in the arms of Morpheus,--but take cannabis, and who can

predict the result? It may do wondrous things to you, and it may let

you strictly alone.

To a worker on the Associated Press named I. M. Norr, I gave 30

minims of the fluidextract. There were no results. To a law student

named Aaron Wolman, I gave 40 minims. There was no more effect than

if he had taken 40 drops of water. It must be added, however, that

these experimenters, instead of putting themselves in a receptive

state, had determined beforehand to fight the influence of the drug.

On the evening of May 18th, 1910, I gave 25 minims to Dr. Anna

Mercy, and altho she threw herself at the shrine of science in a way

that must have astonished the sober old altar of experiment, there

were no results worth mentioning, except that while in the evening

she looked respectable, in the morning she looked disreputable.

Had all my experiments turned out thus, this essay would never have

been written. But I have had results fully as interesting as those

achieved by O’Shaughnessy, Moreau, Mabillat, Reidel, Schroff, Wood,

Bell, Christison, Aubert, and many others, including our gifted

traveler-poet Bayard Taylor.

My brother Frederic Robinson took 25 minims in the presence of

some ladies whom he had invited to witness the fun. An hour passed

without results. A second hour followed, but--to use the slang of

the street--there was nothing doing. The third hour promised to

be equally fruitless, and as it was already late in the evening,

the ladies said good-by. No sooner did they leave the room, than I

heard the hasheesh-laugh. The hemp was doing its work. In a shrill

voice my brother was exclaiming, “What foo-oolish people, what

foo-oo-ool-ish people to leave just when the show is beginning.”

The ladies came back. And it was a show. Frederic made Socialistic

speeches, and argued warmly for the cause of Woman Suffrage. He grew

most affectionate and insisted on holding a lady’s hand. His face was

flushed, his eyes were half closed, his abdomen seemed uneasy, but

his spirit was happy. He sang, he rhymed, he declaimed, he whistled,

he mimicked, he acted. He pleaded so passionately for the rights of

Humanity that it seemed he was using up the resources of his system.

But he was tireless. With both hands he gesticulated, and would brook

no interruption.

Peculiar ideas suggested themselves. For instance, he said something

was “sheer nonsense,” and then reasoned as follows: “Since shears are

the same as scissors, instead of sheer nonsense I can say scissors

nonsense.” He also said, “I will give you a kick in the tickle”--and

was much amused by the expression.

At all times he recognized those about him, and remained conscious

of his surroundings. When the approach of dawn forced the ladies

to depart, Frederic made a somewhat unsavory joke, and immediately

exclaimed triumphantly, “I wouldn’t have said that if the ladies

were here for a million dollars.” Someone yawned deeply, and being

displeased by the unexpected appearance of a gaping orifice, Frederic

melodramatically gave utterance to this Gorky-like phrase: “From

the depths of dirtiness and despair there rose a sickly odorous

yawn”--and instantly he remarked that the first portion of this

sentence was alliterative! Is it not strange that such consciousness

and such intoxication can exist in the same brain simultaneously?

The next day he remembered all that occurred, was in excellent

spirits, laughed much and easily, and felt himself above the petty

things of this world.

On May 19th, 1910, this world was excited over the visit of Halley’s

comet. It is pleasant to remember that the celestial guest attracted

as much attention as a political campaign or a game of baseball.

On the evening of this day, at 10 o’clock, I gave 45 minims to a

court stenographer named Henry D. Demuth. At 11.30 the effects of

the drug became apparent, and Mr. Demuth lost consciousness of his

surroundings to such an extent that he imagined himself an inhabitant

of Sir Edmund Halley’s nebulous planet. He despised the earth and

the dwellers thereon; he called it a miserable little flea-bite,

and claimed its place in the cosmos was no more important than a

flea-jump. With a scornful finger he pointed below, and said in a

voice of contempt, “That little joke down there, called the earth.”

“Victor,” he said, “you’re a fine fellow, you’re the smartest man in

Harlem, you’ve got the god in you, but the best thoughts you write

are low compared to the things we think up here.” A little later he

condescended to take me up with him, and said, “Victor, we’re up in

the realm now, and we’ll make money when we get down on that damned

measly earth again; they respect Demuth on earth.”

He imitated how Magistrate Butts calls a prisoner to

the bar. “Butts,” he explained, “is the best of them.

Butts--Buts--cigarette-butts.” If this irrelevant line should ever

fall beneath the dignified eyes of His Honor, instead of fining

his devoted stenographer for contempt of court, may he bear in his

learned mind the fact that under the influence of narcotics men are

mentally irresponsible.

By this time Mr. Demuth’s vanity was enormous. “God, Mark Twain and I

are chums,” he remarked casually. “God is wise, and I am wise. And to

think that people _dictate_ to me!”

He imagined he had material for a great book. “I’m giving you the

thoughts; slap them down, we’ll make a fortune and go whacks.

We’ll make a million. I’ll get half and Vic will get half. With

half a million we’ll take it easy for a while on this damned

measly earth. We’ll live till a hundred and two, and then we’ll

skedaddle didoo. At one hundred and two it will be said of Henry

Disque Demuth that he shuffled off this mortal coil. We’ll skip

into the great idea--hooray! hooray! Take down everything that is

signifi_cant_--with an accent on the _cant_--Immanuel Kant was a wise

man, and I’m a wise man; I am wise, because I’m wise.”

It is to be regretted that in spite of all the gabble concerning

the volume that was to make both of us rich, not even one line was

dictated by the inspired author. In fact he got no further than the

title, and it must be admitted that of all titles in the world, this

is the least catchy. It is as follows: “Wise is God; God is Wise.”

Later came a variation in the form of a hissing sound which was

meant to be an imitation of the whizzing of Halley’s comet; there

was a wild swinging of the sheets as a welcome to the President;

a definition of religion as the greatest joke ever perpetrated;

some hasheesh-laughter; and the utterance of this original epigram:

Shakespeare, seltzer-beer, be cheerful.

A little later all variations ceased, for the subject became a

monomaniac, or at any rate, a fanatic. He became thoroly imbued with

the great idea that the right attitude to preserve towards life is

to take all things on earth as a joke. Hundreds and hundreds and

hundreds of times he repeated: “The idea of the great idea, the idea

of the great idea, the idea of the great idea.” No question could

steer him out of this track. “Who’s up on the comet? Any pretty girls

there?” asked Frederic. “The great idea is up there,” was the answer.

“Where would you fall if you fell off the comet?”

“I’d fall into the great idea.”

“What do you do when you want to eat and have no money?”

“You have to get the idea.”

“When will you get married?”

“When I get the idea.”

Midnight came, and he was still talking about his great idea. At one

o’clock I felt bored. “If you don’t talk about anything else except

the idea, we’ll have to quit,” I said.

“Yes,” he replied, “we’ll all quit, we’ll all be wrapped up in

the great idea.” He took out his handkerchief to blow his nose,

remarking, “The idea of my nose.” I approached him. “Don’t

interfere,” he cried, “I’m off with the great idea.”

An essay on hasheesh · 第 1 / 3 段