Prognosis in particular diseases involves the consideration not only

of those signs of the general vital condition to which we have just

been giving attention, but also of such as are more or less peculiar

to each disorder. To a certain extent these signs may be grouped. We

may refer to good and bad signs in pulmonary, cardiac, intestinal,

renal, cerebral, and febrile affections respectively. Still, there

will be for each malady, if it really has a distinctive character,

some tokens which experience shows to be specially indicative of

favorable or unfavorable progress and results.

Let us notice some of these as examples.

In pneumonia the best signs are the lowering of a high temperature,

reduction of the number of respirations to 20 or 25 in the minute,

expectoration of sputa less and less tinged with red or brown, and

gradual reduction of the region of dulness on percussion. Worst, in

the same disease, are an axillary temperature over 106°, respirations

40 or more per minute, with delirium, and expectoration becoming more

abundant, grayish, and purulent; also with continued dulness on

percussion and abundant mucous râles on auscultation.

In croup the best sign is, after a hoarse, dry, barking cough and

dyspnoea, a soft, liquid râle, heard in the larynx and trachea during

respiration or coughing. Worst, in croup, is a steadily or

paroxysmally increasing difficulty of breathing, with a dry hissing or

whistling sound of respiration and cough succeeding the barking sounds

of the earlier stage.

In phthisis pulmonalis among the best signs are the patient's

increasing in weight, coughing and expectorating less, ceasing to have

hectic and night sweats. These may give renewed hope, even before much

change is discernible in the physical signs. Of bad omen are intense

hectic fever, incessant cough with abundant nummular sputa, copious

perspirations, diarrhoea, breathing growing shorter and shorter, and

extreme emaciation and debility.

In all organic affections of the heart an extremely rapid and

irregular pulse, with orthopnoea and increasing anasarca, and

especially the Cheyne-Stokes respiration (described under DIAGNOSIS),

must cause unfavorable expectations.

In obstruction of the bowels the best of all symptoms is, usually, of

course, a copious fecal evacuation. Yet a few cases have occurred in

which a very large evacuation, delayed by obstruction for a week or

two, has been almost immediately followed by collapse and death. The

worst signs in cases of obstruction are (besides long-unyielding

constipation) {171} stercoraceous vomiting, a small, rapid pulse, and

increasing coldness and clamminess of the surface of the body.

In cholera infantum the best signs are cessation of vomiting and

purging, the discharges growing more nearly natural, the face becoming

less shrunken in aspect, sleep taking the place of coma vigil or

waking apathy, and water or milk, when taken, remaining on the

stomach. Worst, in the same disease, are incessant rejection of

everything swallowed, watery passages from the bowels every half hour

or hour, shrinking of the face and body to skin and bone, with an

apathetic expression of the open or half-open eyes, the latter rolling

often from side to side.

In epidemic cholera good signs are the arrest of vomiting and of

rice-water discharges from the bowels, rapid movement of the blood in

the veins after removal of momentary pressure, return of natural color

and warmth to the skin, with filling up of the pulse at the wrist. Bad

signs in cholera are shrinking of the cheeks and of the flesh upon the

hands, deepening ashiness or blueness of the skin, coldness and

clamminess to the touch, dyspnoea, loss of pulse, incessant vomiting

and purging of rice-water stools, constant cramps of the limbs, and

suppression of urine.

In acute cerebral meningitis good signs are lessened temperature of

the head, quiet sleep without stertor, disappearance of delirium, more

natural pulse, and attention to surrounding objects, without

disquietude. Bad signs in the same disease are deep stupor,

strabismus, convulsions, paralysis, involuntary defecation and

urination.

In typhus fever good signs are the pulse becoming slower and fuller,

the skin less hot, more soft and moist, the tongue moist and clean,

the face losing its dusky flush, and consciousness returning instead

of muttering delirium.[40] Bad, in the same fever, are deepening of

the flush of the countenance, profound stupor, rapid and feeble pulse,

lying on the back and sinking down toward the foot of the bed, with

suppression of urine.

[Footnote 40: Incidentally, it may be mentioned that the return of the

pulse to its normal rate is often considerably delayed in

convalescence from typhus and typhoid fevers and other protracted

diseases. If, then, the temperature is not above 99° F., and is stable

from morning to night, the tongue is clean and moist, and appetite

begins to appear, we need not be alarmed, although the pulse continues

as high as 90 or 100 per minute, in a case attended by positive

debility.]

In typhoid fever many of the good and bad signs are the same as in

typhus, belonging to closely similar general conditions. But in

typhoid fever we observe also as favorable signs the lessening of

tympanites, more nearly natural fecal stools, and the absence of

tenderness in any part of the abdomen. As unfavorable, increase of

tympanites and diarrhoea, sometimes large hemorrhages from the bowels;

worst of all, at a late stage, sudden increase of abdominal

distension, with dulness on percussion, coldness of the skin, great

rapidity and feebleness of the pulse following perforation of the

bowel, resulting usually in fatal peritonitis.

In scarlet fever, measles, and small-pox it is a favorable sign for

the eruption to come out well at the usual time; its sudden recession

threatens malignancy. In small-pox a confluent eruption marks a

dangerous case, and so does the occurrence of distinct pustules in the

throat. Early in scarlet fever stupor is very threatening, though not

necessarily mortal. Late in the same disease bloody urine, or, worse

yet, suppression of urine, may well cause alarm.

In all children's diseases the early occurrence of convulsions shows a

{172} severe but not always a dangerous attack. The late occurrence of

convulsions is commonly much more serious in its significance.[41]

Convulsions are always of vastly less importance, prognostically, in

children than in adolescents or adults. Yet they are always serious

signs. While recovered from in the large majority of cases, they may

at any time be fatal.

[Footnote 41: Yet I saw a case of acute cerebro-meningitis, in a girl

ten years of age, in which a violent convulsion occurred on about the

sixth day of the disease, and was followed by convalescence.]

These enumerations, selected as examples merely, might be much farther

extended but that the special prognosis of each disease will be fully

set forth in the several articles upon them in the body of this work.

Those now given may suffice for the illustration of the method and

general principles by which the physician must be guided in his

anticipation of the progress and result of cases of disease. The

caution may be repeated, to observe great care in forming a conclusion

in regard to prognosis in every instance, and still more in expressing

it, unless in the presence of very clear and positive evidence.

{173}

HYGIENE.

BY JOHN S. BILLINGS, M.D.

The purpose of this paper is to indicate some of the ways in which

hygiene, both private and public, is connected with the duties of the

general practitioner, and to give some information as to modern

methods of investigation and work in preventive medicine.

While the business of the physician is more especially the care of the

sick with reference to the cure of disease, or, where that is beyond

his power, as is too frequently the case, to relieve suffering and

secure temporary ease for his patient, he is nevertheless often called

upon to answer questions as to the causes of disease, and the best

means of avoiding or destroying these causes. Not only does diagnosis

often turn upon considerations of etiology, but a very considerable

part of the treatment of actual disease must be hygienic in the

broader sense of the word. The prescription or the surgical operation

must not only be supplemented by advice as to residence, clothing,

food, exercise, etc., but must, in many cases, be merely supplementary

to such advice, which indicates the really essential method of

treatment; and the giving this advice then becomes the most important

part of the physician's work, although not usually recognized as such

by his patients. The chief value of the prescription is, in fact,

often to methodize the mode of life of the patient and to remind him

at frequently recurring intervals of the regimen which has been

ordered with it.

The physician has also certain duties in relation to the public at

large, as well as to his individual patients, and these duties become

more numerous and important as the density of population increases, so

that in the large cities of most civilized countries he finds himself,

nolens volens, in almost daily contact with legally constituted

authorities in the shape of registrars, health officers, coroners,

etc., and is not infrequently summoned before the courts as a supposed

expert in matters connected with the public health.

Moreover, the physician who has become eminent in his profession is,

in many cases the adviser, and, so far as professional subjects are

concerned, to a great extent the guide, of those who legislate for, or

execute the laws of, not only his own city or county, but his state

and the nation; and he must to a corresponding degree be held

responsible for the position which he takes and the advice which he

gives in regard to public health matters. This is true whether his

attitude on these subjects {174} be active or passive, for his silence

will be taken to mean that there is no necessity for action or change.

The limits of this paper do not permit the presentation of proofs and

illustrations of these somewhat dogmatic assertions, but it is

believed that they will meet with general assent from medical men

without formal and detailed argument, and that it is unnecessary here

to urge the interest or importance of practical hygiene upon the

medical profession, or to enlarge upon the desirability that the

practitioner, as well as the professional sanitarian, should be

familiar with the conclusions of modern science and technology with

regard to it.

In the minds of many intelligent and thoughtful physicians there is,

no doubt, a feeling of unformulated distrust as to the real

possibilities or probabilities of improving the health and diminishing

the mortality of the community at large; and this feeling is in part

due to the exaggerated claims and emotional exhortations of some

advocates of hygiene. A careful and unprejudiced survey of what has

been accomplished by sanitary measures will, however, largely

dissipate this distrust.

The natural term of the life of man is fixed by the physiologist at

about one hundred years, which is nearly in accordance with the law

indicated by Flourens, that the period of life of an animal is about

five times that required to perfect the development of its skeleton

and unite the epiphyses with the shafts of the long bones. The actual

average duration of human life is less than half this, but there is

satisfactory evidence that it has increased in civilized countries.

The ancient estimate is expressed in David's declaration, that "the

days of a man are threescore years and ten, and if by reason of

strength they be fourscore years, yet is their strength labor and

sorrow." Kolb, a cautious and learned statistician, concluded, from

his studies, that while the maximum age reached by man has not

materially changed for many centuries, the number of persons who now

survive infancy and of those who reach a ripe old age has decidedly

increased; and this opinion is sustained by Mr. Lewis, the secretary

of the Chamber of Life Insurance of New York, who points out that

while civilization largely interferes with the laws of evolution by

survivorship, it aids by economizing the waste which occurs in its

absence. "Under natural selection, when variations in capacity arise,

thousands of them are wasted where one is secured, fixed, and

transmitted. But human society economizes much of this waste, fastens

upon and improves an immensely larger proportion of the capacities

lavishly produced by Nature, and thus concentrates forces which would

otherwise spread their operation over countless ages."[1]

[Footnote 1: "Influence of Civilization on the Duration of Life,"

_Reports Am. Pub. Health Ass'n_, N.Y., 1877, vol. iii. p. 173.]

We have, however, no record of the duration of life in ancient Greece

and Rome, and it is quite possible that it was greater than in Western

Europe during the Middle Ages, which formed a period of retrogression

in a sanitary point of view. The Jew, the Greek, and the Roman, prior

to the Christian era, were probably cleaner in person and in dwellings

than the people of the time when dirt became the odor of sanctity.

In the absence of reliable data for this country, it is impossible to

speak with certainty of the results of attempts made here to prevent

disease and death. Each sex, race, and age has its own rate of

mortality, {175} and until this rate is determined we can only guess

as to whether good work is being done or not.

We can never hope to diminish the total number of deaths which will

occur in long periods, say two hundred years, but we may rationally

try to prolong the average duration of life, to diminish infant

mortality, and to secure greater comfort and better health for

individuals and for the community at large.

The reader must remember that only a mere outline of the subject can

be presented here; the details would require several volumes, and the

tendency to specialization in this, as in other branches, is so great

that it is hardly to be expected that any one man shall have either

the theoretical or the practical knowledge necessary for covering the

entire field. There are certain things in relation to hygiene which

every physician should know; there are many other things with regard

to which it is sufficient if he knows where to find full and reliable

information when he needs it. With this preface we will pass at once

to our subject, which may be conveniently divided as follows:

I. Causes of disease, means of discovery, and prevention.

II. Personal hygiene in its relations to the practice of medicine.

III. Public hygiene in its relations to physicians.

I. Causes of Disease, Means of Discovery, and Prevention.

Although the origin of disease has from the earliest times been the

subject of study by medical men, the physician has not heretofore,

usually, been called upon to investigate the causes of disease in

particular localities, until the occurrence of sickness in that

locality has called attention to the matter. The education of the

public as to the importance of sanitary work has, however, recently

made great progress, and it is now not unusual to ask the opinion of

the family physician as to the healthfulness of a given locality or

house. The question may be presented in three different ways: First.

In a given case of disease, what is the probable cause? Second. Given

the presence of a known or suspected cause of disease, what are the

best means of avoiding or destroying it? Third. In the absence of

cases of disease, to determine whether causes of disease are probably

present, and if so, what causes.

The word "cause" is here used in its widest sense, including not only

what are commonly called predisposing and exciting causes, but also

those conditions which aggravate or continue the disease. These causes

may be roughly classed as follows: Heredity; impure air; impure water;

climate; habitations; occupation; food; intemperance of various kinds;

clothing; errors in exercise; sexual errors; parasites; contagia;

expectant attention and other mental causes, including worry, etc. In

most cases two or more of these classes of causes are combined in

action for the production of a given case or outbreak of disease, and

when we refer any disease to a single factor, what is meant usually

is, not that this is the sole and exclusive cause, but that it is the

most prominent one.

Bearing this in mind, let us consider briefly some of the causes above

mentioned.

I. HEREDITY.--That the child inherits from its parents its physical

{176} type, including color, stature, physiognomy, temperament, and

certain peculiarities of structure or arrangement of internal organs,

is well known. This hereditary influence is stronger from the

immediate than from the remote ancestry, although the curious

phenomena of atavism sometimes form exceptions to this rule. The

hereditary causes of disease can be guarded against when known.

Theoretically, by preventing generation on the part of persons who are

unfit to produce offspring; practically, to a certain extent, by

taking special precautions against these causes and their effects in

the individual, particularly at those ages in which these influences

seem to have their greatest force. The most important of these

hereditary diseases are syphilis, consumption, scrofula, cancer, gout,

certain skin diseases, insanity, and criminal tendencies of various

kinds.

The physician's advice is rarely asked with regard to the propriety,

from a sanitary point of view, of a proposed marriage, nor is it often

taken when given, unless, indeed, it happens to correspond with the

wishes of the recipient; nevertheless, he is occasionally in a

position to exert influence in such a matter, and when this is the

case the following general rules may be borne in mind: 1. No marriage

should occur between persons having the same hereditary tendency to

disease; and this is especially important in marriages between

relatives. 2. A girl should not marry under the age of twenty. 3. A

person affected with hereditary or well-marked constitutional

syphilis, or having a strong consumptive taint, or tendency to mental

unsoundness, should not marry at all.

The precautions to be taken in individual cases in which there is a

known hereditary predisposition to certain diseases will probably be

indicated in the articles upon those special diseases. The most

important of these, from the sanitary point of view, are consumption

and gout, partly because of their frequency, partly because of the

undoubted power which a proper regimen, applied in time, has in

controlling them. The pain in gout has often an excellent sanitary

effect; it is an inducement to temperance much stronger than any

amount of good advice.

The influence of heredity in producing abnormities of refraction and

accommodation of the eye, and the importance of detecting these early

and giving them proper treatment, have not hitherto received, from the

general practitioner, the attention which they deserve. Children of

parents affected with astigmatism, ametropia, etc. should be carefully

examined before being placed at school, and if necessary fitted with

proper glasses.

The heredity of idiosyncrasies as to certain articles of food or

certain drugs must also be borne in mind by the physician, for,

although implicit confidence is not always to be placed in the

statement of a patient that he cannot take a certain medicine, yet a

knowledge of the facts will occasionally save the prescriber from some

awkward mistakes.

The importance of bearing in mind the family peculiarities is best

appreciated by the old family doctor who has had two or three

generations pass under his hands: he knows, for example, that in one

family he may expect brain complications, in another lung troubles,

and that what would be grave symptoms in one house are of

comparatively small import in another. Unfortunately, the greater part

of this kind of knowledge has not yet been formulated, and each

physician has to acquire it for himself; but he will find the process

of acquisition greatly facilitated if in all cases in a new family he

makes it a rule to learn something of the medical {177} history of the

parents, and he will find intelligent laymen quick to appreciate his

inquiries in this direction.

The importance of taking into account hereditary influences is well

illustrated by the care which is taken to obtain information with

regard to them in well-conducted life insurance companies. The medical

examiners of such companies have their attention specially called to

this matter, and the following extract from a manual of instructions

shows how it is regarded from a business point of view: "If

consumption is found to have occurred in the family of the applicant,

he is to be regarded not insurable under the following circumstances,

viz.:

YEARS OF AGE.

If in both parents, not insurable until . . . . . . . . . 40

If in one parent, not insurable until . . . . . . . . . . 30

(Except for ten-year endowments, then 20 years.)

If in two members (not parents) . . . . . . . . . . . . . 35

If in one member (brother or sister) . . . . . . . . . . 20

(Except for ten-year endowments, when peculiarly favorable.)"

If apoplexy, paralysis, or heart disease is found to have occurred in

any two members of the applicant's family, he is to be regarded as

insurable only upon the endowment plan, the term of insurance to

expire prior to his reaching the age of fifty years. If insanity shall

have so occurred (in two members), a provisionary clause is essential,

and is attached to the policy by the company.

II. IMPURE AIR.--The dangers of impure air, water, and food depend

largely upon the fact that through these media may be introduced into

the body particles of organic matter, living or dead, which tend to

produce disease in the recipient. The parasites are types of this mode

of disease-production, and these blend with the contagia of the

specific diseases in such a way that it is not easy to draw the

distinction in all cases. There are also certain poisonous gases and

inorganic compounds which may occasionally be present in air or water

to such an extent as to produce disease; but as a rule the gaseous

impurities of the air are offensive to the smell rather than

dangerous, as will be seen when we come to consider the effluvium

nuisances.

The subject of ventilation, for the purpose of procuring an adequate

supply of pure air, is one of so much importance, and one upon which

the physician is so liable to be called for practical advice, that it

seems proper to state briefly the general principles which should

govern investigations into, or recommendations upon, this subject.

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