Placing the patient in an entirely healthy atmosphere is next in

importance. In the very earliest stage quiet, recreation, change of

scene, and association with a pleasant and judicious companion are

often sufficient to effect a cure. If the disease is pronounced, rest

and removal from sources of irritation are more important until

convalescence, when travel may be tried. The question of removal from

home and commitment to an asylum {160} should be decided upon the

grounds already stated in considering the general treatment of mental

diseases. The degree in which the patient should have exercise,

occupation, and recreation or be let alone will be determined for each

individual case. The fact should be borne in mind that the disease is

a debilitating one, and that it arises in conditions of mental or

physical exhaustion. Massage and a modified rest-cure, without

seclusion, are beneficial in some cases, especially of elderly people.

Baths and the cold pack should be used with discrimination.

Electricity, where it does not give rise or add to delusions, is a

useful tonic, especially in passive cases. There are very few patients

of such desperate frenzy as to require confinement of the hands, and

that should only be done with an attendant close at hand. Whatever is

done, nothing should be attempted which excites delusions unless it be

absolutely necessary. Fresh air, and an abundance of it, are very

important. Experience and careful study of the particular case will be

needed to know how far to press the taking of food. But the necessary

amount should be given by the stomach-tube if ordinary means fail, and

it is better to use it early rather than tire the patient out with

ineffectual attempts with spoons, etc. Whether the nasal or œsophageal

tube be used—of which I prefer the latter—the greatest care should be

taken not to inject food into the lungs, the throat being so devoid of

sensitiveness sometimes that the tube may be passed into the trachea.

Nutrient enemata may be relied upon for a week or two if the patient

is in bed, but no longer.

Tonics are indicated—cod-liver oil with bark, the hypophosphites,

dilute phosphoric acid, malt. Strychnia, iron, and quinine should be

used with caution, as they often cause disagreeable headache with

indisposition to sleep. Fattening food will be found useful in most

cases. The few fat melancholies need nitrogenous food and graduated

exercise. Constipation will be corrected in many cases by a full,

laxative diet, cod-liver oil, malt, or it may be beer. Mineral water

or Sprudel salts are usually indicated. A pill containing aloin,

strychnia, belladonna, mastich, or even colocynth or podophyllin, may

be needed in obstinate constipation.

Medicines to control restlessness and sleeplessness should be avoided

if possible. Hydrate of chloral, opium, bromides, valerian, sometimes

increase the difficulty, and the objections to their prolonged use are

obvious, and yet they must sometimes be used for a time. The bromides,

with cannabis indica, valerianate of zinc, camphor, and hyoscyamus,

may serve an excellent purpose for a time. Opium and its preparations,

where they agree, act like magic in producing mental calm and sleep.

They may relieve constipation and increase the desire for food, but

the danger of the opium habit is so great that their use should be

decided upon only in extreme cases, and the effect should be watched

from dose to dose, each one of which should be given under medical

direction. Wilful masturbation, one of the signs of loss of

self-control which occurs in the best of people, cannot be corrected

by drugs or appliances, but only by constant watching and by placing

the individual where his self-respect, as soon as it can be appealed

to, will keep him from it. If it is uncontrollable and symptomatic,

fresh air and exercise, and, if necessary, bromides or opiates in

moderate doses, with a tonic (not iron), should be used.

{161} MANIA (Manie, Exaltation générale), according to Morel, meant,

in the original Greek, folie or madness, while Esquirol derives it

from the Greek word meaning moon, making the words maniac and lunatic

equivalent. The word mania is still used in this loose way, even by

writers on mental disease, as a synonym of insanity. Its use is

properly restricted to conditions of mental exhilaration or excitement

with motor activity. The morbid anatomy of the disease is not yet made

out, and the indications of hyperæmia observed in the acute stage

after death are no greater than are found in diseases in which mania

is not a symptom. In its final stages atrophic, degenerative, and

inflammatory signs are abundant and well marked.

Simple mania[18] (manie sans délire, manie raisonnante), an exaltation

of the mental faculties similar to the exhilaration produced by too

much wine, with an accelerated flow of ideas, impaired judgment, and

motor activity, without definite delusions, delirium, or incoherence,

has been called an insanity of action, affective insanity, folie

raisonnante, and even moral insanity, from which it differs in being

marked by constant mental elation and exaltation of the physical

functions, and not necessarily by striking moral perversion. It is a

mental erethism, an exaggerated gayety, an uncontrollable

exhilaration, an unbounded joy, an excessive anxiety, a perpetual

anger, unusually good spirits, increased intellectual and physical

energy, with such striking loss of self-control, diminished powers of

reflection, and so decided weakening of the judgment that all sorts of

unwonted errors of commission or omission may be performed. Under its

influence many fortunes have been lost, many reputations have been

ruined, and the happiness of many families has been sacrificed before

the existence of insanity was suspected, except possibly by a very few

persons. Indeed, the wit is usually so sharpened, the flow of ideas

often so clear and rapid, the capacity for brain- and body-work

without fatigue is generally so increased, that not seldom the patient

is remarked upon as being unusually well. The most troublesome

symptoms arise from the tendency to squander property, to drink

alcoholic liquors to excess, and, especially in women, to allow the

exalted sexual desires to get control of the judgment and reason,

thereby bringing about unfortunate marriages or scandalous relations

with the opposite sex. In women there is commonly increased menstrual

flow.

[Footnote 18: Also called by some writers moral insanity, folie

morale, folie des actes, folie or manie instinctive.]

The course of the disease is without material change, and the duration

is from several weeks to a number of years. When it does not

constitute the initial stage of other types of mental disease,

especially severer forms of mania, circular insanity, general

paralysis, or (in the neuropathic constitutions and at the critical

ages) mental degeneration, the termination is in recovery in about 90

per cent. of the cases, although sometimes some moral impairment or

deterioration in character remains for life. The recklessness incident

to the disease leads to unusual risks, now and then to fatal

accidents. Simple mania rarely becomes chronic.

TREATMENT involves the necessity of proper control to prevent

scandals, disasters, and perhaps crimes. The matter of the degree of

seclusion and control should be governed by the general considerations

already mentioned in the general treatment of insanity, bearing in

mind that {162} repression of the motor energy, except to prevent

exhaustion, does harm. The demand for food is enormous; its supply

should be abundant and judiciously chosen with reference to easy

digestion. Frequent prolonged warm baths and cool applications to the

head are indicated, and the usual palliatives for headache,

sleeplessness, constipation, etc. The surroundings should be such as

to favor rest and undisturbed sleep, and to dispel sources of

excitement, whether they arise in certain associations, localities,

occupations, or persons.

Acute mania (Tobsucht) follows an incubative stage of simple

melancholia, often of simple mania, and rarely bursts out without

previous indications of disease. Delusions, unsystematized and

illogical, are abundant; the ideas flow so rapidly that the mechanism

of speech is not adequate to their expression; the motor excitement is

intense. In the most severe forms there is mental confusion, delirium,

incoherence of ideas, and furious muscular action, to the point often

of acts of destructiveness and self-injury. The clothing is torn to

shreds, and no act of violence is too wild not to be attempted without

warning. The skin is hot, the tongue heavily coated, the pulse

accelerated, the temperature elevated, more, probably, than would be

accounted for by the physical activity—from one to two or three

degrees—now and then, in conditions of exhaustion, a little below the

normal. Just as there is liable to be maniacal frenzy in the course of

severe melancholia, so in acute mania outbursts are seen of

desperately suicidal melancholic frenzy. Unless great care is used to

keep up the strength, and often in spite of it, exhaustion rapidly

sets in, under the influence of which the symptoms are very much

aggravated. The amenorrhœa in women in this condition is conservative.

The COURSE AND DURATION of acute mania vary within wide limits, with

an average of not far from six months, with recoveries in about 60 per

cent. of first cases uncomplicated by pneumonia, chronic disease, or a

marked neuropathic state: 5 or 6 per cent. die, chiefly from

pneumonia, phthisis, accidents, or exhaustion, seldom suicide.

Incurable cases drop slowly into dementia or into chronic delusional

insanity, the motor excitement subsiding. The delusional insanity may

be simply a stage in the process toward dementia.

In the DIAGNOSIS of acute mania, unless great care is used, the

physician sometimes finds that he has sent to the asylum a case of

acute, especially infectious disease, in the early stage and with

unusual manifestations of febrile delirium. The indications for

avoiding this unfortunate mistake are care and time in making

diagnoses.

In the TREATMENT of acute mania the matter of foremost importance is

that the physician should be able to sufficiently control his patient

to prevent harm, and that he should have him in such a place as to

give him an abundance of fresh air, unhampered by annoying and

irritating limitations of his free will, restrictions of his liberty,

and repression of his motor excitement. The risks of injury to others

must be reasonably provided against. It goes without saying that few

homes meet these indications: very few people can command a house to

be converted into a virtual hospital, with the care of trained

physicians to direct every little detail of treatment, and proper

nursing. The public asylum, therefore, or the private retreat must

usually be depended upon. In the case {163} of quiet young people,

especially of young women whose illness may be of such a nature as to

justify their marrying after recovery, and in the acute mania

following childbirth, it is well worth the physician's while to make

an effort to keep the patient in a private house when the conditions

are such as to make such a course practicable. To the rest and quiet

which may be had under such circumstances, with all the goings on of

the house regulated to the patient's comfort and convenience, to

prolonged hot baths, a full simple diet, given with the stomach-tube

if necessary, as few medicines as can be got on with, the supervision

of the nurses by some judicious member of the family, and the

gentleness (combined, of course, with proper firmness) of

home-influences, I attach very great importance in properly selected

cases. But I attribute as much to the restful influence of keeping the

patients among familiar scenes, and where some familiar face and voice

can reassure them in their comparatively clear moments, instead of

their being agitated and distressed to know how to account for the

strange people and cell-like room of the insane ward to which they

will awaken from their delirium in the hospital. It is something to

avoid the excitement of commitment and removal to an asylum, with all

that they involve, as well as the sight of demented patients, whose

noise may make sleep impossible just when it is most needed. Acute

mania seems to me to arise much less often than other mental diseases

in definite associations which need to be escaped from for successful

treatment.

The term subacute mania is used by some writers for the milder cases

of acute mania, just as acute delirious mania is a term which is

applied to those violent cases of acute mania in which furious and

prolonged delirium marks the disease, and in which there is a high

death-rate and low proportion of recoveries.

In chronic mania the motor excitement, mental instability, and, sooner

or later, delusions, if not present at the beginning, as is usual,

continue. The progress to dementia is commonly slow, and there are few

cases which it is wise to treat away from an asylum or its

dependencies on account of the possible danger to others from sudden

exacerbations of the disease or through uncontrolled violent impulses.

Although there is no pathological condition distinctive of mania in

its curable stage, conditions indicating hyperæmia are usually found,

whether as a result of the disease or its underlying cause, and

sometimes meningitis. In chronic mania there is in the terminal stages

evidence of atrophic and degenerative changes which do not distinguish

it from other forms of mental disease.

ACUTE DELIRIUM is the typhomania of Bell. Its prevailing mental state

is of mania oftener than of melancholia. It resembles the worst cases

of typhoid fever so closely, and it is so uncommon a form of disease,

that the mistake has often been made of sending typhoid-fever patients

to insane asylums. The mistake is unnecessary, as the clinical

features of typhoid fever are so well marked that with sufficient care

and delay they may be recognized if the physician does not commit the

common error in mania of being too much afraid of his patient to

examine him thoroughly. The tendency to exhaustion in acute delirium

is rarely successfully combated, as the motor excitement is so intense

and the delirium so furious that nourishment to meet the tremendous

demands of the {164} system can seldom be given, and death is the

usual result. Recoveries are rare, but less uncommon in the

melancholic than in the maniacal form.

Little need be said in the way of TREATMENT, except that in so

speedily fatal a disease it is well to keep the patient at home, if he

can be properly cared for there.

TRANSITORY INSANITY is used by Krafft-Ebing[19] (Transitorisches

Irresein) as indicating mental disease differing from other insanity

only in the fact that it is of short duration—namely, from two to six

days. If it is applied to sudden and transient outbursts of mania,

with delirium, loss of power of self-control, and inability to clearly

recollect the circumstances of the attack and what happened during its

continuance, it is a rare disease, occurring for the most part in

epileptics and in persons under the influence of alcohol or addicted

to its habitual use. It is sometimes, under the latter-named

condition, called alcoholic trance. It consists in an automatic state

resembling the epileptic delirium, which may occur also in sleep and

resemble somnambulism. The actions are guided by co-ordinated will

without conscious intelligence, and may consist in crimes and

brutalities and foolishness entirely inconsistent with the character

in health. It seldom lasts more than a few hours. When caused by

alcohol or as a symptom of epilepsy, it may occur without other marked

inciting cause; otherwise it is commonly due to mental shock. Several

cases happened during the mental excitement of the first battle in our

civil war. The most striking case within my own experience was that of

a man who under the strain of prolonged grief and the mental shock of

a great fire destroying a large part of the town in which he lived,

perhaps moderately affected by alcohol, suddenly grasped an axe and

cut off with one blow the head of a beloved child. He was found in the

street without knowing how he had got there or what he had done.

[Footnote 19: _Irrenfreund_, 1883, p. 113.]

One attack is the rule, although several, probably of an epileptic

nature, have been reported. It is an extremely difficult condition to

diagnosticate with certainty, and is therefore often the refuge of

criminals and a resource of criminal lawyers. The most likely honest

mistake liable to be made regarding it is to confound it with an

outburst of passion.

PRIMARY DEMENTIA (Acute dementia, Stuporous insanity, Anergic stupor)

is a disease chiefly of youth and early maturity in persons of

inherited weakness or under the influence of prolonged exhausting

conditions, to which some mental shock usually adds the immediate

cause. Although most of the cases are under the age of twenty-five, it

occurs up to forty-five. Masturbation is so common a symptom in its

course—and it may be one of the debilitating and enervating factors

constituting a predisposing cause—that most of the primary dementia is

classed in some asylums as insanity of masturbation. There may be an

initial stage of a number of days, marked by moderate melancholia or

by maniacal excitement, but there is usually mental torpor advancing

rapidly to pronounced dementia. In rare cases there is marked chorea,

and slight choreic movements are often observed. The course of primary

dementia may be subacute and advance with extreme slowness.

There is no overwhelming delusion paralyzing the mind, so to speak, as

in melancholia attonita (melancholia with stupor). In acute cases the

brain quickly falls into a state of profound anæmia, precisely such as

is {165} found post-mortem in starved dogs, and loses its power to a

greater or less extent of reacting to the stimulus of the senses.

There is little or no sensation of hunger, the sensory nerves are

nearly or quite paralyzed, the bladder and rectum become distended

until urine and feces are voided unconsciously or at least

uncontrolled, and voluntary movements almost cease, although the

muscles are capable of acting if directed: if led or pushed, the

patient walks; if placed in a chair or bed, remains there; and in the

worst cases lies on the floor quite inattentive to all the decencies

of life unless constantly looked after. There is always partial, and

there may be complete, anæsthesia, to such an extent that even the

involuntary muscles do not respond to the ordinary stimuli. There is

rapid loss of flesh, very sluggish circulation, and feeble

heart-action. After recovery the patient speaks of the stage of his

greatest illness as a blank in his memory.

This description of pronounced cases of primary dementia of the most

severe type needs modification as applied to milder cases, which may

exist in all degrees, down to a state of mental impairment of very

moderate extent.

The mental impairment may be progressive and quite incurable, but also

so slight in the beginning, and may make such slow progress, as to

entirely escape detection for several years, and then attract

attention at first by the lowered plane of character and loss of

self-control in little matters of daily life, rather than by the

intellectual deterioration, which by that time has become quite

marked. This subacute form of primary dementia in young people rarely

finds its way into the insane asylum until the second, third, or

fourth year of its course, and then its progress is slowly downward.

It has none of the eccentric or grotesque features of hebephrenia, and

little of its emotional disturbances.

Subacute primary dementia in the later years of maturity, just before

or several years before the climacteric, is of grave import, as it

indicates the development of an hereditary predisposition to insanity

in a form which not only offers no reasonable hope of recovery, but

also is quite certain to manifest a change of character which is even

more difficult to treat and properly control than the intellectual

failure. As it is most likely to arise under circumstances of wear and

worry, its symptoms may be for a long time attributed to

disappointment or bad temper. After the dementia becomes pronounced

its downward course is seldom otherwise than very rapid.

SECONDARY DEMENTIA is a convenient name for the curable dementia which

appears at the subsidence of acute symptoms occasionally in mania, and

rarely in melancholia—that is, just about the beginning of the period

of convalescence. It is also called secondary stupor.

In primary and secondary dementia, resulting in recovery, the progress

of the disease is rarely otherwise than very rapid, and unless a cure

takes place in a few months at the outside, secondary changes occur in

the brain and the tendency is to terminal or incurable dementia. So

many cases are treated outside of asylums that it is difficult to

estimate the cure-rate, but it is probably not less than 60 or 70 per

cent., although it is quite common in the apparent cures for the brain

to remain on a lower intellectual or moral plane than if the disease

had not occurred.

TREATMENT does not involve the necessity of removal from home in {166}

the acute cases, except when that is demanded for convenience of

treatment. There is no melancholia to suggest the possibility of

suicide, and no mental exhilaration or motor excitement to make

restraint necessary. The most important indications are met by

abundant, easily-assimilated food, which must usually, for a time at

least, be given with a spoon or by the stomach-tube; fresh air,

attention to the processes of digestion, relief of the

gastro-intestinal catarrh by the usual remedies, stimulating baths,

tonics, stimulants, and general galvanism. Proper care in emptying the

bladder and rectum and entire cleanliness will suggest themselves.

In mild cases a tonic and stimulating regimen, including sea-bathing

and gymnastics, will often be sufficient.

In the subacute cases young people are easily depressed by the asylum

associations, but there is usually a time in the progress of the

disease when home-discipline is too weak for them, and they must be

sent away; older people have usually complications in their home-life

such as to make a change desirable for the comfort of the household.

Recoveries are extremely exceptional.

In all cases there is little to be gained in keeping up

home-associations for so disturbing, distressing a disease after there

is pronounced dementia.

Medicines, other than tonics, are of little use, except opiates to

control various distressing nervous symptoms, including masturbation,

but they should be used with great caution.

KATATONIA (Katatonie of Kahlbaum; Katatonische Verrücktheit of Schüle)

presents, with more or less regularity of appearance, symptoms of (1)

mild melancholia without the characteristic mental pain; (2) mental

excitation, sometimes ecstatic, with cataleptiform conditions; (3)

confusion and torpor or apathy. There is an underlying well-marked

intellectual impairment, slowly advancing in incurable cases to

pronounced dementia. Delusions, more of the unsystematized than of the

systematized character, but resembling both, constitute a prominent

part of the disease from the beginning. Verbigeration and a curious

sort of pomposity are usually found in more or less pronounced degree.

The delusions are mixed. They are exalted, hypochondriacal,

melancholic, with all sorts of self-accusation, and may be full of

suspicion, fears of poisoning, and ideas of persecution.

Hallucinations of the special senses and illusions are not uncommon.

If the term katatonia is not used, or at least if a special place in

the nosology were not given this disease, it would be difficult to

know whether to class these cases as primary dementia, melancholia

with delusions, delusional insanity, or confusional insanity.

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