The states of mental defect and degeneration, except in the case of

idiocy or marked imbecility, are not associated with such obvious

physical evidences of deviation from a normal mental standard as to

make them pathognomonic. While asymmetry and other cerebral defects

are frequently observed in them, it must be acknowledged with Schüle

that similar and as extensive gross intracranial anomalies are found

in persons who could not be called of unsound mind, and that this

statement holds true even of primary insanity, in which some writers

have laid so much stress upon the value of any indication of imperfect

or asymmetrical cerebral development. Any defect in the brain,

however, is far more common among persons of unsound mind than among

those of sound mind, and therefore in doubtful cases it is of a

certain value as corroborative evidence of mental infirmity or

impairment.

Spitzka places as signs of the insane constitution (1) atypical

asymmetry of the cerebral hemispheres as regards bulk; (2) atypical

asymmetry in the gyral development; (3) persistence of embryonic

features in the gyral arrangement; (4) defective development of the

great interhemispheric commissure; (5) irregular and defective

development of the great ganglia and of the conducting tracts; (6)

anomalies in the development of the minute elements of the brain; (7)

abnormal arrangement of the cerebral vascular channels,—at the same

time acknowledging that there are cases of insanity of inherited

origin in which cerebral defects are not discernible. It is too early

to estimate the value and importance of the finer or qualitative

cerebral defects as giving rise to insanity. Benedikt finds them also

in criminals.

With regard to responsibility before the law, the statutes of no

country provide for any criterion by which accountability is defined

in these cases; medical witnesses differ in opinion as to their

criminality, and the courts are obliged to interpret the law to suit

individual cases.

The states of mental defect and degeneration are not sharply defined.

They run more or less into one another. The fact should also be kept

in mind that isolated symptoms and groups of symptoms belonging to

them are repeatedly found in curable conditions of physical and mental

exhaustion in neurotic persons.

The degenerative mental states are thought to be increasing, to

furnish material for the increase in the otherwise curable insanities,

and to thus include much of that portion of the community which is

most filling up our institutions with incurable cases. It is probably

in the prevention of them, or at least in the proper training and

disposition of children affected with them or predisposed to them,

that the most can be done to stay the increase of insanity. Perhaps at

some time unwise marriages of passion and sentiment will be less

common than now, and the rights of children to a fair start in life

more considered.

Psychoneuroses.

AFFECTIVE MENTAL DISEASE is a folie raisonnante, one of the reasoning

insanities, sometimes called moral insanity, and very like the moral

{154} insanity already described, except in the absence of signs of

mental degeneration and in the fact that it is a curable disorder. It

is an insanity of action, marked by scarcely noticeable mental

impairment. It often is the early stage of more serious mental

disease, and not seldom its symptoms remain, as simply change of

character, after the striking symptoms of extensive mental disorder

have disappeared. It also exists and is cured without the appearance

of more pronounced insanity. At the time of the climacteric it is a

form of mental disorder not uncommon among women, who, however,

usually fail to recognize it as such until they have recovered.

Maudsley includes under this head simple melancholia, simple mania,

and moral alienation, but it will be more convenient for the present

purpose to use the term affective mental disease as indicating a

curable moral alienation or change of character affecting the

intellect chiefly so far as the judgment and sense of propriety only

are concerned, and not dependent upon constitutional defect or

developed degenerative mental state. There is usually slight

exhilaration or depression, which alternates or varies from time to

time.

The PROGNOSIS is favorable.

The TREATMENT is brain-nutrition, with those general measures already

described.

HYPOCHONDRIASIS, as Flint[17] well says, belongs in the list of

disorders of the mind, although the mental alienation is not regarded

as amounting to insanity. The mental state is one of morbid

imagination and apprehension rather than of definite delusion, and it

consists in a belief in the existence, present or to come, of maladies

and diseased conditions for which there is no foundation in fact, in

spite of sufficient proof of their unreality. There is usually, not

always, mental depression. Its causes lie in conditions, usually

obscure, which lower the tone of the general health, including

hereditary weaknesses, or depress the vitality of the brain either by

physical wear or mental worry, and the exhausting influence of

functional disorders or of organic diseases which may not be

discovered before the autopsy. Disappointment, bad habits, want of

proper mental occupation are often at fault.

[Footnote 17: _Practice of Medicine_, p. 854.]

The physical symptoms of hypochondriasis are commonly those associated

with impaired digestion and nutrition—namely, anæmia, dyspepsia,

neurasthenia, constipation, flatulence, headache or a feeling of

discomfort after using the brain, less appetite, slight loss of flesh,

disordered sleep.

The mental indications are more or less melancholy, indisposition to

exertion, irritability, diminished power of self-control, and an

inability to cease except temporarily from interpreting signs, proved

to be trivial, as indicating grave maladies or as forewarnings of

severe disease to come. Sometimes the fixed idea is limited to a

single false conception, but oftener slight changes in physical

symptoms or differing phases of morbid introspection produce a

complete kaleidoscope of pictures of fancied misery. The whole

catalogue of diseases, or a large part of it, may be exhausted, with

the help of some of the many foolish treatises always ready for

hypochondriacs or from reading medical books and talking with

charlatans, who are consulted at rapid intervals, one after another,

both by those who wander from office to office and those who take to

their beds. The most common type of hypochondriasis arises, directly

or indirectly, {155} in some form of unhealthy or false ideas

regarding the sexual function, and in the idea that some imagined or

exaggerated abuse of it has produced or will produce most serious

evils; but there is not an organ of the body which may not be the

basis for the unwholesome thoughts. Not seldom there is simply the

delusion of especial weakness or sensitiveness or delicacy.

Hypochondriasis may be only the early stage of more serious mental

disease. It may be one manifestation of an hereditary neurosis or

psychoneurosis, or it may arise from deterioration of the body's

vitality by organic disease, especially of the abdominal or pelvic

organs or through some incurable weakness or functional disorder. In

either of these cases its cause and duration will be determined by the

clinical history. As an uncomplicated psychoneurosis hypochondria

lasts from a few months to a number of years, with very little change

in its prominent symptoms, resulting in recovery for the most part,

becoming chronic in a moderate proportion of cases, and rarely proving

fatal except by some accidental complication, including suicide.

The PATHOLOGY AND MORBID ANATOMY of the disease are unknown.

The differential DIAGNOSIS consists in the exclusion of other

diseases.

The PROGNOSIS is favorable in uncomplicated cases.

TREATMENT consists in measures to improve the general health,

especially a full diet carefully selected, hydro-therapeutics,

massage, gymnastics, horseback riding, walking, rowing, abundant and

agreeable exercise in the open air, and the management of the

patient's surroundings so as to lighten the mind and relieve from

worry, perhaps by travel, sea-voyages, etc. Argument is commonly worse

than useless, but there should be a decided impression given that the

generally morbid state is due to ill-health. The risk of suicide is so

small that restrictions of liberty directed to its prevention do more

harm than good. It goes without saying that bad habits should be

reformed, narcotics should be avoided, and a healthy occupation should

be encouraged, or, if possible, insisted upon. The difficulties in

treatment are fully as great with the highly-educated superstitious

and credulous people whom we find in the literary and professional

circles as in the ignorant and weak-minded.

MELANCHOLIA (Die Melancholie, Schwermuth, Tiefsinn, Trübsinn,

Lypemanie, Mélaneolie, Aliénation partielle depressive, Monomanie

triste, Phrenalgie, Psychalgia) is one of the functional mental

diseases, in the sense that the pathological condition of the brain

upon which it depends is not yet known, although it is thought to

begin with disturbances in circulation and nutrition, which end, if

not resulting in cure, in atrophic, degenerative, and inflammatory

states, indicating, in the great majority of cases, extensive brain

disease. As a rule, melancholia first appears in a slight change of

character; the patient is said by his friends to be not quite like

himself. After some days or months, as the case may be, the symptoms

develop into settled gloom associated with mental pain—the state known

as

Simple Melancholia (Mélancolie raisonnante), in which the events of

life are correctly observed, but, incorrectly interpreted, are the

source of constant apprehension, self-depreciation, depression, and

despondency. There are no delusions, properly speaking, and yet there

is a disposition to take the dark-side view even of circumstances

which promise {156} favorably, which amounts to a generally deluded

state of mind. Commonly there is increased irritability, now and then

a genuine moral insanity, and occasionally in neuropathic

constitutions the state of mind already described under the head of

Impulsive Insanity, of which the suicidal impulse is the least

infrequent. Sometimes there are no physical indications of disease,

but as a rule there are headache, increased sensibility to light and

noise, sleeplessness, restlessness, impaired appetite and digestion,

gastro-intestinal catarrh, marked loss of flesh, diminished or

abolished sexual desire, and in women usually delayed menstruation or

amenorrhœa. A few persons are able to keep up, in an irregular sort of

way, their customary employment. In the majority of cases it is

impossible to concentrate the mind upon work, mental occupation

fatigues the brain, and the physical strength is too impaired for

steady labor. Suicide is thought of probably in nearly every case, as

it is by many sane people at some time in their lives, but it is very

seldom committed unless there are such disgraceful or distressing acts

performed or suffered by them as would tempt to suicide in sane

people. There is no danger of deliberate homicidal acts in persons of

good character. A criminally disposed person would more readily commit

murder in simple melancholia than if free from that disease.

Simple melancholia may be the initial stage of almost all of the

mental diseases, especially acute mania, paralytic dementia, and the

severer forms of melancholia. It may be differentiated from the first

stage of mania only by waiting until other symptoms appear or not, and

the same is true with regard to distinguishing it from the forms of

melancholia involving danger to life. In the latter case, however,

there is much greater difficulty in diagnosis, inasmuch as insane

delusions may be concealed, and there may be so slight a change in the

patient's behavior when delusions appear in his mind that the closest

observation is needed to guard against them. The simple melancholia

marking the first stage of paralytic dementia is characterized by

noticeable although often slight mental impairment—a distinctly

diminished capacity for work, of which the individual himself is not

seldom conscious, whereas in the disease simple melancholia the mind's

usual power is exerted, provided its attention can be withdrawn from

morbid introspection and concentrated upon any subject, as it commonly

can be for a while.

Melancholia with delusions (acute melancholia) is commonly a further

development of simple melancholia, but sometimes its course is so

rapid that if there is a period of mental depression without delusion

it is overlooked. The earliest and most common delusion is some form

of causeless self-reproach with regard to some matter, whether trivial

or important, or of groundless self-accusation, of impossible sins of

omission or commission, but generally of some vague, undefinable

fault, as having irretrievably offended God or committed the

unpardonable sin, etc. Often this and an unfounded belief in

self-unworthiness are the only delusions present, and in that case

within narrowed limitations the mind acts soundly in other matters.

The feeling of personal fault or sin often expands to a sense of the

justice of punishment, and the consequent delusion that all sorts of

terrible things are to happen—poverty, the poorhouse, or some great

unknown dread, even involving family and friends; and from personal

sin or fault it is only a step to the belief {157} that the world is

all wrong, and to the certainty that everything is going to worse than

ruin. Illusions of sight and hearing may magnify common fires and

locomotive whistles into general conflagrations of the world and

shrieks of tormented persons. Hallucinations of the special senses may

create visions of all sorts of imaginary horrors, sounds of voices

saying every possible dreadful thing, odors most disagreeable, tastes

most vile. Anæsthesia prompts the delusion of death, and hyperæsthesia

of burning, freezing, scalding, etc. Some mysterious force within

them, which they can neither explain nor understand, drives them to

automatic acts of all kinds—to obscenity, profanity, verbigeration,

intonation of sentences, wailing, screaming, destructiveness, etc. In

cases of exceptional severity the mind seems deluded on almost every

subject: the food is poisoned, the atmosphere is deadly, the world

loses all its reality, friends their identity, things their substance.

They are to be burned alive, starved, quartered, suffocated,

smothered, drowned. Every conceivable and inconceivable thing is to

happen. The delusions are nearly always of the illogical or

unsystematized kind, although systematized delusions of persecution

are met, for the most part, in incurable cases. Deliberate plans of

suicide are formed in most cases, and are to be suspected in all.

Homicidal attempts are apt to be made upon persons whom it is desired

to save from impending calamities. Suicidal, and less often homicidal,

impulses occur. Suicide and homicide from deliberation need, to be

successful, (1) the opportunity, (2) lack of power of self-control,

and (3) a strong determination. Sometimes there is the will without

the opportunity, or the opportunity with self-control; and for this

reason persons in danger of killing themselves or others often for

months escape any acts of violence. Not seldom, too, they determine to

kill themselves or family in a particular way, and neglect other

chances so long that they are thought to be not meditating destruction

of self or others. When the determination or impulse to suicide or

homicide is persistent and desperate, no means are too horrible and no

opportunities too hopeless to be attempted. There is no reason for a

special name for these symptoms, but they have been called suicidal

melancholia and homicidal melancholia. No more is there any

justification of the term hypochondriacal melancholia for melancholia

with hypochondriacal symptoms.

In melancholia with delusions there is sooner or later, in the

majority of cases, refusal to eat, from lack of appetite, nausea, or

disgust of food, from disagreeable hallucinations of taste or smell,

from delusions that it is a sin to eat, that the stomach is full, that

the mouth is sealed or the throat obstructed, that the food is not and

cannot be paid for, that eating will do no good, etc., from a wish to

commit suicide by starving, or in the states of stupor

(attonitäts-zustände) from mental torpor or stupidity. Sometimes there

is resistance to the calls to eat, urinate, or defecate by virtue of

resistive melancholia—a condition to resist and oppose everything—or

from delusions that it will destroy the soul, etc. to follow the

natural inclinations. Refusal of food may be under certain conditions

instinctive and conservative. It is the exception for the bodily

functions to be well performed. Usually, there is obstinate

constipation, with headache, coated tongue, greater variation in daily

temperature than is usual in health, accelerated pulse, and rapid

wasting in flesh. The various anomalous sensations observed in

functional diseases of the nervous {158} system are common.

Masturbation is a not infrequent symptom of loss of self-control in

both sexes.

Acute melancholia is sometimes confounded with delusional insanity

with mental depression. In the former the delusions are evolved from

the mental state; in the latter, the mental state from the delusions.

In the former the delusions are for the most part unsystematized: the

patient cannot state why he believes them to be true; in the latter

there is correct reasoning from false premises: the delusions are

logical or systematized and of a depressing character, so that a

belief in them naturally gives rise to sadness.

Before the courts the fact should be kept in mind that persons with

acute melancholia have diminished power of self-control by virtue of

their disease, and so yield more readily to temptation than in health.

They also may have imperative conceptions—ideas so strong that they

cannot, or can with difficulty, resist carrying them out even when

they know them to be wrong; and there may be sudden outbursts of

almost maniacal excitement. They are often able to make wills and

perform contracts, in form and in detail, as well as ever, when they

are so filled with insane delusions as to be on the point of killing

themselves and their families. There is impaired capacity, however, of

recognizing the relations of persons and things to one another, a

distinct moral perversion, and a diminished recognition of obligations

and sense of responsibility. In other words, they are not always fully

themselves on those points in which they seem to be so, and yet

patients in asylums with acute melancholia have been known to give the

best of advice to their business-partners.

Melancholia with stupor (melancholia attonita) appears like complete

dementia or a mindless state, but there are now and then evidences of

intelligence. The mind is filled with overwhelming and terrible

delusions, which paralyze the will and place mental and physical

activity for a while in abeyance. It arises commonly in the course of

the less profound form of melancholia, after some great mental shock,

and there is a condition of marked anæmia of the brain, probably

symptomatic rather than pathognomonic, which if not soon relieved goes

on rapidly to atrophy and degeneration. Except when there are attacks

of frenzy, which may occur at any time, there is little danger of

active violent acts except suicide, desperate refusal of food, and

determined resistance to any care or treatment. There are the usual

indications of physical exhaustion.

In melancholia agitata the mind is clear and active, the opposite of

the condition last described, and the distressing delusions produce

such a degree of motor excitement arising from the mental suffering

that the disease closely simulates acute mania. The mind not only

reacts as readily as in health to distressing ideas, but abandons

itself more fully to their domination through diminished will-power

and lack of self-control. Almost blind acts of desperation and fury

are committed from which the utmost vigilance can hardly save them.

The three severe forms of melancholia just described are

interchangeable in the same person during the course of his illness,

so that the states of frenzy and stupor are more properly called

symptoms than classes of disease.

Melancholia among children is more common than the books state it to

be, although rarely met in the asylums. Magnan has reported a {159}

suicidal case in a child four years old, and it occurs up to the

latest years of life.

The DURATION of simple melancholia is from a few weeks to a dozen

years; of acute melancholia, from a month to two or three years, after

which it is apt to end in chronicity; melancholia stupida (with

stupor) is usually curable, if at all, in the first year, although

relapses are frequent, and in melancholia agitata from a year to three

years is the common limit of the possibility of a cure.

The PROGNOSIS in simple melancholia is favorable. Including cases

treated out of asylums, probably 90 per cent. recover; in acute

melancholia, uncomplicated with other diseases, not far from

two-thirds recover; in melancholia attonita less than half get well;

and in melancholia agitata nominal recovery occurs perhaps in a third

of the cases, although I doubt whether complete restoration to health

is seen often.

In chronic melancholia the process of mental deterioration is slow. As

the mind becomes impaired the delusions lose their activity and the

mind reacts less readily, so that a state of less suffering and

greater calm is reached, and the patients are often useful workers in

asylums for many years, or remain in their own homes a constant source

of anxiety to those who understand their condition. Many of them

commit suicide.

In treatment of melancholia the first indication is to protect society

and the individual against acts of violence. Homicidal acts are not to

be feared in simple melancholia, unless in persons of bad character

and ugly temper, or in those few cases with the symptoms, in addition,

of moral insanity or impulsive insanity. Suicide is so rare that

precautions will not often be needed against it, provided the patient

is so frank or so transparent that the appearance of distinct

delusions may be detected and then guarded against. In cases of long

standing, especially in persons beyond middle age, this is extremely

difficult, and their treatment outside of asylums must always be

attended with risk. In the other forms of melancholia the fact should

be taken for granted that the patient is suicidal, and he may be also

homicidal, so that he should be watched constantly and efficiently,

and never left alone or with weak or helpless persons, no matter how

free from suicidal determination or impulse he may have appeared. The

puerperal mother, especially, is a source of the greatest danger to

her child, even when she seems natural and fond. The degree and kind

of watching varies, according to the severity of the case, from the

constant presence or close proximity of some responsible person, who

may sleep in the same room with the usual home-surroundings, to the

most vigilant and wakeful personal care every moment day and night,

and removal of every source of possible self-injury. In some few cases

this can be well done only in an asylum or in a padded room. Some form

of restraint, either personal or by confining or limiting the

movements of the hands in rare cases of exceptional desperation, will

be found necessary.

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