_(a)_ Osseous obstruction in the nasal chamber.

_(b)_ Membranous obstruction in the nasal chambers from compensatory

hypertrophy of the erectile tissue, alone or with

hyperplasia.

_(c)_ Obstruction arising from hypertrophy of the adenoid tissue in

the pharyngeal vault.

_(d)_ Contracture of the levator palati muscles.

SECOND VARIETY--that dependent on structural changes in the component

parts of the nasal chamber.

This variety is associated with--

_(a)_ Chronic inflammation of the nasal mucous membrane without

hypertrophy of the erectile tissue.

_(b)_ Atrophy of the turbinals and their associated mucous membrane.

_(c)_ Necrosis of the bones which enter into the framework of the

nasal chambers.

FIRST VARIETY.--Defects in nasal respiration induce hyperæmia,

distension of the erectile tissue, hyperplasia of the mucous membrane,

and {44} inevitable distress in the nose. A sense of fulness across the

bridge of the nose and at its sides is complained of. Frontal headache

may be present.

_(a, b)_ When the septum is deflected and the left nasal chamber is

narrowed, the labor of sustaining nasal respiration is thrown on the

right side. This arrangement invites a flow of blood to the already

large turbinals, and creates obstruction which is frequently referred

to the right side, although both are alike affected. Thus, subjects in

which the initial obstacle is osseous complain of distress caused by

cavernous-tissue hypertrophy of the lining membrane of the opposite

side. This represents a very common class of cases.

When the septum is not deflected, but projections from it impede the

current of air, there may be either unilateral or bilateral

obstruction, dependent upon the shape of the septum itself. Hypertrophy

of the cavernous layer of the mucous membrane usually coexists. These

cases are numerous, but less common than those last described.

Infrequently, cases are seen where the distress is occasioned by

defects of the osseous structures not accompanied by cavernous

hypertrophy.

Treatment of the above disorders consists in restoring nasal

respiration by removing obstructions, whether they be osseous or

membranous. The septal projections may be drilled or filed away, or, if

marked deflection of the anterior portion be present dependent upon a

malposition of the triangular cartilage, an operation simple in

character may be performed for its correction. This consists in

severing the connection of the lower margin of the cartilage with the

maxilla and slipping the partially free cartilage to a new position.

The details attendant upon the operation need not be here given. The

reduction of the hypertrophied membranes can be best accomplished by

cauterization. The most efficient method is by means of the electric

cautery. The electrode used should be flexible and of small size. The

points which most frequently require cauterization are the premaxillary

portion of the inferior turbinated bone, the under surface of the same,

and the septum at the maxillary spur. Rarely the inferior surface of

the inferior turbinated bone at the palatal region requires attention.

The applications are best made over small surfaces at a time, and

should be repeated at intervals of from two to three days until all

suspected points have been at least once cauterized. Not infrequently,

the effect of the cauterization at one spot will cause constriction to

take place in the vessels of the entire mucous surface, so that while

this condition lasts it is impossible to tell what additional points of

the membranous obstruction demand removal. At the following visit,

however, the vessels have become relaxed, the membranes are again

turgescent, and if obstruction now occurs it can easily be detected.

The galvano-cautery can only be used in the nasal chamber in patients

who are earnestly seeking relief and are willing to assist the

physician in all his efforts. With the tractable, intelligent subject

it can with proper care be limited exactly to the spot intended. It is

scarcely necessary to observe that any erratic or unexpected motion of

the head will sear unaffected and sensitive surfaces. The interior of

the vestibule is perhaps the most sensitive of these, and should always

be protected by the use of the nasal speculum. No additional protection

is needed, though in the judgment of others, among whom may be

mentioned E. Shurly of Detroit, Michigan, an ivory shield passed in the

nose parallel to the electrode is a necessary safeguard.

The pain of the application is generally slight, and can be in part

annulled by a previous application of a 4 per cent. solution of

cocaine. Some annoyance is acknowledged on the following day from the

pressure of the eschar. Traumatic congestion of the entire mucous

surface of the corresponding chamber is at the same time detected, and

is usually sufficiently decided to produce some of the effects of acute

coryza. This condition will spontaneously terminate in from thirty-six

to forty-eight hours. The most annoying features {45} following an

application of the galvano-cautery which has been too freely made do

not belong to the group just indicated, but rather to reflex

disturbances. Pains are occasionally excited in the teeth, in the

temple, eye, nape of the neck, and the middle ear. On one occasion in

the writer's experience a unilateral reflex excitation of the entire

opposite side of the body occurred, and a prickling sensation, followed

by numbness, ensued, which lasted for twenty-four hours. Very rarely a

congestion of the pharynx, of the larynx, and the larger bronchial

tubes ensues, which can scarcely be directly attributable to the

application, yet it has followed in a sufficient number of cases to

lead me to believe that the two are in some remote way associated.

Perhaps such a condition is analogous to the slight irritation of the

respiratory tract following excision of the tonsil. Careful use of the

galvano-cautery will obviate the conditions above described. They are

important to remember as serving as limitations to the use of this

valuable agent.

_(c)_ It will be seen that osseous obstruction in the nasal chamber and

hypertrophy of the cavernous nasal tissue often coexist. More rarely, a

third element occurs as a complication, or it may be found

independently of all other morbid processes. I allude to the presence

of hypertrophy of the adenoid tissue in the pharyngeal vault. When this

tissue is only moderately developed, it need not, and does not,

interfere with nasal respiration; but when it projects downward to such

a degree as to lie within the axis of the lower portion of the

posterior nares, it produces the same effect upon nasal breathing as

though obstruction existed within the chamber. The growths can be

easily detected, as a rule, from behind by the aid of the rhinal

mirror, but it should not be forgotten that they also can be seen from

in front, provided the chamber is free from obstruction along the

respiratory tract. In some individuals the ribbed or lobate structure

of the mass can be discerned, but more often its presence is revealed

by the minute points of light reflected from the lobules. If it be a

matter of doubt whether these points of reflection are within the nasal

chamber or beyond it in the pharyngeal vault, the patient may be

requested to swallow, or to pronounce the letter _e_; when, if the

point of reflection is within the nasal chamber, it will not change its

position, but if it be within the naso-pharynx, it will be moved

slightly from side to side, or it may for a moment disappear.

The symptoms of nasal catarrh which are provoked by the presence of

such a growth can be alone successfully treated by the removal of the

offending mass. In young individuals--say, from twelve to eighteen or

twenty years of age--the finger inserted into the naso-pharynx from

behind can often break down the growth. Slight hemorrhage follows this

procedure, and the tags of imperfectly-destroyed tissue can be

subsequently treated by caustics and powerful astringents. In the event

of the patient proving intractable, the growth may be reached from in

front through the nasal chamber, and the galvano-cautery can be used by

passing the electrode backward through the nostril until it meets with

resistance, which is invariably at the pharyngeal vault. Should this

method of treatment not be permitted by an undisciplined or nervous

person, the prolonged use of a glycerole of iodine may gradually reduce

them in size; but no definite result can be promised from such

treatment.

_(d)_ Very rarely, through inordinate elevation of the soft palate

owing to over-action of the levator palati muscles, the passage of

communication between the naso-pharynx and the oro-pharynx is

inadequate. Consequently, the nasal chamber is imperfectly ventilated,

and its secretions, not flowing backward or being displaced to the

normal extent, become semi-inspissated, and create obstruction by

lodging in the respiratory tract, either in the premaxillary or palatal

portions. To successfully combat this condition it is evident that no

local treatment is demanded, either in the nose or the naso-pharynx,

other than to increase the tonicity of the pharyngeal and palatal {46}

muscles. Very frequently in such cases there is a symmetrical atony in

the muscles last named, which demands the internal use of strychnia and

iron and the application of galvanism.

PROGNOSIS.--When nasal catarrh has proved to be dependent on defective

respiration, the removal of the causes entering into this condition may

with reason be expected to effect recovery. The prognosis, therefore,

is favorable. In young persons, in whom reparative power is present in

the highest degree, and in whom a secondary hypertrophy of the

cavernous tissues is least developed, a prompt cure may be obtained by

removal of the osseous or other forms of obstruction. In adults,

however, the prognosis is less favorable, especially with those who

have approached or passed middle life, and who have contracted vicious

habits of breathing, which are likely to persist even after the removal

of their causes. It is also tenable that in such subjects the mucous

lining of the cranio-facial sinuses has become involved. Should anosmia

persist after the capacity of the chambers has been augmented--in a

word, should this condition not be dependent upon obstruction, but upon

changes in the olfactory surfaces--the prognosis is less favorable than

in any of the cases of the above-named group.

Treatment will, however, always secure amelioration of the symptoms,

and few cases occur which cannot be greatly improved. The general

health is invariably benefited. Should a tendency to asthma exist, it

is apt to disappear, the complexion clears, and in adolescence the rate

of general development is accelerated.

SECOND VARIETY.--The group of nasal diseases included under this head

is not a natural one, since it embraces disorders characterized by a

negative feature--viz. absence of obstruction to nasal respiration.

Nevertheless, it is convenient to consider under a single head a number

of relatively infrequent disorders in which there is invariably an

underlying constitutional cause. Subjects of disorders herein embraced

are not merely sufferers from insufficient oxygenation of the tissues,

but have impaired general vitality or possess a decided constitutional

taint, whether specific or otherwise. The nasal condition is simply the

most prominent of the local manifestations.

Three distinct disorders are herein named: first, chronic inflammation

of the nasal mucous membrane; second, atrophy of the turbinals and

their associated mucous membrane; third, necrosis of the bones entering

into the framework of the nasal chambers.

_(a)_ Inflammatory thickening is a rare affection. It is more frequent

in males than in females, and in persons of a sedentary occupation than

in those who are actively employed. Those subject to it are apt to have

light-blue or gray eyes and auburn or sandy hair. On examination, the

chambers may be found free from peculiarities of bony structure,

capacious, and without hypertrophy of the cavernous tissues, yet the

membranes be of a deep-red color and of cushiony consistence, yield

bright reflexes, and the shank of the instrument introduced into the

nose is mirrored upon them. The most conspicuous alteration is not seen

on the turbinals, but on the septum. The parts are very vascular, and

the most moderate manipulation will often end in free capillary oozing.

The discharge, though moderate in quantity, is inclined to be purulent,

and resembles semi-coagulated albumen. Quite frequently, in the

examination of a neglected case, minute flecks of this modified

secretion are seen scattered over the septum and the inferior

turbinated bone. Rarely, the discharge is maintained by the presence of

a morbid growth or inflammatory products, either in the nasal chamber

or a chamber accessory to it. The discharge then appears to consist of

pure pus mixed with the normal secretion of the nose, and, thus

rendered viscid and tenacious, it excites by its presence a condition

of the lining mucous surface quite similar to that above described.

{47} Under excitement, as after an attack of coryza, the discharge

becomes more serous in character, and is occasionally of a chocolate

color from its admixture with blood. It is without odor. There is no

obstruction to respiration except during sleep, when, in aggravated

cases, mouth-breathing may be established. Thus, the patient will often

complain of an obstruction which is never present at the time of the

examination. He further complains of a sense of dryness in the nose,

with some pharyngeal irritation. The palato-pharyngeal and

palato-glossal muscles are weak and often asymmetrical; the tonsils are

small, but the adenoid tissues are generally unaffected. In a dry

atmosphere, especially if it be loaded with irritating particles, the

pharyngeal irritation is increased--a complication which is probably

due to the inspired air passing too rapidly through the capacious and

imperfectly-guarded nasal chambers and throat. Although I have

carefully searched for all indications of aural complications,

especially for the symptoms of progressive dry catarrh, I have never

detected them but in a single instance.

The prognosis is to be guarded, although a careful course of treatment

and proper care of the general health will greatly improve, if not

entirely cure, the disease.

TREATMENT.--This consists in the application of nitrate of silver,

either in strong solution or in the solid stick, to the under surface

of the inferior and middle turbinated bones, of washing the parts with

a dilute solution of carbolic acid, and of passing through the cheek

tissues a constant electrical current of a strength of from five to ten

cells. Tonics and alteratives should not be neglected, and an outdoor

life, as far as is practicable, should be enjoined. The galvano-cautery

may be used to destroy any nodules of tissue which resist other

treatment. All applications are well borne, if indeed we may not look

upon the condition of the surfaces as partially analgesic, and thus far

of unfavorable significance. It is certain that indurated tags of

oedematous and chronically inflamed mucous membrane overlying a bone,

such as the middle turbinated or the alveolar line about the necks of

the teeth, will never yield to anything but the most powerful

astringents. Upon such tissues the most concentrated solutions of

nitrate of silver are never caustic. The premaxillary portion of the

inferior turbinated bone is frequently seen hopelessly infiltrated, and

it must then be destroyed by the electro-cautery. When a discharge of a

pus-like character exists, careful search should be made for the cause.

If a tumor or foreign body be found, it should be removed, but if the

cause lie in one of the outlying spaces of the nasal chamber, it is

evident that the above treatment is palliative only.

_(b)_ In atrophy of the nasal mucous surfaces and turbinals we have, as

in the last-named group, spacious chambers, a purulent discharge,

pharyngeal irritation (in many cases), and always associated a thin and

relaxed, if not a paretic, condition of the velal muscles. These cases

might be looked upon as an advanced stage of the preceding affection,

since it may be surmised that the stage of infiltration has been

succeeded by one of atrophy. The mucous membranes are everywhere pale,

and closely bound to the underlying bony framework. The discharge is

purulent and confluent; where in contact with the air it is desiccated,

but where protected, as by crust-like surface-layers, it is semi-fluid

and tenacious. There is, consequently, no disposition for the discharge

to escape from the nose, and it accumulates until the sense of

obstruction induces the patient to remove it by artificial means. When

first seen, the nasal chambers are frequently so fully occupied with

discharge as to conceal the characteristic appearances of the mucous

surface. This prolonged retention induces incipient decomposition of

the mass, which gives rise to the odor so characteristic of this group

of cases.

The subjects of atrophic catarrh (ozæna) are never in robust health.

They are, as a rule, of spare habit, anæmic, and with family histories

which, while {48} not distinctive, indicate that the affection is, to

some degree at least, hereditary. A few cases have come under my notice

in which all the general features of atrophic catarrh were present, but

with very slight although confluent discharge, unaccompanied by fetor.

Such cases are, strictly speaking, examples of atrophic catarrh, while

they could not, under the old nomenclature, be included under the head

of ozæna.

The prognosis is unfavorable for entire recovery, but treatment

systematically pursued will make the patient entirely comfortable to

himself and others--will arrest the progress of the disease and vastly

improve the general health. As in other forms of nasal disease, should

anosmia be present the prognosis is less favorable.

[Illustration: FIG. 19. Antero-posterior section of the bones of the

face in position, showing the premaxillary portion of the floor of the

nose greatly elevated above the plane of the remaining portions. In

ozæna, as mentioned in the text, a disposition of parts may exist

similar to that delineated, and cause discharge to collect and undergo

offensive decomposition.]

TREATMENT.--The parts should be carefully cleansed--an act which, while

imperfectly accomplished by either the syringe or the douche, is, in my

judgment, best performed by the galvano-cautery. This instrument, the

one relied upon for the subsequent treatment of the case, is to be

selected for its initiation. The largest speculum which the nose will

admit being placed in position, a spiral-looped electrode is introduced

cold into the nose and held against one of the crusts. When heated it

will effect so firm an attachment to it as to enable the mass to be

withdrawn with great ease. In patients with {49} whom the palatal

portion of the floor of the nose is depressed below the level of the

maxillary a considerable quantity of discharge may lie concealed from

observation. When, after the removal of all visible crusts, the fetor

persists, it is reasonable to suppose that the palatal depression is

filled with decomposed pus and mucus. To test such a condition, the

electrode should be appropriately curved and introduced. I have been

surprised at the quantities of discharge which can in this way be

withdrawn from a locality which, as far as I know, cannot be cleansed

in any other way.

With the removal of the crust relief is at once experienced, and if the

discharge could be removed as fast as it forms the disease would not

really be a source of offence. The general health would also improve,

from the fact that an atmosphere tainted with a burden of decomposition

would no longer be breathed. But in practice this cannot be attained,

and it is imperative, after the chambers have been entirely cleansed,

to cauterize the lining membrane throughout. I have been in the habit

of beginning such cautery treatments with the middle turbinated bone,

passing thence to the inferior turbinated bone, then to the roof of the

nose in front of the sphenoidal sinus, and lastly to the septum. Small

surfaces only should be covered at a single treatment, so that it may

take a month or six weeks to finish a single series of applications.

This treatment is almost always well borne, nothing ever ensuing beyond

a slight headache or a temporary establishment of a serous discharge.

Notwithstanding that the condition in question is one of atrophy, the

reparative power of the mucous membrane remains apparently unaffected.

At all events, no danger from sloughing is to be dreaded after such

extensive destruction of tissue. The thin eschars separate within from

three days to a week, leaving a healthy mucous membrane beneath. In one

instance the cauterization had extended to a sufficient depth to expose

the bone, and yet from this denuded surface no exfoliation took place,

the parts healing rapidly and satisfactorily. No other local treatment

is relied upon for fetid atrophic catarrh than the one mentioned. No

disinfectant washes are required if the discharge is removed as

described. Should the patient be so situated as to be unable to report

regularly for its removal or treatment, a wash composed of one part of

Labarraque's solution to sixteen parts of water may be ordered with

advantage, or a solution of carbolic acid, gtt. j to fluidounce j, with

a little glycerin, may be snuffed up the nose twice a day, or

listerine, diluted one-half with water, may be used with advantage. The

general health, of course, should be cared for, and any complications

met. I have found that during the winter months arsenic and cod-liver

oil are well borne, associated with minute doses of Lugol's solution.

For adolescents earthy and the calcareous phosphates are indicated, and

for all abundant exercise and careful dieting. When the symptoms have

been relieved, the patient should be requested to report once a month,

for it is not to be expected that all symptoms will disappear, and some

point of advice can be advantageously offered at this interval.

_(c)_ Necrosis in the nasal chamber is a cause of catarrh, inasmuch as

the fragments of bone lying within the nose excite irritation and

induce discharge. I have never seen a case of this form of disease

which was not due to syphilis. The remains of syphilitic angina are apt

to be present, and the general manifestations of constitutional

syphilis are well developed. The septum is more frequently affected

than the turbinals.

Discharge due to necrosis can be readily distinguished from that

arising from any other cause by the presence of detached fragments of

denuded bone, by the characteristic fetor, and by the history of the

case.

The prognosis is favorable, for all symptoms will cease upon the

extraction of the fragments, or at least those which remain are of an

entirely different character, and are due to the resultant

imperfections of the septum, and consequent irritation arising from the

too free entrance of air into the {50} nose. I have seen in one case an

extensive tumefaction and infiltration of the tissues covering the

middle turbinated bone at the same time that the septum was breaking

down. These masses require treatment with the galvano-cautery and

astringents after the dead fragments have been removed.

A TABLE OF NASAL DISEASES GROUPED BY SYMPTOMS.

A system of practical medicine. By American authors. Vol. 3 · 第 4 / 161 段