DAVIS.

+-----------+-------+--------------------------------------------------+

| | | |

| | | Urine. |

| | | |

| Date. | Body- +-------+------+-----------+-----------+-----------+

| |weight.|Volume.| Sp. | Nitrogen. | Uric Acid.| P₂O₅. |

| | | 24 | Gr. | | | |

| | |hours. | | | | |

+-----------+-------+-------+------+-----------+-----------+-----------+

| 1903 | kilos | c.c. | | grams | gram | grams |

| | | | | | | |

| Oct. 4 | 59.3 | 2030 | 1014 | 15.15 | 0.672 | 1.99 |

| 5 | 59.3 | 1160 | 1020 | 10.99 | | |

| 6 | 59.0 | 850 | 1024 | 9.38 | 0.503 | 1.26 |

| 7 | 59.1 | 1860 | 1012 | 13.95 | | |

| 8 | 59.3 | 960 | 1021 | 9.33 | 0.398 | 1.47 |

| 9 | 58.3 | 900 | 1027 | 11.56 | | |

| 10 | 58.3 | 1660 | 1017 | 17.23 | | |

| 11 | 58.7 | 1460 | 1019 | 16.02 | 0.724 | 2.27 |

| 12 | 58.5 | 1060 | 1022 | 11.82 | | |

| 13 | 59.4 | 1920 | 1014 | 16.59 | 0.689 | 2.53 |

| 14 | 59.4 | 1460 | 1022 | 13.14 | | |

| 15 | 58.9 | 1320 | 1021 | 13.38 | 0.493 | 1.53 |

| 16 | 58.9 | 1900 | 1015 | 17.10 | | |

| 17 | 59.0 | 1410 | 1019 | 14.55 | | |

| 18 | 59.5 | 1650 | 1017 | 15.25 | 0.647 | 1.92 |

| 19 | 59.1 | 1120 | 1022 | 13.37 | | |

| 20 | 58.2 | 1150 | 1020 |⎫ | | |

| 21 | 58.2 | 980 | 1021 |⎪ | | |

| 22 | 59.1 | 1320 | 1022 |⎬ 11.56 | 0.480 | 1.50 |

| 23 | 59.4 | 1320 | 1016 |⎪ daily | daily | daily |

| 24 | 58.6 | 1160 | 1022 |⎪ average | average | average |

| 25 | 59.2 | 1300 | 1013 |⎭ | | |

| 26 | 59.0 | 860 | 1024 |⎫ | | |

| 27 | 59.2 | 1240 | 1024 |⎪ | | |

| 28 | 59.4 | 1440 | 1014 |⎪ | | |

| 29 | 59.5 | 820 | 1022 |⎬ 9.20 | 0.474 | 1.35 |

| 30 | 59.4 | 1000 | 1017 |⎪ | | |

| 31 | 59.2 | 920 | |⎪ | | |

| Nov. 1 | 59.4 | 1120 | 1015 |⎭ | | |

| 2 | 58.7 | 840 | 1026 |⎫ | | |

| 3 | 59.1 | 1290 | 1018 |⎪ | | |

| 4 | 59.0 | 680 | 1025 |⎪ | | |

| 5 | 58.5 | 305 | 1027 |⎬ 9.07 | 0.474 | 1.48 |

| 6 | 58.4 | 700 | 1023 |⎪ | | |

| 7 | 58.7 | 780 | 1022 |⎪ | | |

| 8 | 58.5 | 1720 | 1011 |⎭ | | |

| 9 | 58.2 | 1320 | 1015 |⎫ | | |

| 10 | 58.9 | 920 | 1020 |⎪ | | |

| 11 | 59.3 | 1640 | 1014 |⎪ | | |

| 12 | 58.9 | 780 | 1024 |⎬ 8.33 | 0.422 | 1.38 |

| 13 | 59.0 | 940 | 1025 |⎪ | | |

| 14 | 59.0 | 1180 | 1016 |⎪ | | |

| 15 | 59.0 | 1900 | 1013 |⎭ | | |

| 16 | 58.8 | 1080 | 1022 |⎫ | | |

| 17 | 59.0 | 1080 | 1018 |⎪ | | |

| 18 | 58.4 | 1500 | 1017 |⎪ | | |

| 19 | 58.2 | 1260 | 1018 |⎬ 9.60 | 0.398 | 1.50 |

| 20 | 58.1 | 1220 | 1025 |⎪ | | |

| 21 | 58.7 | 1120 | 1022 |⎪ | | |

| 22 | 58.7 | 1100 | 1021 |⎭ | | |

| 23 | 58.6 | 1140 | 1017 |⎫ | | |

| 24 | 58.4 | 1360 | 1017 |⎪ | | |

| 25 | 58.3 | 1700 | 1010 |⎪ | | |

| 26 | 58.2 | 1120 | 1023 |⎬ 9.00 | 0.447 | 1.52 |

| 27 | 59.4 | 1620 | 1017 |⎪ | | |

| 28 | 58.0 | 700 | 1027 |⎪ | | |

| 29 | 58.7 | 1660 | 1025 |⎭ | | |

| 30 | 58.5 | 800 | 1025 |⎫ | | |

| Dec. 1 | 58.0 | 700 | 1020 |⎪ | | |

| 2 | 57.4 | 680 | 1028 |⎪ | | |

| 3 | 57.0 | 640 | 1028 |⎬ 11.41 | 0.417 | 2.12 |

| 4 | 57.0 | 940 | 1032 |⎪ | | |

| 5 | 56.2 | 660 | 1032 |⎪ | | |

| 6 | 56.0 | 800 | 1029 |⎭ | | |

| 7 | 56.0 | 800 | 1026 |⎫ | | |

| 8 | 56.1 | 780 | 1030 |⎪ | | |

| 9 | 57.0 | 820 | 1022 |⎪ | | |

| 10 | 58.0 | 500 | 1025 |⎬ 8.91 | 0.412 | 1.43 |

| 11 | 57.1 | 580 | 1029 |⎪ | | |

| 12 | 57.3 | 820 | 1031 |⎪ | | |

| 13 | 57.8 | 580 | 1027 |⎭ | | |

| 14 | 57.5 | 740 | 1027 |⎫ | | |

| 15 | 57.5 | 1680 | 1015 |⎪ | | |

| 16 | 57.9 | 900 | 1021 |⎪ | | |

| 17 | 57.4 | 780 | 1013 |⎬ 7.96 | 0.413 | 1.50 |

| 18 | 56.9 | 800 | 1026 |⎪ | | |

| 19 | 57.4 | 730 | 1025 |⎪ | | |

| 20 | 57.4 | 800 | 1023 |⎭ | | |

| 21 | 57.4 | 1310 | 1017 |⎫ | | |

| 22 | 57.0 | 1370 | 1014 |⎪ | | |

| 23 | 57.0 | 980 | 1020 |⎪ | | |

| 24 | 57.0 | 865 | 1016 |⎬ 7.35 | 0.319 | |

| 25 | 57.4 | 1300 | 1017 |⎪ | | |

| 26 | 58.0 | 1390 | 1017 |⎪ | | |

| 27 | 57.3 | 1340 | 1018 |⎭ | | |

| 28 | 57.6 | 875 | 1019 |⎫ | | |

| 29 | 57.0 | 680 | 1020 |⎪ | | |

| 30 | 56.8 | 685 | 1029 |⎪ | | |

| 31 | 56.7 | 815 | 1026 |⎪ | | |

| 1904 | | | |⎬ 6.83 | 0.413 | 0.99 |

| Jan. 1 | 57.4 | 1150 | 1015 |⎪ | | |

| 2 | 57.9 | 1610 | 1023 |⎪ | | |

| 3 | 58.6 | 1120 | 1023 |⎭ | | |

| 4 | 58.3 | 1350 | 1011 |⎫ | | |

| 5 | 57.8 | 1255 | 1017 |⎪ | | |

| 6 | 58.0 | 925 | 1022 |⎪ | | |

| 7 | 58.6 | 1120 | 1016 |⎬ 7.04 | 0.372 | 0.95 |

| 8 | 58.4 | 1350 | 1020 |⎪ | | |

| 9 | 57.7 | 890 | 1026 |⎪ | | |

| 10 | 58.6 | 1510 | 1012 |⎭ | | |

| 11 | 57.9 | | | | | |

| 12 | 57.2 | 835 | 1017 | 8.32 | 0.408 | |

+-----------+-------+-------+------+-----------+-----------+-----------+

|Daily average from | | | | | |

| Oct. 26 | 1045 | 1021 | 8.61 | 0.414 | 1.42 |

+-------------------+-------+------+-----------+-----------+-----------+

Any elaborate discussion of the individual results, tabulated in the

foregoing tables, seems hardly necessary. To any one interested in the

details of the work, a study of the tables themselves will give the

necessary information. It may be well, however, to emphasize at once a

few of the fundamental points most striking in character which bear upon

the main problem. Take, for instance, the case of Oakman, where the data

are recorded for every day from October 4, 1903, to April 4, 1904. The

degree of proteid metabolism, as indicated by the excretion of nitrogen

through the kidneys, is here shown for each day of the six months. Up

to November 3, practically for a month, there was not observable any

very noticeable change in the rate of proteid metabolism, but commencing

with November 4, the nitrogen excretion dropped very rapidly, and as one

glances through the daily records for month after month, it is seen that

the daily nitrogen output through the kidneys fell to 6 to 8 grams per

day, with a daily average excretion of 7.42 grams of nitrogen, as figured

from October 21 to April 4.

Further, it will be noted that while the body-weight gradually declined

during the first three months, falling from 66.7 kilos down to 62.3 kilos

on January 18, from that date on to the close of the experiment the

body-weight was practically constant. Here, then, we see, under the use

of a prescribed diet quite sufficient in amount to satisfy the cravings

of the appetite, a lowering of proteid metabolism equal to that obtained

by the individuals of the preceding group. Again, if the body-weight of

Oakman is placed at 64 kilos, as representing the average between the

initial body-weight and the weight during the last three months, it will

be found that the output of metabolized nitrogen per kilo of body-weight

amounted to 0.116 gram; not widely different from similar data obtained

with men of the preceding group.

[Illustration: FRITZ

_Photograph taken at the close of the experiment._]

Moreover, these results obtained with Oakman are practically duplicated

by every other member of this group of soldiers detailed from the United

States Army. No exception whatever is to be seen, but every man shows

the same lowered proteid metabolism, with practical maintenance of

body-weight, with complete satisfying of the appetite, and without loss

of health, strength, or vigor, as will be enlarged upon later.

While in the case of Oakman, the nitrogen excreted was determined by an

analysis made each day, in the case of the other men of this group the

data are given mainly for weekly periods; the results being expressed,

however, in the average daily amount for each seven days’ period. By

comparing the figures for the daily excretion of nitrogen with the daily

dietary, it is easy to trace out the influence of the changes in diet on

the extent of nitrogen metabolism.

In considering the changes in the rate of proteid metabolism shown by all

the members of this group, it will suffice for present purposes to deal

mainly with the average results.

Compare now the average daily output of nitrogen through the urine from

November 1 until April 4—a period of five months—of each of these men.

Physiological economy in nutrition, with special reference to the minimal proteid requirement of the healthy man an experimental study · 第 114 / 237 题