II. Wheat receives some damage in winter.

Oats in May, when in the grass state, soon receive damage.

Barley, mangel, common turnips, rhubarb.

III. Laurels (British and Portugal), aucubas, yews, holly, gorse--receive

damage in winter, but more in summer.

Old grass meadows and pastures receive much damage in winter.

IV. Ashes, oaks, hazels, horse-chestnuts, walnuts, Spanish chestnuts, sloe

thorn.

V. Swedish turnip and cabbages, damson, other fruit trees, beech, elm,

birch, alder, sycamores.

=ACIDULÆ.= [L. pl.] In _medicine_, mineral waters rich in carbonic acid.

=ACIDULATED=. _Syn_. ACIDULATUS, L.; ACIDULÉ, Fr. Blended or flavoured

with an acid; made slightly sour. See KALI (Acidulated), DROPS, LOZENGES,

&c. In _chemistry_, the addition of an acid to a neutral or alkaline

liquid until it reddens blue litmus paper.

=ACIDUM.= [L.] An acid.

=ACNE.= [_Syn._ PIMPLED FACE.] There are two forms of this affection. 1st.

In young persons of both sexes; generally in phlegmatic habits. The

disease shows itself by hard pimples, with a small black spot on the apex,

unaccompanied with redness or inflammation at first, but after a while

they become red and inflamed, and sometimes suppurate, with a greasy look

of the skin between them. In this form of acne the black spots should be

picked out with a needle or a small pair of tweezers. A long piece of

thick matter, like a worm, is extracted; but is no worm. Afterwards wash

the face with water in which a small piece of Quillar bark has been

steeped, or with bitter almond emulsion, or borax, one drachm, water 4 oz.

When there is no inflammation, use Eau de Cologne, or a few drops of oil

of rosemary dissolved in spirit of wine, taking a small dose of magnesia

in the morning, or milk of sulphur daily. When the pimples are very

sluggish the cautious application of tincture of iodine, or of ointment of

nitrate of mercury, will be found serviceable.

2nd. Arises from intemperance. In this case a gradual change of habits is

essential. The use of soap should be avoided, and recourse had to warm

fomentations of slippery elm, or thin oat gruel. The following should be

applied to the pimples:--Cold cream, 1 oz., Goulard's extract 20 drops,

mixed together; or lemon juice diluted, or solution of borax in water. The

internal administration of the mineral acids combined with bitter tonics,

or small doses of iodide of potassium, will be found effectual.

_Treatment._ Fomentations, poultices, chloride of zinc solution

externally; sulphur and alteratives internally.

=ACOLOGY=. _Syn._ In _medicine_, the doctrine of, or a discourse on,

remedies or the materia medica.

=ACONITE.= (-nite). _Syn._ ACON'ITUM, L.; ACONIT, Fr.: AKONITUM, EISENHUT,

STURMHUT, Ger. Monkshood; wolfsbane. In _botany_, a genus of exogenous

plants. _Nat. ord._, Ranunculaceæ; _Sex. syst._, Polyandria Trigynia. They

are characterised by showy purple or yellow helmet-shaped flowers growing

in panicles, deeply cut leaves, and perennial (usually) tap-shaped or

tapering roots. The whole plant is highly poisonous, the roots being more

poisonous than the leaves. In _medicine_ and _materia medica_, the plant

Aconitum Napellus (which _see_).

_Symptoms._ Numbness and tingling in the mouth and throat, which are

parched; followed by giddiness, dimness of sight, and (sometimes)

delirium, but seldom complete coma; there is numbness and tingling of the

limbs, a loss of power in the legs, (in some cases) frothing at the mouth,

severe abdominal pains, nausea, vomiting, and diarrh[oe]a; tremors or

twitchings of the voluntary muscles, (sometimes) convulsions (in animals,

but not in man); sharp cries; pupil (generally) dilated, very rarely

contracted; pulse fitful and sinking; skin cold and livid; difficulty of

breathing; general prostration; loss of sensation or feeling,

insensibility, general trembling, fainting, and sudden death. The eyes are

often glaring; and, in some cases, the patient is completely paralysed,

yet retains consciousness to the last. The case generally proves fatal in

from 1 to 8 hours. If it last beyond this period there is hope of

recovery. (Fleming.)

_Antidotes._ Ammonia, or brandy, with artificial respiration if necessary:

cold affusion and friction, with warm towels to the back and limbs. See

ALKALOIDS.

=ACONITE LEAVES= (B. Ph.). _Syn._ ACONITI FOLIA, L. The fresh leaves and

flowering tops of _aconitum napellus_, Linn., gathered when about one

third of the flowers are expanded, from plants cultivated in Britain.

_Char._ Leaves smooth, palmate, divided into five deeply cut wedge-shaped

segments; excizing slowly, when chewed, a sensation of tingling. Flowers

numerous, irregular, deep blue, in dense racemes.

_Prep._ Extractum aconiti.

=ACONITE ROOT.= (B. Ph.). _Syn._ ACONITI RADIX, L. The dried root of

_aconitum napellus_. Imported from Germany, or cultivated in Britain, and

collected in the winter or early spring before the leaves have appeared.

_Prep._ Aconitia, the active principle; Linimentum Aconiti, 1 ounce to 1

fluid ounce; Tinctura Aconiti, 54-1/2 grains to 1 fluid ounce.

_Char._ Usually from one to three inches long, not thicker than the finger

at the crown, tapering, blackish-brown, internally whitish. A _minute_

portion, cautiously chewed, causes prolonged tingling and numbness.

=ACONITI FOLIA.= See ACONITE LEAVES.

=ACONITI RADIX.= See ACONITE ROOT.

=ACONITIA.= C_{30}H_{47}O_{7}N. (B. P.) _Syn._ ACONITIA, L. An alkaloid

obtained from aconite.

Take of

Aconite root, in coarse powder, 14 pounds.

Rectified spirit }

Distilled water } of each

Solution or ammonia } a sufficiency.

Pure ether }

Diluted sulphuric acid}

Pour upon the aconite root three gallons of the spirit, mix them well, and

heat until ebullition commences; then cool and macerate for four days.

Transfer the whole to a displacement apparatus, and percolate, adding more

spirit, when requisite, until the root is exhausted. Distil off the

greater part of the spirit from the tincture, and evaporate the remainder

over a water bath until the whole of the alcohol has been dissipated. Mix

the residual extract thoroughly with twice its weight of boiling distilled

water, and when it has cooled to the temperature of the atmosphere, filter

through paper. To the filtered liquid add solution of ammonia in slight

excess, and heat them gently over a water bath. Separate the precipitate

on a filter, and dry it. Reduce this to coarse powder, and macerate it in

successive portions of the pure ether with frequent agitation. Decant the

several products, mix and distil off the ether until the extract is dry.

Dissolve the dry extract in warm distilled water acidulated with the

sulphuric acid; and, when the solution is cold, precipitate it by the

cautious addition of solution of ammonia diluted with four times its bulk

of distilled water. Wash the precipitate on a filter with a small quantity

of cold distilled water, and dry it by slight pressure between folds of

filtering paper.

_Characters and Tests._ A white, usually amorphous, solid, soluble in 150

parts of cold, and 50 of hot water, and much more soluble in alcohol and

in ether; strongly alkaline to reddened litmus, neutralising acids, and

precipitated from them by the caustic alkalies, but not by carbonate of

ammonia or the bicarbonates of soda or potash. It melts with heat, and

burns with a smoky flame, leaving no residue when burned with free access

of air. When rubbed on the skin it causes a tingling sensation, followed

by prolonged numbness. It is a very active poison.

=ACONITIA, CRYSTALLISED.= C_{27}H_{40}NO_{10}. Exhaust the root of wild

aconite, carefully picked and powdered, with very strong alcohol, to which

1 per cent. of tartaric acid has been added. Distil at a gentle heat, and

sheltered from the air, to recover the alcohol. Treat the extract with

water to separate all the fatty and resinous matters. The solution which

contains the aconite in the state of acid tartrate is first shaken with

ether to remove colouring matters, and then the alkaloid is set free by

the addition of alkaline bicarbonate, until the cessation of

effervescence. A fresh treatment with ether of this alkaline solution

removes the alkaloid, which crystallizes upon the concentration of the

ethereal liquid, with an addition of petroleum spirit. The crystals are

colourless tables, rhombic or hexagonal, according to the modifications

produced principally in the acute angles. Crystallized aconitia is soluble

in alcohol, ether, benzine, and chloroform; insoluble in petroleum oils

and glycerine.

ACONITIA NITRATE, CRYSTALLISED. Crystallised aconitine q. s.; nitric acid,

sp. gr. 1·442, q. s. Saturate the nitric acid with the aconitine and

evaporate. Voluminous crystals are easily obtained (from 'Formulæ for New

Medicaments adopted by the Paris Pharmaceutical Society').--'Pharm.

Journal.' Owing to the decomposition which this alkaloid undergoes in the

animal organism, as well as to its liability to decompose during the

process of evaporation, and exposure to the air, it often becomes

extremely difficult, if not impossible, to obtain it in a separate state

in conducting a _post-mortem_ examination. The physiological effects seem

to furnish the most prominent and characteristic evidence of its presence

in such cases, or at any rate these may serve as a valuable guide to the

toxicologist.

Uncrystallised aconitia is sometimes contaminated with delphinia, as well

as with aconella, another constituent of aconite root. For the dissection

of these see ALKALOIDS. One fiftieth of a grain of aconitia is stated to

have killed a dog.

_Antidotes._ See ACONITE.

=ACONITIC ACID.= (Identical with _Pyrocitric Acid_.) An acid extracted by

Peschier from _aconitum napellus_, and by Bracconnot from _equisetum

fluviatile_. It exists in these plants chiefly in the form of aconitate of

calcium.

_Properties._ A white, colourless, semi-crystalline mass.

=ACONITINA.= See ACONITIA.

=ACONITINE.= See ACONITIA.

=ACONI'TUM.= [L.] Aconite. The pharmacop[oe]ial name of _aconitum

napellus_(see _below_).

=Aconitum Ferox.= (Ind. P.) _Habitat_. Temperate and sub-Alpine Himalaya,

at 10,000 to 14,000 feet elevation, from Gurhwal to Sikkim.

_Officinal part._ The dried root (_Aconiti ferocis Radix_), in common with

those of other Himalayan species, viz., _aconitum napellus_, _a.

palmatum_, and _a. luridum_, constitutes the drug well known in the

bazaars of Upper India under the Hindostani name of _Bish_ or _Bikh_.

It occurs in the form of tuberous roots of a more or less conical form,

from two to three inches in length, and from half an inch to one inch in

thickness at their upper end. They have usually a shrunken appearance, and

are covered with a dark shrivelled bark; fracture shining and resinous;

sometimes waxy, varying in colour from pale to deep brown. Some specimens

are white and spongy; and these, it is asserted, are superior in activity

to the more compact kinds. Inodorous; taste at first slightly bitter,

leaving a peculiar sense of numbness on the tongue and fauces. Active

principle, aconitia.

_Medical Properties and Uses._ Similar to those of _aconitum napellus_ of

Europe. _Preparations._ This root may be advantageously used for the

manufacture of aconitia, the proportion of this alkaloid being much larger

than in the European drug; and also for the preparation of Linimentum

Aconiti. From its greater activity, however, it is unsuited for the

preparation of this tincture, which is intended for external use.

=Aconitum Hetorophyllum.= (Ind. P.) _Habitat_. Western temperate Himalaya,

at 8000 to 13,000 feet elevation; from Indus to Kumaon. _Officinal part._

The dried root (_Aconiti heterophylli Radix_). Ovoid tuberous roots,

tapering downwards to a point, from one to one and a half inches or more

in length, and from three eighths to half an inch in thickness. The

surface, which is covered with a thin greyish epidermis, is slightly

wrinkled longitudinally, and marked here and there with root scars. It is

inodorous, and of a bitter taste, devoid of acridity. Does not contain

aconitia. It may be readily distinguished from other roots sold in the

bazaars under the same vernacular name (Atis) by its characteristic

bitterness. _Properties._ Tonic and antiperiodic. It may be administered

internally with safety, as it contains no poisonous principle.

_Therapeutic uses_. In convalescence after debilitating diseases, and in

intermittent and other paroxysmal fevers, it has been found an efficient

remedy. _Doses._ Tonic, 5 to 10 grains thrice daily; antiperiodic, 20 to

30 grains of the powdered root every three or four hours, irrespective of

the presence of pyrexia.

=Aconitum Napell'us.= [Linn.] _Syn._ ACONI'TUM, Ph. L., E., & D.;

ACONITNAPÈL, CHAPERON DE MOINE, Fr.; EISENHUT, BLAUERSTURMHUT, Ger. Early

blue wolfsbane, or deadly aconite. _Hab._ Various parts of Europe; grows

wild in England, flowering in June and July. The fresh and dried leaves

(ACONITI FO''LIUM), Ph. L. & E. The root (ACONITI RA'DIX), Ph. L. & D.

This is the species of aconite ordered in the pharmacop[oe]ias, and

commonly used in medicine. When chewed it imparts a sensation of acrimony,

followed by a pungent heat of the lips, gums, palate, and fauces, which is

succeeded by a general tremor and chilliness. The juice applied to a wound

or the unsound skin affects the whole nervous system. Even by remaining

long in the hand, or on the bosom, it produces unpleasant symptoms. Fatal

cases of poisoning, by eating the root in mistake for horseradish, have

been common of late years. The two roots may be, however, easily

distinguished from one another; when scraped aconite emits an earthy, and

horseradish its well-known pungent odour. Moreover, the shape of the roots

is very different. In the accompanying figure _a_ represents aconite root,

and _b_ horseradish root.

[Illustration]

The leaves should be gathered as soon as the flowers appear. The root

should be taken up in autumn. When the whole plant is employed, it should

be gathered as soon as the flowers begin to open. The strength (richness

in aconitia) varies considerably with the time of the year. 1 oz. of the

fresh root contains 1/4 to 3/4 gr. of aconitia; 1 lb. of the dried English

root contains from 12 to 36 gr. (Herapath). The leaves possess the

greatest activity just before flowering; the root, after it. The root is

at all times fully six times as strong as the leaves or herb. The wild

plant contains much more aconitia than that which is cultivated. The herb,

and all its preparations, lose their efficacy if long kept. The powder,

more particularly, cannot be relied on. Mr Holmes says it is difficult to

find in a commercial sample of aconite root one root in a dozen, which

upon fracture appears sound and in good condition.

_Properties, Antidotes, &c._ See ACONITE.

_Tests, &c._ See ACONITE.

_Uses, &c._ In small doses aconite is narcotic, powerfully diaphoretic,

and sometimes diuretic; in larger ones, the symptoms are similar to those

produced by aconitia. It acts as a powerful sedative on the heart's

action, and destroys sensibility without disturbing the mental faculties.

It has been given in chronic rheumatism, gout, paralysis, scirrhus,

scrofula, cancers, venereal nodes, epilepsy, amaurosis, intermittents,

&c.; but its exhibition requires the greatest possible caution. As a

topical benumber it has been used with great advantage in painful

affections depending on increased sensibility of the nerves. Externally it

"is most valuable for the cure of neuralgic and rheumatic pains. In

neuralgia, no remedy, I believe, will be found equal to it. One

application of the tincture produces some amelioration; and after a few

times' use, it frequently happens that the patient is cured. In some

cases, the benefit appears almost magical. In others, however, it entirely

fails to give permanent relief." "I do not think that in any (case) it

proves injurious." "When it succeeds, it gives more or less relief at the

first application. When the disease depends on inflammation, aconite will

be found, I think, an unavailing remedy." "In rheumatic pains,

unaccompanied with local swelling or redness, aconite is frequently of

very great service." (Pereira, iii, 691.) _Dose_, of the powder, 1 to 2

gr., gradually increased to 6 or 8. Dr Stocrk was the first who gave

wolfsbane internally, about the year 1762. It has since been successfully

employed in Germany in cases of chronic rheumatism, gout, &c., some of

which were of long standing and had resisted every other remedy. In

England it has been less extensively used.

=Aconitum Panicula'tum.= Panicled wolfsbane; a species formerly ordered in

the Ph. L.; and, with _a. napellus_, also in the Ph. U. S. It is less

active than the officinal species.

=A'CORN.= _Syn._ GLANS. QUER'CUS, L. The seed or fruit of the oak. In the

early ages of the world, acorns probably formed one of the principal

articles of the food of man. (Ovid, _Met._, i, 106; Virgil, _Georg._, i,

8; &c.) In modern times, during periods of scarcity, they have been

consumed as food on the Continent. Besides starch, they contain a peculiar

species of sugar, which crystallises in prisms, and is unfermentable; they

also contain tannic and gallic acids. Mannite and dulcose are the

substances which it most nearly resembles. (M. Dessaignes.) During the

autumn, acorns are said to be sometimes poisonous to cattle and sheep.

Supposed cases of so-called acorn poisoning are best treated by

withdrawing the supply of acorns, or removing the animals from the

pastures on which the acorns fall, and by the administration of aperients,

alkalies, and stimulants.

=AC'ORUS CAL'AMUS.= See SWEET FLAG.

=ACOTYLE'DONS= (-ko-te-l[=e]'-). _Syn._ ACOTYLE'DONES (d[)o]n-[=e]z; L.,

prim. Gr.), Jussieu; ACOTYLÉDONS, Fr.; OHNE SAMENLAPPEN, Ger. In _botany_,

plants whose seeds are not furnished with distinct cotyledons or

seed-lobes. _Acotyledonous plants_ form one of the two great divisions of

the vegetable kingdom, according to the natural system. They are

remarkable by increasing chiefly in length, by additions to their end; and

not by addition to the outside, as in Exogens; nor to the inside, as in

Endogens. They are also termed ASEX'UAL and FLOWERLESS PLANTS, and answer

to the CRYPTOGAMIA of the Linnean system. See ACROGENS, CELLULARES,

THALLOGENS, &c.

=ACOUS'TICS= (-kow'-). The science of audition and sound; that branch of

physics which treats of their cause, nature, and phenomena. The doctrine

of the production and transmission of sound is termed DIACOUS'TICS; that

of reflected sound CATACOUS'TICS.

=Acoustics.= In _medicine_, remedies employed to relieve deafness. See

DEAFNESS and DROPS, ACOUSTIC.

=ACQUETTA.= [IT., _Little Water._] _Syn._ AQUA TOFFANA; A. TOFFANIA;

ACQUETTA DI NAPOLI DELLA TOFFANA, IT. A celebrated poison, prepared by an

Italian woman named Toffano, or Tophana, and in great request in Rome

about the middle of the 17th century. The composition of this poison has

been a matter of frequent controversy. Pope Alexander VII, in his

proclamation, described it as "aquafortis distilled into arsenic." This

would produce a concentrated solution of arsenic acid. The Emperor Charles

VI, who was governor of Naples during Toffano's trial, declared to his

physician, Garelli, that it was arsenic (arsenious acid) dissolved in

_aqua cymbalariá_. According to Gerarde this cymbalarià was an aquatic

species of pennywort, highly poisonous. The only objection to the latter

statement is the smallness of the dose, regard being had to the

comparative insolubility of arsenious acid; but if the woman Toffano

prepared two poisons, as is probable from history--one, a single dose of

which was fatal, and another, of which the dose required repetition, and

which was more gradual in its activity--the discrepancy will be at once

removed.

=AC'RID.= _Syn._ AC'ER, AC'RIS, L.; ACRE (âcre), Fr.; BEISSEND, SCHARF,

Ger. In _chemistry_ and _medicine_, sharp, pungent, acrimonious. Acrid

substances are such as excite a sensation of pungency and heat when

tasted, and which irritate and inflame the skin; as mustard, turpentine,

cantharides, &c.

=ACRIDITY.= _Syn._ ACRETÉ, Fr.; ACRITUDO, L. The quality of being acrid.

=AC'RIMONY.= _Syn._ ACRIMO'NIA, L.; ACRIMONIÉ, ACRETÉ, Fr.; SCHARFE, Ger.

In _medicine_ and _chemistry_, the quality or property of inflaming,

irritating, corroding, dissolving, or destroying other bodies.

=ACROGENS.= _Syn._ ACROGENÆ, L.; ACROGÈNES, Fr. In _botany_, acotyledonous

or cryptogamic plants, in which stems and leaves, or an organisation

approaching leaves, are distinguishable; which have stomates or breathing

spores on their surface, are propagated by spores, and increase by the

growth of the stem at the point only. Ferns and club-mosses are examples

of this class of plants.

=ACROLEIN.= _Syn._ ACRYLIC ALCOHOL. This substance occurs amongst the

products of decomposition when glycerine or any of its compounds is

subjected to ordinary distillation. It derives its name from its violently

irritant effect upon the mucous membranes of the eyes and respiratory

organs. It is best prepared by the process of Redtenbacher (see 'Leibig's

Ann.,' xlvii, 114), by distilling in a capacious retort, a mixture of

glycerine with phosphoric anhydride, or with hydric-potassic sulphate (the

acid sulphate or bisulphate of potash); the vapours must be condensed in a

properly cooled receiver, which is luted on to the retort and provided

with a tube opening into a chimney having a good draught. The distilled

liquid separates into two layers, the upper one consisting of acrolein,

and the lower one of an aqueous solution of the same substance mixed with

a quantity of acrylic acid. This distillate, after digestion with finely

powdered litharge, with the object of neutralising the acid, must be

rectified by the heat of a water bath: the acrolein so obtained must be

submitted to a second rectification from calcic chloride. All these

operations must be conducted in vessels filled with carbonic anhydride

(carbonic acid) because acrolein becomes rapidly oxidized when exposed to

the air.

Acrolein is a clear colourless liquid, lighter than water, boiling at

about 125° F. It has great refracting power and a burning taste; when pure

it is neutral to test paper.

=AC'ROSPIRE= (-spire). _Syn._ ACROSPI'RA, L.; PLUMULE, Fr.; BLATTKEIM,

Ger. The shoot or sprout of a seed, when it begins to grow; the part of a

germinating seed termed the plume, or plumula.

When the growth of a seed begins to be developed, the germ, from which the

stem originates, shoots forth under the form of a delicate curved fibre,

which, gradually bursting its covering, makes its appearance at the end of

the seed. The fibrils of the radicle first sprout forth from the tip of

the grain; a white elevation appears, that soon divides into three or more

radicles, which rapidly grow larger, and are succeeded by the plumula,

which peeps forth at the same point, in the form of a pale green leaflet,

which, twisting thence beneath the husk to the other end of the seed,

ultimately bursts its prison-house, and becomes a perfect leaf. See

GERMINATION and MALTING.

=ACTINIC RAYS.= See ACTINISM.

=ACTINISM.= _Syn._ ACTINIC RAYS; CHEMICAL RAYS. A term given to a supposed

principle accompanying the heat and light of the sunbeam. Actinic rays

chiefly exist beyond the violet extremity of the solar spectrum, and are

characterised by the power of exciting chemical change, _e.g._, the

decomposition of certain silver salts (in photography); the combination of

a mixture of chlorine and hydrogen, &c. The so-called vital functions of

animals and plants are also greatly influenced by the actinic or chemical

rays.

=ACTINOGRAPH.= An instrument for registering the intensity of the chemical

influence (_actinism_) of the sun's rays.

=ACT, TOWNS IMPROVEMENT CLAUSES, 1847= (10 & 11 Vict., c. 34), The

following provisions of this Act are incorporated in the Public Health

Act, 1875, and refer exclusively to urban districts:--

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