Some years ago I found among my old books a small manuscript marked

“James Oliver. This Book Begun Aug. 12, 1685.” It is a rough sort of

account-book, containing among other things prescriptions for patients,

and charges for the same, with counter-charges for the purchase of

medicines and other matters. Dr. Oliver practised in Cambridge, where

may be seen his tomb with inscriptions, and with sculptured figures that

look more like Diana of the Ephesians, as given in Calmet's Dictionary,

than like any angels admitted into good society here or elsewhere.

I do not find any particular record of what his patients suffered from,

but I have carefully copied out the remedies he mentions, and find

that they form a very respectable catalogue. Besides the usual simples,

elder, parsley, fennel, saffron, snake-root, wormwood, I find the Elixir

Proprietatis, with other elixire and cordials, as if he rather fancied

warming medicines; but he called in the aid of some of the more

energetic remedies, including iron, and probably mercury, as he bought

two pounds of it at one time.

The most interesting item is his bill against the estate of Samuel

Pason of Roxbury, for services during his last illness. He attended this

gentleman,--for such he must have been, by the amount of physic which he

took, and which his heirs paid for,--from June 4th, 1696, to September

3d of the same year, three months. I observe he charges for visits as

well as for medicines, which is not the case in most of his bills. He

opens the attack with a carminative appeal to the visceral conscience,

and follows it up with good hard-hitting remedies for dropsy,--as I

suppose the disease would have been called,--and finishes off with a

rallying dose of hartshorn and iron.

It is a source of honest pride to his descendant that his bill, which

was honestly paid, as it seems to have been honorably earned, amounted

to the handsome total of seven pounds and two shillings. Let me add that

he repeatedly prescribes plaster, one of which was very probably the

“Dr. Oliver” that soothed my infant griefs, and for which I blush to say

that my venerated ancestor received from Goodman Hancock the painfully

exiguous sum of no pounds, no shillings, and sixpence.

I have illustrated the practice of the first century, from the two

manuscripts I have examined, as giving an impartial idea of its

every-day methods. The Governor, Johannes Secundus, it is fair to

remember, was an amateur practitioner, while my ancestor was a professed

physician. Comparing their modes of treatment with the many scientific

follies still prevailing in the Old World, and still more with the

extraordinary theological superstitions of the community in which they

lived, we shall find reason, I think, to consider the art of healing

as in a comparatively creditable state during the first century of New

England.

In addition to the evidence as to methods of treatment furnished by the

manuscripts I have cited, I subjoin the following document, to which

my attention was called by Dr. Shurtleff, our present Mayor. This is a

letter of which the original is to be found in vol. lxix. page 10 of the

“Archives” preserved at the State House in Boston. It will be seen

that what the surgeon wanted consisted chiefly of opiates, stimulants,

cathartics, plasters, and materials for bandages. The complex and varied

formulae have given place to simpler and often more effective forms of

the same remedies; but the list and the manner in which it is made out

are proofs of the good sense and schooling of the surgeon, who, it may

be noted, was in such haste that he neglected all his stops. He might

well be in a hurry, as on the very day upon which he wrote, a great

body of Indians--supposed to be six or seven hundred--appeared before

Hatfield; and twenty-five resolute young men of Hadley, from which town

he wrote, crossed the river and drove them away.

HADLY May 30: 76

Mr RAWSON Sr

What we have recd by Tho: Houey the past month is not the chiefest of

our wants as you have love for poor wounded I pray let us not want for

these following medicines if you have not a speedy conveyance of them I

pray send on purpose they are those things mentioned in my former letter

but to prevent future mistakes I have wrote them att large wee have

great want with the greatest halt and speed let us be supplyed. Sr Yr

Sert WILL LOCHS.

(Endorsed)

Mr. Lockes Letter Recd from the Governor 13 Jane & acquainted ye Council

with it but could not obtaine any thing to be sent in answer thereto. 13

June 1676.

I have given some idea of the chief remedies used by our earlier

physicians, which were both Galenic and chemical; that is, vegetable and

mineral. They, of course, employed the usual perturbing medicines

which Montaigne says are the chief reliance of their craft. There were,

doubtless, individual practitioners who employed special remedies with

exceptional boldness and perhaps success. Mr. Eliot is spoken of, in

a letter of William Leete to Winthrop, Junior, as being under Mr.

Greenland's mercurial administrations. The latter was probably enough

one of these specialists.

There is another class of remedies which appears to have been employed

occasionally, but, on the whole, is so little prominent as to imply a

good deal of common sense among the medical practitioners, as compared

with the superstitions prevailing around them. I have said that I have

caught the good Governor, now and then, prescribing the electuary of

millipedes; but he is entirely excused by the almost incredible fact

that they were retained in the materia medica so late as when Rees's

Cyclopaedia was published, and we there find the directions formerly

given by the College of Edinburgh for their preparation. Once or twice

we have found him admitting still more objectionable articles into his

materia medica; in doing which, I am sorry to say that he could

plead grave and learned authority. But these instances are very rare

exceptions in a medical practice of many years, which is, on the whole,

very respectable, considering the time and circumstances.

Some remedies of questionable though not odious character appear

occasionally to have been employed by the early practitioners, but they

were such as still had the support of the medical profession. Governor

John Winthrop, the first, sends for East Indian bezoar, with other

commodities he is writing for. Governor Endicott sends him one he had of

Mr. Humfrey. I hope it was genuine, for they cheated infamously in

the matter of this concretion, which ought to come out of an animal's

stomach, but the real history of which resembles what is sometimes told

of modern sausages.

There is a famous law-case of James the First's time, in which a

goldsmith sold a hundred pounds' worth of what he called bezoar, which

was proved to be false, and the purchaser got a verdict against him.

Governor Endicott also sends Winthrop a unicorn's horn, which was the

property of a certain Mrs. Beggarly, who, in spite of her name, seems to

have been rich in medical knowledge and possessions. The famous Thomas

Bartholinus wrote a treatise on the virtues of this fabulous-sounding

remedy, which was published in 1641, and republished in 1678.

The “antimonial cup,” a drinking vessel made of that metal, which, like

our quassia-wood cups, might be filled and emptied in saecula saeculorum

without exhausting its virtues, is mentioned by Matthew Cradock, in a

letter to the elder Winthrop, but in a doubtful way, as it was thought,

he says, to have shortened the days of Sir Nathaniel Riche; and Winthrop

himself, as I think, refers to its use, calling it simply “the cup.” An

antimonial cup is included in the inventory of Samuel Seabury, who died

1680, and is valued at five shillings. There is a treatise entitled “The

Universall Remedy, or the Vertues of the Antimoniall Cup, By John Evans,

Minister and Preacher of God's Word, London, 1634,” in our own Society's

library.

One other special remedy deserves notice, because of native growth. I

do not know when Culver's root, Leptandra Virginica of our National

Pharmacopoeia, became noted, but Cotton Mather, writing in 1716 to

John Winthrop of New London, speaks of it as famous for the cure of

consumptions, and wishes to get some of it, through his mediation, for

Katharine, his eldest daughter. He gets it, and gives it to the

“poor damsel,” who is languishing, as he says, and who dies the next

month,--all the sooner, I have little doubt, for this uncertain and

violent drug, with which the meddlesome pedant tormented her in that

spirit of well-meant but restless quackery, which could touch nothing

without making mischief, not even a quotation, and yet proved at length

the means of bringing a great blessing to our community, as we shall see

by and by; so does Providence use our very vanities and infirmities for

its wise purposes.

Externally, I find the practitioners on whom I have chiefly relied

used the plasters of Paracelsus, of melilot, diachylon, and probably

diaphoenicon, all well known to the old pharmacopoeias, and some of them

to the modern ones,--to say nothing of “my yellow salve,” of Governor

John, the second, for the composition of which we must apply to his

respected descendant.

The authors I find quoted are Barbette's Surgery, Camerarius on Gout,

and Wecherus, of all whom notices may be found in the pages of Haller

and Vanderlinden; also, Reed's Surgery, and Nicholas Culpeper's

Practice of Physic and Anatomy, the last as belonging to Samuel Seabury,

chirurgeon, before mentioned. Nicholas Culpeper was a shrewd charlatan,

and as impudent a varlet as ever prescribed for a colic; but knew very

well what he was about, and badgers the College with great vigor. A copy

of Spigelius's famous Anatomy, in the Boston Athenaeum, has the names

of Increase and Samuel Mather written in it, and was doubtless early

overhauled by the youthful Cotton, who refers to the great anatomist's

singular death, among his curious stories in the “Magnalia,” and quotes

him among nearly a hundred authors whom he cites in his manuscript

“The Angel of Bethesda.” Dr. John Clark's “books and instruments,

with several chirurgery materials in the closet,” were valued in his

inventory at sixty pounds; Dr. Matthew Fuller, who died in 1678, left a

library valued at ten pounds; and a surgeon's chest and drugs valued at

sixteen pounds.'

Here we leave the first century and all attempts at any further detailed

accounts of medicine and its practitioners. It is necessary to show in a

brief glance what had been going on in Europe during the latter part of

that century, the first quarter of which had been made illustrious in

the history of medical science by the discovery of the circulation.

Charles Barbeyrac, a Protestant in his religion, was a practitioner

and teacher of medicine at Montpellier. His creed was in the way of

his obtaining office; but the young men followed his instructions with

enthusiasm. Religious and scientific freedom breed in and in, until it

becomes hard to tell the family of one from that of the other. Barbeyrac

threw overboard the old complex medical farragos of the pharmacopoeias,

as his church had disburdened itself of the popish ceremonies.

Among the students who followed his instructions were two Englishmen:

one of them, John Locke, afterwards author of an “Essay on the Human

Understanding,” three years younger than his teacher; the other, Thomas

Sydenham, five years older. Both returned to England. Locke, whose

medical knowledge is borne witness to by Sydenham, had the good

fortune to form a correct opinion on a disease from which the Earl of

Shaftesbury was suffering, which led to an operation that saved

his life. Less felicitous was his experience with a certain ancilla

culinaria virgo,--which I am afraid would in those days have

been translated kitchen-wench, instead of lady of the culinary

department,--who turned him off after she had got tired of him, and

called in another practitioner. [Locke and Sydenham, p. 124. By

John Brown, M. D. Edinburgh, 1866.] This helped, perhaps, to spoil a

promising doctor, and make an immortal metaphysician. At any rate, Locke

laid down the professional wig and cane, and took to other studies.

The name of Thomas Sydenham is as distinguished in the history of

medicine as that of John Locke in philosophy. As Barbeyrac was found in

opposition to the established religion, as Locke took the rational side

against orthodox Bishop Stillingfleet, so Sydenham went with Parliament

against Charles, and was never admitted a Fellow by the College of

Physicians, which, after he was dead, placed his bust in their hall by

the side of that of Harvey.

What Sydenham did for medicine was briefly this: he studied the course

of diseases carefully, and especially as affected by the particular

season; to patients with fever he gave air and cooling drinks, instead

of smothering and heating them, with the idea of sweating out their

disease; he ordered horseback exercise to consumptives; he, like his

teacher, used few and comparatively simple remedies; he did not give any

drug at all, if he thought none was needed, but let well enough alone.

He was a sensible man, in short, who applied his common sense to

diseases which he had studied with the best light of science that he

could obtain.

The influence of the reform he introduced must have been more or

less felt in this country, but not much before the beginning of the

eighteenth century, as his great work was not published until 1675, and

then in Latin. I very strongly suspect that there was not so much to

reform in the simple practice of the physicians of the new community, as

there was in that of the learned big-wigs of the “College,” who valued

their remedies too much in proportion to their complexity, and the

extravagant and fantastic ingredients which went to their making.

During the memorable century which bred and bore the Revolution, the

medical profession gave great names to our history. But John Brooks

belonged to the State, and Joseph Warren belongs to the country and

mankind, and to speak of them would lead me beyond my limited subject.

There would be little pleasure in dwelling on the name of Benjamin

Church; and as for the medical politicians, like Elisha Cooke in the

early part of the century, or Charles Jarvis, the bald eagle of Boston,

in its later years, whether their practice was heroic or not, their

patients were, for he is a bold man who trusts one that is making

speeches and coaxing voters, to meddle with the internal politics of his

corporeal republic.

One great event stands out in the medical history of this eighteenth

century; namely, the introduction of the practice of inoculation for

small-pox. Six epidemics of this complaint had visited Boston in the

course of a hundred years. Prayers had been asked in the churches for

more than a hundred sick in a single day, and this many times. About a

thousand persons had died in a twelvemonth, we are told, and, as we may

infer, chiefly from this cause.

In 1721, this disease, after a respite of nineteen years, again appeared

as an epidemic. In that year it was that Cotton Mather, browsing, as

was his wont, on all the printed fodder that came within reach of

his ever-grinding mandibles, came upon an account of inoculation as

practised in Turkey, contained in the “Philosophical Transactions.” He

spoke of it to several physicians, who paid little heed to his story;

for they knew his medical whims, and had probably been bored, as we say

now-a-days, many of them, with listening to his “Angel of Bethesda,” and

satiated with his speculations on the Nishmath Chajim.

The Reverend Mather,--I use a mode of expression he often employed when

speaking of his honored brethren,--the Reverend Mather was right this

time, and the irreverent doctors who laughed at him were wrong. One only

of their number disputes his claim to giving the first impulse to the

practice in Boston. This is what that person says: “The Small-Pox spread

in Boston, New England, 1721, and the Reverend Dr. Cotton Mather, having

had the use of these Communications from Dr. William Douglass (that is,

the writer of these words); surreptitiously, without the knowledge of

his Informer, that he might have the honour of a New fangled notion,

sets an Undaunted Operator to work, and in this Country about 290 were

inoculated.”

All this has not deprived Cotton Mather of the credit of suggesting, and

a bold and intelligent physician of the honor of carrying out, the new

practice. On the twenty-seventh day of June, 1721, Zabdiel Boylston

of Boston inoculated his only son for smallpox,--the first person ever

submitted to the operation in the New World. The story of the fierce

resistance to the introduction of the practice; of how Boylston was

mobbed, and Mather had a hand-grenade thrown in at his window; of

how William Douglass, the Scotchman, “always positive, and sometimes

accurate,” as was neatly said of him, at once depreciated the practice

and tried to get the credit of suggesting it, and how Lawrence Dalhonde,

the Frenchman, testified to its destructive consequences; of how Edmund

Massey, lecturer at St. Albans, preached against sinfully endeavoring to

alter the course of nature by presumptuous interposition, which he would

leave to the atheist and the scoffer, the heathen and unbeliever, while

in the face of his sermon, afterwards reprinted in Boston, many of our

New England clergy stood up boldly in defence of the practice,--all this

has been told so well and so often that I spare you its details. Set

this good hint of Cotton Mather against that letter of his to John

Richards, recommending the search after witch-marks, and the application

of the water-ordeal, which means throw your grandmother into the water,

if she has a mole on her arm;--if she swims, she is a witch and must be

hanged; if she sinks, the Lord have mercy on her soul!

Thus did America receive this great discovery, destined to save

thousands of lives, via Boston, from the hands of one of our own

Massachusetts physicians.

The year 1735 was rendered sadly memorable by the epidemic of the

terrible disease known as “throat distemper,” and regarded by many as

the same as our “diphtheria.” Dr. Holyoke thinks the more general use

of mercurials in inflammatory complaints dates from the time of their

employment in this disease, in which they were thought to have proved

specially useful.

At some time in the course of this century medical practice had settled

down on four remedies as its chief reliance. I must repeat an incident

which I have related in another of these Essays. When Dr. Holyoke,

nearly seventy years ago, received young Mr. James Jackson as his

student, he showed him the formidable array of bottles, jars, and

drawers around his office, and then named the four remedies referred to

as being of more importance than all the rest put together. These were

“Mercury, Antimony, Opium, and Peruvian Bark.” I doubt if either of

them remembered that, nearly seventy years before, in 1730, Dr.

William Douglass, the disputatious Scotchman, mentioned those same four

remedies, in the dedication of his quarrelsome essay on inoculation, as

the most important ones in the hands of the physicians of his time.

In the “Proceedings” of this Society for the year 1863 is a very

pleasant paper by the late Dr. Ephraim Eliot, giving an account of

the leading physicians of Boston during the last quarter of the last

century. The names of Lloyd, Gardiner, Welsh, Rand, Bulfinch, Danforth,

John Warren, Jeffries, are all famous in local history, and are

commemorated in our medical biographies. One of them, at least, appears

to have been more widely known, not only as one of the first aerial

voyagers, but as an explorer in the almost equally hazardous realm of

medical theory. Dr. John Jeffries, the first of that name, is considered

by Broussais as a leader of medical opinion in America, and so referred

to in his famous “Examen des Doctrines Medicales.”

Two great movements took place in this eighteenth century, the effect of

which has been chiefly felt in our own time; namely, the establishment

of the Massachusetts Medical Society, and the founding of the Medical

School of Harvard University.

The third century of our medical history began with the introduction of

the second great medical discovery of modern times,--of all time up to

that date, I may say,--once more via Boston, if we count the University

village as its suburb, and once more by one of our Massachusetts

physicians. In the month of July, 1800, Dr. Benjamin Waterhouse of

Cambridge submitted four of his own children to the new process of

vaccination,--the first persons vaccinated, as Dr. Zabdiel Boylston's

son had been the first person inoculated in the New World.

A little before the first half of this century was completed, in the

autumn of 1846, the great discovery went forth from the Massachusetts

General Hospital, which repaid the debt of America to the science of the

Old World, and gave immortality to the place of its origin in the memory

and the heart of mankind. The production of temporary insensibility at

will--tuto, cito, jucunde, safely, quickly, pleasantly--is one of those

triumphs over the infirmities of our mortal condition which change the

aspect of life ever afterwards. Rhetoric can add nothing to its glory;

gratitude, and the pride permitted to human weakness, that our Bethlehem

should have been chosen as the birthplace of this new embodiment of the

divine mercy, are all we can yet find room for.

The present century has seen the establishment of all those great

charitable institutions for the cure of diseases of the body and of the

mind, which our State and our city have a right to consider as among the

chief ornaments of their civilization.

The last century had very little to show, in our State, in the way of

medical literature. The worthies who took care of our grandfathers and

great-grandfathers, like the Revolutionary heroes, fought (with disease)

and bled (their patients) and died (in spite of their own remedies); but

their names, once familiar, are heard only at rare intervals. Honored

in their day, not unremembered by a few solitary students of the past,

their memories are going sweetly to sleep in the arms of the patient

old dry-nurse, whose “blackdrop” is the never-failing anodyne of

the restless generations of men. Except the lively controversy on

inoculation, and floating papers in journals, we have not much of value

for that long period, in the shape of medical records.

But while the trouble with the last century is to find authors to

mention, the trouble of this would be to name all that we find. Of

these, a very few claim unquestioned preeminence.

Nathan Smith, born in Rehoboth, Mass., a graduate of the Medical School

of our University, did a great work for the advancement of medicine and

surgery in New England, by his labors as teacher and author, greater,

it is claimed by some, than was ever done by any other man. The two

Warrens, of our time, each left a large and permanent record of a most

extended surgical practice. James Jackson not only educated a whole

generation by his lessons of wisdom, but bequeathed some of the most

valuable results of his experience to those who came after him, in a

series of letters singularly pleasant and kindly as well as instructive.

John Ware, keen and cautious, earnest and deliberate, wrote the two

remarkable essays which have identified his name, for all time, with

two important diseases, on which he has shed new light by his original

observations.

I must do violence to the modesty of the living by referring to the many

important contributions to medical science by Dr. Jacob Bigelow, and

especially to his discourse on “Self-limited Diseases,” an address which

can be read in a single hour, but the influence of which will be felt

for a century.

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