making new protein retains the power of growth, so that even though it
may be long past the ordinary age of maturity it can go on growing as
soon as the necessary materials are provided. The dependence of growth
on certain dietary accessories was spoken of in Chapter IV and need not
be repeated here.
The final use of food is as a source of energy for carrying on
metabolism. A good deal was said about that in an earlier chapter, but
there are a few additional points to be brought out here. The energy for
metabolism can come from any of the foodstuffs; these are present in the
blood stream in the form of sugar or fat or amino acids. A moment ago we
saw that in the case of the amino acids the nitrogen is removed before
they are ready for use as fuel. After this has happened the part that
remains is so similar to sugar that it can be thought of as the same
material and will be so considered by us. We have then to follow only
the two food substances, sugar and fat, through their use by the body
cells. Fat will be dealt with first since we have less to say about it.
It passes from the digestive tract into the blood stream in the form
known as an _emulsion_; all this means is that it is broken up into very
tiny particles which are kept from running together by some sort of a
film. In the case of the fats in the blood it is likely that this film
is composed of ordinary soap. In this state the fat circulates in the
blood stream until it is taken out by the tissues and burned. In the
process of this burning some very poisonous substances are likely to be
produced, but this happens only when large amounts of fat are being
burned by themselves. If sugar is present and is being burned at the
same time, there is no danger. Ordinarily in the body sugar is always
present, but in a certain disease, diabetes, about which more will be
said later, the body is not able to burn sugar as well as it ordinarily
does, and under these circumstances poisoning from the products of the
fat burning is apt to happen. This makes up, in fact, the serious danger
in diabetes. As we all know, fat is chiefly important as the form in
which food is stored in the body against a time of future need. We shall
return to the way in which the body does this after we have spoken of
the use of sugar as fuel.
Sugar is the great fuel substance of the body. About two-thirds or our
food ordinarily consists of starchy materials which are digested into
sugar. When we add to this the sugarlike remains of all the protein food
which is not actually used for the repair of tissues we see that this
substance makes up the great bulk of the material which is carried by
the blood to the tissues. This material is handled in the body in an
interesting way which depends on the curious fact that although sugar is
the most important fuel for living cells they cannot endure its presence
in them or in the fluids surrounding them except in very small amounts.
Sugar, as we all know, is very soluble in water, and it would be
perfectly possible for the blood to dissolve all the sugar that enters
it from the digestive tract and simply carry it in solution until the
tissues withdrew it for their needs; but this would mean that
immediately after every meal the percentage of sugar in the blood would
mount up to a high point from which it would gradually sink as the sugar
was taken out, to mount again after the next meal when absorption began
again. This does not actually happen because it is prevented by the
liver, which has as the most important of its many functions that of
storing the sugar that is taken up by the blood from the digestive tract
and dealing it out little by little as the cells of the body need it.
Back in the chapter on digestion we saw that all the blood that passes
through the intestinal tract is gathered up by the portal vein and
passes through the capillaries of the liver. It is during this passage
through the liver that the sugar is taken out of the blood and stored in
the form of a less easily dissolved material known as animal starch or
_glycogen_. The liver cells have the ability to convert sugar into
glycogen and they do this whenever the amount of sugar in the blood
passing through them is greater than the very small amount which is
suitable for the body cells. The blood that leaves the liver carries in
it only this small percentage. The liver cells have the ability to
change glycogen back into sugar, and this they do whenever the blood
that enters them is deficient in it, so that the blood leaving the liver
tends always to have the same amount of sugar in it. Whenever it enters
with more, there is a conversion of sugar into glycogen; whenever it
enters with less, there is a conversion of glycogen back into sugar.
So important is the protection of the body cells against having too much
sugar in the fluids surrounding them that the kidney acts to prevent
undue accumulation; this it does by withdrawing from the blood and
passing out into the urine any sugar that may be in the blood in excess
of the small amount which the tissues are able to endure. Thus we see
that if the liver did not have its function of converting the sugar into
glycogen we would have to change our eating habits completely, taking
only a little food at a time instead of eating it in three meals, since
otherwise most of our food would be wasted by being passed out from the
kidneys as fast as it was poured into the blood from the digestive
organs. There is a limit to the ability of the liver to change sugar
into glycogen. If the amount in the portal vein at any one time goes
above a certain figure, not all will be saved: a part will escape into
the blood stream, and since this will raise the percentage, the kidney
comes into action and passes it out. In order for this to happen, there
must be a very large amount of digested sugar in the small intestine
leading to rapid absorption. Since some starchy foods are easier to
digest than others some diets are more likely to result in the
appearance of sugar in the urine than others. Some of our common foods,
notably honey and corn sirup, consist largely of the kind of sugar the
body uses. These require no digestion at all, but are ready for
absorption as soon as they enter the small intestine. Naturally, if they
are eaten in any quantity, they are likely to flood the liver with sugar
beyond the amount which it can change to glycogen. Common table sugar
and the sugar of milk have to be digested before they are absorbed and
so are less likely to flood the liver. It is true, however, that either
of them if taken in very large amounts may do this. The digestion of
starch goes on much more slowly and so is absorbed more gradually and it
is doubtful whether the liver is ever flooded on a starch diet. Since
the presence of sugar in the urine is a common indication of diabetes,
it is necessary to know that other conditions may bring it about.
Obviously, as in the case of an examination for life insurance, a
perfectly healthy person might be rejected on account of the presence
of sugar in his urine, if it were not that the examining physician knows
of this other possibility and is on his guard against it.
The liver ordinarily turns glycogen back into sugar at just the rate
necessary to keep the amount in the blood constant. This means that when
functional metabolism is going on glycogen is being turned into sugar
more rapidly than when the body is quiet. One of the very interesting
discoveries of recent years is that in times of strong excitement
leading to the outpouring of adrenalin into the blood the rate of change
of glycogen into sugar is much increased, so that instead of the usual
small amount there is present in the blood a large concentration of
sugar. This is evidently advantageous in insuring ample fuel supplies to
the muscles at the time of an emergency. It is wasteful in that a large
part of the surplus sugar is passed out by the kidneys. The fact is
illustrated that in marshaling the bodily functions for meeting an
emergency economy is lost sight of.
In addition to these healthy conditions in which sugar may appear in the
urine there is the disease diabetes, in which the presence of sugar in
the urine is a conspicuous symptom. In diabetes there is a serious
disturbance of the whole fuel-supplying mechanism; the liver does not
carry on its function of changing sugar to glycogen and glycogen back to
sugar as perfectly as it should, and what is of much more importance the
muscles which are the chief users of sugar as fuel cannot use sugar in
anything like their usual manner. In fact in severe cases they appear to
be almost wholly unable to use sugar as fuel. Since the protein from
which the nitrogen has been removed classes itself with sugar in this
regard, the muscles are thrown back upon fat as their only source of
fuel, and this confronts the body with the danger already mentioned that
in the burning of fat when little or no sugar is being burned along with
it very poisonous products may be formed. Medical investigators have
devoted a vast amount of labor to the attempts to find a diet that can
be successfully eaten by diabetics. Starches and, almost equally,
proteins are not serviceable because they simply flood the tissues with
sugar, making an environment which is not good for the cells, and
keeping the kidneys busy getting rid of the surplus. Fats are dangerous
for the reason just stated. Quite recently real progress has been made
by means of the discovery that when the body is living on its own tissue
there will be no accumulation of sugar in the body fluids nor outpouring
of it from the kidneys. One who is being starved is living on his own
tissues and so by simply starving a diabetic his symptoms can be
relieved. This is not in itself a very promising expedient, since
evidently without food one cannot go on living very long. The point of
the treatment is that after starvation has proceeded until the body is
actually living on its own tissue it is possible to begin feeding
proteins cautiously until little by little a protein diet can be
established in which there is little or no indication of surplus sugar.
In other words it seems that when the body is compelled to live upon its
own tissue it uses proteins efficiently and will then go on using them
efficiently when they are supplied to it in the diet.
In an earlier section of the chapter we talked about the amount of
protein that the body requires; now we have to take up the matter of the
amounts of energy-yielding foods. It is evident that the amounts of
these depend upon the amount of metabolism; the total metabolism is made
up of the basic metabolism which is steady, shifting little day in and
day out, plus the functional metabolism which depends upon how actively
the body works. The main functional metabolism is that of the muscles
and it is that which varies from day to day. In the case of children
there is the additional metabolism of growth for which energy is
required and for which food must be eaten. In order to talk
intelligently about the use of foods for metabolism we must have a word
by which to express a definite amount of it. The word that we use for
this is “calory.” Primarily this word stands for a certain amount of
energy in the form of heat; since one kind of energy can be transformed
into another kind without changing the actual energy value we can use
this word as a measure of all kinds of energy and this has become the
custom. The calory as a unit of energy means really the amount of energy
in the form of heat required to raise the temperature of 1,000 grams of
water by 1 degree centigrade. We can translate it into more familiar
terms by stating that it equals almost exactly the amount of energy
required to raise a weight of 300 pounds to a height of 10 feet, or 30
pounds to a height of 100 feet, or any other combination of weight in
pounds multiplied by distance in feet which figures up to 3,000.
The total metabolism, as we said a moment ago, varies greatly day by day
because the extent to which we use our muscles is so different. The
basic metabolism is very steady and the functional metabolism of the
vital processes like breathing, the heartbeat, etc., is also pretty
steady, so that the metabolism for one who makes no use of his muscles
is fairly uniform. Of course it differs in large people as compared with
small, although curiously enough the difference is not proportional to
the weight but to the body surface. Just why this is so we do not know.
The average figure for the total metabolism of a resting man is about
1,900 calories a day; this includes the motions that are necessary for
eating and swallowing food, since life cannot go on indefinitely without
making those motions, but supposes that all other activities are done
away with. This figure, as we said a moment ago, holds pretty steady day
in and day out. To find the total metabolism on any day we have simply
to add to it the figure for the energy expenditure from the use of the
muscles, which will vary with the amount of work that is done. In
figuring this we have to reckon with the fact that the muscles are like
other machines in working at what is called in engineering a low
efficiency; by that we mean that the amount of energy that can be gotten
out in the form of useful work is less than the energy that is actually
consumed; there is a waste of energy which takes the form of heat. Our
muscles are under ordinary circumstances about twenty per cent
efficient, which means that for every calory-worth of actual muscular
work we do we use up five calories-worth of fuel; the energy of four
wasted calories takes the form of heat and we all know from experience
that the amount of heat thus produced inside our bodies warms us up very
quickly, when we are using our muscles actively.
The actual muscular work done in a day by individuals varies from almost
nothing in the case of invalids confined to bed through about forty
calories for a person of decidedly sedentary habits and about 120
calories for the average clerical or professional man up to from 300 to
400 in the case of manual laborers. These figures are for the actual
muscular work done; to obtain the energy expenditure we have to multiply
each of them by five on account of the inefficiency of the muscles. If
we do this and then add to each product the constant figure of 1,900 for
the metabolism of rest we obtain for the total metabolism of a decidedly
sedentary person an average of about 2,100 calories; for an average
clerical or professional man 2,500 calories, for manual laborers from
3,200 to 4,000 calories. Of course, individuals may exceed even these
latter figures. It is believed that athletes in extreme competitions
such as for example a six-day bicycle race may liberate energy at the
rate of 10,000 calories a day, although they probably cannot keep this
up long enough actually to do that amount in a single day.
In order to satisfy the requirements of metabolism the food that is
eaten must yield corresponding amounts of energy. If it does not do so
enough of the tissues will be consumed to make up the deficiency. Of
these the first to be drawn upon will be the stored glycogen in the
liver and secondly the body fat. Only when the deficiency is great
enough so that all these are used up, does the protoplasm itself begin
to be drawn upon as a source of fuel. This happens in cases of prolonged
starvation and it is interesting to note that in this case the tissues
drawn upon are the muscles. When one wastes away as the result of
starvation, the only tissues that suffer serious loss at first are the
muscles; the rest of the body is fed at their expense. In this process
no muscle cells are actually destroyed--apparently each can sacrifice a
little of its protoplasm without being itself injured; the material thus
obtained is converted into amino acids and from most of these the
nitrogen is removed, leaving a fuel material which can be burned in the
cells all over the body to keep them going. It is only after extreme
starvation, when the muscles can no longer yield of their substance
without being themselves destroyed, that the other tissues begin to show
serious wastage. This explains why the brain of a starving man remains
clear almost up to the end.
If a surplus of food is eaten over the energy requirements, the liver
will store it in the form of glycogen so far as it is able; but if this
will not suffice, the excess will be changed into fat and stored in the
body in what are called adipose tissues. These are located in various
regions, one of the most important being directly under the skin. It is
the loading of this with fat that causes the bodily enlargement of fat
people. We do not know exactly how the fat is made; we do know that it
is not ordinarily food fat that has been simply transported to these
tissues and deposited there. There is abundant proof that the body can
manufacture fat even if there is none in the diet. Grazing cows that get
no fat of any kind produce milk with its regular percentage of fat in
the form of cream and do this day in and day out, showing that the fat
that the body makes does not have to come from fat in the food. Since
body fat represents ordinarily a storage of fuel against a future need,
we ordinarily think of it as made whenever the temporary storage in the
form of glycogen becomes inadequate to take care of the surplus of food
over the amount consumed in carrying on the metabolism. Since the vast
majority of people are neither gaining nor losing weight, the amount of
food that they take in each day must balance the average metabolism.
This is interesting because the amount of food that is eaten is
regulated chiefly by the sense of hunger, or by the hunger and appetite
together, and it is remarkable that these should cause us to eat so
accurately just the amount of food our metabolism requires. In order
that we may get some idea of how much energy is furnished in our common
foods a table is given below. The figures are for the numbers of
calories in a pound of the food material as purchased in the market. In
most vegetables and meats there is a loss of about ten per cent in
preparing them for the table, or, in the case of meat, in the bones. The
figures were prepared by officials of the United States Government in
arranging dietaries for the Army.
CALORIES PER POUND AS PURCHASED
Apples, fresh 219
Bacon 2,979
Bananas 298
Beans, dried 1,603
Beef, fresh 1,009
Bread 1,300
Butter 3,478
Cabbage 124
Celery 70
Cheese, American 1,948
Chocolate 2,858
Eggs 614
Fish, salmon, canned 679
Fish, fresh 368
Flour 1,651
Lard and substitutes 4,218
Milk 302
Pork, salt 2,948
Potatoes, white 311
Rice 1,631
Sugar 1,860
Tomatoes 106
Very few of our foodstuffs are exclusively of one kind of material; that
is they are not exclusively protein or exclusively fat or exclusively of
sugar or starch compounds. Most vegetables are mixtures of starch with
protein, fruits are mixtures of starch and sugar with a little protein,
both fruits and vegetables contain so much water that their actual fuel
value per pound amounts to little. Meats are mixtures of proteins with
fats. Milk is a mixture of proteins, sugar, and fat. Table sugar and
butter are as near pure unmixed foodstuffs as any of the things we
commonly eat. In an earlier part of the chapter we saw that about
two-thirds of our ordinary diet is of starch or starchlike materials.
This figure is given, not in weight of material, but in the energy
value. What it means is that about two-thirds of the energy for our
metabolism comes from the starch and sugar that we eat; the other
one-third is divided between fat and protein in the proportion of about
two to one. The energy we get from fat being about double that which we
get from protein--since a given weight of fat has about twice the energy
value of the same weight of protein--we actually eat about the same
amount of protein as of fat. The combined weight of the starch and sugar
is between four and five times that of the protein. These, of course,
are average figures representing not what we eat at any one meal, but
the way in which the foodstuffs are found to be divided in our diet
taken as a whole. Where meals have to be planned on a large scale, as in
armies or in institutions where the persons to eat the food have not
much choice in selecting them, it is necessary that the diets be
arranged both to give the proper amounts of material and also to furnish
them in about the correct proportions. The dietary experts who have
charge of these matters do this with tables similar to the one given
above. In domestic feeding arrangements, although usually the choice of
foods is determined by the state of the markets, the preferences of the
various members of the family, and the abilities of the cook, it is
astonishing how closely the result will correspond in the long run to
the figures here given. Most of us, without any effort on our part to do
so, eat a diet which is made up week in and week out in just about the
proportions here given. The experience of ourselves and of all our
ancestors indicates that these are the correct proportions for the human
race.
In talking about metabolism thus far we have spoken as though the
metabolism of the body at rest were about the same day in and day out
regardless of conditions. This is true in the main for healthy persons;
there is one condition which may bring about a change in the resting
metabolism of health which must be mentioned, and one or two coming
under the category of disease about which also something must be said.
The change in resting metabolism that comes about in health is one that
is seen when the diet contains an especially large percentage of
protein. For some reason which we do not understand the digestion,
absorption, and utilization of protein stimulate the resting metabolism
so that during the time that this protein is being used the metabolism
is higher than at other times. The curious thing about it is that the
increase of metabolism is not just enough to take care of the protein
itself, but goes so far to cause sugars or even fats to be burned at a
more rapid rate than usual. This fact is taken advantage of in treatment
for reducing flesh; where one lays on flesh it is evident that more food
has been taken than was required for metabolism so that the surplus has
been stored in the form of fat. The only way to reduce the weight is to
compel the body to burn up that stored fat. In theory the simplest way
to do this is simply to starve. If starvation is combined with very
vigorous exercise, the reduction of weight is bound to be rapid, since
metabolism cannot be carried on without fuel, and if not enough fuel is
supplied in the form of food, the body will have to furnish it and the
stored fat is the place from which it will be taken. Unfortunately this
is much simpler in theory than it is in practice. A good deal of
discomfort and sometimes even disturbance of health results from too
drastic efforts to reduce the weight by starvation. It is perfectly
feasible to do it by adopting and sticking to a practice of never eating
quite enough. This is a perfectly successful method, but requires great
strength of will to carry it out. Probably the easiest way to reduce
weight is to combine self-denial with a diet which consists chiefly of
protein. Thus the stimulating effect upon metabolism is obtained and the
result will be a gradual burning away of the body fat. The selection of
a diet to fit any particular individual can best be made under competent
medical advice, since personal peculiarities have to be taken into
account in selecting among the various foods those best adapted for the
purpose.
The variations in resting metabolism that fall under the head of disease
are, first, the increase of metabolism in fever, about which we shall
speak in detail in the next chapter, and, secondly, variations in
metabolism that result from variations in the activity of the thyroid
gland. The thyroid gland is an organ at the front of the neck; when it
is enlarged, as it is in some people, we have the condition known as
goiter. This gland is now known to manufacture and pour out into the
blood a hormone which is a regulator of metabolism. When it is produced
in normal amounts, the metabolism goes on at the rate that we find in
healthy people. If the gland is inactive and does not secrete enough of
the hormone, there is a reduction in the metabolism. Since this implies
a lowering of the vigor of the life processes, we might expect it to
have important effects. The most marked of these are in the nervous
system. Persons whose thyroid glands are relatively inactive are
mentally sluggish; the less active the gland is, the more marked is this
sluggishness, and in case of practically complete absence of the hormone
the condition amounts to idiocy. Occasionally a child is born without an
active thyroid gland; this child is doomed for life, unless artificial
aid can be procured, not only to complete idiocy but to all the other
results of lowered metabolism; these show themselves in dwarfishness and
a misshapen body. One of the conspicuous and beneficent discoveries of
medicine in comparatively recent years has been that extracts of the
thyroid glands of meat animals, when eaten by persons whose own thyroids
are not sufficiently active, supply the lack, and so they may be
restored to the normal condition. There are many people alive to-day who
are in all respects normal, but who, if they were to discontinue taking
thyroid extract, would relapse rapidly into a condition of idiocy.
The thyroid gland may sometimes become overactive as well as
underactive; when the former happens we have an increase in the resting
metabolism and a group of symptoms that indicate, so far as the nervous
system is concerned, a condition of overexcitability. Unfortunately
this does not mean exceptional mental power but rather mental
instability. The victims of this condition are exceptionally quick
nervously, but they are quick to take offense and quick to be disturbed
by all sorts of conditions. If the overactivity of the gland becomes too
pronounced, mental instability or even marked insanity results. Another
fact of the heightened metabolism is that large amounts of food must be
eaten to carry it on. Sufferers from overactivity of the thyroid gland
eat voraciously, but, in spite of doing so, are thin or even emaciated.
They have rapid heartbeat, high blood pressure, and other symptoms
indicative of too great activity of the gland. The successful treatment
of this condition depends on the removal by surgery of enough of the
thyroid gland to reduce the outpouring of the hormone to the normal
amount. This feat is now accomplished successfully by our most skillful
surgeons, and the result has been the restoring to health and happiness
of large numbers of people whose lives were rendered miserable through
no fault of their own, but because their thyroid glands had become
unduly active. We do not know how the thyroid gland itself is
controlled; there is evidently something which causes it in the vast
majority of us to produce its hormone at the rate which keeps the
metabolism steady at what we look upon as the level of health. Deficient
thyroid is, at least in some cases, hereditary. Excessive thyroid
activity seems to be rather the secondary result of some preceding
disturbance of the nervous system, but as to that we cannot say with
confidence.
CHAPTER XIX
KEEPING WARM IN WINTER AND COOL IN SUMMER
A good deal of what has been said thus far in the book applies to nearly
all kinds of animals about as well as it does to man. We have now to
take up a feature found only in two great groups of the animal
kingdom--birds, and the four-legged animals, to which are given the name
of mammals. This peculiarity is commonly called warm-bloodedness. What
we really mean when we say that an animal is warm-blooded is that the
temperature of its body runs about the same summer and winter, day in
and day out. An animal that we call cold-blooded, on the other hand,
cools down when in a cold place, but is warm when in a warm place. It
therefore has a very variable temperature as compared with the almost
constant temperature of warm-blooded animals. The maintaining of the
warm-blooded condition, which means really the maintaining of a constant
temperature, involves only one thing, namely that the amount of heat
lost from the body shall exactly balance the amount of heat produced in
it. If more heat is produced than is lost, the temperature must rise; if
more heat is lost than is produced, the temperature must fall. These are
simple facts of physics which apply as well to the body of an animal as
to any other source of heat.
All animals produce heat, because in all of them metabolism is going on,
which means that in all of them energy is being liberated, and it is one
of the fundamental laws of physics that whenever any energy is liberated
all of it which does not take some other definite form is certain to
appear as heat. The other possible forms that the energy liberation of
the body may take are chemical energy in the manufacture of various
materials and the energy of motion. Whenever either of these processes
takes place a large amount of heat is produced in connection; this
means, from the standpoint of mechanics, as we have already seen, that
the body is an inefficient machine; if it were perfectly efficient, the
energy that it liberates might all go into the form either of motion or
of the manufacture of materials, with none left over to appear as heat;
but since it is only 20 per cent efficient, four-fifths of all the
energy that is displayed actually takes the form of heat. While this is
a marked inefficiency from the mechanical standpoint, from the
standpoint of bodily well-being it is by no means a bad thing, since it
is this constant production of heat which makes possible in birds and
mammals the maintenance of a constant and rather high temperature. That
it is a great advantage to the body to be warm all of the time is clear
when we compare the possibilities of our lives with those of
cold-blooded animals, like insects or frogs. Whenever the weather cools
down they necessarily become inactive since, as we saw in the third
chapter, when protoplasm is cooled, its metabolism necessarily slows
down, and when the cooling reaches a certain point the protoplasm
becomes completely inactive. The temperature of 98½ degrees F., which
our bodies maintain, is a temperature which is very well suited for an
active metabolism; by keeping this temperature all the year around they
are able to show this metabolism all the time instead of only in summer,
as in the case of the cold-blooded animals.
As we said a moment ago, the maintaining of a constant temperature is
altogether a matter of making the loss of heat balance the production of
heat; the production of heat is altogether a matter of the metabolism;
practically the whole of the resting metabolism takes the form of heat,
since apparently the expenditure of energy in keeping the protoplasm
alive is extremely wasteful; nearly all the energy that is actually
liberated takes the form of heat, almost none of it being used in actual
manufacture of material. This is, as has already been said, a very
constant metabolism; the functional metabolism on the other hand is
extremely variable depending on how hard we use our muscles; the total
amount of heat produced from hour to hour is scarcely ever the same
except when we are asleep; this means that the loss of heat, which has
to balance the production of heat, must vary from hour to hour exactly
parallel with the latter. In birds and in all mammals, except man, the
adjustment of heat loss to heat production is almost wholly automatic;
the animal or bird does very little to control it. We do see, however, a
few examples of effort on the part of animals either to prevent heat
from being lost too rapidly or to favor its more rapid loss. Thus, on a
cold day, a cat or dog is apt to lie curled up or with its legs bunched
under it; on a very warm day, on the other hand, it will lie stretched
out as much as possible, and in the case of the dog, with the tongue
hanging out full length. Birds sometimes are seen with feathers ruffled
up apparently in an effort to keep warm. Both birds and mammals seek
sheltered places in which to sleep, where they will be as little exposed
as possible to cold winds or rains. In man the automatic adjustment of
heat loss to heat production is very imperfect, in fact, it would not
enable men to live naked except in the tropics. It is true that outside
the arctic regions men might go naked and still make the heat production
equal the heat loss during the waking hours by very vigorous exercise,
but during the hours of sleep the loss of heat would be certain to be
much more rapid than its production and so the body temperature would
fall in severe weather enough to cause death. Man maintains himself
outside the tropics, then, by using artificial aids for maintaining the
balance between heat production and heat loss; these are of three sorts;
first the use of clothing, second the use of shelter, and third the use
of artificial heat. It is really a very curious fact when one stops to
think of it that, although many animals enjoy artificial heat and gladly
bask in it when opportunity offers, no animal has ever discovered the
simple fact that throwing sticks on a fire will keep it going, and so no
animals, except man, have ever made any real use of artificial heat.
When we think that the progress of human civilization has been
accomplished wholly in parts of the earth where clothing, shelter, and
fire are necessary to human existence, we realize that these, instead of
being mere incidents to our life, lie really at the very basis of
advancement. Hairless man is evidently a tropical animal; if he had not
devised means of maintaining himself outside the tropics, there is no
reason to suppose that he would have behaved any differently than have
the savages that inhabit those regions at the present time.
Clothing, shelter, and fire all operate to prevent us from losing heat
too rapidly and so have their great value when the weather is cool; we
also can and do bring about an increased heat production in cold weather
partly by exercising more actively and partly by increasing the amount
of protein in the diet, and so bringing into play the stimulating effect
of that substance on metabolism. This latter is seen perhaps most
strikingly in the experience of the Eskimos; when one of them comes in
from a hunting trip in the depth of winter very much chilled, he
scarcely stops to warm himself at all, but with the greatest haste gulps
huge quantities of meat that are barely thawed out, not really cooked in
our sense of the word; in fact, frequently the meat that is eaten is so
cold that it makes the Eskimo chillier than before; as soon, however, as
digestion and absorption have commenced, so that the stimulation of
metabolism can begin, the rapid production of heat in the body warms it
up to the point where complete comfort is obtained.
We have no other means of increasing heat production in our bodies
except by muscular exercise or eating protein. It is interesting to
note, however, that there is a form of involuntary muscular exercise
which comes into play when we need to produce more heat in order to
balance too rapid loss; this involuntary muscular action is the familiar
shivering which one does when chilly. It is reflex in the strict sense,
that is to say, the stimulation of cold on the skin arouses nervous
disturbances which pass to the muscles in various parts of the body and
set them into the violent movements which we call shivering. The
functional metabolism of shivering is much greater than we might at
first suppose, and the production of heat is correspondingly rapid. In
fact, if one who feels inclined to shiver encourages it instead of
attempting to keep from doing it, he will very quickly produce enough
heat within his body so that he will no longer have a disposition to
shiver.
We have seen above the various ways in which heat is produced in the
body, and the artificial means we employ to prevent heat from being lost
too rapidly. It is clear that all of these make up what we may call
coarse adjustments. They tend on the whole to cause heat to be produced
more rapidly when more is needed, or to prevent too rapid loss when
conditions are of a sort to bring it about. Nothing that has yet been
said accounts for the fine adjustment, that is, for the actual
maintaining from moment to moment of a balance of the heat loss with the
heat production. This fine adjustment is purely automatic and is carried
on in us by two distinct means. The first of these is by an automatic
regulation of the amount of blood flowing through the skin and so,
within certain limits, of the temperature of the skin. It is evident
that if the skin is warm heat will be given off from it more rapidly
than if it is cool; a condition in which the balance is being upset by
the failure of the body to lose heat rapidly enough can be corrected, at
least in part, by causing the skin to become warmer and so more heat to
be given off. The machinery for regulating the amount of blood flowing
through the skin is the vasomotor system, about which a good deal has
already been said. This system operates reflexly, stimulation of cold on
the skin tends to diminish the flow of blood through it by contracting
the blood vessels, while warmth on the skin has just the opposite
effect, causing the blood vessels to become flushed and the blood flow
to be more rapid. It is true that there is a reddening of exposed parts
of the skin in extreme cold, as we all see frequently on our nose or
ears, but this is a purely local effect and does not mean that the blood
is flowing through the region rapidly enough to keep up its temperature
and so favor the loss of heat. These changes in the amount of blood in
the skin are very effective in the fine regulation of heat loss. The
body can get rid of heat very much more effectively when the skin is
flushed than when it is pale. There are, however, limits to the
usefulness of this arrangement. Even when the skin is as pale as it can
become it still is warm, and on a cold day it continues to lose heat
more rapidly than is desirable. It is to prevent this that clothing is
worn. Clothing operates for people as fur does for animals. It
establishes a nonconducting layer between the skin and the outside. This
nonconducting layer warms up to the temperature of the body and so
hinders the escape of heat. The actual nonconducting material is the air
which is caught in the meshes of the fabric, or in the case of
fur-bearing animals among the different strands of the fur. The
effectiveness of clothing for conserving heat depends altogether on the
degree to which it imprisons air in its meshes. In this respect wool is
the most effective of all fabrics, cotton next, silk and linen having
very little effectiveness. This explains why wool is preferred for
winter clothing, linen and silk for summer.
The temperature of the body as a whole is, as we have seen, about 98½
degrees F.; this figure represents the maximum temperature that the skin
can reach, even when it is flushed to its utmost. In the warm weather of
the summertime the temperature of the air frequently mounts to or even
above that point and it is evident that under such circumstances the
body cannot give heat directly from itself to the surrounding air, and
no amount of flushing of the skin will enable it to do so. It is under
these circumstances that the second method of getting rid of heat comes
into play, namely, the evaporation of sweat. We have spoken of the sweat
glands in a previous chapter, but have left their action and the
description of the skin in which they lie for this point.
The skin serves a number of purposes; it is the great protective layer
for all the parts beneath; in order that it may serve for this it must
itself be reasonably free from injury. This is secured by having the
outer layers of the skin composed of a horny dead material. Just beneath
this dead layer is a layer of living cells tightly packed together and
having exposure to the body fluids only at their under side. Cell
multiplication goes on in these cells continuously and rapidly; as the
cells divide, they grow, the result being that those that are underneath
are constantly crowding those above them farther and farther out toward
the surface; this cuts them off from their food supplies and so they
die. This layer of dead cells becomes very closely packed and makes up
what is commonly called the horny layer of the skin or the “cuticle.”
The outer part of this cuticle is constantly rubbing off and, of
course, as this happens any dirt that may be clinging is rubbed off as
well. A large factor of cleanliness is the constant rubbing off from the
surface of the body of its outermost layer. The extent to which this
happens can be appreciated by anyone who has ever had a broken bone and
has had to have an arm or leg put up in a splint or cast for several
weeks. At the end of that time there is a great accumulation of dead
skin waiting to be rubbed off.
Bathing is a very efficient aid to cleanliness; when baths are for this
purpose, warm or hot water, with an abundance of soap, should be used;
the choice of soap is an individual matter determined largely by the
sensitiveness of the skin. Chemically there is no very great difference
between one kind of soap and another. Some of them contain materials
which are more irritating than those found in others and are to be
avoided by persons whose skins are easily irritated. The common belief
that a bath should not be taken immediately after eating rests on the
feeling that the flushing of the skin that results from the contact with
the warm water may divert blood unduly from the alimentary tract and so
interfere with the process of digestion. This may very well be true if a
very hot bath is taken; where the bath is only a degree or two above
body temperature little trouble is to be feared from this cause. A cold
bath shortly after eating sometimes gives rise to cramps either in the
stomach or in the muscles. Not much is known about these cramps or about
the causes which bring them about. In connection with its use as the
protective surface of the body the skin has scattered over it numerous
glands known as the _sebaceous glands_, which secrete an oily substance
that is spread more or less completely over the skin. This oil probably
helps to keep the skin soft and also to some degree to make the skin
waterproof. One of the reasons why soap has to be used in bathing is to
dissolve off this thin film of oil which is ordinarily over the surface
of the body.
Another use of the skin is as a great sense organ; as we have already
seen, the structures for touch, for temperature, and for pain are
present in the deeper layers of the skin. These consist of tiny cell
masses into which the tips of the sensory nerves pass. In the case of
the nerves of pain there are believed to be no special end organs, but
the nerves end nakedly among the cells of the skin.
The third use of the skin, and that with which we are particularly
concerned here, is as the fine regulator of body temperature. We have
already seen in part how the skin works in this connection, through
being warmer when there is more blood flowing through it and cooler when
there is less. Its other heat-regulating mechanism is made up of the
_sweat glands_. These, as the name implies, are tiny glands in the skin;
they consist of tubes opening on the surface and at their inner end
coiled up into a sort of knot. In this knot are a great many fine blood
vessels, so that each sweat gland has an abundant blood supply. So far
as we can tell, the sweat glands act as filters, corresponding in that
respect to the filtering tips of the kidney tubes. One interesting thing
about them is that the filtering action is controlled by nerves. These
nerves belong to the system which controls the smooth muscles and
glands; when the nerves become active the sweat glands are also active,
and there is rapid filtration of water and inorganic salts from the
blood into the sweat glands and out to the outside of the body. Small
amounts of organic materials come out also in the sweat, and these are
responsible for its characteristic odor. They evidently differ in
different people, since all dogs and some persons are able to recognize
individuals by their odor, and body odor is largely the odor of sweat.
The sweat glands are carrying on their filtering activity most if not
all of the time; we are not usually aware of it because the sweat comes
out in exceedingly fine drops which evaporate as fast as they are
formed; it is only when the sweat is poured out faster than it
evaporates that we become aware of its presence. If the air is very full
of moisture, sweat will stand on our bodies even though it is not being
formed more abundantly than usual. This is because of its inability to
evaporate into air already laden with moisture. Usually, however, when
sweat appears on the surface of the body it is because the sweat glands
have become more active. A couple of paragraphs ago we saw that the
sweat glands are under the control of nerves; these arise like the other
nerves that control smooth muscles and glands from a center in the brain
stem; this particular one is called the sweat center. It may become
active through various influences. The one most commonly arousing it is
a rise in the temperature of the blood. Whenever we begin to exercise,
heat is produced very rapidly, warming up the tissues in which the
activity is going on and, since the blood is flowing through them
rapidly, warming the blood up as well. This warm blood circulates all
through the body, tending to raise all parts of it to the temperature
of the active regions, or, as it passes through the skin, to cool by
loss of heat from the surface. When this warm blood enters the brain
stem it arouses the sweat center and an increased secretion of sweat
results. The importance of this is that the evaporation of water, no
matter at what temperature, requires a large amount of heat. This heat
is abstracted from the nearest place, which in this case would be the
body itself, so that the evaporation of sweat acts powerfully to cool
off the body. In hot weather this is really our only effective means of
getting rid of heat, for if the body is no warmer than its surroundings
it cannot lose heat directly, but sweat can evaporate, taking heat with
it, no matter how warm the surroundings may be. We said a moment ago
that a high percentage of water in the air would hamper the evaporation
of sweat. The practical workings of this fact are seen in connection
with heat prostrations in the summertime. Careful scrutiny of the
weather reports will show that these are much more numerous as well as
more severe on days of high relative humidity than on days that are
simply hot, but without much moisture in the air. As the sweat
evaporates from the body, the resulting water vapor has a tendency to
linger in the neighborhood and so to interfere with further evaporation.
Under these circumstances it is desirable that this moisture-laden air
be moved away and fresh air brought into its place. This is the benefit
we obtain from fanning. The air that is brought upon us by a fan feels
cooler than it really is; this we realize when we notice how comfortable
the draft of a fan is even on the very hottest days. When one fans
oneself in the old-fashioned way, the heat produced in working the fan
is often almost enough to balance the loss through the improved
evaporation of sweat. An electric fan, on the other hand, is a very
powerful aid to comfort in hot weather. In fact it is hard to think of
any mechanical device that has contributed more in recent years. An
amusing illustration of the importance of moisture in the air in
relation to bodily comfort is in the case of the man who thought he
would obtain a cool-weather office in hot weather by installing a block
of ice and causing his electric fan to play upon it. Very much to his
surprise and quite contrary to his expectations the room quickly became
unbearably sultry. The rapid evaporation of the ice filled the air so
full of water vapor that evaporation of sweat could not take place and
the persons in the room were much worse off than if they had contented
themselves with merely keeping the warm and comparatively dry air of the
room in rapid motion. Although the evaporation of sweat is a very
effective means of getting rid of heat from the body it does not work
perfectly in times of great muscular exertion in very hot weather.
Careful studies of men in steel industries and other places where hard
work is done in intense heat have shown that the production of heat
during the course of the working day slightly out-strips its loss, so
that by the end of the day it is the regular thing for the body
temperature to be up two or three degrees, to 100 or 101 degrees
Fahrenheit. Upon finishing the work the temperature quickly falls to
normal, so that there is no reason at present for supposing this daily
rise to be seriously harmful.
In fever the production of heat becomes greater than its loss for a time
and so the temperature goes up. It must not be forgotten that presently
the loss again balances the production; if it did not, the temperature
would keep on rising until death resulted; usually the greater loss of
heat from the body at the fever temperature is sufficient to restore the
equilibrium, but it will be clear that the temperature cannot fall again
until the heat loss exceeds the heat production. There has been a good
deal of discussion as to whether fevers are caused by an increase of
heat production or by an impairment of the machinery for getting rid of
heat. There is no doubt that in fevers the resting metabolism is much
greater than in health; it is not by any means always the case, however,
that the total metabolism of an individual lying quietly in bed with a
fever is greater than that of a healthy individual doing heavy manual
labor. We must therefore look to an interference with the process of
losing heat to account for the rise in temperature. The distribution of
blood through the skin in fever does not differ from that at other times
when the body is warm; it is the usual thing in fevers for the skin to
be much flushed. There is, on the other hand, a definite impairment of
the sweat-secreting mechanism. It is one of the most familiar facts
about fever that the skin is not only hot but very dry. It is also well
known that by inducing sweating the temperature can often be brought
down. It is evident that the poisons which are responsible for the fever
have at least two effects; to increase general resting metabolism to a
high level and at the same time to interfere with the ordinary
regulation of the sweat glands, so that, even though the temperature of
the blood is several degrees above normal, the sweat glands are not
stimulated to active production of sweat.
A fever is very uncomfortable to the person suffering from it, but is
not in itself particularly dangerous, unless it mounts to a very high
degree. The body wastes away rapidly, of course, because of the
increased metabolism which is usually not balanced by any taking of
food. Theoretically fever patients should eat as abundantly as laborers;
practically this is impossible of accomplishment in most cases because
of the depressed condition of mind and body of the patient. In some
particularly wasting diseases, like typhoid, feeding has been carried on
with some degree of success. The old practice with regard to fevers was
to restore the patient to comfort as quickly as possible by getting rid
of the fever, that is, by lowering his temperature to normal; at the
present time the tendency in medicine is not so much to strive with the
result of the poisoning as to seek to rid the body as quickly as
possible of the poison and of its source. For that reason modern
physicians are much less concerned with the degree of fever shown by the
patient than with the extent to which the poisons in his body are being
controlled or are becoming masters.
In all our discussion of the regulation of body temperature it is
important to remember that our feelings of cold or of warmth depend
altogether on the temperature of the outermost one-quarter inch of our
body surface. No matter how cold or how warm we may feel, as soon as we
get to that depth below the surface, we find the body temperature the
same, namely 98½ degrees. We feel cold when the skin is cool; the skin
is cool because not much blood is flowing through it; the stimulation of
the surrounding cold on the skin has aroused reflex vasoconstriction and
so diverted the blood out of the skin into other parts of the body.
This means that the mechanism for preventing loss of heat is working as
effectively as it can and, therefore, that the heat which the body
produces is being conserved. Experience shows that in reality the
feeling of cold is very largely a matter of the condition of the
extremities. If the hands and feet are warm, one rarely finds the cold
uncomfortable; on the other hand, cold extremities produce a very
general feeling of discomfort, even though the rest of the body may be
warm. The lesson to be drawn from this is to pay particular attention to
keeping the extremities warm. Where workmen are standing on a floor it
is much more important that the floor be warm than that the air of the
room as a whole be so. Of course, it must not be cold enough to allow
the fingers to be chilled and stiff where manual work is being done, but
it has been found that a considerably lower factory temperature is
endured when the floors are warm than when the floors are cold.
We feel cold in cold weather because the body is conserving heat; in
warm weather, on the other hand, we feel warm because the skin is
flushed and the body is losing heat as rapidly as it can. The practical
bearing of this is that it might be disastrous to feel particularly warm
in cold weather. Not, of course, if the feeling of warmth be due to a
very rapid production of heat, as in vigorous exercise, but if it is due
simply to a flushing of the skin when not much heat is being produced,
the body is being deprived of what heat it has and a condition which
cannot long be endured in cold weather will result. It happens that
exactly this situation is met with in connection with the use of
alcohol. One of the important effects of alcohol is to produce a
flushing of the skin; this is a direct drug effect and has nothing
whatever to do with the amount of heat that is being produced in the
body. The result is that one who, by a few drinks, fortifies himself,
when starting out for a long cold ride, feels very warm and comfortable
as long as the alcoholic effect persists; but as soon as this passes off
he is very much colder than he otherwise would be, since during all this
time he has been losing heat rapidly instead of conserving it. It used
formerly to be not at all uncommon in the cold parts of the country for
persons to perish from exposure on long drives because they had
attempted to keep themselves warm by taking alcohol, when if they had
conserved their bodily heat instead of wasting it for the sake of
comfort, they would probably have reached their destinations in safety.
While we are on the topic of temperature regulation and the part played
by the skin generally in bodily activities a word should be said about
bathing for other purposes than cleanliness. There is a good deal of
discussion about whether the morning cold bath is really a health
measure or is simply a fad; there can be very little doubt that persons
who react well to the cold bath find that it contributes definitely to
the enjoyment of life. It is particularly true that after a night of
disturbed rest the morning cold bath makes one feel much more ready for
the duties of the day, whether he actually is so or not. The value seems
really to be in what is known as the _reaction_ in which the first chill
is followed by a warm glow. The bath should under no circumstances be
prolonged beyond the time when a good reaction is obtained. Brisk
rubbing with a harsh towel helps the oncoming of the reaction very much.
For those who would like to take a cold bath but have found it too much
of a hardship a hint may be helpful, namely, that if one enters the bath
with the feet warm there is practically no discomfort connected with
taking it. To step into a cold bath when the feet are already cold
causes them to begin aching almost instantly and usually nullifies all
the benefits the bath affords. One should either enter the bath
immediately after rising, before there has been any time for the body to
become chilly, or if one prefers to shave or carry on other activities
first, it is a good plan to give the feet a momentary preliminary bath
in hot water. When this condition is fulfilled, the cold bath will be
both enjoyable and beneficial to the majority of people. Very hot baths
have a distinct relaxing effect; they favor the onset of sleep and can
be taken to best advantage just before retiring. There is nothing in the
common idea that a hot bath opens the pores of the skin; the only pores
the skin has are the openings of the sweat glands, and these do not vary
in size. What a hot bath does do, is to cause a marked flushing of the
skin as the result of which the body loses heat rapidly. It is
necessary, therefore, after a hot bath to wrap oneself warmly so that
excessive loss of heat shall not occur.
In finishing this topic, the subject of catching cold must be brought
up, together with its relation to the regulation of body temperature.
There is no doubt at the present time that common colds result from
infection; in that sense they are acute diseases. It seems to be the
fact, however, that the organisms which cause them are pretty constantly
present in the air passages of our throats and lungs ready to invade the
body whenever opportunity offers. Very recently it has been shown that
rapid chilling of the skin is accompanied by contraction of the blood
vessels in the linings of the throat and air passages. The effect of
thus cutting down the blood supply to these linings seems to be to make
them more ready of access by the organisms of colds. At any rate the
fact that when the skin is suddenly chilled a cold frequently develops
is best explained on this basis. Since colds are infectious, the
organisms causing them may sometimes succeed in penetrating the linings
of the air passages even when no change in the latter has occurred. It
may therefore happen, and frequently does, that one develops a cold
without being able to refer it to any time when there was a sudden
chilling of the skin. Also it can easily happen that the chilling may
not lead to a cold, since if the organisms do not happen to be abundant
or if the general bodily resistance is high, the infection will not get
a foothold, even though the linings of the air passages would permit the
organisms to enter. One’s best precaution against colds would naturally
be to avoid having the organisms which produce them present in the
throat and lungs. Since this usually cannot be done, the remaining
practical measures are to keep the general bodily health as good as
possible and to avoid conditions which lead to a sudden rapid chilling,
such as sitting in a cold draft when heated.
CHAPTER XX
THE PERPETUATION OF THE RACE
We have tried to take up one by one the chief things that happen in the
body, but thus far have emphasized their importance entirely in
connection with bodily well-being; that is, we have seen how the body
maintains itself against the competition of other living things and in a
world full of hazards. Before leaving the subject entirely, a short
account must be given of the way in which the _race_ is maintained upon
the earth as distinct from the maintenance of individuals. Early in the
book we showed that every one of us starts life as a single cell which,
by dividing and subdividing, along with continuous growth, finally
develops into our large and complicated body. This cell is really the
union of two cells; one furnished by each parent; in the body of the
parent it formed part of what is known as the _germinal tissue_, this
name being applied because the cell from which we start may be spoken of
as the germ of life. As the cell from which the body is to come begins
to develop, the cells formed from it quickly become different one from
the other, so that very early it can be distinguished that certain cells
are to form the future nervous system, others the future muscles, and so
on. One of the earliest of these groups of cells to become
distinguishable is that which is to become the germinal tissue in the
newly formed individual. A great deal of importance has been attached
of recent years to this fact that the germinal tissue is set aside
almost from the beginning of development, and when we remember that the
next generation will be derived from this germinal tissue and from no
other tissue, we see that there is a very close relationship of the
germinal tissue from generation to generation. The importance of this is
in connection with heredity, namely, with the question of the
resemblance of the child to the parent. We all know that sometimes
children resemble their parents very closely, at other times there is
almost no resemblance at all. The main fact of heredity is, as we have
just seen, that the child comes from germinal tissue of the parent and
not from the parent as a whole. We can think of an individual as a
complex body carrying within itself and nourishing an independent group
of cells which are to serve as the starting point for the next
generation, but with which the individual himself has nothing to do
except to provide nourishment. A little later we shall try to show just
why we think of the germinal tissue as so little dependent on the rest
of the body. What we want to do first is to point out how this notion
must affect our views of heredity. If the germinal tissue is simply
harbored and nourished by the body, but otherwise quite independent of
it, it follows as a matter of course that things the parent does,
provided that they do not disturb the nourishment of the germinal
tissue, can have very little effect upon it. For example, anything that
the parent may achieve during his lifetime cannot be passed on by
heredity to his offspring. This is entirely contrary to the idea of
heredity which is held by nearly everybody. Just a little over one
hundred years ago a Frenchman by the name of Lamarck published writings
in which he argued very strongly in favor of the inheritance of
“acquired characters,” meaning by this that the achievements of parents
could be and were transmitted to the offspring. It is evident that this
would be a very great advantage; the progress of the race would be
secure if the children could inherit directly the achievements of their
parents. Of course, it might work the other way around and children
might inherit unfavorable acquisitions of their parents as well as
favorable. Since the time of Lamarck there has been not only hot
discussion of his ideas but also a vast amount of experimentation to
find out whether acquired characters actually can be inherited. One of
the most famous experiments is that of a man who cut off the tails of
mice at birth and did this generation after generation in the hope of
being able to produce a race of tailless mice; after a great many
generations he abandoned the attempt with the conclusion that the
artificial removal of tails from parents would not cause the offspring
to be born in the tailless condition. More recently similar experiments
have been carried out on kinds of animals that have much shorter lives
and in which the generations are correspondingly more frequent. In some
cases thousands of generations have been studied without any indication
that changes brought about during the lifetime of the parents can be
transmitted to the offspring.
One of the first questions that is sure to be asked as soon as this
inheritance of acquired characters is denied, is how changes can then be
brought about; the answer to that question is found in the experience of
animal and plant breeders. One fact of nature which should be
emphasized, is that individuals are never exactly alike except perhaps
in the case of so-called identical twins which have a special heredity
spoken of in Chapter V. Even brothers and sisters always have pretty
marked differences. These differences among individuals are some of them
probably more or less accidental results of the way in which the germ
develops into the complete body; others are the result of differences in
the germ cells themselves. The distinction between these is that where
the germ cells are different, the difference will be transmitted by
heredity to future generations; if it is a modification that comes on in
connection with development and is not due to a difference in the germ
cell, it will not show itself in future generations. What the animal and
plant breeders have to do is to watch for changes in their stock, and
when the kinds that they are looking for appear, they breed them in the
hope that the desired features will prove to be hereditary, so that a
race can be established showing them. A very striking example of this
kind of breeding is in the development of hornless cattle. Of late years
it has been the practice to dehorn cattle regularly and this dehorning
has never caused the offspring to be born without horns, but on the
other hand it has happened occasionally that calves have been born which
were naturally hornless and since this absence of horns was due to a
difference in the germ tissue, the character was found to be hereditary
and it has been possible to establish breeds of hornless cattle. Thus by
selecting cases where a change occurred naturally in the germ tissue, a
result has been obtained which could not possibly be gotten by any
amount of work directly upon the parents.
What we have tried to make clear thus far is that heredity is absolutely
a matter of the condition of the germinal tissue. What we have now to do
is to see what the germinal tissue is like and how the process of
heredity actually goes on. In Chapter V something was said about the
nucleus; it will be remembered that the nucleus contains a substance
known as _chromatin_, which, as seen under the microscope, looks like a
tangled skein or network of fine threads, but is in reality a number of
tiny structures known as _chromosomes_. We now know that these
chromosomes are the actual controllers of heredity. Of course we do not
know at all how they exert their control; what we do know is that when
certain factors are present in the chromosomes of the germinal tissue of
the parents, the offspring derived from that germinal tissue will have
traits that would not be present if the chromosomes had been different.
Space does not permit us to tell at length how the facts that are now to
be described were discovered. They date from the gardening experiments
of an Austrian monk by the name of Mendel, who for many years grew
ordinary garden peas and studied from season to season the varieties
that appeared. The facts of heredity that he found to be true of peas,
have since been shown to apply just as well to ourselves, and since this
book deals with human beings we shall try to make the description apply
directly to human heredity. The first thing to get clearly in mind is
that every single thing about any one of us which can or does differ
from the corresponding feature in another person, may be a _hereditary
trait_, and, if it is, will have a factor controlling it somewhere among
our chromosomes. Since the number of hereditary traits is legion,
including not only the size and shape of all parts of our bodies inside
and out, but our mental peculiarities and moral tendencies as well,
there must be a huge number of controlling factors, or _determiners_, as
they are often called. As a matter of fact, there are probably not quite
so many determiners as traits, because a single determiner may govern
more than one trait. But even so, the number of determiners is too large
for comfort in trying to describe their working. The best way to go
about it is by pretending that we are not so complicated as we really
are. We shall do this by setting the number of different determiners
human beings may possess at fifty-two, not because that is anywhere near
their real number, but because it is the number of combined large and
small letters in the alphabet, and we propose to use letters to stand
for determiners, as an easy way to keep them separate in the
description.
Every cell in our bodies has its nucleus with its equipment of
chromosomes. An interesting fact already spoken of in Chapter V is that
according to our best knowledge the chromosomes in any cell of any one
of us are exactly like those in all the other cells of the same person.
The chromosomes in the muscle cells are exactly like those in the nerve
cells, and both correspond exactly with the chromosomes of the ordinary
cells in the germinal tissue. In every one of these cells the
chromosomes are arranged in pairs. It happens that in human beings the
number of pairs is twenty-four, with one pair incomplete in some of us
for a reason that will be explained presently; this is an awkwardly
large number for our present purpose, since we have allotted only
fifty-two determiners altogether, so we shall do some more pretending
and set the number of pairs at nine. One more change will have to be
made from the real state of affairs before we can go on with the
description; this is to suppose that our various bodily features can
show only one difference, instead of the many of which they are really
capable. For example, we shall suppose that the hair can be either black
or light, but never red; the nose can be Roman or Greek, but never
Irish. By making this supposition, we can let the large letters stand
for one set of hereditary determiners and the small for the same
features but with exactly contrary traits. According to this
arrangement, if we had two persons side by side one of whom had only
large-letter determiners in his chromosomes and the other only small,
they would have the same general human make-up, but in every possible
detail one would be the exact opposite of the other.
It has been proven by complicated studies which we cannot take time to
describe that the determiners are grouped in the different chromosomes
in a definite plan. We saw a moment ago that the chromosomes are in
pairs. This pairing is an essential part of the arrangement, for every
hereditary bodily feature actually has two determiners governing it,
which lie in corresponding positions in the two chromosomes of the pair.
To illustrate how this works out, let us suppose that the chromosomes of
the first pair contain determiners A, B, and C. Each of these three
determiners will be present in both members of pair number one, and if
this is true of any cell it will be true of all the cells, and in any
other human being either they or the corresponding small-letter
determiners, a, b, and c, will occupy pair one of the chromosomes.
Furthermore, they will lie in a row within the chromosomes, always in
the same order; thus if A and C are at the ends with B in the middle in
one chromosome, every other chromosome that contains these three
determiners will have them in the same order.
[Illustration: DIAGRAM ILLUSTRATING VARIOUS ARRANGEMENTS OF DETERMINERS
IN A SINGLE CHROMOSOME PAIR
1 and 2, Pure; 3, Hybrid.]
Thus far we have planned our diagrams as though only large letter
determiners were concerned; but we saw a moment ago that there is a
complete set also of small-letter determiners, which control a set of
contrary hereditary traits, and we intimated that these will sometimes
be found in the chromosomes in positions corresponding with those
occupied by the equivalent large-letter determiners. It might happen,
for example, that pair one of the chromosomes would contain large-letter
determiners A, B, and C, while pair two would contain small-letter
determiners a, b, and c. Evidently the person in whom this combination
was present would differ from one all of whose chromosomes contained
large-letter determiners, since part of his traits would be established
by small-letter determiners.
We are now ready to go back to the germinal tissue and trace the process
of heredity as it actually works out in the developing offspring. In the
ordinary cells of the germinal tissue, as we have already seen, the
chromosomes are exactly like those in the other cells of the body. Cell
multiplication goes on actively in the germinal tissue of both parents;
in the mother this leads to the production of germ cells which are
called eggs, and in the father to the production of cells that are
called sperm. During the process certain changes occur, so that neither
eggs nor sperm are exactly like the original cells of the germinal
tissue. If we look back at the description of cell division in Chapter
V, we shall recall that the chromosomes split lengthwise and are pulled
apart. Now that we have learned about determiners, we will realize that
every determiner splits in half, because otherwise there would not be an
equal distribution of determiners between the two cells. Much of the
cell division in the germinal tissue is precisely like this, but at a
certain stage in the production of both eggs and sperm there is one cell
division in which the pairs of chromosomes are simply pulled apart,
without there having been any previous lengthwise splitting. The result
of this is to leave the resulting cells with only half as many
chromosomes as the other cells of the body have. Some further changes
take place in these cells before they become ripe eggs or ripe sperm,
but there is no further disturbance of the chromosomes, so that eggs and
sperm contain only one member of each pair, instead of both members, as
do all other body cells.
The first step in development is the coming together of the egg cell
with one sperm in the process that we call fertilization. The sperm
penetrates the egg and its chromosomes line themselves up with the
egg’s, restoring the pairing that is present regularly. Immediately
afterward the cell divisions begin that make up development, and in all
of these the usual lengthwise splitting of determiners takes place.
Every cell in our body contains its pairs of chromosomes, one member of
each pair tracing back directly to the egg cell while the other traces
directly to the sperm. Thus half of our determiners came from the
maternal germ tissue and half from the paternal.
[Illustration: CHROMOSOMES IN CELL DIVISION
Figure 1, chromosome splitting in ordinary cell division, in which each
determiner splits in half, contrasts with Figure 2, reduction division,
in which the chromosomes of the pair are simply pulled apart.]
We shall now begin to see how heredity works out. Suppose chromosome one
in the egg has large-letter determiners A, B, and C, while the
corresponding chromosome in the sperm has small-letter determiners a, b,
and c. When these line up after fertilization, restoring pair one, we
have A opposite a, B opposite b, and C opposite c. Since we have
supposed the large and small letters to stand for contrary hereditary
traits we introduce here a conflict and must ask at once how it is
settled. One of the things the monk Mendel worked out in his studies of
heredity in peas was this particular problem. He found that where there
is conflicting heredity one of the determiners usually dominates over
the other, and when this happens the trait in the offspring will be like
that of the parent which contributed the dominant determiner. To
illustrate: suppose A is dominant over a, then in the case in question
the offspring will be like the mother in feature A. In some kinds of
animals and plants conflicting characters blend in the offspring,
producing an intermediate appearance. A good example of this latter case
is in the common flower, the four-o’clock. In this plant white blossoms
and red blossoms are due to determiners that occupy the same positions
in the chromosomes; therefore, if white and red flowered plants are
crossed, these conflicting determiners come together when the sperm and
egg chromosomes pair. Since neither determiner dominates over the other,
the color of the flowers in the offspring is neither white nor red, but
pink.
Any individual whose chromosome pairs contain conflicting determiners is
called a “hybrid”; there may be every degree of hybridism, from the
simplest, in which all the chromosome pairs are alike except one, up to
the most complete, in which all the pairs are unlike. It is easy to tell
a hybrid by its appearance in the cases in which there is blending
inheritance, but not so easy when one trait dominates over the other,
for then the hybrid will look like the parent that furnished the
dominant determiner. The sure way to detect hybrids is by the study of
their offspring. Suppose we have two parents, both of whom are hybrids
in respect to chromosome pair one. This pair in both will contain
determiners A, B, and C lined up opposite a, b, and c. Since we have
supposed the large letters to be dominant over the small, both will have
the same appearance, dependent on the presence in their chromosomes of
A, B, and C. Since in the formation of eggs and sperm the chromosome
pairs are pulled apart, half the eggs produced by the mother will
contain determiners A, B, and C, and the other half a, b, and c, and
half the sperm of the father will similarly contain one set and half the
other. Since it is an absolute matter of chance which sperm encounters
which egg in fertilization we can safely conclude that in the long run
all the chances will be realized equally. Calling, for convenience, the
large-letter eggs E and the small-letter e, and, similarly, the
large-letter sperm S and the small-letter s, this means that E can be
fertilized either by S or s, and e also by either S or s. The possible
combinations are ES, Es, eS, and es. In terms of actual determiners
these combinations are ABCABC, ABCabc, abcABC, and abcabc.
The combinations just given represent the possible offspring from a pair
of hybrid parents. If we look them over, we see at once that only half
of them are hybrid, namely, combinations ABCabc and abcABC; the other
half are pure breed, the chromosome pairs being exactly alike; but these
pure breeds are of two kinds, one having only large-letter determiners,
the other only small-letter. If it is a case where the large letters
dominate over the small, the large letter pure breeds and the hybrids
will look alike, but the small-letter pure breeds will look different,
since in them the traits governed by the small-letter determiners have a
chance to show themselves. A very good illustration of this is seen in
eye color in human beings. Brown eyes are dominant over blue; in other
words, the determiner that causes eyes to be brown dominates over that
responsible for blueness in cases where both come together in hybrids. A
person who has brown eyes may be either a pure breed in that respect or
may be a hybrid; there is no way to tell the difference from the
appearance; but if the brown-eyed person has offspring, and any of them
turn up with blue eyes, it is proof positive that the parent is a hybrid
so far as eye color is concerned. Moreover, the blue-eyed child is not a
hybrid in this respect; his brown-eyed brethren may or may not be; in
the long run two-thirds of them will prove so; the other third will be
pure breed, having in their chromosome pairs only brown-eye determiners.
Where the hybrids differ from the pure breeds, as in the case of the
four-o’clocks, given earlier, it is easy, of course, to tell which are
pure and which are hybrid. When pink four-o’clocks are interbred, the
chromosomes will combine just as described above for hybrids, since the
plants that have pink flowers are hybrid. One-half the offspring will
have pink flowers, showing that they are hybrid; one-fourth will have
white flowers, proving that in them the white-flower determiners have
separated out, and the other fourth will have red flowers, because in
them the red-flower determiners are the only kind present. This and
similar experiments have been tried hundreds of times, and whenever the
numbers of offspring have been great enough to allow the chances to
equalize, the proportion of different kinds of offspring has always
agreed almost exactly with expectation. Of course in human beings the
families are not large enough for this always to work out accurately,
but even so the agreement is often striking.
[Illustration: CARING FOR THE BABY’S EARS
Important for adults and babies alike]
[Illustration: THE BABY’S FOOTPRINT
A means of positive identification]
[Illustration: BABIES PHYSICALLY AND MENTALLY ACTIVE]
In practical animal breeding the blended inheritance just described is
not very useful, for even though a blended character might appear which
is just what the breeder has been looking for, it will not occur in more
than half the offspring and can not ever be depended on to show itself
in any particular individual. This explains largely why pure-bred stock
is always more desirable than hybrid, and why breeders strive so eagerly
to obtain desired traits in pure-bred animals. In plants, blended
characters are much more valuable, for two reasons; first, because the
offspring are so numerous that even though half of them come out pure,
and so lack the desired blend, there are enough left that have it to
make the crop worth while; and second, because propagation by cuttings
is possible in very many kinds of plants, which means that the same
plant is kept going in hundreds of places, and for tens or even hundreds
of years. A trait that is desirable can be perpetuated indefinitely by
this means, even though it may be a blending of several hereditary
traits, which would separate out in a few generations by ordinary means
of propagation.
There are several more things in heredity that must be taken up while we
are on the subject, so we shall have to return to the chromosomes for a
while. We have seen that there are several determiners to each
chromosome; for convenience, we assigned three apiece to our
chromosomes, except the ninth, which has to get along with two; but in
reality the number to each chromosome is often much greater. This
grouping of the determiners, several to a chromosome, carries an
interesting consequence with it, in that all the hereditary traits
controlled by one chromosome have to go together in reproduction. In
the example we have already used A, B, and C are together; therefore any
individual that shows character A must show B and C as well. The most
striking instances of this are certain traits that are bound up with
sex, but we cannot describe these further until we have looked into the
heredity of sex, which we shall do in a minute. First a word must be
said about occasional exceptions that turn up to the rule that we have
just stated. In the study of thousands of specimens now and then one has
been found in which there has evidently been a swapping about of
determiners. We can illustrate the situation by supposing chromosome one
is found to contain determiners A, b, and C, instead of A, B, and C; one
small-letter determiner has traded places with a large. Of course, the
effect of this is to permit different combinations of hereditary traits
than ordinarily occur, and at the present time students of heredity are
actively engaged in following this up to see how it happens, and what
advantage can be taken of it. This crossing over of determiners from one
chromosome to another takes place only among such as are actually in
contact at times within the nucleus as seen under the microscope, which
confines it to the members of corresponding pairs.
In man, and in many of the lower animals, sex is a hereditary character.
That means that there is a determiner for it which is grouped with other
determiners in one of the chromosomes. In man the determiner is for
femaleness; there is no special determiner for producing the male sex;
it is produced whenever the female determiner is missing from one
chromosome of the pair, and this is brought about by having the whole
chromosome that should make up this pair absent. At the beginning of
this chapter the fact was mentioned incidentally that a good many of us
have only 47 chromosomes, instead of the 48 that are characteristic of
human beings. The distribution is really almost exactly half and half,
for all males have 47 and all females 48. This means that the cells of
the germinal tissue of females have 24 complete pairs, while the
corresponding cells in males have only 23 complete pairs and one
chromosome over. This extra chromosome is the one that contains the
determiner for femaleness; each of the chromosomes of pair 24 in females
contains this determiner also. These are often spoken of as sex
chromosomes.
Now when in the course of the production of egg cells within the
mother’s germinal tissue the pairs of chromosomes are pulled apart, each
separate cell, and so each egg, will contain the full number of
chromosomes, 24, including the sex chromosome. But when the same thing
happens in the course of the production of sperm only every other one
will have the full number; the remaining half having only 23, and all of
this half lacking the chromosome that contains the determiner for
femaleness. There are, then, always equal numbers of two kinds of sperm,
one with 24 and the other with only 23 chromosomes. If the egg is
fertilized by a sperm containing 24, including the sex chromosome, the
pairing of chromosomes is complete in the egg, and the offspring will be
a female; if, on the other hand, the fertilizing sperm is one that
contains only 23 chromosomes the pairing in the egg will be incomplete;
the single sex chromosome of the egg will not be paired with a
corresponding one from the sperm and the egg will develop into a male.
Since it is a pure chance whether fertilization will be accomplished by
a sperm of 24 or one of 23 chromosomes, we should expect the sexes to
appear in exactly equal numbers, taking the world as a whole. As a
matter of fact, whenever extensive birth data have been accumulated they
have shown a very slight excess of male births over female. We are not
able to explain this at the present time. It is possible that the 23
chromosome sperms are a little more vigorous for some reason than those
that have 24, and so are able to fertilize slightly more than their
share of eggs.
We spoke a moment ago of hereditary traits whose determiners are bound
up in the sex chromosomes. All such behave interestingly in heredity for
the simple reason that they can never be transmitted from father to son,
but only from father to daughter. This is because, as we have just seen,
the sex chromosome in the sperm always causes the egg which that sperm
fertilizes to develop into a female. The single-sex chromosome which
males possess invariably comes from the mother. An interesting example
is the common type of color blindness known as Daltonism. Normal color
vision is hereditary and the determiners which establish it are in the
sex chromosomes. Occasionally a person is found in whom these
determiners are defective. If this person is a male, he will be color
blind, but if a female not, unless both sex chromosomes are defective in
this regard, since normal color vision is dominant over color blindness;
so if one sex chromosome is normal the vision will be also. The woman,
in this case, will be a hybrid with respect to color vision; one of her
sex chromosomes containing a normal determiner, the other a defective.
This works out in heredity as follows: If a color-blind man is married
to a woman who has no color blindness in her heredity, none of his
children will be color-blind because he cannot transmit the sex
chromosomes which carry the determiners for color blindness to his sons,
but only to his daughters; all the latter will be hybrid with respect to
the character, since all of them come from fertilized eggs which
received sex chromosomes from the sperm. If these daughters, in turn,
marry men who are free from color blindness, some of their sons may be
color-blind, but none of their daughters can be. The only way in which
women can be color blind through inheritance is by descent from
color-blind fathers and from mothers who are either themselves
color-blind or are hybrid with respect to the trait. The result of this
difference in the heredity of the two sexes is to make color blindness
many times as frequent among men as among women. In round numbers four
men out of every hundred have this type of color blindness, while only
six or seven women in ten thousand show it.
We have left for discussion only one topic dealing with heredity, but
this is the most baffling of all, since it deals with the problem of how
the various kinds of determiners came into existence. It is evident that
if given one parent with all large-letter determiners and the other with
all small-letter, we might, in the course of many generations, get a
great variety of combinations and so a great many different-appearing
individuals. But unless we have various kinds of determiners to start
with, there is no way in which this can be done. We do not pretend to
know very much about how the innumerable determiners that are in
existence came about, but we have one clue that is thought to point the
way. In some animals, and many plants, descendants put in their
appearance from time to time that are so different from their ancestors
as not to be accountable according to ordinary laws of heredity. These
have long been known, and the name of “sport” has been applied to them
by breeders. Since the facts about determiners have been learned, it has
been clear that these “sports” cannot have all their determiners like
those present in their parents, and it has come to be believed that
occasionally spontaneous changes take place within individual
determiners. Since the determiners are undoubtedly complex chemical
structures, we know of no reason why this might not happen. Probably it
is much more common an occurrence in some kinds of plants and animals
than in others. The name of “mutant” has been applied to the plant or
animal in which this has happened, and the process is called “mutation.”
It is important since it is the most likely way in which the innumerable
kinds of determiners that are now in existence came into being.
We suppose that since life first put in its appearance on the earth
there have been uncounted mutations, a vastly greater number than are
now represented by determiners. Many of the mutants could not compete
with their brothers and sisters of ordinary descent and so promptly
died, but occasionally it might happen that a mutant would be as well
fitted for life as its relatives, in which case it would establish
itself, and in course of time become ancestor to a whole line like
itself. If this happened often enough, and time were allowed for it to
work out, all the kinds of plants and animals that are now in existence
might have come by descent from a very few ancestors. The geological
history of the earth shows that there has been plenty of time, even
though valuable mutations did not occur oftener than once in a thousand
years.
Our description of racial perpetuation should be finished by an account
of the development of the fertilized egg. Snugly ensconced within the
body of the mother, in an organ devoted solely to the purpose, the egg
passes rapidly through the early stages, living at first on fats and
proteins stored within itself. After these are exhausted it draws
supplies from the body fluids of the mother. In the course of a few
weeks it has developed its own conveyer system, with its own beating
heart and its own stock of blood. There is never any actual mingling of
the blood of the developing child with that of the mother; capillaries
of the maternal circulation come into intimate contact with capillaries
of the circulation of the child. Here interchange of all sorts of
material goes on; food and oxygen pass from the mother’s blood to the
child’s and waste materials from the child’s blood to the mother’s.
During all this time the mother is eating, breathing, and excreting
wastes for two. She cannot bring any nervous influences to bear on the
developing child, since there is no connection between her nervous
system and the child’s; she can, however, influence it chemically
through the blood. Poisons that get into the blood of the mother can
pass from it into the blood of the child. These may be the poisons of
auto-intoxication, or drugs that the mother has taken. In either case
they may do the child harm. We do not know very much about this, but it
may be that a considerable percentage of children that are born with
abnormalities that are not hereditary come by them through chemical
influences received from the mother’s blood.
When the development of the child has gone far enough so that it can do
its own breathing, feeding, and discharging of waste materials, it is
expelled from the body of the mother in the process that we know as
birth. This does not imply by any means that parental care and
responsibility are at an end. Food, protection, and warmth must be
provided. Education must be attended to, for the nervous system of the
new-born infant is absolutely undeveloped. It has, through heredity,
certain possibilities of achievement; their realization hinges upon the
bringing to bear of worth-while influences. Upon the attainment of
maturity the child will be expected to assume his place in society, and
society has a right to the best that he is able to offer. In preparation
for this it is the duty, both of the parents and of society itself, to
provide throughout the formative years as nearly as possible the
environment best suited to the development of those traits which make
for usefulness. Environment cannot overcome the limitations of heredity,
but environment can bring out the best that is in us.
CHAPTER XXI
CHILD AND MAN
Everyone is familiar with the beguilingly helpless picture the tiny baby
presents. The disproportionately large head, with aimlessly rolling eyes
and toothless mouth, the frail and delicate limbs, waving in the air or
clutching spasmodically at anything within reach, the expressionless
face, on which, for the first few days, only sensations of discomfort
are registered, all mark a creature whose survival hinges absolutely on
unremitting care; a far cry from the competent self-sufficiency of the
average person of mature years. These surface marks of helplessness are
by no means the most significant. Buried from view beneath the soft and
velvety skin are characteristics of even greater meaning to those on
whom falls the responsibility for the rearing of the new life.
At the time of birth the bony skeleton is very incomplete; there is a
spot just above the forehead where the skull bones have not yet grown
completely together, leaving a space where the brain is protected from
injury only by the overlying skin. This spot can be detected easily in
very young infants by its pulsations in time with the heartbeats. In
most of the other bones the deposit of lime salts to which they owe
their stiffness has gone only a little way, so that it would be
impossible for the child to stand or walk even though it knew how. In
this respect the contrast between the human infant and the new-born of
such animals as horses or cattle is very striking, for the latter walk
stumblingly from almost the moment of birth, and efficiently within a
few hours thereafter.
Not only is the infant devoid of teeth, but in various other regards his
digestive apparatus is undeveloped. Not only is he unable to chew solid
food, but he could not digest most of it if it were served already
chewed. During the early months of life the child is emphatically a
one-diet being. His alimentary tract deals successfully with the mixture
of proteins, fats, and sugars of which milk consists, provided the
proportions are substantially those of mother’s milk and the quantity at
a feeding is not too great. He can do this because the enzymes needed
for digesting these particular substances are manufactured by his
digestive glands from the very beginning, and because the muscles of his
stomach and intestines can churn and propel the soft curd into which the
milk is converted as soon as it enters the stomach. The fact that cow’s
milk sets into a tough curd accounts for much of the difficulty some
babies have in thriving upon cow’s milk.
There is no starch in milk, and neither the saliva nor the pancreatic
juice of the infant contains the enzyme by which starch is digested. It
is wholly useless to begin feeding starch-containing foods until this
enzyme begins to be manufactured, which usually takes place when the
child is about eight months old. Even then the introduction of starch
into the diet should be gradual and cautious.
Modern science has discovered no better food for infants than mother’s
milk, and no substitute more satisfactory in general than suitably
modified cow’s or goat’s milk. Under modern conditions of life,
particularly in cities where milk has to be transported over long
distances, and where much time necessarily elapses before the milk can
be placed in the hands of the consumer, there is serious danger of
contamination of the milk with disease germs. In all enlightened
communities this danger is fully recognized, and the entire milk supply,
so far as possible, but that part of it destined for the feeding of
children in particular, is safeguarded by all available means. A fairly
reliable index to the degree of enlightenment of any community is the
quality of the milk which its children receive. One recent discovery of
considerable importance, and incidentally an interesting illustration of
the way in which correct procedure may be hit upon in advance of the
scientific knowledge which justifies it, is the finding that orange
juice contains one of the dietary accessories, known as vitamines,
essential to health, and present in raw milk, but destroyed when milk is
heated. For years, physicians had recommended orange juice for babies.
It is of vital importance when the milk must be pasteurized.
Both the heartbeat and the breathing in the young child are much more
rapid than in the grown person. It is believed that this quickness of
heart action and of breathing rate are related to the smaller size of
the infant as compared with the adult and are of no very marked
significance. At any rate it is true in general that the smaller the
animal the more rapidly does its heart beat and the more quickly does it
breathe. A very noticeable fact about young children is the
susceptibility to all sorts of influences of the mechanism by which the
breathing is controlled. Every passing interest reflects itself in
heightened breathing. Violent emotion often leads to such extreme
overbreathing as to drain the child’s blood of considerable of its store
of carbon dioxide, whereupon the rapid breathing gives place to
prolonged holding of the breath. Many a young mother has been seriously
alarmed by the length of time her offspring in a tantrum is able to
refrain from drawing its breath. Contrary to the appearance of things,
which would indicate that the child is holding its breath out of spite,
and in the hope of getting even with its parent, the cessation of
breathing is largely or wholly automatic, indicating the way in which
nervous and chemical influences have interacted to suspend the
respiration.
The child is born with all its muscles in place, and all fully formed in
that every muscle fiber the child will ever have has been produced
previous to birth. In fact, as soon as the full equipment of muscle
fibers has been laid down the body loses the power to form more, so that
if, through injury, one is so unfortunate as to have some of his muscle
fibers destroyed he will have to get along for the rest of his life with
those that are left. The gaps in the muscle tissue that are produced by
injuries are filled up by a kind of connective tissue known as scar
tissue. The muscle fibers are all present, but smaller and weaker than
they will be later.
The connections between muscles and nerves are also pretty well
established at the time of birth, so that the body and limbs can be
moved freely, even if not at all efficiently.
Not only are the motor nerves formed and in connection with the muscles
at and even before birth, but the sensory nerves and most of the central
nervous system are ready to begin functioning as well. Some reflex
actions, including a few that require quite elaborate muscular and
nervous coordination, are performed very shortly after birth. One famous
example, that has been much cited as tending to reinforce the belief in
man’s descent from tree-dwelling ancestors, is the curling of the
fingers about a slender rod that is pressed against the palms. In most
very tiny babies the grasp thus secured is strong enough so that the
child can be raised and held in the air, supported wholly by its own
grip. Sneezing, which is really a very complex act, requiring accurate
cooperation on the part of many muscles, is done successfully by very
young infants. The reflex of sucking, which is of paramount importance,
in that without it the child would almost inevitably starve, is present
practically from birth. Another important early reflex is that of
crying. It is a curious thought that this reflex, by which bodily
discomfort is made known, and through which relief may be summoned, is
revealed at the very instant of birth, in connection with the drawing of
the first breath, while the contrary reflex of laughter, by which bodily
well-being is expressed, puts in an appearance only after some weeks or
even months.
It is difficult to determine just how far the sense organs have arrived
in their development at the time when the infant begins its independent
existence. That touch and those senses related to bodily discomfort, of
which pain is most important, are operative from the first is shown by
the occurrence of the reflexes described above, which are brought into
action by those particular senses. There is good reason to believe that
the sense of hunger comes into play within two or three days at the
latest. The sense of thirst does not have much chance to reveal itself
early in life, for with a diet exclusively liquid, and feedings
separated by only a few hours, there is no reason why the child should
become thirsty. As the feedings become less frequent, and particularly
as solid food begins to be added, there is real danger that the child
may be insufficiently supplied with water.
Muscle sense and the equilibrium sense, if present at all, must be in a
very imperfect condition at first. They seem to differ from the senses
described thus far in that they depend on practice for their
development. At any rate the bodily movements are largely aimless in the
beginning, and it will be observed that the baby has the appearance of
experimenting with its extremities, placing them repeatedly in
particular positions and seeming to gain precision thereby. The eye
movements, and especially those by which both eyes are focused on a
single object, depend for their accuracy on the working of muscle sense.
In the estimation of the parents a distinct mark of progress is
registered the first time the baby follows a movement with its eyes. As
soon as it does this accurately, and also brings both eyes to bear on
any object, its muscle sense is known to be in efficient operation, so
far, at least, as the eye muscles are concerned. Equilibrium sense first
shows itself when real balancing motions of the body are made.
The senses of taste and smell may be operative to some degree in very
young children, but it is doubtful whether they have either the breadth
or the acuteness that will be shown later in life. Recognition of
disagreeable tastes or smells seems to appear earlier than appreciation
of agreeable. This is in line with the general fact that the
self-protective reactions are developed very early.
Hearing and sight are probably in working order practically from birth.
It is customary to test the sight of the new-born by passing a light
directly in front of the eyes. If sight is present there will be some
appreciable eye movement, suggesting that the eyes are attempting to
follow the moving light. There is no reason to believe that there is any
such thing as definite looking at objects thus early. So long as the
eyes continue to roll aimlessly about, and before they begin to focus
accurately, they are more likely concerned with distinctions between
light and shadow, than with perceptions of form or size. In general we
may say of the senses that those concerned immediately with bodily
discomfort are about as fully developed at birth, or shortly thereafter,
as they ever will be, while those that have to do with the general
adjustments of the body to its environment reach full efficiency more
gradually.
The higher parts of the brain, especially those concerned on the one
hand with the mental life (the cerebrum), and on the other with the
complicated reflex acts involved in locomotion (the cerebellum), are not
ready to begin active functioning when the child is born. Indeed some
parts of the cerebellum do not take on final form for from eight months
to two years afterward. It is thought by some that the question of
whether a child will learn to walk early or late depends, in part at
least, on how soon his cerebellum reaches complete development.
Most parents are fully alive to the importance of abundant warm covering
when their children are to be taken out into the cold, but there is much
less appreciation of the harm that may be done by too much clothing in
extremely hot weather. Of special importance is the avoidance of
exposure to sharp drops in temperature. The adult adjusts himself more
or less automatically to these, whereas the infant does so to only a
limited extent.
Finally, the hold of the infant upon life, that quality that we know as
ruggedness or vitality, is much slighter than it will be after a few
years. Not only is the susceptibility to many kinds of infectious
diseases very much greater, and the power of resisting them very much
less, but the ill effects of poisons, whether taken in with the food or
breathed in with the air, are more pronounced. Thus the vitiated air of
slum dwellings, saturated with the effluvium from unwashed bodies and
unclean clothing, while trying enough for the average grown person, is
deadly for all but the toughest babies. Even in the ordinarily well-kept
home, especially in the winter time when ventilation is apt to be
neglected, the air within the house tends to become unsatisfactory from
the standpoint of the infant’s welfare.
The wise parent, and wise he must be at this time, relaxes his care in
just proportion as the child achieves ability to do things for himself.
Since bodily development is more rapid than mental the close supervision
of food, clothing, and physical occupation is necessary only during the
early years, but the task of building up, through the slow processes of
education, the sort of mind which will be able to do its proper share in
dealing with the difficulties which confront the coming generations is
one to which may well be devoted the best thought and effort not only of
the parents, but of organized society as a whole.
Typographical errors corrected by the etext transcriber:
that their less curvaturos=> that their less curvatures {pg 114}
as fast as it it formed.=> as fast as it is formed. {pg 180}
Russian invesigator showed=> Russian investigator showed {pg 240}
quantities of axygen=> quantities of oxygen {pg 254}
unless artificial air can be procured=> unless artificial aid can be
procured {pg 303}