SECT. LXXVIII.—ON GOUT AND ARTHRITIS.

It is not weakness of the parts alone that occasions gouty and arthritic

complaints; for then the paroxysms would be without ceasing, inasmuch as

the debility is always present in the weak parts. Neither is a humour the

sole cause, for then the complaint had not attacked the joints only. But

the disease is occasioned by a preternatural humour and a weakness of the

parts meeting together. For when the nutritive power of the parts becomes

debilitated from repletion with food inducing dyspepsia, the prevailing

humour, fixing in some of the joints which are already in a weak state,

and stretching the nervous ligaments, produces pain. For the inflammation

is not an original affection of the nerves of volition; as then it would

have affected also the parts between the joints, such as the middle of

the legs, thighs, arms, and forearms; but those of volition are affected

sympathetically. When, therefore, the humour is seated in the joints of

the feet only, the complaint is called podagra; but when the cause is

diffused over all the joints of the body, we commonly call it arthritis,

in which the vertebræ, scapulæ, jaws, and every other joint are attacked

with the disease. In certain cases the ears, teeth, and pharynx, and

sometimes even the liver and spleen participate in the arthritic pains,

when, if there is not a speedy translation of the disease to the joints,

the patients will be in urgent danger. The prevailing humour is sometimes

bilious, sometimes sanguineous, sometimes melancholic, but for the most

part it is pituitous and crude, being engendered by excess of food,

indigestion, and want of exercise. When the disease is protracted in

the joints, the humours become thick and viscid, so as to form what are

called tophi or chalk-stones. Sometimes the humour is of a compound

nature, so that the disease is difficult to distinguish, and difficult

to cure, or nearly incurable. The precursory causes of this affection

for the most part are immoderate labour, violent walking, frequent

exercise on horseback, the unseasonable use of venery, cold drink taken

unseasonably, eating of much cold or unwholesome food, and drinking much

wine. And some from accidents, as a blow, a sprain, or the like, have

experienced the first attack of this complaint, the materials of the

disease having previously remained quiet in the system until roused by

the proximate cause. Sorrow, care, watchfulness, and the other passions

of the mind, not only excite an attack of the disorder, but also generate

a cacochymy either primarily or incidentally. Wherefore the causes of

the complaint, as I have said, are various; but the differences of the

noxious humours are in so far easily detected, being discovered by their

colour and other symptoms. A bilious rheum, in addition to paleness and

redness of colour, occasions a sensation of heat and acute pain, and is

speedily determined to the skin, nor is it attended with much swelling.

It is exacerbated by heating applications, and relieved again by cooling,

which, for the most part, is the case with all the others, but more

particularly when the exciting cause is bilious. Fever also frequently

comes on at the height of the paroxysms, and then they are thirsty. Thus

also you will find the skin darker when from a melancholic humour; white

and watery when from a pituitous, in which case the pain is more latent

and more slowly occasions swelling; and the colour is sanguineous when a

bloody humour prevails. In order to form a more decided diagnosis, you

will be assisted by taking into account the previous mode of life, and so

forth.

_The cure of rheums from a bilious humour._ The commencement of the cure,

when from yellow bile, more especially if the quality of it occasion the

disorder, should be the evacuation of the offending humour by purgative

medicines, such as that from rhodomel, that from quinces, the antidote

called picra, and aloetic pills. During the paroxysms, we may apply

externally rose-oil with the yelk of an egg, and some wine, rubbing

the part gently with it; and apply the herbs of a cold nature, such as

nightshade, purslain, henbane, houseleek, marsh-lentil, endive, poppy,

knotgrass, rose-leaves, and the like. These things may be sometimes

rubbed in, and sometimes applied in the form of a cataplasm, with crumbs

of bread soaked in oxycrate, or from barley-meal with rose-oil. When the

inflammation of the joints is of an erysipelatous nature, a decidedly

paregoric application is the peel of a fresh gourd laid on the part, or

the fleshy part of a pompion or cucumber, both alone and with bread; or

the leaves of perdicium (_pellitory of the wall?_), and ivy with bread

and fine polenta. And fleawort boiled in barley-flour mitigates the

inflammatory heat in a wonderful manner; and so also the rose-cerate

cooled with some of the frigorific juices, and that prepared from the

flour of beans. It is prepared thus: Of wax, oz. v; of chamomile-oil, oz.

iiss; of rose-oil, oz. iiss; of the flour of beans, oz. ss; the yelks

of five eggs.—_Another_, a cataplasm: Pound green mallows boiled; and

having made fleawort to the consistence of bird-lime separately, mix

together; then add the red part of eggs and chamomile-oil, and apply as

a cataplasm. When the pain is great and difficult to endure, we must

have recourse to preparations of saffron, of horned poppy, and of opium,

triturating them with oxycrate, and then using them in the form of

liniments, or of cataplasms with crumbs of bread. Galen makes mention of

this one: Of poppy-juice (_opium_), dr. iv; of saffron, dr. j; triturate

with milk of a cow or of a goat; or add the inner part of bread, and

having softened it by touching it with a little rose-oil, use for a

cataplasm. Or triturate the opium and saffron with the milk, and add to

the rose-cerate. And the cerate made from the torpedo and the oil of the

same are possessed of similar properties.—And this one in like manner:

Of crumbs of bread soaked in water or in oxycrate, and of houseleek, or

of nightshade, or of purslain, and of the fleshy parts of dates, and

of poppy-seeds, equal parts; of roasted yelks of eggs and rose-oil, q.

s.; form a cataplasm. The use of narcotics must not be continued, but

until the violence of the pain be abated; for the frequent use of them

occasions impaction and tophi, and makes the difficulty of motion to

be protracted. After the use of anodynes, then, we must have recourse

either to diachylon dissolved in oil of chamomile, or the composition

from marshmallows, or some such application. After we have warmed the

congealed parts, we must strengthen them by a plaster of dates dissolved

in vinegar and rose-oil or wine and rose-oil. Or, if the weight of the

plasters prove troublesome, we may rub in the juice of acacia with

oxycrate, or lycium along with saffron, horned poppy, and the juice of

perdicias in oxycrate. The diet should be cooling and moistening, such as

ptisans, and spoon-meats from chondrus, and of pot-herbs, the mallows,

the lettuce, and the endive; and of birds, more especially the young of

domestic fowls; and of fishes, those caught in rocky places, and the

sea-urchin, shell-fish, and the like. Let them avoid all things that are

heating and form pale and yellow bile, old wines both the yellow and

dark, and repletion. Let them use baths of sweet water, even at the time

of the defluxions, as far as regards the cause of them, unless something

else prohibit. Let them avoid violent passion, abstinence, acrid food,

drinking of wine, immoderate labour, and venery.

_The cure of rheums from a sanguineous humour._ In those cases in

which the prevailing humour is sanguineous, we must have recourse to

venesection without delay, and also in cases where the prevailing humour

is phlegm or black bile; since in them the humour is for the most part

contained in the veins, proving injurious by its quantity rather than

its quality. We must have recourse then to venesection only at the first

attack of the disease; since those who have had already frequent attacks

of rheumatism are injured rather than benefited by the loss of blood,

more especially when the body is naturally cold or weak. After the

evacuation of the blood, if there was more than a plethora of blood, we

must have recourse to purging with hiera after a short interval. And the

Julian oxymel is a purgative suitable to these cases. Those who reject

such purgative medicines may use these pills: Of aloes, of colocynth,

of black hellebore, of scammony, of each, oz. j; of euphorbium, oz. ss;

of nitre, oz. ss; mix with the juice of cabbage, and give according to

the patient’s strength. It will be better, however, if prepared with the

juice of quinces.—Another pill given to gouty persons in the paroxysms,

during the remission, and from whatever humour: Of aloes, oz. vj; of

agaric, oz. ss; of saffron, oz. ss; of costus, oz. j; of spikenard,

oz. j; of schenanth, oz. j; of balsam fruit, oz. j; of cassia, oz. ij;

of scammony, oz. ij; of dodder of thyme, oz. iiiss. A moderate dose is

scr. ij; and a full one, scr. iv. Pills of Armenian stone also purge

in a wonderful manner, being particularly applicable in arthritic

cases, whether given at the commencement, in the decline, or during the

remissions of defluxion. And since some avoid scammony because it is bad

for the stomach, we may give them these things when a pituitous matter

prevails: Of the medullary part of colocynth, of black hellebore, of

bdellium, of gum, of aloes, of each, oz. j; of Alexandrian nitre, of

euphorbium, of each, oz. ss. The dose is scr. iv. Instead of the gum I

have substituted dodder of thyme. Some, in the paroxysms of all arthritic

diseases, have recourse to purging with hermodactylus; but it is to be

remarked that the hermodactylus is bad for the stomach, producing nausea

and anorexia, and ought, therefore, to be used only in the case of those

who are pressed by urgent business; for it removes rheumatism speedily,

and after two days at most, so that they are enabled to resume their

accustomed employment. I knew a person who did not give the substance

of hermodactylus, nor any of the compound medicines containing it; but

boiling the plant itself with some of the common remedies, such as anise

or parsley, he gave the decoction to drink; and it was wonderful how

those who got it, after having evacuations of the bowels, were freed from

the rheumatism. It is necessary, however, as I said, because the medicine

is bad for the stomach, to correct the mouth of the stomach afterwards

by stomachics and tonics, along with things that are moderately heating.

Alexander says that purging by coronopodium is preferable to that by

hermodactylus, as it procures evacuation and relief from pain, and at

the same time is not bad for the stomach. But topical applications are

to be had recourse to in cases of pituitous rheumatism. When the pain

is moderate, a green cabbage-leaf may be applied, and also parsley,

fleabane, and the straight vervain; but when the pain is violent, take

of the flour of fenugreek, p. iij; of the flour of darnel, p. j; of the

flour of chick-peas, p. j; make a cataplasm with honied water, or thin

wine, with a little oil of privet, or of nard, more especially if in

winter. And the ashes of burnt cabbage-roots, or of their stalks, when

formed into a cataplasm with axunge, have proved beneficial to many; but,

in order that it may prove soothing, the axunge must be fresh, whereas,

if we wish it to be discutient, it must be old and salted. And in like

manner the dung of oxen, when boiled in honied water with barley-meal,

or fresh moist dung applied with the leaves of cabbage; and so also

goats’ dung by themselves, or boiled with barley-flour in oxycrate. And

since some have derived relief from seemingly opposite remedies (for a

mixture of various humours confounds the diagnosis), we must state the

materials thereof promiscuously. Wherefore the wild and garden orach in

a cataplasm with bread are beneficial, or the leaves of petty mullein,

triturated with bulbi and bread, or with polenta, or the cataplasm of raw

barley-meal. Upon the whole, when the cause of the complaint is obscure,

we must change sometimes to medicines of the same class, and sometimes to

the opposite, not continuing long with the same application when it does

not afford relief. These things we see every day occur in professional

matters. And often a certain remedy proves beneficial to one joint,

while another joint of the same patient similarly inflamed is not only

not benefited at the same time, but occasionally is even injured by it.

And this is a wonderful circumstance, that one and the same joint, when

treated with the same remedy, is sometimes benefited, and soon afterwards

exasperated. When a viscid and thick matter prevails, it is not perhaps

relieved by calefacients, but the acrid and hot quality of the humour

prevailing is to be soothed by frigorific remedies; nor is it at all

wonderful that a matter naturally cold, in the time of the inflammation,

should become heated and glowing, to say nothing of the admixture perhaps

of bile. The flour of lupines with oxymel or oxycrate, or the root of

laserwort, or of bryony, with bread, prevent the formation of tophi. And

the following composition is safely soothing and moderately discutient:

Of lycium, oz. j; of ammoniac perfume, oz. j; having triturated with very

old wine and oil of unripe olives, boil, and add of the flour of beans,

q. s.; and having boiled moderately, apply as a cataplasm. After the acme

of the complaint, if a swelling be left, apply a cataplasm with the bulbi

by themselves, or with fine polenta, until it produce excoriation; for in

this manner they act. When not relieved by the cataplasms, we may have

recourse to embrocations and affusions on the parts (more particularly

if the extremities be affected), with chamomile, melilot, or centaury

in decoctions. The preparation of capers has entirely relieved some.

The following is the most active of all the applications: Having boiled

thyme, marjoram, savory, and calamint in the most acrid vinegar, bathe

the parts affected with the vinegar, not only once, but often in a day,

with confidence. This has relieved many when suffering not only from

phlegm but also from bile.

Some observe this practice also: The acorns of the ilex being powdered,

are pounded and much boiled, and the joints of the extremities at the

commencement of the rheumatism are fomented for a considerable time with

the decoction, but it is poured from a sponge upon the inner parts;

whereby the violence of the offending matter is repelled. It also is

applicable to bilious cases; and, in like manner, immersion in hot

water without any decoction. For pains occasioned by intense cold, or

infarction of the joints, this is a powerful remedy: Of old oil, lb. iss;

of Alexandrian nitre, lb. j; of turpentine, lb. j; of euphorbium, oz.

j; of iris, oz. ij; of the flour of fenugreek, a sextarius and a half.

In these cases the remedies recommended for ischiatics are excellently

applicable. Many, in the case of those who are thus affected from a cold

cause, apply, after the acme, mustard with dried figs and the other

rubefacients, but some the preparation from cantharides. But these things

prove injurious afterwards, unless one use the emollient applications,

such as that from fuller’s herb, the one called Pyxis, that of Basilius,

that from the fir-tree, that from the poplar, those called Promium and

Lysiponium, and the stronger of the Acopa: in which cases sympathetic

affections of the nerves and impaction of the humours particularly take

place. And the application from the urine of a mule, more particularly

if applied at the acme, is beneficial in the cold rheums: and, in

like manner, the trochisk from the two hellebores is applicable for

the œdematous and spongy swellings; also fomentation with the toasted

salts; or otherwise affusion or embrocation with hot sea water; and the

plasters prepared from salts, those from strained lye and nitre, and the

cataplasms of a like nature after the acme. Food of a drier nature, and

not excrementitious, suits well with these; also abstinence from food,

or a spare diet, and refraining from frequent baths. Having bathed, they

should be rubbed with nitre and the other unguents used for friction.

In the decline, they should have recourse in particular to gymnastic

exercises and friction of the joints, and the natural baths, or the sand

baths, and emetics from radishes and food from grain. Those properly

prepared for it may be vomited or purged with the white hellebore.

_On rheums from a mixture of humours._ Those labouring under a mixture

of humours, after the evacuation of the blood at the commencement of the

disease, should use the topical remedies already mentioned. When the

sanguineous plethora is of a more bilious and acrid nature, recourse

may be had to those things recommended for bile; when it is of a colder

and more pituitous or melancholic nature, those afterwards mentioned,

with the exception of such as are very acrid; and if protracted, these

also may be used. And this cataplasm is applicable at the commencement:

Pomegranate rind, sumach, and polenta triturated with wine, are

applied in the form of a poultice.—_Another_: Having boiled the leaves

of cabbage, and triturated carefully, add the lees of vinegar, two

yelks of raw eggs and a little rose-oil, and having triturated, apply,

changing it frequently. Let them take food that is attenuant and of

little nourishment. Let them, therefore, abstain altogether from flesh

and pulse, from much wine of a dark colour; and, if possible, let them

abstain from drinking wine altogether. For I have known many persons

who have abstained altogether from this article alone, and all of them

derived benefit. Those who did so in the commencement of the complaint

were entirely freed from it; and those who were later in doing so

experienced afterwards fewer paroxysms, and these not of great severity.

If, therefore, no inconvenience occur, or be dreaded from it, they should

abstain from wine all their life. Those who from weakness or coldness

of constitution appear to sink under this regimen, after abstaining

from wine for two years, may gradually accustom themselves to take a

small quantity of diluted wine. Those who refrain from wine should take

instead of it a decoction of anise, or of some such seeds, avoiding

altogether the use of the autumnal fruits, and other things of a cold

nature, and also venery. Of those who attempt to get rid of the complaint

by continuing under a course of medicines for a complete year, many who

suffer from pituitous and redundant humours have been benefited thereby,

whereas such as are of a hot and dry intemperament have brought on sudden

death, the offending matter being translated to the intestines, kidneys,

side, lungs, or some vital part. It is better, therefore, for those who

are bilious and sanguineous, to abstain from wine; as from this course

there is no risk of falling into the dangers just mentioned. Those who

are affected with cold and redundant humours should take the theriac

of vipers more frequently if they have good digestion in winter, but

more rarely in summer; for it either removes the complaint altogether

or renders it more moderate, and proves injurious to none of the

afore-mentioned parts. And since some persons compel us to administer the

medicines called Antidotes, you should be aware that the following are

all of the same kind, namely, that from water plantain, that of Agapetus,

those called Atacton and Octaidon, that of Proclus, that from water

germander, that from coral, and many others. The safest of them all, and

yet of approved efficacy, is the one from coral, which dissolves tophi

that are formed in the joints. The properties of all these things, the

manner of using them, and the precautions to be observed with regard to

them, you will find described in the Pharmaceutical part of this Work;

and also the composition of depilatories for arthritic complaints, and

the mode of applying them to these habits, I mean the pituitous. Some,

for the entire removal of the complaint, boil whole wolves in oil,

wherewith they cure arthritic cases; some throwing them in alive, and

others dead, into a large caldron. And in like manner they boil hyænas,

making a discutient oil from them; and then filling the cistern of the

bath with it, and putting the arthritic patients into it, they direct

them to remain in it for a considerable time. By these means it happens

that not only the swellings about the joints, but the whole body, is

evacuated.

_On tophi, or chalk-stones._ Since tophi are often formed in the

joints, sometimes owing to a thick and terrene humour seating in

the parts, and sometimes owing to the use of applications which are

immoderately discutient and desiccant without being emollient, it is

proper to know that the most suitable remedies are such as are at

the same time emollient and discutient. Wherefore, old suet, marrow,

ammoniac, bdellium, very old oil, and storax, are emollient; and nitre,

salts, strained lye, adarce, euphorbium, and the like, are discutient

and desiccative. This is an excellent application for tophi in the

joints: Very old and acrid cheese pounded and applied with a decoction

of fat swines’ flesh, it also being old. For the chalk-stone breaking

spontaneously, a discharge of it takes place every day. The composition

from ham (which is prepared in two ways) is also an approved remedy, and

those described from strained lixivial ashes (potash?). And this one is

particularly excellent: Of aphronitrum, of turpentine, of protostacton,

of virgin wax (i.e. _bee-glue_), of each, oz. iv; of wax, oz. ix; of

colophonian rosin, lb. j; of oil, oz. xvj; mix together, and use for

chalk-stones and apostemes. The composition from dragon’s blood is of

wonderful efficacy for chalk-stones and many other complaints, but is

difficult to procure. But that from walnuts is not only efficacious but

at the same time easily procured; and is applicable not only to those who

are strong, but also to those who are sensitive, if mixed with honey or

the composition from anemone, in the proportion of two parts to one of

the composition. When these things are not at hand, an equal proportion

of ceruse may often be mixed with it.—_Another for tophi_: Having

triturated red arsenic, mix with mistletoe of the oak, and use.—_Another,

which is applicable also for fistula and ægilops_: Of oil, one sextarius;

of litharge, oz. viiiss; of arsenic, oz. j; boil the litharge and the oil

until they do not stain, then sprinkle the arsenic well levigated, and

before it catch fire, take off and use. The compositions from the flower

of Assian stone, when used during the intervals, are applicable to all

the collections which form in the joints; and some of the ancients attest

that they remove the complaint entirely. The composition from the flower

of salt, when applied in like manner during the remissions, is believed

to dissipate whatever swellings remain.

_On the prophylaxis of gout._ Gout and rheumatism, when formed, are

among the most difficult of diseases to cure, except by the methods we

have described; but, before being fixed, it is easy to prevent their

occurrence by restricting the diet, giving only such food as is of easy

distribution and not excrementitious, with a moderate allowance of

wine, and increasing the exercise as far as proper. As a remedy, salts

triturated with oil and rubbed into the joints, are of great use to all

who are anxious to avoid falling into a gouty affection, unless they

be of a dry intemperament. They ought to use it morning and evening

through life, and the same thing is to be used after the decline of the

inflammation.

* * * * *

COMMENTARY. Consult Hippocrates (Aphor. vi; Prognost. 15); Galen

(Comment. in Aphor. Hippoc., de Med. sec. loc. ix); Celsus (iv, 24);

Serenus Samonicus; Aretæus (Morb. Chron. ii, 12); Scribonius Largus

(41); Cælius Aurelianus (Tard. Pass. v, 2); Alexander (xi); Aëtius

(xii); Oribasius (Synops. ix, 58); Actuarius (Meth. Med. i, 21); Nonnus

(216); Marcellus (de Med. 35); Octavius Horatianus (ii, 21); Demetrius

Pepagomenos (de Podagra); Psellus (Opus Medicum); Macrobius (Saturnal.

vii, 4); Lucianus (Tragodopodagra); Serapion (iv, 25); Avenzoar (ii, 3,

28, ii, 7, 31); Avicenna (iii, 22, 2); Haly Abbas (Theor. ix, 41; Pract.

viii, 32); Alsaharavius (Pract. 38); Rhases (Divis. 102, ad Mansor. ix,

90, Libellus de Morb. Junct., and Contin. xxvi.)

The Prognostics of Hippocrates will be admitted at the present day to

be correct. Those who are old, or who have chalk-stones formed in their

joints, or lead a laborious course of life, or have dried bellies, cannot

be cured by any human means. Young persons not having _tophi_ formed

in their joints, and who live guardedly, and whose bowels will bear

the proper treatment, may be cured. These complaints are best removed

by dysenteries or other evacuations downwards. His principal remedies

are purgatives administered by the mouth or by injection, and local

applications of a cooling nature, and even pouring cold water on the

foot. When the pain of the gout becomes fixed in a joint, he directs us

to burn it with crude flax.

Seneca mentions it as a monstrous example of the depravity of his age,

that the women, by their luxurious habits, had become subject to gout.

(Epist. 95.)

According to Galen, gout and arthritic complaints are occasioned by

a collection of some humour in the affected part. This humour may be

blood, phlegm, or a mixture of phlegm and bile, or of blood along with

these, or simply a crudity. This crude humour, he remarks, sometimes

concretes into _tophi_. The first indication in attempting the cure is to

evacuate the offending humour by bleeding or purging; and then repellent

and discutient applications are to be used. He has given a great many

prescriptions for these. He disapproves of the warm bath in rheumatic

attacks; for, he says, although it appears at first to give relief, it

ultimately aggravates the complaint. (Therap. ad Glauc. ii.)

For an able and full explication of the ancient theory of the humours,

and the manner in which they give rise to arthritic complaints, we refer

the reader to Macrobius (l. c.)

Unfortunately the chapter of Aretæus on the treatment of arthritic

complaints has come down to us in a mutilated state. It appears however,

that he trusted to hellebore as the great remedy in such cases. His local

applications are wool dipped in rose-oil and wine; a sponge soaked in

oxycrate, or such like cataplasms. When the disease is hereditary, he

says it is generally incurable.

Celsus recommends various refrigerant and anodyne applications to the

affected part, such as a sponge soaked in cold water, or in oil and

vinegar, or the same soaked in hot water having poppies boiled in it,

or a mixture of pitch, wax, and alum. The other points of his practice

deserve attention, but we shall not enter upon them, as we wish to afford

room for a fuller abstract of the doctrines of Alexander.

Gout, according to Psellus, is occasioned by an atony of the nutritive

faculty, whereby a thick humour is collected in the system.

Scribonius Largus recommends his favorite remedy for local pains, namely,

the application of a living torpedo to the part affected.

Alexander begins with noticing the common opinion that gout is

irremediable by the art of medicine, which he affirms not to be the case

provided proper attention be paid to the different varieties of it. There

are, he says, many causes of the disease; for sometimes a hot blood flows

into the cavity of the joint and occasions violent pains; and, in like

manner, a defluxion of bile getting between the tendons and ligaments

occasions pain by burning and stretching the parts: phlegm likewise,

by producing cold and compression, becomes the cause of violent pains;

and in like manner the melancholic humour, not only by its coldness and

pressure but also by occasioning a sense of heaviness, brings on no

ordinary paroxysms. Sometimes a simple quality of the humours, such as

heat, cold, dryness, or humidity, will cause a defluxion. The prevalence

of a bilious humour is ascertained by the absence of swelling; from the

pain being rather a fiery heat than distension; and from the colour being

red. The proper remedies in this case are cholagogues, which must not be

of a heating nature nor offensive to the stomach; for when the stomach

is deranged the nerves sympathise and rheumatism is the consequence.

He gives prescriptions for a variety of such compositions containing

scammony, agaric, and the like, mixed with pepper, &c. He particularly

commends pills of scammony and wormwood. He also recommends cooling and

anodyne applications to the affected parts, such as rose-oil with the

yelk of an egg, and the like. He enjoins particular attention to the

diet, in order to avoid such things as have a tendency to form bile.

He recommends moderate exercise rather before than after a meal, but

forbids to carry it to excess. He speaks favorably of baths of common

water. He concludes this part with minute directions about the local

applications: but, as we have already stated his principles, we shall

not enter upon the detail of his practice. When gout is occasioned by

phlegm the part is neither hot nor red; is benefited by calefacients and

injured by refrigerants. For this variety he recommends particularly a

combination of purgative and attenuant medicines, such as the Julian

oxymel, which contained white hellebore, agaric, polypody, thyme, cumin,

&c. After purging he greatly commends hot and attenuant medicines, in

particular the composition from coral, which, among other ingredients,

contained birthwort, spikenard, cloves, myrrh, &c. (Birthwort formed

one of the principal ingredients of the celebrated Portland powder.) He

describes various other antidotes containing bitters, attenuants, and

calefacients. His local applications in this case are pounded cabbage,

parsley-seed, or fleabane, if the pain is moderate; but otherwise he

recommends anodyne cataplasms. Should these, however, rather produce

an increase of the pain, he directs us to substitute instead of them

discutient and repellent applications, such as decoctions of thyme,

mint, &c. with vinegar. He also recommends various cerates with the same

intention. Some, he says, have been benefited by stronger applications,

such as blisters of cantharides, sinapisms, or the like; but he does

not approve of the barbarous practice of burning with the substances

called _iscæ_ (see Aëtius and Paulus), nor of the above-mentioned

rubefacients, but prefers a combination of emollients with discutients.

When it is suspected that the gout proceeds from an overflow of blood

upon the joint, he recommends us to have recourse to bloodletting, unless

otherwise contra-indicated. He proscribes such articles of food as

engender much blood, as all sorts of flesh, especially pork; also sweet

wines and intemperance of every kind. He says he has known some cured by

simply refraining from wine. He then gives directions for the formation

of several topical applications which are of a repellent and discutient

nature. He speaks very favorably of a sponge soaked in an astringent

wine or oxycrate. He then gives ample directions for discussing Tophi or

chalk-stones. He lays it down as a general rule that such applications

should contain ingredients of a moderately calefacient, discutient, and

solvent nature. Among the articles which enter into these compositions we

remark litharge, old oil, sanguis draconis, nitre, turpentine, ammoniac,

&c. He then states, that as some do not choose to submit patiently to

the methodical plan of treatment, but insist upon getting medicines

to allay at once the violence of the pains, he, although he did not in

general approve of this practice, would now give an account of such

remedies. For this purpose, he says, _hermodactylus_ is particularly

trusted to by some; and he admits that it seldom fails to remove a

paroxysm, but affirms that it occasions more frequent returns of it.

Some, he adds, have endeavoured to correct its prejudicial effects by

adding to it cumin, mastich, or ginger, thinking that its action is

narcotic; but this he affirms to be a mistake, for in that case it could

not prove cathartic. He admits, however, that these things may prove

useful by correcting its bad effects upon the stomach. He then gives

various receipts for mixtures containing hermodactylus. As a specimen

of them we may mention the first, which consists of hermodactylus,

myrrh, pepper, and anise, to which scammony may be added. He recommends

it, however, in general, to be given in the form of pills with aloes,

scammony, elaterium, and colocynth. But, as mentioned by our author,

instead of it he prefers the coronopodium. It is the same, we presume,

as the coronopus of Dioscorides, or our buckthorn plantain (_plantago

coronopus_ L.), although the commentators are not agreed upon this point.

(See Matthiolus.) Gesner supposes it a species of _ranunculus_, which he

calls _polyanthemon_. Alexander then gives directions for various local

applications of an anodyne nature, containing opium, strychnos, ceruse,

wax, &c. We regret to say that so admirable a treatise should conclude

with some frivolous directions for curing the disease by means of amulets

of approved efficacy! However, the advocates of the Mesmerian system of

animal magnetism do not hesitate to admit their remedial powers. On the

periapta or amulets of the ancients, see Andreas Laurentius (de Marab.

Strum. Sanat, 85.)

Our limits will not permit us to do justice to the account of the

gout given by Aëtius. Like Aretæus, he maintains that the disease is

hereditary. His general views of the nature of the complaint and his

treatment are very plausible. He says it is occasioned by weakness

of the part and a redundance of humours; that the proper treatment

therefore consists in evacuating the humours by bleeding and purging, and

afterwards in strengthening the part.

Cælius Aurelianus considers arthritis, podagra, and chiragra, as diseases

of the same genus. The usual precursory causes are intemperance,

indigestion, debauchery, cold, too much or too little exercise, and

external injuries. Some, he adds, are of opinion that it is transmitted

from father to son. He gives the symptoms of these complaints with his

wonted accuracy. They are seated for the most part, he says, in the

nerves, by which term he probably means the tendons and membranes. He

remarks the well-known propensity which persons attacked with gout have

to attribute the swelling and pain to a sprain or some such accident.

If the belly be constipated, he advises us to open it by a simple

clyster. He recommends us to abstract blood from the affected part by

scarifications, which, he says, will occasion less irritation than

cupping or leeching. Sponges squeezed out of hot water, or oil and water,

or the decoction of fenugreek, are then to be applied to the part; for he

thinks these preferable to a cataplasm, as it is often too heavy. When

on the decline, he approves of bathing, spare diet, emollient ointments,

and gentle exercise, beginning with gestation, and proceeding to the

stronger kinds of it. When they can be borne, he approves of stimulant

applications, such as dropaces, heated sand, and even sinapisms. He also

speaks favorably of vomiting produced by radishes, hellebore, hip-baths

of oil, fomentations with hot salt water, and swimming in hot water or

even in cold. He particularly commends the naturally-medicated waters, or

spas (as they are now called), such as those of Albula or Cutilia, which,

he says, will either cure or mitigate the complaint. He disapproves of

burning the joints (the reader will have remarked his general aversion

to the cautery), and the indiscriminate application of various narcotics

and other such things. He also condemns the free use of emetics, (which,

he says, prove injurious to the stomach, and occasion a determination

to the head,) of purgatives, acrid clysters, and diuretics. In short,

his practice is not unlike that of our Sydenham. His grand rule is to

keep upon a spare diet, or even to maintain complete abstinence at the

commencement. The formula for his diacentaureo (as Van Swieten remarks)

is the same as that for the Portland powder, namely, Aristoloch. rotundæ;

gentianæ; sum. chamædryos; centaur. min. p. æquales. Cælius Aurelianus,

Galen, Aëtius, Celsus, Aretæus, Oribasius, Scribonius, and Horatianus

make no mention of the hermodactylus. Myrepsus and Actuarius make mention

of a hermodactylus, but Matthiolus and the commentator on the former

think theirs a different plant from the hermodactylus of the other Greek

authors. This may be true, and yet the microscopic eye of critics often

fancies it can see differences which other people are puzzled to remark.

We may mention further regarding the practice of Cælius Aurelianus, that

he speaks of soothing the pains of rheumatism, more especially of the

hip-joint, by music. On this practice see also Aulus Gellius (iv, 13);

Athenæus (Deipnos. xiv, 18); Apollonius (Hist. Marab.); Pliny (H. N.

xxviii, 2.)

There is nothing very important in Nonnus, Octavius Horatianus, or

Oribasius. We shall now give a brief abstract of the curious treatise

on the gout by Demetrius Pepagomenos. The work is dedicated to the

Emperor Michael Paleologus, who flourished about the year 1260; and it

was published by Morel at Paris, A.D. 1558. The author commences by

explaining the nature of that derangement of the animal economy which

occasions this complaint. This he does at considerable length, but in

much the same terms as Macrobius, to whom the reader has been already

referred for an exposition of the humoral pathology. His physiological

opinions appear to us to be highly ingenious and philosophical. He comes

to the conclusion that gout is occasioned by a collection of humours

in the affected joint, these humours being the product of imperfect

digestion and of the retention of excrementitious superfluities, which

ought to have been evacuated from the system. He says the procatarctic or

remote causes of arthritic affections are, long-continued indigestion,

repletion with food, drinking too much wine, venery, unusual exercise,

indolence, and retention of the natural secretions. Venery, in

particular, is said to weaken the tone of the nervous parts. He then

proceeds to explain that when crudities are formed in the system, those

parts which are strong and vigorous cast them off, which those that are

weak cannot effect, and hence collections of such humours take place

in them. The prophylaxis of the complaint, he remarks, is easily laid

down, but is difficult to follow, namely, to observe great moderation in

eating and drinking, and to avoid indigestion. His grand principle of

practice is evacuation, which, according to the general rule laid down

by Hippocrates, is the proper remedy for repletion. He then shows that

vomiting is the mode of evacuation most applicable in this complaint,

because it empties the stomach, which is the fountain whence the

humours are derived. His comparison of the stomach to a fountain which

irrigates all parts of the system is very appropriate, and is beautifully

illustrated by him. He recommends, however, vomiting by simple means; and

for this purpose directs the patient to swallow meat imperfectly chewed,

radishes, leeks, &c. and, having drunk some honied water, to excite

vomiting by tickling the throat with a feather or the finger. He forbids

the use of strong emetics. His second method of evacuation is by purging,

which he recommends to be done by pills containing aloes, hermodactylus,

cinnamon, and scammony. He then proceeds to the cure when an attack has

come on. In this case, he recommends us to begin with letting blood,

unless the stomach be loaded with impurities, when an emetic must be

premised, lest the emptiness of the veins produced by venesection should

cause these crude humours to be conveyed over the body. Venesection,

he remarks, is particularly applicable at the commencement, when there

is simply a plethora of blood, but it is rather prejudicial afterwards

when the fluids become altered in quality. In such cases, as he fully

explains, purging is the proper remedy, especially when performed by

hermodactylus, which, he says, he had found from experience to answer

well, from whatever cause the disease had originated. He directs it to

be combined with various calefacients and aromatics, such as birthwort,

cinnamon, and pellitory. He then makes an ingenious reply to those who

affirmed that the disease is not to be cured by purgatives, but that it

is sometimes exacerbated by them. In such cases, he properly remarks, it

is not the remedy that is in fault but the misapplication of it. Those

who cannot bear cathartics by the mouth may have clysters given them;

or the preparations from elaterium, juice of sow-bread, or the like,

may be applied to the navel. He afterwards gives directions about the

local applications, which are nearly the same as those recommended by

Alexander. We will have occasion, in the Seventh Book, to discuss the

question respecting the nature of the ancient hermodactylus; and we

shall merely state here our own decided persuasion that it was a species

of colchicum or meadow-saffron. It forms one of the ingredients of the

celebrated _Eau médicinale d’Husson_. From the effects produced by the

_Eau médicinale_ we are inclined to think, however, that a certain

proportion of hellebore must have entered into its composition, as we

have never found the colchicum to act so violently as the _eau_ is said

to do. We have stated above that Cælius Aurelianus makes no mention of

the hermodactylus. However, the great modern advocate for Methodism,

Prosper Alpinus, speaks favorably of it, and says decidedly that it is

the colchicum of the Greeks. It appears not to have fallen into disuse in

his time. (De Med. Meth. ix, 4.)

The Arabians follow the Greeks closely in the general principles of

treatment, only substituting certain articles introduced into the Materia

Medica by themselves. Thus Serapion strongly recommends purging with

myrobalans, prunes, and tamarinds. He, Avicenna, and Rhases, join in

praising the virtues of the hermodactylus. Their local applications are

similar to those of the Greeks. When the pain is violent, Serapion even

approves of pouring cold water upon the affected part. Rhases approves

of burning the joint in certain cases. Avicenna directs us to cover the

part with oil and salt, and thus to apply the cautery gradually. Avicenna

speaks more favorably of bathing in thermal waters than any of the other

authorities. According to Haly Abbas, arthritic diseases are collections

of superfluities of the system in some joint which is labouring under

debility. These superfluities are said to be produced by repletion and

indigestion. The debility is generally occasioned by immoderate exercise,

intemperance, debauchery, or some such cause; and a joint having become

weakened, all the impurities of the system are collected into it. He

says that young persons and women who menstruate regularly are scarcely

liable to the gout. He agrees with the authorities already mentioned in

holding it to be hereditary. When the humour in the joints concretes into

chalk-stones, he pronounces the case to be incurable. When the disease

is produced by a sanguineous plethora, he recommends us to begin with

bleeding, and then to use cooling lotions, or even to pour cold water on

the joint. When these do not succeed, anodyne applications, containing

opium, mandragora, lettuce, saffron, and the like, are to be used.

When the pain has abated, any swelling which remains may be discussed

by applying to the part a decoction of marjoram, melilot, chamomile,

and the like. When the defluxion is connected with bile, he recommends

first emetics, and then drastic purgatives, such as aloes, scammony,

colocynth, and hermodactylus. But, if the patient’s stomach be weak,

he recommends milder laxatives. When the defluxion is of a phlegmatic,

that is to say, of a serous nature, he directs us to give the active

cathartics already mentioned, especially hermodactylus; and, if it be

the summer season, he advises us also to give emetics. He cautions us

against using local applications of too stimulant a nature at first,

lest they dispel the more fluid parts of the defluxion and leave the

grosser behind. This is but a meagre sketch of his interesting account of

arthritic diseases. Alsaharavius calls these complaints collections of

phlegm, bile, or blood. He holds that they are often hereditary. Like all

his countrymen, he approves of hermodactylus, which he gives in the form

of pills, with myrobalans, colocynth, turbit, castor, opopanax, &c. When

fulness of blood is present, he recommends bleeding.

The hermodactylus is recommended for the cure of arthritic diseases by

the earlier of the modern writers on medicine. See Lanfrancus (ii, 3.)

Among the ancient treatises on gout, we have mentioned the tragi-comic

poem entitled ‘Tragodopodagra,’ usually ascribed to the famous Lucian.

It ridicules, with much humour and severity, the many pretended nostrums

for this complaint. Among the remedial articles mentioned, we remark

hellebore, nitre (_soda_), henbane, poppy, fenugreek, and galls. The

ridicule thus bestowed upon the use of specifics for the cure of a

complaint so complicated as gout, is no doubt well founded; but we

ought not to be deterred, by the ill success of such a practice, from

attempting to afford relief upon general principles, as ably laid down

by Alexander, Demetrius, and Haly Abbas. We would fain impress upon the

physician and his patient, that more than is usually believed might be

accomplished in all arthritic diseases, by correcting the disorder of the

digestive functions by means of a suitable diet and regimen; and that it

is only when the constitution is radically unsound—when the joints are

deformed by concretions, and the vital powers have been worn out by a

long-continued course of debauchery—that we need adopt the discouraging

opinion of Ovid, as expressed in the following line:

“Tollere nodosam nescit medicina podagram.”

(Pont. i, el. 4.)

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