POISONOUS SERPENTS AND THEIR VENOM.

By Dr. G. ARCHIE STOCKWELL.

Chemistry has made astounding strides since the days of the sixteenth

century, when Italian malice and intrigue swayed all Europe, and

poisons and poisoners stalked forth unblushingly from cottage and

palace; when crowned and mitered heads, prelates, noblemen, beneficed

clergymen, courtiers, and burghers became Borgias and De Medicis in

hideous infamy in their greed for power and affluence; and when the

civilized world feared to retire to rest, partake of the daily repast,

inhale the odors of flower or perfume, light a wax taper, or even

approach the waters of the holy font. These horrors have been laid

bare, their cause and effect explained, and tests discovered whereby

they may be detected, providing the law with a shield that protects

even the humblest individual. Great as the science is, however, it is

yet far removed from perfection; and there are substances so

mysterious, subtle, and dangerous as to set the most delicate tests

and powerful lenses at naught, while carrying death most horrible in

their train; and chief of these are the products of Nature's

laboratory, that provides some sixty species of serpents with their

deadly venom, enabling them in spite of sluggish forms and retiring

habits to secure abundant prey and resent mischievous molestation. The

hideous _trigonocephalus_ has forced the introduction and acclimation

of the mongoose to the cane fields of the Western tropics; the tiger

snake (_Heplocephalus curtus_) is the terror of Australian plains; the

fer de lance (_Craspedocephalus lanceolatus_) renders the paradise of

Martinique almost uninhabitable; the tic paloonga (_Daboii russelli_)

is the scourge of Cinghalese coffee estates; the giant ehlouhlo of

Natal (unclassified) by its presence secures a forbidding waste for

miles about; the far famed cobra de capello (_Naja tripudians_)

ravages British India in a death ratio of one-seventh of one per cent.

of the dense population, annually, and is the more dangerous in that

an assumed sacred character secures it largely from molestation and

retributive justice; and in Europe and America we have vipers,

rattlesnakes, copperheads, and moccasins (_viperinæ_ and _crotalidæ_),

that if a less degree fatal, are still a source of dread and

annoyance. All these forms exhibit in general like ways and like

habits, and if the venom of all be not generically identical, the

physiological and toxicological phenomena arising therefrom render

them practically and specifically so. Indeed, their attributes appear

to be mere modifications arising from difference in age, size,

development, climate, latitude, seasons, and enforced habits, aided

perhaps by idiosyncrasies and the incidents and accidents of life.

In delicacy of organism and perfection in mechanism and precision, the

inoculatory apparatus of the venomous reptile excels the most

exquisite appliances devised by the surgical implement maker's art,

and it is doubtful whether it can ever be rivaled by the hand of man.

The mouth of the serpent is an object for the closest study,

presenting as it does a series of independent actions, whereby the

bones composing the upper jaw and palate are loosely articulated, or

rather attached, to one another by elastic and expansive ligaments,

whereby the aperture is made conformatory, or enlarged at will--any

one part being untrammeled and unimpeded in its action by its fellows.

The recurved, hook-like teeth are thus isolated in application, and

each venom fang independent of its rival when so desired, and it

becomes possible to reach points and recesses seemingly inaccessible.

The fangs proper, those formidable weapons whose threatening presence

quails the boldest opponent, inspires the fear of man, and puts to

flight the entire animal kingdom--lions, tigers, and leopards, all but

the restless and plucky mongoose--and whose slightest scratch is

attended with such dire results, are two in number, one in each upper

jaw, and placed anteriorly to all other teeth, which they exceed by

five or six times in point of size. Situated just within the lips,

recurved, slender, and exceeding in keenness even the finest of

cambric needles, they are penetrated in their longitudinal diameter by

a delicate, hair-like canal opening into a groove at the apex,

terminating on the anterior surface in an elongated fissure. As the

canal is straight, and the tooth falciform, a like groove or

longitudinal fissure is formed at the base, where it is inclosed by

the aperture of the duct that communicates with the poison apparatus.

At the base of each fang, and extending from a point just beneath the

nostril, backward two-thirds the distance to the commissure of the

mouth, is the poison gland, analogous to the salivary glands of man,

that secretes a pure, mucous saliva, and also a pale straw-colored,

half-oleaginous fluid, the venom proper. Within the gland, venom and

saliva are mingled in varying proportions coincidently with

circumstances; but the former slowly distills away and finds lodgment

in the central portion of the excretory duct, that along its middle is

dilated to form a bulb-like receptacle, and where only it may be

obtained in perfect purity.

When the reptile is passive, the fangs are arranged to lie backward

along the jaw, concealed by the membrane of the mouth, and thus offer

no impediment to deglutition. Close inspection, however, at once

reveals not only their presence, but also several rudimentary ones to

supply their place in case of injury or accident. The bulb of the

duct, too, is surrounded by a double aponeurotic capsule, of which the

outermost and strongest layer is in connection with a muscle by whose

action both duct and gland are compressed at will, conveying the

secretion into the basal aperture of the fang, at the same time

refilling the bulb.

When enraged and assuming the offensive and defensive, the reptile

draws the posterior portion of its body into a coil or spiral, whereby

the act of straightening, in which it hurls itself forward to nearly

its full length, lends force to the blow, and at the same instant the

fangs are erected, drawn forward in a reverse plane, permitting the

points to look outward beyond the lips. The action of the compressor

muscles is contemporaneous with the blow inflicted, the venom being

injected with considerable violence through the apical outlets of the

fangs, and into the bottom of the wound. If the object is not

attained, the venom may be thrown to considerable distances, falling

in drops; and Sir Arthur Cunynghame in a recent work on South Africa

relates that he was cautioned not to approach a huge cobra of six feet

or more in length in its death agony, lest it should hurl venom in his

eyes and create blindness; he afterward found that an officer of Her

Majesty's XV. Regiment had been thus injured at a distance of

_forty-five feet_, and did not recover his eyesight for more than a

week.[1]

[Footnote 1: Presumably the Natal ombozi, or spitting cobra, _Naja

hæmachites_, who is fully equal to the feat described.]

With the infliction of the stroke and expression of its venom, the

creature usually attempts to reverse its fangs in the wound, thereby

dragging through and lacerating the flesh; an ingenious bit of

devilishness hardly to be expected from so low a form of organism; but

its frequent neglect proves it by no means mechanical, and it

frequently occurs that the animal bitten drags the reptile after it a

short distance, or causes it to leave its fangs in the wound. Some

serpents also, as the fer de lance, black mamba, and water moccasin,

are apparently actuated by most vindictive motives, and coil

themselves about the part bitten, clinging with leech-like tenacity

and resisting all attempts at removal. Two gentlemen of San Antonio,

Texas,[2] who were bitten by rattlesnakes, subsequently asserted that

after having inflicted all possible injury, the reptiles scampered

away with unmistakable manifestations of pleasure. "Snakes," remarked

one of the victims, "usually glide smoothly away with the entire body

prone to the ground; but the fellow I encountered traveled off with an

up and down wave-like motion, as if thrilled with delight, and then,

getting under a large rock where he was safe from pursuit, he turned,

and raising his head aloft waved it to and fro, as if saying. 'Don't

you feel good now?' It would require but a brief stretch of the

imagination to constitute that serpent a veritable descendant of the

old Devil himself."

[Footnote 2: On the authority of N.A. Taylor and H.F. McDaniels.]

As the first blow commonly exhausts the receptacle of the duct, a

second (the venom being more or less mingled and diluted by the

salivary secretion) is comparatively less fatal in results; and each

successive repetition correspondingly inoffensive until finally

nothing but pure mucus is ejected. Nevertheless, when thoroughly

aroused, the reptile is enabled to constantly hurl a secretion, since

both rage and hunger swell the glands to enormous size, and stimulate

to extraordinary activity--a fortuitous circumstance to which many an

unfortunate is doubtless indebted for his life. The removal of a fang,

however, affects its gland to a degree that it becomes almost

inoperative, until such a time as a new tooth is grown, and again

calls it into action, which is commonly but a few weeks at most; and a

person purchasing a poisonous serpent under the supposition that it

has been rendered innocuous, will do well to keep watch of its mouth

lest he be some time taken unaware. It may be rendered permanently

harmless, however, by first removing the fang, and then cauterizing

the duct by means of a needle or wire, heated to redness; when for

experimental purposes the gland may be stimulated, and the virus drawn

off by means of a fine-pointed syringe.

In what the venom consists more than has already been described, we

are not permitted to know. It dries under exposure to air in small

scales, is soluble in water but not in alcohol, slightly reddens

litmus paper, and long retains its noxious properties. It has no acrid

or burning taste, and but little if any odor; the tongue pronounces it

inoffensive, and the mucous surface of the alimentary track is proof

against it, and it has been swallowed in considerable quantities

without deleterious result--all the poison that could be extracted

from a half dozen of the largest and most virile reptiles was

powerless in any way to affect an unfledged bird when poured into its

open beak. Chemistry is not only powerless to solve the enigma of its

action, and the microscope to detect its presence, but pathology is at

fault to explain the reason of its deadly effect; and all that we know

is that when introduced even in most minute quantities into an open

wound, the blood is dissolved, so to speak, and the stream of life

paralyzed with an almost incredible rapidity. Without test or

antidote, terror has led to blind, fanatical empiricism, necessarily

attended with no little injury in the search for specifics, and it may

be reasonably asserted that no substance can be named so inert and

worthless as not to have been recommended, or so disgusting as not to

have been employed; nor is any practice too absurd to find favor and

adherents even among the most enlightened of the medical profession,

who have rung all the changes of the therapeutical gamut from

serpentaria[3] and boneset to guaco, cimicifugia, and _Aristolochia

India_ to curare, alum, chalk, and mercury to arsenic; and in the way

of surgical dressings and appliances everything from poultices of

human fæces,[4] burying the part bitten in fresh earth,[5] or

thrusting the member or entire person into the entrails of living

animals, to cupping, ligatures, escharotics, and the moxa.

[Footnote 3: Serpentaria derives its name from its supposed

antidotal properties, and guaco and _Aristolochia India_ enjoyed

widely heralded but rapidly fleeting popularity in the two Indias

for a season. Tanjore pill (black pepper and arsenic) is still

extensively lauded in districts whose serpents possess little

vitality, but is every way inferior to iodine.]

[Footnote 4: A Chinese remedy--as might be imagined.]

[Footnote 5: Still extensively practiced, the first in Michigan,

the latter in Missouri and Arkansas, and inasmuch as one is

cooling and soothing, and the other slightly provocative of

perspiration in the part, are not altogether devoid of

plausibility.]

Although the wounds of venomous serpents are frequently attended with

fatal results, such are not necessarily invariable. There are times

and seasons when all reptiles are sluggish and inactive, and when they

inflict comparatively trifling injuries; and the poison is much less

virulent at certain periods than others--during chilling weather for

instance, or when exhausted by repeated bites in securing sustenance.

Young and small serpents, too, are less virile than large and more

aged specimens, and it has likewise been observed that death is more

apt to follow when the poison is received at the beginning or during

the continuance of the heated term.

The action of the venom is commonly so swift that its effects are

manifested almost immediately after inoculation, being at once

conveyed by the circulatory system to the great nervous centers of the

body, resulting in rapid paralysis of such organs as are supplied with

motive power from these sources; its physiological and toxicological

realizations being more or less speedy accordingly as it is applied

near or remote from these centers, or infused into the capillary or

the venous circulation. Usually, too, an unfortunate experiences,

perhaps instantaneously, an intense burning pain in the member

lacerated, which is succeeded by vertigo, nausea, retching, fainting,

coldness, and collapse; the part bitten swells, becomes discolored, or

spotted over its surface with livid blotches, that may, ultimately,

extend to the greater portion of the body, while the poison appears to

effect a greater or less disorganization of the blood, not by

coagulating its fibrine as Fontana surmised, but in dissolving,

attenuating, and altering the form of its corpuscles, whose integrity

is so essential to life, causing them to adhere to one another, and to

the walls of the vessels by which they are conveyed; being no longer

able to traverse the capillaries, oedema is produced, followed by the

peculiar livid blush. Shakespeare would appear to have had intuitive

perception of the nature of such subtle poison, when he caused the

ghost to describe to Hamlet

"The leprous distillment whose effect

Bears such an enmity to the blood of man

That swift as quicksilver, it courses through

The natural gates and alleys of the body

And with sudden vigor it doth posset

And curd like eager droppings into milk,

The thin and wholesome blood: so did it mine

And a most instant tetter marked about

Most lazar like, with vile and loathsome crust

All my smooth body."

It is not to be supposed, however, that all or even a major portion of

the blood disks require to be changed or destroyed to produce a fatal

result, since death may supervene long before such a consummation can

be realized. It is the capillary circulation that suffers chiefly,

since the very size and caliber of the heart cavities and trunk

vessels afford them comparative immunity. But of the greatly dissolved

and disorganized condition of the blood that may occur secondarily, we

have evidences in the passive hæmorrhages that attack those that have

recovered from the immediate effects of serpent poisoning, following

or coincident with subsidence of swelling and induration; and, as with

scurvy, bleeding may occur from the mouth, throat, lungs, nose, and

bowels, or from ulcerated surfaces and superficial wounds, or all

together, defying all styptics and hæmastatics. In a case occurring

under the care of Dr. David Brainerd in the Illinois General

Hospital,[6] blood flowed from the gums in great profusion, and on

examination was found destitute, even under the microscope, of the

faintest indications of fibrine--the principle upon which coagulation

depends. The breath, moreover, gave most sickening exhalations,

indicative of decomposition, producing serious illness in those

exposed for any length of time to its influence. We may add, among

other sequelæ, aside from death produced through primary and secondary

effects, paralysis, loss of nerve power, impotence, hæmorrhage, even

mortification or gangrene.

[Footnote 6: _Medical Independent_, 1855.]

The failure in myotic power of the heart and in the muscles of

respiration through reflex influence of par vagum and great

sympathetic nerves, whereby pulmonary circulation is impeded, are

among the earliest of phenomena. Breathing becoming retarded and

laborious, the necessary supply of oxygen is no longer received, and

blood still venous, in that it is not relieved of its carbon, is

returned through the arteries, whereby the capillaries of the brain

are gorged with a doubly poisoned circulation, poisoned by both venom

and carbon. In this we have ample cause for the attending train of

symptoms that, beginning with drowsiness, rapidly passes into stupor

followed by profound coma and ultimate dissolution--marked evidence of

the fact that a chemical agent or poison may produce a mechanical

disease; and autopsical research reveals absolutely nothing save the

general disorganization of blood corpuscles, as already noted.

Taking circumstantial and pathological evidences into consideration,

the hope of the person thus poisoned rests solely upon lack of

vitality in the serpent and its venom, and in his personal

idiosyncrasies, habits of life, condition of health, etc., and the

varied chapters of accidents. _To look for a specific, in any sense of

the word, is the utmost folly!_ The action of the poison and its train

of results follow inoculation in too swift succession to be overtaken

and counteracted by any antidote, supposing such to be a possible

product, even if administered hypodermically. We have evidence of this

in iodic preparations, iodine being the nearest approach to a perfect

antidote that can be secured by mortal skill, inasmuch, if quickly

injected into the circulation, it retards and restrains the

disorganizing process whereby the continuity of the blood corpuscles

is lost; moreover, it is a marked antiseptic, favors the production of

adhesive inflammation, whereby lymph is effused and coagulated about

the bitten part, and absorption checked, and the poison rendered less

diffusible. But when a remedy is demanded that shall restore the

pristine form, functions, and energy of the disorganized globules, man

arrogates to himself supernal attributes whereby it becomes possible

not only to save and renew, _but to create life_; and we can scarce

expect science or even accident (as some expect) to even rival Nature

and set at defiance her most secret and subtle laws. Such, however, is

the natural outcropping of an ignorant teaching and vulgar prejudice

that feeds and clothes the charlatan and ascribes to savage and

uncultured races an occult familiarity with pathological,

physiological, and remedial effect unattainable by the most advanced

sciences; and whereby the Negro, Malay, Hindoo, South Sea Islander,

and red man are granted an innate knowledge of poisons and their

antidotes more than miraculous. A reward of more than a quarter of a

century's standing, and amounting to several thousand pounds, is

offered by the East India Government for the discovery of a specific

for the bite of the cobra, and for which no claims have ever been

advanced; and the "snake charmers" or jugglers in whom this superior

knowledge is supposed to center are so well aware of the futility of

specifics, and the risk to which they are subjected, that few venture

to ply their calling without a broad-bladed, keen-edged knife

concealed about the person as a means of instant amputation in case of

accident. Medical and scientific associations of various classes, in

Europe, Australia, America, even Africa, and the East and West Indies,

have repeatedly held out the most tempting lures, and indulged in

exhaustive and costly experimentation in search of specifics for the

wounds of vipers, cobras, rattlesnakes, and the general horde of

venomous reptiles; and all in vain. Even the saliva of man, as well as

certain other secretions, is at times so modified by anger as to rival

the venom of the serpent in fatality, and it has no specific; and a

careful analysis of the pathological relations of such poison proves

that further experimentation and expectation is as irrational as the

pursuit of the "philosopher's stone."

It is an indisputable fact, however, that there are individuals whose

natural or acquired idiosyncrasies permit them to be inoculated by the

most venomous of reptiles without deleterious or unpleasant results,

and Colonel Matthews Taylor[7] knew several persons of this character

in India, and who regarded the bite of the cobra or tic paloonga with

nearly as much indifference as the sting of a gnat or mosquito. Again,

in 1868, Mr. Drummond, a prominent magistrate of Melbourne,

Australia,[8] met with untimely death under circumstances that

attracted no little attention. An itinerant vender of nostrums had on

exhibition a number of venomous reptiles, by which he caused himself

to be successively bitten, professing to secure immunity by reason of

a secret compound which he offered for sale at a round figure.

Convinced that the fellow was an imposter, and his wares valuable only

as a means of depleting the pockets of the credulous, Mr. Drummond

loudly asserted the inefficacy of the nostrum, as well as the

innocuousness of the reptiles, which he assumed to be either naturally

harmless, or rendered so by being deprived of their fangs; and in

proof thereof insisted upon being himself bitten. To this experiment

the charlatan was extremely averse, offering strenuous objections, and

finally conveyed a point blank refusal. But Mr. Drummond's demands

becoming more imperative, and observing that his hesitancy impressed

the audience as a tacit acknowledgment of the allegations, he finally

consented, and placed in the hands of the magistrate a tiger snake,

which he deemed least dangerous, and which instantly struck the

gentleman in the wrist. The usual symptoms of serpent poisoning

rapidly manifested themselves, followed by swelling and lividity of

the part, obstructed circulation and respiration, and coma; and in

spite of the use of the vaunted remedy and the attentions of

physicians the result was most fatal. The vender subsequently conceded

the worthless character of his nostrum, declaring that be enjoyed

exemption from the effects of of serpent poison by virtue of recovery

from a severe inoculation in early life; and he further added he knew

"some people who were born so," who put him "up to this dodge" as a

means of gaining a livelihood.

[Footnote 7: _Vide_ report to Prof. J. Henry Bennett.]

[Footnote 8: London _Times_.]

It is a general supposition that such immunity, when congenital, is

acquired _in utero_ by the inoculation of the parent, and Oliver

Wendell Holmes' fascinating tale of "Elsie Venner" embodies many

interesting features in this connection. Admitting such inoculation

may secure immunity, recent experiments in the action of this as well

as kindred poisons give no grounds for believing it at all universal

or even common, but as depending upon occult physiological or

accidental phenomena. For instance, the writer and his father are

equally proof against the contagion and inoculation of vaccination and

variola, in spite of repeated attempts to secure both, while their

respective mothers suffered terribly with smallpox at periods

subsequent to the birth of their children; and it is well understood

that there are striking analogies between the poisons of certain

contagious fevers and those of venomous serpents, inasmuch as one

attack conveys exemption from future ones of like character. In other

words, many animal poisons, as well as the pathological ones of

smallpox, measles, scarlatina, whooping cough, etc., have the power of

so modifying the animal economy, when it does not succumb to their

primary influence, as to ever after render it all but proof against

them. Witness, for instance, the ravages of the mosquito, that in

certain districts punishes most terribly all new comers, and who after

a brief residence suffer little, the bite no longer producing pain or

swelling.

Regarding the supposed correlation of serpent poison and the septic

ferments of certain tropical and infectious fevers, they are not

necessarily always contagious. It may be interesting to note that one

Doctor Humboldt in 1852,[9] in an essay read before the Royal Academy

of Medical Sciences at Havana, assumed their proximate identity, and

advocated the inoculation of the poison of one as a prophylactic of

the other. He claimed to have personally inoculated numberless persons

in New Orleans, Vera Cruz, and Cuba with exceedingly dilute venom,

thereby securing them perfect immunity from yellow fever. Aside from

the extraordinary nature of the statement, the fact that the doctor

affirmed, he had never used the virus to an extent sufficient to

produce any of its toxic symptoms, cast discredit over the whole, and

proofs were demanded and promised. This was the last of the subject,

however, which soon passed into oblivion, though whether from failure

on the part of the medico to substantiate his assertions, or from the

inanition of his colleagues, it is difficult to determine, though the

presumption is largely in favor of the former. Nevertheless, it is

worthy of consideration and exhaustive experimentation, since it is no

less plausible than the theory which rendered the name of Jenner

famous.

[Footnote 9: London _Lancet_.]

Outside of the transfusion of blood, for which there are strong

reasons for believing would be attended with happy results, the sole

remedies available in serpent poisoning are measures looking to the

prompt cutting off of the circulation of the affected part, and the

direct stimulation of the heart's action and the respiratory organs,

until such a time as Nature shall have eliminated all toxical

evidences; and these must necessarily be mechanical. Alcoholic

stimulants are available only as they act mechanically in sustaining

cardiac and pulmonary activity, and where their free use is prolonged

efficacy is quickly exhausted, and they tend rather to hasten a fatal

result. They are devoid of the slightest antidotal properties, and in

no way modify the activity of the venom; and an intoxicated person, so

far from enjoying the immunity with which he is popularly credited, is

far more apt to succumb to the virus than him of unfuddled intellect.

The reasons are obvious. Theoretically, for purely physiological and

therapeutic reasons _amyl nitrite_ should be of incalculable value,

though I have no knowledge of its use in this connection, since its

vapor when inhaled is a most powerful stimulator of cardiac action,

and when administered by the mouth it is unapproached in its control

of spasmodically contracted vessels and muscles. The relief its vapor

affords in the collapse of chloroform anæsthesia, in which dissolution

is imminent from paralyzed heart's action, is instantaneous, and its

effect upon the spasmodic and suffocative sensations of hydrophobia

are equally prompt. Moreover, without further discussing its

physiological functions, it is the nearest approach to an antidote to

certain zymotic poisons, and especially valuable in warding off and

aborting the action of the ferment that gives rise to pertussis, or

whooping cough. _Iodide of ethyl_ is another therapeutical measure

that is worthy of consideration; and _iodoform_ in the treatment of

the sequelæ incident to recovery.

The native population of India, in spite of the contrary accepted

opinion, are remarkably free from resort to nostrums that lay claim to

being antidotes. The person inoculated by the cobra is at once seized

by his friends, and constant and violent exercise enforced, if

necessary at the point of stick, and severe and cruel (but

nevertheless truly merciful) beatings are often a result. In this we

see a direct application, without in the least understanding them, of

the rules laid down to secure certain physiological results, as for

the relief of opium and morphia narcosis, which serpent poisoning

almost exactly resembles. The late Doctor Spillsbury (Physician-General

of Calcutta),[10] while stationed at Jubulpore, Central India, was

informed late one evening that his favorite horse keeper had just been

dangerously bitten by a cobra of unusual size, and therefore more than

ordinarily venomous. He at once ordered his gig, and in spite of the

wails and protestations of the sufferer and his friends, with whom a

fatal result was already a foregone conclusion, the doctor caused his

wrists to be bound firmly and inextricably to the back of the vehicle;

then assuring the man if he did not keep up he would most certainly be

dragged to death, he mounted to his seat and drove rapidly away. Three

hours later, or a little more, he returned, having covered nearly

thirty miles without cessation or once drawing rein. The horse keeper

was found bathed in profuse perspiration, and almost powerless from

excessive fatigue. _Eau de luce_, an aromatic preparation of ammonia,

was now administered at frequent and regular intervals as a diffusible

stimulant, and moderate though constant exercise enforced until near

dawn, when the sufferer was found to be completely recovered.

[Footnote 10: London _Lancet_.]

The value of violent and profuse cutaneous transpiration, thereby

securing a rapidly eliminating channel for discharging poison from the

system, is well known; in no other way can action be had so thorough,

speedy, and prompt. Captain Maxwell[11] tells us it was formerly the

custom among the Irish peasantry of Connaught, when one manifested

unmistakable evidences of hydrophobia, to procure the death of the

unfortunate by smothering between two feather beds. In one instance,

after undergoing this treatment, the supposed corpse was seen, to the

horror and surprise of all who witnessed it, to crawl from between the

bolsters, when he was found to be entirely free from his disorder; the

beds, however, were saturated through and through with the

perspiration that escaped the body in the intensity of his mortal

agony. More recently a French physician,[12] recognizing the incubatory

stage of rabies in his own person, resolved upon suicide rather than

undergo its attendant horrors. The hot bath was selected for the

purpose, with a view of gradually increasing its temperature until

syncope should be induced, which he hoped would be succeeded by death.

To his surprise, however, as the temperature of the water rose, his

sensations of distress improved; and the very means chosen for

terminating life became instead his salvation, restoring to perfect

health. Again, Dr. Peter Hood[13] relates that a blacksmith residing in

the neighborhood of his country house was in high repute for miles

about by reason of his cures of rabies. His remedy consisted simply in

forcing the person bitten to accompany him in a rapid walk or trot for

twenty miles or more, after which he administered copious draughts of

a hot decoction of broom tops, as much for its moral effect as for its

value in sustaining and prolonging established diaphoresis.

[Footnote 11: Wild Sports or the West.]

[Footnote 12: _L'Union Medicale_--name withheld by request of the

gentleman.]

[Footnote 13: London _Lancet_.]

Though the pathological conditions of hydrophobia and serpent

poisoning are by no means parallel, the _rationale_ of the methods

employed in opening the emunctories of the skin are the same; and were

it not for its powerful protracting effect and depressing action upon

the heart, we might perhaps secure valuable aid from jaborandi

(_pilocarpus_), since it stimulates profusely all the secretions; as

it is, more is to be hoped for in the former disorder than in the

latter. It would be desirable also to know what influence the Turkish

bath might exert, and it would seem worthy at least of trial.

* * * * *

Scientific American Supplement, No. 421, January 26, 1884 · 第 32 / 48 题