XL.

_MADAM,_

Concerning the disease of the Stone, your _Author_ seems to be of an

opinion, That the stone in the Bladder, and the stone in the Kidnies,

are not made after one and the same manner: For, says he,[1] _The

Bladder and the same Urine in number procreates a duelech of another

condition, then that which is made in the Kidney._ And truly, _Madam_,

it may be so; for there are several ways or modes in irregularities,

as well as regularities, and not every kind is alike, no not every

Particular, but there is some difference between them: Wherefore, it

may very well be, that the corporeal motions that make the stone in

the Kidneys, are not just alike to those that make the stone in the

Bladder; and as each sort of stone is different, so their particular

causes ought to be different; but this is to be observed, that

generally all diseases which produce hardness, are made by contracting,

condensing and retenting motions, and therefore the remedies of them

must be dilating, rarifying and dissolving. Next your _Author_ says,

_The Stone is not bred by heat, but heat is rather an effect of the

stone; neither is a certain muscilage, or a slimy, snivelly Phlegme

the cause or matter of the stone, but the stone is the cause of the

phlegme._ But, in my judgment, it seems more probable, that a slimy

matter is more proper for a stone to be made of, then that a stone

should make slime, except it be in its dissolution; that is, when the

stone, as in its generation or production it did change from a slimy

or liquid substance to a stone by condensing and contracting motions,

doth, by dilating and rarifying motions, dissolve again into such a

liquid and slimy body. I will not say always, to wit, that the stone

must needs be resolved into a slimy matter, but oftentimes it may be

so. Neither can I absolutely affirm that either heat or cold onely is

the cause of a stone; for some may be produced by hot, and some by

cold contractions and densations, there being as many several sorts of

stones as there are of other Creatures: But this is to be well noted,

that as some sorts of hot contractions do make stones, so some sorts

of hot dilations do dissolve them: The like of cold contractions and

dilations. Again: your _Author_ speaking of the womb wherein the stone

is made; _Every generated thing or being_, says he, _must of necessity

have a certain place or womb where it is produced; for there must

needs be places wherein things may be made before they are bred._ I

answer: As there is not any body without place, nor any place without

body, so the womb is not the place of the body generated, neither

before nor after its generation, no more then a man can be said to

be in a room when he is not there, but every body carries its place

along with it. Moreover, concerning the voiding of bloody Urine, which

happens sometimes in the disease of the Stone, my opinion is, That

it doth not always proceed from the Stone, but many times from the

breaking or voluntary opening of some Veins. But as for the cure of the

disease of the Stone your _Author,_[2] is pleased to affirm, _That no

disease is incurable_, and so neither the disease of the Stone, _For

he himself has cured many of the Stone to which they had been obedient

for some years._ Indeed, _Madam_, I fear his words are more cheerful

then effectual; however it may be possible, if the Kidneys be no ways

impaired, or the Bladder hurt; but if there be some such imperfection

in either or both, then it is as much, in my opinion, as to say, Man

can do more then Nature doth: Neither can I believe, that then any of

your _Authors_ Chymical preparations, as _Aroph, Ludus, Alkahest_,

and the like, if they were to be had, would do any good, no nor

_Daucus_, or wild Carrot-seed, if the disease be as yet curable, will

prove an effectual remedy for it, although your _Author_ is pleased

to relate an example of a man, to whom it did much good; for I can

affirm the contrary by other the like Examples, that it never did any

good to those that used it; nor the liquor of the Birch-tree, whose

venue and efficacy I do not believe to be so great as your _Author_

describes:[3] But for the stoppage of Urine, Marsh-mallow and oyl of

Almonds, which he despises, I approve to be good, and better then any

of his Unknown, Chymical Secrets; for those Chymical Medicines, as he

himself confesses, are hard to be had, especially _Alkahest_, which is

onely to be obtained by a Particular favour from Heaven, and is rather

a supernatural Gift, then a natural remedy. But your _Author_ doth

wisely, to commend such remedies as can never, or with great difficulty

be obtained, and then to say that no disease is incurable. And so

leaving him to his unknown secrets, and those to them that will use

them, I am resolved to adhere to the Practice of the Schools, which I

am confident will be more beneficial to the health of,

Madam,

_Your real and faithful_

_Friend and Servant._

[1] Of the Stone, _ch._ 6. See the _ch._ called, _A Numero-Critical

Paradox of supplies_.

[2] _Ch._ 7.

[3] _Ch._ 8.

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