SIR,

Permit me to send the following case to you for insertion in the

Gazette.

Mary Blores, æt. 33, was admitted into the Middlesex Hospital on

the 16th of November. She was in a state of extreme feebleness and

emaciation. Those who brought her said that during the preceding

month she had appeared to swallow nothing: what she took as food

seemed to her to stop in the gullet, and after a few minutes

returned. I found, however, that a large œsophagus-bougie passed

readily into the stomach, meeting with no obstruction beyond a

spasmodic resistance in the pharynx. A draught of milk and water

was given her--she swallowed it without much effort, but it quickly

returned. In the course of the afternoon a pint of beef tea was

injected through an elastic tube into the stomach--it was thrown up

directly.

I now learnt from her that she could swallow liquids much more

readily than solid food; that when she took a small quantity,

it seemed to her not to reach the stomach, and in three or four

minutes was invariably thrown up; that on taking a large draught

she had an impression that it reached the stomach--in this case

vomiting did not follow so soon, and some part of the draught was

permanently retained; that she craved food and drink, and was

literally dying of hunger and thirst; that the vomiting which took

place was not preceded by nausea, although in its progress it had

all the appearance of ordinary retching; that the matter vomited

was not thrown up at once, but by successive efforts; it consisted

of the food she had last taken, mixed with colourless mucus. The

belly was so shrunk that the umbilicus was not more than an inch

distant from the spine, upon which the pulsations of the aorta

were readily felt: there was no enlargement or hardness about the

stomach, no particular tenderness on pressing the epigastrium, no

sensation of pain or heat now or formerly.

The complaint had began ten years ago, during pregnancy, since when

she had never been free from it, although at times her sufferings

had been less, and she had been able to retain some portion of her

meals. She had borne in this period three children; the vomiting

had lasted during the whole period of her pregnancies, and during

her confinement. The principal remedies which had been used for her

relief were a succession of blisters on the pit of the stomach--but

they had produced no benefit. Latterly her symptoms had been

greatly aggravated.

This patient was attended by Dr. Watson and myself. But the means

which we tried to enable her to retain her food, and to support her

expiring strength, had scarcely a temporary effect. She died on the

2d Dec. sixteen days after her admission. The body was carefully

examined, at the expressed wish of her relatives.

The unusual appearances found in the abdomen were--1. the smallness

of the first part of the duodenum, which was but half the ordinary

size of the ileum; 2. the capaciousness and fulness of the gall

bladder,--from which, however, on compressing it, the bile flowed

readily into the intestine; 3. a contraction of the middle of

the stomach of the length of two inches, for which extent the

peritoneal coat was thickened and opaque, and the inner membranes

folded in deep longitudinal rugæ, the mucous surface of which was

partially suffused with circular spots of red. The breadth of the

contracted part of the stomach, as it lay collapsed, was an inch

and a half.

[Illustration]

[Illustration]

But it was in the chest that the most remarkable circumstance

presented itself. The œsophagus gradually enlarged from the

pharynx, which was perhaps rather narrower than usual, to an

extraordinary degree of dilatation; the greatest breadth which it

attained was situated about four inches above the cardia: the tube

then contracted more abruptly, so as to render the termination

of the œsophagus, like its commencement, of nearly the usual

dimensions. The structure likewise of the cardiac extremity for

about an inch, and of the pharyngeal end for about half an inch,

was healthy. The intermediate part presented, when inverted, the

following curious appearance:--The inner membrane was thickened

and opaque, and had _the appearance_ of having partially yielded

from dilatation; at the upper part the furrows or thinner parts of

the membrane followed in some degree a longitudinal direction; at

the lower part the surface was pitted with shallow depressions of

various figures. I have represented in the adjoined sketches these

appearances, which on the middle of the œsophagus passed from one

into the other; at the furrows or depressions the membrane seemed

of the natural thickness and colour; the intermediate raised and

thickened part was opaque and whitish. The muscular fibres of the

œsophagus were of the natural colour and thickness.

I remain, Mr. Editor,

Your obedient servant,

The London Medical Gazette; December 27, 1828 Being a Weekly Journal of Medicine and the Collateral Sciences · 第 10 / 58 题