_Isabel I of Castilla_.--Born at Madrigal de las Altas Torres
(Avila), April 22, 1451; daughter of Juan II of Castilla and Isabel of
Portugal. Married Fernando II of Aragón, Oct. 18 or 19, 1469. Succeeded
her brother Enrique IV on the throne of Castilla and Leon; proclaimed
queen Dec. 13, 1474. Died at Medina del Campo (Valladolid), Nov. 26,
1504. Named as her heirs her daughter Juana and the latter's husband,
Philip of Austria; and appointed Fernando (now V of Castilla) regent of
Castilla and León during the minority of Juana's son Cárlos. Fernando
and Isabel were styled "the Catholic Sovereigns."
_Fernando V of Castilla_ (II of Aragón and Navarra).--Born at Sos
(Zaragoza), May 10, 1452; son of Juan II and Juana Enriquez of Aragón
and Navarra. Died at Madrigalejo, Jan. 23, 1516. During Isabel's life,
was king-consort, and governed her dominions only by virtue of this
relation; after her death, was regent only of Castilla, which dignity
he held until his death, except from June 27, 1506, to Aug. 21, 1507,
during which period he retired to Aragón, in favor of Juana's husband
Philip. Inheriting the throne of Aragón and Navarra (Jan. 20, 1479),
his marriage with Isabel (1469) and their conquest of Granada (1492)
united under one monarchy the provinces now comprised in the country
of Spain.
_Juana_.--Born at Toledo, in 1479; second daughter of Isabel and
Fernando. Married Philip of Austria, Oct. 20 or 21, 1496. Died at
Tordesillas, April 11, 1555. Reigned from Nov. 26, 1504, until her
death--jointly with her husband, during his life; and with her son
thereafter--but under her father's regency until 1516; during her reign
she was more or less subject to insanity, and was but nominally queen,
seldom exercising royal powers, and living in strict seclusion. Known
as "la Loca," "the Mad."