SEMEN ISPAGHULÆ.

_Ispaghúl Seeds_, _Spogel Seeds_.

=Botanical Origin=—_Plantago decumbens_ Forsk. (_P. Ispaghula_

Roxb.),[1795] a plant of variable aspect, from an inch to a foot in

height, erect or decumbent, with linear lanceolate leaves which may be

nearly glabrous, or covered with shaggy hairs. The flower-spikes differ

according to the luxuriance of the plant, being in some specimens

cylindrical and 1½ inches long, in others reduced to a globular

head. The plant has a wide range, occurring in the Canary Islands,

Egypt, Arabia, Beluchistan, Afghanistan, and North-western India.

Stewart[1796] says it is common in the Peshawar valley and Trans-Indus

generally up to 2000 feet; also on the plains and lower hills of the

Punjab, but that he has never seen it cultivated in the latter region.

It is said to be cultivated at Multan and Lahore, also in Bengal and

Mysore.

=History=—The seeds which are found in all the bazaars of India and

are held in great esteem, are generally designated by the Persian word

_Ispaghúl_; but they also bear the Arabic name _Bazre-qatúná_, under

which we find them mentioned by the Persian physician Alhervi[1797]

in the 10th century, and about the same period or a little later by

Avicenna.[1798] Several other Oriental writers are quoted by Ibn

Baytar[1799] as referring to a drug of the same name, which may

possibly have included the seeds of other species, as _Plantago

Psyllium_ L. and _P. Cynops_, having similar properties, and known to

have been used from an early period.

J. H. Linck, whom we mentioned in our article on Oleum Cajuputi (p.

278), described in 1719 the seed under notice, yet without knowing its

name; it further attracted the notice of Europeans towards the close of

the last century,[1800] and has been often prescribed as a demulcent in

dysentery and diarrhœa. It was admitted to the _Pharmacopœia of India_

of 1868.

[1795] After the examination of numerous specimens, we adopt the

course taken by Dr. Aitchison (_Catalogue of the Plants of the Punjab

and Sindh_, Lond. 1869) of uniting _P. Ispaghula_ to _P. decumbens_.

The union of species in this group may probably be carried still

further.—For a fig. see Bentley and Trimen, _Med. Plants_, part 21

(1877).

[1796] _Punjab Plants_, Lahore 1869. 174—also MS. note attached to

specimens in Herb. Kew.

[1797] _Liber Fundamentorum Pharmacologiæ_, ed. Seligmann, Vindobonæ,

1830. 40.

[1798] Lib. ii. tract. 2. c. 541. (Valgrisi edition, 1564. i. 357.)

[1799] Sontheimer’s transl. i. (1840) 132.

[1800] Fleming, _Catal. of Indian Med. Plants and Drugs_, Calcutta,

1810. 31.

=Description=—The seeds, like those of other species of _Plantago_, are

of boat-shaped form, the albumen being deeply furrowed on one side and

vaulted on the other. They are a little over ⅒ of an inch in length

and nearly half as broad, and so light that 100 weigh scarcely three

grains. Their colour is a light pinkish grey with an elongated brown

spot on the vaulted back, due to the embryo, which at this point is

in close contact with the translucent testa. From this brown spot the

thick radicle runs to the top of the seed. The hollow side of the seed

is also brown and partially covered with a thin white membrane.

The seeds are highly mucilaginous in the mouth, but have neither taste

nor odour. Those of the allied _P. Psyllium_ have nearly the same form,

but are shining and of a dark brown hue.

=Microscopic Structure=—This can be best investigated by immersing

the seed in benzol, as in this medium the mucilage is insoluble. When

thus examined, the whole surface is seen to consist of polyhedral

cells, separated by a very thin brown layer from the albumen, which

on the back of the seed is only 70 mkm. thick. The albumen is made up

of thick-walled cells, loaded with granules of matter which acquire

an orange hue on addition of iodine. The two cotyledons adhere in a

direction perpendicular to the bottom of the furrow; their tissue is

composed of thin-walled smaller cells, containing also albuminous

granules and drops of fatty oil.

If the seed is immersed in water, the cells composing the epidermis

instantly swell and elongate, and soon burst, leaving only fragments of

their walls. When examined under glycerin, the change is more gradual,

and the outer walls of the cells yielding the mucilage display a series

of thin layers, which slowly swell and disappear by the action of

water. The mucilage is consequently not contained within the cells, but

is formed of the secondary deposits on their walls, as in linseed and

quince pips.

=Chemical Composition=—Mucilage is so abundantly yielded by these

seeds, that one part of them with 20 parts of water forms a thick

tasteless jelly. On addition of a larger quantity of water and

filtering, but little mucilage passes, the greater part of it adhering

to the seeds. The mucilage separated by straining with pressure does

not redden litmus, is not affected by iodine, nor precipitated by

borax, alcohol or ferric chloride. The fat oil and albuminous matter of

the seed have not been examined.

=Uses=—A decoction of the seeds (1 p. to 70 p. of water) is employed in

India as a cooling, demulcent drink. The seeds powdered and mixed with

sugar, or made gelatinous with water, are sometimes given in chronic

diarrhœa.

Pharmacographia A history of the principal drugs of vegetable origin, met with in Great Britain and British India · 第 232 / 340 题