RADIX SUMBUL.

_Sumbul Root_; F. _Racine de Sumbul_, _Sambola ou Sambula_; G.

_Moschuswurzel_.

=Botanical Origin=—_Ferula Sumbul_ Hooker fil. (_Euryangium Sumbul_

Kauffmann[1190]), a tall perennial plant discovered in 1869 by a

Russian traveller, Fedschenko, in the mountains of Maghian near

Pianjakent, in the northern part of the Khanat of Bukhara, nearly 40°

N. lat., and 68° to 69° E. long. From Wittmann’s statements (1876) it

would appear that the Sumbul plant abounds far east from that country,

in the coast province of the Amoor. A living plant transmitted from the

former district to the Botanical Garden of Moscow flowered there in

1871, another in 1875 at Kew, where the plant died after flowering.

[1190] _Nouv. Mém. de la Soc. imp. des Nat. de Moscou_, xii. (1871)

253. tabb. 24. 25.—Also figured in Bentley and Trimen, _Med. Plants_,

part 20 (1877).

=History=—The word _sumbul_, which is Arabic and signifies _an ear_

or _spike_, is used as the designation of various substances, but

especially of _Indian Nard_, the rhizome of _Nardostachys Jatamansi_

DC. Under what circumstances, or at what period, it came to be applied

to the drug under notice, we know not. Nor are we better informed as to

the history of sumbul root, which we have been unable to trace by means

of any of the works at our disposal. All we can say is, that the drug

was first introduced into Russia about the year 1835 as a substitute

for musk, that it was then recommended as a remedy for cholera, and

that it began to be known in Germany in 1840, and ten years afterwards

in England. It was admitted into the _British Pharmacopœia_ in 1867.

=Description=—The root as found in commerce consists of transverse

slices, 1 to 2 inches, rarely as much as 5 inches in diameter, and

an inch or more in thickness; the bristly crown, and tapering lower

portions, often no thicker than a quill, are also met with. The outside

is covered by a dark papery bark; the inner surface of the slices is of

a dirty brown, marbled with white, showing when viewed with a lens an

abundant resinous exudation, especially towards the circumference. The

interior is a spongy, fibrous, farinaceous-looking substance, having a

pleasant musky odour and a bitter aromatic taste.

=Microscopic Structure=—The interior tissue of sumbul root is very

irregularly constructed of woody and medullary rays, while the cortical

part exhibits a loose spongy parenchyme. The structural peculiarity of

the root becomes obvious, if thin slices are moistened with solution

of iodine, when the medullary rays assume by reason of the starch they

contain an intense blue. The structure of the root differs from the

usual arrangement by the formation of independent secondary cambial

zones with fibro-vascular bundles within the original cambium. Similar

peculiarities are also displayed by the roots of Myrrhis odorata,

Convolvulus Scammonia, Ipomœa Turpethum and others.[1191] Large

balsam-ducts are also observable in Sumbul as well as in the roots of

many other Umbelliferæ.[1192]

=Chemical Composition=—Sumbul root yields about 9 per cent. of a soft

balsamic resin soluble in ether, and ⅓ per cent. of a dingy bluish

essential oil. The resin has a musky smell, not fully developed until

after contact with water. According to Reinsch (1848), it dissolves in

strong sulphuric acid with a fine blue colour, but in our experience

with a crimson brown. The same chemist states that when subjected to

dry distillation, it yields a blue oil.

Solution of potash is stated to convert the resin of sumbul into a

crystalline potassium salt of _Sumbulamic Acid_, which latter was

obtained in a crystalline state by Reinsch in 1843, but has not been

further examined. Sumbulamic acid, which smells strongly of musk,

appears to be a different substance from _Sumbulic_ or _Sumbulolic

Acid_, the potassium salt of which may be extracted by water from the

above-mentioned alkaline solution. Ricker and Reinsch (1848), assert

that the last-mentioned acid, of which the root contains about ¾ per

cent., is none other than _Angelic Acid_, accompanied, as in angelica

root, by a little valerianic acid. All these substances require

further investigation, as well as the body called _Sumbulin_, which

was prepared by Murawjeff (1853), and is said to form with acids,

crystalline salts.

Sommer has shown (1859) that by dry distillation, sumbul resin

yields _Umbelliferone_, which substance we shall further notice when

describing the constituents of galbanum.

=Uses=—Prescribed in the form of tincture as a stimulating tonic.

[1191] See A. de Bary, _Anatomie_, 1877. 623.

[1192] The structure and growth of Sumbul root have been elaborately

studied by Tchistiakoff, of whose observations, first published in

Russian in 1870, an Italian translation with two plates has appeared in

the _Nuovo Giornale Botanico_ for Oct. 1873. 298.

=Adulteration=—_Bombay Sumbul_, or “_Boi_,” is the root of Dorema

Ammoniacum (see article Ammoniacum, p. 324), which is largely

imported into Bombay, being used there in the Parsee fire temples as

an incense.[1193] The largest roots, for which we are indebted to

Professor Dymock, are three inches in diameter at the crown, by 8

inches in length. They are easily distinguished from the Sumbul by

their decidedly yellowish hue as well as by the absence of any musky

odour. We extracted by alcohol, from the root dried at 100° C., 26 per

cent. of a resin identical with that afforded by commercial Ammoniacum.

Bombay Sumbul agrees with the _Indian Sumbul_ as described by

Pereira.[1194]

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