FOLIA CONII.

_Hemlock Leaves_; F. _Feuilles de Ciguë_; G. _Schierlingsblätter_.

=Botanical Origin=—_Conium maculatum_ L., see p. 299.

=History=—See p. 299.

=Description=—Hemlock in its first year produces only a tuft of leaves;

but in its second a stout erect stem which often grows to the height

of 5 or 9 feet, is much branched in its upper part, and terminates in

small umbels, each having about 12 rays. The lower leaves, often a foot

in length, have a triangular outline, and a hollow stalk as long as the

lamina, clasping the stem at its base with a membranous sheath. Towards

the upper portion of the plant, the leaves have shorter stalks, are

less divided, and are opposite or in cohorts of 3 to 5. The involucral

bracts are lanceolate, reflexed, and about a ¼ of an inch long. Those

of the partial umbel are turned towards the outside, and are always 3

in number. The larger leaves are twice or thrice pinnate, the ultimate

segments being ovate-oblong, acute, and deeply incised.

The stem is cylindrical and hollow, of a glaucous green, generally

marked on its lower part with reddish-brown spots. The leaves are of a

dull dark green, and like the rest of the plant quite glabrous. They

have when bruised a disagreeable fœtid smell.

For medicinal purposes the plant should be taken when in full

blossom.[1152]

=Chemical Composition=—The leaves of hemlock contain, though in

exceedingly small proportion, the same alkaloids as the fruits. Geiger

obtained from the fresh herb not so much as one ten-thousandth part

of conine. It is probable however that the active constituents vary

in proportion considerably, and that a dry and sunny climate promotes

their development.

The same observer, as well as Pereira, has pointed out that hemlock

leaves when dried are very frequently almost devoid of conine, and

the observation is supported by the more recent experiments of Harley

(1867). It has also been shown by the last named physician, that the

inspissated juice known in pharmacy as _Extractum Conii_ usually

contains but a mere trace of alkaloid, the latter having in fact been

dissipated by the heat employed in reducing the juice to the required

consistence. On the other hand, Harley has proved that the juice of

fresh hemlock preserved by the addition of spirit of wine, as in the

_Succus Conii_ of the Pharmacopœia, possesses in an eminent degree the

poisonous properties of the plant.

[1150] _Trans. of the New York State Medical Society_ for 1867.

[1151] _The old Vegetable Neurotics_, Lond. 1869.

[1152] The London herbalists often collect it while much of the

inflorescence is still in bud, in which state it affords far more of

leaf than when well matured; but it is in the latter condition that the

plant is to be preferred.

The entire amount of nitrogen in dried hemlock leaves was estimated by

Wrightson (1845) at 6·8 per cent.; the ash at 12·8 per cent. The latter

consists mainly of salts of potassium, sodium, and calcium, especially

of sodium chloride and calcium phosphate.

A ferment-oil may be obtained from _Conium_; it is stated to have an

odour unlike that of the plant and a burning taste, and not to be

poisonous.[1153]

[1153] Gmelin, _Chemistry_, xiv. 405.

=Uses=—Hemlock administered in the form of _Succus Conii_, has a

peculiar sedative action on the motor nerves, on account of which it

is occasionally prescribed. It was formerly much more employed than at

present, although the preparations used were so defective that they

could rarely have produced the specific action of the medicine.

=Plants liable to be confounded with Hemlock=—Several common plants of

the order _Umbelliferæ_ have a superficial resemblance to _Conium_, but

can be discriminated by characters easy of observation. One of these is

_Æthusa Cynapium_ L. or _Fool’s Parsley_, a common annual garden weed,

of much smaller stature than hemlock. It may be known by its primary

umbel having no involucre, and by its partial umbel having an involucel

of 2 or 3 linear pendulous bracts. The ridges of its fruit moreover are

not wavy or crenate as in hemlock, nor is its stem spotted.

_Chærophyllum Anthriscus_ L. (_Anthriscus vulgaris_ Pers.) and two

or three other species of _Chærophyllum_ have the lower leaves not

unlike those of hemlock, but they are _pubescent_ or _ciliated_. The

fruits too are _linear-oblong_, and thus very dissimilar from those of

_Conium_.

The latter plant is in fact clearly distinguished by its smooth spotted

stem, the character of its involucral bracts and fruit, and finally by

the circumstance that when triturated with a few drops of solution of

caustic alkali, it evolves conine (and ammonia), easily observable as

a white fume when a rod moistened with strong acetic acid is held over

the mortar.

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