FRUCTUS CASSIÆ FISTULÆ.

_Cassia Fistula_; _Purging Cassia_; F. _Casse Canefice_, _Fruit du

Caneficer_; G. _Röhrencassie_.

=Botanical Origin=—_Cassia Fistula_ L. (_Cathartocarpus Fistula_

Pers., _Bactyrilobium Fistula_ Willd.) a tree indigenous to India,

ascending to 4000 feet in the outer Himalaya, but now cultivated or

subspontaneous in Egypt, Tropical Africa,[852] the West Indies and

Brazil. It is from 20 to 30 feet high (in Jamaica even 50 feet) and

bears long pendulous racemes of beautiful fragrant, yellow flowers.

Some botanists have established for this tree and its near allies a

separate genus, on account of its elongated, cylindrical indehiscent

legume, but by most it is retained in the genus _Cassia_.

[849] _Op. cit._ (See p. 218).

[850] _Dispensatory_, ed. 2. 1848. 850.

[851] The reader will find figures of these leaves contrasted with

Senna in Pereira’s _Elem. of Mat. Med._ ii. part ii (1853) 1866.

[852] Schweinfurth found it in 6° N. lat. and 28-29° E. long., in the

country of the Dor, where the tree may also be indigenous.

=History=—The name _Casia_ or _Cassia_ was originally applied

exclusively to a bark related to cinnamon which, when rolled into a

tube or pipe, was distinguished in Greek by the word σῦριγζ, and in

Latin by that of _fistula_. Thus Scribonius Largus,[853] a physician

of Rome during the reigns of Tiberius and Claudius, with the latter of

whom he is said to have visited Britain, A.D. 43, uses the expression

“_Casiæ rufæ fistularum_” in the receipt for a collyrium. Galen[854]

describing the different varieties of cassia, mentions that called

_Gizi_[855] (γίζεις) as being quite like cinnamon or even better; and

also names a well-known cheaper sort, having a strong taste and odour

which is called _fistula_, because it is rolled up like a tube.

Oribasius, physician to the Emperor Julian in the latter half of the

4th and beginning of the 5th century, describes _Cassia fistula_ as

a _bark_ of which there are several varieties, having pungent and

astringent properties (“_omnes cassiæ fistulæ vires habent acriter

exalfacientes et stringentes_”), and sometimes used in the place of

cinnamon.[856]

It is doubtless the same drug which is spoken of by Alexander

Trallianus[857] as Κασίας σῦριγζ (_casia fistula_) in connexion with

costus, pepper and other aromatics; and named by other Greek writers as

Κασία συριγγώδης (_casia fistularis_). Alexander still more distinctly

calls it also Κασία αἰγυπτία.[858]

The tree under examination and its fruit were exactly described in the

beginning of the 13th century by Abul Abbâs Annâbatî of Sevilla;[859]

the fruit, the Cassia Fistula of modern medicine, is noticed by Joannes

Actuarius, who flourished at Constantinople towards the close of the

13th century; and as he describes it with particular minuteness,[860]

it is evident that he did not consider it well known. The drug is also

mentioned by several writers of the school of Salernum. The tree would

appear to have found at an early period its way to America, if we are

correct in referring to it the Cassia Fistula enumerated by Petrus

Martyr among the valuable products of the New World.[861] The drug was

a familiar remedy in England in the time of Turner, 1568.[862]

The tree was figured in 1553 by the celebrated traveller Belon who met

with it in the gardens of Cairo, and in 1592 by Prosper Alpinus who

also saw it in Egypt.

=Description=—The ovary of the flower is one-celled with numerous

ovules, which as they advance towards maturity become separated by

the growth of intervening septa. The ripe legume is cylindrical, dark

chocolate-brown, 1½ to 2 feet long by ¾ to 1 inch in diameter, with

a strong short woody stalk, and a blunt end suddenly contracted into

a point. The fibro-vascular column of the stalk is divided into two

broad parallel seams, the dorsal and ventral sutures, running down

the whole length of the pod, The sutures are smooth, or slightly

striated longitudinally; one of them is formed of two ligneous bundles

coalescing by a narrow line. If the legume is curved, the ventral

suture commonly occupies its inner or concave side. The valves of the

pods are marked by slight transverse depressions (more evident in

small specimens) corresponding to the internal divisions, and also by

inconspicuous transverse veins.

[853] _Compositiones Medicamentorum_, cap. 4. sec. 36.

[854] _De Antidot._ i. c. 14.

[855] Noticed likewise among the commodities liable to duty at

Alexandria in the 2nd century.—Vincent, _Commerce of the Ancients_, ii.

712.

[856] _Physica Hildegardis_, Argent. 1533. 227.

[857] Libri xii. J. Guinterio interprete, Basil., 1556. lib. vii. c. 8.

[858] Puschmann’s edition (quoted in the appendix) i. 435.

[859] Meyer, _Geschichte der Botanik_, iii. (1856). 226.

[860] “Quemadmodum si ventrem mollire fuerit animus, pruna, et præcipué

Damascena adjicimus, atque quippiam feré nigræ nominatæ casiæ. Est

autem fructus ejus fistulus et oblongus, nigrum intus humorem concretum

gestans, qui haudquaquam una continuitate coaluit, sed ex intervallo

tenuibus lignosisque membranulis dirimitur, habens ad speciei

propagationem, grana quædam seminalia, siliquæ illi quæ nobis innotuit,

adsimilia.”—_Methodus Medendi_, lib. v. c. 2.

[861] _De nuper sub D. Carolo repertis insulis_, Basil. 1521.

[862] _Herball_, part. 3. 20.

Each of the 25 to 100 seeds which a legume contains, is lodged in a

cell formed by very thin woody dissepiments. The oval, flattish seed

from ³/₁₀ to ⁴/₁₀ of an inch long, of a reddish-brown colour, contains

a large embryo whose yellowish veined cotyledons cross diagonally, as

seen on transverse section, the horny white albumen. One side is marked

by a dark line (the raphe). A very slender funicle attaches the seed to

the ventral suture.

In addition to the seeds, the cells contain a soft saccharine pulp

which in the recent state fills them up, but in the imported pods

appears only as a thin layer, spread over the septum, of a dark viscid

substance of mawkish sweet taste. It is this pulp which is made use of

in pharmacy.

=Microscopic Structure=—The bands above described running along the

whole pod, are made up of strong fibro-vascular bundles mixed with

sclerenchymatous tissue. The valves consist of parenchymatous cells,

and the whole pod is coated with an epidermis exhibiting small tabular

cells, which are filled with dark granules of tannic matter. A few

stomata are also met with. The thin brittle septa of the pod are

composed of long ligneous cells, enclosing here and there crystals of

oxalate of calcium.

The pulp itself, examined under water, is seen to consist of loose

cells, not forming a coherent tissue. They enclose chiefly granules of

albuminoid matters and stellate crystals of oxalate of calcium. The

cell-wall assumes, on addition of iodine, a blue hue if they have been

previously washed by potash lye. The seeds are devoid of starch, but

yield a copious amount of thick mucilage, which surrounds them like a

halo if they are macerated in water.

=Chemical Composition=—No peculiar principle is known to exist either

in the woody or the pulpy portion of cassia fistula. The pulp contains

sugar in addition to the commonly occurring bodies noticed in the

previous section.

=Uses=—The pulp separated from the woody part of the pods by crushing

the latter, digesting them in hot water, and evaporating the strained

liquor, is a mild laxative in common domestic use in the South of

Europe,[863] but in England scarcely ever now administered except in

the form of the well-known _Lenitive Electuary_ (_Confectio sennæ_) of

which it is an ingredient.

=Commerce=—Cassia fistula is shipped to England from the East and

West Indies, but chiefly from the latter. The pulp _per se_ has been

occasionally imported, but it should never be employed when the legumes

for preparing it can be obtained.

=Substitutes=—The pods of some other species of _Cassia_ share the

structure above described and have been sometimes imported.

[863] Thus there were imported into Leghorn in 1871, 103 tons of

_Cassia Fistula_ and Tamarinds.—_Consular Reports_, 1873, part i.

Those of _C. grandis_ L. f. (_C. brasiliana_ Lamarck), a tree of

Central America and Brazil, are of much larger size, showing when

broken transversely an elliptic outline, whose longer diameter exceeds

an inch. The valves have very prominent sutures and transverse

branching veins. The pulp is bitter and astringent.

The legumes of _Cassia moschata_ H B K.,[864] a tree 30 to 40 feet

high, growing in New Granada and known there as _Cañafistola de

purgar_, bear a close resemblance to those of _Cassia Fistula_ L.,

except that they are a little smaller and rather less regularly

straight. They contain a sweetish astringent pulp of a bright brown

hue. When crushed and exposed to the heat of a water-bath, they emit

a pleasant odour like sandal-wood. The pulp is coloured dark blackish

green by perchloride of iron.

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