LIGNUM GUAIACI.

_Lignum sanctum_; _Guaiacum Wood_, _Lignum Vitæ_; F. _Bois de Gaïac_;

G. _Guaiakholz_, _Pockholz_.

=Botanical Origin=—This wood is furnished by two West Indian species of

_Guaiacum_, namely:—

1. _G. officinale_ L., a middle-sized or low evergreen tree, with

light blue flowers, parapinnate leaves having ovate, very obtuse

leaflets in 2, less often in 3 pairs, and 2-celled fruits. It grows in

Cuba, Jamaica (abundantly on the arid plains of the south side of the

island), Les Gonaives in the N.W. of Hayti (plentiful), St. Domingo,

Martinique, St. Lucia, St. Vincent, Trinidad, and the northern coast

of the South American continent. This tree affords the Lignum Vitæ of

Jamaica (of which very little is imported), a portion of that shipped

from the ports of Hayti, and probably the small quantity exported by

the United States of Colombia.

2. _G. sanctum_ L., a tree much resembling the preceding, but

distinguishable by its leaves having 3 to 4 pairs of leaflets which

are very obliquely obovate or oblong, passing into rhomboid-ovate, and

mucronulate; and a 5-celled fruit. It is found in Southern Florida, the

Bahama Islands, Key West, Cuba, St. Domingo (including the part called

Hayti) and Puerto Rico, and is certainly the source of the small but

excellent Lignum Vitæ exported from the Bahamas as well as of some of

that shipped from Hayti.

=History=—There can be no doubt but that the earliest importations

of Lignum Vitæ were obtained from St. Domingo, of which island,

Oviedo[403] who landed in America in 1514 mentions the tree, under the

name of _Guayacan_, as a native. He points out its fruits as yellow and

resembling two joined lupines, which could only be said with reference

to _G. officinale_, and would not apply to the ovoid five-cornered

fruits of _G. sanctum_. Oviedo appears however to have been aware of

two species, one of which he found in Española (St. Domingo) as well as

in Nagrando (Nicaragua) and the other in the island of St. John (Puerto

Rico), whence it was called _Lignum sanctum_.

The first edition of Oviedo was printed in 1526; but some years before

this the wood must have been known in Germany, as is evident by the

treatises written in 1517, 1518, and 1519 by Nicolaus Poll,[404]

Leonard Schmaus[405] and Ulrich von Hutten.[406] The last which gives

a tolerable description of the tree, its wood, bark, and medicinal

properties, was translated into English in 1533 by Thomas Paynel, canon

of Merton Abbey, and published in London in 1536 under the title—“_Of

the wood called Guaiacum that healeth the Frenche Pockes and also

helpeth the gout in the feete, the stoone, the palsey, lepree, dropsy,

fallynge euyll, and other dyseases._” It was several times reprinted.

In the old pharmacy the products of destructive distillation of

guaiacum wood were known as _Oleum ligni sancti_. It must have

consisted of the substances which we mention further on in the

following article.

=Description=—The wood (always known in commerce as _Lignum Vitæ_) as

imported consists of pieces of the stem and thick branches, usually

stripped of bark, and often weighing a hundredweight each. It is

remarkably heavy and compact. Its sp. gr. which exceeds that of most

woods is about 1·3.

Lignum Vitæ is mostly imported for turnery,[407] and the chips,

raspings and shavings are the only form in which it is commonly seen in

pharmacy. A stem 7 to 8 inches in diameter cut transversely exhibits a

light-yellowish zone of sapwood about an inch wide, enclosing a sharply

defined heartwood of a dark greenish brown. Both display alternate

lighter and darker layers, which especially in the sapwood are further

distinguished by groups of vessels. In this manner are formed a large

number of circles resembling annual rings, the general form of which

is evident, though the individual rings are by no means well defined.

More than 20 such rings may be counted in the sapwood of a log such

as we have mentioned, and more than 30 in the heartwood. The pithless

centre is usually out of the axis. The medullary rays are not visible

to the naked eye, but may be seen by a lens to be very numerous and

equidistant. The pores of the heartwood may be distinguished as

containing a brownish resin, while those of the outermost layer of

sapwood are empty.

[403] _Natural Hystoria de las Indias_, Toledo, 1526. fol. xxxvii.

[404] _Decura Morbi Gallici per Lignum Guayacanum libellus_, printed in

1535 but dated 19 Dec. 1517, 8 pages 8°.

[405] _De Morbo Gallico tractatus_, Salisburgi, November

1518,—reprinted in the _Aphrodisiacus_ of Luisinus, Lugd. Bat. 1728.

383.—We have only seen the latter.

[406] _Ulrichi de Hutten equitis de Guaiaci medicina et morbo gallico

liber unus_, 4°. (26 chapters) Moguntiæ, 1519.

[407] It is much used for the wheels (technically “_sheaves_”) of

ships’ blocks (pulleys), the circumference of which ought to consist of

the white sapwood. It is also required for caulking mallets, skittle

balls and for the large balls used in American bowling alleys, for

which purposes it should be as sound and homogeneous as possible.

In the thickest pieces sapwood is wanting, and even in stems of about a

foot in diameter it is reduced to ⅕ of an inch. It is of looser texture

than the heartwood and floats on water, whereas the latter sinks. Both

sapwood and heartwood owe their tenacity to an extremely peculiar

zigzag arrangement[408] of the woody bundles. The sapwood is tasteless.

The heartwood has a faintly aromatic and slightly irritating taste, and

when heated or rubbed emits a weak agreeable odour.

The bark which was formerly officinal but is now almost obsolete, is

very rich in oxalate of calcium and affords upon incineration not less

than 23 per cent. of ash. It contains a resin distinct from that of the

wood, and also a bitter acrid principle.[409]

The Lignum Vitæ of Jamaica (_G. officinale_) and that of the Bahamas

(_G. sanctum_), of which authentic specimens have been kindly placed at

our disposal by Mr. G. Shadbolt, display the same appearance as well as

microscopic structure.[410]

=Microscopic Structure=—The wood consists for the most part of pointed,

not very long, ligneous cells (libriform), traversed by one-celled

rows of medullary rays. There are also thin layers of parenchymatous

tissue, to which the zones apparent in a transverse section of the

drug are due. The pitted vessels are comparatively large but not very

numerous. The structure of the sapwood is the same as that of the

heartwood, but in the latter the ligneous cells are filled with resin.

The parenchymatous cells contain crystals of oxalate of calcium.

=Chemical Composition=—The only constituent of any interest is the

resin which the heartwood contains to the extent of about a fourth of

its weight. The sapwood afforded us 0·91 and the heartwood 0·60 per

cent. of ash.

=Commerce=—Lignum Vitæ varies much in estimation, according to size,

soundness, and the cylindrical form of the logs. The best is exported

from the city of Santo Domingo, whither it is brought from the interior

of the island. The quantity shipped from this port during 1871 was 1494

tons;[411] 220 tons were exported in 1877 from Puerto Plata on the

northern coast of the island. The wood obtained from the Haytian ports

(of the western part of the same island) is much less esteemed in the

London market.

[408] It has been remarkably well pointed out already by Valerius

Cordus (_obiit_ 1544). See Gesner’s edition of his _Hist. Stirpium

Argentorat_., 1561. 191.

[409] See also Oberlin et Schlagdenhauffen, _Journ. de Pharm._ 28

(1878) 246 and plate vi.

[410] That of _Guaiacum arboreum_ DC. is apparently very different.

This tree, occurring in New Granada, has already been noticed

(1571-1577) by Francisco Hernandez (_Nova plantarum, animal, et

mineral. mexicanor. hist._, Romæ 1651, fol. 63) under the name of

_Guayacan_. He mentions its large umbels with yellow flowers, those of

Guaiacum officinale, the “_Hoaxacan_” or Lignum sanctum, being blue. In

the _Prodromus Floræ Neo-Granatentis_ (_Ann. Scienc. nat._ xv., 1872.

p. 361) J. E. Planchon also describes Guaiacum arboreum, known there as

_Guayacan polvillo_; its wood is of an almost pulverulent fracture.

[411] _Consular Reports_ presented to Parliament, Aug. 1872.

Some small wood of good quality comes from the Bahamas, and an ordinary

quality, also small, from Jamaica. From the latter island, the quantity

exported in 1871 was only 14 tons;[412] from the Bahamas in the same

year 199 tons.[413] Lignum Vitæ was shipped from Santa Marta in 1872 to

the extent of 115 tons.[414]

Hamburg is also an important place for the wood under notice; in 1877

there were imported 22,404 centners from S. Domingo and 3551 centners

from Venezuela.

=Uses=—Guaiacum wood is only retained in the pharmacopœia as an

ingredient of the Compound Decoction of Sarsaparilla. It is probably

inert, at least in the manner in which it is now administered.[415]

=Adulteration=—In purchasing guaiacum chips it is necessary to observe

that the non-resinous sapwood is absent, and still more that there is

no admixture of any other wood. A spurious form of the drug seems to be

by no means rare in the United States.[416]

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