HURA.—ASSACÙ.—OASSACÙ.

[Illustration]

This plant inhabits the equatorial regions of South-America, the

provinces of Para, Rio-Negro, and the neighborhood of the Amazon, where

it is very frequent. It resembles the hura crepitans; its leaves are

alternate, somewhat cordate, rounded, glabrous, serrate; rolled up and

stipulate while young. The petiole is provided at its top with two large

glands. Flowers monoïchous; the male flowers having a short, urceolate

perianth, and covered with a scaly bract; they form elongated, peduncled,

terminal husks. The female flowers, which are twice as long as those

of the hura crepitans, have their perianth resting against the ovary,

which is surmounted by a long and infundibiliform style, terminated by a

stellate stigma; they are solitary and placed near the male flowers. It

is from this tree that the Indians draw the milky juice called Assacù by

the Brazilians.

A man affected with lepra, and who had sought refuge in the solitary

regions of the Amazone, took, by the advice of an Indian whom he met

there, a considerable quantity of a juice known under the name of Assacù,

flowing from the trunk of a tree, which has been described by Willdenow,

under the name of hura braziliensis. He was cured; and the president of

the province of Para, informed the imperial government of it. Since then,

this juice has been very generally used by leprous patients without,

however, curing them.

The first and third provers of this drug, on a voyage to Brazil, in

1842, had both been attacked with the lepra. Under homœopathic treatment

they seemed both to have got well, though one might have inferred from

the gravity of their symptoms, that they had been palliated rather than

cured. The frightful symptoms of compression of the spinal marrow, which

supervened in the case of one of the provers, point to the Assacù as a

powerful remedy for various forms of myelitis. The symptoms of nervous

excitement, the twitching, the irritability of the temperament exhibited

by all the provers, favor the doctrine that the lepra is a particular

lesion of the nervous system. If the exanthems and the insensibility

of the skin characteristic of the lepra, have been less marked in our

provings, it is undoubtedly because these phenomena belong to some

chronic form which a continued use of the drug and a real poisoning are

alone capable of producing.

These four provings have been instituted with a single drop of the

fifth attenuation. It is our rule to avoid repeating the dose lest the

chronological succession of the symptoms which we regard as important,

should be disturbed. We do not believe that repeated doses can do much

good, and if a prover should not experience any effects from one dose, we

should prefer dropping this proving, and resort to some other drug, to

which his organism should be more sensible.

First prover: Aug. Joly, 29 years of age, bilious-nervous temperament,

healthy constitution.

_First day._—Took one drop of the 5th attenuation at ten o’clock at night.

1. One hour after, itching at the ribs and sternum, at the biceps and

the posterior parts of the right arm. Doughy mouth, in the morning, on

waking. Dreams about a ball, about houses in process of erection. In

the morning, itching at the arms, legs, outer parts of the tibia. 5. The

upper and lower eyelids are inflamed and blueish. Itching at the right

arm, at the lower and inner portion of the humerus, owing to a little

pimple which is forming. Taste of blood in the mouth. Whizzing in the

ears, especially the right. Clusters of miliary pimples on the back,

arms, legs and chest. 10. Irritated by the least contrariety. Desire

to vomit, sick stomach. Rheumatic pain at the left arm. He looks weary

as if he had been carousing all night, though he slept well all night.

Pinching at the right side of the tongue. 15. Lancination in the canal of

the urethra. Prickling around the eyes, and especially around the right

one. Sensation as if small pimples would break out on the inside of the

eyelids. Nervous beating in the eyelids. Rheumatic pain at the sacrum,

especially when stooping. 20. Contusive pain at the lumbar region.

Miliary eruption in the joints.

_Second day._—Dry mouth in the morning. Acute pain in the lumbar region

and at the sacrum, as from a fall. Smoky taste of the water which is

drank at breakfast. 25. Pain in the ileo-femoral articulation. Pain all

along the left thigh. Sneezing, and frequent blowing, as when a catarrh

is about setting in, followed by involuntary discharge from the nose of

a lemon-colored mucus, with tickling. Constant pain in the lower part

of the lumbar regions, worse when stooping or sitting down. Lancinating

pain at the top of the head. 30. Slight desire to vomit at eleven o’clock

in the morning. Dizziness. He dreams that he was swimming in a river

with warm and dark-green water; afterwards that he was on a plantation

in Brazil, where men drew water from a yellow pond. Moist, intermittent

heat, mounting every fifteen minutes from the feet to the face. Prickling

at the right eye. 35. Sense of heat mounting to the clavicles. (At a

quarter of ten o’clock:) Dry nose, he cannot blow it; with itching at the

interior of the nose.

_Third day._—In the morning, the pain at the sacrum had disappeared. (At

ten o’clock and a half:) The pain at the sacrum returns worse, after

moving a box. Burning at the right index-finger, a red spot extending

from the nail to the second phalanx. Numbness; almost amounting to

insensibility. 40. (At half past twelve:) Pain as from a splinter under

the thumb-nail. In the evening, tickling under the arms and along the

dorsal spine. No sleep at night, frequent waking, feverish agitation.

_Fourth day._—Heat in the hands, in the morning. At two o’clock, a small

vesicular pimple on the back of the left hand; for four hours. 45.

Stiffness in the trapezoid muscle, near its attachment at the occiput.

Pain at the left forearm as from a blow. Small vesicular pimples, and

itching at the ribs, arms, and at every prominent process of the bones.

_Fifth day._—In the morning, the pimples on the arms have almost

disappeared; there remains only a little itching at the sternum. Heat at

the tips of the right fingers. 50. Sensation as if a small portion of the

nail of the right index-finger had become detached. At half past six in

the evening, heat and passing sweat. At half past seven in the evening,

sensation of burning, smarting on the left side of the chin, in the

beard, as from an incipient tetter. Sensation under the masseter muscle,

as from a recent blow on the parotid. At eight o’clock in the evening,

the spot becomes sensible to contact; a small swelling is observed

extending below the zygomatic arch. 55. Sensation at the supinator muscle

of the forearm, as from an incipient tetter. Small pimples on the inner

surface of the lower lip. Stiffness of the trapezoid muscle and the neck.

Prickling as from dust, at the border of the lower lid of the right eye.

60. Itching at the back, legs, arms, at the same time.

_Sixth day._—Fleshy excrescenses on the inner surface of the lips. At

four o’clock, weariness in the legs, in going up-stairs. At eight o’clock

in the evening, painful stiffness of the neck. The pain in the masseter

muscle, which had already decreased in the morning, disappeared entirely

in the evening. Weight in the testicles in walking, at five o’clock in

the evening. 65. Taste of blood in the throat before breakfast.

_Seventh day._—Itching at the right lower eyelid, as if a pimple would

appear. At three o’clock, sensation as of dust in the left eye. Sense of

weight at the eyes, as if they had been strained.

_Eighth day._—No sleep all night. 70. Pressive pain at the cranium. Heat

in the nails of the left hand.

_Ninth day._—Straining sensation in the upper part of the sacrum,

preventing him from standing erect, at noon. Taste of blood in the throat

before breakfast. Sputa mixed with blood. 75. Sense of giving way in

the knee-joint, in going down-stairs, at two o’clock. At four o’clock,

pain in the renal region, which keeps increasing; it decreases at five

o’clock. Prickling in the left eye, and intolerable itching, with nervous

irritation which spreads to the heart, but passes off soon.

_Tenth day._—Prickling in the left eye as from dust. Smarting sensation

in the beard as from a pimple at each hair, at nine o’clock. 80. Burning

sensation at the inner canthus of the right eye, at half past nine in the

evening. The carunculæ lachrymales look inflamed.

_Eleventh day._—Itching at the anterior surface of the tibia, at

night, and smarting sensation as from a tetter. Appearance of a small

red circle, with a small dark-red pimple in the middle; followed by

peeling off. Itching at the hairy scalp, especially behind and in the

mastoid process, as from a tetter. 85. Sensation as if he had torn off a

hang-nail, or as from a splinter in the ring-finger of the left hand. At

ten o’clock, smarting at the bend of the right elbow, on the outside.

_Twelfth day._—Tickling at the left arm, with small vesicular pimples.

Itching in the beard, with small pimples which form a crust under

the chin. Itching and small crusty pimples on the hairy scalp. 90.

Constrictive sensation at the anus; at half past five o’clock.

_Thirteenth day._—Painful sensation at the upper and lateral portions

of the sacrum, as if strained or bruised. Clusters of small miliary

pimples at the bend of the elbow, with redness around the pimples after

scratching them. The pimples cease to be vesicular; other pimples appear

on the insteps. Prickling sensation in the eyes all day, with redness

and smarting at the border of the lids. 95. Sensation as if there were

dust or foreign bodies in the eyes. The right eye is more sensible than

the left. Weariness in the legs, after noon. Pain in the left knee as

from a sprain, with lancinations below the pain.

_Fourteenth day._—Contractive sensation below, and at the right side

of the coccyx. 100. Rheumatic pain at the left side of the neck, the

splenius, complexus and trapezoides muscles.

_Fifteenth day._—Rheumatic pain at the neck, with difficulty of turning

the head to the left side, in the morning. Pain in the head like a

weight on the skull, extending to the mastoid processes. Sense of

loathing with nausea. Oppression at the stomach when standing erect.

105. Pale face, with rings around the eyes and redness at the margin of

the eyelids. Pains in the head like a beating in the sides and at the

vertex, reverberating in the mastoid processes, and extending to the

sterno-mastoid muscles. Sense of constriction in the upper part of the

throat. Yellowish, heavy and frothy expectoration, ever since he took

his drug. The affective sphere is very active. 110. Painful stiffness

of the neck, which prevents one from turning the head to the left side.

Sensation, in closing the eyes, as though the eyelids were cold. Pain

from the occiput to the vertex, with beating, and acute pains.

_Sixteenth day._—Horrid pain in the sacro-lumbar region, at the

articulation of the last lumbar vertebra and sacrum, when attempting

to raise a weight. Pain as when straining a ligament; numb pain in the

left thigh, along the course of the sciatic nerve. 115. Inability to

stoop without experiencing acute pains in the sacro-lumbar region; he

is obliged to lie down. Fainting when trying to sit down, caused by the

violence of the pain at the sacrum; sense of tearing. Nervous spasms,

convulsions, cramps in the calves and toes during the fainting spell.

Sense of shuddering at the rectum. Tickling like worms creeping along

in the rectum. 120. In spite of the pains, he slept pretty well in the

night, from the fifteenth to the sixteenth. Desire to urinate, every

half hour. He urinates a long time. Watery urine, with a greenish tint.

Cramp in the right middle, and ring-finger. 125. Pulse interrupted

for two minutes, ringing in the ears, roaring in the head, beating in

the temples. During and after the fainting-spell disposition to love

everybody, especially those around you. He often thinks of death, but

he is not afraid of dying; he even feels as though he would die without

regret. He reproaches himself with everything bad he has done, even the

least trifles, and considers himself very guilty for having done them.

During the nervous attacks, he thinks of his salvation. The sense of

smell is very acute, he even smells persons at a distance.

_Seventeenth day._—130. The pain at the sacrum seems to decrease, but he

is not yet able to rise from bed, nor stir about in it, he has to remain

lying on the back. He has an appetite, but eats little. A sort of painful

glandular swelling behind the masseter muscle, below the right ear.

Dulness of the head, in front. Sense of oppression at the forehead.

_Eighteenth day._—135. Frequent waking at night. He wakes earlier than

usual. Doughy mouth, in the morning. Foul, bloody sputa, of the color of

chocolate with milk. The pain at the sacrum is feebler, it seems to have

spread over a larger space, rises a little towards the dorsal and lumbar

muscles, and to the dorsal vertebræ. 140. The head, above the eyebrows,

is still somewhat dull. Weakness in the finger-joints and wrists. The

gland at the neck continues painful, with lancinations. Taste of blood in

the throat. Flushes of heat. 145. The breathing is painful, as if there

were a sore in the lumbar region.

_Nineteenth day._—Deep and long sleep. Nosebleed, in the morning. Pimple

at the forehead. Weight above the eyes, he is unable to read long. 150.

Sense of weariness in the arms, though lying down. The pain at the sacrum

decreases; sometimes, however, it rises again to the cervical vertebræ.

Prickling in the eyes. A cluster of pimples breaks out at the wrist, on

the external and inferior surface of the radius; they are vesicular,

(like those which he had after his return from Brazil.) Bloating

sensation in the eyes. 155. Throbbing at the sacrum, without pain. Pale

face, eyes sunken, with redness around the eyelids.

_Twentieth day._—No stool from the sixteenth to the twentieth day. Hard

and difficult stool. The pain at the sacrum is much less, though he

still feels a violent throbbing in this region, but painless. 160. Rose

at eight o’clock, his legs were weak and his head felt heavy; he laid

down again an hour after, with very cold feet. He feels a pain at the

iliac bones, though not all the time. There are fever pimples on the arm,

and the remaining pimples contain a little water which spirts out when

pressed. Sensation in the glutei muscles as if bruised. Full and slow

painless beatings in the sacro-lumbar region.

_Twenty-first day._—165. Restless night, dreams about crime, dead bodies,

children with their heads half cut off, and of others whose heads were

being cut. Pain in the glutei muscles as if bruised, now on the right,

then on the left side. Pain as if bruised at the sacrum, with heat

mounting to the face, at nine o’clock in the morning, shortly after

rising. Cramp in the toes. Beatings in the left temple. 170. Painful

stitch and beating sensation between the shoulder-blades.

_Twenty-second day._—Lascivious dream with emission. Heat mounting to the

face, with oppression of the chest. Acute pain in one of the right toes.

Weight at the sacrum, but less bruising in the glutei muscles; weakness

in the knee joints, with cracking, either in going up or down-stairs,

175. Sensation as if a warm liquid were flowing from a sore in the lumbar

region. Heat mounting to the face, at seven o’clock in the evening.

Weakness of the legs in going up or down-stairs.

_Twenty-third day._—Restless night, heat and sweat all night. Dream about

work, vast business. 180. Dizziness at two o’clock, waves before the

eyes; the sight becomes dim when writing. Sparks and zig-zag movements

before the eyes, when walking or sitting. Weak legs. Weight in the upper

lids. Frontal headache. 185. Pressure at the forehead, with damp coldness

at the feet and hands. The headache extends to eyebrows and eyes.

Short-lasting oppression at the throat, in the region of the tonsils. The

eyes are red, with blue dark margins; face pale, yellow, dull. Less pain

in the renal region; but he is unable to stand any length of time without

experiencing an uneasiness in the stomach which extends to the chest with

oppression. 190. Sclerotica red, inflamed, and the capillaries injected.

Beating pressure at the sclerotica. Weakness of the knee-joint, when

walking or going up and down-stairs. Hiccough four hours after eating.

_Twenty-fourth day._—Restless sleep. 195. Slight prickling pain at the

sacro-lumbar articulation, in going up-stairs. Sense of oppression at the

chest.

_Twenty-fifth day._—Pressure at the forehead. Heat in the sacro-lumbar

region; sense of oppression at the chest, and rush of blood to the

larynx, with suffocative oppression; taste of blood and tearing in the

chest.

_Twenty-sixth day._—Restless sleep. 200. Throbbing and weakness in the

sacro-lumbar region. Nausea while riding in a carriage, before breakfast.

Sense of heat in the renal region, after a long ride in a carriage.

Slight aching pain at the forehead and vertex.

_Twenty-seventh day._—Restless sleep. 205. Beatings in the lumbar region,

with slight pullings or shudderings. Weakness in the lumbar region.

Weakness in the knee-joint; sense as if sprained, after a walk.

_Twenty-eighth day._—Restless sleep, with dreams about work, wild beast

devouring meat in a public slaughter-house. Sense of heat with throbbing

and fatigue in the lumbar region and above the iliac bones. 210.

Paleness, cold hands and feet, with weakness all over while the pains

last.

_Twenty-ninth day._—Dream about revolution, gun-shots, demolition of

some public edifice; he walked among the ruins. Sense of well-being, in

the morning on rising. Doughy mouth every morning, with sputa that has

the color of chocolate with cream, and fœtid smell. Spits blood in the

morning that seems to come deep out of the throat. 215. Swelling of the

left lower gums, over the molar teeth, outside, with toothache in this

region. Small pimples on the right knee, with smarting as from a tetter

and painful itching when touching them; they emit a fluid when pressed

upon; itching at the tibiæ.

_Thirtieth day._—The swelling of the gums continues, but the toothache

is less. The cheek threatens to swell. Taste of blood in the mouth and

throat, very marked, with scratching or tearing sensation when drawing

breath. 220. Headache at two o’clock, as from a nail in the vertex, with

violent toothache, swelling of the gums, after a walk. Beatings in the

left side of the face, extending up to the eye. The feet, and mostly the

whole body are constantly damp and cold, with weakness. Uneasiness at the

stomach. His breakfast does not seem to sit well on his stomach; he eats

with a good appetite, however (from the twenty-fourth day).

_Thirty-first day._—Restless night. Intolerable erections, sexual dreams,

with emissions. 225. Large pimples on the legs, around the root of each

hair. In the evening, large pimples, swollen, like mosquito-bites, with

violent itching, and raw feeling when touched.

_Thirty-second day._—Weakness, with painful stitch in the lumbar region.

Uneasiness in the stomach, every day after the noon-meal. Violent

headache on the left side.

_Thirty-third day._—230. Sense of tearing and spraining in back when

sitting (for one minute). Spitting of blood, with sense of rawness in the

throat and the respiratory passages, after talking. Contractive sensation

on the skin of the forehead. Pimples all over the body, similar to those

above described; suffocative sensation rising to the larynx.

_Thirty-fourth day._—Taste of blood in the mouth during an embrace. 235.

General emaciation. Inability to incline forward; he can only walk by

reclining the trunk backwards; when inclining forward ever so little, he

feels a pulling in the lumbar region and is obliged to straighten himself.

_Thirty-fifth day._—Uneasiness at the stomach from the noon-meal until

four in the afternoon. Irritable mood.

_Thirty-eighth day._—Frequent desire to urinate. 240. Clear urine, after

a return of the pain in the sacro-lumbar region. Tearing sensation in the

renal region; acute pain, with faint feeling and pale face.

_Forty-sixth day._—Cold sweat at night.

_Fifty-fifth day._—Pale, sickly face; rings around the eyes. Red lips.

245. Emaciation. Weakness in the sacro-lumbar region. Dimness of sight,

and prickling in the eyelids. (From this period, he gradually gets

better.)

Second prover: Chr. Dieudonné Joly, twenty-four years old,

sanguine-nervous temperament, robust constitution.

At eight o’clock in the evening, took one dose of assacù of the fifth

attenuation.

_First day._—Contraction of the papillæ on the tongue, immediately. 250.

Heaviness of the head. Acute pain in the right kidney while walking, with

urging to urinate, at nine o’clock in the evening; for two minutes.

_Second day._—In the morning, while walking, pain as if sprained in the

left coxo-femoral articulation, for some moments. Prickling at the margin

of the eyelids, in the day-time. Face looks weary, with rings around the

eyes. 255. Lancinations in the left index and thumb. Dull lancinations in

the right hand. Itching at the left side and calf. Stitch in the right

index-finger at eight o’clock in the evening. Feeling as of sand in the

left eye, at ten o’clock.

_Third day._—260. Nocturnal emission. Sneezing at noon, as when a

catarrh is about setting in. At two o’clock, dark redness and almost

complete insensibility of the sides of the neck in the region of the

sterno-cleido-mastoideus-muscles; he pricks the parts and does not feel

any pain until one hour after.

_Fourth day._—No sleep at night, and drowsy in the day-time. Livid

complexion at noon. 265. At nine o’clock in the evening, itching at the

left eyelids.

_Fifth day._—Violent nosebleed, at seven o’clock in the morning. Stinging

in the ball of the right thumb. Slight pain in the medius of the left

hand.

_Sixth day._—Itching at the margin of the left eyelids. 270. At noon,

pimple at the right lower part of the lower jaw. At ten o’clock in the

evening, in bed, smarting and itching of the puncta lachrymalis and the

left lower eyelid.

_Seventh day._—At two o’clock: Aching pain like a stitch in the side,

under the right lower ribs, for one minute.

_Tenth day._—At three o’clock in the afternoon, slight colic, and nausea.

Dull and heavy head, with weak legs.

_Eleventh day._—275. At eleven o’clock, hypochondria, sadness, despair;

he imagines that he is abandoned by his family.

_Twelfth day._—Fatigue, and weakness of sight.

_Thirteenth day._—Eyes red, with weak sight, he reads with difficulty.

The upper and lower limbs feel weak.

_Fourteenth day._—Eyes weary, sight weak. 280. Short, dull, painful

lancinations in the pectoral muscles, rather internal, without impeding

the breathing.

_Fifteenth day._—Weariness of the eyes, pressure at the superior portion

of the orbits. Headache. At nine o’clock in the evening, lancinating pain

in the biceps and triceps muscles of the arm, similar pain between the

shoulder-blade and the spinal column, in the trapezoid muscle. The throat

feels dry and irritated, compelling one to cough. 285. Dryness of the

glottis; causing a cough as from a cold.

_Sixteenth day._—Itching at the margin of the eyelids.

_Seventeenth day._—Sense of stoppage in the ears; afterwards as if

air-bubbles were passing through the left ear (for two or three seconds).

Small smarting pimples on the lower part of the right leg.

_Twenty-third day._—Diarrhœa.

_Twenty-seventh day._—290. Nocturnal emission. Weight at the frontal

muscle. Heat about the head. Painful stitch in the ileo-cœcal region,

recurring several times when walking or moving about. Slight nausea.

_Thirtieth day._—295. Pain as from weariness in the outer portion of the

left crural muscle when pressing upon it.

_Thirty-first day._—This pain is very marked and continues all day.

_Thirty-second day._—Violent headache in the left side of the head.

_Thirty-third day._—Headache in the side of the head.

_Thirty-fourth day._—In the evening, slight pain in the lumbar muscles as

from weariness.

_Thirty-fifth day._—300. The weariness in the loins continues in the

morning. At 9 o’clock in the evening, slight pain as from weariness, with

an acute lancination in the lumbar region, for one second.

_Thirty-sixth day._—At noon, long-lasting lancinating pain under the left

big toe. A good appetite for some days past.

_Thirty-seventh day._—305. Hard, scanty and difficult stool. Absence

of mind. Not disposed to work. Peevish. Red eyelids. 310. Lazy, weary.

Constant yawning.

_Thirty-eighth day._—Hungry, two hours after a copious meal. Tightness at

the stomach, in the evening.

_Thirty-ninth day._—At five o’clock in the morning, violent sensation

of hunger, with tensive and pressive pain at the stomach; when lying,

the pain extends to the umbilical region. 315. The pain during a walk

continues; pressure after eating; painful sensation of hunger. Acute pain

at the stomach, with constant hunger. Frequent desire to urinate. The

urine deposits a white sediment. At noon, pressive pain at the stomach,

before and after eating. 320. Acute pain, like a stitch, at the anterior

surface of the right lung, which hinders breathing. Absence of mind, he

makes many mistakes, mistakes one month for another, for several days. He

mistakes the street twice. During the last days of the proving, frequent

urination with whitish deposit.

Third prover: Mme. Al. j., 26 years old, sanguine temperament, good

constitution.

_First day._—Took one dose of the 5th attenuation, at 10 o’clock in the

evening.

In the morning on waking, doughy taste in the mouth, and great

drowsiness. 325. She dreams about death, burial. Small painful pimples

on the left side of the tongue. Burning at the stomach. Stiffness at the

nape of the neck. Weakness of the legs and arms. 330. Nausea at two

o’clock. Fever: face of a scarlet-red, hands burning-hot. Depression of

spirits, has no desire to do any thing, nothing pleases him. White spots

on the tongue. Frequent desire to urinate. 335. Feeling of weariness all

over. Sense of pain with heat at the sacrum.

_Second day._—Lancinating pain, zig-zag, in the uterus, at half past six

in the morning. Slight leucorrhœa. Dry cough. 340. Pain in the groin,

compressive sensation as during parturition. Lancination from the lumbar

region to the coccyx.

_Third day._—Restless night, frequent waking. On waking, sense of

weariness, as if strained. Acute pain in the palm of the left hand,

proceeding from the index, and describing a circle extending to the

carpal articulation of the thumb. 345. Very weary, especially the left

leg. At half past 12, third night, writhing colic. Violent diarrhœa

at one o’clock, with pains similar to those which she had experienced

on her return from a voyage to Brazil. Fetid stool, with white little

worms. 350. The diarrhœa continues and is succeeded by a great weakness

of the chest. Violet-colored cheeks. Heat in the cheeks and temples. Red

forehead. Small miliary vesicles on the right cheek, on the middle of the

forehead and on the left cheek. 355. Listless, she attends to things as

if she took no sort of interest in them.

_Fifth day._—Dreams about a church-yard; she placed torches on the

graves. On waking, her face is bloated and scarlet-red. Blotches on the

right cheek, similar to those which she had after her return from a

voyage to Brazil (at this time an enormous crusty tetter commenced in

this way). Intolerable heat at the chest, at two o’clock, violent pain

and burning sensation at the sternum.

_Sixth day._—360. Restless sleep. Nervousness, impatience, at half past

12. Dry heat in the hands.

_Seventh day._—Small vesicular pimple at the right wrist-joint. Marked

feeling of heaviness from the parietal bone to the lower attachment of

the sterno-mastoideus muscle, at the upper side of the sternum. 365. At

two o’clock: the weight, at times, descends to the forehead, with heat.

Small pimple on the right wrist, red at its base, containing a fluid.

_Eighth day._—No sleep. Twisting pain in the left side, or lancinations

around the pelvis; the pain passes off soon and extorts cries from her,

at 9 o’clock in the morning. Burning all over.

_Ninth day._—370. Twisting pain at the scapulo-humeral articulation.

Acute pain under the breast. Half past twelve: the pain at the

scapulo-humeral articulation recurs from time to time with great

violence. Five o’clock in the evening: the pain is constant but less,

always of the same kind. Half past nine: miliary eruption in the face.

375. Small red pimples on the right cheek, smarting on the right cheek,

the eruption first showed itself at 7 o’clock in the morning. Miliary

eruption on the shoulders, with itching, in the evening. Red vesicular

pimples, they break when pressed upon, and discharge a smart stream of

water.

_Tenth day._—Dulness of the head, in the morning, on rising. Red face,

the little pimples are less apparent. 380. Pain at the stomach, as from

hunger, though she is not hungry. She swallows her saliva. She has to eat

to quiet her pain.

_Eleventh day._—Headache, slight beating at the forehead, during a

considerable portion of the night. The headache continues with a

heaviness in the forehead, in the morning.

_Twelfth day._—385. Small pimples on the back, with itching. Nosebleed,

at 8 o’clock. Hard stool for 8 days. Nosebleed, at 10 o’clock.

_Thirteenth day._—390. Restless night, dream about a sea-voyage.

Heaviness of the head, nosebleed on rising. Headache, heaviness with

beating in the forehead, all day. Red pimples on the shoulders, with

pricking when touched. Lancination and pricking in the left little

finger, three or four different times.

_Fourteenth day._—395. Hot and red face. Itching red pimples on the

shoulders.

_Fifteenth day._—Sense as of crumbs in the eyes. Sclerotica red, with

margins around the eyes, red eyelids, red face. Red pimples on the sides

of the hips, smarting.

_Sixteenth day._—400. Sharp pain, followed by an acute lancinating pain

about the heart.

_Seventeenth day._—At eight o’clock in the morning, sharp, lancinating

pain, by fits and starts, at the right side of the sacrum, more or less

violent. Ten o’clock in the evening: wry neck on the right side.

_Eighteenth day._—While slumbering, sensation as if she were hanging

three feet from the ground. Sensation as if she would fall into a ditch.

405. Coldness and heat, alternating at night.

_Nineteenth day._—Acute pain at the left hip, at 9 o’clock in the

morning. The pain recurs at 9 o’clock in the evening, and continues for

several days at the same hour. Pain at the uterus as if compressed. Pain

at the heart, which is at times very sharp, almost unbearable. 410. The

breathing is arrested; this pain makes her very uneasy. Lancinating pain

in the head.

_Twentieth day._—Pain at the left knee, as if sprained.

_Twenty-first day._—Writhing colic, and diarrhœa, five times in the day.

_Twenty-second day._—Restless night. 415. In the evening, pain at the

loins and on each side of the ovary. Violent lancinations with prickling,

afterwards lancinating pain in the vagina; appearance of the menses, but

very slight.

_Twenty-third day._—Pain in the uterus as if a sharp instrument were

thrust in. Lancinating pain above the left breast. Pain at the right

little toe, like an intermittent throbbing, with intolerable prickling,

at half past 10 o’clock in the evening.

_Twenty-fourth day._—420. Sleep disturbed by a violent itching caused by

small pimples on the shoulders. In the morning, the pain of the little

toe returns, but it does not last as long as the day previous. Pain in

the renal region, with sense of weariness in the region of the sacrum.

Cold and heavy pain at the left hip. Painful pricking in the wrist and

along the left hand, between the middle and ring-finger.

_Twenty-fifth day._—425. Prickings and stitch above the left breast,

hindering breathing, whether walking or sitting. Acute pain when drawing

breath.

_Twenty-sixth day._—Sense as if sprained in the left knee and cracking

when walking.

_Twenty-eighth day._—Restless night. Desire to cry. 430. Fever, inability

to close her hand. Sad, vexing thoughts.

_Twenty-ninth day._—Sensation as if floating in the air. No sleep.

Starting in bed. 435. Sensation as if she were falling to the ground.

Lancinating pain under the heart; it continues, more or less feeble. Bad

digestion, the stomach feels yet full since supper.

_Thirtieth day._—Restless night, starting during sleep. Sense of

weariness in the lumbar region, all night. 440. Pain at the sacrum

as from a recent blow, this pain increases until four o’clock in the

evening. Pressure at the sacrum, with weariness in the left thigh.

Heaviness at the sacrum, when sitting. Sensation as if worms were

crawling in the posterior and external portion of the sacrum.

_Thirty-first day._—The pain at the sacrum obliges her to keep bent;

this pain shifts up and down from the sacrum to the left thigh, and is

accompanied by chattering of the teeth, which interrupts the speech, and

by cold hands and feet. 445. Quickly-passing tingling and twisting pain

in the right leg, at three o’clock in the evening, when lying. Twisting

pain extending from the sacrum into the left leg, and obliging her to lie

down. Every paroxysm of pain excites a nervous laugh, with moanings like

those of a sick child. Sensation as if dogs had bitten her where the pain

is felt. Sensation as if she had a plaster at the region of the kidneys.

450. The pain descends along the vastus externus muscle. Mottled face,

in the beginning of the proving it became red, now it is sometimes pale.

She cannot walk, without fearing to fall. No solicitude for the future,

generally speaking; tears with ennui; she thinks of death without fearing

it. The pain at the sacrum is worse when sitting, and obliges her to lie

down.

_Thirty-second day._—455. Sleep during the night, but the pain in the

renal region returns as soon as she rises from bed. The pain is seated

in the sacro-lumbar articulation; it extends to the glutei muscles with

sensation as though she were gnawed by dogs. At times the right thumb

feels numb.

_Thirty-third day._—Pain in the vertebral column. Sense of luxation, with

pain in the glutei muscles, of the same nature as the day previous.

_Thirty-fourth day._—460. Twisting sensation in the groin. Nosebleed,

when lying. Vesicular pimples all over, with red spots as if the skin had

been rubbed. Large blotches on the legs like mosquito-bites. Sensation

in the renal region and buttocks as if gnawed by dogs. 465. Continual

sneezing for two hours.

_Thirty-seventh day._—Sensation in the thighs, as if bitten by dogs. The

pimples increase during an increase of temperature, and leave large red

spots in the renal region and on the hips. Since she had the pains in the

sacrum, she is unable to sleep or rest on the stomach.

_Thirty-eighth day._—Uneasiness, sometimes she cries in the street. 470.

Acute headache, like a circle which rolls quickly over the forehead.

Dizziness. Profuse nosebleed from both nostrils. The nosebleed is

preceded by a smell of blood. Red face, with little pimples between the

skin and flesh. 475. Heat at the face. Sensation as if the skin of the

face were stretched too much. Frequent emission of watery urine. Sense of

coldness in the right-thigh.

_Fortieth day._—480. Dreams about dead bodies, assassins, decayed oxen,

yellow water. Continual nosebleed, especially in the morning. The pains

in the renal region decrease.

_Forty-third day._—Nervous twitching at the left lower eyelid.

_Forty-fifth day._—Flow of sad thoughts; she imagines she will lose

somebody who is dear to her. 485. She cries every moment, and, for

several days past imagines she is seeing the dead person before her eyes.

_Fifty-eighth day._—Painful sensibility of the whole right half of the

head, especially when touching it. Lancinations in the jaws, pain at the

right arm. Impatience, anger; she bites her hands, and gets mad because

her ideas flow too slowly.

Fourth prover: Mlle E. R. 17 years, sanguine temperament, good

constitution. 490. At 8 o’clock in the morning, the ball of the thumb of

each hand is painful. 9 o’clock: her feelings are excited and she cries

a good deal. 10 o’clock: numbness of the right index, every minute. Half

past 10: cold and clammy feet, followed by heat for three hours. Half

past 11: short lancinations in the last two left molares, lower jaw;

numbness in the bend of the right arm. 495. Lancination in the right

index-finger, and especially in the articulation of the last phalanx.

Sensation of a small ball under the left breast; at the same time,

lancination under the left shoulder, for 5 minutes. At noon, large red

spot on the lower part of the left cheek. Half past 12: heat at the face,

for half an hour. Half past 12: small pimples on the left cheek, above

the nose and near the lower lip; they are red, with a small white point

in the middle. 500. At two o’clock, beating in the right index-finger.

At half past 2, lancination in the gums. At a quarter past four; pain in

the gums corresponding to the left eye, with heat in the face. Burning in

the left cheek, weight at the eyes, lancinating pains in the ears. Pain

at the outer ankle, as from a blow. 505. Frontal headache, at half past 9

in the evening. Cold sweat on the face. Pressure in the orbits, as from a

violent headache. The teeth and gums are painful when pressing the teeth

against each other; the pain extends to the nose. Toothache on the left

side.

_Second day._—510. Half past seven, white-coated tongue. Slight pain

shifting from the left ear, where it commenced, to the left orbit.

Small pimple at the inside of the left elbow, causing a smart itching.

Half past 7, lancinations in the right side, every second. Cold feet.

515. Eight o’clock, pain as if the right arm had been stretched a long

time, contusive pain at the back of the right hand, especially at the

middle-finger. Lancinations in the gums on the right side. Itching at

the forehead. Small pimples at the forehead. Suffocative oppression

in the chest, especially when thinking of any thing contrary. 520. The

oppression ascends and immediately after descends again. Heat mounting to

the face. Pain at the sternum. Lancinations in the temples. Pain in the

gums on the left side. 525. Discouraged, does not wish to do any thing.

Weight at the arms. Suffocative oppression in the chest. Ten o’clock in

the evening, pain in the orbits as from a violent headache, or as from

looking fixedly at the same object.

_Third day._—Half past 6 in the morning, the right cheek is quite

swollen, without toothache. 530. Red pimple on the left cheek, in the

middle, and on the left side of the neck, with a good deal of itching.

Nine o’clock, beating at the right side of the thorax, almost under

the shoulder. Half past 3, pain at the right wrist; all the veins and

fibres hurt her. Half past 8, oppression at the stomach. Twisting colic.

535. Nine o’clock, heat at the face. Half past 10, desire to cry. Since

taking the drug, the least thing irritates her; at such times she feels

oppressed, with desire to cry, she blushes, sighs a good deal, several

times a day. Less appetite. Pain at the chest, especially the left

breast, when lying; the pain gradually passes to the right side.

_Fourth day._—540. Since the first day, she wakes sooner than previously;

her sleep was heavy and she was unable to open her eyes. Now she opens

them easily, and the ideas come to her at once. Half past 5, shuddering

all over, she feels oppressed, wants to cry. Colic, with cold feet. Eight

o’clock, the shuddering extends over the legs; she feels oppressed and

has cold feet. 545. Nine o’clock, prickling at the tongue on the left

side, causing a good deal of water to accumulate in her mouth. Nervous

pain shifting speedily from the orbits to the forehead, and disappearing

at once. She sighs a good deal. Ten o’clock, she feels sick at the

stomach, as from hunger, generally she is not hungry till noon. Hungry,

sometimes shortly after a meal. 550. Pain as from pressing strongly on a

sore behind the right ear, and under the neck, at the larynx; pain when

moving the head. Cold feet, at 10 o’clock in the morning. Hunger, with

pain in the stomach, at 11 o’clock. Tightness at the root of the nose,

for an instant. Short lancinations all over the face, with tightness of

the head emanating from the temples. 555. Slight contusive pain under the

false right ribs.

_Fifth day._—At noon, oppression hindering breathing. Oppression in the

chest, causing her to sigh a good deal. Numbness of the head. The face,

and head, from the vertex, pain her horribly. 560. Contusive pain between

the ring- and little finger, only for a moment; reaching up to the elbow.

Tightness at the back of the head. Pain as from weariness in front of and

behind the neck. Frequent desire to urinate. The left cheek is very red.

565. Redness of the wing of the nose. Shuddering along the back and legs

while taking breakfast. At 5 o’clock, oppression and sighs. Pain in the

ear, and half of the jaw, followed by pricking in the ear. At a quarter

past 5 o’clock, colic and shuddering. 570. At 8 o’clock, pain as from

weariness between the shoulders. At 9 o’clock, oppression on the chest.

She sighs a good deal. Internal trembling. Cold sweat on the feet. 575.

At half past 10, red blotch on the right shoulder; hot feet, after lying

down, in bed.

_Sixth day._—At 6 o’clock, colic, with diarrhœa and internal trembling.

Shuddering at half past 6. Red spot and itching at the forearm. At 7

o’clock, colic with diarrhœa and shuddering. 580. Nervous laughter

which causes her to shudder. Cold feet, shuddering in the left leg.

At 8 o’clock, cracking in the right forearm. Lancination in the left

gums, reaching to the right ear. At a quarter past 8, red spot like a

flea bite, on the back of the left hand. 585. Dulness of the head, with

weight at the orbits. Cold feet, especially the left. At 9 o’clock,

oppression on the chest, with sighing. At 11 o’clock, weight at the

orbits, as from sleep. Crampy pain at the right wrist, shifting to

the arm and then to the axilla. 590. Colic at the stomach. Oppression

and sighing. Trembling of the right arm, and beating at the anterior

surface of the wrist. At a quarter past 11, rheumatic pain at the right

shoulder. Small vesicular pimples on the lower lip, itching a good

deal. 595. Pain as from having been lying in a wrong position, under

the arm, under the right sight side of the chest. Painful beating above

the right breast. Painful lancinations in the head, striking to the ear

and the left teeth, and then shifting to the upper part of the orbit.

Drowsy at noon. Pain between the shoulders, worse by pressing against the

sternum. 600. Contusive pain at the left leg. Painful stitch at the outer

breast, extending under the arm. Hungry, but satiated at once. Itching

at the right outer ankle. Numbness of the right arm, as far as the left

index-finger, all the muscles hurt him. 605. At one o’clock, formication

in the soles of the feet. At half past one, contusive pain in the back,

at the hips and in the renal region. Strong pressure at the left temple.

Drowsy at 2 o’clock. Colic at half past 3. 610. At 4, beating at the

outer side of the right wrist. Nervous shuddering all through the chest,

and passing between the shoulders. Lancination from the left side of the

head to the eye, temples, above the ear and in the lower jaw. Whizzing

in the ears. Pain at the stomach as from hunger. 615. Lancination in the

left breast. Lancination in the first phalanx of the middle-finger. At

4, toothache on the left side, affecting the eyes. Violent pain in the

back as if weary, and affecting the lumbar region. Pain at the stomach,

oppression, sighs. 620. Lancination in the left gums. At 4, beating in

the right external ankle. Lancination in the whole jaw. Redness, and heat

mounting to the face; cheeks and forehead are redder than the rest of the

face. At half past 8, oppression, pain at the stomach, as from hunger.

_Seventh day._—625. At 6, colic, diarrhœa and shuddering. At 8, merry,

with desire to laugh, followed by shuddering in the head and legs.

Cold feet. Lancination in the left lower gums, tightness of the nose,

felt even in the jaw. Feelings excited, oppressed, as from some great

misfortune. 630. Nervous pain below the bend of the right elbow,

descending to the ring- and little fingers, at 10 in the morning. Painful

pressure on the left shoulder, which is very sensitive, at 11 in the

morning. Beating at the right shoulder. At 11, lancination in the gums

and left eye. Stiff neck, the least motion causes a pain in the nape of

the neck and gums. 635. Weight at the eyes and in the head. Numbness at

the nape of the neck. Sensation as of a bar through the jaws, from ear

to ear, with tightness of the head. Tightness at the root of the nose.

640. The teeth are painful when chewing. Pain in the back, under the

right shoulder, accompanied by beatings in the chest. Cold feet at one

o’clock. Beatings in the right side of the chest. Heat in the face and

drowsy after dinner. 645. Weight at the orbits. Pain in the side, with

lancinations in the right breast. Pain in the bend of the right elbow,

worse when moving it. Beating at the lip of the right index-finger.

Suffocative oppression, causing her to sigh a good deal. 650. Colic,

yawning. Beatings at the tip of the tongue, on the left side. At half

past 2, pain in the renal region when sitting. Heat and pain in all the

toes. Numb pain from the wrist to the upper part of the right arm. 655.

Stiffness and beating in the left side of the neck, especially when

moving the head. At half past 8 in the evening, beating in the right

orbit, afterwards in the sides. Beating at the root of the nose. Painful

stitches in the right side, hindering breathing. At a quarter past 10,

aching and contusive pain in the right side. 660. Pain as from weariness

below the right shoulder. Head heavy and dull, the least motion affects

her eyes and the region of the orbits. Lancinations in the gums and heat

in the face.

_Eighth day._—At 6, colic and diarrhœa. Lancination in the left breast,

at 2 in the evening. 665. Pain in the right renal region. At noon, pimple

on the forehead, left side. At 2, heat in the face. At 4, beating in the

right, and sometimes left orbit. At 6, painful stitch in the right side,

hindering breathing. 670. At 7, sadness, desire to weep. Rush of blood

to the head. Heat in the face. At 10, nosebleed. At 11, cold and clammy

feet, while lying down. 675. Hot feet, some time after.

_Ninth day._—At 6, pain in the right thigh, high up, at the outer side,

causing her to limp. Painful stitch in the left breast. At half past 7,

desire to weep, oppression as from some emotion. At half past 8, desire

to weep, the least trifle makes her sad; she starts when hearing a

door opened suddenly. 680. She is oppressed and breathes heavily. Pain

in the right wrist, striking to each finger. Hot face. Great desire to

weep, even while singing, followed by oppression, at half past 9 in the

morning; she weeps. Acute nervous pain from the shoulder to the left

breast. 685. Pain at the bend of the right elbow. Heaviness in the eyes

and desire to sleep, at a quarter of one. Beating in the left side of the

abdomen. Beating in the pit of the stomach, reverberating in the whole

chest. Frequent ineffectual urging to stool. 690. Tight pain above the

ears, with numbness of the jaw. Heaviness in the whole head. Lancination

in the left lower gums; shortly after, lancination in the upper gums.

Stiffness of the nape of the neck. Hot face. 695. Loud whizzing in the

left ear. Drowsy. Numbness of the gums. Deep sighing, yawning. Mounting

of heat to the face, now and then. 700. Pain in the left gums striking

to the eye and behind the ear. At one o’clock, heat, no appetite.

Lancinations in the gums, reverberating in the whole head. Violent

beating at the left temple. Numbness of the left wrist, the whole hand

is painful. 705. Acute pain in the left gums, the whole left side of the

head is numb. Warm hands and cold sweat, at 3 in the afternoon.

_Tenth day._—Torpor of the head, with numbness in the upper gums and the

muscles of the eye. Pain at the right hip, at one o’clock. Tightness

at the epigastrium; her feelings are very much excited, as if some

misfortune should happen to her, at 2 in the afternoon. 710. Pain in the

right ear. Pain in the left cheek and gums. Beating in the arm and right

wrist. Weight at the right orbit, at 3. Little appetite. 715. Cold sweat

in the face, at half past 6. Suffocative oppression. Drowsy, at half past

8. Hot face, at 9.

_Eleventh day._—Restless sleep. 720. Doughy mouth, at 6 in the morning.

Inflammation of the left puncta lacrymalis. Pain at the right gums and

cheek, at noon. Burning of the cheeks, from one to four.

_Twelfth day._—Small pimples in the face, at 6 in the morning. 725.

Pain in the renal regions, at 9. Weakness of the legs. Beating under

the right hip. Pain at the gums, at 11. At 2 in the afternoon, pain and

beating under the left shoulder. 730. At 8, small pimples on the chin,

itching a good deal. At half past 8 in the evening, colic and cold sweat.

_Thirteenth day._—Eyes bloated, surrounded by margins. Colic and

diarrhœa. Uneasiness when lying down. 735. Leucorrhœa. The period sets in

8 days before its time. Profuse menses. At half past 6, lancination in

the left gums. At 7, lancinations in the jaw. 740. Tightness at the root

of the nose. Numbness of the right arm. At 9, whizzing in the right ear.

Pain and beating on the right shoulder. At 10, beating in the left little

finger, thumb and index-finger. 745. Burning at the whole hand. Violent

itching at the index-finger, the whole of the left arm is painful,

especially the wrist joint. At half past 10, beating pain near the right

internal ankle. Hot feet. Toothache, on the left side. 750. At 11, pain

and itching at the left foot, violent pain in the whole of the right

foot. Violent pain near the inner canthus of the left eye. Pain in the

left wrist-joint. Beating in the right index-finger. At noon, bloating of

the lower eyelids. 755. Redness on the left side of the nose. Pain in the

wrist and bend of the left arm. Contusive pain at the right knee. Pain in

the left gums. Pain in the legs as from weariness. 760. At 2, lancinating

pain shifting from the knees to the right elbow, then to the shoulder,

to the right foot, right wrist, and lastly to the knees. At half past

2, nervous pain in the renal region. Pain behind and in the right ear.

Colic. Pain in the left gums, striking to the root of the nose. 765.

Pain in the left wrist. Pain as from weariness in the back, near the

left shoulder. Whizzing in the right ear. Pain as if her arm were pulled

violently. Painful stiffness in the left side of the neck.

_Fourteenth day._—770. At half past 6, pain in the wrist. Pain behind the

head and in the neck, reverberating in the left gums. Stiff neck. Pain

and beating in the elbow, at the right forearm and in the bend of the

left elbow. Rheumatic pain in the right shoulder, passing under the arm.

775. Painful stitch in the left breast. At noon, the left foot burns,

the right foot is cold. Heat and pain at the right index-finger. At half

past one, heat at the feet, especially the right foot. Pain at the right

little toe. 780. At 2, pain at the tip of the tongue. At 10, pain in the

left gums.

_Fifteenth day._—At 10 in the morning, pain at the gums. Suffocative

oppression of the chest. At 9 in the evening, nervous trembling of the

right arm.

_Sixteenth day._—785. At noon, beating at the right middle and

index-finger.

_Seventeenth day._—Dreams about purchases. At half past 9, pain at the

right arm, shifting to the little finger. Pain at the left breast, almost

under the shoulder. Numbness of the right wrist. 790. Beating at the

right shoulder. Lancination in the left gums. At half past 10, pain in

the whole right hand. Pain in the right orbit. Pain at the left wrist and

in the whole hand. 795. Pain in extending the left arm. At noon, nervous

shuddering. Burning pain with red spot above the right elbow. Nervous

pain shifting from the eye to the gums, with beating at the left temple.

Violent beating in the left side of the thorax, under the shoulder. 800.

Heaviness at the left orbit. Lancinations in the right wrist and thumb.

Drowsy, at 2. Numbness of the arm. At 3, pain in the back and chest. 805.

Beating at the right temple. Violent pain like a stitch, in the left

breast. At 2, slight itching at the knee, below the lower lip, changing

to an acute pain when rubbed, which lasts all day.

_Eighteenth day._—Dreams about mutilated bodies, dead bodies, with the

arms cut off. At half past 6, pain under the lower lip, with swelling on

the left side, and a large red pimple in the centre of the swelling. 810.

At 8, pain and prickling at the right shoulder. Beating above the right

knee. At 5, cold feet, hot face.

_Nineteenth day._—Dreams about children, prisoners being set free. At

half past 8, cold feet. 815. At 3, pain in the orbits and forehead. At

half past 4, pain at the gums passing to the left eye. Pain at the right

wrist, between the thumb and index-finger, also near the bend of the

arm. Nervous beating in the left orbit. The skin on the forehead feels

stretched. 820. Impatient; she wants to break every thing. Absence of

mind at work. She imagines she is alone in the world and lost. Weeping

without cause, followed by nervous laugh. Sad, melancholy; she thinks of

the future, feels unhappy.

_Twentieth day._—825. At one o’clock in the afternoon, sickness at the

stomach after eating. Hemicrania, pains all through the head. Drowsy,

with nausea. Tightness of the back part of the head. Sharp pain behind

the ears. 830. The least thing hurts her, causing horrible pains in the

forehead, temples and under the chin. Lancination behind the neck, on the

left side. Beating in the left breast. Cold feet. At 5, shuddering all

the time. 835. Headache when walking. Horrible pain and beating in the

chest. Involuntary closing of the eyelids. Pain in the gums. Internal

trembling. 840. Rush of blood to the head; she turns red.

_Twenty-first day._—From the 11th to the 21st day, profuse menses with

leucorrhœa. At half past 2, pain and beating in the left shoulder. At 3,

beating in the left side of the head. Drowsy: heaviness of the head.

_Twenty-second day._—845. No sleep. Colic with diarrhœa, from the 18th

day. Heaviness of the head. From the 23d to the 28th day, horrible colic,

every morning, with diarrhœa, and pains in the middle of the back.

Nervous, she starts when a chair is moved with a little noise. 850. She

turns red, and her chest feels oppressed. Every day, after breakfast,

she has an attack of oppression on the chest. Difficult digestion after

breakfast; after noon she turns pale.

_Thirty-third day._—She feels hot at the hands, feet and face, though the

hands are cold and clammy to contact; she thinks this is likewise the

case with her feet and face. Cold sweat on the face and body.

_Thirty-fourth day._—855. The eyes are bloated and smaller. Painful

pimples when touched, on the left cheek and at the eyebrows.

_Thirty-fifth day._—Starting from the least noise. Yawns all the evening.

_Thirty-eighth day._—Violent pain in the chest, shifting to the left

breast, sometimes to the right, especially when moving the arm. 860.

Headache.

_Thirty-ninth day._—Pain and sense of weariness in the renal region.

Dreams about travelling and parties. Drowsy at one in the afternoon.

Hot face. 865. Coryza. Face dull and dark, with paleness, mottled with

red spots. Pain in the renal region, as from falling on the sacrum.

Copper taste in the mouth. Pain in left side hindering breathing. 870.

Inflammation of the right eye.

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