After some hours this pain occasioned by the torpor of the vessels of the

cheek either gradually ceases along with the pain of the diseased tooth;

or, by the accumulation of sensorial power during their state of torpor,

the capillaries of the cheek act with greater violence, and produce more

secretions, and heat, and consequent tumour, and inflammation. In this

state the pain of the diseased tooth ceases; as the sensorial power of

sensation is now expended on the inflamed vessels of the cheek. It is

probable that most other internal membranous inflammations begin in a

similar manner; whence there may seem to be a double kind of sensitive

association; first, with decreased action of the associated organ, and then

with increased action of it; but the latter is in this case simply the

consequence of the former; that is, the tumor or inflammation of the cheek

is in consequence of its previous quiescence or torpor.

2. _Stranguria a dolore vesicae._ The strangury, which has its origin from

pain at the neck of the bladder, consists of a pain in the external

extremity of the urethra or of the glans penis of men, and probably in the

external termination of the urethra or of the clitoris of women; and is

owing to the sympathy of these with some distant parts, generally with the

other end of the urethra; an endeavour and difficulty of making water

attends this pain.

Its remote cause is from the internal or external use of cantharides, which

stimulate the neck of the bladder; or from a stone, which whenever it is

pushed into the neck of the bladder, gives this pain of strangury, but not

at other times; and hence it is felt most severely in this case after

having made water.

The sensations or sensitive motions of the glans penis, and of the

sphincter of the bladder, have been accustomed to exist together during the

discharge of the urine; and hence the two ends of the urethra sympathize by

association. When there is a stone at the neck of the bladder, which is not

so large or rough as to inflame the part, the sphincter of the bladder

becomes stimulated into pain; but as the glans penis is for the purposes of

copulation more sensitive than the sphincter of the bladder, as soon as it

becomes affected with pain by the association above mentioned, the

sensation at the neck of the bladder ceases; and then the pain of the glans

penis would seem to be associated with the irritative motions only of the

sphincter of the bladder, and not with the sensitive ones of it. But a

circumstance similar to this occurs in epileptic fits, which at first are

induced by disagreeable sensation, and afterwards seem to occur without

previous pain, from the suddenness in which they follow and relieve the

pain, which occasioned them. From this analogy I imagine the pain of the

glans penis is associated with the pain of the sphincter of the bladder;

but that _as soon as the greater pain in a more sensible part is produced;

the lesser one, which occasioned it, ceases_; and that this is one of the

laws of sensitive association. See Sect. XXXV. 2. 1.

A young man had by an accident swallowed a large spoonful or more of

tincture of cantharides; as soon as he began to feel the pain of strangury,

he was advised to drink large quantities of warmish water; to which, as

soon as it could be got, some gum arabic was added. In an hour or two he

drank by intervals of a few minutes about two gallons of water, and

discharged his urine every four or five minutes. A little blood was voided

towards the end, but he suffered no ill consequence.

M. M. Warm water internally. Clysters of warm water. Fomentation. Opium.

Solution of fixed alkali supersaturated with carbonic acid. A bougie may be

used to push back a stone into the bladder. See Class I. 1. 3. 10.

3. _Stranguria convulsiva._ The convulsive strangury, like that before

described, is probably occasioned by the torpor or defective action of the

painful part in consequence of the too great expenditure of sensorial power

on the primary link of the associated motions, as no heat or inflammation

attends this violent pain. This kind of strangury recurs by stated periods,

and sometimes arises to so great a degree, that convulsion or temporary

madness terminates each period of it. It affects women oftener than men, is

attended with cold extremities without fever, and is distinguished from the

stone of the bladder by the regularity of its periods, and by the pain

being not increased after making water.

On introducing the catheter sometimes part of the urine will come away and

not the whole, which is difficult to explain; but may arise from the

weakness of the muscular fibres of the bladder; which are not liable

suddenly to contract themselves so far as to exclude the whole of the

urine. In some old people, who have experienced a long retention of urine,

the bladder never regains the power of completely emptying itself; and many

who are beginning to be weak from age can make water a second time, a few

minutes after they supposed they had emptied the bladder.

I have believed this pain to originate from sympathy with some distant

part, as from ascarides in the rectum, or from piles in women; or from

caruncles in the urethra about the caput gallinaginis in men; and that the

pain has been in the glans or clitoris by reverse sympathy of these more

sensible parts with those above mentioned.

M. M. Venesection. Opium in large quantities. Warm bath. Balsams. Bark.

Tincture of cantharides. Bougie, and the treatment for haemorrhoids.

Leeches applied to the sphincter ani. Aerated alcaline water. Soap and sal

soda. Opium in clysters given an hour before the expected return. Smoke of

tobacco in clysters. Arsenic?

4. _Dolor termini intestinalis ductus choledochi._ Pain at the intestinal

end of the gall-duct. When a gall-stone is protruded from the gall-bladder

a little way into the end of the gall-duct, the pain is felt at the other

end of the gall-duct, which terminates in the duodenum. For the actions of

the two terminations of this canal are associated together from the same

streams of bile passing through them in succession, exactly as the two

terminations of the urethra have their actions associated, as described in

Species 2 and 3 of this genus. But as the intestinal termination of the

bile-duct is made more sensible for the purpose of bringing down more bile,

when it is stimulated by new supplies of food from the stomach, it falls

into violent pain from association; and then the pain on the region of the

gall-bladder ceases, exactly as above explained in the account of the pain

of the glans penis from a stone in the sphincter of the bladder.

The common bile-duct opens into the intestine exactly at what is called the

pit of the stomach; and hence it has sometimes happened, that this pain

from association with the sensation of a gall-stone at the other end of the

bile-duct has been mistaken for a pain of the stomach.

For the method of cure see Class I. 1. 3. 8. to which should be added the

use of strong electric shocks passed through the bile-duct from the pit of

the stomach to the back, and from one side to the other. A case of the good

effect of electricity in the jaundice is related in Sect. XXX. 2. And

another case, where it promoted the passage of a painful gall-stone, is

described by Dr. Hall, experienced on himself. Trans. of the College at

Philadelphia, Vol. I. p. 192.

Half a pint of warm water two or three times a day is much recommended to

dilute the inspissated bile.

5. _Dolor pharyngis ab acido gastrico._ The two ends of the throat

sympathize by sensitive association in the same manner as the other canals

above mentioned, namely, the urethra and the bile-duct; hence when too

great acidity of undigested aliment, or the carbonic acid air, which

escapes in fermentation, stimulates the cardia ventriculi, or lower end of

the gula, into pain; the pharinx, or upper end of it, is affected with

greater pain, or a disagreeable sensation of heat.

6. _Pruritus narium a vermibus._ The itching of the nose from worms in the

intestines is another curious instance of the sensitive associations of the

motions of membranes; especially of those which constitute the canals of

the body. Previous to the deglutition of agreeable food, as milk in our

earliest infancy, an agreeable odour affects the membrane, which lines the

nostrils; and hence an association seems to take place between the

agreeable sensations produced by food in the stomach and bowels, and the

agreeable sensations of the nostrils. The existence of ascarides in the

rectum I believe produces this itching of the nostrils more than the worms

in other parts of the intestines; as we have already seen, that the

terminations of canals sympathize more than their other parts, as in the

urethra and gall-ducts. See Class I. 1. 5. 9. IV. 1. 2. 9.

7. _Cephalaea._ Head-ach. In cold fits of the ague, the head-ach arises

from consent with some torpid viscus, like the pain of the loins. After

drunkenness the head-ach is very common, owing to direct sympathy of the

membranes of the head with those of the stomach; which is become torpid

after the too violent stimulus of the preceding intoxication; and is hence

removeable by spirit of wine, or opium, exhibited in smaller quantities. In

some constitutions these head-achs are induced, when the feet are exposed

to much external cold; in this case the feet should be covered with oiled

silk, which prevents the evaporation of the perspirable matter, and thence

diminishes one cause of external cold.

M. M. Valerian in powder two drams three or four times a day is

recommended. The bark. Chalybeates. A grain of opium twice a day for a long

time. From five to ten drops of the saturated solution of arsenic two or

three times a day. See Class I. 2. 4. 11. A lady once assured me, that when

her head-ach was coming on, she drank three pints (pounds) of hot water, as

hastily as she could; which prevented the progress of the disease. A

solution of arsenic is recommended by Dr. Fowler of York. Very strong

errhines are said sometimes to cure head-achs taken at the times the pain

recurs, till a few drops of blood issue from the nostrils. As one grain of

turpeth mineral (vitriolic calx of mercury) mixed with ten grains of fine

sugar. Euphorbium or cayan pepper mixed with sugar, and used with caution

as an errhine. See the M. M. of the next Species.

8. _Hemicrania._ Pain on one side of the head. This disease is attended

with cold skin, and hence whatever may be the remote cause, the immediate

one seems to be want of stimulus, either of heat or distention, or of some

other unknown stimulus in the painful part; or in those, with which it is

associated. The membranes in their natural state are only irritable by

distention; in their diseased state, they are sensible like muscular

fibres. Hence a diseased tooth may render the neighbouring membranes

sensible, and is frequently the cause of this disease.

Sometimes the stomach is torpid along with the pained membrane of the head;

and then sickness and inappetency attends either as a cause or consequence.

The natural cure of hemicrania is the accumulation of sensorial power

during the rest or sickness of the patient. Mrs. ---- is frequently liable

to hemicrania with sickness, which is probably owing to a diseased tooth;

the paroxysm occurs irregularly, but always after some previous fatigue, or

other cause of debility. She lies in bed, sick, and without taking any

solid food, and very little of fluids, and those of the aqueous kind, and,

after about 48 or 50 hours, rises free from complaint. Similar to this is

the recovery from cold paroxysms of fever, from the torpor occasioned by

fear, and from syncope; which are all owing to the accumulation of

sensorial power during the inactivity of the system. Hence it appears,

that, though when the sensorial power of volition is much exhausted by

fatigue, it can be restored by eight or ten hours of sleep; yet, when the

sensorial power of irritation is exhausted by fatigue, that it requires two

whole solar or lunar days of rest, before it can be restored.

The late Dr. Monro asserted in his lectures, that he cured the hemicrania,

or megrim, by a strong vomit, and a brisk purge immediately after it. This

method succeeds best if opium and the bark are given in due quantity after

the operation of the cathartic; and with still more certainty, if bleeding

in small quantity is premised, where the pulse will admit of it. See Sect.

XXXV. 2. 1.

The pain generally affects one eye, and spreads a little way on that side

of the nose, and may sometimes be relieved by pressing or cutting the

nerve, where it passes into the bone of the orbit above the eye. When it

affects a small defined part on the parietal bone on one side, it is

generally termed Clavus hystericus, and is always I believe owing to a

diseased dens molaris. The tendons of the muscles, which serve the office

of mastication, have been extended into pain at the same time, that the

membranous coverings of the roots of the teeth have been compressed into

pain, during the biting or mastication of hard bodies. Hence when the

membranes, which cover the roots of the teeth, become affected with pain by

a beginning decay, or perhaps by the torpor or coldness of the dying part

of the tooth, the tendons and membranous fascia of the muscles about the

same side of the head become affected with violent pain by their sensitive

associations: and as soon as this associated pain takes place, the pain of

the tooth entirely ceases, as explained in the second species of this

genus.

A remarkable circumstance attends this kind of hemicrania, viz. that it

recurs by periods like those of intermittent fevers, as explained in the

Section on Catenation of Motions; these periods sometimes correspond with

alternate lunar or solar days like tertian agues, and that even when a

decaying tooth is evidently the cause; which has been evinced by the cure

of the disease by extracting the tooth. At other times they observe the

monthly lunations, and seem to be induced by the debility, which attends

menstruation.

The dens sapientiae, or last tooth of the upper jaw, frequently decays

first, and gives hemicrania over the eye on the same side. The first or

second grinder in the under-jaw is liable to give violent pain about the

middle of the parietal bone, or side of the head, on the same side, which

is generally called the Clavus hystericus, of which an instructive case is

related in Sect. XXXV. 2. 1.

M. M. Detect and extract the diseased tooth. Cut the affected nerve, or

stimulate the diseased membrane by acu-puncture. Venesection to six ounces

by the lancet or by leeches. A strong emetic and a subsequent cathartic;

and then an opiate and the bark. Pass small electric shocks through the

pained membrane, and through the teeth on the same side. Apply vitriolic

ether externally, and a grain of opium with camphor internally, to the

cheek on the affected side, where a diseased tooth may be suspected. Foment

the head with warm vinegar. Drink two large spoonfuls of vinegar. Stimulate

the gums of the suspected teeth by oil of cloves, by opium. See Class I. 1.

4. 4. Snuff volatile spirit of vinegar up the nostrils. Lastly, in

permanent head-achs, as in permanent vertigo, I have seen good effect by

the use of mercurial ointment rubbed on the shaved head or about the

throat, till a mild salivation commences, which by inflaming the membranes

of the teeth may prevent their irritative sympathy with those of the

cranium. Thus by inflaming the tendon, which is the cause of locked jaw,

and probably by inflaming the wound, which is the cause of hydrophobia,

those diseases may be cured, by disuniting the irritative sympathy between

those parts, which may not possess any sensitive sympathy. This idea is

well worth our attention.

_Otalgia._ Ear-ach is another disease occasioned by the sympathy of the

membranes of the ear with those which invest or surround a decaying tooth,

as I have had frequent reason to believe; and is frequently relieved by

filling the ear with tincture of opium. See Class I. 2. 4.

9. _Dolor humeri in hepatitide._ In the efforts of excluding the faeces and

urine the muscles of the shoulders are exerted to compress the air in the

lungs, that the diaphragm may be pressed down. Hence the distention of the

tendons or fibres of these muscles is associated with the distention of the

tendons or fibres of the diaphragm; and when the latter are pained by the

enlargement or heat of the inflamed liver, the former sympathize with them.

Sometimes but one shoulder is affected, sometimes both; it is probable that

many other pains, which are termed rheumatic, have a similar origin, viz.

from sensitive associations.

As no inflammation is produced in consequence of this pain of the shoulder,

it seems to be owing to inaction of the membranous part from defect of the

sensorial power of association, of which the primary link is the inflamed

membrane of the liver; which now expends so much of the sensorial power in

general by its increased action, that the membranes about the shoulder,

which are links of association with it, become deprived of their usual

share, and consequently fall into torpor.

10. _Torpor pedum in eruptione variolarum._ At the commencement of the

eruption of the small-pox, when the face and breast of children are very

hot, their extremities are frequently cold. This I ascribe to sensitive

association between the different parts of the skin; whence when a part

acts too violently, the other part is liable to act too weakly; and the

skin of the face being affected first in the eruption of the small-pox, the

skin of the feet becomes cold in consequence by reverse sympathy.

M. M. Cover the feet with flannel, and expose the face and bosom to cool

air, which in a very short time both warms the feet and cools the face; and

hence what is erroneously called a rash, but which is probably a too hasty

eruption of the small-pox, disappears; and afterwards fewer and more

distinct eruptions of the small-pox supervene.

11. _Testium dolor nephriticus._ The pain and retraction of the testicle on

the same side, when there is a stone in the ureter, is to be ascribed to

sensitive association; whether the connecting cause be a branch of the same

nerve, or from membranes, which have been frequently affected at the same

time.

12. _Dolor digiti minimi sympatheticus._ When any one accidentally strikes

his elbow against any hard body, a tingling pain runs down to the little

finger end. This is owing to sensitive association of motions by means of

the same branch of a nerve, as in hemicrania from a decaying tooth the pain

is owing to the sensitive association of tendons or membranes.

13. _Dolor brachii in hydrope pectoris._ The pain in the left arm which

attends some dropsies of the chest, is explained in Sect. XXIX. 5. 2. 10.

which resembles the pain of the little finger from a percussion of the

nerve at the elbow in the preceding article. A numbness of this kind is

produced over the whole leg, when the crural nerve is much compressed by

sitting for a time with one leg crossed over the other.

Mr. ----, about sixty, had for two years been affected with difficulty of

respiration on any exertion, with pain about the sternum, and of his left

arm; which last was more considerable than is usual in dropsy of the chest;

some months ago the pain of his arm, after walking a mile or two, became

excessive, with coldness and numbness; and on the next day the back of the

hand, and a part of the arm swelled, and became inflamed, which relieved

the pain; and was taken for the gout, and continued several days. He after

some months became dropsical both in respect to his chest and limbs, and

was six or seven times perfectly relieved by one dram of saturated tincture

of digitalis, taken two or three times a day for a few days in a glass of

peppermint water. He afterwards breathed oxygen gas undiluted, in the

quantity of six or eight gallons a day for three or four weeks without any

effect, and sunk at length from general debility.

In this instructive case I imagine the pressure or stimulus of one part of

the nerve within the chest caused the other part, which serves the arm, to

become torpid, and consequently cold by sympathy; and that the inflammation

was the consequence of the previous torpor and coldness of the arm, in the

same manner as the swelling and inflammation of the cheek in tooth-ach, in

the first species of this genus; and that many rheumatic inflammations are

thus produced by sympathy with some distant part.

14. _Diarrhoea a dentitione._ The diarrhoea, which frequently attends

dentition, is the consequence of indigestion; the aliment acquires chemical

changes, and by its acidity acts as a cathartic; and changes the yellow

bile into green, which is evacuated along with indigested parts of the

coagulum of milk. The indigestion is owing to the torpor of the stomach and

intestines caused by their association with the membranes of the gums,

which are now stimulated into great exertion with pain; both which

contribute to expend the general quantity of sensorial power, which belongs

to this membranous association; and thus the stomach and intestines act

with less than their natural energy. This is generally esteemed a

favourable symptom in difficult dentition, as the pain of the alveolar

membranes exhausts the sensorial power without producing convulsions for

its relief. See Class I. 1. 4. 5. And the diarrhoea ceases, as the tooth

advances.

* * * * *

ORDO II.

_Decreased Associate Motions._

GENUS III.

_Catenated with Voluntary Motions._

SPECIES.

1. _Titubatio linguae._ Impediment of speech is owing to the associations

of the motions of the organs of speech being interrupted or dissevered by

ill-employed sensation or sensitive motions, as by awe, bashfulness,

ambition of shining, or fear of not succeeding, and the person uses

voluntary efforts in vain to regain the broken associations, as explained

in Sect. XVII. 1. 10. and XVII. 2. 10.

The broken association is generally between the first consonant and the

succeeding vowel; as in endeavouring to pronounce the word parable, the p

is voluntarily repeated again and again, but the remainder of the word does

not follow, because the association between it and the next vowel is

dissevered.

M. M. The art of curing this defect is to cause the stammerer to repeat the

word, which he finds difficult to speak, eight or ten times without the

initial letter, in a strong voice, or with an aspirate before it, as

arable, or harable; and at length to speak it very softly with the initial

letter p, parable. This should be practised for weeks or months upon every

word, which the stammerer hesitates in pronouncing. To this should be added

much commerce with mankind, in order to acquire a carelessness about the

opinions of others.

2. _Chorea St. Viti._ In the St. Vitus's dance the patient can at any time

lie still in bed, which shews the motions not to be convulsive; and he can

at different times voluntarily exert every muscle of his body; which

evinces, that they are not paralytic. In this disease the principal muscle

in any designed motion obeys the will; but those muscles, whose motions

were associated with the principal one, do not act; as their association is

dissevered, and thus the arm or leg is drawn outward, or inward, or

backward, instead of upward or forward, with various gesticulations exactly

resembling the impediment of speech.

This disease is frequently left after the itch has been too hastily cured.

See Convulsio dolorifica, Class III. 1. 1. 6. A girl about eighteen, after

wearing a mercurial girdle to cure the itch, acquired the Chorea St. Viti

in so universal a manner, that her speech became affected as well as her

limbs; and there was evidently a disunion of the common trains of ideas; as

the itch was still among the younger children of the family, she was

advised to take her sister as a bedfellow, and thus received the itch

again; and the dance of St. Vitus gradually ceased. See Class II. 1. 5. 6.

M. M. Give the patient the itch again. Calomel a grain every night, or

sublimate a quarter of a grain twice a day for a fortnight. Steel. Bark.

Warm-bath. Cold-bath. Opium. Venesection once at the beginning of the

disease. Electricity. Perpetual slow and repeated efforts to move each limb

in the designed direction, as in the titubatio linguae above described.

3. _Risus._ Laughter is a perpetual interruption of voluntary exertion by

the interposition of pleasurable sensation; which not being checked by any

important consequences rises into pain, and requires to be relieved or

moderated by the frequent repetition of voluntary exertion. See Sect.

XXXIV. 1. 4. and Class III. 1. 1. 4. and IV. 1. 3. 3.

4. _Tremor ex ira._ The trembling of the limbs from anger. The interruption

of the voluntary associations of motions by anger, originates from too

great a part of the sensorial power being exerted on the organs of sense;

whence the muscles, which ought to support the body upright, are deprived

of their due quantity, and tremble from debility. See Class III. 2. 1. 1.

5. _Rubor ex ira._ Redness from anger. Anger is an excess of aversion, that

is of voluntarity not yet employed. It is excited by the pain of offended

pride; when it is employed it becomes outrage, cruelty, insanity. The

cutaneous capillaries, especially those of the face, are more mobile, that

is, more easily excited into increased action, or more easily become

torpid, from less variation of sensorial power, than any other parts of the

system, which is owing to their being perpetually subject to the

vicissitudes of heat and cold, and of extension and corrugation. Hence,

when an excess of voluntarity exists without being immediately expended in

the actions of the large muscles, the capillary arteries and glands acquire

more energetic action, and a flushed skin is produced, with increased

secretion of perspirable matter, and consequent heat, owing to the pause or

interruption of voluntary action; and thus the actions of these cutaneous

vessels become associated between the irascent ideas and irascent muscular

actions, which are thus for a time interrupted.

6. _Rubor criminati._ The blushing of accused people, whether guilty or

not, appears to be owing to circumstances similar to that of anger; for in

these situations there is always a sudden voluntarity, or wish, of clearing

their characters arises in the mind of the accused person; which, before an

opportunity is given for it to be expended on the large muscles, influences

the capillary arteries and glands, as in the preceding article. Whence the

increased actions of the capillaries, and the consequent redness and heat,

become exerted between the voluntary ideas of self-defence, and the

muscular actions necessary for that purpose; which last are thus for a time

interrupted or delayed.

Even in the blush of modesty or bashfulness there is a self-condemnation

for some supposed defect or indecorum, and a sudden voluntarity, or wish,

of self-defence; which not being expended in actions of the larger muscles

excites the capillaries into action; which in these subjects are more

mobile than in others.

The blush of young girls on coming into an assembly room, where they expect

their dress, and steps, and manner to be examined, as in dancing a minuet,

may have another origin; and may be considered as a hot fit of returning

confidence, after a previous cold fit of fear.

7. _Tarditas paralytica._ By a stroke of the palsy or apoplexy it

frequently happens, that those ideas, which were associated in trains,

whose first link was a voluntary idea, have their connection dissevered;

and the patient is under the necessity by repeated efforts slowly to renew

their associations. In this situation those words, which have the fewest

other words associated with them, as the proper names of persons or places,

are the most difficult to recollect. And in those efforts of recollection

the word opposite to the word required is often produced, as hot for cold,

winter for summer, which is owing to our associating our ideas of things by

their opposites as well as by their similitudes, and in some instances

perhaps more frequently, or more forcibly. Other paralytic patients are

liable to give wrong names to external objects, as using the word pigs for

sheep, or cows for horses; in this case the association between the idea of

the animal and the name of it is dissevered; but the idea of the class or

genus of the thing remains; and he takes a name from the first of the

species, which presents itself, and sometimes can correct himself, till he

finds the true one.

8. _Tarditas senilis._ Slowness of age. The difficulty of associating ideas

increases with our age; as may be observed from old people forgetting the

business of the last hour, unless they impress it strongly, or by frequent

repetition, though they can well recollect the transactions of their youth.

I saw an elderly man, who could reason with great clearness and precision

and in accurate language on subjects, which he had been accustomed to think

upon; and yet did not know, that he had rang the bell by his fire-side in

one minute afterwards; nor could then recollect the object he had wanted,

when his servant came.

Similar to this is the difficulty which old people experience in learning

new bodily movements, that is, in associating new muscular actions, as in

learning a new trade or manufactury. The trains of movements, which obey

volition, are the last which we acquire; and the first, which are

disassociated.

* * * * *

ORDO II.

_Decreased Associate Motions._

GENUS IV.

_Catenated with External Influences._

As the diseases, which obey solar or lunar periods, commence with torpor or

inactivity, such as the cold paroxysms of fevers, the torpor and consequent

pain of hemicrania, and the pains which precede the fits of epilepsy and

convulsion, it would seem, that these diseases are more generally owing to

the diminution than to the excess of solar or lunar gravitation; as the

diseases, which originate from the influence of the matter of heat, are

much more generally in this country produced by the defect than by the

excess of that fluid.

The periodic returns of so many diseases coincide with the diurnal,

monthly, and annual rounds of time; that any one, who would deny the

influence of the sun and moon on the periods of quotidian, tertian, and

quartan fevers, must deny their effect on the tides, and on the seasons. It

has generally been believed, that solar and lunar effect was exerted on the

blood; which was thus rendered more or less stimulant to the system, as

described in Sect. XXXII. 6. But as the fluid matter of gravitation

permeates and covers all things, like the fluid matter of heat; I am

induced to believe, that gravitation acts in its medium state rather as a

causa sine qua non of animal motion, like heat; which may disorder the

system chemically or mechanically, when it is diminished; but may

nevertheless stimulate it, when increased, into animal exertion.

Without heat and motion, which some philosophers still believe to be the

same thing, as they so perpetually appear together, the particles of matter

would attract and move towards each other, and the whole universe freeze or

coalesce into one solid mass. These therefore counteract the gravitation of

bodies to one center; and not only prevent the planets from falling into

the sun, but become either the efficient causes of vegetable and animal

life, or the causes without which life cannot exist; as by their means the

component particles of matter are enabled to slide over each other with all

the various degrees of fluidity and repulsion.

As the attraction of the moon countervails or diminishes the terrene

gravitation of bodies on the surface of the earth; a tide rises on that

side of the earth, which is turned towards the moon; and follows it, as the

earth revolves. Another tide is raised at the same time on the opposite

side of the revolving earth; which is owing to the greater centrifugal

motion of that side of the earth, which counteracts the gravitation of

bodies near its surface. For the earth and moon may be considered as two

cannon balls of different sizes held together by a chain, and revolving

once a month round a common center of gravity between them, near the

earth's surface; at the same time that they perform their annual orbits

round the sun. Whence the centrifugal force of that side of the earth,

which is farthest from this center of motion, round which the earth and

moon monthly revolve, is considerably greater, than the centrifugal force

of that side of the earth, which is nearest it; to which should be added,

that this centrifugal force not only contributes to diminish the terrene

gravitation of bodies on the earth's surface on that side furthest from

this center of motion, but also to increase it on that side, which is

nearest it.

Another circumstance, which tends to raise the tide on the part of the

earth's surface, which is most distant from the moon, is, that the

attraction of the moon is less on that part of the ocean, than it is on the

other parts of the earth. Thus the moon may be supposed to attract the

water on the side of the earth nearest it with a power equal to three; and

to attract the central parts of the earth with a power equal to two; and

the water on the part of the earth most distant from the moon with a power

only equal to one. Hence on the side of the earth most distant from the

moon, the moon's attraction is less, and the centrifugal force round their

common center of motion is greater; both which contribute to raise the

tides on that side of the earth. On the side of the earth nearest the moon,

the moon's attraction is so much greater as to raise the tides; though the

centrifugal force of the surface of the earth round their common center of

motion in some degree opposes this effect.

On these accounts, when the moon is in the zenith or nadir, the gravitation

of bodies on the earth's surface will be greatest at the two opposite

quadratures; that is, the greatest gravitation of bodies on the earth's

surface towards her center during the lunar day is about six hours and an

half after the southing, or after the northing of the moon.

Circumstances similar to these, but in a less degree, must occur in respect

to the solar influence on terrestrial bodies; that is, there must be a

diminution of the gravity of bodies, near the earth's surface at noon, when

the sun is over them; and also at midnight from the greater centrifugal

force of that side of the earth, which is most distant from the center,

round which the earth moves in her annual orbit, than on the side nearest

that center. Whence it likewise follows, that the gravitation of bodies

towards the earth is greatest about six hours after noon, and after

midnight.

Now when the sun and moon have their united gravitation on the same side of

the earth, as at the new moon; or when the solar attraction coincides with

the greater centrifugal motion of that side of the earth, which is furthest

distant from the moon, as at the full moon; and when this happens about

noon or midnight, the gravitation of terrene bodies towards the earth will

be greater about six hours after noon, and after midnight, than at any

other part of the lunar period; because the attraction of both these

luminaries is then exerted on those sides of the earth over which they

hang, which at other times of the month are more or less exerted on other

parts of it.

Lastly, as heat and motion counteract the gravitation of the particles of

bodies to each other, and hence become either the efficient causes of

vegetable and animal life, or the causes without which life cannot exist,

it seems to follow, that when our gravitation towards the earth's center is

greatest, the powers of life should be the least; and hence that those

diseases, which begin with torpor, should occur about six hours after the

solar or lunar noon, or about six hours after the solar or lunar midnight;

and this most frequently about six hours after or before the new or full

moon; and especially when these happen at noon or at midnight; or lastly,

according to the combination of these powers in diminishing or increasing

the earth's attraction to bodies on its surface.

The returns or exacerbations of many fevers, both irritative and

inflammatory, about six in the evening, and of the periodic cough described

in Sect. XXXVI. 3. 9. countenance this theory. Tables might be made out to

shew the combined powers of the sun and moon in diminishing the gravitation

of bodies on the earth's surface, at every part of their diurnal, monthly,

and annual periods; and which might facilitate the elucidation of this

subject. But I am well aware of the difficulty of its application to

diseases, and hope these conjectures may induce others to publish more

numerous observations, and more conclusive reasonings.

SPECIES.

1. _Somni periodus._ The periods of sleeping and of waking are shortened or

prolonged by so many other circumstances in animal life, besides the minute

difference between diurnal and nocturnal solar gravitation, that it can

scarcely be ascribed to this influence. At the same time it is curious to

observe, that vegetables in respect to their times of sleeping more

regularly observe the hour of the day, than the presence or absence of

light, or of heat, as may be seen by consulting the calendar of Flora.

Botanic Garden, Part II. Canto 2. l. 165. note.

Some diseases, which at first sight might be supposed to be influenced by

solar periods, seem to be induced by the increasing sensibility of the

system to pain during our sleeping hours; as explained in Sect. XVIII. 15.

Of these are the fits of asthma, of some epilepsies, and of some

haemoptoes; all which disturb the patient after some hours sleep, and are

therefore to be ascribed to the increase of our dormant sensibility. There

may likewise be some doubt, whether the commencement of the pain of gout in

the foot, as it generally makes its attack after sleep, should be ascribed

to the increased sensibility in sleep, or to solar influence?

M. M. When asthmatic or epileptic fits or haemoptoe occur after a certain

number of hours of sleep, the patient should be forcibly awakened before

the expected time by an alarm clock, and drink a cup of chocolate or

lemonade.--Or a grain of opium should be given at going to bed.--In one

case to prevent the too great increase of sensibility by shortening the

time of sleep; and in the other by increasing the irritative motions, and

expending by that means a part of the sensorial power.

2. _Studii inanis periodus._ Class III. 1. 2. 2. The cataleptic spasm which

preceded the reverie and somnambulation in the patient, whose case is

related in Sect. XIX. 2. occurred at exactly the same hour, which was about

eleven in the morning for many weeks; till those periods were disturbed by

large doses of opium; and must therefore be referred to some effect of

solar gravitation. In the case of Master A. Sect. XXXIV. 3. as the reverie

began early in the morning during sleep, there may be a doubt, whether this

commenced with torpor of some organ catenated with solar gravitation; or

was caused by the existence of a previous torpid part, which only became so

painful as to excite the exertions of reverie by the perpetual increase of

sensibility during the continuance of sleep, as in some fits of epilepsy,

asthma, and haemoptoe mentioned in the preceding article.

3. _Hemicraniae periodus._ Periods of hemicrania. Class IV. 2. 2. 8. The

torpor and consequent pain of some membranes on one side of the head, as

over one eye, is frequently occasioned by a decaying tooth, and is liable

to return every day, or on alternate days at solar or lunar periods. In

this case large quantities of the bark will frequently cure the disease,

and especially if preceded by venesection and a brisk cathartic; but if the

offending tooth can be detected, the most certain cure is its extraction.

These partial head-achs are also liable to return at the greater lunar

periods, as about once a month. Five drops from a two-ounce phial of a

saturated solution of arsenic twice a day for a week or two have been said

to prevent the returns of this disease. See a Treatise on Arsenic by Dr.

Fowler, of York. Strong errhines have also been recommended.

4. _Epilepsiae dolorificae periodus._ Class III. 1. 1. 8. The pain which

induces after about an hour the violent convulsions or insanity, which

constitute the painful epilepsy, generally observe solar diurnal periods

for four or five weeks, and are probably governed by solar and lunar times

in respect to their greater periods; for I have observed that the daily

paroxysms, unless disturbed by large doses of opium, recur at very nearly

the same hour, and after a few weeks the patients have recovered to relapse

again at the interval of a few months. But more observations are wanted

upon this subject, which might be of great advantage in preventing the

attacks of this disease; as much less opium given an hour before its

expected daily return will prevent the paroxysm, than is necessary to cure

it, after it has commenced.

5. _Convulsionis dolorificae periodus._ Class III. 1. 1. 6. The pains,

which produce these convulsions, are generally left after rheumatism, and

come on when the patients are become warm in bed, or have been for a short

time asleep, and are therefore perhaps rather to be ascribed to the

increasing sensibility of the system during sleep, than to solar diurnal

periods, as in Species first and second of this Genus.

6. _Tussis periodicae periodus._ Periodic cough, Class IV. 2. 1. 9. returns

at exact solar periods; that described in Sect. XXXVI. 3. 9. recurred about

seven in the afternoon for several weeks, till its periods were disturbed

by opium, and then it recurred at eleven at night for about a week, and was

then totally destroyed by opium given in very large quantities, after

having been previously for a few days omitted.

7. _Catameniae periodus._ Periods of menstruation. The correspondence of

the periods of the catamenia with those of the moon was treated of in Sect.

XXXII. 6. and can admit of no more doubt, than that the returns of the

tides are governed by lunar influence. But the manner in which this is

produced, is less evident; it has commonly been ascribed to some effect of

the lunar gravitation on the circulating blood, as mentioned in Sect.

XXXII. 6. But it is more analogous to other animal phenomena to suppose

that the lunar gravitation immediately affects the solids by its influx or

stimulus. Which we believe of the fluid element of heat, in which we are

equally immersed; and of the electric fluid, which also surrounds and

pervades us. See Sect. XXXVI. 2. 3.

If the torpor of the uterine veins, which induces the monthly periods of

the catamenia, be governed by the increase of terrene gravitation; that is,

by the deficiency of the counter-influence of solar and lunar gravitation;

why does not it occur most frequently when the terrene gravitation is the

greatest, as about six hours after the new moon, and next to that at about

six hours after the full moon? This question has its difficulty; first, if

the terrene gravitation be greatest about six hours after the new moon, it

must become less and less about the same time every lunar day, till the end

of the first quarter, when it will be the least; it must then increase

daily till the full. After the full the terrene gravitation must again

decrease till the end of the third quarter, when it will again be the

least, and must increase again till the new moon; that is, the solar and

lunar counter-gravitation is greatest, when those luminaries are vertical,

at the new moon, and full moon, and least about six hours afterwards. If it

was known, whether more menstruations occur about six hours after the moon

is in the zenith or nadir; and in the second and fourth quarters of the

moon, than in the first and third; some light would be thrown on this

subject; which must in that respect wait for future observations.

Secondly, if the lunar influence produces a very small degree of

quiescence, suppose of the uterine veins, at first; and if that recurs at

certain periods, as of lunar days, or about 25 hours, even with less power

to produce quiescence than at first; yet the quiescence will daily increase

by the acquired habit acting at the same time, as explained in Sect. XII.

3. 3. till at length so great a degree of quiescence will be induced as to

cause the inaction of the veins of the uterus, and consequent venous

haemorrhage. See Sect. XXXII. 6. Class I. 2. 1. 11. IV. 1. 4. 4. See the

introduction to this Genus.

8. _Haemorrhoidis periodus._ The periods of the piles depend on the torpor

of the veins of the rectum, and are believed to recur nearly at monthly

intervals. See Sect. XXVII. 2. and Class I. 2. 1. 6.

9. _Podagrae periodus._ The periods of gout in some patients recur at

annual intervals, as in the case related above in Class IV. 1. 2. 15. in

which the gouty paroxysm returned for three successive years on nearly the

same day of the month. The commencement of the pain of each paroxysm is

generally a few hours after midnight, and may thence either be induced by

diurnal solar periods, or by the increasing sensibility during sleep, as

mentioned in the first species of this genus.

10. _Erysipelatis periodus._ Some kinds of erysipelas which probably

originate from the association of the cutaneous vessels with a diseased

liver, occur at monthly periods, like the haemorrhois or piles; and others

at annual periods like the gout; as a torpor of some part I suppose always

precedes the erysipelatous inflammation, the periods should accord with the

increasing influence of terrene gravitation, as described in the

introduction to this Genus, and in Species the seventh of it. Other periods

of diseases referable to solar and lunar influence are mentioned in Sect

XXXVI. and many others will probably be discovered by future observation.

11. _Febrium periodus._ Periods of fevers. The commencement of the cold

fits of intermittent fevers, and the daily exacerbations of other fevers,

so regularly recur at diurnal solar or lunar periods, that it is impossible

to deny their connection with gravitation; as explained in Sect. XXXVI. 3.

Not only these exacerbations of fever, and their remissions, obey the

diurnal solar and lunar periods; but the preparatory circumstances, which

introduce fevers, or which determine their crisises, appear to be governed

by the parts of monthly lunar periods, and of solar annual ones. Thus the

variolous fever in the natural small-pox commences on the 14th day, and in

the inoculated small-pox on the seventh day. The fever and eruption in the

distinct kind take up another quarter of a lunation, and the maturation

another quarter.

The fever, which is termed canine madness, or hydrophobia, is believed to

commence near the new or full moon; and, if the cause is not then great

enough to bring on the disease, it seems to acquire some strength, or to

lie dormant, till another, or perhaps more powerful lunation calls it into

action. In the spring, about three or four years ago, a mad dog very much

worried one swine confined in a sty, and bit another in the same sty in a

less degree; the former became mad, refused his meat, was much convulsed,

and died in about four days; this disease commenced about a month after the

bite. The other swine began to be ill about a month after the first, and

died in the same manner.

* * * * *

ORDO III.

_Retrograde Associate Motions._

GENUS I.

_Catenated with Irritative Motions._

Those retrograde associate motions, the first links of which are catenated

with irritative motions, belong to this genus. All the retrograde motions

are consequent to debility, or inactivity, of the organ; and therefore

properly belong to the genera of decreased actions both in this and the

former classes.

SPECIES.

1. _Diabaetes irritata._ When the absorbents of the intestines are

stimulated too strongly by spirit of wine, as in the beginning of

drunkenness, the urinary absorbents invert their motions. The same happens

from worms in the intestines. In other kinds of diabetes may not the remote

cause be the too strong action of the cutaneous absorbents, or of the

pulmonary ones? May not in such cases oil externally or internally be of

service? or warm bathing for an hour at a time? In hysteric inversions of

motion is some other part too much stimulated? or pained from the want of

stimulus?

2. _Sudor frigidus in asthmate._ The cause of the paroxysms of humoral

asthma is not well understood; I suppose it to be owing to a torpidity or

inaction of the absorbents belonging to the pulmonary vessels, as happens

probably to other viscera at the commencement of intermittent fevers, and

to a consequent accumulation of fluids in them; which at length producing

great irritation or uneasy sensation causes the violent efforts to produce

the absorption of it. The motions of the cutaneous absorbent vessels by

their association with those of the pulmonary ones become retrograde, and

effuse upon the skin a fluid, which is said to be viscid, and which adheres

in drops.

A few days ago I saw a young man of delicate constitution in what was

called a fit of the asthma; he had about two months before had a

peripneumony, and had been ever since subject to difficult respiration on

exertion, with occasional palpitation of his heart. He was now seized about

eight at night after some exertion of mind in his business with cold

extremities, and difficulty of breathing. He gradually became worse, and in

about half an hour, the palpitation of his heart and difficult respiration

were very alarming; his whole skin was cold and pale, yet he did not

shudder as in cold paroxysm of fever; his tongue from the point to the

middle became as cold as his other extremities, with cold breath. He seemed

to be in the act of dying, except that his pulse continued equal in time,

though very quick. He lost three ounces of blood, and took ten drops of

laudanum with musk and salt of hartshorn, and recovered in an hour or two

without any cold sweat.

There being no cold sweat seems to indicate, that there was no accumulation

of serous fluid in the lungs; and that their inactivity, and the coldness

of the breath, was owing to the sympathy of the air-cells with some distant

part. There was no shuddering produced, because the lungs are not sensible

to heat and cold; as any one may observe by going from a warm room into a

frosty air, and the contrary. So the steam of hot tea, which scalds the

mouth, does not affect the lungs with the sensation of heat. I was induced

to believe, that the whole cold fit might be owing to suppuration in some

part of the chest; as the general difficulty of breathing seemed to be

increased after a few days with pulse of 120, and other signs of empyema.

Does the cold sweat, and the occurrence of the fits of asthma after sleep,

distinguish the humoral asthma from the cold paroxysm of intermittents, or

which attends suppuration, or which precedes inflammation?--I heard a few

weeks afterwards, that he spit up much matter at the time he died.

3. _Diabaetes a timore._ The motions of the absorbent vessels of the neck

of the bladder become inverted by their consent with those of the skin;

which are become torpid by their reverse sympathy with the painful ideas of

fear, as in Sect. XVI. 8. 1. whence there is a great discharge of pale

urine, as in hysteric diseases.

The same happens from anxiety, where the painful suspense is continued,

even when the degree of fear is small; as in young men about to be examined

for a degree at the universities the frequency of making water is very

observable. When this anxiety is attended with a sleepless night, the

quantity of pale urine is amazingly great in some people, and the

micturition very frequent.

M. M. Opium. Joy. Consolations of friendship.

4. _Diarrhoea a timore._ The absorbent vessels of the intestines invert

their motions by direct consent with the skin; hence many liquid stools as

well as much pale urine are liable to accompany continued fear, along with

coldness of the skin. The immediate cause of this is the decreased

sensorial power of association, which intervenes between the actions of the

absorbents of the cold skin, and those of the intestinal absorbents; the

motions of the latter become on that account weakened and at length

retrograde. The remote cause is the torpor of the vessels of the skin

catenated with the pain of fear, as explained in Sect. XVI. 8. 1.

The capillaries of the skin consent more generally by direct sympathy with

those of the lower intestines, and of the bladder; but by reverse sympathy

more generally with those of the stomach and upper intestines. As appears

in fevers, where the hot skin accompanies indigestion of the stomach; and

in diarrhoeas attended with cold extremities.

The remote cause is the torpor of the skin owing to its reverse sympathy

with the painful sensual motions, or ideas, of fear; which are now actuated

with great energy, so as to deprive the second link of associated motions

of their due share of sensorial power. It is also probable, that the pain

of fear itself may contribute to exhaust the sensorial power, even when it

produces no muscular action. See Class IV. 2. 2.

5. _Pallor et tremor a timore._ A retrograde action of the capillaries of

the skin producing paleness, and a torpor of the muscular fibres of the

limbs occasioning trembling, are caused by their reverse associations with

the ideas or imaginations of fear; which are now actuated with violent

energy, and accompanied with great pain. The cause of these associations

are explained in Sect XVI. 8. 1.

These torpid actions of the capillaries and muscles of the limbs are not

caused immediately by the painful sensation of fear; as in that case they

would have been increased and not decreased actions, as occurs in anger;

where the painful volition increases the actions of the capillaries,

exciting a blush and heat of the skin. Whence we may gain some knowledge of

what is meant by depressing and exciting passions; the former confiding of

ideas attended with pain, which pain occasions no muscular actions, like

the pain of cold head-ach; the latter being attended with volitions, and

consequent muscular exertions.

That is, the pain of fear, and the pain of anger, are produced by the

exertion of certain ideas, or motions of certain nerves of sense; in the

former case, the painful sensation of fear produces no muscular actions,

yet it exhausts or employs so much sensorial power, that the whole system

acts more feebly, or becomes retrograde; but some parts of it more so than

others, according to their early associations described in Sect. XVI. 8. 1.

hence the tremor of the limbs, palpitation of heart, and even syncope. In

anger the painful volition produces violent muscular actions; but if

previous to these any deliberation occurs, a flushed countenance sometimes,

and a red skin, are produced by this superabundance of volition exerted on

the arterial system; but at other times the skin becomes pale, and the legs

tremble, from the exhaustion or expenditure of the sensorial power by the

painful volitions of anger on the organs of sense, as by the painful

sensations of fear above mentioned.

Where the passion of fear exists in a great degree, it exhausts or expends

so much sensorial power, either simply by the pain which attends it, or by

the violent and perpetual excitement of the terrific imaginations or ideas,

that not only a cold and pale skin, but a retrograde motion of the

cutaneous absorbents occurs, and a cold sweat appears upon the whole

surface of the body, which probably sometimes increases pulmonary

absorption; as in Class II. 1. 6. 4. and as in the cold sweats, which

attend the paroxysms of humoral asthma. Hence anxiety, which is a continued

pain of fear, so universally debilitates the constitution as to occasion a

lingering death; which happens much more frequently than is usually

supposed; and these victims of continued anxiety are said to die of a

broken heart. Other kinds of paleness are described in Class I. 2. 2. 2.

M. M. Opium. Wine. Food. Joy.

6. _Palpitatio cordis a timore._ The palpitation of the heart from fear is

owing to the weak action of it, and perhaps sometimes to the retrograde

exertion of the ventricules and auricles; because it seems to be affected

by its association with the capillaries, the actions of which, with those

of the arteries and veins, constitute one great circle of associate

motions. Now when the capillaries of the skin become torpid, coldness and

paleness succeed; and with these are associated the capillaries of the

lungs, whence difficult respiration; and with these the weak and retrograde

actions of the heart. At the same time the absorbents of the skin, and of

the bladder, and of the intestines, sometimes become retrograde, and

regurgitate their contents; as appears by the pale urine in large

quantities, which attends hysteric complaints along with this palpitation

of the heart; and from the cold sweats, and diarrhoea; all which, as well

as the hysteric complaints, are liable to be induced or attended by fear.

When fear has still more violently affected the system, there have been

instances where syncope, and sudden death, or a total stoppage of the

circulation, have succeeded: in these last cases, the pain of fear has

employed or exhausted the whole of the sensorial power, so that not only

those muscular fibres generally exerted by volition cease to act, whence

the patient falls down; and those, which constitute the organs of sense,

whence syncope; but lastly those, which perform the vital motions, become

deprived of sensorial power, and death ensues. See Class. I. 2. 1. 4. and

I. 2. 1. 10. Similar to this in some epileptic fits the patient first

suddenly falls down, without even endeavouring to save himself by his hands

before the convulsive motions come on. In this case the great exertion of

some small part in consequence of great irritation or sensation exhausts

the whole sensorial power, which was lodged in the extremities of the

locomotive nerves, for a short time, as in syncope; and as soon as these

muscles are again supplied, convulsions supervene to relieve the painful

sensation. See Class III. 1. 1. 7.

7. _Abortio a timore._ Women miscarry much more frequently from a fright,

than from bodily injury. A torpor or retrograde motion of the capillary

arteries of the internal uterus is probably the immediate cause of these

miscarriages, owing to the association of the actions of those vessels with

the capillaries of the skin, which are rendered torpid or retrograde by

fear. By this contraction of the uterine arteries, the fine vessels of the

placenta, which are inserted into them, are detruded, or otherwise so

affected, that the placenta separates at this time from the uterus, and the

fetus dies from want of oxygenation. A strong young woman, in the fifth or

sixth month of her pregnancy, who has since borne many children, went into

her cellar to draw beer; one of the servant boys was hid behind a barrel,

and started out to surprise her, believing her to be the maid-servant; she

began to flood immediately, and miscarried in a few hours. See Sect. XXXIX.

6. 5. and Class I. 2. 1. 14.

8. _Hysteria a timore._ Some delicate ladies are liable to fall into

hysteric fits from sudden fright. The peristaltic motions of the bowels and

stomach, and those of the oesophagus, make a part of the great circle of

irritative motions with those of the skin, and many other membranes. Hence

when the cutaneous vessels become torpid from their reverse sympathy with

the painful ideas of fear; these of the bowels, and stomach, and

oesophagus, become first torpid by direct sympathy with those of the skin,

and then feebly and ineffectually invert the order of their motions, which

constitutes a paroxysm of the hysteric disease. See Class I. 3. 1. 10.

These hysteric paroxysms are sometimes followed by convulsions, which

belong to Class III. as they are exertions to relieve pain; and sometimes

by death. See Species 9 of this Genus, and Class I. 2. 1. 4.

Indigestion from fear is to be ascribed in the same manner to the torpor of

the stomach, owing to its association with the skin. As in Class IV. 1. 2.

5. IV. 2. 1.

* * * * *

ORDO III.

_Retrograde Associate Motions._

GENUS II.

_Catenated with Sensitive Motions._

SPECIES.

1. _Nausea idealis._ Nausea from disgustful ideas, as from nauseous

stories, or disgustful sights, or smells, or tastes, as well as vomiting

from the same causes, consists in the retrograde actions of the lymphatics

of the throat, and of the oesophagus, and stomach; which are associated

with the disgustful ideas, or sensual motions of sight, or hearing, or

smell, or taste; for as these are decreased motions of the lymphatics, or

of the oesophagus, or stomach, they cannot immediately be excited by the

sensorial power of painful sensation, as in that case they ought to be

increased motions. So much sensorial power is employed for a time on the

disgustful idea, or expended in the production of inactive pain, which

attends it, that the other parts of the associated chain of action, of

which this disgustful idea is now become a link, is deprived of their

accustomed share; and therefore first stop, and then invert their motions.

Owing to deficiency of sensorial power, as explained more at large in Sect.

XXXV. 1. 3.

2. _Nausea a conceptu._ The nausea, which pregnant women are so subject to

during the first part of gestation, is owing to the reverse sympathy

between the uterus and stomach, so that the increased action of the former,

excited by the stimulus of the growing embryon, which I believe is

sometimes attended with sensation, produces decreased actions of the latter

with the disagreeable sensation of sickness with indigestion and consequent

acidity. When the fetus acquires so much muscular power as to move its

limbs, or to turn itself, which is called quickening, this sickness of

pregnancy generally ceases.

M. M. Calcined magnesia. Rhubarb. Half a grain of opium twice a day.

Recumbent posture on a sofa.

3. _Vomitio vertiginosa._ Sea-sickness, the irritative motions of vision,

by which we balance ourselves, and preserve our perpendicularity, are

disturbed by the indistinctness of their objects; which is either owing to

the similarity of them, or to their distance, or to their apparent or

unusual motions. Hence these irritative motions of vision are exerted with

greater energy, and are in consequence attended with sensation; which, at

first is agreeable, as when children swing on a rope; afterwards the

irritative motions of the stomach, and of the absorbent vessels, which open

their mouths into it, become inverted by their associations with them by

reverse sympathy.

For the action of vomiting, as well as the disagreeable sensation of

sickness, are shewn to be occasioned by defect of the sensorial power;

which in this case is owing to the greater expenditure of it by the sense

of vision. On the same account the vomiting, which attends the passage of a

stone through the ureter, or from an inflammation of the bowels, or in the

commencement of some fevers, is caused by the increased expenditure of the

sensorial power by the too great action of some links of the associations

of irritative motions; and there being in consequence a deficiency of the

quantity required for other links of this great catenation.

It must be observed, that the expenditure of sensorial power by the retinas

of the eyes is very great; which may be estimated by the perpetual use of

those organs during our waking hours, and during most of our sleeping ones;

and by the large diameters of the two optic nerves, which are nearly the

size of a quill, or equal to some of the principal nerves, which serve the

limbs.

4. _Vomitio a calculo in uretere._ The action of vomiting in consequence of

the increased or decreased actions of the ureter, when a stone lodges in

it. The natural actions of the stomach, which consist of motions subject to

intermitted irritations from the fluids, which pass through it, are

associated with those of the ureter; and become torpid, and consequently

retrograde, by intervals, when the actions of the ureter becomes torpid

owing to previous great stimulus from the stone it contains; as appears

from the vomiting existing when the pain is least. When the motions of the

ureter are thus lessened, the sensorial power of association, which ought

to actuate the stomach along with the sensorial power of irritation, ceases

to be excited into action; and in consequence the actions of the stomach

become less energetic, and in consequence retrograde.

For as vomiting is a decreased action of the stomach, as explained in Sect.

XXXV. 1. 3. it cannot be supposed to be produced by the pain of gravel in

the ureter alone, as it should then be an increased action, not a decreased

one.

The perpetual vomiting in ileus is caused in like manner by the defective

excitement of the sensorial power of association by the bowel, which is

torpid during the intervals of pain; and the stomach sympathizes with it.

See Enteritis, Class II. 1. 2. 11. Does this symptom of vomiting indicate,

whether the disease be above or below the valve of the colon? Does not the

softer pulse in some kinds of enteritis depend on the sympathy of the heart

and arteries with the sickness of the stomach? See Ileus and Cholera.

Hence this sickness, as well as the sickness in some fevers, cannot be

esteemed an effort of nature to dislodge any offensive material; but like

the sea-sickness described above, and in Sect. XX. 4. is the consequence of

the associations of irritative or sensitive motions. See Class I. 1. 3. 9.

5. _Vomitio ab insultu paralytico._ Paralytic affections generally commence

with vomiting, the same frequently happens from a violent blow with a stick

on the head; this curious connection of the brain and stomach has not been

explained; as it resembles the sickness in consequence of vertigo at sea,

it would seem to arise from a similar cause, viz. from disturbed irritative

or sensitive associations.

6. _Vomitio a titillatione faucium._ If the throat be slightly tickled with

a feather, a nausea is produced, that is, an inverted action of the mouths

of the lymphatics of the fauces, and by direct sympathy an inverted action

of the stomach ensues. As these parts have frequently been stimulated at

the same time into pleasurable action by the deglutition of our daily

aliment, their actions become strongly associated. And as all the food, we

swallow, is either moist originally, or mixed with our moist saliva in the

mouth; a feather, which is originally dry, and which in some measure repels

the moist saliva, is disagreeable to the touch of the fauces; at the same

time this nausea and vomiting cannot be caused by the disagreeable

sensation simply, as then they ought to have been increased exertions, and

not decreased ones, as shewn in Section XXXV. 1. 3. But the mouths of the

lymphatics of the fauces are stimulated by the dry feather into too great

action for a time, and become retrograde afterwards by the debility

consequent to too great previous stimulus.

7. _Vomitio cute sympathetica._ Vomiting is successfully stopped by the

application of a blister on the back in some fevers, where the extremities

are cold, and the skin pale. It was stopped by Sydenham by producing a

sweat on the skin by covering the head with the bed-clothes. See Class IV.

1. 1. 3. and Suppl. I. 11. 6.

* * * * *

ORDO III.

_Retrograde Associate Motions._

GENUS III.

_Catenated with Voluntary Motions._

SPECIES.

1. _Ruminatio._ In the rumination of horned cattle the food is brought up

from the first stomach by the retrograde motions of the stomach and

oesophagus, which are catenated with the voluntary motions of the abdominal

muscles.

2. _Vomitio voluntaria._ Voluntary vomiting. Some human subjects have been

said to have obtained this power of voluntary action over the retrograde

motions of the stomach and oesophagus, and thus to have been able to empty

their stomach at pleasure. See Sect. XXV. 6. This voluntary act of emptying

the stomach is possessed by some birds, as the pigeon; who has an organ for

secreting milk in its stomach, as Mr. Hunter observed; and softens the food

for its young by previously swallowing it; and afterwards putting its bill

into theirs returns it into their mouths. See Sect. XXXIX. 4. 8. The

pelicans use a stomach, or throat bag, for the purpose of bringing the

fish, which they catch in the sea to shore, and then eject them, and eat

them at their leisure. See Sect. XVI. 11. And I am well informed of a

bitch, who having puppies in a stable at a distance from the house,

swallowed the flesh-meat, which was given her, in large pieces, and

carrying it immediately to her whelps, brought it up out of her stomach,

and laid it down before them.

3. _Eructatio voluntaria._ Voluntary eructation. Some, who have weak

digestions, and thence have frequently been induced to eruct the quantity

of air discharged from the fermenting aliment in their stomachs, have

gradually obtained a power of voluntary eructation, and have been able thus

to bring up hogsheads of air from their stomachs, whenever they pleased.

This great quantity of air is to be ascribed to the increase of the

fermentation of the aliment by drawing off the gas as soon as it is

produced. See Sect. XXIII. 4.

* * * * *

ORDO III.

_Retrograde Associate Motions._

GENUS. IV.

_Catenated with External Influences._

SPECIES.

1. _Catarrhus periodicus._ Periodical catarrh is not a very uncommon

disease; there is a great discharge of a thin saline mucous material from

the membranes of the nostrils, and probably from the maxillary and frontal

sinuses, which recur once a day at exact solar periods; unless it be

disturbed by the exhibition of opium; and resembles the periodic cough

mentioned below. See Class I. 3. 2. 1. It is probably owing to the

retrograde action of the lymphatics of the membranes affected, and produced

immediately by solar influence.

2. _Tussis periodica._ Periodic cough, called nervous cough, and tussis

serina. It seems to arise from a periodic retrograde action of the

lymphatics of the membrane, which lines the air-cells of the lungs. And the

action of coughing, which is violently for an hour or longer, is probably

excited by the stimulus of the thin fluid thus produced, as well as by the

disagreeable sensation attending membranous inactivity; and resembles

periodic catarrh not only in its situation on a mucous membrane, but in the

discharge of a thin fluid. As it is partly restrainable, it does not come

under the name of convulsion; and as it is not attended with difficult

respiration, it cannot be called asthma; it is cured by very large doses of

opium, see a case and cure in Sect. XXXVI. 3. 9. see Class IV. 2. 4. 6. and

seems immediately to be induced by solar influence.

3. _Histeria a frigore._ Hysteric paroxysms are occasioned by whatever

suddenly debilitates the system, as fear, or cold, and perhaps sometimes by

external moisture of the air, as all delicate people have their days of

greater or less debility, see Class IV. 3. 1. 8.

4. _Nausea pluvialis._ Sickness at the commencement of a rainy season is

very common among dogs, who assist themselves by eating the agrostris

canina, or dog's grass, and thus empty their stomachs. The same occurs with

less frequency to cats, who make use of the same expedient. See Sect. XVI.

11. I have known one person, who from his early years has always been sick

at the beginning of wet weather, and still continues so. Is this owing to a

sympathy of the mucous membrane of the stomach with the mechanical

relaxation of the external cuticle by a moister atmosphere, as is seen in

the corrugated cuticle of the hands of washing-women? or does it sympathize

with the mucous membrane of the lungs, which must be affected along with

the mucus on its surface by the respiration of a moister atmosphere?

* * * * *

SUPPLEMENT TO CLASS IV.

_Sympathetic Theory of Fever._

As fever consists in the increase or diminution of direct or reverse

associated motions, whatever may have been the remote cause of them, it

properly belongs to the fourth class of diseases; and is introduced at the

end of the class, that its great difficulties might receive elucidation

from the preceding parts of it. These I shall endeavour to enumerate under

the following heads, trusting that the candid reader will discover in these

rudiments of the theory of fever a nascent embryon, an infant Hercules,

which Time may rear to maturity, and render serviceable to mankind.

I. Simple fever of two kinds.

II. Compound fever.

III. Termination of the cold fit.

IV. Return of the cold fit.

V. Sensation excited in fever.

VI. Circles of associated motions.

VII. Alternations of cold and hot fits.

VIII. Orgasm of the capillaries.

IX. Torpor of the lungs.

X. Torpor of the brain.

XI. Torpor of the heart and arteries.

XII. Torpor of the stomach and intestines.

XIII. Case of continued fever explained.

XIV. Termination of continued fever.

XV. Inflammation excited in fever.

XVI. Recapitulation.

I. _Simple fever._

1. When a small part of the cutaneous capillaries with their mucous or

perspirative glands are for a short time exposed to a colder medium, as

when the hands are immersed in iced water for a minute, these capillary

vessels and their glands become torpid or quiescent, owing to the eduction

of the stimulus of heat. The skin then becomes pale, because no blood

passes through the external capillaries; and appears shrunk, because their

sides are collapsed from inactivity, not contracted by spasm; the roots of

the hair are left prominent from the seceding or subsiding of the skin

around them; and the pain of coldness is produced.

In this situation, if the usual degree of warmth be applied, these vessels

regain their activity; and having now become more irritable from an

accumulation of the sensorial power of irritation during their quiescence,

a greater exertion of them follows, with an increased glow of the skin, and

another kind of pain, which is called the hot-ach; but no fever, properly

so called, is yet produced; as this effect is not universal, nor permanent,

nor recurrent.

2. If a greater part of the cutaneous capillaries with their mucous and

perspirative glands be exposed for a longer time to cold, the torpor or

quiescence becomes extended by direct sympathy to the heart and arteries;

which is known by the weakness, and consequent frequency of the pulse in

cold fits of fever.

This requires to be further explained. The movements of the heart and

arteries, and the whole of the circulatory vessels, are in general excited

into action by the two sensorial powers of irritation, and of association.

The former is excited by stimulus, the latter by the previous actions of a

part of the vital circle of motions. In the above situation the capillaries

act weakly from defect of irritation, which is caused by deficient stimulus

of heat; but the heart and arteries act weakly from defect of association,

which is owing to the weak action of the capillaries; which does not now

excite the sensorial power of association into action with sufficient

energy.

After a time, either by the application of warmth, or by the increase of

their irritability owing to the accumulation of the sensorial power of

irritation during their previous quiescence, the capillary vessels and

glands act with greater energy than natural; whence the red colour and heat

of the skin. The heart and arteries acquire a greater strength of

pulsation, and continue the frequency of it, owing to the accumulation of

the sensorial power of association during their previous torpor, and their

consequent greater associability; which is now also more strongly excited

by the increased actions of the capillaries. And thus a fit of simple fever

is produced, which is termed Febris irritativa; and consists of a torpor of

the cutaneous capillaries with their mucous and perspirative glands,

accompanied with a torpor of the heart and arteries; and afterwards of an

increased action of all these vessels, by what is termed direct sympathy.

This fever, with strong pulse without inflammation, or febris irritativa,

described in Class I. 1. 1. 1. is frequently seen in vernal intermittents,

as the orgasm of the heart and arteries is then occasioned by their

previous state of torpor; but more rarely I believe exists in the type of

continued fever, except there be an evident remission, or approximation to

a cold fit; at which time a new accumulation of the sensorial power of

association is produced; which afterwards actuates the heart and arteries

with unnatural vigour; or unless there be some stimulus perpetually acting

on the system so as to induce an increased secretion of sensorial power in

the brain, as occurs in slight degrees of intoxication. Since without one

or other of these circumstances in continued fevers without inflammation,

that is, without the additional sensorial power of sensation being

introduced, it seems difficult to account for the production of so great a

quantity of sensorial power, as must be necessary to give perpetual

increase of action to the whole sanguiferous system.

3. On the contrary, while the cutaneous capillaries with their mucous and

perspirative glands acquire an increased irritability, as above, by the

accumulation of that sensorial power during their previous quiescence, and

thus constitute the hot fit of fever; if the heart and arteries do not

acquire any increase of associability, but continue in their state of

torpor, another kind of simple fever is produced; which is generally of the

continued kind, and is termed Febris inirritativa; which consists of a

previous torpor of the capillaries of the skin, and of the heart and

arteries by direct sympathy with them; and afterwards of an orgasm or

increased action of the capillaries of the skin, with a decreased action,

or continued torpor, of the heart and arteries by reverse sympathy with

them. This orgasm of the cutaneous capillaries, which appears by the blush

and heat of the skin, is at first owing to the accumulation of the

sensorial power of irritation during their previous torpid state, as in the

febris irritata above described; but which is afterwards supported or

continued by the reverse sympathy of these capillaries with the torpid

state of the heart and arteries, as will be further explained in article 8

of this Supplement.

4. The renovated activity of the capillaries commences as soon or sooner

than that of the heart and arteries after the cold fit of irritative fever;

and is not owing to their being forced open by the blood being impelled

into them mechanically, by the renovated action of the heart and arteries;

for these capillaries of the skin have greater mobility than the heart and

arteries, as appears in the sudden blush of shame; which may be owing to

their being more liable to perpetual varieties of activity from their

exposure to the vicissitudes of atmospheric heat. And because in

inirritative fevers, or those with arterial debility, the capillaries

acquire increased strength, as is evinced by the heat of the skin, while

the pulsations of the heart and arteries remain feeble.

5. It was said above, that the cutaneous capillaries, when they were

rendered torpid by exposure to cold, either recovered their activity by the

reapplication of external warmth; or by their increased irritability, which

is caused by the accumulation of that sensorial power during their

quiescence. An example of the former of these may be seen on emerging from

a very cold bath; which produces a fit of simple fever; the cold fit, and

consequent hot fit, of which may be prolonged by continuing in the bath;

which has indeed proved fatal to some weak and delicate people, and to

others after having been much exhausted by heat and exercise. See Sect.

XXXII. 3. 2. An example of the latter may be taken from going into a bath

of about eighty degrees of heat, as into the bath at Buxton, where the

bather first feels a chill, and after a minute becomes warm, though he

remains in the same medium, owing to the increase of irritability from the

accumulation of that sensorial power during the short time, which the

chilness continued.

6. Hence simple fevers are of two kinds; first, the febris irritativa, or

fever with strong pulse; which consists of a previous torpor of the heart,

arteries, and capillaries, and a succeeding orgasm of those vessels.

Secondly, the febris inirritativa, or fever with weak pulse, which consists

of a previous torpor of the heart, arteries, and capillaries; and of a

succeeding orgasm of the capillaries, the torpor of the heart and arteries

continuing. But as the frequency of the pulse occurs both in the state of

torpor, and in that of orgasm, of the heart and arteries; this constitutes

a criterion to distinguish fever from other diseases, which are owing to

the torpor of some parts of the system, as paresis, and hemicrania.

7. The reader will please to observe, that where the cutaneous or pulmonary

capillaries are mentioned, their mucous and perspirative glands are to be

understood as included; but that the absorbents belonging to those systems

of vessels, and the commencement of the veins, are not always included; as

these are liable to torpor separately, as in anasarca, and petechiae; or to

orgasm, or increased action, as in the exhibition of strong emetics, or in

the application of vinegar to the lips; yet he will also please to observe,

that an increased or decreased action of these absorbents and veins

generally occurs along with that of the capillaries, as appears by the dry

skin in hot fits of fever; and from there being generally at the same time

no accumulation of venous blood in the cutaneous vessels, which would

appear by its purple colour.

II. _Compound fever._

1. When other parts of the system sympathize with this torpor and orgasm of

the cutaneous capillaries, and of the heart and arteries; the fever-fit

becomes more complicated and dangerous; and this in proportion to the

number and consequence of such affected parts. Thus if the lungs become

affected, as in going into very cold water, a shortness of breath occurs;

which is owing to the collapse or inactivity (not to the active

contraction, or spasm), of the pulmonary capillaries; which, as the lungs

are not sensible to cold, are not subject to painful sensation, and

consequent shuddering, like the skin. In this case after a time the

pulmonary capillaries, like the cutaneous ones, act with increased energy;

the breathing, which was before quick, and the air thrown out at each

respiration in less quantity, and cool to the back of the hand opposed to

it, now becomes larger in quantity, and warmer than natural; which however

is not accompanied with the sensation of heat in the membrane, which lines

the air-vessels of the lungs, as in the skin.

2. One consequence of this increased heat of the breath is the increased

evaporation of the mucus on the tongue and nostrils. A viscid material is

secreted by these membranes to preserve them moist and supple, for the

purposes of the senses of taste and of smell, which are extended beneath

their surfaces; this viscid mucus, when the aqueous part of it is

evaporated by the increased heat of the respired air, or is absorbed by the

too great action of the mucous absorbents, adheres closely on those

membranes, and is not without difficulty to be separated from them. This

dryness of the tongue and nostrils is a circumstance therefore worthy to be

attended to; as it shews the increased action of the pulmonary capillaries,

and the consequent increased heat of the expired air; and may thus

indicate, when colder air should be admitted to the patient. See Class I.

1. 3. 1. The middle part of the tongue becomes dry sooner, and recovers its

moisture later, than the edges of it; because the currents of respired air

pass most over the middle part of it. This however is not the case, when

the dryness of the tongue is owing only to the increased mucous absorption.

When however a frequent cough attends pulmonary inflammation, the edges of

the tongue are liable to be as much furred as the middle of it; as during

the action of coughing the middle of the tongue is depressed, so as to form

half a cylinder, to give a greater aperture for the emission of air from

the larynx; and the edges of it become thus as much exposed to the currents

of air, as the middle parts of it.

3. When the internal capillaries or glands sympathize with the cutaneous

capillaries; or when any of them are previously affected with torpor, and

the external or cutaneous capillaries are affected secondarily; other

symptoms are produced, which render the paroxysms of fever still more

complicate. Thus if the spleen or pancreas are primarily or secondarily

affected, so as to be rendered torpid or quiescent, they are liable to

become enlarged, and to remain so even after the extinction of the

fever-fit. These in some intermittent fevers are perceptible to the hand,

and are called ague-cakes; their tumour seems to be owing to the permanent

torpor of the absorbent system, the secerning vessels continuing to act

some time afterwards. If the secretory vessels of the liver are affected

first with torpor, and afterwards with orgasm, a greater secretion of bile

is produced, which sometimes causes a diarrhoea. If a torpor of the

kidneys, and of the absorbents of the bladder occurs, either primarily, or

by sympathy with the cutaneous capillaries, the urine is in small quantity

and pale, as explained in Class I. 2. 2. 5.; and if these secretory vessels

of the kidneys, and the absorbents of the bladder act more strongly than

natural afterwards by their increased irritability or associability, the

urine becomes in larger quantity, and deeper coloured, or deposits its

earthy parts, as in Class I. 1. 2. 4. which has been esteemed a favourable

circumstance. But if the urine be in small quantity, and no sediment

appears in it, after the hot fit is over; it shews, that the secerning

vessels of the kidneys and the absorbent vessels of the bladder have not

regained the whole of their activity, and thence indicates a greater

tendency to a return of the cold fit.

4. When the stomach is affected with torpor either primarily; or

secondarily by its sympathy with the cutaneous capillaries; or with some

internal viscus; sickness occurs, with a total want of appetite to any

thing solid; vomiting then supervenes, which may often be relieved by a

blister on the skin, if the skin be cool and pale; but not if it be hot and

flushed. The intestines cease to perform their office of absorption from a

similar torpor; and a diarrhoea supervenes owing to the acrimony of their

putrid, or of their acid contents. The loose undigested or fetid stools

indicate the inability of the intestines to perform their proper office; as

the mucus and gastric acid, which are vomited up, does that of the stomach;

this torpor of the stomach is liable to continue after the cold paroxysm

ceases, and to convert intermittent fevers into continued ones by its

direct sympathy with the heart and arteries. See article 10 of this

Supplement.

5. If the meninges of the brain sympathize with other torpid parts, or are

primarily affected, delirium, stupor, and perhaps hydrocephalus internus

occur, see Class II. 1. 7. 1. and I. 2. 5. 10; and sometimes the pulse

becomes slow, producing paresis instead of fever. But if the membranes,

which cover the muscles about the head, or of the pericranium, become

torpid by their sympathy with other torpid parts, or are primarily

affected, a head-ach supervenes; which however generally ceases with the

cold paroxysm of fever. For as when the sensorial power of volition is

exhausted by labour, a few hours, or half a solar day, passed in sleep

recruits the system by accumulation of this sensorial power; so when the

sensorial power of irritation is exhausted, one or two solar or lunar days

of rest or quiescence of the affected part will generally restore its

action by accumulation of irritability, and consequent increase of

association, as in hemicrania, Class IV. 2. 2. 8. But when the heart and

arteries become torpid, either primarily, or by their sympathy with the

stomach, this accumulation of the sensorial power of irritation can take

place but slowly; _as to rest is death_! This explains the cause of the

duration of fevers with weak pulse, which continue a quarter, or half, or

three quarters, or a whole lunation, or still longer, before sufficient

accumulation of irritability can be produced to restore their natural

strength of action.

6. If the absorbent vessels, which are spread around the neck of the

bladder, become torpid by their direct sympathy with the absorbents of the

skin in cold fits of fever; the urine, which is poured into the bladder in

but small quantity from the torpid kidneys, has nevertheless none of its

aqueous saline part reabsorbed; and this saline part stimulates the bladder

to empty itself frequently, though the urine is in small quantity. Which is

not therefore owing to any supposed spasm of the bladder, for the action of

it in excluding the urine is weak, and as much controlable by the will as

in ordinary micturition.

7. If the beginnings or absorbent mouths of the venous system remain

torpid, petechiae or vibices are produced in fevers, similar to those which

are seen in scurvy without fever. If the skin was frequently moistened for

an hour, and at the same time exposed to the common air, or to oxygen gas,

it might contribute to turn the black colour of these points of

extravasated blood into scarlet, and thus by increasing its stimulus

facilitate its reabsorption? For oxygen gas penetrates moist animal

membranes though not dry ones, as in the lungs during respiration.

8. When the sensorial power of sensation is introduced into the arterial

system, other kinds of compound fevers are produced, which will be spoken

of in their place.

III. _Termination of the cold Fit._

1. If all the parts, which were affected with torpor, regain their

irritability, and associability, the cold paroxysm of fever ceases; but as

some of the parts affected were previously accustomed to incessant action,

as the heart and arteries, and others only to intermitted action, as the

stomach and intestines; and as those, which are subjected during health to

perpetual action, accumulate sensorial power faster, when their motions are

impeded, than those which are subjected to intermitted action; it happens,

that some of the parts, which were affected with torpor during the cold

fit, recover their irritability or associability sooner than others, and

more perfectly, or acquire a greater quantity of them than natural; as

appears by the partial heat and flushings previous to the general hot fit.

Hence if all the parts, which were previously torpid, regain their due

degree of irritability, or of associability, the disease is removed, and

health restored. If some or all of them acquire more than their natural

degree of these sensorial powers; increased actions, and consequent

increased secretions, and greater heat occur, and constitute the hot fit of

fever. If after this hot fit of fever all the parts, which had acquired too

great irritability, or associability, regain their natural degree of it;

the disease is removed, and health restored. But if some of these parts do

not regain their natural degree of these sensorial powers, the actions of

those parts remain imperfect, and are more or less injurious to the system,

according to the importance of their functions.

2. Thus if a torpor of the heart and arteries remains; the quick pulse

without strength, which began in the cold fit, persists; and a continued

fever is produced. If the torpor of the stomach and intestines remains,

which are known by sickness and undigested stools, the fever is liable to

be of considerable length and danger; the same if the kidnies and absorbent

system retain some degree of torpor, as is shewn by the pale urine in not

unusual quantity. If part of the absorbent system remains torpid, as the

absorbent vessels of the spleen, a tumour of that viscus occurs, which may

be felt by the hand; the same sometimes happens to the liver; and these

from their tendency to more complete torpor are afterwards liable to give

occasion to a return of the cold fit. If the cellular absorbents do not

completely recover their activity, a pale and bloated countenance with

swelled legs mark their want of action.

3. As the termination of the cold fit is owing to the accumulation of the

sensorial power of irritation and of association during the previous

quiescence of the system; and as those parts, which are in perpetual action

during health, are more subject to this accumulation during their torpor,

or quiescence; one should have imagined, that the heart and arteries would

acquire this accumulation of sensorial power sooner or in greater degree

than other parts. This indeed so happens, where the pulse is previously

strong, as in febris irritativa; or where another sensorial power, as that

of sensation, is exerted on the arterial system, as in inflammations. The

heart and arteries in these cases soon recover from their torpor, and are

exerted with great violence.

Many other parts of the system subject to perpetual motion in health may

rest for a time without much inconvenience to the whole; as when the

fingers of some people become cold and pale; and during this complete rest

great accumulation of irritability may be produced, But where the heart and

arteries are previously feeble, they cannot much diminish their actions,

and certainly cannot rest entirely, for that would be death; and therefore

in this case their accumulation of the sensorial power of irritation or of

association is slowly produced, and a long fever supervenes in consequence;

or sudden death, as frequently happens, terminates the cold fit.

Whence it appears, that in fevers with weak pulse, if the action of the

heart, arteries, and capillaries could be diminished, or stopped for a

short time without occasioning the death of the patient, as happens in cold

bathing, or to persons apparently drowned, that a great accumulation of the

sensorial powers of irritation or of association might soon be produced,

and the pulse become stronger, and consequently slower, and the fever

cease. Hence cold ablution may be of service in fevers with weak pulse, by

preventing the expenditure and producing accumulation of the sensorial

power of irritation or association. Stupor may be useful on the same

account. Could a centrifugal swing be serviceable for this purpose, either

by placing the head or the feet in the outward part of the circle, as

described in Art. 15. 7. of this Supplement?

IV. _Return of the cold Fit._

1. If the increased action of the cutaneous and pulmonary capillaries, and

of the heart and arteries, in febris irritativa continues long and with

violence, a proportional expenditure or exhaustion of sensorial power

occurs; which by its tendency to induce torpor of some part, or of the

whole, brings on a return of the cold fit.

2. Another cause which contributes to induce torpor of the whole system by

the sympathy of its parts with each other, is the remaining torpor of some

viscus; which after the last cold paroxysm had not recovered itself, as of

the spleen, liver, kidnies, or of the stomach and intestines, or absorbent

vessels, as above mentioned.

3. Other causes are the deficiency of the natural stimuli, as hunger,

thirst, and want of fresh air. Other causes are great fatigue, want of

rest, fear, grief, or anxiety of mind. And lastly, the influence of

external ethereal fluids, as the defect of external heat, and of solar or

lunar gravitation. Of the latter the return of the paroxysms of continued

fevers about six o'clock in the evening, when the solar gravitation is the

least, affords an example of the influence of it; and the usual periods of

intermittents, whether quotidian, tertian, or quartan, which so regularly

obey solar or lunar days, afford instances of the influence of those

luminaries on these kinds of fevers.

4. If the tendency to torpor of some viscus is considerable, this will be

increased at the time, when the terrene gravitation is greatest, as

explained in the introduction to Class IV. 2. 4. and may either produce a

cold paroxysm of quotidian fever; or it may not yet be sufficient in

quantity for that purpose, but may nevertheless become greater, and

continue so till the next period of the greatest terrene gravitation, and

may then either produce a paroxysm of tertian fever; or may still become

greater, and continue so till the next period of greatest terrene

gravitation, and then produce a paroxysm of quartan ague. And lastly, the

periodical times of these paroxysms may exceed, or fall short of, the time

of greatest diurnal terrene gravitation according to the time of day, or

period of the moon, in which the first fit began; that is, whether the

diurnal terrene gravitation was then in an increasing or decreasing state.

V. _Sensation excited in Fever._

1. A curious observation is related by Dr. Fordyce in his Tract on Simple

fever, page 168. He asserts, that those people, who have been confined some

time in a very warm atmosphere, as of 120 or 130 degrees of heat, do not

feel cold, nor are subject to paleness of their skins, on coming into a

temperature of 30 or 40 degrees; which would produce great paleness and

painful sensation of coldness in those, who had been some time confined in

an atmosphere of only 86 or 90 degrees. Analogous to this, an observing

friend of mine assured me, that once having sat up to a very late hour with

three or four very ingenious and humorous companions, and drank a

considerable quantity of wine; both contrary to his usual habits of life;

and being obliged to rise early, and to ride a long journey on the next

day; he expected to have found himself weak and soon fatigued; but on the

contrary he performed his journey with unusual ease and alacrity; and

frequently laughed, as he rode, at the wit of the preceding evening. In

both these cases a degree of pain or pleasure actuated the system; and thus

a sensorial power, that of sensation, was superadded to that of irritation,

or volition. See Sect. XXXIV. 2. 6.

2. Similar to this, when the energetic exertions of some parts of the

system in the hot fit of fever arise to a certain excess, a degree of

sensation is produced; as of heat, which particularly increases the actions

of the cutaneous vessels, which are more liable to be excited by this

stimulus. When this additional sensorial power of sensation exists to a

greater degree, the pulse, which was before full, now becomes hard, owing

to the inflammation of the vasa vasorum, or coats of the arteries. In these

cases, whether there is any topical inflammation or not, the fever ceases

to intermit; but nevertheless there are daily remissions and exacerbations

of it; which recur for the most part about six in the evening, when the

solar gravitation is the least, as mentioned in Sect. XXXVI. 3. 7.

3. Thus the introduction of another sensorial power, that of sensation,

converts an intermittent fever into a continued one. If it be attended with

strong pulse, it is termed febris sensitiva irritata, or pyrexia, or

inflammation; if with a weak pulse, it is termed febris sensitiva

inirritata, or typhus gravior, or malignant fever. The seat of the

inflammation is in the glandular or capillary system, as it consists in the

secretion of new fluids, or new fibres, which form new vessels, as they

harden, like the silk of the silk-worm. See Art. 15. of this Supplement.

VI. _Circles of irritative Associate Motions._

1. There are some associate motions, which are perpetually proceeding in

our waking hours, and are catenated by their first link, or in some

subsequent parts of the chain, with the stimuli or the influence of

external things; which we shall here enumerate, as they contribute to the

knowledge of fever. Of these are the irritative ideas, or sensual motions

of the organs of sense, and the muscular motions associated with them;

which, when the chain is disturbed or interrupted, excite the sensorial

power of sensation, and proceed in confusion. Thus if the irritative ideas

of sight are disturbed, the paralactic motions of objects, which in general

are unperceived, become sensible to us; and the locomotive muscles

associated with them, which ought to preserve the body erect, stagger from

this decrease or interruption of the sensorial power of association; and

vertigo is produced.

When the irritative sensual motions, or ideas, belonging to one sense are

increased or diminished, the irritative sensual motions, or ideas, of the

other senses are liable to become disturbed by their general catenations;

whence occur noises in the ears, bad tastes in the mouth, bad odours, and

numbness or tingling of the limbs, as a greater or less number of senses

are affected. These constitute concomitant circles of disturbed irritative

ideas; or make a part of the great circle of irritative ideas, or motions

of the organs of sense; and when thus disturbed occasion many kinds of

hallucination of our other senses, or attend on the vertigo of vision.

2. Another great circle of irritative associated motions consists of those

of the alimentary canal; which are catenated with stimuli or with

influences external to the system, but continue to be exerted in our

sleeping as well as in our waking hours. When these associations of motion

are disturbed by the too great or too small stimulus of the food taken into

the stomach, or by the too great excess or deprivation of heat, or by

indigestible substances, or by torpor or orgasm occasioned by their

association with other parts, various diseases are induced under the names

of apepsia, hypochondriasis, hysteria, diarrhoea, cholera, ileus,

nephritis, fever.

3. A third circle of irritative associate motions consists of those of the

absorbent system; which may be divided into two, the lacteals, and the

lymphatics. When the stomach and intestines are recently filled with food

and fluid, the lacteal system is stimulated into great action; at the same

time the cellular, cutaneous, and pulmonary lymphatics act with less

energy; because less fluid is then wanted from those branches, and because

more sensorial power is expended by the lacteal branch. On this account

these two systems of absorbents are liable to act by reverse sympathy;

hence pale urine is made after a full dinner, as less of the aqueous part

of it is imbibed by the urinary lymphatics; and hence the water in anasarca

of the lungs and limbs is speedily absorbed, when the actions of the

lacteals of the stomach or intestines are weakened or inverted by the

exhibition of those drugs, which produce nausea, or by violent vomiting, or

violent cathartics.

Hence in diabetes the lacteal system acts strongly, at the same time that

the urinary lymphatics invert their motions, and transmit the chyle into

the bladder; and in diarrhoea from crapula, or too great a quantity of food

and fluid taken at a time, the lacteals act strongly, and absorb chyle or

fluids from the stomach and upper intestines; while the lymphatics of the

lower intestines revert their motions, and transmit this over-repletion

into the lower intestines, and thus produce diarrhoea; which accounts for

the speedy operation of some cathartic drugs, when much fluid is taken

along with them.

4. Other circles of irritative associate motions of great importance are

those of the secerning system; of these are the motions of the larger

congeries of glands, which form the liver, spleen, pancreas, gastric

glands, kidneys, salivary glands, and many others; some of which act by

direct and others by reverse sympathy with each other. Thus when the

gastric glands act most powerfully, as when the stomach is filled with

food, the kidneys act with less energy; as is shewn by the small secretion

of urine for the first hour or two after dinner; which reverse sympathy is

occasioned by the greater expenditure of sensorial power on the gastric

glands, and to the newly absorbed fluids not yet being sufficiently

animalized, or otherwise prepared, to stimulate the secretory vessels of

the kidneys.

But those very extensive glands, which secrete the perspirable matter of

the skin and lungs, with the mucus, which lubricates all the internal cells

and cavities of the body, claim our particular attention. These glands, as

well as all the others, proceed from the capillary vessels, which unite the

arteries with the veins, and are not properly a part of them; the mucous

and perspirative glands, which arise from the cutaneous and pulmonary

capillaries, are associated by direct sympathy; as appears from immersion

in the cold bath, which is therefore attended with a temporary difficult

respiration; while those from the capillaries of the stomach and heart and

arteries are more generally associated by reverse sympathy with those of

the cutaneous capillaries; as appears in fevers with weak pulse and

indigestion, and at the same time with a hot and dry skin.

The disturbed actions of this circle of the associate motions of the

secerning system, when the sensorial power of sensation is added to that of

irritation, frequently produces inflammation, which consists in the

secretion of new fluids or new vessels. Nevertheless, if these disturbed

actions be of the torpid kind, the pain, which attends them, is seldom

productive of inflammation, as in hemicrania; but is liable to excite

voluntary actions, and thus to expend much sensorial power, as in the

shuddering in cold fits of fever, or in convulsions; or lastly the pain

itself, which attends torpid actions, is liable to expend or exhaust much

sensorial power without producing any increased actions; whence the low

pulse, and cold extremities, which usually attend hemicrania; and hence

when inert, or inactive sensation attends one link of associated action,

the succeeding link is generally rendered torpid, as a coldness of the

cheek attends tooth-ach.

5. A fifth important circle of irritative motions is that of the

sanguiferous system, in which the capillary vessels are to be included,

which unite the arterial and venous systems, both pulmonary and aortal. The

disturbed action of this system of the heart and arteries, and capillaries,

constitute simple fever; to which may be added, that the secerning and

absorbent vessels appending to the capillaries, and the bibulous mouths of

the veins, are in some measure at the same time generally affected.

6. Now, though the links of each of these circles of irritative motions are

more strictly associated together, yet are they in greater or less degree

associated or catenated with each other by direct or reverse sympathy. Thus

the sickness, or inverted irritative motions of the stomach, are associated

or catenated with the disturbed irritative ideas, or sensual motions, in

vertigo; as in sea-sickness. This sickness of the stomach is also

associated or catenated with the torpor of the heart and arteries by direct

sympathy, and with the capillaries and absorbents by reverse sympathy; and

are thus all of them liable occasionally to be disturbed, when one of them

is diseased; and constitute the great variety of the kinds or symptoms of

fevers.

VII. _Alternation of the cold and hot Fits._

1. When any cause occurs, which diminishes to a certain degree the supply

of sensorial power in respect to the whole system; as suppose a temporary

inexertion of the brain; what happens? First, those motions are exerted

with less energy, which are not immediately necessary to life, as the

locomotive muscles; and those ideas, which are generally excited by

volition; at the same time this deficiency of voluntary motion is different

from that which occurs in sleep; as in that the movements of the arterial

system are increased in energy though not in frequency. Next, the motions

of the alimentary canal become performed with less energy, or cease

altogether; and a total want of appetite to solid food occurs, or sickness,

or a diarrhoea occasioned by the indigested aliment. Then the absorbent

vessels cease to act with their due energy; whence thirst, and pale urine,

though in small quantities. Fourthly, the secerning vessels become affected

by the general diminution of sensorial power; whence all the secreted

fluids are produced in less quantity. And lastly, the sanguiferous canals

feel the general torpor; the pulsations of the heart and arteries become

feeble, and consequently quick; and the capillaries of the skin become

inactive, acquire less blood from the arteries, and are consequently paler

and shrunk.

In this last circumstance of the torpor of the sanguiferous system consists

inirritative fever; as all the others are rather accidental or concomitant

symptoms, and not essential ones; as fewer or more of them may be present,

or may exist with a greater or less degree of inactivity.

2. Now as the capillaries of the skin are exposed to greater varieties of

heat and cold, than the heart and arteries, they are supposed to be more

mobile, that is, more susceptible of torpor or exertion, or to

inflammation, by external stimuli or influences, than the other parts of

the sanguiferous system; and as the skin is more sensible to the presence

of heat, than the internal parts of the body, the commencement of the cold

paroxysms of fever generally either first exists in, or is first perceived

by, the coldness and paleness of the skin; and the commencement of the hot

fits by the heat and redness of it.

Zoonomia; Or, the Laws of Organic Life, Vol. II · 第 10 / 14 章