The diet in the early actively febrile stage should consist of panada,

corn-meal or oat-meal gruel, milk, and barley-water, or even pure milk.

Where persons will not take milk the various thin animal broths to

which good barley-water or arrowroot or well-boiled rice has been

added, jellies, sago and other starchy puddings, may be allowed.

Suitable drinks are--plain water, Seltzer and Apollinaris water,

carbonic-acid water, lemonade. This low, unstimulating diet should be

observed until all fever and articular inflammation have subsided, the

tongue become clean, and the visceral inflammations declined, and a

return to solid food, and especially to animal food, should be made

cautiously. Eggs are to be regarded as of very doubtful safety in this

disease. As a very general rule, ales, wines, and the stronger

alcoholic liquids are objectionable, but they may be required under the

same conditions as in other fevers. Should the salicylates depress the

heart, old wine or whiskey may be given with advantage.

During convalescence the patient should not be permitted to leave his

bed for several days after complete removal of the fever and articular

pain, and for the first four days he should occupy a sofa or

easy-chair. Premature walking may induce relapse. An occasional

alkaline or sulphur bath, if cautiously taken, sometimes appears to

complete the recovery. If endocarditis have existed, a longer rest is

desirable, more especially in severe cases, in order that the

reparative process going on in the lately inflamed valves may not be in

the least disturbed.

Chronic Articular Rheumatism,

synonymous with rheumarthritis chronica, rheumatisme articulaire

chronique simple (Besnier), polyarthritis synovialis chronica (Heuter),

is defined here as a chronic idiopathic inflammation of one or a few

articulations, which is more prone to become fixed than the acute form,

and which, notwithstanding its protracted duration, produces no

profound structural alterations in the joints.

ETIOLOGY.--It may be the direct sequel of a single attack or more {70}

commonly of several attacks, of acute, or more especially of subacute,

articular rheumatism. But it is generally a primary affection,

occurring in persons who have not had either acute or subacute

rheumarthritis, yet owning the same causation as these, and

occasionally in its course exhibiting acute or subacute symptoms. The

specially predisposing conditions are inheritance; repeated attacks of

subacute or acute articular rheumatism, which in accordance with

general laws impair the resisting power of the affected joints;

prolonged residence or employment in cold, damp, or wet rooms or

localities; repeated exposure to bleak, cold currents of air or to

frequent wettings of the body or lower limbs. For these reasons it is

most common amongst the poor, who are especially exposed to the

influences just mentioned; and amongst them cellar-men and sailors,

washerwomen and maid-servants, are very liable to the disease. It is

chiefly an affection of advanced life, or at least of mid-age, and is

rare in youth. The first attacks, and especially exacerbations, are apt

to be induced by the direct action of a draught of cold air or by

unusual exposure to cold and damp air, especially when the body has

been fatigued or overheated. In many cases no distinct exciting cause

can be traced.

The morbid anatomy of simple chronic articular rheumatism will vary

with the severity and duration of the disease. The alterations are such

as chronic inflammation of a non-suppurative character might be

expected to produce in the joints by one who had learned those

characteristic of acute rheumarthritis. In the simple chronic form the

proliferating process involves chiefly the synovial membrane, the

capsular and other ligaments, and the periarticular tissues; to a less

degree the cartilages, and to a much less degree, and exceptionally,

the osseous surfaces. The synovial membrane is thickened, slightly

injected, and its fringes hypertrophied and more vascular than

normally. Little fluid usually exists in the joint unless during an

exacerbation, when a moderate amount of thin, cloudy serum may be

present; generally only a trace of thick, turbid fluid, containing

oil-globules, and in severe cases débris of the cartilages, but no pus,

is found. The fibrous capsule and ligaments become thickened, dense,

and stiffened by hyperplasia; and sometimes the adjacent tendons and

their sheaths, the fasciæ and aponeuroses, undergo similar alterations,

so that the movements of the joints become seriously interfered with.

In some cases this irritative hyperplasia specially involves these

periarticular fibrous structures, and these, undergoing retraction,

produce marked deviations, subluxations, and deformities of the

articulations very like those observed in rheumatoid arthritis,

although the osseous components of the joints are unaffected. Jaccoud

gave to such cases the title of chronic fibrous rheumatism.[211] It is

worth noting that Jaccoud's, Charcot's,[212] and Rinquet's[213] cases

of so-called "chronic fibrous rheumatism" developed out of acute

articular rheumatism, while Besnier's was primarily chronic. In simple

chronic rheumatism, if protracted, the cartilages also proliferate,

lose their semi-transparency and polish, and become opaque and white;

they are often rough and traversed by fissures, and occasionally

present erosions; and these erosions {71} are either naked or covered

with a layer of newly-formed connective tissue, which may occasionally

produce fibrous adhesions between the articular surfaces. Points of

calcification occur in the cartilages and tendons in very chronic

cases. Instances are observed in which the bones exhibit, to a slight

degree, the alterations found in rheumatoid arthritis, and are probably

transitional between the two affections. The muscles which move the

affected articulations in severe cases are often atrophied, and the

wasting imparts to the joints an appearance of considerable

enlargement.

[Footnote 211: Vide Jaccoud, _Clin. Méd. de la Charité_, 23e Leçon,

Paris, 1867.]

[Footnote 212: Besnier, _Dictionnaire Encyclopéd., etc._, t. iv., p.

680 _et seq._]

[Footnote 213: _Du Rheum. Artic. Chronique, etc._, par Martial Rinquet,

Thèse, Paris, 1879, pp. 28-33.]

SYMPTOMS AND COURSE.--Simple chronic articular rheumatism presents many

varieties. In the milder forms the patient experiences trifling or

severe pain in one, or less frequently in two or more, joints, more

especially in the knee or shoulder, or both, attended with want of

power in the member or with stiffness in the affected articulation. The

pain frequently is likewise felt in the soft parts, muscular and

tendinous, near the joints, and is usually increased by active or

passive movement; it is not always accompanied by tenderness, and

rarely with local elevation of temperature or swelling. The wearying

aching in the joint is of an abiding character, but is very liable to

exacerbations, especially at night; and these come on just before

atmospheric changes, such as a considerable fall of temperature, the

approach of rain, variations in the direction of the wind, etc., and

they usually continue as long as the weather remains cold and wet. A

very common symptom is a creaking or a grating which may be felt and

heard during the movements of the joint.

The above symptoms may rarely prove more or less constant by night and

day for years, but far more frequently, at least at first, they last an

indefinite period and disappear to recur again and again, especially in

the cold and changeable seasons of the year. Although in the earlier

attacks, and often for a long time, no alteration of structure is

perceptible in the painful joints, yet in some instances slight

effusion into the articulation may be observed during the

exacerbations, or the capsule and ligaments may at length become

slightly thickened, or the muscles may waste and produce an apparent

enlargement of the joint; and this prominence of the articular surfaces

may be increased by retraction of the tendons and aponeuroses--a

condition which causes real deformities (deviations, subluxations,

etc.) of the articulation and impairs more or less its movements. In

very chronic cases a fibrous ankylosis may be established.

These last-mentioned conditions often entail great and long-continued

suffering, and may even cause some anæmia and general debility; but

very frequently the general health and vigor continue good,

notwithstanding the permanent impairment of the functions of one or

several of the large articulations, and the liability to exacerbations

often amounting to attacks of subacute rheumarthritis from changes in

the weather, fatigue, or exposure.

Besides the above varieties may be mentioned a not infrequent one

consisting of a series of attacks of subacute articular rheumatism

recurring at short intervals, involving the same joints, and attended

with slight elevation of temperature, febrile urine, perspiration, and

moderate local evidences of synovitis, heat, pain, tenderness,

swelling, and effusion into the affected joints. This is an obstinate

variety, and is often associated with rheumatic pain in the muscles and

fibrous tissues of the affected member.

{72} Simple chronic articular rheumatism, like the acute form, is most

apt to affect the larger articulations, knees, shoulders, etc., but it

frequently also involves the smaller ones of the hands and feet.

Although usually polyarticular, it is prone to become fixed in a single

joint, but even then it may attack several other articulations, and may

migrate from one to another without damaging any.

The course of the disease is usually one of deterioration during

persistent or recurring attacks, and in many cases the intervals of

relief become shorter and less marked; the joints become weaker and

stiffer; and although the pain may not increase and the general health

may not be seriously impaired, yet the patients may continue for many

years or the rest of their lives severe sufferers, unable to work, and

often hardly able to walk even with the aid of a stick. Occasionally,

after several years of pain and weakness, a sudden or slow improvement

may set in and the patient become free from pain and lameness, and only

experience some stiffness in the movements of the joints after several

hours of rest, and slight thickening of the ligaments and capsule of

one or more articulations. The duration of the disease is indefinite;

the danger to life trifling.

The complications of simple chronic articular rheumatism are held by

many, and especially by those who regard the disease as constitutional

or diathetic, to be the same as those of the acute form, and that they

may precede, follow, alternate, or occur simultaneously with the

articular affection. All admit that they are observed much less

frequently in the former than in the latter. Other pathologists either

deny the occurrence of the visceral complications (Senator, Flint) or

do not mention them (Niemeyer). It is not denied that cardiac disease

may be found in chronic articular rheumatism which has succeeded the

acute form, and which may then be referred to the acute attack. The

tissue-changes then set up may not have produced at the time the

murmurs indicative of endocarditis, but these tissue-changes may have

ultimately roughened the endocardium, puckered a valve, or shortened

its cords, so that cases of chronic articular rheumatism having a

history of an acute attack cannot be safely included when inquiring

into the influence of the chronic form upon the heart or other internal

organ. Attention has not been sufficiently given to ascertain the

frequency of the occurrence of these complications in primary chronic

articular rheumatism, and reliable evidence is not at hand. It is not

unlikely that the chronic form may slowly develop cardiac changes, as

the acute form rapidly does; but when the advanced age of the persons

most liable to chronic rheumatism is borne in mind, it must be admitted

that valvular and arterial lesions (endarteritis) are observed at such

periods of life independently of rheumatism, and referable to such

causes as repeated muscular effort, strain, chronic Bright's disease,

senile degeneration, etc. Somewhat similar observations are applicable

to the attacks of asthma, of subacute bronchitis, of neuralgia, and of

dyspepsia, which are frequently complained of by sufferers from simple

chronic rheumarthritis. Such affections are common in elderly people in

cold and damp climates; they may be mere complications rather than

manifestations of rheumatism, or outcomes of the confinement and its

attendant evils incident to chronic articular rheumatism, as is

probably the relationship of the dyspepsia. There is {73} no doubt of

the frequent coexistence of muscular rheumatism with this variety.

DIAGNOSIS.--Simple chronic articular rheumatism may be confounded with

rheumatoid arthritis, with the articular affections of locomotor ataxia

and other spinal diseases, with chronic articular gout, with syphilitic

and with strumous disease of the joints. The reader may consult the

observations made on four of these affections in connection with the

diagnosis of rheumatoid arthritis. A few additional remarks are called

for in distinguishing chronic articular rheumatism from chronic

articular gout, which is often a very difficult problem. Both are apt

to be asymmetrical in distribution, to have paroxysmal exacerbations,

to recur frequently without damaging the articulations, to have been

preceded by acute attacks of their respective affections, and to be

uncomplicated by endo- or pericarditis. But chronic rheumarthritis has

no special tendency to attack the great toe; it is more persistent than

gouty arthritis; it does not, even when of long standing, produce the

peculiar deformities of the articulations or the visible chalk-like

deposits in the ears or fingers observed in chronic gout. The etiology

of the two diseases is dissimilar. There is no special liability to

interstitial nephritis in articular rheumatism, nor is urate of soda

present in the blood in that disease.

In chronic strumous or tubercular disease of a joint the youth, the

personal and family history, and sometimes the evident defective

nutrition, of the patient; the moderate degree of local pain compared

with the considerable progressive and uniform enlargement of the joint;

the evident marked thickening of the synovial membrane, either early or

late according as the disease has originated in the synovial membrane

or in the bones; the continuous course, without marked remissions or

exacerbations, of the disease; the rarity with which more than one

joint is affected; and the tendency to suppuration, ulceration, marked

deformity, and final destruction of the joint,--will prevent the

disease from being mistaken for chronic rheumatism.

The PROGNOSIS in simple chronic rheumarthritis is unfavorable as

regards complete recovery, and it is chiefly while comparatively

recent, and when the sufferer can be removed from the conditions

productive of the disease, that permanent improvement, and sometimes

cure, may be expected. As a rule, the disease once established recurs.

It does not, however, endanger life.

TREATMENT.--All are agreed that hygienic treatment constitutes an

essential, if not the most valuable, part of the curative and

palliative management of chronic rheumarthritis. A dry and uniform

climate is the most suitable, and there is much evidence in favor of a

dry and warm rather than a dry and cold climate. Protection of the body

against cold and damp by means of flannel next the skin, sufficient

clothing, residence in dry and warm houses, etc., is of prime

importance. In fact, all the known or suspected causes of the disease

should be as far as possible removed.

The direct treatment of the disease resolves itself into general and

local, and is essentially the same as that recommended for rheumatoid

arthritis, to which subject the reader is referred. A few observations

only need be made here. Although, like everything else in chronic

rheumarthritis, it often fails, no single remedy has in the writer's

{74} experience afforded so much relief to the pain and stiffness of

the joints as the sodium salicylate; and he cites with pleasure the

confirmatory testimony of J. T. Eskridge of Philadelphia,[214] of whose

28 cases 75 per cent. were decidedly benefited. Jacob of Leeds also

reports some benefit in 75 per cent. out of 87 cases treated by the

same agent.[215] It must be given in full doses, and be persevered

with. Salicylate of quinia should be tried if there be much debility or

if the sodium salt fail. Propylamine or trimethylamine is deserving of

further trial in this disease. From 100 to 200 grains are given in the

day in peppermint-water. Iodide of potassium, cod-liver oil, arsenic,

iodide of iron, and quinia are all and several remedies from which more

or less benefit is derived in chronic articular rheumatism. The

combination of iodide of potassium with guiaiac resin--gr. ij-iij of

each three times a day in syrup and cinnamon-water--is sometimes very

useful. The writer has no experience of the bromide of lithium

(Bartholow). When the skin is habitually dry and harsh a dose of

pilocarpine every other night for a few times will often prove very

useful.

[Footnote 214: _Phila. Med. Times_, vol. ix. pp. 75-77, 1878, and _The

Medical Bulletin_, Phila., July, 1879, pp. 44-48.]

[Footnote 215: _Brit. Med. Jour._, ii., 1879, 171.]

Cod-liver oil, iron, quinia, etc., the various forms of baths and

mineral waters, electricity, and the several local measures recommended

for the treatment of rheumatoid arthritis, are all occasionally very

useful in, and constitute the appropriate treatment of, simple chronic

articular rheumatism. The dietetic management of the two affections

should be the same.

Muscular Rheumatism.

SYNONYMS.--Myalgia rheumatica or myopathia; _Fr._ Rheumatisme

musculaire; _Ger._ Muskelrheumatismus.

DEFINITION.--The affections included under this term are certain

painful disorders of fibro-muscular structures. They are commonly found

in persons the subjects of the rheumatic diathesis, and are

characterized by pain and often spasm, and sometimes a slight degree of

fever. No doubt as our knowledge increases so many attacks connected

with painful states of muscles and fasciæ are eliminated from the

somewhat uncertain group of muscular rheumatism. True inflammation is

not believed to exist, and pathological investigation has rarely shown

any morbid changes in the affected parts. The symptoms, therefore, have

been attributed to some temporary hyperæmia, slight serous exudation,

or neuralgic state of the sensory nerve-filaments. The strongest

support is given to this statement from the absence of any marked

tenderness in such affected muscles as can be sufficiently examined. In

certain cases, undistinguishable clinically, it is quite probable that

a periarthritis is in reality the principal factor in the case. In

others, again, a subacute rheumatism affecting a joint seems to spread

to the adjoining tendinous sheaths, and thus secondarily to attack the

muscles themselves, the affection of which may ultimately remain the

only condition present.

ETIOLOGY.--Muscular rheumatism is a very common affection. All ages are

liable to its occurrence, but the part affected varies with the time

{75} of life, children and young adults being much more subject to

torticollis, and older persons to lumbago and general rheumatism of the

limbs. Amongst hospital patients the disease prevails more amongst men

than women, owing doubtless to the greater exposure of the former to

the cold; but amongst other classes the same difference is not seen. It

is observed in all countries, but according to some writers it is

unusually frequent in tropical climates, although there acute

rheumatism is very uncommon. The causes of muscular rheumatism are

mainly exposure to cold and strain or fatigue of muscles. If these two

conditions coexist--_e.g._ standing in a draught of cold air or lying

on the ground when fatigued--the chances of the affection coming are

greatly enhanced. Strain, a twist of the body, or a false step can

actively start an attack of this kind, and by the sufferers themselves

it is constantly attributed to this cause. The part played by this

element is difficult to determine, a very slight strain being often

followed by great pain and distress from the subsequent rheumatic

affection. Some individuals are specially prone to attacks, the

slightest current of air, change of clothing, etc. being sufficient to

determine its occurrence. These persons are often found to have

suffered from rheumatism in some other form, and thus in them we must

consider that the rheumatic diathesis furnishes the reason for their

unusual susceptibility. It only remains to mention the fact that a

disposition to gout seems to favor the development of muscular

rheumatism. In gouty families, therefore, it has been observed to be

common.

SYMPTOMS.--In all cases pain is the prominent, and in many cases the

only, symptom present. In all except the more aggravated attacks pain

is felt only when the affected part is disturbed. In such when complete

rest or fixed immobility is maintained there is comfort, or at most a

somewhat dull, uneasy sensation, but when any contraction of the

muscles in question is produced, whether voluntary or otherwise, severe

often excruciating pain is at once experienced, often giving rise to a

sudden cry or causing the features to be contracted in a grimace. The

suffering ceases almost at once when the muscular contraction is

relaxed. In more aggravated attacks the pain is more severe, and

besides persists, though to a less degree, even when there is no

contraction. In rare cases when the maximum degree has been attained

there is continuous pain, but the affected muscles are persistently

maintained in a relaxed condition by means of true spasm in the

surrounding muscles. Slow passive movement affects the subject of

muscular rheumatism, and may often be accomplished with a little

management without causing pain. If, at the same time, these muscles be

handled by pinching and slight pressure, it will be found that they are

very sensitive to the touch. When some tenderness does exist, it is

slight and is not located in the district of the lower nerve-trunks.

Pressure even sometimes allays pain. The constant effort to avoid pain

gives rise to a feeling and appearance of stiffness, and thus

characteristic attitudes and positions of the head, trunk, or limbs are

voluntarily and persistently maintained. There is no spasm of the

affected muscles; the distortion is the result of stiff contraction of

the associated muscles, which thus forcibly fix the faulty one and hold

it in a state of relaxation. Cramp or spasmodic contraction of a single

muscle of a painful character does, however, sometimes occur in

rheumatic subjects, and much resembles the condition above described.

In {76} the same persons also muscular rheumatism may occur in a much

more fugitive or erratic form, frequently being nothing more than a

slightly painful condition of some group of muscles which have in some

way been exposed to cold. This may last but a short time, and either

spontaneously disappear or be readily removed by exercise or friction.

Muscular rheumatism is generally confined to one muscle or a single

group of muscles. Those most liable to it are the very superficial and

those easily exposed to cold (_e.g._ the deltoid and trapezius),

powerful muscles often subjected to violent strain (_e.g._ the lumbar

muscles), and those aiding in the formation of the parietes of the

great cavities.

This affection very commonly exists without any constitutional

disturbances, but sometimes there are present the symptoms of

pyrexia--slight elevation of temperature and temporary disorder of the

digestive organs--loss of appetite, constipation, and general malaise.

A system of practical medicine. By American authors. Vol. 2 · 第 8 / 184 段