LETTER IV.

It need scarcely be said how much it behooves all medical men to keep

in view the subject of the wide-spreading cholera, and not to suffer

themselves to be led from an attentive consideration of all that

appertains to it, by the great political questions which at present

convulse the whole kingdom.

I totally disagree with Dr. Macmichael, as I believe most people will,

that the notion of _contagion_ in many diseases is "far from being

natural and obvious to the mind;" for, since the time that contagious

properties have been generally allowed to belong to certain diseases,

there has been a strong disposition to consider this as the most natural

and obvious mode of explaining the spreading of other diseases. A person

sees evidence of the transmission, _mediate_ as well as _immediate_,

of small-pox, from one person to another; and, in other diseases, the

origin of which may be involved in obscurity, he is greatly prone

to assign a similar cause which may seem to reconcile things so

satisfactorily to his mind. Indeed there seems, in many parts of the

world, a degree of _popularity_ as to quarantine regulations, which

is well understood and turned to proper account by the initiated in

the mysteries of that department:--for what more common than the

expression--"we cannot be too careful in our attempts to _keep out_

such or such a disease?" For my part, I admit that I can more easily

comprehend the propagation of certain epidemics by contagion, than I

can by any other means, _when unaccompanied by sensible atmospheric

changes_; and if I reject contagion in cholera, it is because whatever

we have in the shape of fair evidence, is quite conclusive as to the

non-existence of any such principle. Indeed abundance of evidence now

lies before the public, from various sources, in proof of the saying of

Fontenelle being fully applicable to the question of cholera--"When a

thing is accounted for in two ways, the truth is usually on the side

most opposed to _appearances_." How well mistaken opinions as to

contagion in cholera are illustrated in a pamphlet which has just

appeared from Dr. Zoubkoff of Moscow! This gentleman, it appears, has

been a firm believer in contagion, until the experience afforded him

during the prevalence of the disease in that city proved the contrary.

He tells us (p. 10), that in the hospital (Yakimanka) he saw "_to his

great astonishment_, that all the attendants, all the soldiers, handled

the sick, supported their heads while they vomited, placed them in the

bath, and buried the dead; always without precaution, and always without

being attacked by cholera." He saw that even the breath of cholera

patients was inhaled by others with impunity; he saw, that throughout

the district of which he had charge, the disease did not spread through

the crowded buildings, or in families where some had been attacked, and

that exposure to exciting causes _determined_ the attack in many

instances. He saw all this, gives the public the benefit of the copious

notes which he made of details as to persons, places, &c., and now

ridicules the idea of contagion in cholera. Grant to the advocates of

contagion in cholera but all the data they require, and they will

afterwards prove every disease which can be mentioned to be contagious.

Hundreds of people, we will say, for instance, come daily from a sickly

district to a healthy one, and yet no disease for some time appears; but

at last an "inexplicable condition of the air," and "not appreciable by

any of our senses" (admitted by Dr. Macmichael and others as liable to

occur, but _only in aid_ of contagion), take place; cases begin to

appear about a particular day, and nothing is now more easy than to make

out details of arrivals, there being a wide field for selection; and

even how individuals had spoken to persons subsequently attacked--had

stopped at their doors--had passed their houses, &c.[8] Causation is at

once connected with antecedence, at least for a time, by the people at

large, who see their government putting on cordons and quarantines,

and the most vague public rumour becomes an assumed fact. We even

find, as may be seen in the quotation given from Dr. Walker's report,

that contagionists are driven to the "somehow or other" mode of the

introduction of cholera by individuals; so that it may be deplored, with

respect to this disease, in the words of Bacon, that "men of learning

are too frequently led, from ignorance or credulity, to avail themselves

of mere rumours or whispers of experience as confirmation, and sometimes

as the very ground-work, of their philosophy, ascribing to them the same

authority as if they rested upon legitimate testimony. Like to a

government which should regulate its measures, not by official

information of its accredited ambassadors, but by the gossipings of

newsmongers in the streets. Such, in truth, is the manner in which the

interests of philosophy, as far as experience is concerned, have

hitherto been administered. Nothing is to be found which has been duly

investigated,--nothing which has been verified by a careful examination

of proof."

[Footnote 8: Since the above was written it has been very clearly shewn

how easily proofs of _this kind_ may be furnished to all disposed to

receive them. We perceive that a disease officially announced as _the

true_ cholera, has existed for nearly a month past at Sunderland, and

that among the thousands of people who left it within that time, nothing

could be more easy, had the disease appeared epidemically in other parts

of England, than to point out the _particular individual_ who had

"brought it" in some way or other; and this is the manner in which all

the fables about the propagation of cholera from one district to another

have gained credence. (Nov. 24th.)]

In their efforts to make out their case, there would seem to be no end

to the contradictions and inconsistencies into which the advocates

of contagion in cholera are led. At one moment we are required to

believe that the disease may be transmitted through the medium of an

unpurified letter, over seas and continents, to individuals residing

in countries widely differing in climate, while, in the next, we are

told--regarding the numberless instances of persons of all habits who

remain unattacked though in close contact with the diseased--that the

constitution of the atmosphere necessary for the germination of the

contagion is not present; and this, although we see the disease

attacking all indiscriminately, those who are not near the sick as

well as those who are at a very short distance, as on the opposite

side of a ravine, of a rivulet, of a barrack, or even of a road. They

assume that wherever the disease appears, _three_ causes must be in

operation--contagion--peculiar states of atmosphere (heat now clearly

proved not _essential_, as at one time believed)--and susceptibility

in the habit of the individual. However unphilosophical it is held to

be to multiply causes, the advocates of contagion are not likely to

reduce the number, as this would at once cramp them in their pleadings

before a court where sophistry is not always quickly detected. Those

who see irresistible motives for dismissing all idea of contagion,

look, on the contrary, for the production of cholera, to sources,

admitted from remote times to have a powerful influence on our

systems, though invisible--though not to be detected by the ingenuity

of man, and though proved to exist only by their effects.

Many who do not believe that cholera can be propagated by contagion

under ordinary circumstances, have still a strong impression that by

crowding patients together, as in hospitals or in a ship, the

disease may acquire contagious properties. Now we find that when the

_experimentum crucis_ of extensive experience is contrasted with the

feasibility of this, cholera, like ague, has not been rendered one bit

more contagious by crowding patients together than it has been shown to

be under other circumstances. We do not require to be told that placing

many persons together in ill-ventilated places, whether they labour

under ague, or catarrh, or rheumatism, or cholera, as well as where no

disease at all exists among them, as in the Calcutta black-hole affair,

and other instances, which might be quoted, _fever_, of a malignant

form, is likely to be the consequence, but assuredly not ague, or

catarrh, or rheumatism, or cholera. On this point we are furnished with

details by Dr. Zoubkoff, of Moscow, in addition to the many previously

on record. It may be here mentioned that, on a point which I have

already referred to, this gentleman says (p. 43), "I shall merely

observe that at Moscow, where the police are remarked for their

activity, they cannot yet ascertain who was the first individual

attacked with cholera. It was believed at one time that the disease

first showed itself on the 17th of September; afterwards the 15th was

fixed upon, and at last persons went so far back as August and July."

As this gentleman _had been_ a contagionist, occupied a very responsible

situation during the Moscow epidemic, and quotes time and place in

support of his assertions, I consider his memoir more worthy of

translation than fifty of your Keraudrens.

Respecting those mysterious visitations which from time to time

afflict mankind, it may be stated that we have a remarkable instance

in the "_dandy_" or "_dangy_" disease of the West India Islands,

which, of late years, has attracted the notice of the profession as

being quite a new malady, though nobody, as far as I am aware of, has

ever stated it to have been an imported one. We find also that within

the last three years a disease, quite novel in its characters, has

been very prevalent in the neighbourhood of Paris. It has proved fatal

in many instances, and the physicians, unable to assign it a place

under the head of previously-described disease, have been obliged

to invent the term "Acrodynia" for it. I am not aware that even

M. Pariset, the medical chief of quarantine in France, ever supposed

this disease to have been _imported_, and to this hour the cause of

its appearance remains in as much obscurity among the Savans of Paris,

as that of the epidemic cholera.

Considering all the evidence on the subject of cholera in India, in

Russia, Prussia, and Austria, one cannot help feeling greatly astonished

on perceiving that Dr. Macmichael (p. 31 of his pamphlet) insinuates

that the spreading of the disease in Europe has been owing to the views

of the subject taken by the medical men of India.

In turning now more particularly to the work, or rather compilation,

of Dr. Bisset Hawkins, let us see whether we cannot discover among what

he terms "marks of haste" in getting it up for "the curiosity of the

public" (_curiosity_, Dr. Hawkins!), some omissions of a very important

nature on the subject of a disease respecting which, we presume, he

wished to enlighten the public. And first, glancing back to cholera in

the Mauritius, Dr. Hawkins might, had he not been so pressed for time,

have referred to the appearance of cholera in 1829, at Grandport in that

island; when, as duly and officially ascertained, it could not be a

question of importation by any ship whatever. The facility with which he

supplies us with "facts,"--the _false facts_ reprobated by Bacon, and

said by Cullen to produce more mischief in our profession than false

theories--is quite surprising; he tells us, point blank (p. 31),

speaking of India, that "when cholera is once established in a marching

regiment, it continues its course in spite of change of position, food,

or other circumstances!" Never did a medical man make an assertion more

unpardonable, especially if he applies the term _marching regiment_ as

it is usually applied. Dr. Hawkins leads us to suppose that he has

examined the India reports on cholera. What then are we to think when we

find in that for Bengal the following most interesting and conclusive

statements ever placed on record? Respecting the Grand Army under the

Marquis of Hastings, consisting of 11,500 fighting men, and encamped in

November 1817 on the banks of the Sinde, the official report states that

the disease "as it were in an instant gained fresh vigour, and at once

burst forth with irresistible violence in every direction. Unsubjected

to the laws of contact, and proximity of situation, which had been

observed to mark and retard the course of other pestilences, it

surpassed the plague in the width of its range, and outstripped the most

fatal diseases hitherto known, in the destructive rapidity of its

progress. Previously to the 14th it had overspread every part of the

camp, sparing neither sex nor age, in the undistinguishing virulence of

its attacks."--"From the 14th to the 20th or 22d, the mortality had

become so general as to depress the stoutest spirits. The sick were

already so numerous, and still pouring in so quickly from every quarter,

that the medical men, although night and day at their posts, were no

longer able to administer to their necessities. The whole camp then put

on the appearance of a hospital. The noise and bustle almost inseparable

from the intercourse of large bodies of people had nearly subsided.

Nothing was to be seen but individuals anxiously hurrying from one

division of a camp to another, to inquire after the fate of their dead

or dying companions, and melancholy groups of natives bearing the

biers of their departed relatives to the river. At length even this

consolation was denied to them, for the mortality latterly became so

great that there was neither time nor hands to carry off the bodies,

which were then thrown into the neighbouring ravines, or hastily

committed to the earth on the spots on which they had expired." Let us

now inquire how this appalling mortality was arrested;--the report goes

on to inform us:--"It was clear that such a frightful state of things

could not last long, and that unless some immediate check were given to

the disorder, it must soon depopulate the camp. It was therefore wisely

determined by the Commander-in-chief _to move in search of a healthier

soil and of purer air_," which they found when they "crossed the clear

stream of the Bitwah, and upon its high and dry banks at Erich soon got

rid of the pestilence, and met with returning health." Now just fancy

epidemic cholera a disease transmissible by "susceptible articles," and

what an inexhaustible stock must this large army, with its thousands of

followers, have long carried about with them; but, instead of this, they

were soon in a condition to take the field. Against the above historical

fact men of ingenuity may advance what they please. There is no doubt

that, in the above instance, severe cases of cholera occurred _during

the move_, the poison taken into the system on the inauspicious spot,

not having produced its effects at once; it is needless to point out

what occurs in this respect in remittent and intermittent fevers. The

India reports furnish further evidence of mere removal producing health,

where cholera had previously existed. Mr. Bell, a gentleman who had

served in India, and who has lately written upon the disease,[9] informs

us (p. 84), that "removing a camp a few miles, has frequently put an

entire and immediate stop to the occurrence of new cases; and when the

disease prevailed destructively in a village, the natives often got rid

of it by deserting their houses for a time, though in doing so they

necessarily exposed themselves to many discomforts, which, _cæteris

paribus_, we should be inclined to consider exciting causes of an

infectious or contagious epidemic." We even find that troops have, as

it may be said, _out-marched_ the disease, or rather the cause of the

disease; that is, moved with rapidity over an extensive surface where

the atmosphere was impure, and thereby escaped--on the principle that

travellers are in the habit of passing as quickly as they can across the

pontine marshes. Mr. Bell says, "In July, 1819, I marched from Madras in

medical charge of a large party of young officers who had just arrived

in India, and who were on their way to join regiments in the interior of

the country. There was also a detachment of Sepoys, and the usual number

of attendants and camp-followers of such a party in India. The cholera

prevailed at Madras when we left it. Until the 5th day's march (fifty

miles from Madras) no cases of the disease occurred. On that day several

of the party were attacked on the line of march; and, during the next

three stages, we continued to have additional cases. Cholera prevailed

in the countries through which we were passing. In consultation with the

commanding officer of the detachment, it was determined that we should

_leave the disease behind us_; and as we were informed that the country

beyond the Ghauts was free from it, we marched, without a halt, until we

reached the high table land of Mysore. The consequence was, that we left

the disease at Vellore eighty-seven miles from Madras, and we had none

of it until we had marched seventy miles further (seven stages), when we

again found it at one of our appointed places of encampment; but our

camp was, in consequence, pushed on a few miles, and only one case, a

fatal one, occurred in the detachment; the man was attacked on the line

of march. We again left the disease, and were free from it during the

next 115 miles of travelling; we then had it during three stages, and

found many villages deserted. We once more left it, and reached our

journey's end, 260 miles further, without again meeting it. Thus, in a

journey of 560 miles, this detachment was exposed to, and left the

disease behind it, four different times; and on none of those occasions

did a single case occur beyond the tainted spots." What a lesson for

Dr. Hawkins! But _for whom_ could Dr. Hawkins have written his _curious_

book? Hear Mr. Bell in respect to the common error of the disease

following high roads and navigable rivers only:--"I have known the

disease to prevail for several weeks at a village in the Southern

Mahratta country, within a few miles of the principal station of the

district, and then leave that division of the country entirely; or,

perhaps, cases would occur at some distant point. In travelling on

circuit with the Judge of that district, I have found the disease

prevailing destructively in a small and secluded village, while no cases

were reported from any other part of the district." What is further

stated by Mr. Bell will tend to explain why so much delusion has existed

with regard to the progress of the disease being remarkably in the

direction of lines of commerce, or great intercourse:--"When travelling

on circuit, I have found the disease prevailing in a district _before

any report had been made of the fact, notwithstanding the most positive

orders on the subject_; and I am persuaded, that were any of the

instances adduced in support of the statement under consideration

strictly inquired into, it would be found that the usual apathy of the

natives of India had prevented their noticing the existence of the

disease until the fact was brought prominently forward by the presence

of Europeans. It should also be brought to mind, that cholera asphyxia

is not a new disease to these natives, but seems to be, in many places,

almost endemical, whilst it is well known that strangers, in such

circumstances, become more obnoxious to the disease than the inhabitants

of the country. Moreover, travellers have superadded to the remote cause

of the disease, fatigue and road discomforts, which are not trifling in

a country where there are neither inns nor carriages." (p. 89.) Cholera

only attacks a certain proportion of a population, and is it wonderful

that we should hear more of epidemic on high roads, where the population

is greatest? High roads too are often along the course of rivers; and

is there not some reason for believing, that there is often along the

course of rivers, whether navigable or not, certain conditions of the

atmosphere unfavourable to health? When Dr. Hawkins stated, as we find

at p. 131 he has done, that where the inhabitants of certain hilly

ranges in India escaped the disease, "these have been said to have

interdicted all intercourse with the people below," he should have

quoted some respectable authority, for otherwise, should we unhappily be

visited by this disease, the people of our plains may one day wage an

unjust war against the sturdy Highlanders or Welsh mountaineers.[10]

Little do the discussers of politics dream of the high interest of

this part of the cholera question, and little can they conceive the

unnecessary afflictions which the doctrine of the contagionists are

calculated to bring on the nation. Let no part of the public suppose for

a moment that this is a question concerning medical men more than it

does them; _all_ are _very_ deeply concerned, the heads of families more

especially so.

[Footnote 9: This is by far the best work yet published in England on

the cholera, but it is to be regretted that the author has not alluded

to the works of gentlemen who have a priority of claim to some of the

opinions he has published: I think that, in particular, Mr. Orton's

book, printed in India, should have been noticed.]

[Footnote 10: Something of this kind would have infallibly taken place,

had certain insane proposals lately made respecting the _shutting in_

of the people of Sunderland, been carried into effect.]

We see that the identity of the European and Indian epidemic cholera is

admitted on all sides; we have abundant proof that whatever can be said

as to the progress of the disease, its anomalies, &c., in the former

country, have been also noted respecting it in the latter; and Dr.

Hawkins, when he put forth his book, had most assuredly abundant

materials upon which to form a rational opinion. It is by no small

effort, therefore, that I can prevent all the respect due to him from

evaporating, when he declares, at page 165, that "the disease in India

was _probably_ communicable from person to person, and that in Europe it

has _undeniably_ proved so." But Dr. Hawkins is a Fellow of the College

of Physicians, and we must not press this point further than to wish

others to recollect that he has told us that he drew up his book in

haste; and, moreover, that he wished to gratify the _curiosity_ of the

public. The Riga story about the hemp and the fifteen labourers I shall

leave in good hands, the British Consul's at that city, who was required

to draw up, for his government, a statement of the progress, &c. of

the cholera there, of which the following is an extract:--

"The fact of non-contagion seems determined, as far as a question can

be so, which must rest solely upon negative evidence. The strongest

possible proof is, the circumstance, that not one of the persons

employed in removing the dead bodies (which is done without any

precaution) has been taken ill. _The statement of fifteen labourers

being attacked, while opening a pack of hemp, is a notorious falsehood._

Some physicians incline to the opinion, that the disease may sometimes

be caught by infection, where the habit of body of the individual is

predisposed to receive it; the majority of the faculty, however,

maintain a contrary doctrine, and the result of the hospital practice

is in their favour. There are 78 persons employed in the principal

hospital here; of these only two have been attacked, one of whom was an

'_Inspecteur de Salle_,' and not in immediate attendance upon the sick.

I am assured that the other hospitals offer the same results, but as I

cannot obtain equally authentic information respecting them, I confine

myself to this statement, on which you may rely. On the other hand, in

private families, several instances have occurred where the illness of

one individual has been followed by that of others: but, generally, only

where the first case has proved fatal, and the survivors have given way

to grief and alarm. Mercenary attendants have seldom been attacked,

and, as mental agitation is proved to be one of the principal agents

in propagating or generating the disease, these isolated cases are

attributed to that cause rather than infection.

"It is impossible to trace the origin of the disease to the barks;

indeed it had not manifested itself at the place whence they come till

after it had broken out here. The nearest point infected was Schowlen

(at a distance of 200 wersts), and it appeared simultaneously in three

different places at Riga, without touching the interjacent country. The

first cases were two stone-masons, working in the Petersburg suburbs, a

person in the citadel, and a lady resident in the town. None of these

persons had had the slightest communication with the crews of barks, or

other strangers, and the quarter inhabited by people of that description

was later attacked, though it has ultimately suffered most.

"None of the medical men entertain the slightest doubt of the action of

atmospheric influence--so many undeniable instances of the spontaneous

generation of the disease having occurred. Half the town has been

visited by diarrhoea, and the slightest deviation from the regimen now

prescribed (consisting principally in abstinence from acids, fruit,

beer, &c.) invariably produces an attack of that nature, and, generally,

cholera: fright, and intoxication, produce the same effect.

"Numerous instances could be produced of persons in perfect health, some

of whom had not left their rooms since the breaking out of the disease,

having been attacked by cholera, almost instantaneously after having

imprudently indulged in sour milk, cucumbers, &c. It is a curious

circumstance, bearing on this question, that several individuals coming

from Riga have died at Wenden, and other parts of Livonia, without a

single inhabitant catching the disease; on the other hand, it spreads in

Courland, and on the Prussian frontier, notwithstanding every effort to

check its progress. The intemperance of the Russians during the holidays

has swelled the number of fresh cases, the progressive diminution of

which had previously led us to look forward to a speedy termination of

the calamity." This is a pretty fair specimen of the _undeniable_ manner

in which cholera is proved to be contagious in Europe, and we shall, for

the present, leave Dr. Hawkins in possession of the full enjoyment of

such proofs.

Some attempt was made at Sunderland, to establish that, in the case

which I mentioned in my last as having proved fatal there, the disease

had been imported from foreign parts, but due inquiry having been made

by the collector of the customs, this proved to be unfounded; the man's

name was Robert Henry, a pilot:--he died _on the 14th of August_.[11]

[Footnote 11: In a former letter I alluded to cases of cholera which

appeared this year at Port Glasgow; I find that the highly interesting

details of those cases have been just published:--_they should be read

by everybody who takes the smallest interest in the important questions

connected with the cholera_. The London publishers are Whittaker and

Co.]

Abroad we find that, unhappily, the cholera has made its appearance at

Hamburgh; official information to this effect arrived from our Consul

at that place, on Tuesday the 11th inst. (October). The absurdity of

cordons and quarantines is becoming daily more evident. By accounts

from Vienna, dated the 26th September, the Imperial Aulic Council had

directed certain lines of cordon to be broken up, seeing, as is stated,

that they were inefficacious; and by accounts of the same date, the

Emperor had promised his people not to establish cordons between certain

states.

We find at the close of a pamphlet on cholera, lately published by Mr.

Searle, a gentleman who served in India, and who was in Warsaw during

the greater part of the epidemic which prevailed there this year, the

following statement:--"I have only to add, that after all I have heard,

either in India or in Poland, after all I have read, seen, or thought

upon the subject, I arrive at this conclusion, that the disease is not

contagious."

In confirmation of the opinion of Mr. Searle, we have now the evidence

of the medical commission sent by the French government to Poland.

Dr. Londe, President of that commission, arrived in Paris some days ago.

He announced to the minister in whose department the quarantine lies,

as well as to M. Hèly D'Oissel, President of the Superior Council of

Health, that it was proved in Poland, entirely to his satisfaction,

as well as to the satisfaction of his five colleagues, that the cholera

_is not a contagious disease_.

The Minister of War also sent _four_ medical men to Warsaw. Three of

them have already declared against contagion; so it may be presumed that

the day is not far distant when those true plagues of society, cordons

and quarantines against cholera, shall be abolished. Hear the opinion of

a medical Journalist in France,--after describing, a few days ago, the

quarantine and cordon regulations in force in that country:--"But what

effect is to be produced by these extraordinary measures, this immense

display of means, and all these obstructions to the intercourse of

communities, against a disease not contagious; a disease propagating

itself epidemically; and which nothing has hitherto been able to arrest?

To increase its ravages a hundred-fold,--to ruin the country, and to

make the people revolt against measures which draw down on them misery

and death at the same time." What honest man would not _now_ wish that

in this country the cholera question were placed _in Chancery_; where,

I have no doubt, it would be quickly disposed of. I shall merely add,

that the ten medical men sent from France to Poland, for the purpose

of studying the nature of cholera, have all remained unattacked by the

disease.

October 15, 1831.

Letters on the Cholera Morbus. Containing ample evidence that this disease, under whatever name known, cannot be transmitted from the persons of those labouring under it to other individuals, by contact—through the medium of inanimate substances—or through the medium of the atmosphere; and that all restrictions, by cordons and quarantine regulations, are, as far as regards this disease, not merely useless, but highly injurious to the community. · 第 13 / 34 题