CHEMISTRY OF METABOLISM

[Sidenote: Meaning of metabolism]

Metabolism is a word used to describe all processes that take place

within the body from the time food is absorbed from the digestive

organs until it is passed out of the body through some of the excretory

channels. To be more accurate, it means the sum of both the anabolic,

or constructive, and the catabolic, or destructive, processes that

continually go on in the animal body.

[Sidenote: Distinction between anabolism and catabolism]

The process of metabolism is chiefly one of tearing apart, or of

breaking down, complex chemical substances into simpler forms of matter.

Formerly, all processes in animal life were considered to be those

of tearing down, or of simplifying, chemical compounds; while plant

life was considered to be chiefly the process of building up complex

substances from simpler forms of matter. This distinction, however, is

rather general with many exceptions. The two terms, "anabolism" and

"catabolism" are sometimes used to distinguish between the processes of

building up complex chemical compounds, and the oxidizing or tearing

down of such compounds by effort or activity. Thus, the formation of

muscular tissue from the digested proteid materials would be a process

of anabolism, or construction, while the conversion of glucose in the

muscle-cells, into carbon dioxid and water would be an example of

catabolism, or destruction.

[Sidenote: Catabolism a process of oxidation]

The process of catabolism is, in general, one of oxidation; that

is, oxygen is added to the chemical compounds taken from the food

we eat, forming simpler substances which are excreted from the body

as waste-products. Oxidized carbon in the body forms carbon dioxid;

hydrogen is oxidized into the form of water, while nitrogen leaves the

body in the more complex and incompletely oxidized substance known

as urea, the chemical formula of which is COH₄N₂. A small portion of

nitrogen leaves the body in the form of uric acid, C₅H₄N₄O₃.

[Sidenote: Why muscular work produces warmth]

The process of anabolism usually absorbs energy or heat from the

surrounding material, while catabolism produces heat as a result of

oxidation, as do ordinary fuels. This explains why muscular work warms

the body.

We may study metabolism best by considering the two purposes food serves

in the animal body, as follows:

Encyclopedia of Diet: A Treatise on the Food Question, Vol. 1 · 第 115 / 143 题