HYDROPHOBIA.

This term has been erroneously applied to the disease arising from the

bite of a rabid animal, since many instances are recorded of mad dogs not

only drinking freely of water and other fluids, but actually swimming

across rivers; while, on the other hand, the horror of water has attended

maladies totally unconnected with rabid injuries: Sauvages plainly

expresses himself on this subject. "Apud Gallo-provincales, experientia,

canes lubosque rabidos bibisse, munducasse, flumen transnasse, ut olim

Maralogis et bis Forolivii observatum, adeoque nec potum aversari." Dr.

James relates the case of a mad dog that drank both milk and water, and

swam through a pond. Similar cases are recorded of mankind.

This disease was known to the ancients, and the Greek term for rabies was

_lyssa_, referred to several times by Homer, when Hector is compared to a

mad dog by Teucer and Ulysses. It was also known by the name of

_cynolisson_, _phobodipson_, and _hygrophobia_. According to Plutarch, the

disease was first observed in the time of Asclepiades. Coelius

Aurelianus is the most correct of the ancient writers on the subject. This

disease, although it may appear in every climate, is far less common in

hot regions than in those of a moderate temperature. In the West Indies it

is unknown; nor has it been observed in South America. In Egypt and Syria

it has never been seen. Mr. Barrow informs us that at the Cape of Good

Hope, and amongst the Caffres, their dogs are exempt from the malady,

although constantly fed upon putrid meat.

Water-dread has been observed in various rheumatic and inflammatory

affections, and frequently arises in a spontaneous manner; while many

cases are recorded of the alarming symptoms being witnessed when no rabid

bite has been inflicted. Violent passions, both in men and animals, seem

to impart a peculiar acrimony to the saliva. Meekren, Wolff, Zacutus

Lusitanus, mention fatal cases after the bite of a man in a passionate

fit. Le Cat gives a case of death produced by the bite of an enraged duck.

Thiermayer gives us two fatal cases of the bite of a hen and a goose, and

Camararius has an instance of epilepsy produced by the bite of a horse.

Of the cause of this disease we are utterly ignorant: thirst, without the

means of quenching it,--the use of putrid food,--sultry weather, have been

considered as producing the fearful disorder; but no one instance is

recorded that can justify the opinion. The streets of Lisbon are crowded

with dogs, feeding upon disgusting offal, under a burning sky, yet rabies

is scarcely ever observed among them. It is more probable that certain

mental emotions, such as anger and fear, have a peculiar influence on the

animal. All the aggregate symptoms of the disease show that the nervous

system is disturbed; and the singular effect of confidence in the

treatment of persons bitten by a rabid animal, confirms the fact. This is

further proved by many cases of hydrophobia unconnected with rabid bites.

Marcel Donat relates the case of a woman who complained of pains in the

neck and right arm, with constant trembling. In three days the pain

ceased, but the tremor continued; a sense of suffocation followed, which

was attended with a horror of water and every liquid, although the throat

was burning. In five days she died in excruciating agonies, but preserving

her senses until the last. Koehler saw a young soldier, who, having

fallen asleep against a stove, was suddenly awakened with a sensation of

intense thirst, which he quenched with a draught of cold water.

Hydrophobia immediately ensued, and the next day terminated his existence.

Selig relates the case of a man at Neukirchen, who was attacked with all

the alarming symptoms of this malady after having laboured in the fields

on a very hot day, and bathed in the river. The following day he was

affected with violent rheumatic pains, which shortly ushered in an

intolerance of fluids, and inability of swallowing. In the course of

twenty-four hours he expired. It appeared upon inquiry that a year before

he had purchased from the hangman of the town some dog's grease, to rub

himself to relieve some troublesome affection; and it was stated that the

dog had been killed by a gamekeeper, who suspected him of being mad.

Cases of plague have been attended with water-dread. Lalius Diversus saw a

woman labouring under the epidemic, who was thrown into agonies when she

even saw other persons drinking. Sarcotius, in his history of the epidemic

diseases of Naples, informs us that the fever was invariably attended with

hydrophobic symptoms. The fever that prevailed at Breslau in 1719,

presented the same peculiarity.

Various venene substances have also been known to give rise to this

disease. Professor Brera, of Pavia, witnessed it after the use of

stramonium. Rancid oils have caused similar accidents. In regard to the

causes that produced madness in dogs, numerous experiments have been made,

particularly in the Veterinary School of Alfort: one dog was fed with

salted meat, and totally restrained from drinking; another was allowed

nothing but water; and the third was not allowed food or drink of any

kind. The first died on the forty-first day; the second on the

thirty-third; and the third on the twenty-fifth; not one of them evincing

any symptoms of rabies.

It appears that a peculiar predisposition renders some individuals more

subject to the accidents that follow the bite of rabid animals than

others. Mr. Hunter gives an instance in which, out of twenty persons who

were bitten by the same dog, only one received the disease. It appears,

however, that this virus is less volatile than most others, and is capable

of remaining in a dormant state for a very long period; and if we are to

give credence to many reports on the subject, it may linger in the system

for several years. At other times, its destructive nature has proved

immediately injurious. Heisler has given a case where a man was affected

by merely putting into his mouth the cord by which the mad dog had been

confined. Palmarius relates the case of a peasant, who, in the last stage

of the disease, communicated it to his children by kissing them. It has,

however, been clearly demonstrated, that inoculation of rabid saliva does

not propagate the distemper. Experiments were made both by Magendie and

Breschet in 1813. In 1800, when a dresser in the Hotel Dieu of Paris, I

witnessed several experiments of the kind, and with similar results. At

the same period, I had occasion to observe the effect of imagination in

many cases. Several persons had been bitten by a rabid dog in the Faubourg

St. Antoine, and three of them had died in our wards; a report, however,

was prevalent that we kept a mixture that would effectually prevent these

accidents; no less than six applicants were served with a draught of

coloured water, and in no one instance did any accident ensue.

The period of the development of the accidents after the bite in animals

is various. According to Meynall, the disease appears amongst dogs from

ten days to eight months after the injury. In the hounds of Earl

Fitzwilliam, who were bitten in June 1791, the intervals varied from six

weeks to six months. Dr. James made a similar observation in Mr. Floyer's

pack.

No malady has been submitted to more curious and fearful modes of

treatment than hydrophobia; and in many cases such has been the dread of

the disease, that patients have been smothered or drowned. Dioscorides

seared the wound with irons heated to whiteness; other practitioners first

excised the wounded part, and then applied fire or caustic. While fire was

resorted to by some practitioners, water was recommended by others, and

submersion in a river or a pond has frequently been urged as an effectual

remedy. In the time of Celsus, the miserable sufferer was thrown without

any warning into a fishpond, alternately plunging his head under water and

raising it: when the poor wretch could swim, he was forcibly kept immersed

until filled with water. After this experiment, which Celsus terms the

_unicum remedium_, for fear that the patient might be attacked with

convulsions, he was taken out of the pond, and soused in warm oil. Van

Helmont recommended that the poor devil should be kept under water while

the psalm _Miserere_ was sung, and most probably the terrified choristers

were not expeditious in their performance. Morin relates the case of a

young woman, twenty years old, who was plunged in a tub of water, with a

bushel of salt dissolved in it, and dipped repeatedly, until she became

insensible; however, much to the surprise of the bystanders, who thought

her dead, she recovered, and could not only look upon water, but was able

to drink it. Bleeding nearly to death, mercury, cantharides, and various

medicines, have been also called into aid; but none have appeared to prove

effectual in curing this dreadful disorder. One of the most singular modes

of treatment was the introduction of rabid blood into the system of the

patient,--in fact, a homoeopathic plan of Dr. Rithmeister of Powlowsk,

in Finland, who has recorded several cases to prove that the blood of a

rabid animal, when drunk, is a specific against canine hydrophobia. The

doctor communicates a letter from Dr. Stockmann, a Russian physician,

stating this practice to be both common and effectual in White Russia.

With a view of producing a fresh poisonous action that might neutralize

the former one, it has also been proposed that a venomous serpent should

be made to inflict a wound under the bite of the mad dog. I do not believe

that this experiment has ever been tried; and, as Good observes, the claim

of ingenuity is, most probably, the only one it will ever have to receive.

This fatal disease is enveloped in so much darkness, both as regards its

causes and its treatment, that it may well be considered one of the

opprobriums of the profession. The experiments of my late friend Sir David

Barry are, however, of great importance; and in many cases of poisonous

wounds, the application of cupping-glasses has been followed by evident

favourable results.

To ascertain the existence of rabies in animals, more especially in dogs,

is a matter of great importance, as being frequently the source of moral

depression or of sanguine hope, that may tend to increase or diminish the

severity of the accidents. One may apprehend madness in a dog when we see

the animal dull, and seeking solitude and darkness, his sleep disturbed,

and when awakened refusing food or drink. Its head droops, the tail hangs

between the legs. The animal soon quits the abode of his master, the mouth

secreting a viscid foam, the tongue pendulous and dry, the eyes bright and

sparkling. His gait soon becomes uncertain; now precipitate, then slow and

undecided. Impatient, and parched with a burning thirst, he cannot rest;

and the sight of any fluid occasions an instinctive shudder. The rabid

symptoms now become more violent; the animal will attack and bite other

dogs, although much superior in strength. It is asserted that dogs avoid

him with terror. On these occasions the fury of the animal is not to be

controlled; all ties of attachment are dissolved; and his master is but

too frequently the first victim of his indiscriminate rage. Hence the

absurd popular notion that mad dogs inflict their first bite on those to

whom they are attached,--a circumstance that simply can be attributed to

the natural endeavours of a master to check the violence of a domestic

creature whom he generally can control. Mad dogs seldom bark, but express

their angry uneasiness with a growl, which gradually becomes weaker, until

the animal staggers, droops, and dies. Yet as there may exist many

maladies amongst animals in which these symptoms are observed, to destroy

them, as is usually the case, is a most absurd practice, since the

individuals whom they may have bitten will sink into a fatal despondency;

whereas, by allowing them to live, if they recover, it is evident that the

patient will be easily persuaded that the dog was not in a rabid state.

The following cases, recorded by Dr. Perceval, are curious instances of

the dormant state of this fearful virus, the effects of which are

accidentally developed.

A wine-porter was labouring under a low fever; after a time appeared some

symptoms of hydrophobia, and much inquiry elicited the recollection of his

having been slightly bitten by a dog six weeks before. In the interval he

was convicted of some fraudulent practice in the cellar of his master, to

whom he owed great obligation, and was dismissed with disgrace. Anxiety on

this event seemed to produce the fever, which terminated in rabies.

Lately an officer was bitten by a dog, whose madness being recognised, the

bitten part was excised immediately: after an undisturbed interval of two

months, he was advised to go to England to dissipate the recollection of

the accident. There he exercised himself violently in hewing wood, felt

pain in the hand which had been bitten, embarked for Ireland, had symptoms

of hydrophobia on board the packet, and died soon after his arrival. From

the varying period of attack, we might infer that the influence of

occasional causes is very considerable. In the last patient, hydrophobia

supervened exactly five weeks from the time of the bite: he lost one

hundred and twenty ounces of blood in twelve hours, which sunk him much;

violent perspiration, and at length delirium, attended the water-dread;

during the last twenty-four hours he swallowed, and recovered his senses;

and died slightly convulsed, whilst cutting an egg. These cases seem to

point out agitation of mind and feverish excitation as powerful occasional

causes.

Herman Strahl has recently related the following case of rabies in which

the dog that had bitten the patient was not mad. In the month of January,

1833, an innkeeper was taken ill. The doctor found him dressed, and

stretched upon his bed. He did not complain of any particular ailment, but

loathed all food. He at last admitted that he experienced some difficulty

in swallowing; and his mother having offered him a cup of tea, he refused

it with a sense of horror, and his countenance immediately assumed a

character of ferocity that terrified the bystanders. An apple having been

given to him, he ate it without repugnance. It was now discovered that,

five weeks before, he had been bitten by a dog he was training; and the

wound was slow in healing. The dog was sought, and did not show the

slightest sign of disease,--barking, playing, and drinking freely. In the

evening the patient's case was aggravated; and it was with the utmost

difficulty that he was made to swallow a spoonful of ptisan. The next day

he was seized with a violent attack of rabies: seeing one of his sisters

drinking, he fell into a furious rage, dashed a looking-glass to pieces,

and entreated his relatives to withdraw, as he otherwise would inevitably

bite them. This outrageous paroxysm lasted half an hour; at its expiration

he fell into a tranquil sleep. But at night he was seized with another

attack; and he began to howl and imitate the barking of a dog, and

commenced breaking every thing in the room of a shining appearance. His

sisters fled in dismay; but he seized his mother, a woman of sixty-five

years of age, cast her on the ground, and bit her in the cheek. After this

desperate act, he seemed to be struck with a conviction of what he had

done, and became more tranquil; but, half an hour after, on entering his

chamber, he was found dead, his head under the bedclothes. His mother did

not experience any accidents from the injury.

It is singular that, in this miserable condition, the patients will

frequently show singular partialities; and, although repulsing any fluid

offered to them by some individuals, will take it from others, and

attempt, however vainly, to drink. In the Hotel Dieu of Paris, a young

girl, affected with hydrophobia, would only take a cup of ptisan from me;

but with looks of inexpressible anxiety returned it to me, after having

struggled to moisten her burning lips. At Boulogne, a postilion, bitten by

a mad dog, was violent with every one but one of my nephews: from him he

also accepted drink, although unable to swallow it; before dying in

excruciating agonies, he repeatedly asked for him, and begged that he

might be sent for. He would not allow, even in his last moments, any other

person to come near him;--another striking instance of that unknown power

of sympathy to which I have frequently alluded in the preceding pages.

Curiosities of Medical Experience · 第 185 / 214 题