POISON OF THE UPAS, OR IPO.

Such are the names given by the natives of the Molucca Islands and in the

Indian Archipelago to a deadly poison which is used to impregnate the

heads of their arrows. The tree from which it is extracted is named _Bohou

Upas_, _Boa Upas_, and _Pohou Antiar_. Various accounts of its deleterious

nature have been given by ancient travellers. Cleyer and Spielman

described it upwards of a century back, and state that no antidote to its

dreadful action is known, though vomiting, produced by the most disgusting

means, was considered the only method of arresting its dire effects.

Spielman asserts that the land for several miles round these trees is

desolate and barren, for no plant can grow under their influence. The

poison, he states, flows in a milky form from the tree, and no one can

approach it at this period, as one drop of the fatal juice falling upon

the face or hands produces instant stiffness of every limb, followed by

rapid death; it is therefore obtained at the end of long bamboo canes,

armed with a pointed tube to receive it when plunged into the bark.

Rumphius confirms in a great measure the above statements, and describes

the tree, which he divides into male and female: he adds, that they only

grow in the island of Celebes, and that all around the dreaded spot is

desert and consumed. A more recent Dutch traveller, Foersech or Fooerch,

did not let so fertile a subject escape, and has cultivated most

industriously this dreary desert in the following account.

Sterility prevails for upwards of ten miles round this dreadful tree on

the part of the island of Java where it grows. When criminals are

sentenced to death, they are offered a free pardon if they consent to seek

a small boxful of this valuable yet terrific poison. They are first sent

to the dwelling of a priest who resides at a safe distance from the spot;

there they arrive, accompanied by their disconsolate and wailing families.

They remain with this holy man for a few days, during which he affords

them both spiritual comfort and good advice; the latter urging the

precaution not to set out until the wind blows in such a direction as to

waft from them the floating emanations. On their departure on this dreaded

expedition he gives them a small box of silver or tortoise-shell, covers

their head and face with a leathern hood with glass eyes, and protects

their hands with a thick pair of gloves of the same material. He then

accompanies them about two miles on their sad journey, and then he

describes the hellish spot where this treasure is to be found as minutely

as any one can describe what he has not seen; then, giving the poor

pilgrim his blessing, he departs on his return. This worthy man informed

our traveller that, during thirty years which he had held that enviable

situation, he had sent off no less than seven hundred criminals, of whom

only twenty-two returned: and he confirmed the statement by exhibiting a

list bearing their names and the offences for which they had been tried.

Mynheer Foersech further assures his gentle readers that he witnessed

several of these expeditions, and entreated the culprits to bring him some

branches of the tree; but two withered leaves were the only specimens he

could obtain from the solitary wretch who had the good fortune to escape,

and who described the tree as growing on the borders of a rivulet, being

of moderate height, and surrounded by a cluster of young ones. The ground

around them was of a brown sandy nature, and strewed with the remains of

human victims. He also clearly ascertained that no living creature can

exist within fifteen miles of the spot. The streams that flow near it

yield no fish, and the birds that fly over it fall to the ground; several

of the latter were occasionally brought to the priest,--whether he ate

them, or not, the Dutchman does not inform us. Amongst various offenders

doomed to death by this poison he relates the case of thirteen ladies,

who, for the crime of infidelity, were inoculated in the bosom with the

point of a kritz or Malayan dagger dipped in the upas; and in sixteen

minutes they had ceased to live. By recent experiments upon animals this

part of his narration may be credited; but, in regard to the other

account, we must apply to it the French saying, "_Il vaut mieux y croire

que d'y aller voir_." Indeed the whole of Foersech's account is justly

considered a fiction.

However, some French travellers thought otherwise; and Mr. Deschamps,

physician and naturalist attached to the expedition of Mr.

D'Entrecasteaux, when in Java, ascertained that this wonderful tree was

not uncommon in the forests of the country, nor was the approach to it in

the slightest degree apprehended. The juice procured by incisions in the

bark was called by the natives _upas_ or _oupas_, and was of so active a

nature that it caused immediate death when thrown into the circulation.

The Malays mixed it with various other ingredients more especially galanga

and garlic, when they employed it. The Javanese only impregnated their

arrows with it for the chase: a proof that they did not consider it as

affecting the system of the slain animal. Most probably Foersech's priest

was aware of this circumstance when he accepted from the privileged

malefactors the game killed by the tree they had sought.

This tree, according to Deschamps, is named in the country, _pohou

antiar_; it frequently rises to the height of thirty or forty feet. When

one of its branches is broken, or its bark incised, a milky juice exudes,

which becomes inspissated when in contact with the atmosphere. In

appearance this tree bears some resemblance to our elm. Mr. Deschamps

confirms the relation of Rumphius, who stated that the Dutch, in their

wars with the natives, were obliged to wear thick buff cuirasses to

protect them against their poisoned missiles, the wounds of which were

inevitably fatal.

Further information relative to the upas has been afforded by the

ingenious Mr. Leschenault, who, during his residence in Java, procured two

specimens of the poisonous substance obtained in Java, and of that brought

from the islands of Borneo and Macassar. In Borneo, the mountaineers of

the interior, who are called _Orang-Daias_, collect it, and keep its

preparation a profound secret. They carry it carefully wrapped up in

palm-leaves. Their hunting arrows have heads spear-pointed, and

impregnated with this substance; those that are prepared for war bear a

shark's tooth fixed in a brass socket, and merely attached to the shaft by

the gum resin of the ipo; the barbed point remaining rankling in the wound

it has inflicted, the gum dissolves, and speedily brings on death. Mr.

Leschenault tried these arrows on dogs and other animals, and they expired

shortly after in horrible convulsions.

But the latest account of this celebrated tree is given by Dr. Horsfield

who was in Java during its occupation by our troops. He informs us that

although the Dutch surgeon Foersech's account must have been a

fabrication, yet there did exist a tree called the _Anchar_ from the sap

of which the natives prepared a fatal poison. The tree belongs to the 21st

class of Linnaeus, the _Monaecia_. The male and female flowers are produced

on the same branch at no great distance from each other, the females being

in general above the males. The seed-vessel is an oblong drupe, covered

with the calyx; the seed an ovate nut with cells. The top of the stem

sends off a few stout branches, which spreading nearly horizontally with

several irregular curves, divide into smaller branches, and form a

hemispherical, not very regular crown. The stem is cylindrical,

perpendicular, and rises completely naked to the height of sixty or

seventy, and even eighty feet. Near the surface of the ground it spreads

obliquely like many of our large forest trees. The bark is whitish,

slightly bursting into longitudinal furrows. Near the ground this bark is,

in old trees, more than half an inch thick, and when wounded yields

copiously the milky juice from which the poison is prepared. This juice is

yellowish, frothy, and becomes brown when exposed to the air.

In making these researches Dr. Horsfield had some difficulty with the

native labourers, who feared a contagious eruption, but nothing more. The

Doctor further informs us that it is fatal to animals,--destroying dogs in

an hour, mice in ten minutes, monkeys in seven, and cats in fifteen, while

a buffalo subjected to the experiment was two hours and ten minutes dying.

The natives of Macassar also call this venomous production _ipo_. They

have two varieties of the tree, as in Java; the one called _upas antiar_,

and the other, much more violent and prompt in its action, _upas tieute_

In the preparation of the poison for use much mystery is observed by the

natives, and various ingredients are mixed up with it; but as they are

known to be harmless, such as onion and garlic juice, pepper, ginger,

galanga, they are most probably employed to deceive the curious who might

wish to ascertain the nature of this deadly composition.

Mr. Leschenault having brought home a small quantity of this poison, it

was tried by Messrs. Delile and Magendie in several experiments, when it

was found to act more or less violently, according to the age and size of

the individual, or the quantity of the upas. One grain and a half

inoculated in a young dog killed it in four minutes, only producing one

convulsive fit. In a dog weighing fourteen pounds, half a grain of upas

occasioned death at the expiration of one hour and fifty-seven minutes,

during which the animal experienced several violent convulsions. A few

drops of diluted upas, injected in the chest of a dog, weighing twenty

pounds, occasioned a lock-jaw, which destroyed him in a minute and a half.

Eight drops injected in the jugular vein of a horse produced immediate

tetanus and speedy death. For further information regarding these cruel

experiments we must refer to the experimenter's publication. It appears,

however, that the power of this venomous substance is so intense that time

does not weaken it; for the upas employed in these experiments had been

collected and kept for upwards of seven years, when its effects were as

prompt as when tried in a recent state. The natives of Java consider

sea-salt as the best antidote, but Mr. Delile found it quite inert:

various experiments induced him to think that in these cases death is

produced by asphyxia; and he considers the means employed to restore

suspended animation in persons supposed to have been drowned, as the most

likely to save the life of individuals who might be wounded with this

substance. The rapidity with which poisonous substances are absorbed in

the system is truly terrific, more especially in such as are of a narcotic

nature. The latter act by abolishing all nervous energies, but when

applied locally their effects are also local, as is shown by the following

experiments of Mueller:

"I held the nerve of a frog's leg which was separated from the body, in a

watery solution of opium for a short time, and that portion of the nerve

lost its irritability, i.e. its property of exciting twitchings of the leg

when it was irritated; but below the part that the poison had touched the

nerve still retained this function."

It is therefore evident that before narcotic poisons can exert a general

influence they must be carried into the circulation. Duprey and Brachet,

two French physiologists, have sought to prove that animals cannot be

destroyed by narcotic poisons, introduced in the stomach, if the _nervus

vagus_ has been divided on both sides; at least, that they do not die so

soon. However, Wernscheidt, in thirty experiments on mammalia, could not

perceive this difference, provided the animals were of the same size and

species.

Prussic acid exerts its influence so rapidly that it cannot be supposed to

have been thrown into the circulation. The spirituous solution of the

extract of nux vomica introduced in the mouth of a rabbit, produces

immediate death, whereas when applied to any nerve distant from the brain

it produces no general symptoms.

This rapid effect of prussic acid is supposed to arise from its great

volatility and powers of expansion, by which it is diffused more quickly

through the circulation than the blood. According to Schrader one drop of

this substance introduced in the bill of a bird killed it in four or five

minutes. Hydrocyanic acid gas mixed with atmospheric air has when inhaled

destroyed dogs, cats, rabbits, and various birds, in from two to ten

seconds. Magendie found that the introduction of one drop of the acid in

the jugular vein caused instantaneous death; a glass tube dipped in this

perilous substance applied to the tongue of a dog, produced a similar

effect, which was also the result when applied to the eye.

It is not generally known that tobacco and its preparations are deadly

poisons, one drop of oil of tobacco introduced in the mouth of a dog

produced violent convulsions with hurried breathing; a quarter of an hour

after, the unfortunate animal seemed to be recovered, when the

introduction of another drop killed it in two minutes. M'Cartney and

Orfila obtained similar results, though no such effects were produced when

it was applied to a nerve or the surface of the brain.

The French poet Santeuil died from having drank wine in a glass containing

some snuff. In all cases of death produced by this substance the lungs are

found dense and livid.

It is not only in the upas that the Indians seek the means of poisoning

their missiles. In America they employ the _Ticronas_ a juice extracted

from various plants, and the preparation of which, transmitted from one

generation to another is considered a valuable secret. La Condamine

asserts that its mere odour is sufficient to destroy the criminals doomed

to smell it, but Fontana has found by many experiments that this assertion

was made upon report, which travellers too frequently rely upon to save

themselves the trouble of investigation. Arrows saturated with this

poison, become more active after having been dipped in hot water.

The Indians of Guiana dip their arrows in the juice of the _Woorara_, and

the _Curara_, which also occasions rapid death and decomposition of the

lungs. Humboldt informs us that the _Curara_ is obtained from the bark of

a tree called _Vejuco_ de _Mavacure_; it is inspissated over a slow fire

and then mixed with a gum drawn from the _Kiracagnero_. The Abbe Salvador

Gilii tells us in his history of America, that he has seen the strongest

animals succumb instantly when thus wounded, but the poison does not

produce any effect on their meat.

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