Hæmorrhoids and prolapsus ani are peculiarly prevalent in the upper

class of society. That small portion of English people who dine in the

evening seem to furnish more cases of hæmorrhoids for operation than all

the rest of the population. And I am inclined to attribute the

circumstance to the habit of taking the greater part of the food towards

the close of the day, after a long fast; by which means congestion of

the liver, and obstruction to the return of blood from the bowels is

induced. Many of the patients with hæmorrhoids are ladies who are far

from luxurious in their habits, indeed many of them are abstemious; and

many of the male patients are the reverse of sedentary, as they spend a

great part of their time in hunting, and other field sports. Again, the

complaint cannot in my opinion be attributed to highly seasoned food, as

I think the working classes use more pepper than fashionable people. I

am inclined to believe that the habit of taking the chief meal of the

day at twelve or one o’clock, is the principal reason why bad cases of

hæmorrhoids are comparatively so rare in the working and middle classes,

many of whom live luxuriously, and are more sedentary in their habits

than the higher class of society.

Several of the patients operated on for hæmorrhoids were extremely

blanched, from the continued loss of blood arising from the disease; but

these patients underwent both the action of the chloroform and the

operation very well. The operation, it must be remembered, is not

attended with loss of blood.

_Fissure of the Anus._ I have notes of forty-four cases in which I have

exhibited chloroform in operations for the cure of this disease. Two of

them were performed by the late Mr. Copeland. The sphincter ani was

divided in the greater number of the operations. In addition to these

cases, there were some in which fissure existed, along with hæmorrhoids,

or fistula _in ano_. The patient was always placed on his side, in the

same position as in the operation for hæmorrhoids.

_Operations for Fistula in Ano._ The position of the patient in this

operation should be the same as in those for hæmorrhoids and fissure of

the anus, unless the patient is placed on the back, in the lithotomy

position, as I have seen in a few cases.

I have memoranda of 218 cases in which I have given chloroform in

operations for fistula _in ano_. In many of the cases the sinuses were

very numerous and extensive. It is necessary that the patient should be

quite insensible during this operation, to prevent the possibility of

his moving suddenly whilst the bistoury is being used.

_Operations on Ovarian Tumours._ I have notes of three cases in which I

gave chloroform during the removal of an ovarian cyst. The first of

these was in March 1850. Twenty-four pints of liquid were first

evacuated from the tumour. It consisted of four cysts united together,

two of which contained serous fluid of slightly different colour; the

third contained serum tinged with blood, and the fourth and smallest

cyst, a purulent fluid. An incision was made, twelve or fourteen inches

in length, extending from the pubes to midway between the umbilicus and

sternum. Some slender adhesions were removed at one spot. The tumour was

attached by a membranous pedicle, with the left iliac fossa, and the

fundus of the uterus. Needles were passed through the pedicle, and it

was tied in three or four portions, when the tumour was removed. After

the tumour was removed, the patient seemed to breathe entirely by the

ribs, the diaphragm remaining relaxed, and not contracting, whilst the

wound in the abdomen was being closed. Scarcely any blood was lost

during the operation. The patient died of peritonitis early on the

fourth day.

The next case occurred on August 27th, 1850, and is reported in the

_Medico-Chirurgical Transactions_ for 1851. Mr. Duffin was the operator,

and the patient made a favourable recovery.

The third operation was performed on the 31st of January, 1854. The

patient was a spinster, twenty-eight years of age, and the tumour had

not been tapped. It contained about two gallons of clear fluid, and was

removed through an opening in the median line above the umbilicus, about

seven inches in length. There was no depression when the patient awoke

after the operation. She died within three days.

I administered chloroform in two cases where it was intended to remove

an ovarian cyst. In one case the cyst was so adherent to the peritoneum

that it could not be removed; in the other case, there was no cyst, but

some serum in the peritoneal cavity, and a tumour growing from the

fundus of the uterus. This tumour was allowed to remain. Several medical

men, in addition to the operator, had diagnosed an ovarian tumour in

this case. These two patients recovered.

I exhibited chloroform in four operations in which an ovarian cyst was

opened, and the cut edges of it sewed to the wound in the abdominal

parietes. These four patients, I believe, all died. I am quite certain

as regards three of them.

On March 10th, 1852, I administered chloroform in St. Mary’s Hospital to

a woman, apparently about thirty-five, who had suffered from an ovarian

cyst about eighteen years. Mr. Isaac Baker Brown made an incision, about

six inches in length, into the peritoneal cavity, drew out a portion of

the cyst, tapped it, and removed several pints of clear serum. He then

cut away a piece of the anterior wall of the cyst, about as large as the

hand, and allowed the rest of the cyst to remain loose in the abdomen.

The wound in the parietes of the abdomen was stitched up. If I remember

rightly, the patient died, but I have no note of the result.

_Operations for Cancer of the Vagina._ I have notes of eighteen cases in

which I have given chloroform for operations of this kind by the knife,

which would have been extremely painful without the use of an

anæsthetic.

I exhibited this agent, in 1848, to a lady, whilst the late Mr. Aston

Key applied the actual cautery to malignant excrescence of the os uteri;

and I have administered it in several cases in which potassa and other

caustics have been applied to the os uteri. In operations on the vagina

or perineum, the woman should inhale chloroform whilst lying on her

back; and when insensible, should be drawn to the edge of the bed, or

the foot of the operating table, and have the knees held back and

separated.

_Operations for Rupture of the Perineum._ I have notes of fourteen

operations for this accident. Six of them were performed by Mr. I. B.

Brown, five by Mr. Fergusson, and the others by Mr. Paget, Dr. Protheroe

Smith, and Mr. Henry Lee. Mr. Fergusson has, in five cases, performed an

operation for prolapsus uteri, by paring the edges of the outlet of the

vagina, and stitching them together so as to diminish the orifice.

I have given chloroform in several operations for vesicovaginal fistula,

some of which were performed by Mr. Spencer Wells; and also for the

removal of warts and other growths from the labia pudendi, either by the

knife or caustics.

_Removal of the Testicle; Amputation of the Penis, etc._ I have

memoranda of twenty-seven cases in which I have administered chloroform

during the removal of a testicle, generally for malignant disease; and

six cases in which I have administered it for amputation of the penis,

always for malignant disease. There were six operations, also, in which

a part of the penis was removed for malignant disease; and eleven cases

in which warts were removed from the glans penis, generally with the

knife. In two cases in August 1854, Mr. Acton destroyed a number of

venereal warts on the glans penis and prepuce by a caustic composed of

potassa and lime. In all the operations on the testicle and penis, under

chloroform, the patients have been lying on the back.

_Operations for Phymosis._ I have memoranda of 76 operations for

phymosis, in which I have exhibited chloroform. The operations were

generally in the adult, although the complaint was, in most cases,

congenital. I have known two cases in which cancer of the penis was

produced by the patient’s suffering a congenital phymosis to remain to

about the age of fifty. The cancer commenced in the glans from the

irritation of the retained urine. One of the patients died of the

disease.

_Removal of enlarged Bursa._ I have notes of six cases in which the

bursa of the patella was dissected out by the surgeons of King’s College

Hospital for housemaid’s knee. The patients were charwomen and domestic

servants. In two cases a bursa was removed from the forefinger.

_Evulsion of the Nails._ I have notes of twenty-five cases in which I

have given chloroform for cutting down the nail of the great toe, and

tearing away the whole, or the two edges of it; and also of three cases

in which one or more finger nails were removed by a similar process.

This operation is one of the most painful of the minor operations of

surgery. It is better that the patient should be lying when it is done

under chloroform.

_Laryngotomy._ I administered chloroform to one or two infants in which

Mr. Henry Smith performed laryngotomy for croup. I also administered it,

on four occasions, to a patient of Mr. Partridge, a boy four years old,

who was believed to have a button in some part of the air-passages. The

larynx had been opened a few days previously to the first occasion in

which I gave chloroform, and I administered it on a sponge, held near to

the tube in the larynx. It was necessary to give the vapour gently at

first, just as if it was entering in the usual way. When it was given at

all strong, whilst the patient was still conscious, he showed exactly

the distress that a patient experiences when he says that the vapour

produces a choking feeling; which confirms my opinion that the feeling

referred to the throat, from the action of pungent vapours and gases, is

caused by their presence in the lungs. The chloroform was given to keep

the child quiet whilst Mr. Partridge searched for the supposed button in

the larynx and bronchi. When the child recovered from the chloroform,

before the operation was concluded, the explorations in its air-passages

embarrassed the breathing much more, and caused more apparent

threatening of suffocation, than they did when he was under the

influence of the vapour. This little boy remained for months in King’s

College Hospital; and at last the embarrassment in his breathing

subsided, the tube was removed from the larynx, and the wound allowed to

heal; and he left quite well, although the button, which was supposed to

have gone down his windpipe at the moment when his symptoms first

suddenly came on, was never found.

I have administered chloroform in a great variety of surgical

operations, in addition to those mentioned above, but as they required

only the usual management in the application of the vapour, I need not

allude to them, but shall, however, make a few remarks regarding dental

operations.

_Extraction of Teeth._ It is the custom in the medical journals and

medical societies, to object occasionally to the use of chloroform in

tooth-drawing, as if the operation were not sufficiently severe to

require it. I will say nothing of the wives and daughters of medical men

in connexion with this subject, but will only allude to the case of an

elderly lady, who had for thirty years been the private friend, as well

as the patient, of one of the Council of the College of Surgeons. After

she had had ten necrosed teeth extracted, and had awakened from the

effects of the chloroform, her friend and surgeon, who had been looking

on, discoursed eloquently on her case, explaining how the state of her

mouth was ruining her health; how impossible it would have been for her

to go through the operation without chloroform, and what a great

advantage it was.

Dr. Watson says in his Lectures:[148] “I am not at all sure that the

increased longevity of modern generations is not, in some degree,

attributable to the capability of chewing their food which the skill of

the dentist prolongs to persons far advanced in life.” I have seen at

least fifty cases in which the dentist has been able to exert his skill

in enabling his patient to masticate only by the aid of chloroform;

cases of feeble, aged, or debilitated persons, whose mouths contained

between twenty and thirty stumps of teeth or necrosed teeth; and who

were able to get rid of them all at two or three operations a few days

apart; but without the opportunity of being made insensible, would

undoubtedly have continued with the mouth in a tender and painful state.

It was in consequence of the relief afforded by nitrous oxide gas, in

pain caused by a tooth, that Sir Humphrey Davy suggested its application

in surgical operations; it was for the extraction of a tooth that Mr.

Horace Wells first carried out the suggestion of Davy; and it was in the

extraction of teeth that Dr. Morton first employed sulphuric ether as a

substitute for nitrous oxide gas. These circumstances seem to point to a

demand for anæsthetics in operations on the teeth; and when the great

frequency of these operations is considered, it is probable that more

pain may be prevented during their performance than in any other class

of operations.

I have notes of 867 cases in which I have administered chloroform during

the extraction of teeth, chiefly by dentists living in this

neighbourhood: amongst whom are Mr. Saunders, Mr. Cartwright, Mr. Samuel

Cartwright, Mr. Arnold Rogers, Mr. Thomas A. Rogers, Mr. Tomes, Mr.

Bigg, Mr. Crampten, Mr. F. W. Rogers, Mr. Alfred Canton, Mr. Woodhouse,

Mr. Lintott, Mr. Rahn, Mr. Vasey, Mr. Sercombe, Mr. Fletcher, and

several others; and there is one dentist in the City, Mr. West of Broad

Street, whom I have frequently assisted. The number of teeth, or stumps

of teeth, extracted in these 867 operations, has been about 3021. In

some cases in which several teeth have been removed, I have not been

sure of the exact number, but have put down about the number.

The number of teeth extracted at an operation has varied from one to

nineteen. The latter number was extracted by Mr. Canton on one occasion,

and on two or three occasions, Mr. Arnold Rogers and Mr. Samuel

Cartwright extracted seventeen at one sitting; but these gentlemen and

others, as well as myself, have thought it better, as a general rule, to

make more than one operation, when the number of teeth to be drawn

exceeded ten, in order that the mouth might not contain too many wounds

at one time, and that the loss of blood might not be very great. A great

number of the operations have been for the extraction of the four first

permanent molars, in children about thirteen, as these teeth are very

apt to decay at an early period.

I have on 181 occasions, of which I have memoranda, given chloroform for

the extraction of a single tooth. I exhibited it lately to a lady, aged

eighty-six, whilst Mr. Bigg extracted an abortive wisdom tooth, which

had recently come through the gum, and was giving pain. She awoke in

about two minutes after the operation, and was quite cheerful and well.

The patients have been seated in an easy chair in all the operations on

the teeth, except in a very few cases where a female patient was too ill

to sit up. In many cases, and always if there was any feeling of

faintness, the patient has been placed on a sofa, after the operation,

for twenty minutes or half an hour. I am not aware of any inconvenience

from the chloroform, in any of the cases of tooth-drawing, excepting

sickness and vomiting, which in a very few of the cases have been

troublesome for some time.

It is necessary in tooth-drawing to make the patient unconscious, and to

continue the chloroform a little while after unconsciousness is induced,

till the sensibility of the edge of the eyelid is very much diminished,

or almost altogether suspended, otherwise the patient will probably make

a resistance that will interfere with the operation, or scream out and

alarm his or her friends. I nearly always take about four minutes in the

inhalation. It is not desirable to take longer than five or six minutes,

as the patient would be slower than is desirable in recovering

completely from the effects of the vapour.

The patient is usually in the third degree of narcotism when the

operation is performed, and, in this degree, as was previously stated,

there is not unfrequently a contracted and rigid state of the muscles.

This state often affects the muscles of the jaws, and interferes with

the opening of the mouth, if it be closed. I generally tell the patient

to keep his mouth open whilst inhaling, and by that means it often

remains open when he is insensible. Not unfrequently, however, he closes

it on becoming insensible. One can generally open it by pressing on the

chin; but as the chin does not afford a very favourable hold, there are

a very few cases in which the mouth cannot be opened easily in this way,

at least not unless the effects of the chloroform are carried further

than is desirable for these operations. I therefore carry with me a

little instrument of two blades, made to open by means of a screw. The

ends of the blades are covered with leather, and, if introduced between

the teeth, at the corner of the mouth on the side opposite to that on

which the dentist is about to operate, the mouth can easily be

opened.[149] The power of the instrument is only such that I can

scarcely open it with one hand, when I hold the blades with the other.

It would not enable one to open the mouth of an adult if he were closing

it by voluntary power; but the spasm caused by chloroform is very much

less powerful than the action of the muscles when influenced by the

will. I never use the instrument for opening the mouth when the patient

is closing it voluntarily under the influence of a disordered

consciousness, but always wait till consciousness and volition are

entirely suspended. When the mouth is once opened, it can generally be

kept open with the fingers, and the instrument may be withdrawn.

The bleeding during tooth-drawing is never so free as to interfere with

the breathing; but when more than two or three teeth are extracted, and

especially if they be in the back part of the mouth, some of the blood

which escapes nearly always flows into the stomach; it flows down the

fauces and œsophagus usually without any act of deglutition; but the

evidence of its having gone into the stomach is obtained in those cases

where the patient vomits. In consequence of the blood flowing into the

stomach, vomiting cannot so generally be prevented by the precaution of

not taking a meal before the operation in tooth-drawing as in other

operations; but the sickness usually subsides as soon as the patient has

emptied his stomach.

The chloroform has occasionally to be repeated in tooth-drawing before

the operation is completed, especially in cases where several teeth

require to be extracted. When this is the case, I always reapply it as

soon as the patient begins to show signs of feeling the operation,

without waiting till he recovers his consciousness. In many cases,

however, a number of teeth are extracted without any repetition of the

chloroform; and in the instances in which as many as fifteen, seventeen,

or nineteen teeth were extracted at one operation, it was chiefly

because the first application of the vapour enabled the dentist to take

out such a number, otherwise, in most of these cases, a number of the

teeth would have been left for a succeeding operation. It has

occasionally happened, however, that the chloroform has required to be

repeated, once or twice even, for the extraction of a single stump. When

the chloroform is repeated once or twice, it is generally a longer time

before the patient is able to leave the dentist’s house. I always

request the patients who are operated on at the dentist’s, to drive

home, as it is not advisable to walk, or use any exertion for an hour or

two after the action of chloroform. Indeed, the patient is usually

disinclined for any exertion for twenty minutes or half an hour after

the influence of this agent, and sometimes for much longer; although I

have seen a patient mount the box of a sort of dog-cart, and drive

himself away, within five minutes after having several teeth extracted

whilst he was in a state of complete insensibility from chloroform.

I have administered chloroform in a great number of cases for the

destruction of the nerves of the teeth. The patient requires to be made

as insensible in this operation as in tooth-drawing.

_Secondary Hæmorrhage_ after Operations. The hæmorrhage which

occasionally comes on several days after an operation, from sloughing,

ulceration, or the non-formation of a coagulum in an artery, is probably

as liable to occur now as formerly; but I believe that hæmorrhage, a few

hours after an operation, is much less frequent since the practice of

narcotism by inhalation. Before this practice, it was extremely common

for the patient to faint during an operation, when the bleeding of the

smaller arteries stopped, and they escaped the ligature, to break out in

hæmorrhage occasionally afterwards; but under the influence of narcotic

vapours it is unusual for the patient to faint, and consequently every

vessel which is capable of bleeding is tied during the operation.

CHLOROFORM IN PARTURITION.

When the practice of inhalation in midwifery was first introduced by Dr.

Simpson, he very naturally adopted the plan which is usually followed in

surgical operations, making the patient unconscious at once, and keeping

her so to the end of the labour. It was soon found, however, by other

practitioners, that this is not necessary; and, indeed, it would not be

safe in protracted cases. Drs. Murphy and Rigby were, I believe, amongst

the first to state, that relief from pain may often be afforded in

obstetric cases, without removing the consciousness of the patient; and

I soon observed the same circumstance.[150] Some persons, indeed, have

alleged that the pain of labour can always be prevented, without making

the patient unconscious of surrounding objects; whilst others have

asserted that no relief can be afforded unless unconsciousness be

induced. But both these opinions are directly opposed to experience.

There are comparatively few cases in which the suffering can be

prevented throughout the labour without interfering with consciousness,

although there are very many cases in which it can be in this way

prevented in the early part of the labour. This difference depends, in

some measure, on the constitution of the patient, but chiefly on the

severity of the pain to be prevented. It is in accordance with what is

observed in medical and surgical cases, that the pain should be removed,

in some instances, without abolishing consciousness, and that in other

instances it should not; for, in certain cases of neuralgia, the pain is

so severe, that no material relief can be obtained by chloroform as long

as consciousness is retained; and in surgical operations, although it

now and then happens that the minor and concluding parts of an

operation, such as tying vessels and introducing sutures, can be

performed without pain, whilst the patient is consciously looking on, a

free incision in the skin can hardly ever be made, under similar

circumstances, without pain.

With regard to the cases of labour in which chloroform may be employed,

it will be readily conceded that, in cases where the pain is not greater

than the patient is willing to bear cheerfully, there is no occasion to

use chloroform; but when the patient is anxious to be spared the pain, I

can see no valid objection to the use of this agent, even in the most

favourable cases. The benefits arising from chloroform in severe cases

of labour are experienced in a lesser degree in favourable cases; and

the patient may be fairly allowed to have a voice in this, as in other

matters of detail which do not involve the chief results of the case.

The determination of the kind of labours in which chloroform should be

used, or withheld, is really a matter of not much importance, because,

as we pass from cases that are severe and protracted to those which are

short and easy, the quantity of chloroform that is used, and the amount

of diminution of the common sensibility, and of interference with the

mental functions, become so trifling, that very little remains about

which to hold a discussion. Indeed, from what I have observed of the

continued use of this agent in medical cases, and its use by healthy

persons for experiment, I believe that the quantity which is inhaled in

a short and easy labour might be continued daily for an indefinite

period, without appreciable effect on the health.

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