On October 10, 1516, when he was resident at the Manor House of Cloux
near Amboise in Touraine with Francesco Melzi, his friend and
assistant, he showed three of his pictures to the Cardinal of Aragon,
but his right hand was now paralysed, and he could "no longer colour
with that sweetness with which he was wont, although still able to
make drawings and to teach others."
It was no doubt in these closing years of his life that he drew the
"Portrait of Himself" in red chalk, now at Turin, which is probably
the only authentic portrait of him in existence.