=Septic Nephritis; Pyelitis; Pyelonephritis; Surgical Kidney.=--Septic

infection of the kidney is usually the result of a process ascending

from the lower urinary passages, particularly when these are obstructed

by calculus, tumor, prostatic enlargement, or ureteral stricture. It

may follow catheterism either once or prolonged, especially when done

without strict precaution; or the infection may come from the other

direction _via_ the blood stream, as in typhoid and various other

fevers, the exanthems, and diphtheria. Gonorrhea is a frequent cause,

acting insidiously and by a creeping invasion, with the intervention of

a rather more abrupt cystitis. Nevertheless when gonorrhea is followed

by pyemia and metastatic abscess these form early in both kidneys, and

disaster quickly follows. These types of infection spreading upward

along the ureters do not spare the pelvis of the kidney, but expend

their first violence there. Beyond this they may extend to the renal

tissue proper, where they set up a true nephritis, which may prove

fatal.

=Symptoms.=--Clinical symptoms do not vary greatly except in detail.

They include fever, chills, and similar expressions of toxemia, with

more or less pain in the kidney, down the ureter, and even referred to

the ultimate distribution of the nerves sympathetically or anatomically

involved, _e. g._, to the testicle on the same side, often with

retraction of the scrotum, and down the thigh. There is a tendency to

_thamuria_ (frequency of urination) when the bladder is involved, as it

always is sooner or later. Pus and mucus are recognizable in the urine

by the naked eye, while a microscopic study of this fluid will reveal,

from the character of the cells, the extent and type of the invasion.

The tuberculous type will be considered separately. Suffice it to say

that in this form, however pure may have been its original type, it

becomes sooner or later converted into a mixed septic infection, with

which renal abscess is often connected. The gonorrheal type is nowise

clinically distinct, so far as the kidneys are concerned, but is to be

recognized either by the microscope or by other clinical evidence.

=Treatment.=--Such cases as the above may even perplex the surgeon,

since they complicate many other surgical conditions. Yet if they go no

farther than above described they are to be treated rather by internal

methods, _i. e._, diluents, with hot-air baths, and especially by

urotropin, the remedy of greatest value, while such drugs as aspirin,

benzosol, sodium benzoate and the like, in moderate doses and at rather

short intervals, may be administered to great advantage.

=Renal Abscess; Surgical Kidney.=--The conditions above described do

not necessarily nor often terminate with resolution. Not infrequently

suppuration follows, with resultant abscesses, which may be solitary

and possibly large, but are more likely to appear in multiple and

perhaps punctate form. Should this condition occur in one kidney alone,

it determines probably its ultimate destruction; if in both kidneys,

the prognosis is very grave, since later, if not immediately, such a

case will succumb to renal failure, due to the extra load put upon the

portion still capable of secreting. It is to kidneys thus crippled

by acute or subacute infections, with punctate abscess and similar

lesions, that in the past the term “_surgical kidney_” was applied,

because such kidneys were seen oftener in surgical than in so-called

medical cases.

Brewer has recently called attention to a type of _acute hematogenous

renal infection_, to which he has given an identity of its own.

The possibility of renal infection through the blood has been long

recognized, but it has been generally supposed to produce bilateral

lesions. Of late, however, it has been shown that these may be

unilateral, on account of the diminished resistance of one kidney

as the result of previous disease or injury, among the former being

calculus, renal retention, and floating kidney. While the colon bacilli

are most frequently at fault the infection is often of the pyogenic

or mixed type. It seems to be more frequent in women than in men.

The symptoms are those of an acute infection, often ushered in by a

chill, with sudden rise of temperature, sometimes followed by such

marked remission as possibly to suggest malaria. The pulse ranges

high. Abdominal pain is an almost constant symptom, although it is

usually vague and often shifting or referred. Sometimes it will cause

such a complaint as to lead to mistaken diagnosis in favor of an acute

appendicitis. Occasionally it radiates along the course of the ureter.

Tenderness in the costovertebral angle is nearly always present.

Muscle rigidity is frequent but inconstant. There is nearly always a

leukocytosis, with a percentage of about eighty polynuclears. Frequency

of urination may accompany these cases, but they will ordinarily be

diagnosticated by physical and urinary examination. The urine will

usually contain albumin, perhaps with pus, and occasionally a few

red blood cells. Urine obtained from the affected kidney by ureteral

catheterization will contain more of these evidences of abscess than

that from the other side. Brewer has had far better success in entirely

removing the affected kidney than in exposing and simply draining it.

He has thus done a great service in demonstrating the possibility of

unilateral acute and suppurative disease of the kidney, where diagnosis

is most obscure and the clinical picture one of acute general abscess

rather than of local affection, showing as well that the more acute

cases tend rapidly to terminate fatally unless promptly arrested by

complete removal of the affected organ.

As we consider the above infections, with others yet to be mentioned,

it becomes more necessary to appreciate those constituents and

characteristics of the urine which have for the surgeon the greatest

significance, and those methods of investigation which furnish him the

promptest and most satisfactory results.

The following include methods in present use for determining renal

_capacity and function_, _i. e._, the matters of greatest importance:

1. Catheterization of the ureters;

2. Cryoscopy of the blood and the urine;

3. Phloridzin test;

4. Chromocystoscopy;

5. The toxin test;

6. The test for electroconductivity (Kakells).

1. By _cystoscopy_, with _ureteral catheterization_, we determine

whether urine is secreted by both kidneys or but one, while the

secretion of each kidney may be separately collected and studied. Even

this method leaves much to be desired. Though one kidney be actively

diseased it may still contain sufficient tissue to make it partly

competent for its purpose, and undesirable to remove; or an organ with

very defective structure may, nevertheless, yield a certain amount of

nearly normal urine. These, then, are aids to determine the _character

of the morbid process_, and the information they furnish is valuable,

but not always sufficient.

2. _Cryoscopy_, based upon the physiochemical law that the freezing

point of the solution is proportionate to the number of molecules it

contains, _i. e._, to its molecular concentration, has revealed that

the blood of a person with severe kidney lesion freezes at a lower

temperature, while the freezing point of his urine would be much higher

than in a normal individual, because those materials which should have

been excreted in the urine are, on account of impaired renal function,

retained in the blood and do not get into the urine. The freezing point

of normal urine varies from -0.09° to -2.3° C.; the freezing point of

normal blood from -0.55° to -0.57° C. The reasoning employed in the

method is sound, but the method itself difficult, requiring special

apparatus and experience. Moreover, the limits of the possibility of

error are such that this method alone should never be relied on. It is

essentially a test of the _ability of the kidneys to act as filters,

but does not test their serviceability as secretory organs_.

3. The _phloridzin test_ is one of the most trustworthy for

estimating the secretory function of the kidneys, as it shows how

much active working epithelium remains in the organ. It consists in

the subcutaneous injection of 0.005 Cc. sterilized phloridzin with an

equal quantity of sodium benzoate, to hold the former in solution.

The bladder must be emptied just before the injection is given.

About an hour after its administration _sugar should appear in the

urine, if the kidneys are acting normally_. If they are to be studied

separately, catheterization of the ureters is necessary. The test is,

of course, worthless in diabetic subjects. It depends upon the amount

of sugar excreted, the time of its appearance, and the duration of its

elimination. If no sugar be present the kidneys are seriously affected;

if it be delayed, renal insufficiency is present. The average quantity

of sugar eliminated during the first half-hour, when the kidneys

are normal, is about 0.5 per cent. If the kidneys be diseased, this

quantity is reduced by a half, and there is very little more secreted

in the first than during the second half-hour. This valuable method is

unfortunately difficult of application and requires minutely careful

chemical tests.

4. _Chromocystoscopy_, introduced by Voelcker and Joseph, is perhaps

the simplest of all methods of estimating renal capacity. 20 Cc. of

a 0.4 per cent. solution of _indigo-carmine_ is injected into the

gluteal muscles. In fifteen or twenty minutes, if the kidneys be

normal, the cystoscope will reveal dark-blue urine flowing from the

ureteral orifices toward the median line, with a peculiar jet at

regular intervals of about twenty-five seconds, and lasting for perhaps

five seconds. There is both rhythm and force about this ejaculation.

If the color be pale, the jet weak, or the rhythm irregular, the

intervals prolonged or late, or if no flow whatever occur, there must

be hindrance in the secreting and filtering structure of the kidney, or

occlusion of the ureter. The results given by indigo-carmine in these

cases are superior to those furnished by methylene blue, since it is

not so much a solution as a mixture which is formed and ejaculated

as such. Moreover, in passing through the body the indigo-carmine

undergoes no reduction. By this method there is no necessity for

catheterization of the ureter. One needs only to use the cystoscope

with reasonable dexterity, and there is no necessity for chemical tests

of separate specimens. The method is generally useful in cases where

ureteral catheterization is made impossible by growths. It affords an

easy means of differentiation, for instance, between ovarian cyst and

hydronephrosis.

5. The _toxin test_ is one only to be carried out by the use of

animals, since it depends upon the amount of filtered urine required

to kill an animal after injection into its veins, the number of cubic

centimeters necessary to kill, divided by the weight of the animal,

being called the urotoxic co-efficient. It has greater laboratory than

clinical interest.

6. _Electroconductivity of urine_ is of value in determining the

capacity of the kidney for eliminating inorganic cells. It depends on

the resistance offered by the urine to the electric current. It is

complicated in method, requires special apparatus, and its results are

still of questionable value.

For _ordinary purposes_ the most trustworthy data for the surgeon who

is not provided with ample laboratory facilities are afforded by an

estimate of the _amount passed in twenty-four hours_, its _specific

gravity_, its _color and acidity_, and by the _presence or absence

of albumin_. The test-tube and the microscope then still afford

satisfactory means of deciding those matters which the surgeon needs to

know. If applied to urine collected separately from each kidney, they

may be regarded as trustworthy. If catheterization be impossible, then

it is advisable to inspect the ureteral orifices while elimination of

indigo-carmine is taking place.

=Hematuria.=--The significance of blood in the urine is rather that

of a _symptom_ than of a disease, although it should be admitted that

there are occasional patients who lose blood in this way, more or

less frequently, even periodically, without seeming to suffer in the

least. Hematuria may also be present as an expression of vicarious

menstruation. Again, blood may thus appear in scurvy and similar

conditions, especially in tropical climates; in certain of the

domestic animals its presence may be due to infection of the kidneys

by macroscopic parasites (the so-called “_black-water fever_” of men

and horses). Such cases as these are outside the pale of surgery.

Nevertheless general experience has shown that many cases of hematuria,

without perceptible changes in the kidney, have been benefited or

cured by exploratory nephrotomy. Among the causes ascribed for these

so-called “_essential hematurias_” have been incipient tuberculosis,

renal retention from prostatic enlargement, congestion from venous

obstruction (due to tight lacing or displacement from any cause), and

even the congestion of chronic nephritis.

=Treatment.=--When known or recognizable causes are absent, and the

ordinary therapeutic agents, the special styptics (cotarnin), and such

measures as hypodermoclysis with a 2 per cent. gelatin solution (see

Control of Hemorrhage) have failed, an exploration may be advised.

It is of the greatest advantage to be certain that but one kidney is

involved, or it may be necessary later to operate on the second kidney.

=Operative Treatment of Chronic Nephritis.=--The various changes

included under this head are usually bilateral. The term implies

a non-pyogenic infection of the renal bloodvessels, interstitial

tissues, and glomeruli or tubules, which produce changes, often spoken

of in this country as constituting _interstitial parenchymatous_ or

_diffuse_ forms of _nephritis_, and inducing gross changes which cause

the kidney to be spoken of as contracted, large, white, waxy, etc.

Discussion of the pathology of these conditions here is out of place.

They have all been grouped, most loosely, in common parlance as forms

of “_Bright’s disease_.” Apart from the significance of albuminuria and

the many terms implying peculiar features, the apparent hopelessness

of many of these conditions, and the disappointment following internal

treatment, finally led surgeons to attempt to ascertain what they could

accomplish. It was in 1886 that Péan operated on a case of chronic

nephritis with nephralgia and removed the kidney. Ten years later

Harrison made three nephrotomies, and, though under a wrong diagnosis

in each case, it was noticed that the symptoms all cleared up and that

albumin disappeared from the urine. About the same time Newman showed

that albumin and casts have often appeared in movable kidney, because

of torsion of the vessels, and that they disappeared after nephropexy.

Then Pousson, in 1899, reported some twenty-five cases of hematuria and

nephralgic nephritis, operated upon by nephrotomy and nephropexy, with

great benefit. In 1899, Israel was, perhaps, the first to formulate

rules for nephrotomy for these conditions. In 1899, also, Ferguson

claimed that chronic nephritis should be treated as are inflammations

elsewhere, by relief of tension and even drainage. Meantime, Edebohls

had been doing partial decapsulation and fixation in cases of so-called

unilateral nephritis (the possibility of which is disputed by the best

authorities, like Kümmel), and later extended his method to complete

decapsulation (_capsulectomy_), with replacement of the kidney in its

fatty bed, claiming that by and through the new adhesions thus produced

new and more complete as well as additional blood supply was furnished,

and that regeneration of the slightly altered parenchymatous tissue, as

well as absorption of exudates, was produced. (Guiteras.) The fact that

it seems now well established that these forms of chronic nephritis are

always bilateral does not of itself affect the cogency of Edebohls’

reasoning, if it be otherwise correct.

Accurate diagnosis has much to do with this problem. Israel has shown

that chronic nephritis is even more difficult of recognition in the

living than in the dead, not only after ordinary examination of the

capsule, but also after opening into the kidney. Age is not a serious

contra-indication, and enlargement of the heart is said frequently

to subside after these operations. If cardiac compensation be good

operation is permissible, if not otherwise contra-indicated. Edebohls’

method is to anchor the kidney to the muscles of the back, whether it

was previously movable or not. Primary healing is desirable, since

“nephritics” do not bear suppuration well.

=Indications for Operation.=--At present a satisfactory summary is

impossible. It is of the first importance that operation should be

undertaken _early_, since to wait until anasarca or other grave

conditions supervene is to invite disappointment as the result of a

procedure which is by many considered capital. The coincidence of

pronounced disease of any other type would be a contra-indication.

Bacteriuria, pyuria, etc., would perhaps make it more desirable

rather than otherwise. Cases of operative toxemia (postscarlatinal,

typhoid) and of cirrhotic type, without other contra-indications, are

the most favorable. When a careful examination of the patient and the

urine leads the surgeon to think that preparatory treatment may be of

advantage, he should find therein almost his only excuse for delay, if

operation is to be done. Low hemoglobin percentage should also lead to

postponement.

_Operation_ may consist of _nephrolysis_, or breaking down of

adhesions, by which pain is frequently relieved, of _decapsulation_, of

_nephrotomy_, and, finally, of _nephrectomy_, in case serious lesions

are disclosed. It is doubtful if benefit is due so much to formation

of new vessels as to a freer circulation of blood within the kidneys,

with their consequent improved opportunity for repair and elimination.

Guiteras, for instance, does not believe in total decapsulation, but in

partial exposure of a sufficient area on the posterior kidney surface

to assist in its fixation, if movable. Otherwise he considers that

simple division of the capsule over the convexity will be sufficient.

In cases of unilateral nephralgia and hematuria he advises nephrotomy,

not so much as an approved therapeutic measure as for exposure, perhaps

for revealing the possible existence of deep lesions.

[Illustration: FIG. 633

Acute pyelonephritis with multiple miliary abscess formation. (Israel.)]

The recent reports from various surgeons concerning the value of renal

decapsulation alone are by no means unanimously favorable, although a

majority of writers are in favor of exposure of the kidney, capsulotomy

and fixation, either by suture or tampon. Still, it does not seem at

present justifiable to maintain that decapsulation can be expected to

cure diffuse or deep-seated arteriosclerosis or degenerative processes

within the kidneys.

The question of the _suitable anesthetic_ is here one of importance.

For reasons set forth earlier in this work, ether should always be

avoided. If the operation be one that can be speedily performed,

nitrous oxide gas alone may suffice. Otherwise it should be done under

chloroform, preceded perhaps with ethyl chloride, or under somnoform.

=Pyonephrosis.=--As a condition this is to be distinguished from

ordinary abscess of the kidney, in that it implies the retention in

the renal cavity or pelvis of pus with eventual destruction of kidney

tissue. In other words it is an _empyema_ rather than an abscess. It

results from septic or tuberculous invasion, plus ureteral obstruction,

regardless of the obstructing cause, _e. g._, calculus, plugs of mucus,

stricture, kinking of ureter, or extrinsic tumor causing pressure.

Occlusion may be so complete that no urine escapes from the affected

kidney, while that from the other is clear, or the phenomenon may be

intermittent. There results more or less enlargement and often great

dilatation of the diseased kidney. Pus thus retained has been known to

be discharged into the intestine or even into the lung. Spontaneous

recovery is rare. Aspiration from the back in these cases is proper for

diagnostic purposes.

=Treatment.=--Pyonephrosis, like any other collection of pus, calls

for _incision_ (nephrotomy) and _drainage_, with removal of any

possible foreign body, such as calculus. If the entire kidney be found

destroyed, or so compromised as to jeopard its future, a _nephrectomy_

may be done at once, while it may be a secondary measure in cases of

permanent urinary fistula following drainage. So, too, if the kidney be

found tuberculous, it is better to remove it than to temporize.

=Perinephritis.=--To pus formed in a perirenal phlegmon is given the

term _perinephritic abscess_; this is sometimes due to external or

penetrating injuries; sometimes it appears as a primary condition

difficult of explanation; but it usually follows inflammation of

adjacent structures, such as the kidney itself (tuberculous pyelitis),

the liver, the colon, and the appendix. While perinephritis usually

terminates by suppuration, spontaneous recovery, with more or less

absorption of exudate, is known to occur. These perinephritic

collections sometimes attain enormous size, and are then sure to

migrate, always along lines of least resistance, which takes them

usually downward, either toward the loin or the groin. I once tapped

below Poupart’s ligament a collection which exceeded a gallon. These

abscesses may also, more rarely, burst into any of the adjoining

cavities, and discharge either by the mouth, bowel, or bladder, or even

externally.

=Symptoms.=--In addition to the usual systemic indications of the

presence of pus there may be _tumor in the lumbar region_, sometimes

with distinct fluctuation, usually with rigidity of the lumbar and

psoas muscles, perhaps even contractions of the thigh muscles which

may simulate hip disease. These abscesses have been mistaken for

peri-appendical phlegmons. If necessary to establish the presence of

pus the exploring syringe may be used, but this is rarely necessary.

=Treatment.=--While in the early stages the local application of

guaiacol may be of use, every collection of pus thus formed here, as

well as elsewhere, needs _evacuation and drainage_. This latter is to

be provided by opening through the loin, in order that gravitation in

the dorsal position may be of greatest assistance. A more or less free

incision, such as is made for exploring or removing the kidney, will

usually be sufficient, but may be combined with a counteropening at any

point where the latter would be of advantage. Thus should pus present

in the groin an opening should be made both posteriorly and at the

point where it appears to be coming toward the surface.

=Tuberculosis.=--At no age are the kidneys exempt from tuberculous

lesions, although these are more frequent in the earlier years of life.

Here as elsewhere they may assume the disseminated miliary type or

occur as a solitary focus. The infection may proceed upward from the

bladder, or it may be a local expression of a widely diffuse process.

In the latter case it has passed beyond the control of the surgeon

as such, and calls for general therapeutic measures, judiciously

selected and actively maintained. Not a few cases of renal abscess, of

pyelonephritis, and even of perinephritic abscess, are due to primary

tuberculous lesions.

=Symptoms.=--About the earliest symptoms that a patient may complain

of are _thamuria_ (frequency of urination), with blood or pus in the

urine. Even at this early stage the condition is essentially surgical,

so the diagnosis should be established. Cryoscopy alone is hardly

sufficient, although if the freezing point be studied it should be

regarded along with the amount of fluid ingested and the quantity

of carbohydrates taken with the food. Ureteral catheterization is

valuable, although until it came into vogue we were content to study

the cystoscopic appearance and to judge by the ureteral orifices,

assuming that if one appear healthy and the other not so operation is

indicated.

The question of removal of a totally diseased kidney when the other is

more or less affected is one demanding greatest judgment. Some of the

more recent operators endeavor to determine this by the cryoscopic test

of the urine from the less affected organ. If this stand the test they

do not hesitate to remove the one which is totally diseased. Thus it

would appear that the ideal method is one of careful study of the urine

from each kidney, although it is acknowledged that when the question is

still in doubt the associate kidney may be explored before deciding to

remove the one most diseased.

=Diagnosis of Renal Tuberculosis.=--The most frequent and significant

symptoms of renal tuberculosis are _pain_, local and referred;

_hematuria_, _polyuria_, and _pyuria_. In young adults suffering

from bladder irritability, _painless pyuria_ usually indicates

tuberculosis of the bladder, secondary to that of the kidney, this

being particularly true when the urine is hyperacid. This urine, if

noted, will be found at first faintly cloudy or smoky, while later the

admixture of pus becomes more evident. The frequency of micturition

(thamuria, pollakiuria), which is frequently noted early, may be due

mainly to polyuria; the final test is the discovery of bacilli in the

urine. There is another form of thamuria which is associated with

tenesmus, constituting the painful cystitis of Guyon, which depends

on complications in the bladder itself. A search for bacilli is often

disappointing, and tuberculin may be used in the endeavor to make a

diagnosis, as well as animal inoculation. Tuberculin might, however,

give rise to error were there tuberculous foci elsewhere about the body.

[Illustration: FIG. 634

Tuberculosis of kidney, nodular form. (Israel.)]

_Renal tuberculosis_ may run a painless course, or it may be

accompanied by a severe renal colic or renal crises, the latter

sometimes due to plugging of the ureter with cheesy debris. Pyuria may

be masked by hematuria, the latter trifling, apparently spontaneous,

and occurring even during repose.

More accurate diagnosis can be rarely made without resort to the

cystoscope and catheterization of the ureters. When in the cystoscopic

image the ureteral orifice is enlarged, congested, and even hemorrhagic

or ulcerated, it may be regarded as evidence of tuberculous disease in

the corresponding kidney. Meyer has claimed that in the descending

form of tuberculosis the mouth of the ureter is ulcerated, while in

the ascending form it is apparently healthy. When both outlets are

apparently healthy, and urinalysis indicates renal disease, the case

must be one of ascending lesion. Fenwick has described what he calls

a “golf-hole ureter,” the orifice being dilated and patulous, and the

appearance being to him pathognomonic.

Ureteral catheterization is perhaps less necessary on the suspected

side than it is to prove the healthfulness of the kidney on the

opposite side. The disease is more common in the female, and usually

occurs in early adult life. It is more often a descending than an

ascending affection.

[Illustration: FIG. 635

Renal tuberculosis as seen on section. Papillary granulomata seen at

_T_. (Israel.)]

=Treatment.=--Radical treatment of renal tuberculosis is possible only

when the lesion is limited to one organ. What shall be done with the

kidney involved, when exposed and the disease revealed, may depend

to some extent upon the actual degree of involvement. More and more

surgeons are agreeing that anything like partial nephrectomy is of

questionable value, and that an organ _distinctly tuberculous should

be removed_. In other words, partial nephrectomy is of doubtful merit.

Of course, the kidney should be opened before its removal, unless from

its exterior it is seen to be hopelessly involved. A further question

of great importance is that of _involvement of the ureter_. With a

few associated lesions in the kidney the ureter may easily escape,

but with a kidney thoroughly degenerated, and with infected urine or

tuberculous debris passing constantly down through the ureter it cannot

escape contamination. It is not a difficult procedure, nor does it add

to the gravity of the operation, to extend the incision sufficiently

to permit not only the delivery of the kidney but the exposure at

least of the upper portion of its ureter. In this way the renal pelvis

may be opened and the ureter itself examined. When thus involved, and

especially if it be determined to sacrifice the kidney, as much of the

ureter should be removed with it as can be reached. While theoretical

considerations would always require these measures to be combined,

many mild tuberculous lesions of the ureter undergo spontaneous

retrocession after removal of the diseased kidney from which it has

become contaminated.

The incision intended to expose the ureter should begin about a

half-inch forward and in front of the lower costal cartilage, parallel

with the last rib, and terminate on a level with the anterior superior

spine, about one inch toward its inner side. This incision will then

be about four inches in length. The use of a pillow is of assistance

in the easy performance of this operation. The body should be rolled

as far as possible without losing negative pressure upon the abdomen.

The more abdominal fat there is present the further over the patient

should be rolled; a stout patient should have the hips raised from

the table by a cushion, in order that the abdomen may be pendent,

while the foot of the table is somewhat elevated and the operator is

facing the abdomen. After exposing the fat which is adherent to the

peritoneum, and the knife is laid aside, the peritoneum is separated

from the abdominal wall until the kidney and the perinephritic fascia

are recognized. Then with a short retractor the posterior edge of the

wound below the ribs is elevated, after which, under the influence

of gravity, the cavity opens widely, the fascia may be torn through,

and the kidney exposed and freed. The retractor is then removed,

the anterior edge of the wound pressed backward, and the kidney is

easily delivered from the abdominal cavity; or if its delivery be

impracticable, it may be at least so drawn up that the renal vessels

are easily exposed, tied, and divided. After their division care should

be given that the weight of the kidney does not drag injuriously upon

the ureter. The latter is then cleared of peritoneum, especially

to its outer side, by blunt dissection, after which a medium-width

Sims speculum, with a long bill, may be passed downward between the

peritoneum and the abdominal wall and made to draw the latter upward.

Thus an extensive view of the ureter is afforded, while its lower

portion may be still further freed toward the base of the broad

ligament. By a continuation of this process of separation and exposure

it is possible to release the ureter almost to its junction with the

bladder, where it is tied, its stump being disinfected with pure

carbolic.

=Syphilis and Actinomycosis.=--These lesions may be briefly dismissed

so far as they pertain to the kidneys. _Gummas_ are rare, renal

syphilis being usually of a disseminated type, which should be treated

by internal therapy, except when abscess results or when there arises

some peculiar surgical complication. _Actinomycosis_ is rare in the

kidneys, and is not recognized until the peculiar fungi are found in

the urine, or until some granuloma, developing toward the surface,

breaks down and discharges its characteristic products.

RENAL COLIC.

Renal colic implies severe and often agonizing pain, which follows

spasmodic contraction of the renal pelvis and ureter, in the effort to

expel an obstructing object from one or the other. It may be produced

by _calculi_, by _clots_ of blood, _clumps of pus and debris_, by

particles of _sloughing tissue_ (as in breaking-down tuberculous or

cancerous foci), by _extrinsic pressure_ of various morbid products,

or finally by _kinking_ or alternating stricture and dilatation of

the ureter. _Pain_ is the constant and significant feature, marked by

spasmodic exacerbation. It is usually well localized, and referred

along the course of the ureter and the cord to the testicle in the

male, with retraction of the scrotum, to the labium in the female, and

down the thigh in both sexes. With it there usually occur more or less

sympathetic disturbances, such as _nausea_, with most pronounced local

tenderness and sometimes abdominal rigidity.

=Treatment.=--Treatment, while palliative during the intensity of the

attack, should be later made radical. For the former hot applications,

morphine, and chloroform inhalations may be used. It may happen that

an almost complete inversion of the patient will be followed by

relief. Large does of glycerin, and sometimes of aspirin, will also

occasionally prove beneficial. Meantime the case should be carefully

studied and a skiagram be taken, in order that one may intelligently

advise and carry out whatever indications may be revealed.

RENAL CALCULUS.

_Renal and vesical calculi_ are the result of the precipitation of

material previously held in solution by the urine as it escapes from

the tubules, their nuclei or nidi being usually a clump of cells,

particles of blood clot or of tissue. They are composed mainly of _uric

acid_, _urates_ or _oxalates_, less abundantly of _phosphates_, and

rarely of _cystin_ or _xanthin_. They vary in size from the smallest

visible particle to those weighing ounces, and in number from one to

hundreds. They occur more often in males, and usually late rather than

early in life. They may be found in one or both kidneys. When the

latter it may be assumed that some systemic defect underlies their

formation. In shape they vary greatly, the small, sharp particles

often causing as much pain as do large stones, or even more. Diathetic

conditions produce them in some _de novo_, while in others they result

from previous morbid processes.

Small calculi escaping into the bladder cause intense _renal colic_

(see above), and, within the latter, unless they escape through the

ureter, as they usually do when small or are not retained behind a

large prostate, they increase in size, and become then the common

_vesical calculi_, those with uric acid nuclei. Calculi long present

in the kidney usually set up what is known as _calculous nephritis_ or

_pyelonephritis_. It is quite possible, however, for such a concretion

to first form within the tubules or at the apex of one of the pyramids,

so that it does not fall free into the renal cavity. In such locations

it may produce great pain, with hematuria and tenderness, yet not for

a long time escape into the renal pelvis. Such a stone may be shown

by a good skiagram. Calculi long retained will cause other troubles,

whose characteristics will be revealed by careful study of the urine,

especially of that drawn from the affected kidney, albuminuria and

pyuria often figuring. The symptoms include _pain and tenderness_,

which may be referred; _colic_, _hematuria_, and _pyuria_. Symptoms

of less frequency include _thamuria_ (sometimes painful), nausea, and

vomiting. The accompanying features include pyonephrosis, tuberculous

or movable kidney, or possibly various neoplasms.

=Symptoms.=--_Stone in the ureter_ may cause symptoms likely to be

mistaken for appendicitis, especially when lodged on the brim of the

pelvis, or an inflamed appendix may hang over into the pelvis and cause

bladder and rectal symptoms, while on palpation through the vagina the

tenderness and thickening may be misleading. In such cases the urine

offers the surest guide. Acute pancreatitis should hardly be mistaken

for renal trouble, as there would be a history of former attacks of

indigestion, probably associated with typical gallstone colic, while

the location of pain and the presence of pancreatic enlargement would

be significant. In pancreatitis, moreover, the urine might show sugar.

Renal or ureteral colic is sometimes followed by such reflex paralysis

of the bowel, with meteorism and tenesmus, perhaps even with nausea and

vomiting, as to suggest intestinal obstruction. Again, the crises of

Henoch’s purpura, and of angioneurotic edema, sometimes accompanied by

hematuria, may mislead.

Inspection of the entire body will probably reveal purpuric spots or

areas of edema.

Finally, _x_-rays afford very convenient means of diagnosis under many

circumstances, although mistakes have occurred from misinterpretation

of shadows. Nevertheless, when a well-taken picture shows unmistakable

evidence it may be considered as quite reliable.

=Diagnosis.=--In the matter of diagnosis few diseases, as Hunner has

shown, present such protean symptoms. Between calculous nephritis

and tuberculosis the only positive indication is the discovery of

bacilli in the urine or the reproduction of the disease in animals by

inoculation. Blood occurs in both, but is more likely to be influenced

by exercise in cases of stone. Pus occurs also in both, while pain is

unreliable. Palpation shows nothing, unless it may reveal thickening

of the ureter in the female as felt through the vagina. In pyelitis

the presence of a stone may cause any of these conditions, or it may

develop because of them. If trouble have begun soon after an acute

infection, or during pregnancy, it is more likely to be a case of

infected kidney. When tumor is suspected, urinary examination is the

best guide. The sudden occurrence of hemorrhages, with their abrupt

cessation, rather favor diagnosis of tumor, as does also the absence

of pus. Still the latter may be absent when the ureter is obstructed.

Intermittent hydronephrosis is usually due to kinking of the ureter

connected with a movable kidney. During the attacks the kidney will

be enlarged and misplaced, while blood may appear. With return to

place comes subsidence of enlargement, while increase in the amount of

urine is characteristic. Idiopathic hematuria or “renal epistaxis” is

sometimes connected with the chronic interstitial forms of nephritis.

The urine shows blood, if dealing with renal calculus, and bile if with

biliary calculus. In the former pain is more likely to radiate down

the ureter, while in the latter it is upward and backward. In biliary

trouble the gall-bladder may be enlarged and movable or even pendulous.

Kelly has suggested a method of differential diagnosis by catheterizing

the ureter, and forcibly injecting into the pelvis of the kidney a

bland, sterile solution. If the pain which it produces be identified by

the patient as the same which is usually suffered it may be regarded

as diagnostic; if somewhat different, then the actual attacks are more

likely to be biliary. A normal renal pelvis should hold about 7 to 8

Cc. before the patient begins to complain.

=Treatment.=--In the milder cases, and those where small concretions

are repeatedly passed, medicinal treatment may be given a trial. While

the alkalies, especially the lithium preparations, have repute in

certain quarters, there is probably nothing superior to piperazin in

its power of dissolving small uric calculi. Its physical properties

and its expensiveness, however, make it disadvantageous to use. It is

so sparingly soluble that part of the benefit obtained from it may be

due to the volume of fluid ingested with it, and to the consequent

dissolving and washing down of small particles. Glycerin is also an

analgesic here, as in biliary calculi, and a half-ounce, administered

every two or three hours, will often give relief. Attention to the diet

is also necessary, especially in acute and uric acid patients.

When there is reason to believe that the kidney contains a calculus

which cannot be passed, and especially when an _x_-ray picture reveals

such a condition, then _surgical treatment_ alone offers prospect of

complete relief. This includes _nephrotomy_ and what has been named

_nephrolithotomy_, _i. e._, exposure and opening of the kidney and

removal of its contained concretions. When these are easily felt

the procedure is simple. However when only a small concretion has

been shown in the skiagram, and it is not easily palpable, even with

the kidney between the fingers, it is sometimes a difficult matter

to locate. One method of doing this is with a small needle, passed

repeatedly in the direction of the supposed calculus--used, in other

words, as a probe. When such a stone is thus recognized it should be

removed.

In cases of long-standing, renal pelves are dilated into relatively

large sacs, containing numerous concretions, or sometimes a large

stone in branching form, resembling coral. If a considerable degree of

pyonephrosis or of disintegration accompany such a stone a complete

nephrectomy should be made. It remains, then, for the surgeon’s

judgment to decide as between nephrolithotomy or nephrectomy, a

question which will be settled, in large measure, by what has been

ascertained regarding the condition of the other organ. If considered

fully competent little hesitation need be felt in removing the diseased

one; if its condition be distrusted, then it were best to not carry

out the surgical indication, but to substitute for it good general

treatment.

MOVABLE AND FLOATING KIDNEY.

In most of the serious and in many of the milder degrees of unnatural

mobility of the kidney to which the adjectives “movable” and

“wandering” are applied, the surgeon has to deal with a somewhat

anomalous condition, which, while it attains serious and alarming

symptoms during life, leaves little evidence after death. Thus, Ebstein

found it in only 5 out of 36,000, and yet it is said to occur in at

least 20 per cent. of all women examined. In women and children the

kidneys lie lower and deeper in the gutter on either side of the spine,

beneath the seventh to the tenth cartilage, the upper end of the left

kidney belonging at the level of the ensiform cartilage. The kidneys

are supported by perirenal fascia, by the renal vessels, by pressure

of the surrounding viscera, their anterior peritoneal covering playing

but small part. Abnormal mobility below the twenty-fifth year of age

is rare; its etiology is still obscure, it being found in women at

least six times as often as in men; more commonly in those who have

borne several children, or who have become suddenly emaciated after

long illness, while in men it is most common on the left side. The

kidney is afforded a small, distinct peritoneal covering, the so-called

mesonephron, which, with its other supports, may be more or less lax,

permitting differing degrees of abnormal mobility, the milder being

spoken of as _movable_ kidney, the more serious as _floating_ kidney.

As Belfield has shown, in every case of functional disturbance of the

urinary organs the possibility that a floating kidney may be the cause

of the trouble should be borne in mind.

=Symptoms.=--The symptoms vary from vague discomfort to agonizing

pain. Ordinarily they include dragging sensation in the abdomen, with

indefinable discomfort, a feeling of weakness, sometimes radiating down

the legs and across the back, these symptoms frequently accompanied

by dyspnea, flatulence, constipation, and frequency of urination, all

of which may be intensified by increased activity. In the more severe

forms we find abdominal tenderness, severe pain and vomiting, with

collapse and the occurrence of peculiar crises, sometimes of intense

agony, which may occur gradually or suddenly, ceasing in the same

fashion. Not one of these symptoms is pathognomonic of movable kidney,

nor can they be with certainty attributed to it until the suspicion

is confirmed by physical examination. The severe crises are described

as coming on with intense pain, nausea, vomiting, collapse, chills,

and sometimes considerable temperature, especially in hysterical

subjects. Osler and Atlee think that too much stress has been laid

upon the condition, especially after the patient’s realization of it,

the severer symptoms often dating from the first knowledge of the

facts. Obviously, temporary hydronephrosis may be caused by temporary

obstruction in the ureter, from displacement, while temporary venous

obstruction may cause pain in a different way. Actual alimentary

disturbances are very closely simulated, and sometimes it is difficult

to distinguish between a movable kidney on the right side and a chronic

appendicitis.

A great deal of attention has of late been given to _nephroptosis_ and

to the effects of _enteroptosis_, and their production. The peculiar

crises were long ago described by Dittel, and include sometimes a

feeling of suffocation, with a desire to loosen and remove clothing,

when, after lying down, the kidney resumes its position. When after

urination relief quickly follows, there is much to suggest kinking

of the ureter and distention of the renal pelvis. Much less frequent

features are jaundice, from contraction of adjacent viscera, and

persistent nausea from the same result, or hematuria from a disturbed

circulation. The more marked forms in women are usually accompanied

by certain neurotic features, which give them a feature to which they

are not properly entitled, while the entire digestive process and the

vasomotor innervation of the viscera seem more or less disturbed, with

consequent toxemia.

The actual indication of floating kidney is its _discovery by

palpation_, the degree of displacement being in some cases quite

noticeable; thus it may cross the middle line, or may be felt even

in the pelvis. In the female the kidney should lie above the twelfth

rib, posteriorly, and above the costochondral border of the eighth rib

anteriorly, and, therefore, not be easily palpated during respiration.

This statement is somewhat at variance with some of those contained

in the text-books on anatomy, the diagrams being all made from male

cadavers. It is of importance not merely in locating the organs, but

in fastening them in place, as all methods thus far devised leave much

to be desired in complete replacement. A kidney prolapsed only to the

waist-line can scarcely be sutured to the loin without displacing it

even farther backward. On the other hand, the kidney which lies near

the brim of the pelvis rarely causes acute symptoms, because, supported

from below, it enjoys accommodation of its ureter to its abnormal

relations, so that hydronephrosis rarely occurs. The truth is that in

most aggravated cases of nephroptosis nearly all the viscera have been

displaced downward, and Ingall’s suggestion to fasten in place at one

and the same time the kidney, the liver, the spleen, the stomach, and

the transverse colon is well founded, although difficult to carry into

effect.

=Treatment.=--Fixation of an abnormally mobile kidney is indicated

in every case where its displacement causes unpleasant symptoms, yet

simple as it is in theory it is neither easy nor always successful

in practice. To completely restore the kidney to place is to fasten

it higher than the natural routes easily permit, and requires either

resection of a rib or fixation of the kidney to one of the lower ribs,

a method which has been recommended and practised by some operators.

Because of the disappointment so often resulting from these operations

conservative practitioners have felt that by pressure from below, as by

an abdominal binder with a suitably placed pad, the kidney could be so

pushed upward and held as to be made comfortable. This may at least be

tried in the milder cases. The supports should never be put in place

until the patient is on her back and completely undressed. This method

of external support failing or proving unsatisfactory, the surgeon may

choose from many different methods the peculiar plan for _nephropexy_

or kidney fixation which he will adopt.

[Illustration: FIG. 636

Nephropexy. Method by sutures passed through both kidney and capsule.

(Hartmann.)]

=Nephropexy.=--These methods all have in common the intent to produce

adhesions between the kidney and its normal environment, by which it

shall be held in or near its proper place and prevented from dropping.

The kidney more than any other organ is held in a cushion of fat, and

it becomes a question to what extent this mass of surrounding fat shall

be removed. To take it all away considerably complicates the procedure;

to leave it is to not furnish the firmest possible surroundings for the

purpose. The patient should be placed either flat upon the abdomen or

turned well over on the side opposite that to be operated, a cushion

or bolster being usually placed beneath the abdomen and loin in such a

way as to push upward and into prominence the side to be attacked. The

incision employed may be parallel to the spine, about three inches away

from it, and carried down to the tissues outside the quadratus lumborum

and other spinal muscles. Most operators prefer an oblique incision,

made between the lower rib and the upper margin of the pelvis, its

centre about four inches from the spine, extending in either direction

two inches or more, in order to afford sufficient access. It is carried

down until the abdominal aponeurosis and muscles are exposed. These

are then divided and the perirenal fat, which is sometimes excessive

in amount, is exposed. The deep opening should now be stretched to

a size to permit the introduction of a hand, and exploration made

for the identification and retraction of the kidney. Much aid may be

afforded in this effort by the use of the other hand upon the outside

of the patient’s abdomen, which should all have been protected and

sterilized to permit such free manipulation. Sometimes it is easy to

find such a kidney, at other times and in persons of certain build it

is a difficult matter. It lies behind the peritoneum, and this should

never be opened during the effort. More or less of the perirenal fat

may be cleared away. The more or less elusive kidney being identified,

it should be seized with tenaculum forceps, which should secure only

its capsule and not injure its substance. With these it is drawn up

at least to the wound, or in some methods, it is withdrawn through it

and delivered upon the surface of the body. If sutures alone are to be

depended upon they may be placed after any one of a number of different

methods. The older method was to place the kidney as nearly as possible

in its normal relations and then unite the deep margins of the wound to

the capsule, and perhaps the cortex of the kidney, by a series of two

or three sutures on either side, either of chromic gut or of silk. The

theoretical objections which prevail against passing sutures through

the renal cortex are hardly well founded, and stitches may be so

placed, if desired, but they should not be drawn too tightly (Fig. 636).

Senn and others have endeavored to induce the formation of dense

adhesions by packing around the kidney with gauze, left _in situ_

for several days, whose presence should provoke the formation of

granulation tissue. In theory this works well, but in practise the

presence of the gauze is painful, its removal especially so, and the

wound must be left more or less open for the purpose. Since I have

learned of the harmlessness and the advantages of decortication I have

made a practise of decapsulating almost every kidney thus exposed, and

of endeavoring to utilize a portion of the capsule for the purpose

of support, as by cutting it into strips, which are threaded into

a needle, and then passed through the tissues, thus utilizing the

capsule for suture material, or by fastening it with sutures which

are not passed through the kidney substance. All in all I have had

best results from a combination of some such method as this with one

of suspension, for which purpose tapes or gauze are used and passed

beneath the kidney--one above the hilum and one below it--after it

has been delivered well into the wound, by which it is, first of all,

lowered into the position in which it is intended to hold it and

then maintained there, the ends being left hanging out of the wound,

where they are tied over a roll of gauze or something similar. This

provides the smallest amount of gauze, whose presence may provoke

granulation tissue, at the same time proving an efficient means of

support, and leaving trifling strips to remove when the time for their

removal has come. I have usually left them in place for nine or ten

days, by which time they are comfortably loosened by the presence of

granulations around them, and consequent moisture, so that they are

easily withdrawn, with a minimum of discomfort to the patient. Da Costa

has suggested an improvement on this by sewing the ends of strips of

gauze with chromic gut and letting these sewed ends be placed beneath

the kidney. In the course of time, as the catgut softens, the union

is separated, and the strips are easily withdrawn. If there be a

tendency in these tapes to slip from their desired position, they may

be attached to the capsule by a single suture of catgut, which will

have softened and disappeared before the time for their withdrawal has

arrived. Again in many of these instances the capsule which has been

stripped off, or more or less detached, may be utilized for the purpose

of fixation by suture with its own tissue.

Nearly all of these operations are without mortality, although they

are not yet as satisfactory as could be desired, the trouble inhering

partly in the fact that the kidney is not fastened as high up as it

should be, or else not in quite the same relative position, so that

there is some strain upon its vessels or upon its ureter. Every effort

should be made to imitate the original position as accurately as

possible. Methods theoretically more perfect, yet more complicated and

but little more advantageous, include fixation of the kidney to the

twelfth rib, by suture passing through the capsule and then around

the rib. No matter what method be adopted, it is necessary to keep

the patient in bed for several weeks after these operations, in order

that adhesions may not only form but may not be stretched by too early

change of posture.

TUMORS OF THE KIDNEY.

The kidney is the site of an occasionally benign and frequently

of a malignant tumor of some of the known varieties. The simplest

forms, like the fatty and the fibrous, are uncommon and deserve no

special consideration here. There is a so-called _adenoma of the

kidney_, which does not deserve this expression any more than does

the so-called adenoma of the thyroid, in that it is not built up of

the normal type of secreting gland, but represents something more or

less similar to it, perhaps only undergoing multicystic degeneration,

its commonest expressions being of congenital origin. The consequence

is the production of the so-called _congenital adenoma_ or _cystic_

or _multicystic_ or _polycystic kidney_, in which may be seen a

conversion of original renal tissue into a mass of cysts, surrounded

by degenerated kidney tissue, all semblance to the original being

lost, and the whole constituting a partial or complete invasion of the

organ, by which sometimes its proportions are enormously increased. The

condition is essentially of congenital origin, although its serious

clinical expressions may not occur for years. The result is to destroy

the renal function, to produce a growing mass, and to constitute an

essentially surgical condition to be relieved only by nephrectomy. (See

Fig. 637.) I recall one child of twenty-three months with a tumor of

this character, of such size and extent that it could only stand erect

when wearing from its neck a sort of suspensory in which the lower

part of the abdomen was contained. I removed this kidney by abdominal

section, the child recovering, and being at that time the youngest case

that had ever survived a nephrectomy. A number of years later a similar

condition developed in the other kidney, of which the child finally

died, it having passed during the last thirteen days of its life not

more than an ounce or two of urine.

Of the solid tumors of the kidney both _carcinoma_ and _sarcoma_

occur, the former usually as a secondary growth, the latter usually as

primary, although any form may be met. The sarcomas are more frequent

in early life and in general more common. On account of the kidney

having a well-marked capsule metastasis is not so common, in the early

stages, as from some other organs. These malignant tumors may attain

great size; some grow regularly in shape, others constitute most

irregular masses. The entire organ may be involved or only a part.

There are no indicative _symptoms of renal cancer_ that may not

be met in other conditions; the development of tumor, perhaps its

displacement, pain, and hematuria, though late, and, in proportion to

the rapidity of growth, enlargement of superficial veins and general

cachexia. When the tumor is large enough to press upon the vena cava or

upon one of the common iliacs there will be edema of one or both lower

extremities. The veins of the external genitals are more likely to

suffer early rather than late (Figs. 638, 639).

[Illustration: FIG. 637

Congenital cystic kidney; exterior and internal appearance; patient

forty-two years of age. (Schmidt.)]

[Illustration: FIG. 638

Cancer of kidney, intramural, as seen after dividing the organ.

(Israel.)]

=Hypernephroma.=--There is one peculiar variety of solid tumor of the

kidney which deserves special mention, the so-called hypernephroma.

These tumors consist essentially of adrenal tissue, although when they

develop within the kidney their occurrence there is due to the presence

of aberrant rests of the original suprarenal tissue. Gravitz, in 1883,

was the first to recognize their real character. Supernumerary adrenal

rests have been met with in many parts of the body, not alone in the

kidney and perinephric tissue, but in the broad ligament, along the

spermatic vessels, in the sexual glands of both sexes, in the liver,

the mesentery, and even the solar and renal plexuses. Their occurrence

in these localities may be explained by the close relationship between

the mesonephros and the origins of these various organs. Hypernephroma

has no pathognomonic signs or symptoms. It is usually a single tumor,

although both kidneys have been affected. When the organ is not so

involved as to mask all its original features the tumor will be found

beneath the capsule, varying in size from that of a pea to that of

a child’s head, its outer surface lobulated by depressed bands of

capsule, its color lighter than that of the surrounding kidney texture,

while projecting portions will be soft and almost cystic. When met with

in other parts of the body its gross characteristics are essentially

the same. Metastasis is very common, the tumor often extending along

the walls of the veins, or even more often partially filling them than

the lymphatics. A common method of extension also is by implantation

within the peritoneal cavity; for the secondary implantation occurs

most often along some portion of the urinary tract--_e. g._, the

bladder.[66]

[66] It may assist in the recognition of hypernephromatous tissue,

after removal, to remember that adrenal tissue has the property of

decolorizing starch which has been turned blue by the addition of

iodine. Crofton has shown how there may be put into a test-tube a 1

per cent. starch solution colored with a drop of weak tincture of

iodine. If to this solution hypernephromatous tissue be added the

blue color changes gradually to a pink and then fades out.

[Illustration: FIG. 639

Infiltrating form of cancer of the kidney. (Israel.)]

Hematuria and renal colic are the most conspicuous features connected

with the growth of these tumors. The former often occurs during sleep,

and blood is passed in almost pure form, perhaps for a considerable

period of time, after which spontaneous recovery apparently takes

place, the trouble recurring at intervals.

There is but one method of treating hypernephromas, like other solid

tumors, namely, by complete extirpation, _i. e._, _nephrectomy_. Even

this may be too late, but should be undertaken, except in the most

unpromising instances. If the existence of metastatic involvement can

be determined even nephrectomy may be considered useless. (See chapter

on Cysts and Tumors.)

HYDRONEPHROSIS.

This term refers to a more or less permanent distention of the

kidney cavity by retention of urine, due to partial or intermittent

obstruction to its escape. An _intermittent_ form is common, which,

however, at almost any time may lead to some degree of enlargement,

while when the obstruction is permanent the resulting tumor becomes

practically a thin-walled cyst, which may contain an enormous amount

of fluid, more or less altered urine, which will contain, in addition

to the ordinary urinary elements, cholesterin crystals and other

adventitious products. Hydronephrosis, then, may be _congenital_ or

_acquired_ in origin, _intermittent_ or _permanent_ in character, and

_unilateral_ or _bilateral_ in location. Among the acquired causes

are strictures of any portion of the urinary tract below, either in

the ureter, the prostate, or the urethra; tumors of any kind making

pressure; movable kidney which permits of kinking; tuberculous diseases

which lead to chemosis of the mucosa and consequent obstruction; renal

calculi which plug the ureter; foreign bodies, blood clot, and the like

(Figs. 640 and 641).

[Illustration: FIG. 640

Hydronephrosis from obliteration of ureter by tuberculous disease.

(Tuffier.)]

[Illustration: FIG. 641

Hydronephrosis in first stage of development. (Rayer.)]

[Illustration: FIG. 642

Operative treatment of hydronephrosis or pyonephrosis. (Hartmann.)]

Until the infectious or suppurative element be added the urine is

in these cases but little changed. When infection is added the case

becomes one of _pyohydronephrosis_, and perhaps finally one of distinct

_pyonephrosis_. The symptoms produced at first are not very pronounced

and will vary with the exciting cause. If the result of acute

obstruction, renal colic is perhaps the most significant. When this is

accompanied by tumor in the region of the kidney the interpretation of

the phenomenon is easy. Sudden decrease in size of such tumor, with

unusually great escape of urine, is also pathognomonic of intermittent

hydronephrosis. The discovery and the history of a gradually increasing

tumor in which, when large, fluctuation can be determined, and in

which fluid is easily found with the aspirating needle, will permit a

differentiation of these pseudocysts from solid tumors of the kidney.

They are to be distinguished from _ovarian cysts_, from general

_ascitic accumulations_ within the abdomen, and from _perinephritic_

and _spinal abscesses_. Their location, which corresponds so closely

with that of the kidney, especially while they are small, their

gradual growth, the displacement of the abdominal viscera forward and

to their inner side, their enlargement downward and their fluctuating

character will usually provide features by which they may be accurately

recognized.

=Treatment.=--The _treatment_ of intermittent hydronephrosis in its

earlier stage may be accomplished by some measure less radical than

nephrectomy or nephrotomy, particularly when due simply to abnormal

movability or to pressure of some extrinsic growth. Hydronephrosis due

to obstruction by renal calculus may be relieved by removal of the

obstructing stone, but a hydronephritic cyst, which has attained large

size, in which practically all semblance to secreting kidney structure

has disappeared, should be _extirpated_, unless this should entail

too formidable an operation, in which case it should be freely opened

and drained until such time as it has contracted to a size justifying

enucleation (Fig. 642).

THE URETERS.

There are a few morbid surgical conditions of the ureters, so distinct

from those of the bladder below or the kidneys above as to require

separate consideration here. They are frequently involved in the

pyogenic and tuberculous infections, which spread along them in either

direction, but the chief surgical diseases deserving mention here are

_stricture_ and _calculus_.

STRICTURE OF THE URETER.

Stricture of the ureter may result from intrinsic or extrinsic lesions.

Thus it has been injured in operations upon the pelvic viscera, as in

parturition, and it is not infrequently pressed upon by neoplasms;

but the majority of its contractions are cicatricial, and are

consequences of ulceration or injuries done by calculi. Stricture of

the ureter is to be recognized rather by its consequences--_i. e._,

hydronephrosis--than by more direct symptoms. Its accurate location

is now possible by the use of the cystoscope and the ureteral bougie

or catheter. When by the cystoscope no urine is seen escaping from

the ureter one naturally infers its complete obstruction--in fact,

the degree of the latter is fairly estimable with this instrument.

However, with the passage of a bougie the trouble may be found. This

is particularly of value when the lesion is an impacted calculus, for

it indicates to the surgeon the level at which he should direct his

operative relief, a matter which may also be decided by a skiagram.

While in the hands of experts dilatation of the ureters may be

accomplished from below, it is usually beyond the ability of the

average surgeon. He has to decide, then, as to whether the ureter

should be exposed along its course, from the loin, extraperitoneally

along the groin, or by abdominal section. A ureter hopelessly entangled

in a mass of cancer may be turned into the other ureter or into the

bowel. A ureter fixed in a narrow, cicatricial band may be divided and

its upper end turned into the tube below the stricture by a process of

transplantation or anastomosis, which is one of the feats of modern

surgery; but a ureter hopelessly involved for a considerable portion,

or hopelessly diseased, will require nephrectomy, as the kidney above

it may be compromised and can probably be well spared.

Calculi impacted in the ureter are most commonly arrested at those

points where its caliber is normally smallest, just below its origin,

at the pelvic brim, and just above its orifice. The symptoms of

impaction are those of renal colic, already considered. It should be

sufficient that extreme pain and the escape of pus and blood in the

urine, accompanied by more or less distention of the kidney above,

are noted. If there be a history of previous attacks of this kind,

with the passage of small calculi, the diagnosis may be regarded as

positive. This may or may not be confirmed by the _x_-rays, or by the

catheterization of the ureter from below.

Gibbon has suggested _intra-abdominal exploration_ and palpation of

the ureter for the discovery and location of impacted calculi, and

recommends that when discovered they may be removed by extraperitoneal

incision, which may be lumbar, iliac, inguinal, vaginal, or even sacral

or rectal; while with the advantage of combined manipulation, the

operator having one hand in the abdominal cavity, the actual work is

more rapid and certain.

This procedure is not to be advised in every case by any means, but may

prove of advantage in doubtful cases, and especially in those where,

when the abdomen has been already opened, a stone is accidentally found

in the ureter, since when the latter is opened extraperitoneally it is

rarely necessary to suture it.

The _non-operative treatment of ureteral calculi_ has been considered

when speaking of renal calculi. The _operative treatment_, inversion

of the patient having failed, may consist of exposure of the upper

two inches of the tube, by an incision parallel to the twelfth rib,

and carried well forward and downward toward the middle of Poupart’s

ligament. Through such an incision the whole length of the ureter may

be reached. The opening is made down to the peritoneum, which is then

pushed toward the median line. On its posterior surface, adherent to

it, will be found the ureter. At the point where the stone is impacted

the ureter is to be divided and the stone removed. In theory sutures

should be inserted; in practice, they are rarely needed, as these

incisions usually heal kindly without them.

A stone impacted at the vesical orifice of the ureter may, in the

female, be removed after such dilatation of the urethra as shall permit

access, or it may be removed through the vault of the vagina. In the

male only the most expert manipulators within the bladder will attempt

its removal in this way without at least a perineal section.

OPERATIONS UPON THE KIDNEYS AND URETERS.

In addition to the operative procedures already described the principal

operation upon the kidney is _nephrectomy_. While this may be

_partial_, under rare circumstances, the procedure is so essentially

similar to the complete operation that it is only necessary to say that

if a portion of the kidney be removed, bleeding from spurting vessels

should be arrested by ligature, while the oozing, at first pronounced,

will soon subside under the application of hot water, after which

absorbable sutures may be used in sufficient number to approximate the

parts.

[Illustration: FIG. 643

Position of patient and various lines of incision for nephrectomy and

other operations upon the kidneys. _A_, the favorite method of approach

for most purposes. (Hartmann.)]

_Total nephrectomy_ is usually done by the lumbar route, the kidney

being exposed by an oblique incision extending obliquely downward from

near the spine, parallel to the lower rib, between it and the crest

of the pelvis, and as far forward as may be required for the purpose.

For removal of a large solid tumor a large opening should be made, and

the above incision may be extended in any required direction, or an

additional cut may be made wherever required. In fact, in attacking

some of the very largest growths it becomes necessary to apparently

almost bisect the patient in order to furnish sufficient space. As

the mass to be attacked lies behind the peritoneum it is rarely

necessary to open the peritoneal cavity. This is usually done only

by inadvertence or because of density of adhesions, and the effort

should then be made to at once close it temporarily or permanently.

Especially should every attempt be made to prevent contamination when

dealing with tuberculous or suppurative renal disease. Ordinarily the

abdominal opening does not extend nearer to the spine than the border

of the spinal muscles. These may, however, be divided if necessary. So

also may the deep fascia be divided in any direction, and, in fact,

the last rib may be removed _in toto_ if required. The kidney or the

tumor, having now been reached, should be isolated. If the condition be

cancerous as much of the surrounding tissue should be removed as the

case will permit; if otherwise, an enucleation of the kidney from its

more or less infiltrated bed will be sufficient. It is usually removed

with its capsule, but sometimes the latter is so adherent that it is

easier to enucleate the kidney itself from within it. Adventitious

vessels may enter the kidney, more especially from below. The surgeon

must be prepared, then, at any time to clamp and secure them if found.

Sometimes enucleation of the kidney is exceedingly easy; at other times

old adhesions or surrounding infiltration make it a matter of great

mechanical difficulty. The intent is to not only isolate it, but to

make such exposure of its pedicle that one may be securely protected

against hemorrhage. Incidentally the ureter should be examined from

above, by passage of a probe, or by injecting a colored solution, in

order to know later if it passes freely into the bladder. It is the

accurate securement of the renal vessels which is perhaps the most

necessary feature of the operation and upon which most depends. When

this is made impossible by extraordinary circumstances expedients must

be adopted, as, for instance, the use of an elastic ligature--_i.

e._, a piece of small rubber tubing, drawn tightly around the base

of the mass and secured by clamp, ligature, or suture, the intent

being to leave it for at least two or three days until it shall have

accomplished its work, and then either to remove it or to allow it to

loosen itself in time and come away.

[Illustration: FIG. 644

Nephrectomy. Complete delivery of kidney and ligation of its vessels

and ureter. (Hartmann.)]

Under some circumstances the surgeon may so complete the nephrectomy

that the external wound may be closed without drainage; but when there

has been contamination, as by escape of contents, either purulent

or urinary, or when a considerable mass of tissue has to be left

enclosed within an elastic ligature surrounding the stump, then an

opening should be left in order that slough may easily escape and

ample drainage be afforded. A reliable ligation of the renal vessels

should be made, which is best done with at least two ligatures, taking

the pedicle in parts, or else carefully isolating the vessels when

sufficiently exposed, and tying each one of them separately, after

which the whole group may also be enclosed in a single ligature. A

few operators have reported such accidents as tearing the renal vein

from the vena cava, and such a wound has been successfully sutured,

the patient recovering; this requires, however, both coolness and

resourcefulness in the presence of serious difficulty and danger.

Certain dense tumors can be removed by process of morcellation, _i.

e._, removal of a portion at a time, the separate pieces being cut away

with scissors or knife, as may be the more convenient, and hemorrhage

being controlled by clamps.

The _anterior_ or Trendelenburg route is rarely selected for

nephrectomy, but may be adopted when this procedure is made a part of

other abdominal work, or may be necessitated by the presence of a large

tumor in a small abdomen, as, for instance, in children. The abdomen

will be opened as for any abdominal tumor, either in the middle or to

one side, as may seem best. The tumor itself will so far displace the

viscera as to perhaps present at once beneath the knife. It may be

necessary to go through the peritoneum twice. After being thus exposed,

and the abdominal cavity protected, the balance of the operation is

again a process of enucleation, with securing access to the pedicle of

the tumor, where its vessels and the ureters may be found. These again

are ligated and the mass removed as though it were from the peritoneal

cavity. Posterior drainage may be added, although rarely necessary.

Other operations have been suggested to meet the needs of individual

cases. Thus _pyelectomy_, or removal of a portion of the dilated pelvis

of the kidney, has been performed by Murphy and others, the process

being essentially an excision of a portion of the sac wall and its

retrenchment by sutures. Plastic attachment of the dilated upper end

of a ureter to the floor of the renal pelvis has also been effected

in much the same way, as in a case reported by Murphy, where, after

opening the sac of the pelvis, the ureter was slit for a considerable

distance, while at the lower angle a V-shaped piece of the sac

was fastened into the ureteral opening, thus making a funnel-like

communication.

Again, as illustrative of some of the radical suggestions of recent

years, Watson has proposed that in instances of hopeless bladder

conditions, where the patient is made miserable, there should be a

turning out of both ureters on the loin, and the formation of two

_ureteral fistulas_, after which the patient may wear a drainage

receptacle, and in this way enjoy a comfort otherwise unattainable. He

has reported the case of such a patient, who has thus passed all the

urine for four years, and urine from one side for eleven years, who was

otherwise in comfortable health.

[Illustration: FIG. 645

Longitudinal suture of ureter. (Hartmann.)]

[Illustration: FIG. 646

Implantation or invagination of ureter with fixation and then with

circular sutures. (Hartmann.)]

[Illustration: FIG. 647

Longitudinal incision and transverse suture of ureter for stricture,

similar to the pyloroplastic method of dealing with pyloric stenosis.

(Hartmann.)]

=Operations upon the Ureters.=--The surgery of the ureters is also

quite modern, and has been worked out in the experimental laboratory.

That ureteral tissue will heal has been proved by Murphy, who has

remarked that “The peritoneum is the only tissue that unites as kindly

as does the ureter.” After accidental injuries during other operations

the ureter may be sutured almost as though nothing had happened. These

sutures should be made with fine round needles, and be placed closely

together. They should be made of fine silk or thread.

Not only end-to-end union but lateral anastomosis and even more

ingenious methods of transplantation and implantation are now in

vogue. Figs. 645, 646 and 647 illustrate some work in this direction,

and show what may be done by work quite similar to that done upon

the small intestines or the bloodvessels. More complete instances

of transplantation have been effected in connection with exstrophy

and carcinoma of the bladder, where, for instance, the ureters

individually, or the base of the bladder containing the ureteral

orifice, have been dissected out and implanted in the colon or the

rectum.[67]

[67] In one case I carried out the following procedure, necessitated

by cancer involving the urethra, the base of the bladder, the

rectum, and the whole floor of the pelvis, in a female patient,

the disease having attained a degree making urination or even

catheterization impossible. I opened the abdomen, dissected out the

_right ureter_ from the bladder, _implanted it into the appendix_,

and then dissecting the left ureter in the same way _implanted it

in the right_, the intent being to direct the whole urinary stream

into the colon and thus spare the bladder. The operation was not

finally successful. I afterward found that this method had been tried

experimentally by Jacobson, of Toledo, but without success.

CHAPTER LV.

THE BLADDER AND PROSTATE.

Methods of recognition of surgical diseases of the bladder have been

vastly improved, as well as complicated, within the past few years. The

bladder has now been made accessible not alone to touch, as through

the rectum or vagina, or by incisions above or below the pubis, but

to sight, through the use of the _cystoscope_. It is furthermore

possible to detect foreign bodies within it by the Röntgen rays.

_Palpation_ is chiefly of value in thin persons, or when the bladder

is greatly distended; still, infiltration of the base of the bladder

can be detected through the vagina or through the rectum, as can also

certain foreign bodies. Much of value is learned by both chemical and

microscopic examination of the urine. This may be passed by the patient

or withdrawn by the catheter. It has already been indicated how much of

value can be learned by separating the urine drawn from each kidney.

The difficulties of this procedure are greater in the male than in

the female, owing to the complications in the requisite manipulation

of the instruments. Nevertheless there is no accurate method of such

estimation save by ureteral catheterization. The method of Harris,

by the use of the so-called segregator, is of occasional assistance,

but is never accurate nor always satisfactory. If the catheter alone

be used it should be of metal, if it be desired to have it serve the

purpose of a probe, as in the search for a foreign body (calculus

and the like) or as a means of estimating the size and shape of the

bladder. For the latter purpose an ordinary sound will serve as well,

preferably one with a short beak, ordinarily known as a stone searcher.

In cases of prostatic enlargement it is of great advantage to estimate

the amount of residuary urine after the patient has apparently emptied

his bladder. This may be withdrawn by a sterile catheter under aseptic

precautions. The use of the catheter is also necessary for lavage of

the bladder, a measure of great value in many cases.

The attempt will not be made here to picture nor go into a minute

description of the various forms of the _cystoscope_. Their use, like

that of the ophthalmoscope, requires special aptitude and training.

With the latter they are of great value; without them they confuse

and complicate. The cystoscope may be used for ordinary purposes of

inspection, for aid in introducing the ureteral catheter, or even

for photographic purposes, for it is now possible with the latest

instruments to photograph the image thus obtained of the bladder

interior. To one not accustomed to viewing the field seen in such an

instrument these revelations are of little interest. To the expert,

however, they may be made of the greatest value. Without further

description, then, allusions made below to the use of the instrument

must presuppose some familiarity with it, and the advantages and even

necessity of securing special training in its use.

CONGENITAL MALFORMATIONS OF THE BLADDER.

The lesser malformations of the bladder include mainly irregularity

in shape or the formation of _diverticula_, which are not extremely

rare. These are especially likely to be met during hernia operations.

I have repeatedly in operating for inguinal, and once in operating

for femoral hernia, found a diverticulum of the bladder complicating

the situation. Its possibility, then, should be borne in mind. It may

be thin and lie in such close relation to the hernial sac as to be

mistaken for the latter. When opened urine will escape and contaminate

the wound. It would probably be best to close the bladder opening and

discontinue the operation rather than run the risk of contamination of

the peritoneal cavity, postponing further work for a few days. As the

result of allantoic defects a _double bladder_ may be met, each perhaps

having one ureter opening into it. More or less complete partitions

in the bladder are more frequently met. These conditions could not

be appreciated previous to opening the viscus or the use of the

cystoscope.

More complete forms of acquired vesical hernia may be found in such

conditions as _cystocele_, common in women after perineal lacerations,

and frequently constituting a most serious condition.

=Ectopia or Exstrophy of the Bladder.=--By far the most serious and

extensive of the congenital malformations are those constituted by more

or less complete defects of the anterior portions not alone of the

bladder, but of the abdominal wall which should cover it, and which

are known as _ectopia_, _exstrophy_, or _extroversion of the bladder_.

Of this condition there are different degrees, from a small cleft just

behind the symphysis pubis, to that which is complicated by prolapse of

the remaining posterior wall, the umbilicus being situated just above

it, while the pubic arch itself is defective or rudimentary. Thus in

the male there is usually _epispadias_ of a more or less _rudimentary

penis_, while in the female the _clitoris_ is _cleft_ and the _vulva

more or less opened_, the urethra being defective or entirely

wanting, the vagina often small, and the uterus generally infantile.

Extreme cases of this condition constitute one of the most serious

and deplorable congenital defects which are not inherently fatal.

Obviously, with these conditions, there is constant escape of urine,

usually with complete mechanical impotence, although in the female

the ovaries are usually present, and practically always the testicles

in the male. In the latter the opening of the seminal ducts may be

frequently seen on the floor of the urethra, more or less concealed by

folds of cystic mucous membrane. The condition is much more frequent

in males than in females. The prostate is usually at least rudimentary

and may be wholly wanting. Occasionally the testicles are undescended.

Double uterus has also been seen in these conditions.

Regarding its causes there is but little known. Doubtless these have

to do with allantoic defects, but the allantois is such a temporary

organ that there would seem to be some other contributing cause not yet

recognized.

Among its most distressing features are not only the lack of control

of urine, but the irritation of the exposed mucous surfaces consequent

upon friction with clothing, or decomposition of urine and consequent

uncleanliness. There is, therefore, nearly always ulceration, with

extreme irritability and more or less constant suffering. It is not

strange, then, that for its relief surgeons have taxed their ingenuity,

or that adult patients, finding the conditions unbearable, are willing

to submit to even extreme measures.

=Treatment.=--So many operative measures have been devised that it is

impossible to include them all. First of all the procedure should be

adapted to the particular case. Much will depend, for instance, upon

the extent of the defect in the abdominal wall, or in the pubic arch,

and in the male upon the rudimentary condition of the penis or the

extent of the urinary canal.

Operations for this condition may be divided into _palliative_ and

_radical_--_i. e._, those which are intended to make it more tolerable

and those which are really entitled to the latter term. Thus if only

the exposed mucous surface can be covered with a skin covering, the

condition may be mitigated since a urinal or some device may be worn by

which its worst features may be controlled. Trendelenburg has recently

called attention to the fact that a wide separation of the pubic arch

not only weakens the pelvis, but constitutes a serious difficulty in

closing the defect. He has, therefore, combined direct operation with

separation of the pelvic bones at the sacro-iliac joints, afterward

enclosing the pelvis in a comprehensive bandage, or suspending the

patient in an apparatus in such fashion that the bony defect in front

shall be narrowed, if indeed it be not completely obviated. This, of

course, is a measure to be carried out in the early years of childhood;

in connection with it the bones may even be wired at the symphysis. In

fact immediately after the birth of such an infant the attempt should

be made to narrow the pelvis, by surrounding that part of the body

with a wide rubber band, which shall influence growth without too much

interfering with nutrition. Later subcutaneous osteotomy may be done if

necessary. At all events, the growing pelvis should be surrounded with

an enclosure by which a constant influence may be maintained.

The various _plastic operations_ for this defect have the common

purpose of affording a covering, which must unfortunately be without

a sphincter to guard the outlet of the cavity. The best that can be

accomplished, then, by plastic methods is the formation of a more

perfect cavity without affording sphincteric control. A theoretically

ideal method would be one which should permit raising of skin flaps

around the margin of the defect, and so turning them in that the skin

should vicariate as mucous membrane. These flaps when united, and

the anterior wall when thus formed, could be covered by other flaps

or by skin grafts; but from these flaps hairs will grow into the

bladder. These will become encrusted with urinary salts and an amount

of irritation be produced which may become not only intolerable but

locally destructive.

In the selection of any plastic method much will depend on the size

of the defect and its completeness, the condition of the surrounding

wall, and varying complications in the surrounding structures. The

general method above suggested will answer especially for the smaller

exstrophies. Beck has suggested an excellent device, namely, the

dissection from the pubes of the recti muscles, their insertions being

severed, and the partial division of the transversalis fascia until

the muscles are so mobilized that they can be reflected and united,

thus forming an anterior bladder covering. By a second operation these

partially formed flaps may be again dissected off from the wall and

a complete osteoplastic covering afforded. Practically no operation

for extroversion can be completed in one sitting. Frequently repeated

efforts have to be made, a little being accomplished at a time. One

of the greatest difficulties met with is securing primary union along

surfaces more or less bathed or in contact with escaping urine. These

flaps, even if united, may separate in a few days as a result of

this urinary maceration. Against this there is but little possible

provision, save perhaps by catheterizing both ureters, and emptying

them into a distinct receptacle.

[Illustration: FIG. 648

Roux’s autoplastic method of raising a perineoscrotal flap with which

to cover the defect. Lines of incision. (Hartmann.)]

[Illustration: FIG. 649

Roux’s autoplastic method of raising a perineoscrotal flap and its

fixation. (Hartmann.)]

More complicated methods of furnishing a complete cavity have been

devised by Rutkowski and Mikulicz, both of whom have suggested to use

a small loop of small intestine wherewith to complete the bladder

cavity. In each of these methods the abdomen is opened, a loop of bowel

brought down, a small portion completely separated by double division,

end-to-end anastomosis of the main part being then made, while the

separated part is in one method closed at one end, while the other

end is fitted over the exposed bladder surfaces as a sort of cap. The

method is exceedingly complicated and hazardous, and depends for local

success upon a sufficient blood supply to the intestinal loop, which

should be carefully ensured by caring for its vessels and mesentery. It

has, nevertheless, been successful.

A far simpler method, perhaps the simplest of all, is that of

Sonnenburg, which consists in extirpation of the bladder proper,

with plastic closure of the opening, while the ureters are carefully

separated and sutured into the upper portion of the urethral gutter.

This removes all urinary cavity and provides only for continuous

escape; but this latter is now provided in an accessible and convenient

place, while the wearing of a urinal permits the achievement of the

main purpose of the operation. Sterson operates upon young girls by

suturing the loosened ureters to the labia minora, which are then sewed

together in the median line, after which a urinal can be worn.[68]

[68] Cantwell has suggested the following method for bladder

exstrophy, namely, to pass catheters through a perineal fistula up

into the ureters, then to dissect off the bladder wall, bringing it

over a small rubber balloon, pushing the whole into position, and

uniting the abdominal wall in front.

It has occurred to many operators to more completely divert the urinary

stream by displacing the ureters and turning them into the rectum or

the sigmoid. Operations for this purpose have been described especially

by Maydl (Fig. 650), and by Moynihan, while modifications have been

suggested by many others. In practically all of these procedures

catheters are first passed into the ureters for their identification

and control. Some would dissect out the trigone with both ureters, and,

making a sufficiently large opening in the rectum, would transplant

it in its entirety within that cavity, closing the opening. Moynihan

improved on this by making a vertical incision and entirely dissecting

away the bladder, separating it also from the prostate, thus completely

isolating it. Then the portion containing the ureters is held upward,

while at the bottom of the wound the rectum can either be seen or made

visible. The peritoneal reflection is then lifted upward from the

front of the rectum, which is opened along its anterior surface by an

incision perhaps three inches in length. Into this opening the bladder

is placed, being so reflected that its former anterior surface now

looks posteriorly. The ureters, instead of passing forward, now pass

backward and the catheters contained within them are passed into the

rectum and out of the anus. The edge of the bladder and the cut edges

of the rectum are carefully sutured, after which the abdominal wound is

closed. The sphincter is then stretched, while the catheters remain in

the ureters for four or five days.

[Illustration: FIG. 650

Maydl’s operation; diversion of ureters into rectum. (Hartmann.)]

A choice may be made, then, between some such method as that last

described or that of Peters, who dissects out the ureters, retaining

only a small circular patch of bladder wall, which is folded around the

orifice of each, the rest of the bladder being extirpated. Each ureter,

with its button of bladder wall, is then drawn through a small slip

in the rectal wall, made large enough to admit it, and the end of the

ureter is then left hanging for 1 or 2 Cm. into the rectum. It would

probably be better to hold the ureters in place by a stitch rather than

run the risk of their retraction; but care must be taken that these

stitches make no unnecessary constriction. Others have substituted the

sigmoid for the rectum, the procedure being otherwise the same, all of

these rectal implantations having for their purpose the utilization of

the rectum as a cavity, which may not only contain urine, but retain

it reasonably under control. In many respects they would be ideal were

it not for the attendant dangers. These are (1) those immediately

connected with an operation which is serious, and (2) those connected

with secondary infection of the kidneys, which seems to occur in almost

all cases, no matter how apparently successful at first.

INJURIES TO THE BLADDER.

Injuries to the bladder proper may be accompanied by those of the

parts without, or may be isolated. They divide themselves mainly into

_ruptures_ and _lacerations_, or _penetrations_ directly connecting

with the exterior. Among the causes which predispose to rupture and

other injuries may be mentioned intoxication, partly because it is

often accompanied by overdistention, and partly because of the partial

or incomplete insensibility of the patient. _Distention_, no matter how

permitted, is an important predisposing cause. The injuries usually

include blows, falls, and crushes, and gunshot or other perforations.

The location of the rent is more commonly in the upper and posterior

portion of the bladder--_i. e._, in its weakest part. Such tears

may vary from one-half to four inches in length. When _accompanying

fracture of the pelvis_ the peritoneum is more likely to be injured.

The most _significant symptoms_ are a desire to urinate and inability

to do more than perhaps expel a few drops of bloody fluid. Of course

the passage of any blood or bloody urine will suggest the occurrence of

such an injury. Patients are usually unable to stand upright, and also

show a strong tendency to flexion of the thighs. The introduction of a

catheter and the withdrawal of bloody urine do not necessarily settle

the question as to whether there has been any possible laceration.

Some surgeons have taught that normal urine is comparatively harmless

and that it is no more likely to produce infection than the catheter

used for diagnostic purposes; but this is not safe teaching today. A

clean metal instrument is of no more danger than a clean probe under

other circumstances. Weir has suggested a valuable test, consisting

of removal of all the urine possible, after which a measured quantity

of sterile fluid is injected. If on using a catheter again this be

all recovered it may be assumed that the bladder is not ruptured,

otherwise the contrary. If hours after the injury a catheter be used

and no urine secured, this fact will be most suggestive. The cystoscope

is usually disappointing, since a bladder so injured cannot often be

satisfactorily examined.

Another class of serious injury to the bladder includes the

_perforations_, such as may be effected by gunshot or stab wounds, or,

as in one case of my own, where a lad sat down upon an iron spike,

about three-quarters of an inch square and nearly six inches in length.

The point of the spike entered the anus, and the consequence of the

injury was a perforation of the anterior wall of the rectum and the

posterior wall of the bladder, with injury to its anterior wall without

complete perforation. Prompt operation saved this case, as it will most

such instances, although it was shown that a piece of his trousers had

been carried into and left in the bladder. I opened the abdomen above

the pubis, to be sure that the peritoneum was not injured, and then

drained by a tube passed into the anus and out just above the pubis,

after removing the piece of cloth. Prompt recovery followed.

The bladder may also be injured by rude manipulation of instruments,

especially the metal catheter, by one unaccustomed to using it, or when

serious difficulties are offered by prostatic enlargement.

=Treatment.=--Diagnosis or even serious suspicion of such injuries to

the bladder as above described require either perineal or abdominal

section, the choice of the procedure being based upon circumstances.

If there be reason to suspect intraperitoneal extravasation, then the

abdomen should be opened, carefully cleaned, the bladder rent sought

and sutured, the mucosa being first closed with hardened gut, while

the peritoneal aspect may be sutured with silk or thread. The bladder

should be drained, at least by retention of a catheter, passed if

necessary by perineal section, and the abdomen drained. In the female

drainage may be made through the cul-de-sac. If there be urinary

extravasation behind the perineum, then perineal section should be

made, and the bladder, thus freely opened, should be drained with

a sufficiently large tube; while in the female it will probably be

sufficient to dilate the urethra and insert a tube of sufficient size.

It is not always easy to discover an opening placed posteriorly in the

bladder wall, and after a wide exposure, with emptying and cleansing

of the pelvis, it may be of great assistance to place the patient in

the Trendelenburg position. Under rare circumstances the rent may be so

placed as to justify a suprapubic drainage of the bladder.

FOREIGN BODIES IN THE BLADDER.

Foreign bodies other than calculi occur in the bladder in consequence

of both accident and of design. The former are, _e. g._, represented by

pieces of broken catheter, while the latter are materials introduced

from without in consequence of sexual perversion, during intoxication,

or from some other vicious tendency. The latter occur more often in

girls and women, the former more often in men. In such a collection

of cases as was made by Poulet (_Foreign Bodies in Surgery_) almost

every imaginable object that could be introduced into the bladder is

mentioned. Some of these have slipped in accidentally after external

manipulation, as in masturbation, and some have been deliberately

introduced. Perhaps as common an object as any is the ordinary hairpin.

It is the short urethra of women which is made the much more frequent

resort for such practices than the long urethra of men, in which latter

foreign bodies are often entangled or arrested before they reach the

bladder.

Any object allowed to remain in the bladder will serve as a nidus for

the formation of a calculus, which will form in time, and it may result

that not until the removal of the calculus and examination of its

interior structure will the original foreign body be found.

All objects of this kind should be removed as early as possible

after their introduction. Such removal may be easy and accomplished

by dilatation of the female urethra, with or without the use of the

cystoscope; or the bladder may require to be opened, either above the

pubis, through the perineum, or through the vagina, in order that the

object in question may be extracted.

INCONTINENCE, RETENTION, AND SUPPRESSION OF URINE.

Students often confuse not only terms but conditions, and it is

necessary to be accurate in teaching regarding these subjects.

_Suppression of urine_ is purely a matter of cessation of renal

function, and _has nothing to do with the bladder_. _Retention of

urine_, on the other hand, has nothing to do with the kidneys, but is

purely a bladder affair. It may be due to spasm of the bladder outlet,

or to its obstruction by calculi, other foreign body, or by prostatic

enlargement, or it may be a consequence of paralysis of bladder muscle.

Such retention is the inevitable consequence of fracture of the spine,

since paraplegia is to be expected in such cases, and the condition is

to be atoned for by careful and _regular catheterization_. Retention,

again, is occasionally seen in hysterical patients. It furnishes the

distressing and sometimes permanent or even fatal consequences of

prostatic enlargement in old men. _No matter how produced, it must be

relieved_, for urine tends to accumulate and to distend the bladder,

which will finally burst unless the difficulty be sufficiently overcome

so that urine may in some way escape. Distention of the bladder under

these circumstances is recognized by the formation of a rapidly

increasing tumor, which finally rises to the level of the umbilicus,

fluctuates, and is accompanied or not by pain according to the nature

of the cause of retention. In paralytic cases there will be little or

no pain. In obstructive cases it will be agonizing.

By natural efforts final rupture of the bladder is usually prevented,

as after a certain degree of distention has been attained urine begins

to escape drop by drop. This is simply an _expression of an overflow_,

and is not to be confused with incontinence in the proper sense of

the term. It may be spoken of as _stillicidium_, due to retention.

The young and indifferent practitioner may mistake this escape of

urine for incontinence, which would be a most serious error. Under any

circumstances, when such a condition may possibly occur, the lower

abdomen should be palpated, when the presence of a distended bladder

should be instantly recognized. The first indication is for its prompt

relief by the use of the catheter, while the necessary catheterization

should be done with the usual precautions. When the passage of an

ordinary instrument is made difficult or impossible the cause of the

retention is usually thereby revealed, and may be shown to be so

serious as to necessitate further operative procedures.

When the bladder is distended and no catheter can be introduced it

is advisable to _aspirate_, the aspirating needle being introduced

through the sterilized skin just above the pubis, its point directed

toward the centre of the mass formed by the distended bladder. Repeated

aspiration may be necessary, and it has been suggested to make more

or less permanent use of such a tube or hollow needle. At present no

surgeon would continue this as a permanent measure, but simply as a

temporary relief, even if repetition be necessary, until more radical

procedure can be carried out. Whether this be the removal of a foreign

body or calculus, or of an enlarged prostate, it is indicated just the

same, the only exception to this statement being those cases already

too seriously involved to justify more than perineal section (cystotomy

for drainage). _Retention of urine, then, is always a preventable

condition, and its continuance is inexcusable._

_Incontinence_ implies a paralytic condition, usually of the expulsive

muscles, but sometimes of the sphincter apparatus in either sex, by

which urinary control is lost and urine escapes involuntarily. It

may be a temporary and occasional phenomenon, occurring under the

influence of strong excitement or during sleep, especially in children,

or it may be due to spinal disease or traumatisms, with paralysis of

the lower segments of the cord and nerves given off from them. When

originating in the latter way it is usually a hopeless condition,

but _nocturnal incontinence_ of children, or even of adults, or

that due to hysterical or other neurotic conditions, may usually

be benefited. For this purpose the surgeon should search for the

cause from which the reflex proceeds. This may be extreme acidity of

urine, the irritation of a tight prepuce in either sex, the presence

of worms, intestinal disturbances, or any one of a great number of

possible causes of disturbance of nerve control. Some of them permit

of surgical relief; others require simpler measures. Children thus

suffering should be given no fluid late in the evening, but should

be made to empty the bladder before retiring, and perhaps be aroused

once or twice through the night for the same purpose. In all cases

the urine should be examined and hyperacidity overcome. All forms of

genital excitement should be obviated. In the adolescent and in adults

thus annoyed, and in the insane, it has been shown to be of great

benefit to make a few intraspinal injections of sterile salt solution,

as for local anesthetic purposes, a little cerebrospinal fluid being

first withdrawn, and then from 2 to 10 or 15 Cc. of the solution being

introduced. This seems to have been empirically suggested by a French

surgeon, but has been found of value by Valentine and others, including

the writer.

The above forms of incontinence are to be distinguished from intense

irritability of the bladder, with frequent calls to empty it, which

accompany many such conditions as cystitis, tuberculosis, tumors,

calculi, and the like. This is the extreme irritability of local

disease rather than true incontinence. But there is also a form,

in women, characterized by falling away of the urethra and neck of

the bladder from the pubis, due usually to injuries received during

parturition, with consequent sacculation or dilatation of the urethra

and formation of a cystocele. (Dudley.) This may also be associated

with other results of perineal laceration. Here loss of urine is not

constant, but occasional or frequent. For its treatment the following

methods have been suggested: the injection of paraffin; partial torsion

of the urethra (Gersuny), _i. e._, a partial dissection of the urethra

and revolution upon its own axis, with subsequent suture, by which

incontinence may be overcome, but at the possible risk of sloughing.

Finally, Dudley has proposed the method of advancement of the urethra.

He makes a horseshoe denudation, between the meatus and the clitoris,

down on either side of the urethra, and nearly its entire length.

Its anterior end is then loosened sufficiently so that the meatus

can be drawn forward and secured below the clitoris by two sutures.

The balance of the wound is then closed, the effect of the operation

being to replace and retain the urethra and prevent its sagging. Other

surgical treatment, as for cystocele, laceration, etc., may be added as

needed.

CYSTITIS.

The condition of true _cystitis_ arises invariably either from the

_irritation of a foreign body_ or the _presence of bacteria_; the

former need not necessarily be large, and minute and irritating

crystals are often sufficient to produce at least some of its features.

Sooner or later, however, the germ element enters, and from that time

on cystitis is a bacterial infection. Furthermore this infection is

usually secondary, rarely if ever primary, and may come from without or

within. Thus it may be the consequence of the introduction of unclean

instruments; is a very frequent consequence of gonorrhea, including

all forms of urethritis; or may be the result of local tuberculous

processes or those travelling downward from the kidneys; or, again,

of more general toxic or septic conditions, such as typhoid and other

infectious fevers. Certain conditions predispose, such as the presence

of calculi or the occurrence of traumatism. Again, a bladder weakened

by overdistention or paralysis, as in cases of spinal injury, loses its

natural resisting power and succumbs to infection abnormally easily.

It should be emphasized that the absolutely healthy bladder wall is

resistant to all germ activity, but this resistance is easily lost or

modified in the presence of disease, either close by or distant. A

bladder whose normal shape has been greatly changed by enlargement of

the prostate is again rendered not only unhealthy, but incapable of

acting normally. It becomes, therefore, easily infected, and _cystitis

is a frequent accompaniment of prostatic hypertrophy_.

[Illustration: FIG. 651

Internal appearance of bladder in some cases of inveterate cystitis;

mucosa sacculated by columns of hypertrophied tissue. (Launois.)]

=Symptoms.=--The _cardinal symptoms of cystitis_ are three in number,

_i. e._, _pain_, _frequency of micturition_, and _pyuria_, the latter

being the consequence of changes in the urine, as well as in the

bladder wall, while the pain and the thamuria are expressions of

irritation, especially of the base of the bladder and the posterior

urethra. In fact, all the more violent expressions of cystitis are

found at the lower part of the bladder rather than in its upper

portion. Obviously, then, irritation of adjoining organs is more easily

accounted for, _e. g._, of the urethra, the seminal vesicles, the

prostate, and the lower ends of the ureters.

The _pain_ may be severe, and is especially complained of with each

act of urination. It is referred not only to the region of the bladder

proper, but along the urethra to the end of the penis in the male, and

down the thighs in both sexes. With frequency of urination there is

also distressing urgency, so that once the necessity be felt nothing

can restrain the promptness of the act. In fact so powerful is the

expulsive tendency that the tenesmus affects not only the bladder but

often the rectum, while the feeling or desire to urinate continues

after the bladder has been emptied of its last drop, even for several

minutes, and may cause the patient to sit in agony for some time.

The distress produced in acute cases of cystitis is excessive, and

sedatives and anodynes constitute no small part of the treatment.

The amount of _pus_ contained in the urine will vary with the degree

of acuteness and the stage of the disease. At first it is but slight,

but rapidly increases, until the urine may contain thick mucus and pus

up to one-third or more of its volume. Finally _blood_ may appear, by

whose appearance a serious degree of inflammation is betokened.

Later, at a variable date, the putrefactive element is introduced; and

when the urine begins to smell of ammonia--_i. e._, when _ammoniacal

decomposition_ has once begun--the bladder is thereby the more

irritated and the case made still worse.

No vesical mucosa left suffering from such acute inflammation will

remain unaffected in its tissue elements, but will rapidly become

more or less thickened. In fact the entire bladder wall undergoes a

process of thickening, from hypertrophy of its inner and its muscular

or middle coats, the latter due to extra activity in consequence of

the constant tenesmus. There results in time a marked _eccentric

hypertrophy_, whose result is really a contraction of the bladder

cavity and a distortion of its lining. Under these circumstances, also,

the mucosa becomes _sacculated_, and numerous little pockets, which may

contain decomposing urine, serve to complicate the situation; while,

finally, more or less _incrustation_ or _calculous degeneration_ and

implantation modify the character of the mucous coat. For all these

changes to occur requires time, but their combined effect is such

thickening and contraction of the bladder as to permanently alter it

and lead to a final _concentric_ hypertrophy.

=Tuberculous Cystitis.=--The picture presented by tuberculous disease

of the vesical mucosa is, in the beginning, one of miliary or

disseminated involvement; but later, when ulcerative changes have taken

place, the end results are scarcely different from those rehearsed

above, save that the ulcerative element is more predominant, and

there is great probability of involvement of the ureters or of any of

the adjoining organs. As conditions do not essentially vary, neither

do symptoms, and a diagnosis of tuberculous cystitis often must, in

the early stages, be reached by a process of exclusion, corroborated

perhaps by the cystoscope.

=Postoperative Cystitis.=--A different clinical type of irritation,

or mildly infective cystitis, is known to be a sequel of certain

operations, not alone those upon the pelvis. In the majority of cases

it occurs when catheterization has been required, the first event being

urinary retention, by which the bladder mucosa must be more or less

disturbed. It may be perhaps accounted for by the fact that the urethra

is practically never free from germs, which, in that canal, seem to

be innocent, but which, carried upward into an irritated bladder may

excite serious inflammation. These cases are perhaps more frequent

after pelvic operations for cancer. There seems, however, no doubt

but that repeated catheterization for several days lowers bladder

resistance.

=Treatment.=--When the occurrence of cystitis is imminent prophylactic

or preventive treatment is recommended. This should consist in

administration of large quantities of fluid, with urinary antiseptics,

in lavage of the bladder itself, and in reliable antiseptic precautions

in catheterization. Thus to operate upon a bladder which has long held

seriously infected or decomposed urine, without previously cleansing it

as much as possible, is simply to invite further trouble.

The medicinal treatment of cystitis, on which we mainly rely, consists

in dilution of the urine by large amounts of fluid ingested, in

overcoming hyperacidity by the administration of alkalies, and in

combating putrefactive conditions, so far as possible, by antiseptics

which are eliminated through the kidneys. Balsams have been long held

in great repute; but remedies like urotropin and other synthetic

compounds have taken their place. Of them all, and especially in the

presence of ammoniacal urine, urotropin and the alkaline salts of

benzoic acid seem most reliable. Excessive irritability may be overcome

by local measures, such as frequent hot rectal douches, hot sitz baths;

by quieting irritation of the genitospinal centres by administration,

_e. g._, of cannabis indica, in doses pushed to the physiological

limit; by local anodynes, as by opium suppositories, or in extreme

cases by general anodynes like morphine.

Theoretically a seriously infected bladder should be washed out and

cleansed as any other pus cavity, but when so inflamed the bladder

becomes so intolerant and exquisitely irritable that the mere act of

washing can only with difficulty be borne by the patient. Retention of

a catheter, which might be advisable under most circumstances, may also

be impossible for the same reason. The condition of a patient under

extremes of this kind is pitiable, and resort to general anodynes

unavoidable. Still it is possible with patience and the use of selected

drugs to gradually allay even a most acute cystitis. Confinement in bed

and an almost fluid diet are also necessary features of treatment.

If the introduction of an instrument can be borne it may be possible to

leave in the bladder some soothing solution after it has been washed,

such as a mild cocaine solution containing a little morphine, or olive

oil containing orthoform, or a mild preparation of ichthyol. Even if

these be retained but for a short time they will usually afford relief.

Finally in severe forms of cystitis the _bladder may be opened_ for

the purpose of giving it physiological rest, selecting either the

suprapubic or the median perineal route. The relief thus afforded is

usually gratifying, while drainage may be maintained until the local

treatment has been sufficiently effective to permit either spontaneous

closure of the drainage opening or its repair by suture. This measure

is known as _cystostomy for the relief of cystitis_.

Obviously if cystitis be due to the presence of any foreign body its

treatment becomes necessarily surgical, the same being true of those

forms due to or connected with hypertrophy of the prostate. It is

impossible to accomplish a cure here until the mechanical difficulty is

first overcome.

VESICAL CALCULUS.

In the urinary bladder as well as in the gall-bladder mineral

elements held in solution by the contained fluids are precipitated,

the consequence being the formation of _calculi_ or _stones in the

bladder_, which vary in size from the smallest concretions to those

weighing many ounces, and in number from one to scores, a large

proportion of these representing original concretions passed down

from the kidneys, _i. e._, minute renal calculi. Every calculus has a

nucleus, and in many instances this may be a clot, or clump of cells

encrusted with salts, which have formed within the bladder and not

come down from above. Such foreign bodies will become the nidus for

a calculus, while in vesical calculi are frequently found pieces of

catheter, of straw, chewing-gum, hairpins, and the like, which have

been introduced from without. These stones are constituted mainly

of the ordinary urinary salts, _i. e._, _phosphates_, _urates_, or

_oxalates_, deposited as described above. Much more rarely _cystin_ and

_xanthin_ are found. Instead of urates crystallized _uric acid_ will be

occasionally seen. The oxalates are mostly those of calcium, while the

phosphates are those of calcium, magnesium, or ammonium, more or less

combined. The first requisite for a calculus is a nidus, the second

the deposition of one or more of these salts. Calculi are sometimes

_composite_ in structure, some having a uric or urate nucleus becoming

later encrusted with phosphates. The oxalic calculi are exceedingly

hard and usually rough, being often spoken of as _mulberry_. They

rarely attain large size. The rapidly forming phosphatic calculi are

often so small as to disintegrate or break in the process of removal.

Thus there may be great differences in density of these stones. Their

formation is particularly favored by retention of alkaline urine, as in

many cases of prostatic enlargement.

=Symptoms.=--Discomforts and symptoms produced by bladder stone depend

upon their size, number, roughness, movability, and location. The

larger and rougher stones, which are more or less easily moved inside a

tender and irritable bladder, will cause a large amount of discomfort

and actual pain, while a small calculus, which may be formed within a

pocket or become encysted at some distance from the urethral opening

may remain unnoticed. The indications of calculi are essentially those

of cystitis, _pain_, _frequency of urination_, and _pyuria_, sometimes

with hematuria. The pain is local and referred, especially along the

urethra, to the glans in the male, and is often aggravated by the final

expulsive movements of the bladder at the termination of urination.

Local discomfort is aggravated by active exercise. Reflex pains have

been known in distant parts of the body. The frequency of urination is

increased by exposure to cold or by activity. Pyuria and hematuria do

not differ from those of non-calculous cystitis. A most significant

feature is sudden _stoppage of the urinary stream_, with more or less

pain. Statements to this effect, especially if accompanied by a history

of renal calculi in time past, are most suggestive.

Unless, however, particles of calcareous material have been passed the

positive diagnosis of calculus rests upon its detection by examination,

either with a _stone searcher_ or with the _cystoscope_. The former

is essentially a short-beaked, light sound, which may be more easily

manipulated after introduction within the bladder. In using it the

same precautions are taken as for catheterization or sounding, while

the deep urethra may be made less sensitive by a cocaine solution. The

instrument is introduced exactly as is a sound, and its beak is carried

completely into the bladder. Sometimes even before this has been

accomplished will be noted the rough, grating sensation which indicates

contact with a stone. At other times it is only after considerable

search that a small stone is “touched.” A stone easily found is within

the possibilities of unskilled manipulation, but to accurately examine

a bladder, especially behind a large prostate, is a fine art. For this

purpose the bladder should be partially distended with fluid, the

patient should be in the horizontal position, and the stone searcher so

manipulated that its beak may be made to traverse every portion of the

lower part of the bladder and to come into contact with its wall, for

only in this way can an encysted calculus be discovered. The beak must,

moreover, be rotated so as to be carried down into the pocket behind an

enlarged prostate, as in such pockets many calculi nestle. Some stones

are felt even in introducing a soft catheter; others are discovered

only after such manipulation as the above. Nothing but necrosed bone or

a foreign body can convey to the metal instrument, and through it to

the finger, the peculiar sensation produced by contact with a stone. By

attaching an auscultatory tube to the instrument a characteristic sound

may also be heard.

With the cystoscope in the hands of an expert it is possible to orient

one’s self definitely concerning the size and location of a calculus,

but much information can also be obtained by the use of the ordinary

searcher.

It has occasionally happened that calculi have been discovered by

accident, either during a suprapubic or some other pelvic operation.

=Treatment.=--The presence of vesical calculus being established,

there is but one rational treatment, _i. e._, its _removal_. It

remains, then, only to select the method of operation and to perform

it. Vesical calculi are removed by two general kinds of operations: by

_crushing and evacuation of fragments through the natural passages_,

or by a _cutting operation and extraction entire_. The former is known

as _lithotrity_, or, as now performed in one sitting, _litholapaxy_,

and the other as _lithotomy_, which may be performed either above the

pubis, through the perineum, through the vagina, or through the rectum.

Each method has certain obvious advantages. Thus _in favor of crushing_

there is freedom from an open wound, with its dangers of infection and

of hemorrhage, while it appeals to the sentiment of those patients who

“dread the knife.” One objection to it is that even when performed with

skill assurance cannot be given that the bladder shall be freed from

all calcareous particles, one of which may, by remaining, serve as a

nidus for another calculus. In _favor of the cutting operations_ are

their brevity, _i. e._, the celerity with which they may be performed,

the relief afforded by drainage, which can be carried out through the

lithotomy wound, and which is often indicated in bladders that have

been long tortured by the presence of calculi; while, finally, their

simplicity, at least in most instances, makes lithotomy attractive

to the operator of limited ability. It may be added that certain

calculi, especially of the oxalic type, are so dense and resistant that

even when secured in the grasp of an instrument they can scarcely be

crushed. It may be urged also that septic urine is just as harmful in a

bladder whose mucous membrane has been slightly injured here and there

in the process of crushing as in one which has been more or less opened

by a lithotomy.

Between cutting methods choice varies also according to the taste and

views of various operators, as well as the nature of the case. When the

prostate is large a suprapubic operation was held the simpler for the

removal of calculus, and this earlier teaching is not abandoned. In the

young the urethra is small and the bladder lies high in the pelvis,

and both these conditions favor the suprapubic method. Again it enjoys

repute because there is no danger of injury to the prostatic urethra

or the seminal ducts or vesicles, and because it leaves the genital

apparatus absolutely untouched. It is also free of possibility of harm

to the rectum, which was by no means unknown in the hands of the older

operators who resorted to the perineal route. But the removal of a

large stone by the suprapubic route entails an opening of considerable

size, and it is not unlikely that a large calculus may need to be

fragmented and removed in pieces rather than leave a large opening at a

point where urinary fistulas would likely ensue. It will be seen, then,

that even lithotomy is not always to be performed without crushing of

the calculus.

Of the perineal routes only two are in vogue today, the _median_ and

the _lateral_. The _median_ is resorted to for stones of moderate

dimensions, while the lateral will be required for large calculi. The

vaginal route is often selected in women, although, rather than make an

extensive opening between the bladder and the vagina, it will probably

be easier and better to dilate the urethra, and, through it, crush

a calculus which, in the female, could thus be made more accessible

than in the male. Therefore in the female the suprapubic route or a

litholapaxy is usually adopted. The operation through the rectum has

been long since abandoned.

After a calculus has been removed by crushing a self-retaining catheter

should be inserted, for at least a day or two, and the bladder

washed, while at the same time treatment for the cystitis, which is

still present, should not be discontinued. After opening the bladder

the wound is drained for at least a day or two. Drainage has this

disadvantage, that if long continued it leaves a urinary fistula, often

slow to close, but a metal, glass, or hard or soft rubber tube may be

placed in a median perineal opening, around which should be packed

gauze to check oozing, and left in this condition for two or three

days. Usually within a week after its removal the deep sphincters have

recovered their retentive power, and the patient can retain urine for

some time, while generally within two weeks the entire wound is closed.

In all these cases a sound or bougie should be passed at suitable

intervals for the purpose of preventing stricture formation in the deep

urethra at the site of the operation.

_Litholapaxy_ is performed by first crushing the stone between the

beaks of an instrument known as the _lithotrite_, which is constructed

in various forms, yet all conforming to one type, which is introduced

into the bladder through the urethra, after which its blades are

separated and manipulated until the stone is felt to be entangled

or secured between them. By a device at the handle the blades are

then locked, and screw power exerted, also from the handle, by which

the blades are forced together and the stone between them more or

less broken (Figs. 652 and 653). By repetition of this process each

fragment is seized separately and crushed until the bladder contains

more or less debris resulting from the manipulation. The lithotrite

is then removed and a _washing tube_ or catheter of large dimension

inserted, and connected with a so-called _washing bottle_, which is

compressible and permits a stream of water to be violently thrown into

the bladder, thus stirring up the fragments and particles, and which is

an instant later withdrawn by suction in such a way as to carry them

with it. Escaping into the washing bottle they drop by gravity into a

glass receptacle at its base, where they become at once visible. This

process is repeated until everything has been washed out of the bladder

which will come. The lithotrite is then substituted and the maneuver

repeated, and as many times as may seem desirable. In this way calculi,

especially soft ones of large size, may be disintegrated and removed

in small fragments. The final test of success is failure to aspirate

any more particles or to discover them with the cystoscope (Fig. 654).

The time consumed in the operation will depend on the operator’s skill

and the size or hardness of the stone. It is frequently performed

under local anesthesia, the bladder being injected with a weak cocaine

solution, or under spinal anesthesia.

_Lithotomy_, by either of the above methods, is performed by utilizing

a grooved sound known as a _staff_, which is first inserted into the

bladder, and serves not merely the purpose of a grooved director, but

to indicate the course of the urethra.

For the _suprapubic operation_ the staff is passed deeply, and its

handle depressed between the thighs, so that the end of the instrument

rises behind the pubis and carries the bladder up toward the surface.

A median incision above the pubis permits access between the recti

muscles to the prevesical space (space of Retzius), which is more

or less filled with fatty and connective tissue. If the bladder has

been previously distended with fluid and elevated on the point of

the staff, there is but little danger of wounding the peritoneum,

although its reflection may be sought and carried out of harm’s way.

It is a convenience to pass a silk suture with a stout, full-curved

needle through the bladder wall after it has been exposed, on either

side of the point of the staff which elevates it, and to pass this

through in such a way as to have thus a double loop, or two retractors,

by which it may be more conveniently manipulated after it has been

opened and would otherwise collapse. The bladder should be opened upon

the point of the staff, whose groove may then serve as a guide in

still further nicking or incising it, the silk sutures on each side

preventing it from collapsing as it otherwise would after the gush of

escaping fluid. The surgeon should now endeavor so far as possible

to dilate rather than to merely cut this opening, and thus give it a

size sufficient to permit the introduction of the finger, by which

intravesical exploration and orientation are effected. Calculi having

been identified and located, suitable forceps are then introduced, and

with them the stone or stones seized and withdrawn through the opening,

which may be stretched still farther for the purpose unless their size

make it advisable to crush them and remove them in fragments.

[Illustration: FIG. 652

Method of seizing the stone behind the prostate.]

[Illustration: FIG. 653

Ordinary position in seizing the stone.]

[Illustration: FIG. 654

Bigelow’s lithotrites, catheters, and evacuator.]

This is suprapubic cystotomy or epicystostomy, according to the purpose

for which it is intended. It serves not only for removal of calculi

but for extirpation of tumors, or enlarged prostates, and perhaps for

permanent drainage. By the silk loops at first introduced the bladder

wall may be attached to the abdominal wound, while other stitches may

be added to any desired extent. In most instances it is desirable to

reduce the opening, for which purpose buried and superficial sutures

may be used. As leakage, however, may produce infection it is customary

either to provide for drainage by insertion of a catheter through the

urethra, or by the implacement of a small tube, whose lower extremity

shall reach the base of the bladder and serve for drainage, which

latter may be made more effective by siphonage.

PERINEAL LITHOTOMY.

The principles and practice of modern surgery · 第 52 / 57 章