CHAPTER XI.

Transcriber’s Note

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EMINENT DOCTORS.

Ballantyne Press

BALLANTYNE, HANSON AND CO.

EDINBURGH AND LONDON

EMINENT DOCTORS:

Their Lives and their Work.

BY

G. T. BETTANY, M.A. (CAMB.), B.SC. (LOND.), F.L.S.

AUTHOR OF “FIRST LESSONS IN PRACTICAL BOTANY,”

“ELEMENTARY PHYSIOLOGY,” ETC.

AND LECTURER ON BOTANY IN GUY’S HOSPITAL MEDICAL SCHOOL.

“There is to me an inexpressible charm in the lives of the good,

brave, learned men, whose only objects have been, and are, to

alleviate pain and to save life.”

—G. A. SALA.

_IN TWO VOLUMES._

VOL. II.

[Illustration: Bookmaker’s Mark]

LONDON:

JOHN HOGG, PATERNOSTER ROW.

[_All rights reserved._]

CONTENTS OF VOL. II.

CHAP. PAGE

XI. ADDISON, BRIGHT, AND THE DISEASES WHICH BEAR

THEIR NAMES 1

XII. LISTON, SYME, LIZARS, AND THE NEWER SURGERY 24

XIII. BAILLIE, HALFORD, CHAMBERS, AND HOLLAND, THE

FASHIONABLE AND COURTLY PHYSICIANS 51

XIV. SIR WILLIAM FERGUSSON AND CONSERVATIVE SURGERY 71

XV. SIR JAMES SIMPSON AND ANÆSTHETICS 83

XVI. SIR SPENCER WELLS AND OVARIOTOMY 105

XVII. SIR WILLIAM JENNER, BUDD, MURCHISON, AND

TYPHOID FEVER 118

XVIII. SIR JOSEPH LISTER AND ANTISEPTIC SURGERY 135

XIX. SIR THOMAS WATSON, SIR DOMINIC CORRIGAN, SIR

WILLIAM GULL, AND CLINICAL MEDICINE 148

XX. SIR JAMES PAGET AND SURGICAL PATHOLOGY 167

XXI. WILLIAMS, STOKES, AND DISEASES OF THE CHEST 178

XXII. SIR HENRY THOMPSON AND CREMATION 194

XXIII. GRAVES, HUGHES BENNETT, AND CLINICAL TEACHING 201

XXIV. CONOLLY, MAUDSLEY, AND MENTAL DISEASES 217

XXV. EMINENT SPECIALISTS: SIR ERASMUS WILSON AND

SKIN DISEASES; MORELL MACKENZIE AND THROAT

DISEASES; COBBOLD AND INTERNAL PARASITES 239

XXVI. EMINENT SPECIALISTS—_continued_: SIR W. BOWMAN,

BRUDENELL CARTER, AND EYE DISEASES; TOYNBEE,

HINTON, AND EAR DISEASES 260

XXVII. SIR R. CHRISTISON, SWAINE TAYLOR, AND POISON

DETECTION 285

XXVIII. PARKES, GUY, SIMON, AND PUBLIC HEALTH 295

INDEX 307

EMINENT DOCTORS.

CHAPTER XI.

_ADDISON, BRIGHT, AND THE DISEASES WHICH BEAR THEIR NAMES._

Operative dexterity, as was natural, arrived more quickly at

perfection than did medical treatment. In fact, no one will pretend

that medicine has yet travelled far, in comparison with its future

achievements, when physiology, pathology, and therapeutics shall

have become more complete. THOMAS ADDISON is a specimen of the

physicians of genius who have adorned this century. He is known as

the discoverer of a disease which bears his name; but his true fame

rests upon his practical talent in diagnosing disease.

Dr. Lonsdale, in his volume of “Worthies of Cumberland,” issued in

1873, shows that Addison sprang from the ranks of the yeomanry of

Cumberland, and that his forefathers resided during the Commonwealth

at “The Banks,” in the parish of Lanercost. Thomas Addison, born

in 1636, and Mary his wife, have left their initials carved on an

old oaken settle still preserved at The Banks, inscribed with

the injunction, “When God doth thee in store, remember thou the

poor.” One of his descendants was a Samuel Addison, who became a

doctor of medicine, but died at the age of thirty-four. Thomas

Addison, a nephew of his, was born in April 1793, at Longbenton,

near Newcastle-on-Tyne, where his father was in business, though he

retained his farm at The Banks, where his wife lived for the most

part. Young Addison clung greatly to the ancestral home, and many

years afterwards assembled his wedding guests there. It is on the

very site where the Romans encamped during the building of the wall

to the Solway Firth; it overlooks the medieval Priory of Lanercost;

near by is Naworth, the old Border castle of “Belted Will Howard.”

Thomas Addison was educated at the Newcastle grammar-school under

the Rev. E. Moises, and there became a masterly Latin scholar, so

that he afterwards took his lecture notes in Latin at Edinburgh.

He went direct from school to Edinburgh University, declining to

enter as a pupil with an Edinburgh doctor, as his father desired. He

was no ordinary student. Independent in thought and action, he was

soon recognised by the Royal Medical Society, and made one of its

presidents in 1814, an honour which Marshall Hall, and Richard Bright

his subsequent colleague, also attained about that time. A striking

fact it is that three of the first names of great English physicians

of this century should be Edinburgh students, and Presidents of the

same Medical Society there. But as yet the London medical schools

were only in embryo.

Addison took his M.D. degree in 1815, and afterwards, it is believed,

visited the Continental schools; but of this there is no certain

evidence. He soon settled in London, in Skinner Street, Snow Hill,

in one of the so-called haunted houses. He knew but one man, an old

fellow-student, in London. Yet he received nearly sixty guineas

in his first year of practice, a very considerable success. He

became House Surgeon to the Lock Hospital; then Physician to the

General Dispensary, where he studied skin diseases with Bateman.

This appointment he held for eight years, and it was of essential

service to him. He manifested a keen eye for generic distinctions and

individual varieties, and might probably have succeeded to Bateman’s

position in regard to skin diseases. But he was not to be made into

a specialist. As Dr. Lonsdale says, “with Addison the investigation

of any disease meant the full exercise of his abilities till he had

mastered it, and having done this, he could not rest till he broke

up fresh ground for tillage.” He dreaded becoming a specialist; it

savoured of quackery. He always held that the true physician must

understand surgery well; and that the good surgeon must know the

principles of medicine.

In 1819 or 1820 commenced Addison’s association with Guy’s. He early

attracted the attention of the energetic and discerning treasurer,

Mr. Harrison, then the beneficent despot of Guy’s, and was by

him appointed Assistant-Physician in 1824. This was a victory for

unconventional procedure, for it had always been the custom to

appoint men at Guy’s who had been original pupils, and not to receive

men who were already qualified and in practice into the charmed

circle. It was soon evident that a great practical physician had

joined the hospital staff, and he was further recognised in 1827 by

receiving the lectureship of Materia Medica. Here his attractive

powers were made evident by the large classes he drew around him,

at a period when medical students entered for individual courses of

lectures, and did not as a rule take the whole of their instruction

at one school. He must have received between £700 and £800 from these

lectures in some years. Men felt that he was the man to sustain and

increase the fame of Guy’s.

In 1829 Dr. Addison published, in conjunction with John Morgan,

Surgeon to Guy’s, an essay on “The Operation of Poisonous Agents

on the Living Body.” Strange to say, this was the first serious

investigation in England into the phenomena of general poisoning.

The authors believed that a direct influence on the nerve filaments

distributed to the blood-vessels accounts for the rapid effects of

some of them. In 1830, Addison published a pamphlet on some disorders

of females, vigorously combating some received notions, and objecting

to the system of depletion. In concluding a lengthy lecture to his

class on this subject, he showed the sentiments which animated him

by the following remarks: “Gentlemen, if you require an apology for

detaining you so long, I find ample material for that apology in

the lively interest in which we must all feel in the comfort and

happiness of the other sex, doomed as they are, both by the decrees

of Providence and by human institutions, to drink deep of the bitter

cup of suffering. Whatever may be her lot in this world, we, as men,

must at least acknowledge that, whilst Infinite Power gave us being,

Infinite Mercy gave us women.”

In 1837 Addison was elected full Physician to the Hospital, and was

appointed joint-lecturer with Dr. Bright on Medicine. About this time

he commenced with his colleague the “Elements of the Practice of

Medicine,” of which the first volume only appeared, chiefly written

by Addison. It was most highly valued, but neither author could be

induced to complete it. Valuable monographs in number came from his

rich experience: two on Pneumonia in 1837 and 1843; Observations on

the Anatomy of the Lungs in 1840; the Pathology of Phthisis, 1845, in

which he laid down the principle that inflammation constitutes the

first instrument of destruction in every form of phthisis. This early

advocacy of a doctrine which has thrown much light on this disease

was strongly opposed by the physicians of his day, and stamped

Addison as a powerful innovator. He was much impressed by Laennec’s

views, and acquired very great power of diagnosing from auscultation

of the chest. Yet, candid ever in confessing ignorance, he read a

paper before Guy’s Physical Society in 1846, “On the Difficulties and

Fallacies attending Physical Diagnosis of Diseases of the Chest.”

Among other subjects, he dealt with Diseases of the Liver, Affections

of the Skin, Disorders of the Brain connected with Diseased Kidneys,

and “the Influence of Electricity as a Remedy in certain Convulsive

and Spasmodic Diseases,” in every case bringing together facts

hitherto disconnected, and contributing markedly to advance medicine

as a science.

The achievement of Dr. Addison, however, which has attracted most

general notice, is his discovery of a disease of the supra-renal

capsules, the small organs adjacent to the kidneys, whose function

has not yet been satisfactorily ascertained. We are told that in

one case, which had baffled all investigation, Addison was called

in, and after careful enquiry, stated positively that the patient

suffered from a disease of these organs, which would before long

prove fatal. This opinion was received with polite incredulity,

but it was justified by the result, and the supra-renal capsules

were the only organs that were found diseased. This extraordinary

diagnosis was soon noised abroad, and on the Continent brought

Addison more honour than in England. Trousseau in France was

cordially supported in naming it “la Maladie d’Addison” (Addison’s

disease), a name which it will long retain. But the disease was not

discovered in this apparently sudden and striking manner, but was

the result of observations carried on for many years, in which

his powers of deduction from a few cases and imperfect data were

most strikingly evidenced. The disease occurs rarely, and very few

hints or materials for comparison were available. A form of wasting

disease without any apparent organic injury had been again and again

observed—bloodlessness, extreme prostration, and various shades of

alteration in the colour of the skin, being prominent symptoms. A

certain bronzing of the integument was, and still is, an inexplicable

concomitant, and no light was thrown upon it till Addison, carefully

examining the organs of a deceased patient, when no other disease

could be detected, discovered signs of malady in the supra-renal

capsules. He identified the disease, and though he did not absolutely

mark it out from all others, he gave a very perfect account of the

symptoms in the cases which he had met with, and showed that no other

disease could be connected with them—indeed no other disease of these

capsules has been discovered.

As a teacher Addison was impressive and popular. His interest in

his class was genuine and unfeigned; he was eager to draw out the

talents of his students. Among his pupils were Dr. Golding Bird,

too early called from his brilliant career, Sir William Gull, Dr.

Wilks, and many others of note. His clinical teaching in the wards

was especially superior. He could most vividly illustrate on the

patient, and most clearly define and demonstrate his disease. He

disliked anything like interference with his methods by others,

and sometimes showed it somewhat brusquely. Once when he had been

away from his wards for a few days, a colleague had seen reason to

change his treatment of a case of pleurisy. On Addison’s return,

he at once inquired the reason, and was told that the physician in

charge believed the case to be one of pneumonia and solidification

of the lung. “Ah indeed!” said Addison, “give me a trocar;” and he

immediately plunged the little instrument into the chest, and drew

off a few ounces of fluid, proving the accuracy of his own diagnosis.

He wasted no time in considering or discussing probabilities; he was

certain, and he proved that he was right.

Dr. Wilks’ view of Addison’s character, in the collected edition

of his works published by the New Sydenham Society, 1868, is so

pertinent that it must find a place in any adequate account of

Addison:—

“His strong, positive, and perpetual insistence upon the term

‘practical,’ in reference to disease, constitutes, indeed, the

key to Addison’s character and professional career. He was always

ready to discuss newly-started theories, but he never for a moment

allowed them to interfere with the results of his matured experience.

Possessing unusually vigorous perceptive powers, being shrewd and

sagacious beyond the average of men, the patient before him was

scanned with a penetrating glance, from which few diseases could

escape detection. He never reasoned from a half-discovered fact, but

would remain at the bedside, with a dogged determination to track

out the disease to its very source, for a period which constantly

wearied his class and his attendant friends. So severely did he tax

his mind with the minutest details bearing upon the exact exposition

of a case, that he has been known to startle the ‘sister’ of the

ward in the middle of the night by his presence; after going to bed

with the case present to his mind, some point of what he considered

important detail in reference to it occurred to him, and he could

not rest till he had cleared it up. He has also been known, after

seeing a patient within the radius of eight or ten miles, to have

remembered on his near approach to London, thinking over the case

on his way, that he had omitted some seemingly important inquiry,

and to have posted back some miles for the purpose of satisfying

his mind on the doubt which had occurred to it. If at last he could

lay his finger on the disease, his victory was attained, and his

painstaking satisfactorily rewarded. For with him accurate diagnosis

was the great, and too often the ultimate object of an industry of

search, a correlation of facts deduced from scientific observation,

and a concentration of thought rarely combined in the individual

physician. To those who knew him best, his power of searching into

the complex framework of the body, and dragging the hidden malady to

light, appeared unrivalled; but we fear that the one great object

being accomplished, the same energetic power was not devoted to

its alleviation or cure. Without accusing Addison of a meditated

neglect of therapeutics, we fancy that we can trace the dallying with

remedies which has been the characteristic of more recent times.

‘I have worked out the disease; if it be remediable, nature, with

fair play, will remedy it. I do not clearly see my way to the direct

agency of special medicaments, but I must prescribe something for

the patient, at least, to satisfy his or her friends,’ seems to have

been a part of the habit of mind which can deal satisfactorily only

with the observable and proven, and shrinks from the uncertain and

questionable.”

Addison did not seek to push himself into notoriety. Indeed he seems

to have studiously kept himself in the background as regards public

life. He took little pains to seek publication of his researches in

the medical journals, and for the most part his excellent papers

appear in Guy’s Hospital Reports. Thus his practice was not equal

to his great merits, though he died worth £60,000. In professional

intercourse he appeared blunt, and even at times rude, giving

the idea of hauteur and assumption of superiority. The general

practitioner was liable to find him unapproachable, and to conceive

of him as a man of large self-esteem. Yet underneath this outward

semblance lay a most acute nervousness of temperament. This powerful,

well-built, energetic, emphatic man concealed a physical nervousness

and susceptibility which most deeply affected him in circumstances

of trial. He often said, “I never rose to address the Guy’s Junior

Physical Society without feeling nervous;” and yet at the same

time he appeared to his audience to be speaking in a tone akin

even to bluster. His apparent discourtesy was as far as possible

from representing his real sentiments. “Viewed in its professional

aspect,” says Dr. Wilks, “no character on record has presented in

a higher degree the sterling hard qualities of true professional

honesty. We have never heard a single instance in which a word of

disparagement of a professional brother escaped him. He would always

strenuously, and with all his natural vigour, maintain what he

believed to be the truth, but never for the purpose of underrating

the opinions of others. His whole bearing in the profession was to

the last degree honourable, and anything like jealousy or ill-will

against another professional man never entered his mind.”

The chief honour outside his school that fell to Addison was the

Presidency of the Royal Medical and Chirurgical Society. But court

favour did not shine on him, though none would have more worthily

received it. On the Continent, as we have before said, Addison was

treated with the utmost distinction. When he visited Paris, Nélaton,

Trousseau and the élite of the profession entertained him at a public

dinner, and gave him the warmest reception. Addison made an eloquent

speech in excellent French. He was a zealous Tory, not approving

of Disraeli’s modernised policy, but equally removed from Eldon’s

tyrannical rule.

Guy’s Museum of Pathology, adorned by an admirable bust of him

by Joseph Towne, bears large testimony to Addison’s energy and

discernment. He added to it very largely, and his early study of

skin diseases led him to suggest and superintend in execution a plan

for illustrating skin diseases by wax models, and carefully coloured

drawings from life—a process afterwards extended widely through the

range of pathology.

“Every feature of Addison’s face,” says Dr. Lonsdale, “was well

defined, and comported well with his finely-proportioned massive

head. He had dark hair, large eyebrows, and eyes of deep hazel

colour; his nose was pronounced, his lips full and voluble, and

rather special in action, and his chin firm and broad; and his

general physiognomy was stamped with vigour and unmistakable

character throughout. He had a deep penetrating eye, that became full

of life and light when engaged in debate. Of commanding presence

and firm significant step, he possessed a keen penetrativeness,

indeed a special discernment that never failed him in private life,

and but rarely at the bedside of the sick. He stood before you the

impersonation of power and dignity and independence.” Some persons

who knew him well believed that he would have had equal success

at the bar, in the senate, in the navy or the Church. Whatever he

attempted, he would have mastered, and would have carried out,

undisturbed by opposition, undeviating in principle.

Dr. Addison did not marry till he was some years over fifty. His wife

was the widow of W. W. Hanxwell, Esq. The wedding, in September

1847, took place in Lanercost Church, and was attended by an unusual

incident. Just before the ceremony, and unknown to the party, a storm

had blown part of the roof of the church on to the altar table. When

he saw the wreckage, Addison exclaimed to his biographer, nervously

clutching his arm, “Good God, Lonsdale! is this not ominous?” But

his friend, suggesting that any part of the building would do for

the ceremony, and the bride smilingly showing no diminution of

cheerfulness, reassured the doctor, and all went off well. Mrs.

Addison, who had two children by her first husband, but none by

the second, survived Dr. Addison twelve years. She is described as

extremely amiable, and an excellent wife.

In the spring of 1860 Addison was compelled to retire from his

hospital duties by a threatening of brain-disease. He settled at

Brighton; but his disease progressed, and ended in his death on

29th June 1860. He was buried at Lanercost on the 5th of July. A

marble tablet in the chapel of Guy’s Hospital records that he won

the admiration and the confidence of the students of the Hospital

by his profound knowledge and earnest eloquence: and that he was

beloved by the patients for his unwearied attention and kindness to

them. One of the medical wards in the new buildings of Guy’s is named

after him “Addison Ward.” It is worthy of note that Addison, like

John Bell, was a musician, and ready at learning a new instrument.

Being slightly deaf in one ear, he was correspondingly acute with the

other. This ear he used with surpassing skill in auscultation of the

heart and lungs.

* * * * *

In the preface to an edition of Dr. Bright’s “Clinical Memoirs on

Abdominal Tumours,” published by the Sydenham Society in 1861, Dr.

Barlow well remarks, “There has been no English physician—perhaps it

may be said none of any country—since the time of Harvey, who has

effected, not only so great an advance in the knowledge of particular

diseases, but also so great a revolution in our habits of thought,

and methods of investigating morbid phenomena and tracing the

etiology of disease, as has the late Dr. Richard Bright. To those who

have received the knowledge of the connections of dropsy, albuminous

urine, and disease of the kidney, among the first rudiments of

medicine, the facts which establish that connection may appear

so simple and easily ascertained, that the amount of labour, the

accuracy of the observation and the rigid adherence to the inductive

method which characterised the whole of Bright’s researches, may

hardly have been suspected, still less adequately appreciated.”

RICHARD BRIGHT was born at Bristol in September 1789, his father

being a member of the wealthy banking firm of Ames, Bright, & Cave,

and his elder brother subsequently representing Bristol in three

parliaments. His early education was conducted by Dr. Estlin, and

later by Dr. Carpenter, both names of note in Bristol. In 1808 he

entered at Edinburgh University, at first attending Dugald Stewart,

Playfair, and Leslie, in whose mathematical class he gained a prize

in 1809, commencing the study of medicine under Monro tertius, Hope,

and Duncan.

In 1810 Dr. Bright, with Dr. (afterwards Sir Henry) Holland,

accompanied Sir George Mackenzie in his journey through Iceland, and

contributed notes on botany and zoology, as well as other portions,

to “Mackenzie’s Travels in Iceland” (Edinburgh, 1811). Mackenzie

acknowledges Bright’s cheerful and ready exertion and undeviating

good-humour in the many cross accidents that befel the party. Several

times the two medical friends were in imminent danger, and we cannot

but be thankful that these lights of medicine were spared to do their

life-work.

Returning from Iceland, Bright’s clinical hospital work was commenced

at Guy’s Hospital, London, where he lived in the house of a resident

officer for two years, a foretaste of the forty years’ residence

which he practically made within its walls. Astley Cooper was then in

his best form, and young Bright was at once attracted to pathology

and _post mortem_ observation. At this early date he made a drawing

of a granular kidney, one of the morbid conditions which he was

afterwards to do so much to elucidate. In 1812-13 Bright was again

a student at Edinburgh, where Gregory was still in full vigour: and

he graduated on the 13th September 1813, producing a thesis on

Contagious Erysipelas. With the idea of graduating at Cambridge,

he entered at Peterhouse, where his brother was a lay-fellow, but

he only resided two terms, finding his studies impeded by college

discipline. In 1814 Bright was one of the crowd of English voyagers

upon the Continent, and made himself conversant with French and

German, attending professional lectures especially at Berlin and

Vienna. In the spring of 1815 he travelled considerably in Hungary,

and the result of his observations, for he was emphatically an

observer, was given to the world in his large quarto volume of

“Travels from Vienna through Lower Hungary, with Remarks on the State

of Vienna during the Congress of 1814,” published at Edinburgh,

1818. This was a most valuable contribution on the social condition,

statistics, and natural history of that country, then so little known

in England. In all this it is evident how much Dr. Bright’s career

was facilitated by the comfortable circumstances in which he was

placed pecuniarily: not that money gave him his talent, but that it

prevented him from suffering from the obstacles and disadvantages

which have attended the career of so many physicians.

Meanwhile, Dr. Bright, in the winter of 1814, had been studying

cutaneous diseases under Dr. Bateman at the Dispensary. On his return

home through Belgium, about a fortnight after Waterloo, he saw many

interesting cases of disease among the sick and wounded from the late

contending armies. In December 1816 he was admitted a Licentiate

of the London College of Physicians, and was soon after elected

assistant-physician to the London Fever Hospital, paying the frequent

price of a severe attack of fever, which almost cost him his life.

In the summer and autumn of 1818 he again visited the Continent,

spending a considerable time in Germany and Italy, and returning

through Switzerland and France.

From 1820 we may date Bright’s full entry upon his professional

career; for he now took a house in Bloomsbury Square for private

practice. His election the same year to the assistant-physiciancy to

Guy’s Hospital led him to give up the Fever Hospital and concentrate

his attention on the work at Guy’s. He became speedily noted for his

diligent attendance in the wards, and for tracing the causes of his

patients’ symptoms in the _post mortem_ room when they unhappily

arrived there. For many years he spent six hours a day in his beloved

scene of investigation; and long afterwards, when private practice

absorbed more of his time, he longingly looked back upon the past

years of cheerful research and successful toil. His progress, well

prepared for, was now rapid. In 1821 he was elected F.R.S.; in 1822

he began to lecture on Botany and Materia Medica; and in 1824 he

lectured on Medicine, in conjunction at first with Dr. Cholmeley,

later taking the whole course alone. Some years afterwards Dr.

Addison became associated in this lectureship, and the two famous

men for many years upheld and raised the fame of Guy’s by their

copartnership.

Bright was not a theorist, was devoid of special doctrines and

“views,” but as Dr. Wilks[1] well puts it, “he could see, and we

are struck with astonishment at his powers of observation, as he

photographed pictures of disease for the study of posterity.” From

this Dr. Wilks infers that he did not thoroughly perceive the value

of his own work, and that he attached no more importance to diseases

of the kidney than to those of the liver and brain, which he also

described. Dr. Wilks even regards many observations of Bright as

more novel and original when they were published than those relating

to the kidney, but the latter were of more value, and their greater

significance was at once recognised. It should be distinctly

understood that Bright was not simply a specialist in kidney disease,

but a clinical physician of rare excellence, who followed his cases

into the _post mortem_ room, and carefully observed not only the

changes which had taken place in the organ whose disease had caused

death, but also the state of all the other organs of the body. He was

one of the first, if not the first, to describe acute yellow atrophy

of the liver, pigmentation of the brain in melanæmia (or pigmented

blood) due to miasma, condensation of the lung in whooping-cough,

unilateral convulsion without loss of consciousness in local brain

diseases, the bruit of the heart in chorea, the small echinococci on

the interior of hydatid cysts, &c.

It is strange indeed that dropsy should have existed so long and

its cause have been undiscovered; and that renal disease, as we now

understand it, should have been almost unknown. For more than a

century before Bright’s work was published the occurrence of albumen

in the urine of dropsical persons had been known; and cases had been

noted where convulsions and blood-poisoning had occurred when the

kidneys had been found small and granular after death. Dr. Blackhall

had written a treatise on dropsy in 1813; but though he found the

urine albuminous, he rarely went to the _post mortem_ room and

examined the kidneys, which indeed might often at that time remain

untouched. But until Bright’s first quarto volume of “Reports of

Medical Cases,” 1827, appeared, renal disease had not been recognised

as an important malady; he was at once hailed as a discoverer, and

the malady called after his name. He first showed how to recognise

a common form of disease, and systematised what was known about it,

and he further demonstrated that there were three or four varieties

of it, a view which subsequent investigation has most fully confirmed

and developed in most important directions. He proved that not only

was there a continual withdrawal from the blood of most important

albuminous constituents, but that this was frequently attended with

a failure to remove by the kidneys that natural product of waste,

namely urea, which remaining in the blood in excess became poisonous,

and often produced convulsions and inflammations at a distance

from the kidneys. This latter view of the consequences of retained

secretion was not adopted without considerable opposition, but fuller

inquiry only made its truth more evident. And the adoption of a new

truth had its reflex effects in other departments of investigation.

Diseases of other excretory organs might possibly be caused in

the same way; and so the effects of diseased liver in causing

retention of the bile and its circulation in the tissues became anew

illuminated; and bile-poisoning and blood-poisoning were placed on a

new footing.

Although a large amount of time for many years was given to the

investigation of renal cases, many other departments of research

were the objects of Dr. Bright’s careful attention. We have already

referred to some of these. Perhaps one series of phenomena that he

was as much interested in as any was the various tumours of the

abdomen, and the means of diagnosing between them. He published

in Guy’s Hospital Reports an extended set of monographs on these

subjects, which have been published in a collected form by the

New Sydenham Society. They are chiefly clinical, illustrated by

well-grouped cases, observed and recorded with great care and

accuracy, and abounding in important suggestions as to diagnosis and

function.

The second volume of “Reports of Medical Cases” appeared, in two

parts, in 1831, and contained principally narrations of cases of

cerebral and spinal diseases, including paralysis, epilepsy,

tetanus, hydrophobia, and hysteria, with observations on their nature

and pathology. The many coloured plates in both volumes are of great

excellence and authority, being executed under Dr. Bright’s own

superintendence. He was afterwards associated with Dr. Addison in

the production of the first volume of the “Elements of the Practice

of Medicine.” The first volume of Guy’s Hospital Reports, published

in 1836, contains no fewer than eight papers from Bright’s own pen.

In 1832 Dr. Bright was elected a Fellow of the Royal College of

Physicians, and in 1833 gave the Gulstonian lectures at the College,

on the Functions of the Abdominal Viscera, with observations on the

diagnostic marks of the diseases to which the viscera are subject.

In 1836 he was censor, and in 1837 gave the Lumleian lectures on

Disorders of the Brain.

In his early years Dr. Bright’s practice was not very extensive. He

was disinclined to use any adventitious aids to popular reputation,

and was content to pursue his tireless investigations. His

publications on renal disease gradually attracted general attention,

and the profession found him a most reliable and valuable consultant,

so that in his later years he commanded a first-class practice. A

few years before his death he resigned his post at Guy’s Hospital,

and was made Honorary Consulting Physician. He died on the 11th

December 1858, from the consequences of extensive and long-standing

ossification of the aortic valves of the heart, the exit for the

blood being reduced to a mere chink. He had long suffered very

considerably, but was never thoroughly examined in life. However,

he believed considerably in the value of medicine, and took large

quantities of some kinds. He was buried at Kensal Green.

Bright is described as having had “a remarkably even temper and

cheerful disposition: he was most considerate towards the failings

of others, but severe in the discipline of his own mind. He was

sincerely religious, both in doctrine and practice, and of so pure

a mind that he never was heard to utter a sentiment or to relate an

anecdote that was not fit to be heard by the merest child or the

most refined female. He was an affectionate husband and an excellent

father, not only taking the most lively interest in the welfare of

his children, and in their pursuits, but never so happy as when he

had them around him; so that half the pleasure of the long vacation

was lost, unless he had as many members of his family as possible

for his companions.” He married, first, the third daughter of Dr.

Babington, senior; and secondly a sister of Sir William Follett, by

whom he left surviving three sons, one being Dr. Bright of Cannes,

and another the Rev. James Franck Bright, the well-known historian,

and Master of University College, Oxford.

It is said of Bright that he was perhaps better known abroad than

any other British physician of his time. The confidence reposed

in him by his professional brethren was dependent largely upon the

minute attention he bestowed upon every case. He always took careful

notes, and often made drawings, being a good draughtsman and rather a

connoisseur in etchings and engravings.

FOOTNOTES:

[1] Historical Notes on Bright’s Disease, Addison’s Disease, and

Hodgkin’s Disease, in Guy’s Hospital Reports, 3d series, vol. xxii.

Eminent doctors: Their lives and their work; Vol. 2 of 2 · 第 1 / 19 章