CHAPTER VI.

SWEATING SICKNESSES.

Ἔστι γὰρ τὸ πάθος λύσις τῶν δεσμῶν τῆς εἰς ζωὴν δυνάμιος.

ARETÆUS.

SECT. 1.—THE CARDIAC DISEASE OF THE ANCIENTS.

(MORBUS CARDIACUS.)

Thus by the autumn of 1551, the Sweating Sickness had vanished from

the earth: it has never since appeared as it did then and at earlier

periods; and it is not to be supposed, that it will ever again

break forth as a great epidemic in the same form, and limited to a

four-and-twenty hours’ course; for it is manifest, that the mode of

living of the people had a great share in its origin; and this will

never again be the same as in those days. Yet nature is not wanting

in similar phenomena, which have appeared in ancient and modern

times; and if we take into the account the great frequency of cognate

rheumatic maladies, it is possible that isolated cases may have

sometimes occurred, in which repletion of impure fluids, and violently

inflammatory treatment have augmented a rheumatic fever, even to the

destruction of nervous vitality, by means of profuse perspiration—only,

perhaps, that they ran a longer course, (which does not constitute

an essential difference,) and under totally different names, whereby

attention is misled. Of all the diseases that have ever appeared

which can in any way be compared to the English Sweating Sickness, we

have principally three to look back upon—the _cardiac disease_ of the

ancients, the _Picardy sweat_, and the _sweating fever of Rötingen_.

The first was, for reasons which have been already mentioned[812],

almost unknown to the learned of the sixteenth century; and it is

matter of surprise, that Kaye himself, who had chosen for his favourite

the best Roman physician, we mean Celsus, could have so entirely

overlooked his by no means unimportant statements respecting this

disease. _Houlier_ is the only author who ventures a comparison of the

English Sweating Sickness with the ancient cardiac disease; his few,

and almost lost words[813], remained however unheeded; nor are the

differences between the two diseases small: but to return.

The disease of which we are speaking appeared for a period of 500

years, (from 300 B.C. to 200 after Christ,) and was a common, almost

every day occurrence, which is often mentioned even by non-medical

writers. It was exceedingly dangerous, and even esteemed fatal; and

as it was far above the reach of Greek physiology, there were not

wanting extraordinary opinions respecting its nature, and bold and

singular modes of treatment, to which those who were attacked were

subjected. The name _Cardiac disease_ (morbus cardiacus, νόσος καρδιακὴ

and probably also νόσος καρδίτις,) was not bestowed by medical men,

but by the people; who, in the fourth century before Christ, for the

name is as ancient as that period, could not know that the learned

would dispute on that subject. Some affirmed, and among them men of

great authority, such as _Erasistratus_, _Asclepiades_, and _Aretæus_,

that the people were in the right so to call the disease; that the

heart was actually the part affected, and that their knowledge of the

heart’s functions was by no means small[814]. Others, on the contrary,

would only acknowledge in that name an expression indicative, not

of the particular seat of the disease, but only of its importance,

inasmuch as the heart is well adapted, as the centre and source of

life, to indicate this[815]. Others again, who attempted more refined

conjectures, wished to represent the pericardium as the seat of the

malady, because darting pains were sometimes felt[816] in the region

of the heart, or the diaphragm, or the lungs, or even the liver. The

opinions were numerous; the actual knowledge was small[817].

The cardiac disease began with rigors and a numbness in the

limbs[818], and sometimes even throughout the whole body. The

pulse then took on the worst condition, was small, weak, frequent,

empty, and as if dissolving; in a more advanced stage, unequal and

fluttering, until it became completely extinct. Patients were affected

with hallucinations[819]; they were sleepless, despaired of their

recovery, and were usually covered suddenly with an ill-savoured

perspiration over the whole body, whence the disorder was likewise

called _Diaphoresis_. Sometimes, however, a washy sweat broke out,

first on the face and neck. This then spread itself over the whole

body; assumed a very disagreeable odour, became clammy and like water

in which flesh had been macerated, and ran through the bed-clothes in

streams, so that the patient seemed to be melting away[820]. The breath

was short and panting almost to annihilation (insustentabilis). Those

affected were in continual fear of suffocation[821]; tossed to and fro

in the greatest anguish, and with _a very thin and trembling voice_

uttered forth only broken words. They constantly felt an insufferable

oppression in the _left side_, or even over the whole chest[822]; and

in the paroxysms which were ushered in with _a fainting fit_, or were

followed by one, _the heart was tumultuous and palpitated_, without

any alteration in the smallness of the pulse[823]. The countenance was

_pale as death_, the eyes sunk in their sockets, and when the disease

took a fatal turn, all was darkness around them. _The hands and feet

turned blue_; and whilst the heart, notwithstanding the universal

coldness of the body, still beat violently, they for the most part

retained possession of their senses. A few only wandered a short

time before death, while others were even seized with convulsions

and endowed with the power of prophecy[824]. _Finally, the nails

became curved on their cold hands_, the skin was wrinkled, and thus

the sufferers resigned their spirit without any mitigation of their

miserable condition[825].

A striking resemblance is plainly perceived, from this description,

between the ancient cardiac disease and the English Sweating Sickness

in the most exquisite cases of each. In both the same palpitation of

the heart, the same alteration of the voice, the same anxiety, the

same impediment to respiration, and thence the same affection of the

nerves of the chest, the same ill-scented sweat, and, by means of

this sweat, the same fatal evacuation; in short, all the essential

symptoms arising from the same circle of functions. For in the sweating

pestilences of the ancients[826], as well as the moderns, the nerves of

the abdomen remained unaffected; the liver, intestines, and kidneys,

took no part in the primary affection; the diaphragm, as in the English

Sweating Sickness, formed the partition. Hence the acute _Aretæus_ did

not hesitate to call the cardiac disease _fainting_ (syncope), with

certainly an unusual extension of the notion implied by this term,

which in its common acceptation excludes the turbulent commotion of the

heart. In the affection of the brain some difference occurs, for though

the hallucination afforded an unfavourable prognostic in both diseases,

yet the fatal stupor was peculiar to the English Sweating Sickness, no

observer having made mention of it in the cardiac disease.

Greater and altogether essential differences between this affection

and the English Sweating Sickness appear in another respect. There

is every reason to suppose that the cardiac disease first appeared

in the time of _Alexander_ the Great, that is to say, at the end of

the fourth century before Christ; for the Hippocratic physicians

were unacquainted with it, _Erasistratus_, who was body physician

to Seleucus Nicator, and was a universally celebrated professor at

Alexandria under the first Ptolemy, being the first to mention it. If

that age be compared even superficially with that of Henry the VIIth

and Henry the VIIIth; and Africa, Asia Minor, and the South of Europe

with England, we shall easily be convinced that the two diseases,

notwithstanding the agreement in their main symptoms, could not be

the same; moreover, much was comprehended by the ancients under the

name of morbus cardiacus, which, on a nearer examination, proves not

to be one and the same definite form of morbid action: for sometimes

this affection is spoken of as an independent disease; sometimes it

is mentioned only as a symptom superadded to others—as a kind of

transition from other very various diseases, such as has occurred in

modern times. _Soranus_ mentions, as such diseases, continued fevers,

accompanied by much heat[827]; and reckons among them the “Causus,”

that is, an inflammatory bilious fever, to which _Aretæus_ also saw

the cardiac disease superadded. These fevers passed, on the fifth or

sixth day, into the cardiac disease, and such a transition occurred

chiefly on the critical days[828]. In a similar sense _Celsus_ speaks

even of _Phrenitis_, under which name we are here to understand all

inflammatory fevers accompanied by violent delirium, with the exception

of actual inflammation of the brain. Thus we see that the cardiac

disease arose and increased on a very different soil from other

diseases, and was, to furnish an ancient example, as far from being

independent under these circumstances as _lethargy_ was in similar

cases.

But there was doubtless an independent idiopathic form of the cardiac

disease. Whether this was febrile or not, the most celebrated

physicians of ancient times were not agreed. Now, how could they ever

have differed upon the subject, if the cardiac disease had always

appeared only as a sequela on the fifth or sixth day of inflammatory

fevers? _Apollophanes_, a disciple of Erasistratus, and physician to

_Antiochus the First_, considered it, with his master, as constantly

febrile, and his opinion prevailed for a long time: perhaps he was

in the right, for it is probable that in the first half of the third

century, the disorder was much more violent than at a subsequent

period. His celebrated contemporary, _Demetrius_ of Apamea, disciple

of Herophilus, affirmed, that he had recognised fever only in the

beginning of the disease, and that it disappeared in its further

progress. Very soon, most physicians decided that it was not febrile,

but _Asclepiades_ distinguished a febrile and a non-febrile form of

the cardiac disease, and it is certain that this physician was a very

accurate observer. _Themison_ and _Thessalus_ also agreed with him.

_Aretæus_ described, in a cursory manner, the febrile form only, and

perhaps was not acquainted with any other. _Soranus_ followed, in the

essential points, _Asclepiades_, the founder of his school; and later

writers generally regarded the inward heat, the hot breath, and the

burning thirst—symptoms which were occasionally less marked, as proofs

of the febrile nature of the disease. Numerous theoretical views,

belonging to particular schools, of which we do not here treat, were

intermingled with these, and upon the whole, that form seems to have

been esteemed as non-febrile, in which the signs of feverish excitement

appeared less marked. In all cases the cardiac disease set in with

external coldness, and with a small contracted quick pulse, symptoms

which with certainty indicate fever[829].

Respecting the course of the cardiac disease, we are not furnished with

sufficient information. It was no doubt very rapid, for the frame could

not long endure symptoms of so violent a kind, and the disorder must of

necessity soon have come to a crisis; yet from the ample directions for

treatment, we may conclude that it lasted at least some days. If the

perspiration was well surmounted, patients seemed to recover rapidly,

and their sufferings appeared to them, according to the expressions of

_Aretæus_, like a dream, out of which they awoke to a consciousness of

the increased acumen of their senses[830]. But the termination was not

always so fortunate. The disease was very dangerous, and in many, after

the occurrence of an incomplete crisis, an insidious fever remained

behind, which ended in a consumption[831]. The whole phenomenon was

altogether peculiar, and among existing diseases there are none which

bear any comparison with it.

There must therefore have been something in the whole state of

existence among the ancients which favoured the formation of the

cardiac disease. That it arose oftener in summer than in winter, that

it attacked men more frequently than women, and especially young people

full of life, and hot-blooded plethoric persons, who used much bodily

exercise, we learn from credible observers[832]. In this respect,

therefore, it bore a resemblance to the English Sweating Sickness. We

may also add, that indigestion, repletion, drunkenness, as likewise

grief and fear, but especially vomiting and the employment of the bath

after dinner, occasioned an attack of the malady[833]. Let us call to

mind the habits of the ancients. It was in the time of _Alexander_ that

oriental luxury was first introduced. Gluttony became a part of the

enjoyment of life, and warm baths a necessary refinement in sensuality,

which just at this time were philosophically established by _Epicurus_;

nor was this the last instance in which philosophers encouraged the

errors and infirmities of human society.

Here, again, therefore, as in the English Sweating Sickness, we meet

with _the relaxed state of skin, and the foul repletion_ engendered by

the same indulgence in sensuality which we have found to exist in the

sixteenth century. How this corruption of morals increased, and to what

a frightful height it was carried among the Romans, it is not necessary

here further to elucidate; and we may take it for a fact, that in

consequence of it, the general constitution of the ancients underwent a

peculiar modification; that this relaxation of skin and gross repletion

were propagated from generation to generation; and that, as among

chronic diseases, those of _a gouty character_ were its more frequent

results, so among the inflammatory, _the cardiac disease_ made its

appearance as the general effect of this kind of life.

Where, however, such a system of life existed among whole communities,

the original and peculiar occasion was not needed in every individual

case to bring the predisposition for a disease which propagated itself

by hereditary taint, to an actual eruption. Shocks to the constitution

of quite a different kind were often sufficient for the purpose. Thus,

among the Romans, it was by no means always the case, that gluttony

and relaxation of the skin immediately gave rise to the cardiac

disease; while, on the other hand, the usual faintness, induced by too

copious blood-letting, passed into this impetuous agitation of the

heart, accompanied by colliquative sweats[834]; and all overviolent

perspirations in other diseases were apt to take the same dangerous

course[835]. We must here also take into account a practice among the

Romans, which was very injurious, and yet rendered sacred by the laws;

namely, visiting the public baths late in the evening, just after the

principal meal, and awaiting the digestion of their food in these

places of soft indulgence[836]. How much must the tendency of sweating

disorders have been favoured by these means!

Surmises founded on the facts already stated, can alone be offered

respecting the nature of the ancient cardiac disease. The ancients

give us no certain intelligence upon it; for their mode of observing

did not lead to that object at which modern medicine aims. _That the

cardiac disease was not of a rheumatic character_ seems deducible from

several circumstances—from the quality of the atmosphere in southern

climates, which is not so favourable to rheumatic maladies, as to give

rise to a distinctly defined form of that complaint throughout a period

of five hundred years; from the nature of the so-called inflammatory

fever, which exhibited no rheumatic symptoms in its course; and

lastly, from the treatment of the cardiac disease, for it was a common

practice to cool down the “diaphoretic” patients in the midst of their

perspiration, by sponging them with cold water, to expose them to

the air, and some physicians went so far as to advise cold baths and

affusions[837]. How could they have ventured upon such remedies if the

cardiac disease had been of a rheumatic nature?

In the sweating fevers of the sixteenth century, every abrupt

refrigeration, every exposure of the skin, was fatal. It is thence to

be inferred, _that the English Sweating Sickness differed from the

ancient cardiac disease in its rheumatic character_; even although

both diseases were founded in common on an impure gross repletion and

relaxation of skin, and the essential phenomena of both went through

the same course: not to advert to other differences which are manifest

from what has been stated.

The remaining treatment of the cardiac disorder should not be

altogether passed over in this place, because it shews very clearly the

general style of thinking of the medical profession, as also certain

metaphysical excitations which are innate in that profession, and of

which there is therefore a repetition in all ages. For whilst some

proceeded with commendable care and caution, and _Aræteus_ feared[838]

a fatal result from the slightest error, others again, would fain

render excited nature obedient to their rough command by means of

the most violent remedies. It, therefore, occasionally happened that

in their over hasty activity they were unable to distinguish between

a salutary perspiration and a dangerous “diaphoresis.” This they

suppressed at all hazards, and thus sent their patients to the shades

of their fathers. Others forthwith flew to Chrysippic bandaging, the

great means of suppressing profuse evacuations, and even violent

spasms[839]. Others were for obviating the debility as quickly as

possible by means of nourishing diet; and overloaded the stomach, as

if the recovery of strength depended entirely upon eating. Others

allowed as much wine as possible to be drunk for twenty-four hours

together, even to the extent of producing intoxication[840]; and

_Asclepiades_ selected for this extraordinary death-bed carousal the

Greek salt wine[841], for the sake of bringing on a diarrhœa, whereby

the opened pores of the skin might again close, and the too mobile

atoms might be carried towards the bowels. With the same object he

ordered active clysters[842], for if they succeeded in causing a full

evacuation, he maintained that the perspiration must necessarily be

arrested! _Endemus_, of the Methodic sect, recommended even clysters

of cold water[843], and whatever else the rashness of medical men had

fool-hardily contrived; acting on the ancient notion, that severe

diseases always required violent remedies. _Aretæus_ recommended

blood-letting, which others pronounced to be nothing short of certain

death[844]. He had, however, a notion that the Causus was the

foundation of the cardiac disease, and perhaps he was right.

A cautious employment of wine was apparently of great use[845], and

what may excite surprise, physicians gave detailed and frivolous

precepts on the choice and enjoyment of food. If the irritable stomach

rejected this repeatedly, they even went so far, according to the

Roman method, as to make the patient vomit both before and after his

meals, in order that the organ might thus bear the repeated use of

nourishment. It was also asserted that the stomach retained food and

wine better if the body were previously rubbed all over with bruised

onions[846]. All this affords us an insight into the nature of this

remarkable disease, which has now so completely vanished from the

world. Finally, when astringent decoctions proved fruitless, particular

confidence was placed in the application of various powders[847] to the

surface of the body, conjointly with the use of light bed-clothes and

the avoidance of feather-beds, which the effeminacy of the ancients

had already introduced[848]. As astringents they selected pomegranate

bark, the leaves of roses, blackberries, and myrtles, as also fullers’

earth, gypsum, alum, litharge, slaked lime[849], and, when nothing else

was at hand, even common road dust[850]! The efficacy of some of these

extraordinary remedies cannot be denied. At least it has been proved in

modern times with respect to alkalies, which are of a somewhat similar

nature, that they are of great service where there is an abundant

determination of acid towards the skin, and it is very probable that

the perspiration of these diaphoretic patients contained much acid.

SECT. 2.—THE PICARDY SWEAT.

(SUETTE DES PICARDS—SUETTE MILIAIRE.)

The Picardy Sweat is a decided miliary fever, which has often

prevailed, not only in Picardy, but also in other provinces of France,

for more than a hundred years, and even at the present time exists

in some places as an endemic disease[851]. We have pointed out the

affinity between the English Sweating Sickness and miliary fever. Both

are rheumatic fevers—the former of twenty-four hours’ duration, the

latter running a course of at least seven days. In the former there was

no eruption, or if in isolated cases an eruption made its appearance,

it was doubtless subordinate, not essential. In the miliary fever, on

the contrary, the eruption is so essential, that this disease may be

considered as a completely exanthematous form of rheumatic fever.

The history of miliary fever is full of important facts, and the

sweating fever of Picardy forms but a variety of it. The eruption

in itself is of very ancient occurrence, and was most probably, as

at present, observed time immemorial in conjunction with petechiæ,

occurring as a critical metastasis in the oriental glandular plague,

perhaps even in the ancient plague recorded by Thucydides. It also

occasionally accompanied petechial fever, as unquestionably it did

small-pox and many other diseases, in the same manner as we now

see; for the miliary eruption is a very common symptom, which is

easily induced, and increases the danger of various other accidental

complications. This is different, however, from the _idiopathic miliary

fever_, which did not exist either before, or even at the period of

the English Sweating Sickness, but occurred as an epidemic, frequently

mentioned in Saxony, a hundred years later[852], (1652.)

We cannot, therefore, consider this eruptive disease as having

proceeded from the English Sweating Sickness, in the same manner as

the petechial fever had its probable origin in the glandular plague,

even supposing a more decided inclination of the Sweating Sickness

to the eruptive character could be proved than is possible from the

facts afforded. A whole century intervened, and what vast national

revolutions!

This same separation of so long a period makes also against the

supposition, that the English Sweating Sickness was an interrupted

miliary fever, which exhausted its power by a too luxuriant activity

of the skin on the first day, before the eruption made its appearance.

Moreover, the similarity and isolation of all the five epidemic

sweating fevers, as regards the brevity of the course of the disease,

and the absence of all transition forms of any duration, which

certainly would have existed had nature intended gradually to form a

miliary fever out of the English Sweating Sickness, lead to the same

conclusion.

But to return to the miliary fever. Some forms of this disease have

been observed, in which a profuse perspiration, in combination with

nervous symptoms, has endangered life on the first day of the attack;

equally often, too, the eruption has appeared fully formed on the

very first day; and if we duly consider, as we ought, the regular

course of miliary fever whenever it has assumed an epidemic character,

we shall always find, even in that case, a development of symptoms

differing fundamentally from those of the English Sweating Sickness.

If, occasionally, instances of miliary fever occurred, in which no

eruption came out, as was the case recently (in 1821), they were to

be considered in the same light as other acute eruptive diseases,

as, for example, scarlet fever, in which nature indulges in a like

irregularity, without, however, altering the essence of those diseases.

And since, finally, it has been observed in many cases[853], that

the miliary eruption could be prevented by the application of cold

at the commencement, a distinguished modern physician has attached

great consequence to this circumstance, as showing that miliary fever

and the English Sweating Sickness were the same disease[854]; but a

check of this kind is, at all events, impossible in those miliary

fevers where the eruption breaks forth on the first or second day; and

moreover, experience tells us, that many other diseases also, such as

inflammations, rheumatisms, gastric fevers, and even abdominal typhus,

may be arrested in their course, and confined within narrower bounds,

so as not to manifest all their symptoms.

We are, therefore, completely entitled to consider the appearance of

the miliary sweating fevers as altogether a novelty, originating in

the middle of the 17th century, and having no discoverable connexion

with the English Sweating Sickness. There have been in Germany, since

the year 1652, many visitations of miliary fever; but this disease did

not increase much in extent until about the year 1715, when it spread

into France and the neighbouring countries, particularly Piedmont[855],

whilst England remained almost entirely free from it. The French

epidemics were, upon the whole, much more severe than the German; and

on this account we select one of the most ancient, and also the most

recent of them, in order to give a general view of miliary fever, as

compared with the English Sweating Sickness.

The miliary fever first appeared in Picardy, in the year 1718, in le

Vimeux (Vinnemacus pagus), a district on the north of the Somme and

on the south of the Bresle and the department of the Lower Seine. It

increased annually in extent; most places in Picardy were visited by

it, and it was not long before it was seen in Flanders[856].

We are still in possession of a very distinct account, which we will

here detail, of an epidemic at Abbeville in the year 1733, where the

miliary fever had existed fifteen years previously. There were scarcely

any premonitory symptoms, but the disease commenced at once with

pinching pains in the stomach, extreme prostration of strength, dull

headache, and difficulty of breathing, interrupted by sighing. Patients

complained of violent heat, and were bathed in a pungent sweat of foul

odour, while nausea was occasionally felt. Sparks appeared before the

eyes, and _the countenance became flushed_. Patients were tormented

with burning thirst; and yet the tongue was as moist as in perfect

health. The pulse was frequent and undulating, without hardness; and

in the course of _a few hours_, an insufferable itching came on over

the whole body, accompanied by distressing jactitation: upon this,

thickly studded, _red, round pustules_, not bigger than mustard-seeds,

broke out, wherefrom patients emitted an extremely disagreeable urinous

odour, which was imparted to those who were about their persons.

Sometimes they had evacuations, at other times they suffered from

constipation, but all complained of want of sleep; and when they felt

an inclination to doze, they were again aroused by fresh chilliness.

Many bled at the nose till they fainted; and with women, the menstrual

discharge often appeared, though not at the proper time. The urine was

at times deficient in quantity, at others discharged in abundance,

and without any critical signs; if pale and plentiful, it betokened

delirium; then the eyelids twitched convulsively, a humming noise

commenced in the ears, and the patient tossed about restlessly. The

pulse became strong, irregular, and, like the breathing, very quick.

The countenance grew redder and redder; and soon after, the sufferers,

as though struck by lightning, were seized with lethargy, and expired,

generally in the act of coughing and spitting blood.

Such was the nature of the disease when it attacked many at once: there

were, however, several varieties. With some the miliary vesicles broke

out on the _second_ day, with others not before the _third_; and if

all went on favourably, they lost their redness on the _seventh day_,

and _the skin all over the body scaled off like bran_. The fever was

sometimes extremely violent; at others, without apparent cause, very

mild; at least one might be deceived at the commencement of the attack,

by the apparently favourable symptoms; for those who in the morning

had scarcely any notable degree of fever, who neither suffered from

any anxious sensation nor violent heat, in whom no subsultus tendinum

was perceptible, no want of perspiration, nor any retrocession of the

eruption, were sometimes towards evening seized with phrenzy, and died

in a state of lethargy. Evacuations, which alleviate other diseases,

made this miliary fever worse. Favourable symptoms could never be

depended on. In the midst of profuse perspiration the patient died,

either from constipation or diarrhœa. A copious discharge of urine

was a bad sign; composure was succeeded by delirium, cheerfulness by

lethargy: the disease was throughout treacherous and disguised. It

was particularly necessary for those suffering from pleurisy or any

inflammatory fevers to be guarded against its approach. Many fell

sacrifices to this epidemic who thought themselves in a state of

convalescence; and with such it was easier to foretell than to prevent

the consequences. In cases of this kind the miliary vesicles were less

red and grew pale sooner; but if the disease attacked a healthy person,

then they were redder, and continued longer. Of those who recovered,

not a few suffered for many months, nay, even for a whole year, from

night perspirations, without fever or sleeplessness, but with an

eruption of little miliary vesicles, which disappeared[857] again on

the slightest exposure to cold. The later miliary epidemic fevers in

France, which are distinguished by the name of the Picardy Sweating

Sickness, are generally very well described[858]; so much so, that we

have few epidemics of modern times whose course and succession we can

trace so well. But the epidemic of 1821, which raged in the departments

of the Oise, and of the Seine and Oise, from March to October, has been

observed by all with the greatest care, including men of distinguished

talent[859].

We shall give the description of this disease. There were no constant

premonitory symptoms; it often broke out quite suddenly, but many

complained some days before of debility, despondency, want of appetite,

nausea, headache; sometimes also of giddiness and slight chilliness.

Many retired to rest in health, and awoke during the night with the

disease, covered with a perspiration, which ceased only with death or

recovery. With some the sweating was preceded for some hours, or even

only for some moments, by a scarcely perceptible feverish commotion,

accompanied with burning heat, or with a _sensation of pain_ which ran

through every limb, and nearly always with spasms in the stomach. With

others the disease announced itself by lacerating rheumatic pains,

which gradually increasing, they became bed-ridden. The mouth was

foul, the taste at times bitter, the tongue white, more rarely tinged

with yellow, and thus it remained till the patient was restored. The

sufferer was shortly covered with _a thick, peculiarly fetid sweat_,

that certainly produced alleviation, but became very intolerable to

him from its unpleasant stench, which was even communicated to the

clothes of the bystanders. In the mean time it was discovered by the

pulse, that the fever had considerably abated; but, on the third day,

the patient was seized with convulsive _spasms in the stomach_, great

_oppression at the chest_, and a sensation of suffocation—symptoms

which caused him insupportable anguish. These attacks accompanied by

hiccup and eructation, continued for several hours, and returned from

time to time, an eruption, partly papular, simultaneously breaking out

first on the neck, then on the shoulders down to the hands and breast,

less frequently on the thighs and face. The little pimples were of a

pale red colour and conical, with glistening heads, and between them

appeared innumerable small miliary pustules, filled with transparent

serous fluid, which soon thickened and assumed a whiter hue. At the

time and previous to the breaking out of the exanthem, the patient

experienced a very severe _burning and pricking sensation in the skin_,

which nevertheless sometimes occurred on the second or fourth day, and

which increased sometimes in one part, sometimes in another, when the

sweating declined.

Towards the fifth day, however, after the sweating had entirely ceased,

the complaint grew worse again. The spasms and paroxysms of suffocation

returned, and they were succeeded by renewed eruptions of the exanthem;

a decided improvement, however, shortly took place; the little pimples

lost their redness, the miliary vesicles dried away, and at a period

from the seventh to the tenth day recovery commenced under _a general

exfoliation of the cuticle_. Sometimes the eruption did not appear,

whether the patients were under medical treatment, or left to their own

guidance, but with those few in whom there was an absence of miliary

vesicles, that peculiar pricking and itching of the skin did not take

place.

Between the fifth and seventh day the patients usually complained of

great weakness, and had a desire to eat. A few tablespoonfuls of wine

then agreed with them very well; for the rest, neither thirst nor

lethargy was observable, but it was particularly remarkable that the

urine was clear and abundant. Up to the seventh day a confined state

of bowels was usual, and, with the exception of the already mentioned

attacks of tightness and oppression, the breathing remained free,

though with great sleeplessness, during the whole malady. Nothing

morbid was to be observed in the chest, and the patients lay stretched

out at full length, so that there was no occasion at any time to raise

their heads.

Such was the regular course of this miliary fever, but its progress

was often accelerated by very dangerous symptoms, and occasionally it

proved fatal within a very few hours. If at the time of the attack the

patients were very restless and talkative, the eyes glistening, the

pulse, without being hard, tumultuous, and the edges of the tongue

reddened, delirium soon succeeded and then convulsions and death.

Great depression of the spirits was a very bad symptom; bleeding was

never of any avail, yet the menstrual discharge did not interrupt

the course of the disease. There was in general a great degree of

malignancy perceptible in the malady, as was also rendered apparent

by the course of the epidemic. If the miliary Sweating Fever broke out

in a fresh place, two or three persons only were thereupon attacked,

and that favourably, which led to a supposition that the evil had all

passed away, for during the next fifteen or twenty days, not any fresh

attacks were heard of. Suddenly, however, the epidemic reappeared

with increased virulence. The great number of the sufferers spread

consternation and terror amongst the inhabitants, and the cases of

death became frequent. After this first burst of fury, the epidemic

grew more mild again, so that many patients were not confined to

their beds at all. This mitigation of the miliary fever was likewise

manifested[860] by the prolongation of its course beyond the seventh

day.

If we compare this epidemic with the one observed at Abbeville in 1773,

we shall find between them but very trifling differences, which would

appear still more clearly in some of the intermediate visitations,

thus conforming to what has been observed in other eruptive maladies.

It is consequently evident that the miliary fevers[861] which have

appeared in France in recent times, do not differ in any essential

point from those of more ancient date. The surest proof of their

identity is, their persistence for nearly two centuries; and from the

manner in which they have presented themselves to observation, they

are to be considered as distinct from the English Sweating Sickness,

though certainly allied to it. It would exceed our limits to pursue

this inquiry further, but it may be as well to give the following short

catalogue[862] of the most important miliary epidemics.

1652. Leipzig.

1660. Augsburg.

1666. Bavaria.

1672. Hungary.

1675. Hamburgh.

1680. Germany to a great extent.

1689. Philippsburg.

1690. Stuttgard.

Düsseldorf.

Erfurt.

Jena.

1694. Berlin.

1700. Breslau.

1709. Dantzic, Marienburg.

1712. Mümpelgart.

1713. Saint Valery. (Somme.)

1714, 15. Laybach.

1715. Breslau.

Turin.

1718. Tübingen.

Abbeville. (Somme.)

1720. Canton de Bray. (Lower Seine.)

1723. Francfort on the Maine.

1724. Turin.

Vercelli.

1726. Acqui.

Guise. (Aisne.)

1728. Chambéry, Annecy, St. Jean de Maurienne. (Savoy.)

Carmagnola.

Vercelli.

Ivrea.

Biella.

1729. Vienna. (Austria.)

1730. Pignerol.

1731. Fossano.

1732. Nizza.

Rivoli.

1733. Fossano.

Asti.

Lanti.

Acqui.

Basle.

Silesia.

1734. Strasburg. (Lower Rhine.)

Acqui.

Lanti.

1735. Trino.

Lanti.

Fresneuse. (Lower Seine.)

Vimeux. (Seine et Oise.)

Orleans. (Loiret.)

Pluviers. (Loiret.)

Meaux. Villeneuve.

Saint George. (Seine et Marne.)

Bohemia.

Denmark.

Sweden.

Russia.

1738. Luzarches, Royaumont. (Seine et Oise.)

Susa.

Crescentino.

1740. Caen. (Calvados.)

Provins. (Seine et Marne.)

Vire. (Calvados.)

Berthonville. (Eure.)

Falaise. (Calvados.)

1741. Rouen. (Lower Seine.)

Tartana.

Valencia.

Alexandria.

London.

1742. Caudebec. (Lower Seine.)

Ceva.

Turin.

Sorillano.

Alba.

Ivrea.

Cherasco.

Fossano.

1743. Villafranca.

1744. Acqui.

1746. Zurich.

1747. Paris. (Seine.)

Beaumont. (Seine et Oise.)

Chambly. (Oise.)

Modena.

Lodi.

Mantua.

Piacenza.

1750. Schaffhausen.

Bern.

Geneva.

Beauvais. (Oise.)

1751. Villafranca.

1752. Fernaise. (Seine et Oise.)

1753. Susa.

1754. Valepuiseux. (Seine et Oise.)

1755. Novara.

1756. Cusset. (Allier.)

Boulogne. (Pas de Calais.)

1757. Montaigu les Combrailles. (Puy de Dôme.)

1758. Amiens, environs. (Somme.)

1759. Paris. (Seine.)

Guise. (Aisne.)

Caudebec. (Lower Seine.)

1760. Alençon. (Orne.)

1763. Vire. (Calvados.)

1763, 64. Bayeux. (Calvados.)

1765. Balleroy, Basoques. (Calvados.)

Saint-George, Saint-Quentin. (Calvados.)

1766. Campagny. (Calvados.)

1767. Thinchebray, Truttemer. (Orne.)

1768, 69. St. Quentin. (Aisne.)

1770. Louviers. (Eure.)

1771. Montargis. (Loiret.)

1772. Hardivilliers, environs.

1773. Hardivilliers. (Oise.)

1776. Laigle. (Orne.)

1777. Jouy. (Seine et Oise.)

1782. Castelnaudary. (Aude.)

Boissy Saint-Léger. (Seine et Oise.)

1783. Beaumont. (Seine et Oise.)

1791. Méru. (Oise.)

1810. Nourare, Villotran. (Oise.)

1812. Rosheim, and many other places. (Lower Rhine.)

1821. La Chapelle, Saint-Pierre and sixty places around. (Oise; Seine

et Oise.)

SECT. 3.—THE ROETTINGEN SWEATING SICKNESS.

We now come to a phenomenon which, notwithstanding its short duration

and very limited extension, is one of the most memorable of this

century. Up to the present time, its real importance has not been

recognised, because the clouds of self-sufficient ignorance have

prevented our taking a survey of the formation of diseases, throughout

long periods of time. It has been sunk for an age in the sea of

oblivion, from whence we will now draw it forth to the light of day.

In November, 1802, a very hot and dry summer had been succeeded by

incessant rain. Thick fogs spread over the country, and enveloped such

places in central Germany as were inaccessible to ventilation. Amongst

others, the small Franconian town of Roettingen, situated on the river

Tauber, and surrounded by mountains[863]. Scarcely had a few weeks

elapsed, when unexpectedly, towards the 25th of November, an extremely

fatal disease broke out in the town, which was without example in the

memory of its inhabitants, and totally unknown to the physicians of the

country.

Strong vigorous young men were suddenly seized with _unspeakable

dread_; the heart became _agitated_ and _beat violently against_ the

ribs, a _profuse, sour, ill-smelling perspiration_ broke out over

the whole body, and at the same time, they experienced a _lacerating

pain_ in the nape of the neck, as if a violent rheumatic fever had

taken possession of the tendinous tissues. This pain ceased sometimes

very quickly, and if it then shifted to the chest, the distressing

palpitation of the heart recommenced; a spasmodic trembling of the

whole body ensued; the sufferers fainted, their limbs became rigid,

and thus they breathed their last. _In most cases, all this occurred

within four and twenty hours._ They did not all, however, succumb under

the first attack, but as soon as the accelerated pulse had sunk to the

lowest ebb of smallness and feebleness, a corresponding effect being

observable in the respiration, the violent pain would in some cases

return to the outward parts. The patient then felt a benumbing pressure

and stiffness in the nape of the neck; and the pulse and respiration

became restored again as in health, but the perspiration continued to

pour incessantly down the skin.

This apparent safety was, however, very deceptive, for a renewed

palpitation of the heart unexpectedly commenced, accompanied by a

feeble pulse; and then death was often inevitable. It was remarkable,

that the patients, though bathed in perspiration, had very little

thirst, and the tongue was not dry, nor ever even foul, but retained

its natural moisture. With most, however, the urine was scanty; as

the skin, under the increasing debility, permitted too much fluid to

stream forth through its pores. _If the disease passed off without

heating sudorifics, then in general no eruption made its appearance._

The malady then continued till the sixth day, but on the first only,

did it display its malignant symptoms, for by the second, the sweating

diminished and lost every unfavourable quality, so that increased

transpiration of the skin, without any other symptoms of importance,

alone remained, and on the sixth day the patient was perfectly

restored.

Had there been in Roettingen a physician at hand from the commencement,

_well skilled in medical history_, and who would have adopted the old

English treatment of the Sweating Sickness, this new fever would have

appeared but as a perfectly mild disease, and would certainly have

carried off but few of the inhabitants of this peaceful little town.

As it was, however, the scenes of Lübeck and Zwickau were renewed,

and it seemed as if the innumerable victims to the hot treatment, and

to _Kegeler’s_ truculent medical work, had descended to the grave in

vain. _The sufferers were, as in the sixteenth century, literally

stewed to death!_ for the moment the people imagined that they knew

how nature meant to escape, they ordered feather-beds to be heaped

on the perspiring patient, so that the mouth and nose alone remained

uncovered. Doors and windows were tightly closed, and the stove emitted

a glowing heat, whilst a most intolerable odour of perspiration

streamed forth from beneath the broad and lofty beds; added to which,

that two and even more patients were often lying in the same room;

nay, even stowed together under the same mountain of feathers, and in

order that inward heat might not be wanting, pots of theriaca were

swallowed, and the patient was incessantly plied with elder electuary.

Thus the bad humours were expelled together with the perspiration;

and whether the sufferers were suffocated, or surmounted, as by a

miracle, this mal-treatment of nature, a conviction was felt, that the

most salutary remedies had been employed, and when at last, eruptions

of various colours broke out, it was considered as certain, that the

poison had been carried off in them. The citizens of Roettingen,

therefore, fell into the same erroneous opinion, which, upheld by

medical schools, had, time immemorial, increased inflammatory diseases,

particularly the exanthematous, and caused them to become malignant.

The above-mentioned eruptions were of various sorts; miliary vesicles

of every form and colour, filled with an acrid fluid; actual blistery

eruptions, (pemphigus,) and even petechiæ; and it is to be observed,

that the patients, during the first days of the sweating fever, never

suffered from that peculiar pricking sensation over the whole body,

which precedes the eruption of miliaria, but complained only, and that

not always, of a local itching, where the eruption had broken out. It

was equally rare to observe a regular desquamation of the skin, and it

is therefore to be assumed, that _the eruptions were only symptomatic_,

and not by any means necessarily connected with the disease, as in the

decidedly miliary fevers.

The disease excited, from its very commencement, the greatest

consternation; and as it was increased, even from the first days of

its appearance, by the sudorific system of treatment, deaths were

multiplied; the continual peal of funeral bells struck mortal terror,

as of old at Shrewsbury, into the hearts of both sick and healthy; and

this oppressed little town was shunned as a pesthole by the inhabitants

of the surrounding neighbourhood. At the commencement of the disease,

they were entirely without medical advice, till a skilful physician

arrived from the vicinity[864], and as _most of the inhabitants_ were

already attacked with the sweating fever, he immediately prescribed

the proper treatment. But the powers of one man are not sufficient,

amid such confusion, to contend with the deeply rooted prejudices of

the people, and so they continued in most houses to expel by heat and

theriaca both perspiration and life together; till at last, on the

third of December, _Dr. Sinner_ of Würzburg arrived, without whom the

remembrance of this remarkable disease would have been obliterated, and

conjointly with his gallant colleague, like the anonymous physician

formerly in Zwickau, subdued the destructive prejudices of the people.

He found eighty-four patients[865] under piles of feather-beds, who,

when pure air was admitted, breathed once more freely, and by a prudent

cooling system, all recovered easily, and without danger, one only

excepted. His method reminds us of the old English treatment[866].

The disease was confined entirely to Roettingen, it did not make its

appearance anywhere beyond the gates of this little town. On the fifth

of December, however, clear, frosty weather set in; from that time no

new cases occurred, and all traces of this Roettingen sweating fever,

which was never either preceded or followed by miliary fever in any

part of Franconia, have from that time disappeared.

The resemblance of this fever to the English Sweating Sickness is

manifest, and is proved even by the short (_only ten days’_) duration

of the visitation, which, as we have stated, is a most essential

characteristic of the English sweating epidemic, at least as it

appeared in Germany, the miliary epidemics always having lasted a much

longer period. But if we confine ourselves merely to the symptoms of

the disease, we shall find, that in the Roettingen sweating fever,

there are, throughout, none that can be considered essential, except

the _palpitation of the heart, accompanied with anguish_, the _profuse

perspiration_, and the _rheumatic pains in the nape of the neck_,

which never were wanting in any case; and the very same symptoms are

clearly and perceptibly to be discerned in like proportion as compared

with others, in the representation of the English Sweating Sickness;

whereas, the eruptions were altogether as unessential as in the

epidemic of the sixteenth century. The irritability of the skin, and

tendency to dangerous metastases, were less marked in the Roettingen

fever than in the English Sweating Sickness; for the patients could,

without injury, change their linen in the midst of the perspiration,

which, in the English Sweating Sickness, could not have been done

without fatal consequences; but this difference can easily be accounted

for, from the greater degree of suffering in the latter disease than in

the former. It only now remains to examine the duration of the disease,

and here we plainly perceive that the principal paroxysm was over in

the Roettingen epidemic within the first four and twenty hours, at

least when it was undisturbed by treatment; and the sole symptom which

continued until the sixth day—the increased perspiration, (we speak

here only of perfectly pure cases,) could only reasonably be regarded

as a sequela. The crisis did not occur all on a sudden, as in the

English Sweating Sickness, but this cannot constitute any essential

difference.

We do not hesitate, therefore, to pronounce _the Roettingen fever to

have been the same disease as the English Sweating Sickness_. To give,

however, this phenomenon its proper interpretation—to have a clear

conception of the causes which again drew down from the clouds, into

the midst of Germany, this mist-born spectre of 1529, and allowed it

to expend its brief fury upon a single place, is beyond the power

of human wisdom. Science is not comprehensive enough to discover, in

the crossings of these unknown comet-paths, the moving causes of this

visitation of disease. But as all insight into the works of nature must

be preceded by a strict investigation and search after phenomena in all

countries, at all times, and under all circumstances of development, so

an improved knowledge of diseases and of the whole human system, will

not fail to follow, when the investigations of epidemics throughout

extensive periods have increased in number and success.

_The present age demands such a knowledge of medical men, whose

vocation it is to investigate life minutely in all its bearings. It

demands of them an historical pathology, and to this branch of the

study of nature is the present work intended to contribute._

CHRONOLOGICAL SURVEY.

POLITICAL EVENTS. FIRST VISITATION OF THE SWEATING

SICKNESS.

1461–1483. Louis XI. 1472–1482. Swarms of locusts

1485–1509. Henry VII. in the south of Europe.

1493–1519. Maximilian I. 1480–1485. Wet years.

Mercenary troops are introduced. 1483. Overflow of the Severn,

(the _great water_ of the Duke

1483–1498. Charles VIII. of Buckingham.)

1483–1485. Richard III. 1480 and 1481. Famine in

1483, October. First abortive Germany and France.

attempt of the Earl of Richmond, 1477–1485. Glandular plague

(who had fled to France in Italy.

in 1471,) against Richard III. 1480, 1481. Encephalitis in

The Duke of Buckingham Germany.

executed. 1482. Febrile cerebritis in

1485. Richmond obtains support France, and epidemic pleuritis

from Charles VIII. in Italy.

1485, 25th July. Richmond’s 1483. Glandular plague in

departure from Havre. Spain.

1485, 1st August. Landing at 1484 and 1485. Malignant fever

Milford Haven. in Germany and Switzerland.

1485. From the 1st to the 22d Plague in Spain.

of August, march from Milford 1485. _In the beginning of August:_

Haven to Lichfield and _eruption of the English_

Bosworth. _Sweating Sickness, probably_

1485, 22d August. The battle _amongst Richmond’s_

of Bosworth. Richard III. _mercenary troops. It spread_

falls. The Earl of Richmond _from west to east, and then_

becomes king, under _in a contrary direction._

the name of Henry VII. 1485. _The end of August, in_

_Oxford._

1485, 28th August. Henry’s 1485. _21st September till the_

entry into London. _early part of October, in_

1485, 30th October. Henry’s _London._

coronation. 1485. _The middle of November,_

1481–1492. The wars of Ferdinand _in Croyland._

the Catholic, against 1486. _1st January. Termination_

the Saracens. _of the first epidemic_

1495. Useless war for the _Sweating Sickness._

succession of Charles VIII. 1486. Epidemic scurvy in Germany.

against Alfonso II., (who died Plague in Spain.

in 1495,) and Ferdinand II. 1488–1490. Plague in Spain.

of Naples. The conquest of 1490. First eruption of petechial

the kingdom was again fever in Granada, in the

immediately relinquished. army of Ferdinand the Catholic.

1495. Eruption of the syphilitic

pestilence at Naples,

among the mercenary army

of Charles VIII.

1499. Great plague in London.

SECOND VISITATION.

1485–1509. Henry VII. 1500–1503. Mould-spots (signacula)

1501. His eldest son, Arthur, in Germany and France.

marries Catherine of Arragon,

daughter of Ferdinand 1500. Comet.

the Catholic. 1500. Mortality among cattle

1502. Prince Arthur dies. in Germany.

Prince Henry (VIII.), second 1502. Very extensive destruction

son of Henry VII., is affianced of cultivation in Germany

to Catherine of Arragon. by blights of caterpillars.

The internal condition of England 1503. Glandular plague, and

is altered by Henry VII. destructive epidemics in

The towns begin to rise Germany and France.

importance, and the sciences 1504. Plague in Spain.

to become diffused. A rigorous 1504 and 1505. Encephalitis,

and unjust financial putrid fever, and malignant

system. pneumonia in Germany.

1498–1515. Louis XII. 1505. Plague in Portugal.

1501. conquers Naples in 1505. First epidemic petechial

conjunction with the Spaniards, fever in Italy. The morbid

and is by them activity of the organism

1504. expelled thence. He shewed a decided determination

establishes his power in towards the skin during

Upper Italy. all this period.

1511. Pope Julius II. (1503–1513) 1505. Moist summer. Lamentable

forms the sacred league moral state of England.

against France, into which 1506. _The summer: the Sweating_

enters likewise, in 1512, _Sickness breaks out in_

Henry VIII. The French _London, and continues to a_

lose their power in Italy. _moderate extent, being confined_

1504. Isabella of Castile dies. _to England, until the_

Philip I. of Austria, her _autumn. This second visitation_

daughter Johanna’s husband, _is the mildest of all, and_

succeeds her, his son, _the old English method of_

Charles V., having been born _treatment proves effectual_

in 1500. _everywhere._

1506. Philip I. dies. 1506–1508. Pestilential epidemics

1516. Ferdinand the Catholic in Spain.

dies. 1508. Swarms of locusts in

Spain.

THIRD VISITATION.

1509–1547. Henry VIII. 1515. Pestilential epidemics in

1515–1547. Francis I. immediately Spain.

attacks Milan again, 1516. Comet.

and conquers. 1517. Unproductive, but not

1515. the Swiss, in the battle moist summer.

of Marignano. Keeps possession 1510. Great influenza (Coqueluche)

of Milan, and establishes throughout France,

the French dominion in Italy and probably to a still further

until the year 1522. extent. Plague in the north

1516. Cardinal Wolsey changes of Europe.

the policy of England in favour 1517. In the early months epidemic

of Francis I., trachæitis and œsophagitis

1520. then of Charles V. (diphtheritis) in Holland,

1513–1522. Leo X., against lasting only eleven days.

France. Promotes, by a new This epidemic extends towards

bull of indulgences, the outbreak the south, and appears

of the Reformation. in the same summer at

1517. 31st of October, Luther Bâsle.

commences the Reformation. 1517. On the 16th June, earthquake

1519. 12th January, the Emperor in Swabia (and Spain).

Maximilian I. dies. 1517. Encephalitis and other

1519–1556. Charles V. inflammatory fevers in Germany.

1521. Imperial diet at Worms. 1517 _In July, outbreak in_

1517. May: Insurrections of _London of the third visitation_

the operatives in London. _of epidemic sweating sickness;_

1517. In the autumn and winter, _it spreads with great_

Henry VIII. frequently _malignity all over England,_

changes the residence of his _and among the English at_

Court in consequence of the _Calais; in the sixth week_

Sweating Sickness and the _it attains its greatest_

Plague. _violence, and terminates in_

1518. 11th February, Queen _December. Ammonius, of Lucca,_

Mary is born. _and many distinguished and_

1518. The College of Physicians _learned persons in Oxford_

in London is founded _and Cambridge are carried_

by Linacre. _off by it._

1521. Henry VIII. opposes 1517. In December, immediately

Luther, and obtains the title after the Sweating Sickness,

of “Defender of the Faith.” a plague occurs in

(_Thomas More._) England and lasts all the

winter.

1517. Small-pox breaks out in

Hispaniola.

FOURTH VISITATION.

1524. October, Francis I. 1524. Great plague at Milan,

passes Mont Cenis, and is 1527. Inundations in Upper

1525. beaten at Pavia and captured. Italy.

1526. 14th January. Peace of 1527. 11th August, a comet.

Madrid. 1527. Plague in the imperial

1526. Clement VII. (1523–1534) army in Italy, after the sacking

becomes the head of of Rome; and in Wittenberg.

the Holy League against the 1528–1534. Years of famine,

Emperor. with a prevalence of moisture

1527. 6th May. Rome is vanquished and heat.

by the imperial army 1528. Repeated inundations.

and sacked. Continual south winds and

1528. A French army, under summer fogs in Italy. Second

Lautrec, conquers the greatest great epidemic petechial

part of Italy, and fever there.

commences 1528. Destruction of the French

1528. 1st May, the siege of army before Naples by a

Naples. Lautrec dies in pestilential Spotted Fever.

August. 1528. Cold spring and moist

1528. 29th August, the siege of summer in France.

Naples is raised. The remains 1528–1532. Warm winters, moist

of the French army summers. Repeated failures

are made prisoners. of harvest, and great famines

1528. Charles V. challenges in that country.

Francis I. to single combat. 1528. The Trousse-galant carries

1529. 5th August, Francis I. off a fourth part of the

concludes the unfavourable inhabitants of France in this

peace of Cambray. Termination and the following years.

of the French dominion 1528. Wet and mild winter.

in Italy. The Reformation Moist summer with fogs.

in England is Failure in crops, and famine

retarded. in England.

1527. Scruples of Henry VIII. 1528. _At the end of May: outbreak_

respecting his marriage with _in London of the Fourth_

Catherine of Arragon. Various _epidemic Sweating Sickness._

negotiations on the subject _It spreads with great_

in the following years. _malignity, and with much_

Cardinal Wolsey falls into _disturbance of social life,_

disgrace. Thomas More becomes _all over England; carries off_

chancellor. _many distinguished persons,_

1528. Henry VIII. retires to _and terminates in the winter._

Tytynhangar in consequence _This year it remains confined_

of the Sweating Sickness. _to England, and does_

1532. Separation of the king _not return in the following_

from Catherine. Mary is excluded _year._

from the government. 1528. Continual south-east

1533. January, Anna Boleyn winds. Great drought.

becomes queen. The Reformation Swarms of locusts and fiery

is introduced. meteors in the north of

1535. Thomas More and Fisher Germany.

are executed. 1529. Earthquake in Upper

1536. Anna Boleyn is executed. Italy. Sanguineous rain at

Jane Seymour becomes Cremona. A comet in July

queen. Dies 1537. and August.

1537. Anne of Cleves becomes 1529. Mild winter in Germany.

queen. Separation after six The spring begins in February.

months. Great moisture

1541. Catherine Howard, queen, throughout the summer. General

and executed one year and dearth in March. Disease

six months afterwards. among the porpoises in

1544. Catherine, queen. the Baltic. Unwholesomeness

1547. 13th December, Henry of the river fish in the

VIII. dies. north of Germany. Disease

1521. Plots of the Iconoclasts among birds. Languor resembling

in Zwickau and Wittenberg. syncope in Pomerania.

1523–1525. Peasant war. On Frequent suicides

the 15th May, battle of in the March. In the middle

Frankenhausen. of June a flood of rain

1529. Imperial Diet at Spires. lasting four days (torrent of

1529. 22d September-16th St. Vitus) in the south of

October, the Turks before Germany. On the 10th of

Vienna. August, a universal tempest.

1529. 2d October, assemblage 24th of August, and the

of the Reformers in following days great heat.

Marburg. 1529. _25th July, outbreak of_

1530. 25th June, surrender of _the epidemic Sweating Sickness_

the Augsburg confession. Severe _in Hamburgh. Termination_

decrees against the _on the 5th August._

Protestants. _On the 29th July in Lübeck._

1531. League of the Protestant _On the 14th August_

princes at Schmalkalden. _in Zwickau. About the_

Continued danger from the _1st September the English_

Turks. _Sweating Sickness appears_

1532. Imperial Diet at Nuremberg. _to spread universally all over_

The Protestants obtain _Germany. On the 31st August_

security. _in Stettin; termination_

1333–1535. Excesses of the _on the 8th September. On_

Anabaptists at Münster. _the 1st September in Dantzic;_

1536. The Schmalkaldic league _termination on the 6th_

is strengthened. _September. On the 24th_

1538. The Catholic States establish _August in Strasburg. On_

the sacred league at _the 5th, 6th and 7th September_

Nuremberg. _in Cologne, Augsburg_

1540. Paul III. (1534–1550) _and Francfort on the Maine._

confirms the order of the Jesuits, _About the 20th September_

founded in 1534 by Ignatius _in Vienna and among the_

Loyola. _besieging Turks. On the_

1519–1541. Conquest of Mexico, _27th September in Amsterdam._

Peru, Chili, &c. _Termination on the_

_1st October in Antwerp and_

_the rest of the Netherlands;_

_simultaneously, at the end_

_of September, in Denmark,_

_Sweden and Noway. At_

_the commencement of November_

_a universal cessation_

_of the epidemic Sweating_

_Sickness._

1530. In October, overflow of

the Tiber. Bursting of the

dykes, and sudden inundations

in Holland, which were

repeated in 1532.

1531. 1st of August to 3d

September, the comet of Halley.

1532. From 2d October to 8th

November, and

1533. From the middle of June

to August, comets.

1534. Termination of the years

of scarcity, during which

malignant fevers prevailed

in circumscribed localities

throughout Europe.

FIFTH VISITATION.

1542. Maurice Duke of Saxony 1538. Epidemic dysentery in

renounces the league of France.

Schmalkalden. 1540. The hot summer. The

1542. The imperial army which forests take fire spontaneously.

opposes the Turks in Hungary, 1541. Plague in

under Joachim II. of Constantinople.

Brandenburg, is destroyed 1542. Swarms of locusts in the

by sickness. south of Europe, and plague

1546. The 18th of February, in Hungary during the war

Luther dies. of the Turks in that kingdom.

1546. Charles V. takes the field 1543. Plague and petechial

against the Protestants, proclaims fever in Germany. Metz.

the Elector, John Frederick, 1545 and 1546. Trousse-galant

and Landgrave Philip in France, of which

of Hesse, outlaws. Gains 10,000 English die at

1547. 24th April, the battle of Boulogne.

Muhlberg. Raises 1546. Plague in the Netherlands

1548. Duke Maurice to the and France.

electorate of Saxony, and 1547. Petechial fever in the

prescribes the _interim_, which imperial army.

is not accepted by Magdeburg. 1547–1551. Mould spots and

1551. Magdeburg declared to red water in the north of

be under the imperial ban, Germany.

and besieged in vain by the 1549. Caterpillars destroy the

Saxons. herbage, and a mortality occurs

1552. Henry II. of France among cattle in Germany.

(1547–1559), in alliance with The 21st of September

the Protestant princes, takes an aurora borealis.

Metz, Toul, and Verdun. 1549 and 1550. Malignant fever

1552. The treaty of Passau (petechial fever?) in the

secures to the Protestants north of Germany.

equal rights with the 1551. Dry and cold spring;

Catholics. hot and wet summer. Inundations,

1547–1553. Edward VI. nine earthquakes, meteors,

years old. The Duke of mock suns, great tempests,

Somerset governs the kingdom summer fogs.

as Protector. The Reformation 1551. Malignant fever in Swabia:

is favoured, and plague in Spain.

makes progress. Influenza.

1553. Mary persecutes the 1551. In the spring, stinking

and in 1558 loses Protestants, mists on the banks of the

Calais. Severn.

1556. Charles V. abdicates, and 1551. _On the 15th of April_

dies on the 11th of September, _outbreak of the fifth epidemic_

1558, in Spain. _Sweating Fever in Shrewsbury_

_on the Severn. It gradually_

_spreads with stinking_

_mists all over England, and_

_on the 9th of July reaches_

_London. The mortality is_

_very considerable. Foreigners_

_are unaffected, but Englishmen_

_in foreign countries_

_sicken with the English_

_Sweating Sickness. The epidemic_

_terminates on the 30th_

_of September._

1552 and 1553. Malignant fever

in Germany and Switzerland.

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APPENDIX.

A BOKE, OR COUNSEILL

AGAINST

THE DISEASE

COMMONLY CALLED

►THE SWEATE◄,

OR

►SWEATYNG SICKNESSE◄.

MADE BY JHON CAIUS

DOCTOUR IN PHISICKE.

UERY NECESSARY FOR EUERYE PERSONNE, AND MUCHE

REQUISITE TO BE HAD IN THE HANDES OF AL

SORTES, FOR THEIR BETTER INSTRUCTION,

PREPARACION AND DEFENCE, AGAINST

THE SOUBDEIN COMYNG, AND FEARFUL

ASSAULTING OF THE SAME

DISEASE.

1552.

TO THE RIGHTE HONOURABLE

WILLIAM EARLE OF PENBROKE,

LORDE HARBERT OF CARDIFE, KNIGHT OF THE

HONOURABLE ORDRE OF THE GARTER, AND

PRESIDENT OF THE KYNGES HIGHNES

COUNSEILL IN THE MARCHES

OF WALES:

►JHON CAIUS◄

WISHETH HELTH AND HONOUR,

In the fereful tyme of the sweate (ryghte honourable) many resorted

vnto me for counseil, among whōe some beinge my frendes & aquaintance,

desired me to write vnto them some litle counseil howe to gouerne

themselues therin: saiyng also that I should do a greate pleasure to

all my frendes and contrimen, if I would deuise at my laisure some

thīg, whiche from tyme to tyme might remaine, wherto men might in such

cases haue a recourse & present refuge at all nedes, as thē they had

none. At whose requeste, at that tyme I wrate diuerse counseiles so

shortly as I could for the present necessite, whiche they bothe vsed

and dyd geue abrode to many others, & further appoynted in my self to

fulfill (for so much as laye in me) the other parte of their honest

request for the time to come. The whiche the better to execute and

brynge to passe, I spared not to go to all those that sente for me,

bothe poore, and riche, day and night. And that not only to do thē that

ease that I could, & to instructe thē for their recouery: but to note

also throughly, the cases and circumstaunces of the disease in diuerse

persons, and to vnderstande the nature and causes of the same fully,

for so much as might be. Therefore as I noted, so I wrate as laisure

then serued, and finished one boke in Englishe, onely for Englishe mē

not lerned, one other in latine for men of lerninge more at large, and

generally for the help of thē which hereafter should haue nede, either

in this or other coūtreis, that they may lerne by our harmes. This I

had thoughte to haue set furth before christmas, & to haue geuē to your

lordshippe at new-yeres tide, but that diuerse other businesses letted

me. Neuertheles that which then coulde not be done cometh not now out

of season, although it be neuer so simple, so it may do ease

hereafter, which as I trust this shal, so for good wil

I geue and dedicate it vnto your good Lordshippe,

trustyng the same will take this with as good a

mind, as I geue it to your honour, whiche

our Lorde preserue and graunt long

to continue.

At London the first of Aprill.

1552.

THE

BOKE OF JHON CAIUS

AGAINST THE SWEATYNG SICKNES.

Man beyng borne not for his owne vse and cōmoditie alone, but also

for the commō benefite of many, (as reason wil and al good authoures

write) he whiche in this world is worthy to lyue, ought al wayes to

haue his hole minde and intente geuen to profite others. Whiche thynge

to shewe in effecte in my selfe, although by fortune some waies I haue

ben letted, yet by that whiche fortune cannot debarre some waies again

I haue declared. For after certein yeres beyng at cambrige, I of the

age of xx. yeres, partly for mine exercise and profe what I coulde do,

but chefely for certein of my very frēdes, dyd translate out of Latine

into Englishe certein workes, hauyng nothynge els so good to gratifie

theim w^t. Wherof one of _S. Chrysostome de modo orandi deum_, that

is, of y^e manner to praye to god, I sent to one my frende then beyng

in the courte. One other, a woorke of _Erasmus de vera theologia_,

the true and redy waye to reade the scripture, I dyd geue to Maister

Augustine Stiwarde Alderman of Norwiche, not in the ful as the authore

made it, but abbreuiate for his only purpose to whome I sent it, Leuyng

out many subtile thinges, made rather for great & learned diuines, thē

for others. The thirde was the paraphrase of the same Erasmus vpon the

Epistle of S. Jude, whiche I translated at the requeste of one other my

deare frende.

These I did in Englishe the rather because at that tyme men ware not

so geuen all to Englishe, but that they dyd fauoure & maȳteine good

learning conteined in tongues & sciences, and did also study and apply

diligently the same thē selues. Therfore I thought no hurte done. Sence

y^t tyme diuerse other thynges I haue written, but with entente neuer

more to write in the Englishe tongue, partly because the cōmoditie of

that which is so written, passeth not the compasse of Englande, but

remaineth enclosed within the seas, and partly because I thought that

labours so taken should be halfe loste among them whiche sette not by

learnyng. Thirdly for that I thought it beste to auoide the iudgement

of the multitude, from whome in maters of learnyng a man shalbe forced

to dissente, in disprouyng that whiche they most approue, & approuyng

that whiche they moste disalowe. Fourthly for that the common settyng

furthe and printīg of euery foolishe thyng in englishe, both of

phisicke vnperfectly, and other matters vndiscretly diminishe the grace

of thynges learned set furth in thesame. But chiefely, because I wolde

geue none example or comforte to my countrie men, (whō I wolde to be

now, as here tofore they haue bene, comparable in learnyng to men of

other countries) to stonde onely in the Englishe tongue, but to leaue

the simplicite of thesame, and to procede further in many and diuerse

knoweleges bothe in tongues and sciences at home and in vniuersities,

to the adournyng of the cōmon welthe, better seruice of their kyng, &

great pleasure and commodite of their owne selues, to what kinde of

life so euer they shold applie them. Therfore whatsoeuer sence that

tyme I minded to write, I wrate y^e same either in greke or latine.

As firste of all certein commentaries vpon certein bokes of William

framinghā, maister of art in Cambrige, a man of great witte, memorie,

diligence and learnyng, brought vp in thesame scholes in Englande that

I was, euer frō his beginnyng vntil his death. Of the which bokes,

ij. of _cōtinētia_ (or cōtinence) wer in prose, y^e reste in metre

or verse of diuerse kindes. One a comforte for a blinde mā, entitled

_ad Aemilianum cæcum consolatio_, one other _Ecpyrosis, seu incendiū

sodomorū_, the burnyng of Sodome. The thirde _Laurentius_, expressyng

the tormentes of Saincte Laurence. The fourthe, _Idololatria_,

Idolatrie, not after the trade and veine of scripture (wherein he

was also very well exercised) but conformable to scripture and after

the ciuile and humane learnyng, declaryng them to worshippe _Mars_,

that warre, or fight: _Venus_, that lyue incontinently: _Pluto_, that

folowe riches couetousely; and so forth through all vices vsed in his

time. The fineth boke _Arete_, vertue: the sixth, Epigrāmes, conteined

in two bokes, whiche by an epistle of his owne hand before y^e boke

yet remainyng, he dedicated vnto me, purposyng to haue done many more

prety thynges, but that cruell death preuēted, and toke him away wher

he and I was borne at Norwiche, in the yere of our Lord M.d.xxxvij.

the xxix. daie of September, beynge then of the age of xxv. yeres,

vij. Monethes, and vj. daies, a greate losse of so notable a yonge

man. These workes at his death he willed to comme to my handes, by

which occasion after I had viewed thē, and perceiued them ful of al

kyndes of learnyng, thinkyng thē no workes for all mē to vnderstande

with out helpe, but such as were wel sene in all sortes of authours: I

endeuoured my selfe partely for the helpe of others, & partly for mine

owne exercise, to declare vpon theim the profite of my studie in ciuile

and humane learnynge, and to haue before mine eyes as in a worke (which

was alwaies my delyght) how muche I had profited in the same. Thys so

done, I ioyned euery of my commentaries to euery of hys saied bokes,

faier written by Nicolas Pergate puple to the saied Maister Framyngham,

myndyng after the iudgement of learned men had in thesame, to haue set

theim furthe in prynte, if it had ben so thought good to theim. For

whyche cause, at my departynge into Italie, I put an Epistle before

theym dedicatorye to the right Reuerend father in God Thomas Thirlbye,

now Bishoppe of Norwiche, because thesame maister Framyngham loued

hym aboue others. He after my departure deliuered the bokes to the

reuerende father in god Jhō Skippe, late bishop of Hereforde, then to

D. Thirtle, tutor to the sayd maister framynhā, frō him to syr Richard

Morisine, now ambassadoure for y^e kinges maiestie with thēperour, then

to D. Tailour Deane of Lincolne, and syr Thomas Smithe, secretarie

after to y^e kynges Maiestie, all great learned men. Frō these to

others they wente, among whome the bokes died, (as I suppose,) or els

be closely kept, that after my death they may be setfurthe in the names

of them which now haue thē, as their workes. Howe soeuer it be, wel I

knowe that at my returne out of Italie (after vj. yeres continuance

ther) into Englād, I coulde neuer vnderstand wher they wer, although I

bothe diligently and desirousely sought thē. After these I translated

out of Greke into Latine a litle boke of _Nicephorus_, declarynge howe

a man maye in praiynge confesse hym selfe, which after I dyd geue

vnto Jhō Grome bacheler in arte, a yong man in yeres, but in witte

& learnyng for his tyme, of great expectatiō. That done I beganne a

chronicle of the citie of Norwiche, of the beginninge therof & thinges

done ther frō time to time. The matere wherof yet rude and vndigested

lyeth by me, which at laisure I minde to polishe, and to make an

end of that I haue begunne. And to be shorte, in phisicke diuerse

thynges I haue made & settefurth in print bothe in Greke and Latine,

not mindyng to do other wise, as I haue before said, al my life: For

which cause al these thinges I haue rehersed, els superfluous in this

place. Yet see, meaning now to counseill a litle agaynst the sweatyng

sickenes for helpe also of others, notwithstandyng my former purpose,

two thynges compell me, in writynge therof, to returne agayne to

Englishe, Necessite of the matter, & good wyl to my countrie, frendes,

& acquaintance, whiche here to haue required me, to whome I thinke my

selfe borne.

Necessite, for that this disease is almoste peculiar vnto vs Englishe

men, and not common to all men, folowyng vs, as the shadowe the body,

in all countries, albeit not at al times. Therfore compelled I am to

vse this our Englishe tongue as best to be vnderstande, and moste

nedeful to whome it most foloweth, most behoueth to haue spedy remedie,

and often tymes leaste nyghe to places of succource and comforte at

lerned mennes handes: and leaste nedefull to be setfurthe in other

tongues to be vnderstand generally of all persons, whome it either

haunteth not at all, or els very seldome, as ones in an age. Thinkynge

it also better to write this in Englishe after mine own meanyng,

then to haue it translated out of my Latine by other after their

misunderstandyng.

Good wyll to my countrie frendes and acquaintance, seynge them wyth

out defence yelde vnto it, and it ferefully to inuade thē, furiousely

handle them, spedily oppresse them, vnmercyfully choke them, and that

in no small numbers, and such persons so notably noble in birthe,

goodly conditions, graue sobrietie, singular wisedōe, and great

learnynge, as Henry Duke of Suffolke, and the lorde Charles his

brother, as fewe hath bene sene lyke of their age: an heuy & pitifull

thyng to here or see. So that if by onely learned men in phisicke &

not this waye also it should be holpen, it were nedeful almost halfe

so many learned men to be redy in euery toune and citie, as their

should be sweatynge sicke folkes. Yet this notwithstandynge, I wyll

euery man not to refuse the counseill of the present or nighe physicen

learned, who maie, accordyng to the place, persone, cause, & other

circūstances, geue more particular counseil at nede, but in any wise

exhorte him to seke it with all diligence. To this enterprise also

amonge so many learned men, not a litle stirreth me the gentilnes and

good willes of al sortes of men, which I haue well proued heretofore by

my other former bokes. Mindynge therefore with as good a will to geue

my counseil in this, and trusting for no lesse gentlenes in the same, I

wyll plainly and in English for their better vnderstandynge to whome I

write, firste declare the beginnynge, name, nature, and signes of the

sweatynge sickenes. Next, the causes of the same. And thirdly, how to

preserue men frō it, and remedy them whē they haue it.

_The beginnyng of the disease._—In the yere of our Lorde God

M.CCCC.lxxxv. shortly after the vij. daye of august, at whiche tyme

kynge Henry the seuenth arriued at Milford in walles, out of Fraunce,

and in the firste yere of his reigne, ther chaunced a disease among

the people, lastyng the reste of that monethe & all september, which

for the soubdeine sharpenes and vnwont cruelnes passed the pestilence.

For this commonly geueth iij. or iiij. often vij. sumtyme ix. as that

firste at Athenes whiche _Thucidides_ describeth in his seconde boke,

sumtyme xj. and sumtyme xiiij. dayes respecte, to whome it vexeth.

But that immediatly killed some in opening theire windowes, some in

plaieng with children in their strete dores, some in one hour, many in

two it destroyed, & at the longest, to thē that merilye dined, it gaue

a sorowful Supper. As it founde them so it toke them, some in sleape

some in wake, some in mirthe some in care, some fasting & some ful,

some busy and some idle, and in one house sometyme three sometime fiue,

sometyme seuen sometyme eyght, sometyme more some tyme all, of the

whyche, if the haulfe in euerye Towne escaped, it was thoughte great

fauour. How, or wyth what maner it toke them, with what grieffe, and

accidentes it helde theym, herafter thē I wil declare, whē I shal come

to shewe the signes therof. In the mene space, know that this disease

(because it most did stand in sweating from the beginning vntil the

endyng) was called here, the Sweating sickenesse: and because it firste

beganne in Englande, it was named in other countries, the englishe

sweate. Yet some coniecture that it, or the like, hath bene before

seene among the Grekes in the siege of Troie. In thēperor Octauius

warres at _Cantabria_, called nowe Biscaie, in Hispaine: and in the

Turkes, at the Rhodes. How true that is, let the aucthours loke: how

true thys is, the best of our Chronicles shewith, & of the late begonne

disease the freshe memorie yet confirmeth. But if the name wer now to

be geuen, and at my libertie to make the same: I would of the maner and

space of the disease (by cause the same is no sweat only, as herafter

I will declare, & in the spirites) make the name _Ephemera_, which is

to sai, a feuer of one natural dai. A feuer, for the feruor or burning,

drieth & sweating feure like. Of one naturall day, for that it lasteth

but the time of xxiiij. houres. And for a distinction from the commune

_Ephemera_, that Galene writeth of, comming both of other causes,

and wyth vnlike paines, I wold putte to it either Englishe, for that

it followeth somoche English menne, to whō it is almoste proper, and

also began here: or els pestilent, for that it cōmeth by infection &

putrefaction, otherwise then doth the other _Ephemera_. Whiche thing I

suppose may the better be done, because I se straunge and no english

names both in Latine and Greke by commune vsage taken for Englishe.

As in Latin, Feure, Quotidiā, Tertian, Quartane, Aier, Infection,

Pestilence, Uomite, Person, Reines, Ueines, Peines, Chamere, Numbre,

&c. a litle altered by the commune pronunciation. In Greke, Pleuresie,

Ischiada, Hydrops, Apostema, Phlegma, and Chole: called by the vulgare

pronunciatiō, Schiatica, Dropsie, Impostume, Phleume, & Choler: Gyne

also, and Boutyre, Sciourel, Mouse, Rophe, Phrase, Paraphrase, & cephe,

wherof cometh Chaucers couercephe, in the romant of the Rose, writtē

and pronoūced comōly, kerchief in y^e south, & courchief in the north.

Thereof euery head or principall thing, is comonlye called cephe,

pronoūced & writtē, chief. Uery many other there be in our commune

tongue, whiche here to rehearse were to long. These for an example

shortelye I haue here noted. But for the name of this disease it maketh

now no matter, the name of Sweat beyng cōmōly vsed. Let vs therfore

returne to the thing, which as occasiō & cause serued, came againe in

the M.D.vi. the xxii. yeare of the said Kyng Henry the seuenth. Aftre

that, in the yeare M.D.xvii. the ix. yeare of Kyng Henry the viii,

and endured from July, vnto y^e middest of Decēbre. The iiii tyme, in

the yeare M.D.xxviii. the xx. yeare of thesaied Kyng, beginning in

thende of May, & continuing June and July. The fifth tyme of this

fearful _Ephemera_ of Englande, and pestilent sweat, is this in the

yeare M.D.LI. of oure Lorde GOD, and the fifth yeare of oure Souereigne

Lorde king Edwarde the sixth, beginning at Shrewesbury in the middest

of April, proceadinge with greate mortalitie to Ludlowe, Prestene, and

other places in Wales, then to Westchestre, Couentre, Drenfoorde, and

other tounes in the Southe, and suche as were in and aboute the way

to London, whether it came notablie the seuenth of July, and there

continuing sore, with the losse of vii. C. lxi. from the ix. day vntil

the xvi. daye, besides those that died in the vii. and viii. dayes, of

whō no registre was kept, frō that it abated vntil the xxx. day of the

same, with the losse of C. xlii. more. Then ceassing there, it wente

from thence throughe al the east partes of England into the Northe

vntill the ende of Auguste, at whiche tyme it diminished, and in the

ende of Septembre fully ceassed.

This disease is not a Sweat onely, (as it is thought & called) but a

feuer, as I saied, in the spirites by putrefaction venemous, with a

fight, trauaile, and laboure of nature againste the infection receyued

in the spirites, whervpon by chaunce foloweth a Sweate, or issueth an

humour compelled by nature, as also chanceth in other sicknesses whiche

consiste in humours, when they be in their state, and at the worste

in certein dayes iudicial, aswel by vomites, bledinges, & fluxes, as

by sweates. That this is true, the self sweates do shewe. For as in

vtter businesses, bodies yˆt sore do labour, by trauail of the same are

forced to sweat, so in inner diseases, the bodies traueiled & labored

by thē, are moued to the like. In which labors, if nature be strōg &

able to thrust out the poisō by sweat (not otherwise letted) yˆe persō

escapeth: if not, it dieth. That it is a feuer, thus I haue partly

declared, and more wil streight by the notes of the disease, vnder

one shewing also by thesame notes, signes, and short tariance of the

same, that it consisteth in the spirites. First by the peine in the

backe, or shoulder, peine in the extreme partes, as arme, or legge,

with a flusshing, or wind, as it semeth to certeine of the pacientes,

flieng in the same. Secondly by the grief in the liuer and the nigh

stomacke. Thirdely, by the peine in the head, & madnes of the same.

Fourthly by the passion of the hart. For the flusshing or wynde comming

in the vtter and extreame partes, is nothing els but the spirites of

those same gathered together, at the first entring of the euell aire,

agaynste the infection therof, and flyeng thesame from place to place,

for theire owne sauegarde. But at the last infected, they make a

grief where thei be forced, whiche cōmonly is in tharme or legge (the

fartheste partes of theire refuge) the backe or shulder: trieng ther

first a brūt as good souldiers, before they wil let their enemye come

further into theire dominion. The other grefes be therefore in thother

partes aforsaid & sorer, because the spirites be there most plētuous

as in their founteines, whether alwaies thinfection desireth to go.

For frō the liuer, the nigh stomack, braine, and harte, come all the

iij. sortes, and kyndes of spirites, the gouernoures of oure bodies,

as firste spronge there. But from the hart, the liuish spirites. In

putrifieng wherof by the euel aier in bodies fit for it, the harte is

oppressed. Wherupon also foloweth a marueilous heauinesse, (the fifthe

token of this disease,) and a desire to sleape, neuer contented, the

senses in al partes beynge as they were bounde or closed vp, the partes

therfore left heuy, vnliuishe, and dulle. Laste foloweth the shorte

abidinge, a certeine Token of the disease to be in the spirites, as wel

may be proued by the _Ephemera_ that Galene writethe of, whiche because

it consistethe in the Spirites, lasteth but one natural day. For as

fire in hardes or straw, is sone in flambe & sone oute, euen so heate

in the spirites, either by simple distemperature, or by infection and

putrefaction therin conceyued, is sone in flambe & sone out, and soner

for the vehemencye or greatnes of the same, whiche without lingering,

consumeth sone the light matter, contrary to al other diseases restyng

in humoures, wherin a fire ones kindeled, is not so sone put out, no

more then is the same in moiste woode, or fat Sea coles, as well by

the particular Example of the pestilence, (of al others most lyke

vnto this) may be declared, whyche by that it stādeth in euel humors,

tarieth as I said, sometyme, from iiij. vii. ix. & xj. vntill xiiij.

dayes, differentlie from this, by reason therof, albeit by infection

most lyke to this same. Thus vnder one laboure shortelie I haue

declared—both what this disease is, wherein it consisteth, howe and

with what accidentes it grieueth and is differente from the Pestilence,

and the propre signes, and tokens of the same, without the whiche,

if any do sweate, I take theym not to Sweate by this Sickenesse, but

rather by feare, heate of the yeare, many clothes, greate exercise,

affection, excesse in diete, or at the worst, by a smal cause of

infection, and less disposition of the bodi to this sicknes. So that,

insomoche as the body was nat al voide of matter, sweate it did when

infection came: but in that the mattere was not greate, the same coulde

neyther be perilous nor paineful as in others, in whom was greater

cause.

_The causes._—Hetherto I haue shewed the beginning, name, nature, &

signes of this disease: nowe I will declare the causes, which be ij.:

infectiō, & impure spirites in bodies corrupt by repletiō. Infection,

by thaire receiuing euel qualities, distēpring not only y^e hete, but

the hole substāce therof, in putrifieng thesame, and that generally ij.

waies. By the time of the yere vnnatural, & by the nature & site of the

soile & region—wherunto maye be put the particular accidentes of this

same. By the time of the yeare vnnaturall, as if winter be hot & drie,

somer hot and moist: (a fit time for sweates) the spring colde and

drye, the fall hot & moist. To this mai be ioyned the euel disposition

by constellation, whiche hath a great power & dominion in al erthly

thinges. By the site & nature of the soile & regiō, many wayes. First

& specially by euel mistes & exhalatiōs drawen out of the grounde

by the sūne in the heate of the yeare, as chanced amōg the Grekes in

the siege of Troy, wherby died firste dogges & mules, after, mē in

great numbre: & here also in Englād in this m.d.lj. yeare, the cause

of this pestilent sweate, but of dyuers nature. Whiche miste in the

countrie wher it began, was sene flie frō toune to toune, with suche

a stincke in morninges & eueninges, that mē could scarcely abide it.

Thē by dampes out of the earth, as out of Galenes _Barathrū_, or the

poetes _auernū_, or _aornū_, the dampes wherof be such, that thei kil

y^e birdes fliēg ouer them. Of like dampes, I heard in the north coūtry

in cole pits, wherby the laboring mē be straight killed, except before

the houre of coming therof (which thei know by y^e flame of their

cādle) thei auoid the groūd. Thirdly by putrefactiō or rot in groūdes

aftre great flouddes, in carions, & in dead men. After great fluddes,

as happened in y^e time of Gallien thēperor at rome, in _Achaia_ &

_Libia_, wher the seas sodeinly did ouerflow y^e cities nigh to y^t

same. And in the xi. yeare of _Pelagius_, when al the flouddes throughe

al Italye didde rage, but chieflye _Tibris_ at Rome, whiche in many

places was as highe as the walles of the citie.

In cariōs or dead bodies, as fortuned here in Englande vpon the sea

banckes in the tyme of King Alured, or Alfrede; (as some Chroniclers

write) but in the time of king Ethelred after Sabellicus, by occasion

of drowned Locustes cast vp by the Sea, which by a wynde were driuen

oute of Fraunce thether. This locust is a flie in bignes of a mānes

thumbe, in colour broune, in shape somewhat like a greshopper, hauing

vi. fiete, so many wynges, two tiethe, & an hedde like a horse, and

therfore called in Italy _Caualleto_, where ouer y^e city of _Padoa_,

in the yeare m.d.xiij. (as I remembre,) I, with manye more did see a

swarme of theim, whose passage ouer the citie, did laste two hours,

in breadth inestimable to euery man there. Here by example to note

infection by deadde menne in Warres, either in rotting aboue the

ground, as chaunced in Athenes by theim of Ethiopia, or els in beyng

buried ouerly as happened at Bulloigne, in the yere M.D.xlv. the

yeare aftre king Henrye theight had conquered the same, or by long

continuance of an hoste in one place, it is more playne by dayly

experience, then it neadeth to be shewed. Therefore I wil now go to

the fourth especial cause of infectiō, the pent aier, breaking out of

the ground in yearthquakes, as chaunced at Uenice in the first yeare

of _Andrea Dandulo_, then Duke, the xxiiij. day of Januarye, and xx.

hour after their computacion. By which infectiō mani died, & many were

borne before their time. The v. cause is close, & vnstirred aire, &

therfore putrified or corrupt, out of old welles, holes in y^e groūd

made for grain, wherof many I did se in & about _Pesaro_ in Italy, by

openīg thē aftre a great space, as both those coūtrimē do cōfesse, &

also by exāple is declared, for y^e manye in openīg thē vnwarely be

killed. Out of caues, & tōbes also, as chaūced first in the country of

_Babilonia_, proceding aftre into Grece, and so to Rome, by occasion

that y^e souldiers of themperour _Marcus Antoninus_, vpon hope of

money, brake up a golden coffine of _Auidius Cassius_, spiēg a litle

hole therin, in the tēple of _Apollo_ in _Seleucia_, as _Ammianus

Marcellinus_ writeth. To these mai be ioyned the particular causes of

infectiō, which I cal the accidentes of the place, augmenting thesame.

As nigh to dwelling places, merishe & muddy groundes, puddles or

donghilles, sinkes or canales, easing places or carions, deadde ditches

or rotten groundes, close aier in houses or ualleis, with suche like.

Thus muche for the firste cause.

The second cause of this Englyshe _Ephemera_, I said were thimpure

spirites in bodies corupt by repletiō. Repletion I cal here, abundance

of humores euel & maliciouse, from long time by litle & litle gathered

by euel diete, remaining in the bodye, coming either by to moche

meate, or by euel meate in qualitie, as infected frutes, meates of

euel iuse or nutrimēt; or both ioyntly. To such spirites when the aire

infectiue cometh cōsonant, thē be thei distēpered, corrupted, sore

handled; & oppressed, thē nature is forced, & the disease engendred.

But while I doe declare these impure spirites to be one cause, I must

remoue your myndes frō spirites to humours, for that the spirites

be fedde of the finest partes therof, & aftre bringe you againe to

spirites where I toke you. And forsomuche as I haue not yet forgotten

to whome I write, in this declaration I will leaue a part al learned

& subtil reasōs, as here void & vnmiete, & only vse suche as be most

euident to whom I write, & easiest to be vnderstanden of the same:

and at ones therwith shew also why it haūteth vs English men more thē

other nations. Therfore I passe ouer the vngētle sauoure or smell of

the sweate, grosenes, colour, and other qualities of the same, the

quantitie, the daunger in stopping, the maner in coming furthe redily,

or hardly, hot or cold, the notes in the excremētes, the state longer

or sorer, with suche others, which mai be tokēs of corrupt humours &

spirites, & onli wil stād upō iii. reasōs declaring y^e same swet by

gret repletiō to be in vs not otherwise for al the euel aire apt to

this disease, more thē other natiōs. For as hereaftre I wil shew, &

Galē cōfirmeth, our bodies cā not suffre any thīg or hurt by corrupt

& infectiue causes, except ther be in thē a certeī mater prepared apt

& like to receiue it, els if one were sick, al shuld be sick, if in

this countri, in al coūtres wher the infection came, which thīg we

se doth not chāce. For touching the first reasō, we se this sweting

sicknes or pestilēt _Ephemera_, to be oft in Englād, but neuer entreth

Scotland, (except the borders) albeit thei both be ioinctly within

the cōpas of on sea. The same begining here, hath assailed Brabant &

the costes nigh to it, but neuer, passed Germany, where ones it was

in like faciō as here, with great mortalitie, in the yere m.d.xxix.

Cause wherof none other there is naturall, then the euell diet of

these thre contries whiche destroy more meates and drynckes withoute

al ordre, cōueniēt time, reasō, or necessite, thē either Scotlande,

or all other countries vnder the sunne, to the greate annoiance of

their owne bodies and wittes, hinderance of theim which have nede,

and great dearth and scarcitie in their cōmon welthes. Wherfore if

_Esculapius_ the inuentour of phisike, y^e sauer of mē from death, and

restorer to life, should returne again īto this world, he could not

saue these sortes of men, hauing so moche sweatyng stuffe, so many

euill humoures laid vp in store, frō this displeasante, feareful, &

pestilent disease: except thei would learne a new lesson, & folowe a

new trade. For other wise, neither the auoidyng of this countrie (the

seconde reason) nor fleyng into others, (a commune refuge in other

diseases) wyll preserue vs Englishe men, as in this laste sweate is by

experience well proued in Cales, Antwerpe, and other places of Brabant,

wher only our contrimen ware sicke, & none others, except one or ii.

others of thenglishe diete, which is also to be noted. The cause hereof

natural is onely this, that they caried ouer with thē, & by lyke diete

ther incresed that whiche was the cause of their disease. Wherefore

lette vs asserteine our selues, that in what soeuer contrie lyke cause

and matter is, there commyng like aier and cause efficient, wil make

lyke effecte and disease in persōs of agreable complexions, age, and

diete, if the tyme also doe serue to these same, and in none others.

These I putte, for that the tyme of the yere hote, makethe moche to

the malice of the disease, in openynge the pores of the body, lettynge

in the euill aier, resoluynge the humores and makynge them flowable,

and disposing therfore the spirites accordyngly, besyde, that (as I

shewed in the first cause of this pestilente sweate) it stirreth and

draweth out of the erthe euill exhalations and mistes, to thinfection

of the aier and displeasure of vs. Diet I put, for that they of the

contrarie diete be not troubled with it at all. Age and complexion,

for this, that although it spareth nō age of bothe kyndes, nor no

complexion but some it touchethe, yet for the most parte (wherby rules

and reasones be alwayes to be made) it vexed theim of the middle age,

beste luste, and theim not moch vnder that, and of complexions hote &

moiste, as fitteste by their naughty & moche subtiltie of blode to fede

the spirites: or nigh and lyke to thesame in some one of the qualities,

as cholerike in hete, phlegmatike in moister, excepte thother their

qualities, as drinesse in cholerike, & cold in phlegmatike, by great

dominion ouer thother, did lette. For the clene contrarie complexiōs

to the infected aier, alwaies remaine helthful, saulfe and better then

tofore, the corrupte and infected aier notwithstandyng. Therfore cold

and drie persones either it touched not at all, or very fewe, and that

wyth no danger: such I say as beside their complexion, (whiche is so

harde to finde in any man exacte and simple, as exacte helthes) were

annoied with some corrupt humoures & spirites, and therfore mete by so

moch to receiue it, & that by good reasō. For nothing can naturally

haue power to do ought against any thing, excepte the same haue in

it selfe a disposicion by like qualities to receiue it. As the cause

in the fote cānot trouble the flanke and leue the knee (the mean

betwixte) except there were a greater consent and likenes of nature in

sufferance (whiche we call _sympathian_) betwixte those then thother.

Nor fire refusynge stones, canne burne hardes, strawe, stickes and

charcole, oile, waxe, fatte, and seacole, except these same first of

al wer apte, and by conuenient qualities disposed to be enflamed and

burned. Nor any man goeth about to burne water, because the qualities

thereof be contrary, and the body vndisposed to the like of fire. By

whiche reason it may also be perceiued, that y^e venemouse qualitie

of this corrupt aire is hote and moiste, for it redily enfectethe the

lyke complexions, and those nigh vnto theim, and the contrary not

at all, or hardly: & easely doth putrify, as doe the Southe wyndes.

Therfore next vnto those colde and drie cōplexions, olde men escaped

free, as like to theim by age: and children, as voide of replecion

consumed by their great hete, and therefore alwaies redy to eate. But

in this disease the subtile humour euill and abundant in full bodies

fedyng y^e spirites, is more to be noted then the humour complexional,

whiche notwithstanding, as an helper or hinderer to y^e same, is not

to be neglected. For els it should be in all contries and persones

indifferently, wher all complexiones be. The thirde and laste reason

is, y^t they which had thys sweat sore with perille or death, were

either men of welthe, ease, & welfare, or of the poorer sorte such as

wer idle persones, good ale drinkers, and Tauerne haunters. For these,

by y^e great welfare of the one sorte, and large drinkyng of thother,

heped vp in their bodies moche euill matter: by their ease and idlenes,

coulde not waste and consume it. A comfirmacion of this is, that the

laborouse and thinne dieted people, either had it not, because they dyd

eate but litle to make the matter: or with no greate grefe and danger,

because they laboured out moche thereof. Wherefore vpon small cause,

necessarily must folowe a smal effecte. All these reasones go to this

ende, that persones of all contries of moderate and good diete, escape

thys Englishe _Ephemera_, and those be onely vexed therewith, whiche

be of immoderate and euill diete. But why? for the euill humores and

corrupte aier alone? No, for thē the pestilence and not the swet should

rise. For what then? For y^e impure spirites corrupte in theim selues

and by the infectiue aier. Why so? for that of impure and corrupte

humores, whether thei be blode or others, can rise none other then

impure spirites. For euery thynge is suche as that whereof it commeth.

Now, that of the beste and fineste of the blode, yea in corrupte bodies

(whyche beste is nought) these spirites be ingendred and fedde, I

before expressed. Therfor who wyl haue them pure and cleane, and him

selfe free from sweat, muste kepe a pure and cleane diete, and then he

shalbe sure.

The Epidemics of the Middle Ages · 第 7 / 8 章