PART IX (SOLIDUNGULA).

It will naturally be expected that I should give a full account of

the parasites of the solipedal, solidungulate, or equine mammals. As

regards the horse I regret that I cannot meet this expectation in so

complete a manner as the subject deserves; nevertheless, with the aid of

an extended bibliography the summary here offered will be found to be

tolerably exhaustive. At all events I think I may say that no similar

record has hitherto been attempted.

The liver fluke (_Fasciola hepatica_), though not very frequent in

the horse, is not uncommon in the ass. In dissecting-room subjects

at the Royal Veterinary College it is often encountered. In France

it was originally found in the horse by Daubenton. As I learn from

Sonsino, Dr. Abbate Bey recently recorded a similar find at Cairo. In

solipeds generally the liver fluke appears to be almost harmless, for,

notwithstanding the frightful ravages produced by rot amongst a variety

of animals besides sheep, we have no evidence of the destruction of

horses from this cause. In the German outbreak of 1663-65 multitudes of

cattle and deer perished, and in the French outbreak of 1829-30 five

thousand horned beasts succumbed in the arrondissement of Montmédy

alone. In neither of these epizoötics were the solipeds affected. More

importance attaches itself to the study of the amphistomatoid flukes.

These parasites, though in a scientific sense only recently discovered

in equine bearers, have been long known to the natives of India. They

appear to be capable of producing serious intestinal irritation. I

have described two forms (_Amphistoma Collinsii_ and _A. Coll._, var.

_Stanleyi_), which infest the colon. The specimens sent to Prof. Simonds

from India by Mr Stanley, V.S., were much larger than those sent to me

from Simla by Mr Collins, V.S., some ten years later (1875). As in all

other amphistomes obtained from the intestines of elephants and cattle,

the worms, when fresh, were of a bright brick-red color. By the natives

of India these parasites are called _Masuri_; but no description of

the worms had been published prior to the account which I gave of the

contributions forwarded by Major-General Hawkes, Mr Collins, and Mr

Stanley.

I shall have occasion to speak of the elephant’s _Masuri_ further

on; but in the meantime I must remark that the generally received

notion as to the parasitic cause of the earth-eating propensities of

various animals seems to have some foundation in fact. Not alone from

Major-General Hawkes in Madras, from Mr Folkard in Ceylon, and from

various other trustworthy sources, have I been informed of this habit on

the part of Indian horses, but Dr Rowe told me that Australian horses,

and even sheep, infested with stomach-worms, are in the constant habit

of consuming large quantities of sand. From all the facts that have come

before me, I am inclined to think that gastric or intestinal irritation,

however brought about, may induce the habit in question, parasites being

only one of the many sources of irritation giving rise to symptoms

of colic in solipeds and pachyderms alike. At all events the African

elephants at the London Zoological Society’s Menagerie, as repeatedly

witnessed by myself, are in the habit of swallowing large quantities of

soft mud during the summer months, but no traces of _masuri_ have as yet

been detected in their fæces.

When by letter I informed Major-General Hawkes of an interesting find

by Mr Collins of _about a thousand_ Amphistomes in the colon of a horse

that had died at Simla, the announcement called forth a reply which

is sufficiently instructive to be quoted. Writing from Secunderabad

in July, 1875, he says, respecting this “find:”--“Your statement has

incidentally thrown light upon a subject which has puzzled many of

us in this country. It occasionally happens that a horse, on being

opened after death, is found to have accumulated in his intestines

large quantities of sand and gravel. In a recent case this accumulation

amounted to 14-1/2 lbs. Until recently it was always held that this

gravel or sand could only be introduced with the animal’s food. All

grain in this country is trodden out by bullocks on an earthen floor,

and the grain undoubtedly contains a proportion of sand and gravel

derived from this source. Although this _ought to be_ carefully washed

out before it is given to the horse, still, owing to the carelessness

of the native horse-keepers, this cleaning is, I expect, often omitted.

In the daily ‘feed’ of eight or ten pounds of grain given to each horse

the utmost quantity of sand or gravel that could be found admixed

therewith would not probably exceed two or three ounces; consequently

it would take from 77 to 116 days to accumulate so large a quantity

as 14-1/2 lbs. Now, the advocates of the theory of the gradual

accumulation of sand in this way have never been able to explain why

the grain, grass, hay, and other ingesta should pass in the ordinary

way through the intestines, whilst this sand or gravel remains behind.

One can understand the possibility of such substances as wool, hair, or

similar matters concreting in the alimentary canal, though I believe

they are usually found in the stomach, and not in the intestines; but

how a most incohesive substance like sand can possibly accumulate

in the gradual way required by their theory I have never heard even

plausibly explained. On the other hand, the fact that horses are often

excessively addicted to eating earth is well known; and if my memory

serves me correctly, it was found necessary, about twenty years ago, to

remove the mud-walls of the pickets surrounding some of the horses of

a mounted corps in this presidency in consequence of this habit. Now,

given the fact that the amphistoma has been found in the horse (as your

specimens prove), may we not fairly suppose it possible that the animal

resorts to the same mode of ridding himself of this parasite as does the

elephant? and also, would it not in a much more natural manner account

for the large quantity of gravel or sand found in the intestines than

does the theory of gradual accumulation? Reasoning from analogy, as

in the case of the elephant, this eating of earth in the horse would

be an instinctive effort on the part of the “host” to rid himself of

the parasite. This self-taken remedy is doubtless in many cases quite

effectual, _though unnoticed_. The fatal cases are probably those in

which the horse has either overdone the remedy or where the system was

too debilitated to carry off a quantity of sand or gravel that would

otherwise have safely passed through the intestines of a horse in more

robust health. The actual fact must, of course, be verified by careful

investigation.”

[Illustration: FIG. 62.--_Gastrodiscus Sonsinonis._ _a_, Mouth; _b_,

caudal sucker and posterior mesial cleft; _c_, left lip of the gastric

disk; _d_, anterior mesial cleft; _e_, e. gastric suckerlets; _f_,

reproductive papilla. Enlarged. Original.]

Closely allied to the Masuri is an amphistome which I originally named

_Gastrodiscus Sonsinoii_, but which should be altered as opposite

(Fig. 62). It exceeds 1/2″ in length and 1/3″ in breadth (16 mm. long

by 10 broad). Its discovery by Dr Sonsino was one of the results of

his examination of sixteen carcases of solipeds that died during the

Egyptian plague of 1876. Specimens having been forwarded to Panceri,

Von Siebold, Leuckart, and myself, most of us at once agreed that the

worm was new to science. Pointing to the genera, _Notocotylus_ and

_Aspidocotylus_, I explained its close affinity to the latter more

particularly. Whilst _Notocotylus_ has fifty supplementary suckers on

its back, _Aspidocotylus_ has nearly two hundred small ventral suckers

seated on a convex disk. In _Gastrodiscus_ a still larger number of

suckerlets are placed in the deep concavity of a large gastric disk

formed by the outstretched and inrolled margins of the body of the

parasite. Zoologically speaking, the odd thing about this singular

worm lies in the circumstance that its nearest fluke-relation, so

to speak (_Aspidocotylus mutablis_), dwells in a spiny-finned fish

(Cataphractus); and this fish itself forms an aberrant genus of the

family to which it belongs (Triglidæ). From what has been said it

will be seen that our _Gastrodiscus_ must not be confounded with

_Cotylegaster cochleariform_ (or with its synonym _Aspidogaster

cochleariformis_), to which parasite Von Siebold was, I believe,

induced to refer it. Like most of the true amphistomes, the worm in

question infests the intestines. Although discovered by Sonsino at

Zagazig in plague-affected corpses, there is no reason to suppose that

this helminth was in any way etiologically connected with the Egyptian

epizoöty.

The tapeworms of the horse are of great interest practically. Excluding

Sander’s _Tænia zebræ_, which was doubtless _T. plicata_, at least

five species have been described, but they may probably be all reduced

to two distinct forms and their varieties. Whilst _Tænia plicata_

acquires a length of three feet, the strobile of _T. perfoliata_ never

exceeds five inches. The lobes at the base of the head in the latter

are distinctive. The former is usually confined to the small intestine,

but the perfoliate worm often occupies the cæcum and colon in great

numbers. As regards _T. mamillana_, I may say that neither Gurlt’s

descriptions nor his figures are convincing. The worm is, I believe,

identical with _T. perfoliata_. In like manner, after going into the

matter with some care, I am accustomed to speak of Mégnin’s _T. inerme_

as _T. perfoliata_, var. _Mégnini_, and of Baillet’s _T. innomé_ as

_T. perfoliata_, var. _Bailletii_. I have examined great numbers of

equine tapeworms, but whether my determinations on this point are

correct or not, the case recorded by Mégnin is of remarkable interest.

Clinically, indeed, it is not entirely unique, since a somewhat similar

case has been recorded by Mr Poulton. In Mégnin’s equine patient the

autopsy revealed the presence of 200 bots, 153 lumbricoids, upwards of

400 oxyurides, and several thousand palisade worms, besides numerous

tapeworms. In Mr Poulton’s patient large quantities of tapeworms were

found in the duodenum (and in large sacs of the walls of other sections

of the small intestine), and also myriads of the little four-spined

strongyle, in addition to about a score of palisade worms. Both Mégnin’s

and Poulton’s patients died suddenly; but the great interest attaching

to Mégnin’s case arises from the boldness of manner in which the

French _savant_ interprets the phenomena of the intestinal sacculation

in relation to the development of the tapeworms. M. Mégnin assumes

that the sacs are due to the formation of polycephalous or cœnuroid

scolices. Without contradicting Mégnin’s ingenious interpretation of

the phenomena in question, I may say that the difficulty I have in

accepting his view arises from the circumstance of the rarity of the

occurrence of these sacs. In Poulton’s case of _Tænia perfoliata_, the

sacs were present, and they were productive of similar results; but

in the scores of other recorded cases of sudden death from the same

species of tapeworm (as published by Mr Rees Lloyd, and myself), the

presence of such sac-formations is not once mentioned. To be sure,

their presence may have been overlooked, but this is scarcely likely,

seeing the great care taken by Mr Lloyd in conducting the autopsies.

I cannot dwell upon the subject at greater length. The presence of so

many sexually-immature strobiles, combined with the existence of the

intestinal wall sacs, certainly does seem to point to the existence of

cœnuroid bladder-worms, but until the existence of the polycephalous

scolex be actually demonstrated one must be cautious in concluding “that

the horse nourishes at the same time the strobila and scolex of the

unarmed tapeworm.” Practically, we now know for certain that not only

are tapeworms capable of producing a fatal issue in isolated cases,

such as those recorded by Mégnin and Poulton, but that they may also be

productive of disastrous epizoöty, as proved by Mr Lloyd in the case of

Welsh mountain ponies.

In this connection I may perhaps be pardoned for saying that this

discovery in 1875 was one of the practical results directly issuing

from the publication of my ‘Manual’ in 1874. The attention of the

veterinary profession having been called to the subject of parasitic

epizoöty, Mr Lloyd was the first to make search for helminths amongst

some few of the carcases of the hundred and more equine animals that

perished in South Wales. Two totally distinct epizoötics prevailed. In

the Beacons district tapeworms alone were the cause of death, whilst

in the Deangunid district scores of animals perished from strongyles.

In another district a hundred animals perished from tapeworms. These

parasites I identified as examples of _Strongylus tetracanthus_ and

_Tænia perfoliata_. Taking all the helminthological facts together

we have made a great advance both in hippopathology and equine

epidemiology; and, as I observed at the time, the scepticism which not

unnaturally still exists (in reference to entozoa as a frequent cause of

death amongst animals, both wild and domesticated) will sooner or later

be dispersed by that wider attention to the subject which our labors

have invoked.

In relation to equine disease the facts brought forward are too

important to be dismissed in a single paragraph. As two distinct kinds

of parasitic epizoöty were discovered, the circumstances connected with

their separate detection must be noticed at greater length. Further

on, I shall again deal with the helminthiasis due to strongyles. It

was on the 17th of April, 1874, that I received from Mr Lloyd, of

Dowlais, Glamorganshire, a communication calling my attention to a

fatal epizoötic affecting ponies. He supposed the outbreak to be due

to parasites. On the following day I also received a parcel containing

portions of the lower intestines, which had been removed from one of the

diseased animals. The victim in question, a pony mare, had died on or

about the 12th of April, at Llangunider, Breconshire. Mr Lloyd states

in his letter that he “presumes” that the pony’s death was caused “by

the presence of small worms,” examples of which he now forwarded for

the purposes of identification and investigation. He also sent some

equine tapeworms. Mr Lloyd had already inferred that his small worms

were “strongyles;” and in regard to the tapeworms he says:--“This

species of parasite has caused, or is supposed to have caused, the

death of at least one hundred mountain ponies.” The investigation

being immediately proceeded with, I may so far anticipate my record of

the results obtained as to state at once that the facts observed by

me confirmed Mr Lloyd’s suspicions--proving, beyond a doubt, that the

pony above mentioned had succumbed to injuries inflicted by myriads of

minute strongyles. Not only did I find the fæcal matter of the colon

loaded with mature strongyles, but the walls of the intestine were also

occupied with encysted and immature forms of the same nematode species.

To such an extent had infection taken place, that I was enabled to

count no less than thirty-nine strongyles within the space of the one

fourth of a square inch. All parts of the sections of the colon under

examination were almost equally invaded; so that, taking the average,

I am clearly within the mark in saying that every square inch of the

gut yielded at least one hundred parasites. The walls of the entire

colon must therefore have been occupied by tens of thousands of these

creatures, to say nothing of the scarcely less numerous examples lying

free or lodged within the fæcal contents of the bowel.

In a second and more extended communication, sent in reply to inquiries

as to the cestodes, Mr Lloyd (whose letter I have abridged) writes:--“I

regret that I cannot give you very full particulars respecting the

tapeworms. During the last twelve months mountain ponies grazing on

the lower districts of Breconshire, which comprise some of the highest

mountains in South Wales, have been dying in great numbers, from what

the farmers indefinitely term inflammation. From what I have seen and

heard, it appears that there are three causes of death, the tapeworm,

the small worms (which I presumed were a kind of strongyle), and

catarrhal disorders, such as have been common among horses of late.

By far the greater number of deaths (from what I can glean) have been

caused by the parasites. In the Ystradfellte or Penderin districts there

has been no investigation, although the disease has reigned there for a

longer period, about eighteen months, with (from what I have heard) a

larger number of deaths than elsewhere; so I shall let these remain for

the present, as I have not had an opportunity to see or hear anything

authentic about them. In the Talybont district the cause appears to

be the small worms (like those I sent). The owner of the animals said

that a month ago, when he went to look after his ponies, they were

appearing quite well, and looked as well as he could expect them at

this season, but he was astonished to find some of them a fortnight ago

looking very lean and wasting, and he thought that the weather was the

cause of it, yet resolved to see them oftener; the next time he saw

them one was dead, and knowing of the loss in the neighbourhood, and

fearing he would be a sufferer, he sought aid, applying to me. When I

arrived two days following two more were dead, and they presented an

emaciated appearance. The post-mortem examination revealed a healthy

condition of the whole of the intestines, save slight thickening of some

parts of the colon and rectum, which contained, enclosed in the mucous

membrane, in cysts or minute sacs, worms coiled upon themselves. Each

cyst, containing one worm, was best seen by transmitted light. The colon

was nearly full of fæcal matter, which contained thousands of parasites

scarcely visible. The largest were very few in number, not exceeding

an inch in length and barely one sixteenth in diameter at the middle

portion. They somewhat tapered at both ends. The cæcum was half full

of fluid fæces, containing no visible worms; the rectum, with fæces of

natural consistence, the examination of which revealed only two or three

evident worms; so that the examination of fæces of living animals giving

results like this would not assist the diagnosis, unless suspected.

Small intestines--these latter contained about a dozen bots, which

were nearly free, but had pierced to the muscular coat. I should think

they had participated in the disease. The right lung had been slightly

congested; nothing else abnormal to be seen. Possibly congestion of

lungs would arise from the distress when pained with worms, for the pony

was found on its back with its head in a thicket--it had not appeared to

have struggled--with its teeth firmly closed.

“Respecting the animals affected with Tænia, it is remarkable that, as

a rule, they are in fair condition. The average time they appear to be

troubled with the worms is two months, and the symptoms observed have

been many. They are at first seen to be unable to keep up with the

other ponies, extending the head and turning the upper lip up, rubbing

the quarters, staring coat, suddenly appearing distracted, seizing

turf in mouthfuls when being griped or pained, others running away as

fast as they can go, or rolling and kicking on the ground for five or

ten minutes, then walking away as if nothing had happened, if coming

down a slope quickly almost sure to fall headlong, easier caught, not

unfrequently coughing, groaning noise, appetite good, and, what is

peculiar in some of them, lameness of one of the hind limbs, mostly the

near hind leg, with slight knuckling over at fetlock.

“_Post-mortem appearance._--Abdominal viscera normal, save rectum,

which is in some places slightly congested; colon nearly full of fæces,

no worms; cæcum, in which worms are alone found, is nearly full of

fæcal matter of thicker consistence than usual, and nearly half made up

of worms; stomach half full of partly digested food; heart and lungs

healthy; Schneiderian membrane injected; mucous membrane of trachea and

part of larger bronchiæ of a more or less livid colour (which may be

owing to asphyxia); corner of tongue bitten off; mouth very close.

“Several animals were found at times lying dead together.

“Of the _Tænia_ as many as three or four ponies, which some hours

previous had been seen grazing unaffected, were found dead on the same

spot; and this to my own knowledge, one farmer having lost ten.

“Of the small worms I have been told by a farmer that in his district

one of his neighbours had lost twelve ponies.”

As I had partly misunderstood my informant’s original statement, Mr

Lloyd, in a third communication, repeated the evidence, emphatically

reminding me that “the ponies affected with tapeworms are in a district

six or seven miles distant from those affected with strongyles. Those

troubled with tapeworms are in good condition, as a rule, up to death;

they are noticed to be troubled generally for two months previous to

death, and may be seen at one hour grazing and apparently well, and dead

or dying the next hour. As many as four have been found dead at the same

spot. In this (the Beacons) district the tapeworms alone have been found

and not a single strongyle. In the Deangunid district strongyles only

have been found, such as I sent you. The ponies have been noticed ailing

for three or four weeks, becoming rapidly emaciated and dying from

exhaustion. In tapeworm-affected animals the cæcum is nearly half full

of these parasites. The animals thus affected are on the red sandstone

formation, whilst those affected with strongyles occur on the limestone

formation--the latter affording the drier situation.”

Being on the teaching staff of the Royal Veterinary College I was

particularly glad to have the authority of an experienced veterinary

practitioner to testify to the injuriousness of _Tænia perfoliata_ in

the horse. Over and over again I had pointed out to the members of my

class the desirability of examining the fæces of solipeds where obscure

symptoms of intestinal irritation existed. Not only so; at the request

of friends I wrote out prescriptions suitable for equine patients

suffering from tapeworm. I felt the more indebted to Mr Lloyd, inasmuch

as his practical views served to strengthen the propositions I had

advanced in connection with internal parasites as a frequent cause

of epizoötics. My views were criticised at the time with a vigour and

warmth well worthy of those who are afraid of advancing epidemiological

science too rapidly; but it seems that so far from my having overstepped

the bounds of moderation in this matter I had, in reality, been too

cautious. Certainly it can now no longer be said that “the symptoms

created by tapeworms in the horse are of little or no consequence.”

Here, therefore, I repeat, we have made a clear and rapid advance in

our knowledge of helminthic disease; and from the impulse thus given to

hippopathology it is only reasonable to look for still further advances

in veterinary medicine. By-and-by, the scepticism which not unnaturally

exists in reference to entozoa as a frequent cause of death amongst

animals, will be dispersed by even yet clearer enunciations regarding

the important part these parasites play in the destruction of our most

valuable creatures.

Apart from the question incidentally raised by Mégnin as to their origin

and mode of development, the presence of larval cestodes in horses

cannot be passed over. The common hydatid (_Echinococcus veterinorum_),

though not of frequent occurrence, is occasionally productive of fatal

consequences. Very interesting cases are recorded by Messrs Henderson

and Kirkman, aided by the valuable comments of Professor Varnell. Mr

Hutchinson observed an hydatid in a horse’s eye, and Mr Vincent noticed

lameness, as resulting from hydatids. But one of the most interesting

cases of hydatids in solipeds is that described by Professor Huxley,

from a zebra that died at the Zoological Gardens in 1852. As stated

in Huxley’s elaborate memoir (freely quoted in the first part of this

work), the liver was found to be “one mass of cysts, varying in size

from a child’s head downwards.” The zebra’s death was purely accidental,

as it broke its neck while at play in the paddock. The long bladder-worm

of the horse (_Cysticercus fistularia_) is entirely unknown to me, and,

as before suggested, may be a mere variety of the _C. tenuicollis_ of

ruminants. An authentic instance of the occurrence of the gid hydatid

(_Cœnurus cerebralis_) in the horse is recorded by Gurlt. Lastly,

in relation to the question of food, it is worthy of remark that

whilst beef, veal, pork, and even mutton, are apt to be measled, the

muscle-flesh of horses is not liable to be infested by Cysticerci. This

is a fact in favor of hippophagy.

The nematodes of solipeds are very numerous, and first in importance

must be placed the palisade worm (_Strongylus armatus_). This worm was

known to Ruysch (1721). The old naturalists recognised two varieties

(_major_ and _minor_). These we now know to be merely the final stages

of growth of one and the same entozoon; and in both stages the worm

inflicts severe injury upon the bearer, chiefly, however, whilst

wandering through the tissues. The palisade worm has acquired notoriety

principally on account of its causing verminous aneurism, nevertheless,

this pathological change is not, in itself, the most disastrous evil

produced by the worm. In the adult state the female reaches a length

of two inches, whilst the male rarely exceeds an inch and a half. The

posterior ray of the caudal membrane or hood of the male is three-cleft.

In both sexes the head is armed with numerous, closely-set, upright

denticles, presenting the appearance of the teeth of a circular saw

or trephine. The eggs are elliptical and somewhat constricted at the

centre, their contents forming embryos after expulsion from both

parent-worm and host. The larvæ are rhabditiform, changing their skin,

in moist earth, in about three weeks, at which time they part with

their long tails. According to Leuckart, they pass into the body of an

intermediate bearer before entering the stomach of the definitive or

equine host. From the alimentary canal they pass to the blood-vessels,

causing aneurism, and thence they seek to regain the intestinal canal,

where they arrive at sexual maturity. It is during their migratory

efforts that they give rise to dangerous symptoms in the bearer, not

unfrequently causing the death of young animals, especially yearlings.

In the adult state the worm is also dangerous to the bearer, as it

produces severe wounds by anchoring to the mucous membrane of the gut.

The proofs we possess as to the frequency of abdominal, especially

mesenteric, aneurism from this source are overwhelming. Prof.

Brüchmüller estimated the percentage of aneurismal horses, six years old

and upwards, at 91 per cent., and it is a matter of common observation

in veterinary dissecting rooms that verminous aneurism is rarely or

never absent in the ass. Professors Dick, Simonds, Pritchard, Williams,

and many other English and Scotch veterinarians of eminence, have all

borne testimony of this kind, and, for myself, I may say that one of the

earliest pathological appearances with which I became familiar, some

thirty years back, was that presented by mesenteric arterial disease of

the ass. In relation to fatal colics in the horse the study of verminous

aneurism is of the highest moment. On this subject Prof. Friedberger

has published some valuable lectures, in which, amongst other points,

he incidentally remarks upon the comparative freedom of military horses

from aneurism as compared with ordinary laboring horses. This arises

partly from the fact that the latter are not cared for to the same

extent, dietetically and otherwise; and, moreover, cavalry horses are,

as a rule, younger than ordinary working animals. Whilst Friedberger,

in his suggestive brochure, does ample justice to the writings of

his colleague, Dr Bollinger, it may be said, in like manner, that he

does not fail to recognise his great indebtedness to the researches

of Leuckart. So practically important, however, do I deem Bollinger’s

summary of the whole subject in relation to the hippopathological

aspects of parasitism, that I feel it desirable to record his

conclusions at full length. No professional man having any pretensions

to a knowledge of the veterinary art--or, for that matter, to parasitism

in relation to sanitation--should remain uninformed on this subject. Dr

Bollinger’s results are thus stated:

1. The worm aneurism of the visceral arteries of the horse, existing in

90 to 94 per cent. of adult horses, has a general correspondence with

the _aneurisma verum mixtum_ of man. It is, however, distinguishable

from the same by its seat, cause, character of its walls, contents, and

mode of termination. The worm-aneurism arises from a parasitism of the

palisade worm (_Strongylus armatus_), owing to an inflammatory affection

of the arterial walls which it causes, and which one may describe as a

recurrent traumatic endo-arteritis. This holds good for all the visceral

arteries, with the exception of the abdominal aorta, in which an

aneurism may arise from local increase of pressure.

2. The formation and further development of the aneurism is also

favored by the narrowing of the arterial calibre, which is caused by

the inflammatory swelling of its walls, and also by the contemporaneous

formation of a thrombus (clot), this latter still further supporting and

exciting the inflammation of the inner coat.

3. Whilst the causes above mentioned (and of these more particularly the

continued presence of the palisade worms and the plugging of the smaller

arteries by thrombi) favor the growth of the worm-aneurism, the small

size of the same, notwithstanding the years it has existed, is explained

by the considerable hypertrophy of the muscular layer, by the tough

fibrous capsule formed in many cases by the connective tissue of the

mesentery, and by the adhesion of the intestines to the perpendicular

and free-lying anterior mesenteric artery; in particular this last-named

circumstance does not allow of any very considerable shortening of

the mesenteric artery, which would necessarily be accompanied by

considerable dilatation of the arterial tube.

4. The favorite seat of the worm-aneurism is the trunk of the anterior

mesenteric artery, directly at its origin from the abdominal aorta. Most

frequently that part of the arterial trunk is dilated from which the

arteria ilea, cæcales, and colica inferior (_arteria ileo-cæco-colica_)

arise, less frequently the arteria colica superior at its origin, and

the arteries of the cæcum and colon in their course in the meso-cæcum

and meso-colon. The verminous aneurism also occurs in the cœliac artery

(Bauchschlagader), in the posterior mesenteric artery (Gekrös-arterie),

in the renal artery, and in the abdominal aorta. A horse is not

unfrequently afflicted with several aneurisms of this kind at one and

the same time. Thus in one case (described by Bollinger) there were six

of these aneurisms affecting the abdominal aorta and its branches in the

same horse. The verminous aneurism may occur from the sixth month of

life onwards, and with increasing age; the number of horses free from

such aneurisms becomes continually smaller.

5. The size of the aneurism varies between that of a pea and that of a

man’s head. The dilatation is, as a rule, equal on all sides, the form

being usually thumb-shaped or bottle-shaped, passing into that of a cone

or long oval figure. This general configuration is principally due to

the free and moveable situation of the anterior mesenteric artery.

6. In contrast to aneurisms in man, the walls of the worm-aneurism of

the horse are almost without exception indurated. In addition to the

mesenteric connective tissue, all the arterial coats, and especially the

_tunica media_, generally take part in this induration. The hypertrophy

of the media, which stands unique in respect of what is known of

arterial disease, forms a compensatory action of the arterial wall,

analogous to the muscular hypertrophy of the heart in valvular disease.

This change in the media points to the fact that in the development of

aneurism in man the early disturbance of the nutritive process in the

_tunica media_ is not a less essential factor than the degeneration of

the _tunica intima_.

The changes in the _intima_ are the least constant. They present all

stages of progressive and retrogressive metamorphosis, from simple

induration to ulceration and calcification. In the walls of the

verminous aneurism one not unfrequently finds all the pathological

changes exhibited by _atheroma_ in man. Calcification is a common form

of the retrograde process, and, in very rare cases, may pass on to the

formation of true bone.

7. In addition to the palisade worms, one almost constantly finds a

parietal thrombus contained in the aneurism. It covers the inner wall

either partially or completely, being in the latter case perforated

for arterial offshoots. This clot may occlude the artery, and it is

not unfrequently continued into the arterial branches (peripherally)

or into the aorta (centrally). Amongst the various changes that the

clot undergoes, organisation of its outermost layer and softening are

the most frequent. The constant occurrence of this clot is due to the

presence of the worms, to the inflammation, ulcerative and regressive

affection of the intima, and to the dilatation of the arterial tube.

8. The palisade worms are seldom absent from aneurisms of the horse.

Their not being present is merely an accidental circumstance. On the

average, nine palisade worms go to a verminous aneurism, and eleven in

the horse. The highest number of worms found in one horse reached 121.

Not unfrequently, also, palisade worms, or their coverings in the form

of larval skins, are found in the aneurismal walls. The immigration and

emigration of the palisade worms out of the intestine into the aneurism,

and the reverse, take place probably, as a rule, within the arterial

circulation. The path of the worm does not appear to be always the same,

inasmuch as they can also wander through the peritoneal cavity. The

worms found in the aneurismal walls are probably mostly only strayed

specimens.

9. From a comparative pathologico-anatomical point of view, the

developmental history of the aneurysma verminosum proves that a

circumscribed endo-arteritis can determine the formation of an aneurism.

10. Like the worm-aneurism itself, atheroma of the abdominal arteries

arises from a circumscribed acute and subacute endo-arteritis. The

histological changes in the secondary atheroma of horses are perfectly

analogous to those of the spontaneous atheroma of man. Idiopathic

atheroma, as seen in man, does not occur any more in the horse than in

the other domestic animals. Atheroma in the horse is always secondary.

To be sure, one observes an idiopathic chronic endo-arteritis in

many abdominal arteries of the horse, which, however, never exhibits

indications of atheromatous degeneration.

11. In consequence of its position the worm-aneurism of horses is not

open to physical examination, and on that account cannot be diagnosed

by physical signs; moreover, it offers no characteristic symptoms.

Its termination by rupture is extremely rare, the aneurisms of the

abdominal aorta being more disposed to rupture than those of the

anterior mesenteric artery. Of eighteen cases of known perforation,

fifteen opened into the peritoneal cavity, and three into the bowel. The

dangerous symptoms of the worm-aneurism are exclusively due to embolism

and thrombosis of the affected artery, arising from the parietal clot.

The latter becomes especially dangerous through its increasing size and

the softening which often accompanies it. The absorption and shrinking

of this parietal clot, be it organised or not, is materially assisted by

the high pressure to which it is exposed.

12. The very marked symptoms of vascular obstruction--the

sero-hæmorrhagic intestinal infarct--in embolism and thrombosis of the

mesenteric arteries are easily explained by paralysis of the muscular

coat of the intestine, by the absence or paucity of valves in the portal

vein, by the readiness with which meteorismus (or flatus) arises,

especially in herbivora, and by the loose consistence of the intestinal

walls or villi.

13. The occlusion of the intestinal arteries, especially that arising

suddenly, always has for its result a partial or complete paralysis

of the portion of bowel which they supply. The palsy of the intestine

causes the forward movement of the intestinal contents to cease, a

stoppage of the fæces, a hindrance to the discharge of fæces and

gas, and also that exceedingly dangerous formation of gas (within

the intestinal tract) which in the herbivora is so abnormal, both

quantitatively and qualitatively.

14. In embolism and thrombosis of the mesenteric arteries the symptoms

during life are entirely identical with those observed in the so-called

colic of horses, as has been determined by numerous observations. The

partial paralysis of the bowel, which is brought on by the embolism and

thrombosis of the mesenteric arteries, forms in great part the chief

and leading feature of the series of symptoms known as the “colic” of

horses. The palsy of the bowel which arises in this way may explain also

the frequent ruptures of the digestive canal and the greater number

of its changes in position. The latter are specially favored by the

structure of the abdominal viscera in the horse.

15. The old changes which one finds in the peripheral branches of the

anterior mesenteric artery, in the form of expired and partly absorbed

embolic and thrombolic processes (pigmentation, arterial and venous

thrombi), particularly in connection with those arteries which are seats

of the aneurism, decisively prove that the large majority of colics

resulting in recovery, so far as they do not depend upon known injuries,

are caused by paralysis of the bowel from embolism and thrombosis. The

sudden occurrence, course, and result of these kinds of colics also

testify to their embolic origin.

16. The œdematous, inflammatory, and hæmorrhagic processes that one

often finds described as the cause of death in colic, almost exclusively

depend on thrombosis and embolism of the mesenteric arteries, the cases

forming about 40 to 50 per cent. of all fatal colics.

17. The rapid course in fatal colics, as well as the preponderating

symptoms of dyspnœa in cases of recovery, is finally due to the

abnormal development of gas in the alimentary canal. In addition to

the diminution of the respiratory surface by the lofty position of

the diaphragm, a direct gas-poisoning (carbonic acid and sulphuretted

hydrogen) probably contributes to the intensity of the symptoms and the

rapid course by diffusion of the abnormally developed gas out of the

intestinal canal into the blood.

18. The variety of the anatomical derangements caused by embolism and

thrombosis of the intestinal arteries is faithfully mirrored by the

variety of the clinical symptoms and the different degrees in the

intensity and course of the colic.

19. Amongst every 100 horses afflicted with internal disease, 40 are

ill with colic. Among any hundred deceased horses 40 have perished from

colic, and among 100 colic patients 87 recover and 13 die. The figures

prove that neither amongst the epizoötic nor sporadic diseases of horses

is there any other affection which occurs so frequently, or claims

anything like so many victims. Like the frequency of the worm-aneurism,

the amount of disease and mortality increases with advancing age. The

etiology of the colic of horses finds in the thrombosis and embolism of

the mesenteric arteries, with the consequent paralysis of the bowel, an

all-sufficient explanation, whilst the causes of colic hitherto accepted

were for the most part insufficient.

20. In a great number of cases the thrombus of the worm-aneurism is

continued past the mouth of the anterior mesenteric artery, into

the lumen of the aorta, and, as such, is the exclusive cause of the

embolisms of the pelvic and crural arteries which bring about the

intermittent hobblings (the author says “intermitterenden Hinken,” not

“Hahnentritten,” the usual equivalent term for stringhalt). Considering

the excessive frequency of the thrombus being continued into the

aorta, it becomes highly probable that a great part of the diseases

and lameness of the posterior extremities (“Hüft und Kreuzlähme,

unsichtbarer Spath, &c.,” which may be rendered “sciatic and hip or

spinal lameness, obscure spavin, &c.”) are due to occlusion of the

arteries.

21. Owing to the fibrous thickening of the connective tissue of the root

of the anterior mesenteric round the aneurism, and to the considerable

size of the latter, disturbances of the innervation of the intestine,

(as well as) hindrances to the passage of the chyle, and irregularities

in the portal circulation may be created, which may well lie at the root

of many chronic disturbances of digestion in horses.

22. Considering the great losses and heavy social disadvantages that are

occasioned by the colic of horses to the horse-breeder, to agriculture,

and to the general welfare, it is of the highest importance to discover

means which should prevent the introduction of the embryos with the

food, and, as a consequence, the migration of the palisade worms into

the mesenteric arteries of the horse.

I wish it to be distinctly understood that the above summary is

translated from Bollinger (_Die Kolik_; s. 257). Instructive cases have

been recorded both at home and abroad. Prof. Varnell has remarked that

“foals and yearlings suffer more from parasites in the paddocks than

they do on adjoining farms where only a few animals are bred.” This is

explained by the relatively greater amount of egg-dispersion proceeding

from the infected brood-mares. It is quite evident that the lives of

many valuable animals are annually sacrificed by the neglect of hygienic

arrangements. The palisade worm is chiefly destructive to young animals,

and as Mr. Percivall has well remarked, these parasites are “commonly

the cause of lingering and hidden disease, terminating in death,”

without any suspicion on the part of the practitioner as to the nature

of the malady. Instructive cases of this form of helminthiasis are given

by Messrs Littler, Wyer, Harris, Meyrick, Litt, Percivall, Tindal,

Walters, Brett, Aitken, Mead, Clancy, Baird, Mercer, Wright, Seaman,

Hepburn, and others.

[Illustration: FIG. 63.--Larvæ of _Strongylus tetracanthus_. _a_, from

the walls of the intestine (natural size); _b_, the same (enlarged);

_x_, an injury; _c_, younger specimen (_in sitû_); _d_, the same

(enlarged). Original.]

Second only in clinical importance is the little four-spined strongyle

(_S. tetracanthus_). The sexes, often seen united, are nearly of equal

size, the largest females reaching nearly 3/4″. They infest the cæcum

and colon, and have been found in all varieties of the horse, ass, and

mule. The worm occurs in immense numbers and is a true blood-sucker.

Its presence occasions severe colic and other violent symptoms, often

proving fatal to the bearer. As already announced, in connection with

my account of the tapeworms of the horse, this little worm may produce

a virulent epidemic (epizoöty). In the sexually-immature state the

worm occupies the walls of the large intestine, where it gives rise to

congestion, ecchymosis, inflammation, and the formation of pus deposits.

The species is readily recognised by its bright red color, by the four

conical spines surrounding the mouth, by the two neck-bristles, and by

the long three-lobed hood of the male, the posterior three-cleft ray

having a rudimentary or fourth branch attached to its outer edge. In

some specimens sent to me by Mr Whitney, I found this supplementary

process fully twice as long as Schneider has represented it.

From the earliest times this entozoon has been confounded with the

palisade worm. Rudolphi and several of his successors, and also in

recent times Ercolani and Colin, regarded this worm as the progeny of

_Strongylus armatus_. During my earlier examinations I likewise fell

into the error of describing the immature worm as representing a new

species. The parasites described by me as Trichonemes (_T. arcuata_)

were identical with those which Prof. Dick had previously described as

“worms at different stages of growth,” in his MS. sent to Dr Knox, 1836.

Parasites of this kind were described by Dr Knox as “Animals similar

to _Trichina_;” by Diesing as the “Nematoideum equi caballi;” by Mr.

Littler as “Extremely small ascarides,” in a letter to Mr Varnell; by Mr

Varnell himself as “Entozoa in various stages of growth;” and by Prof.

Williams as “Entozoa from the intestinal walls,” in a letter to myself,

dated March 13th, 1873. In reference, however, to Mr Varnell’s account

of Mr Littler’s specimens I may observe that the appearances which he at

first merely described as “blood spots,” he afterwards characterised as

dark points “containing young worms in various stages of growth.”

As regards the course of development of this worm we have yet much to

learn. Although the worm is a frequent cause of epizoöty in this country

it appears to be but little known on the Continent. Krabbe makes no

mention of the helminthiasis set up by the four-spined strongyle, but he

points out that the young occupy the mucous membrane, in which situation

they lie coiled so as to present to the naked eye the appearance of

little dark spots (_Husdyrenes Indvoldsorme_, 1872, p. 17, ‘Aftryk. of

Tidsskr. for Vet.’). However, Leuckart’s account of the appearances

presented in a case brought under his notice is instructive. He

writes:--“I have hitherto had only a single opportunity of examining

the strongyle capsules in the intestinal membrane of the horse. Their

presence is limited to the cæcum and colon, but they are so abundant in

this situation that their numbers may be estimated by many hundreds. It

was thus likewise in the case in question, the investigation of which by

myself was rendered possible through the friendliness of Prof. Haubner

of Dresden. The capsules were of oval form, and glimmered through the

mucous membrane as opaque spots, mostly from one to three millimètres

in size. In several of these capsules nothing was found beyond a greasy

mass of a brownish color, which might readily be taken for a tuberculous

substance; but the greater number of them contained a coiled worm,

from three to six millimètres long, their breadth being 0·15 to 0·26

mm. (which is 1/166″ to 1/99″). They exhibited a highly colored stout

intestine, and a thick-walled oral capsule of 0·022 mm. in depth and

0·025 mm. in breadth. On the dorsal side two three-cornered chitinous

lamellæ arise from the shallow floor of the small oral capsule. The

cuticle, notwithstanding its firm structure, was still destitute of

annulations. The tail (0·15 to 0·18 mm. in length) was strongly marked

off from the rest of the body, being of a slender cylindrical form with

a rounded-off extremity. The development of the sexual apparatus had not

yet commenced. Notwithstanding the great differences of size presented

by the body, the structure of all examples was exactly the same to the

minutest particular, without exception. Also the smallest specimens,

which scarcely measured one millimètre, found in capsules of 0·3 mm.

in diameter, were distinguishable only by the absence of the oral cup,

whose position was represented by a slender and thickened chitinous

cylinder, as obtains in the earliest parasitic juvenile condition of

_Dochmius trigonocephalus_. The transformation to the form presenting

an oral cup occurs through a moulting, which is accomplished already in

examples of 1·5 mm. in diameter. Later, also, the worms cast their skins

in their capsules, without, however, changing the oral cup. In regard

to the final purpose of this metamorphosis, my investigations have left

me entirely in the lurch; nevertheless, I do not entertain the smallest

doubt that the worms which I have here described are the larval forms of

_Strongylus tetracanthus_.”

[Illustration: FIG. 64.--Fæcal cysts or pellets containing the larvæ of

_Strongylus tetracanthus_. Specimen (_a_) being enlarged (_b_) to show

the protruding head and tail (_c_) of the worm. Original.]

From numerous examinations I have satisfied myself that the worms after

escaping the walls of the intestine--and they may often be observed in

the very act of passing--re-enter the lumen of the bowel to undergo

another change of skin prior to acquiring the adult state. This they

accomplish by rolling themselves within the fæcal matter of the horse’s

intestine. The best examples I have seen of this phenomenon occurred

in a case for the clinical particulars of which I am indebted to Mr

Cawthron. Most interesting was it to notice these immature worms, each

coiled within a sort of cocoon, which Mr Cawthron termed a cyst. All

the forty little cocoons more or less resembled pills, the bright red

color of their contained worms strongly contrasting with the dark color

of the cocoons. They consisted of compressed _débris_, which under the

microscope showed many common forms of vegetable hairs and parenchyma,

besides raphides and chlorophyll-granules. Internally, there was a

cavity corresponding with the shape of the worm. In one instance I

noticed that the worm had nearly completed its ecdysis, a portion of

the old skin still remaining attached to the tail.

As already remarked, the evidence respecting the frequency and

destructiveness of this little worm in England is now quite

overwhelming. In a series of papers contributed to the ‘Veterinarian’

(too long for full quotation here), I have endeavoured to do justice

to the “finds” and observations of those members of the veterinary

profession who were good enough to supply me with valuable notes and

communications. In particular must my indebtedness to Mr Rees Lloyd

be acknowledged, for, as previously observed, he it was who first

recognised the parasitic character of the Welsh epizoötic outbreaks. In

the Deangunid and Talybont districts these strongyles proved terribly

fatal to mountain ponies. It appears that the owners of the animals,

as soon as they perceived anything amiss, at once disposed of them by

sale, evidently anticipating fatal results sooner or later. The facts

connected with some of the isolated cases brought under Mr Lloyd’s

care are especially interesting, as showing the virulence of the

symptoms set up. Thus on the 9th of Feb., 1875, some time after I had

identified the species from specimens he had sent me, Mr Lloyd writes

as follows:--“The last case I had was one which had been sold in this

way, and which had suffered now and then from colicky pains for the

space of about two months. The animal had been drenched with febrifuges

and rubbed with stimulating liniments about the throat. However, I

was sent for one evening, about an hour before the patient’s death. I

soon diagnosed the case as parasitic, and at the same time considered

it to be a hopeless one. I remained with it the whole of the time, of

which about forty-five minutes of the most acute pain was borne by the

trembling beast, which was leaping, rolling, and tossing itself about

with astonishing rapidity. The bulging eyes, gnashing teeth, foaming

mouth, and sharp peculiar hoarseness, were pitiable to behold; when

suddenly all was silent, he quietly rose to his feet, and nipped the

grass as if nought had troubled him. I then trotted him quietly up a few

yards of rising ground in the corner of the field, when he immediately

got down to rise no more. The next day I examined him, and found myriads

of the four-spined strongyles, a large number being encysted.” Mr Rees

Lloyd’s account of this case is so graphic that I have reproduced it

without abridgment. Speaking of another patient, a mare, he says,

“she had voided thousands of these parasites, and was in a frightfully

emaciated condition, but beyond a craving appetite there was little else

to be noticed.” Notwithstanding the few diagnostic indications afforded,

Mr Lloyd, being led by the history of the case to suspect worms, at

once examined the fæces, when he discovered thousands of these minute

nematodes. Clinically, these facts ought not to be lost sight of. In

addition to Mr Lloyd’s cases I have received valuable particulars of

others at the hands of Prof. Williams, Messrs Cawthron, A. Clarke, T.

Gerrard, D. M. Storrar, and J. W. Whitney.

Practically, it is important to inform the persons most interested that

an active “drench” may be serviceable in dislodging the free intestinal

worms, but the administration of purgatives must not be persevered in.

As in the somewhat parallel case of Trichinosis in the human subject,

the fatality of the disorder depends not upon the free and mature worms,

but upon the migrating and sexually-immature forms. All attempts by

means of active drugs to poison the entozoa, when once they have gained

access to the tissues (whether actually capsuled or not), are worse

than useless. By all means let the animals have a dose of aloes in the

first instance, followed by warm bran mashes; but thereafter let every

care be taken to support the patient’s strength. Especially should the

exhibition of turpentine be avoided. Without doubt the cause of this,

as of other similar epidemics, is primarily referable to atmospheric

conditions which favor the multiplication of parasites. As the practical

man cannot alter these climatal changes, he must do his best to check

the disorder by removing the victims to new localities; or, if the

animals must remain in infected districts, by supplying them with

various kinds of artificially prepared fodder, supplemented by carefully

filtered water. In this way, I believe, epidemics may be arrested,

but they cannot be stamped out altogether, except by the adoption of

measures which would be alike impracticable and unwarrantable.

Passing to the consideration of other intestinal nematodes, the next in

importance is the large lumbricoid (_Ascaris megalocephala_) found in

all solipeds, including the zebra. Whilst the male worms rarely exceed

seven inches in length, the females sometimes reach seventeen inches.

Science is indebted to Schneider for setting at rest all doubt as to

the specific distinctness of this worm. The far larger number of caudal

papillæ at once distinguishes it from the lumbricoid of man and the

hog. The equine Ascaris may occur in any part of the alimentary canal,

but the small gut forms its proper head-quarters. The entire course of

development of this worm has not been traced; nevertheless, Heller found

human lumbricoids measuring less than the eighth of an inch. It is not

likely that any intermediate host is necessary for the growth of the

larvæ, prior to their access to the definitive host. I have reared the

larvæ in impure water and in moist horse-dung, up to the size of 1/30

of an inch. They were then furnished with a completely-formed digestive

apparatus. Davaine kept the intra-chorional embryos alive in water for

five or six years. His experiments on rats, dogs, and on a cow, led

to no decisive results; but it is important to know that the eggs of

lumbricoids effectually resist dryness. According to Davaine, however,

embryonal development is thus arrested (except in _Ascaris tetraptera_

of the mouse).

Seeing how readily the most ordinary attention to cleanliness must

suffice to prevent lumbricoid helminthism, it is scandalous that so

many severe cases of disease from this source should ever and anon turn

up and be reported. In no properly conducted stable are these large

entozoa ever to be seen in any considerable numbers; for so long as

the water-supply is good and the fodder clean there is no possibility

of infection. A fertile source of infection, however, results from

allowing horses to drink at foul road-side ponds and from open waters

in the vicinity of stables and paddocks where foals are reared. Into

the clinical bearings of the subject I do not enter, but a host of

interesting records of lumbricoid disease may be found in veterinary

journals, both home and foreign. These have their counterpart in the

very similar cases recorded in the medical journals, and quoted by me in

the 34th bibliography of this work. From Sonsino’s report these worms

do not appear very common in Egypt, but the veterinary inspector, Dr

Zunhinett, had occasionally met with them. From Messrs W. Awde, J. B.

Wolstenholme, and other English veterinary surgeons, I have received

notes of interesting cases, but in this connection I can only further

refer to the published cases of Messrs Anderson, Boddington, Cartwright,

Harrison, Moir, and Wallis. The French cases, by M. Cambron and by

M. Véret, are particularly instructive. Many of the cases give fatal

results. In one fatal instance a pupil of mine counted over 1200 of

these worms, and in a similar fatal case Mr Lewis reports that he found

the small intestine literally crammed, some thousands of worms being

huddled together in large masses.

[Illustration: FIG. 65.--Head of _Oxyuris curvula_. Highly magnified.

After Busk.]

The next nematode of general interest is the pinworm (_Oxyuris

curvula_). Professional men often confound it with the palisade worm,

and it has even been mistaken for the rat-tail maggot (_Helophilus_).

The longest males measure 1-3/4″, and the females often beyond 4

inches. This worm infests the colon in great numbers, the species being

easily recognised by its long subulate tail. Like its much smaller

congener infesting man, this worm occasions severe local irritation,

clusters of the eggs often accumulating to form yellow incrustations

at the verge of the anus. Equine pinworms are vegetable feeders, and,

like human Oxyurides, are conveyed to the bearer in a direct manner.

No horse properly looked after can be infested by these worms. Local

washings and stable cleanliness being secured by an attentive groom, the

animals are safe. Prophylactic measures of this kind are all-powerful

against infection. Notwithstanding the ease, however, with which the

oxyuris disorder may both be prevented and cured, we find it prevails

extensively everywhere, alike in mankind and in solipeds. Dr Sonsino

found these parasites abundant in Egypt, some of the worms reaching

a length of nearly five inches (120 mm.). Mr Emmerson has given an

interesting account of the prejudicial effects of these entozoa in the

horses of Singapore.

One of the most remarkable equine parasites is that which I am in the

habit of calling the large-mouthed maw-worm (_Spiroptera megastoma_),

in contra-distinction to the small-mouthed species (_S. microstoma_).

In this country the worm has attracted little notice, but through the

kindness of Mr Spooner Hart, of Calcutta, and of Mr Percivall, of the

11th Hussars, stationed at Umballa, I have had abundant opportunities

of examining this entozoon and the singular pathological appearances

which it occasions. This parasite was first described by Rudolphi,

who says:--“Spiroptera capitis discreti ore magno nudo, cauda feminæ

rectiuscula acuta, mavis simpliciter spirali, corpusculis rotundis ad

basim penis styliformis.” The worm was afterwards observed by Schultze,

Chabert, and frequently also by Andral, but the best accounts of it are

those given by Gurlt, Valenciennes, and Dujardin. Schneider has likewise

done much to set at rest disputed points. Respecting the _Spiroptère du

Cheval_, Dujardin, writing in 1844, observes that “Rudolphi at first

studied this helminth from examples found in great number by Reckleben,

at Berlin, in tubercles of the stomach of two horses. Quite recently,

M. Valenciennes, at Paris, has found it frequently in tumours, from

twenty to forty millimètres in size, in the stomach of eleven horses

out of twenty-five that he had subjected to this kind of research.

These tumours, lodged between the mucous and muscular layers of the

digestive canal, are perforated by several holes traversing the mucous

membrane. They are divided internally by a number of folds into numerous

intercommunicating cavities, and sometimes filled with solid mucus and

very many spiropteras. It is from examples collected by M. Valenciennes

that I have been able to study the parasite.”

As regards the description of the worm, it is almost needless to say

that Dujardin’s account is minute and admirable in all respects. In

fact, no naturalist ever exceeded the Rennes _savant_ in carefulness

and accuracy of detail. An interesting point connected with these

stomach-worms lies in the circumstance that Gurlt recognised two

varieties, one of which he termed _Sp. meg._, var. _major_. It remained

for Schneider to show that the larger worms formed an altogether

distinct species, which he termed _Filaria microstoma_ (‘Monogr.,’ l.

c., 1866, s. 98). It was not unnatural that Rudolphi and his successors

should confound these two forms together, and it is also not a little

curious that the smaller of the two species has the larger mouth.

Practically, veterinarians will probably rest content to know that

whilst the _Spiroptera megastoma_ occupies tumours in the walls of the

stomach, the _S. microstoma_ is always to be found free in the cavity

of that organ. Any helminthologist who may chance to have read the

Ceylon Company’s report on the fatal epidemic affecting the mules

of the Mauritius in 1876 can scarcely fail to have observed that the

worm called _Ascaris vermicularis_ by Mr Bradshaw is none other than

our _Sp. megastoma_. The description of the tumours as “reticulated”

sufficiently explains their honeycomb-like appearance, but I think that

the expression “alveolar” would better convey their true pathological

character. Mr Spooner Hart compared these structures, which he terms

“abodes,” to mole-hills, but there is no good ground for supposing that

the wanderings of the parasites are in any sense comparable to the

burrowings of the mole. In like manner the expression “nidus,” employed

by Mr Bradshaw, though suggestive of their nest-like appearance, is

to some extent misleading, as it implies that the worms form a nide

or brood. Possibly, it may turn out that all the nematodes in each

tumour have been bred in the spot where they are found, but hitherto

they have only been seen in the adult state. Earlier stages of growth

should be diligently sought for. Widely dissimilar as the two maw-worms

are, it would not greatly surprise me to learn that _Sp. megastoma_

and _S. microstoma_ are dimorphic conditions of one and the same

entozoon. At all events, Ercolani’s determination of the relations

subsisting between _Ascaris inflexa_ and _A. vesicularis_ suggests a

possible analogy of this kind. I may mention that the male _Spiroptera

megastoma_ reaches nearly one third and the female one half of an inch

in length. A constriction separates the head from the body. The mouth is

surrounded by four thick horny lips, the dorso-ventral pair being the

larger. The tail of the male is spirally twisted, and furnished with

lateral bands supported by three or four ribs. It carries two curved

spicules of unequal size. There are five pairs of caudal papillæ, the

tail being bluntly pointed in both sexes. The vulva of the female is

placed about 1/7″ below the head. The eggs are linear or very narrow,

and furnished with thick shells. According to Sonsino, who found _Sp.

megastoma_ in five out of sixteen Egyptian horses, the verminiferous

growths are usually seated near the pyloric end of the stomach, as many

as four tumours occurring at one time. Neither Sonsino nor any other

observers already quoted appear to think that these morbid changes in

any way interfere with the healthy performance of the gastric functions.

However, I am of opinion that at least one recorded fatal case of

parasitism, producing rupture of the stomach, affords an instance,

however rare, of the injurious action of this entozoon. It is reported

under the signature of “Argus,” quoted below.

In this connection I may mention that in 1864 Prof. Axe observed some

small worms, scarcely visible to the naked eye, in the mucous membrane

of the stomach of a donkey, the same worms being subsequently observed

in three other donkeys brought to the dissecting room of the Royal

Veterinary College. From the examination of a drawing of one of the male

worms, executed by Prof. Simonds, I am led to believe that the parasites

are entirely new to science. The hood being well marked there can be no

doubt as to the strongyloid affinities of the worm. I therefore propose

to call the worm after its discoverer (_Strongylus Axei_).

In regard to _Sp. microstoma_, the males measure up to 2/3″, whilst

the females have a long diameter of 3/4″ or rather more (10‴). The

small-mouthed maw-worm lives free in the stomach, and, as Krabbe

observes, not unfrequently in very considerable numbers. It does not

appear to be capable of injuring the host.

One of the most interesting equine nematodes is the eye-worm. Most

veterinary writers speak of it as the _Filaria oculi_, but to

helminthologists it is better known by the more correct designation, _F.

papillosa_. Though commonly obtained from the eyeball and its tunics,

the worm infests various tissues and organs of the body, being found

in the thorax, abdomen, membranes of the brain, muscles, and cellular

tissues. It infests the ass and mule, and also horned ruminants. The

males attain a length of three inches and the females seven inches. The

head is broad, with a gaping mouth armed with a ring of chitine and two

prominent denticles. There are also two papillæ on the neck near the

middle line, besides sixteen caudal papillæ, eight on either side. The

tail of the male is spirally twisted, that of the female only slightly

curved. Notwithstanding the many opportunities afforded of examining

this parasite in the fresh state, very little is known respecting its

origin and course of development. Dr Manson, who found that the mouth

was armed with a five- or six-toothed oral saw, considers that the eye

is not a proper resting place for the parasite, and that when one

wandering worm comes across the track of another it follows it up from

sexual instinct, and thus several may be found together in one place.

The tracks are readily seen by the naked eye. Dr Sonsino speaks of it

as a “yellow line.” This Italian observer found the worm in twelve

out of the sixteen solipeds he examined during the plague. Each horse

showed from two to a dozen worms “in the peritoneal cavity, wandering

free on the serous lining, without causing any apparent mischief to

the membrane.” On one occasion Sonsino found the worm in the liver.

From the similarity of habit there can be little doubt that the cases

of guinea-worm (_F. medinensis_) recorded by Clarkson and others, as

occurring in the horse, were merely examples of _F. papillosa_. I think

so all the more because the lamented Fedschenko verbally expressed to me

his astonishment that I had in my introductory treatise (p. 387) spoken

of the Dracunculus as an equine parasite. I did so on the authority of

others. To the Rev. Horace Waller I am indebted for specimens of the

eye-worm brought from Assam, and to Mr Spooner Hart for others sent from

India. For examples occurring in England I am indebted to Mr Haydon

Leggett, who, in 1875, sent me three specimens extracted from the eye

of a five-year-old mare. Mr Steel has also given me an example of _F.

papillosa_ taken from the peritoneum of a donkey. Similar cases are

constantly occurring in the practice of veterinarians in Hindostan.

Highly interesting Indian cases are recorded by Kennedy, Molyneux,

Twining, and Breton, and in addition to these I may also particularise

those of Macnamara, C. Percivall, Hickman, Clarkson, Skeavington, and

Jeaffreson. The cases by Lee and Grellier also deserve attention.

Another species of thread-worm (_Filaria lacrymalis_) is occasionally

found in the horse between the lids and eyeball. It is a comparatively

small and harmless parasite, the males measuring 1/2″ in length and the

females 2/3″. It also infests the ox. Both the large and small eye-worms

are viviparous, and, not improbably, both of them are the means of

conveying embryonic Filariæ into the circulation. Be this as it may, we

owe to Dr Sonsino the discovery of hæmatozoa in an Egyptian horse. The

larval worm was provisionally named by him _Filaria sanguinis equi_.

The microscopic nematodes closely resemble the larvæ of _F. sanguinis

hominis_, but they are smaller. The horse from whose blood Dr Sonsino

obtained the minute worms was also found, by post-mortem examination,

to have been infested by _Filaria papillosa_, a circumstance which

naturally suggested a genetic relation between the larval and adult

parasites. Similar, if not the same, microscopic worms had been

previously discovered by Wedl, who primarily and independently regarded

them as embryos of _F. papillosa_. Another curious filaria-like entozoon

is the reticulated threadworm (_Onchocerca reticulata_). In England we

have no acquaintance with this singular parasite, but it appears to be

tolerably common in Italy. Excellent figures of it have been given by

Diesing. Both males and females are in the habit of coiling themselves

within the muscles, where they are found invested by a capsule of

connective tissue. When unrolled the sexes are found of equal size,

acquiring a length of 1-1/2″. The worm has a simple unarmed mouth, its

body being marked by a series of annulations formed of incompletely

anastomosing rings. It does not appear to possess any clinical

importance.

In connection with the equine nematodes I need only mention the

lung-worm (_Strongylus micrurus_). Its importance in relation to the

production of husk or parasitic bronchitis in calves has already been

considered. The worm is rarely productive of mischief amongst solipeds,

nevertheless, in the dissecting-room subjects at the Royal Veterinary

College, the presence of these parasites in the lungs is frequently

noticed. Lastly, it only remains for me to observe that the renal

strongyle (_S. gigas_) is occasionally seen in the horse. In 1792 M.

Chabert found one in the left kidney, and similar cases have since

either been witnessed or reported by Rudolphi and Leblanc.

Of the numerous insect parasites and tormentors of solipeds the gadflies

(_Œstridæ_) demand chief attention. For special description of the

forms, Brauer’s monograph is the most, and, in fact, the only reliable

authority. Here it is not possible to give the characters of the various

equine species, of which at least half a dozen are known to science. As

remarked by me in the special chapter contributed to Prof. Williams’

well-known veterinary treatise, the common gad-fly (_Gastrophilus equi_)

attacks the animal whilst grazing late in the summer, its object being,

not to derive sustenance, but to deposit its eggs. This it accomplishes

by means of a glutinous excretion, causing the ova to adhere to the

hairs. The parts selected are chiefly those of the shoulder, base of the

neck, and inner part of the fore legs, especially about the knees, for

in these situations the horse will have no difficulty in reaching the

ova with its tongue. When the animal licks those parts of the coat where

the eggs have been placed, the moisture of the tongue, aided by warmth,

hatches the ova, and in something less than three weeks from the time

of the deposition of the eggs, the larvæ make their escape. As maggots

they are next transferred to the mouth, and ultimately to the stomach

along with food and drink. A great many larvæ perish during this passive

mode of immigration, some being dropped from the mouth, and others being

crushed in the fodder during mastication. It has been calculated that

out of the many hundreds of eggs deposited on a single horse, scarcely

one out of fifty of the larvæ arrive within the stomach. Notwithstanding

this waste the interior of the stomach may become completely covered

with “bots.” Whether there be few or many, they are anchored in this

situation chiefly by means of two large cephalic hooks. After the bots

have attained perfect growth they voluntarily loosen their hold, and

allow themselves to be carried along the alimentary canal until they

escape with the fæces. Many persons suppose that during their passage

through the intestinal canal they re-attach themselves to the mucous

membrane, thereby occasioning severe intestinal irritation. This is an

error. In all cases they sooner or later fall to the ground, and when

transferred to the soil they bury themselves beneath the surface, in

order to undergo transformation into the pupa condition. Having remained

in the earth for a period of six or seven weeks they finally emerge

from their pupal-cocoons as perfect dipterous insects. It thus appears

that bots ordinarily pass about eight months of their lifetime in the

digestive organs of the horse.

That they are capable of giving rise to severe disease there can be no

doubt, but it is not often that the disorder is correctly diagnosed,

since it is only by the passage of the larvæ that the practitioner can

be made aware of their presence. Mr J. S. Wood has published a case of

tetanus in a mare, associated with the larvæ of _Œstrus equi_, and Mr

J. T. Brewer has also given a case where the duodenum was perforated

by bots. Mr Goodworth records an instance of pyloric obstruction from

the same cause, and Mr W. Coupe informed me in 1876 that he had a drove

of foreign ponies under his care, all of which suffered irritation

from hæmorrhoidal bots. He removed them with a pair of forceps.

Although frequently said to do so, the common bot does not attach

itself to the rectum before finally escaping the host. The larvæ of _G.

hæmorrhoidalis_ normally reside there. In this situation they seriously

inconvenience the bearer. The bots of _G. nasalis_ are often confounded

with those which ordinarily occupy the stomach of the bearer. The larvæ

of _G. nasalis_ commonly reside in the duodenum near the pylorus.

According to Schwab and Brauer, they rarely occupy the stomach. As

occurs in the common species, this bot passes away with the fæces, and

does not attach itself to the lower bowel. The bots of Brauer’s _G.

inermis_ much resemble those of _G. equi_, but they are much smaller

and attach themselves to the wall of the small intestine. The bots of

_G. pecorum_, which dwell in the rectum, are readily recognised by

their peculiar form and scanty spination. They are pointed in front

and truncated posteriorly. An assinine variety of _G. equi_ has been

described by Bilharz, whilst another distinct species (_G. flavipes_)

attacks the ass and mule. The bot-larvæ of the latter host require

recognition and description. A great variety of other equine bot-flies

have been described, but all, or nearly all, of them are mere synonyms

of the above-mentioned forms. For the limitation of the species I accept

Brauer’s authority, and likewise his nomenclature. A great deal of

nonsense has been written respecting bots. It is a relief to believe

that _G._ (Œstrus) _veterinus_, _G. ferruginatus_, _G. jubarum_, _G._

(Œ.) _Clarkii_, _G. salutiferus_, _G. subjacens_, and many others, are

not good species, at least that they are mere synonyms. In regard to

the occurrence of subcutaneous bot-like maggots in the horse and ass,

no doubt need exist on this point. I am indebted to Mr Percy Gregory

for characteristic specimens taken from the back, neck, and withers of

a four-year-old gelding. They appear to correspond with the _Hypoderma

Loiseti_ of Joly. Similar maggots have been found in the ass by Herr

Erber, but Brauer refers these to _H. silenus_. Prof. Brückmüller

published a case where the brain was infested by larvæ; and Mr Shipley

has sent me an example of _H. equi_, which he states he removed from

the choroid plexus of the brain. In addition to the cases by Woods,

Goodworth, and Brewer, already quoted, others have been published by

Tyndal and Cartwright.

Amongst the numerous other parasitic dipterous larvæ one must notice the

rat-tailed maggots (_Helophilus_). A genuine instance of this kind has

been brought under my observation, but the example recorded by Professor

Axe was spurious. Professor Simonds and myself saw this supposed maggot,

which was merely a very stout and pregnant _Oxyuris curvula_. Another

genuine case was published by Mr. Stanley. This is quoted by A. Numan in

his essay on _Cœnurus_. I have previously mentioned my having received

an Helophilus-larva that had passed from the human body. One of the

most troublesome external parasites is the so-called horse-tick or

forest-fly (_Hippobosca equina_). They attack the abdomen, flanks, and

inner part of the thighs in great numbers, occasioning great distress

to the bearer. Being of leathery toughness their bodies are not easily

crushed, and they are removed only with great difficulty. There is

an equine disease in Sweden called _Stackra_, which is erroneously

attributed to injuries produced by a species of fly-maggot (_Lixus_)

which lives on the fine-leaved water-drop wort (_Phellandrium_). As

regards the so-called free parasites, or rather non-parasitic obnoxious

insects, which torment solipeds, it is impossible even to enumerate

them. The tsetse of South Africa (_Glossina morsitans_) is terribly

fatal to the horse, but it is said that the mule, ass, and zebra

do not suffer from its bites--an immunity shared by swine, goats,

antelopes, and man himself. Major Vardon’s rash experiment (based on

the supposition that horses deprived of fresh green food would not

suffer from the attacks of the fly) proved fatal to an animal which he

purposely exposed on a much infested hill-top. The horse died ten days

after it was bitten. According to Chapman, the bites of four tsetse

flies are sufficient to kill an ox, but in man the irritation produced

is very slight. Amongst other insects proving troublesome to solipeds

may be mentioned the leg-sticker (_Stomoxys calcitrans_), the clegg

(_Hæmatopota pluvialis_) which is very abundant in the West Highlands,

various species of _Tabanidæ_ and _Asilidæ_ (_Tabanus autumnalis_, _T.

bovinus_, _Chrysops cæcutiens_, _Asilus crabroniformis_), and also a

host of ordinary flies and gnats (_Muscidæ_ and _Tipulidæ_), as, for

example, _Anthomyia meteorica_ and _Culex equinus_. In India the bite

of a species of _Simulia_ gives rise to the formation of open sores of

the most intractable character. As regards hemipterous insects it may

be said that many species of lice (_Anoplura_) produce what is called

phthiriasis or lousiness in the horse, some of them being derived

from poultry. The best known species are _Trichodectes equi_, _T.

scalaris_, _Hæmatopinus equi_, _H. vituli_, _H. eurysternus_, and the

ass-louse (_H. asini_). Of the half dozen or more species infesting the

hen (belonging to the genera _Goniocotes_, _Liotheum_, &c.) it is not

probable that more than one or, at most, two of them are concerned in

the production of poultry-lousiness in the horse. As an equine disorder

this kind of phthiriasis was first described by Bouley. Cases in England

have been observed by Messrs. Henderson, Moore, and Woodger. For some

account of cases of lousiness due to _Hæmatopinus_ I am indebted to

Mr S. Butters. As regards the scab, itch, and mange insects or mites

(_Acaridæ_), three perfectly distinct forms are known. Adopting M.

Mégnin’s classification they are _Sarcoptes scabiei_, var. _equi_,

_Psoroptes longirostris_, var. _equi_ (being the _Dermatodectes equi_

of Gerlach), and _Chorioptes spathiferus_, var. _equi_, which is the

_Symbiotes equi_ of Gerlach. All the species have been beautifully

illustrated by M. Mégnin, whose memoir has dispersed many of the

clouds of error and misrepresentation which have hitherto surrounded

the subject. Whilst _Psoroptes_ forms the true horse-mite, and attacks

various parts of the body, _Chorioptes_ confines its attacks to the

posterior regions. Messrs South and Day and myself have verified some

of the facts recorded by Mégnin in respect of the structure and habits

of this last species. Another kind of mite (_Glyciphagus hippopodos_)

is stated to infest the ulcerated feet of horses. It would appear that

no true ticks properly belong to solipeds; nevertheless, the common

cattle-tick (_Ixodes bovis_) occasionally attacks horses. Probably

several other species of Ixodidæ, known to infest other animals, behave

in the same way. The Arachnidan called _Pentastoma tænioides_, though

properly belonging to the dog, has on several occasions been detected in

the nasal or frontal sinuses of the horse. Such instances are recorded

by Chabert and Greve. The largest example of this singular entozoon seen

by myself was obtained from the same situation, and presented to me

by the late Mr C. B. Rose, whose writings I have frequently quoted in

connection with the _Cœnuri_ of rabbits.

BIBLIOGRAPHY (No. 50).--_Aitken, J._, “Worms in the Spermatic Artery

of a Colt,” ‘Veterinarian,’ p. 683, 1855.--_Anderson, J._, “A Case

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261, 1859.--(Anonymous), “Rupture of the Stomach, associated with the

existence of Cysts between its Coats containing Worms,” ‘Veterinarian,’

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the Horse,” by “Miles,” ‘Veterinarian,’ 1864, p. 218.--(Anon.), “Case

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der Eingeweidearterien,’ Munchen, 1870. (Reviewed by myself in the

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in a Sinuous Ulcer of the Withers of a Mare,” ‘Veterinarian,’ p. 515,

1861.--_Bradshaw, C._, “Death of Mules from Parasitic Disease in the

Mauritius (with remarks by Dr Cobbold),” ‘Veterinarian,’ Dec., 1876, p.

837.--_Brauer, F._, ‘Monographie der Œstriden,’ Wien, 1863.--_Idem_,

“_Œstr. (Hypoderma) Clarkii_,” in ‘Verhandl. der zool.-bot. Gessellsch.

in Wien,’ xxv, p. 75.--_Idem_, “On _Cephenomyia trompe_ from the

Reindeer,” _ibid._, p. 77.--_Idem_, “_Hypoderma bonassi_ from the

American Buffalo,” _ibid._ (all with figs.), 1875.--_Breton_, “On the

Worm found in the Eye of the Horse,” ‘Calcutta Med. and Phys. Soc.

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Horse-bot,” the ‘Veterinary Journal,’ July, 1877, p. 14.--_Brückmüller_,

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the Bowels, associated with about 150 Bots, and also some 150 Ascarides,

in the Horse,” ‘Veterinarian,’ p. 413, 1833.--_Idem_, “Case of about 200

‘Bots in the Œsophagus’ of a Horse,” _ibid._, p. 400, 1828.--_Chambron_,

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612.--_Clark, B._, “Obs. on the genus Œstrus,” ‘Linn. Trans.,’ vol.

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Animals,’ London, 1815.--_Clarkson, N. F._, “Case of _Filaria oculi_

in the Horse,” ‘Vet. Rec.,’ vol. i, p. 73, 1845.--_Idem_, “Case of

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Diptera (bots),” in a chap. on the Parasitic Diseases of Animals, in

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from the Horse,” ‘Veterinarian,’ Feb., 1874.--_Idem_, “Further remarks

on rare Parasites from the Horse,” _ibid._, April, 1874.--_Idem_,

“Fatal Epid. affecting Ponies,” _ibid._, June, 1874.--_Idem_, “Remarks

on Mégnin’s Tapeworm,” _ibid._, Sept., 1874.--_Idem_, “Report on

Parasites (sent from India by F. F. Collins and Spooner Hart),”

_ibid._, Nov., 1874.--_Idem_, “Epizoöty in the Horse, more especially

in relation to the Ravages produced by the Four-spined Strongyle (_S.

tetracanthus_),” _ibid._, April, 1875.--_Idem_, “The Egyptian Horse

Plague in relation to the question of Parasitism,” _ibid._, Nov.,

1876.--_Idem_, “Description of the new Equine Fluke (_Gastrodiscus

Sonsinoii_),” _ibid._, April, 1877.--_Idem_, “On Worm-like Organisms

within the Mitral Valve of a Horse,” _ibid._, 1877.--_Idem_, “Entozoa

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p. 37, in his ‘Observations, chiefly practical, on some of the more

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“Worm in the Eye of the Horse (two cases),” ‘Veterinarian,’ p. 75,

1828.--_Percivall, J._, “A Case of Ascarides in the large Intestines

of the Horse,” ‘Veterinarian,’ p. 358, 1829.--_Poulton, T. J._, “Large

numbers of Parasites in the Intestines of a Mare,” ‘Veterinarian,’

1866, p. 385.--_Seaman, J._, “Worms in the Blood-vessels of Horses and

Colts,” ‘Edin. Vet. Rev.,’ 1864, p. 520.--_Simonds_, “On Disease of

the Mesenteric Artery, produced by Strongyli,” ‘Path. Soc. Trans.,’

1854.--_Skeavington, G._, “On Worm in the Eye of the Horse (three

cases),” ‘Veterinarian,’ 1834, p. 196.--_Sonsino, P._, “On the

Entozoa of the Horse in relation to the late Egyptian Equine Plague,”

‘Veterinarian,’ Feb. and March, 1877.--_Tyndal, J._, “Worms in the

Intestines of a Mare,” ‘Veterinarian,’ 1843, p. 629.--_Twining, W._,

“Obs. on the Filaria or Threadworm found in the Eyes of Horses

in India,” ‘Calcutta Med. and Phys. Soc. Trans.,’ vol. i, p. 345,

1825; rep. in ‘Veterinarian,’ p. 114, 1828.--_Valenciennes_, “On the

_Spiroptera megastoma_ of Gurlt,” abstract of a paper from Acad. Sci.

of Paris, reported in ‘Lancet,’ 1843.--_Varnell_, “Remarks on Cases of

Parasitic Disease in Horses,” ‘Veterinarian,’ p. 201, 1864.--_Veret_,

“Perforation of the small Intestines by _Ascarides lumbricoides_ (in

the Horse),” from ‘Rec. de Méd. Vét.,’ in ‘Veterinarian,’ p. 569,

1837.--_Vincent_, “Curious case of Incurable Lameness from Hydatids,”

‘Veterinarian,’ 1848, p. 674; see also p. 3, _ibid._--_Wallis_, “Note

on the occurrence of (250) Lumbrici in a Horse,” ‘Veterinary Record,’

1849, p. 300.--_Walters, R. G._, “Parasites in the Kidneys of a Mare,”

‘Veterinarian,’ 1866, p. 265.--_Woodger_, “Hydatid in the Brain of a

Horse,” ‘Veterinarian,’ 1863, p. 75.--_Woods, J. S._, “Tetanus in a

Mare, associated with the Larvæ of _Œstrus equi_ within the Stomach

and Duodenum,” ‘Veterinarian,’ 1859, p. 693.--_Wright_, “Strongyli in

the Scrotum of a Colt,” ‘Veterinary Record,’ 1849, p. 385.--_Youatt_,

“Worms between the Tunics of the Stomach,” ‘Veterinarian,’ 1835, p.

571.--_Idem_, “Tetanus, Worms in the Trachea, and Dilatation of the

Heart, in a Zebra,” _ibid._, p. 504, 1836.--_Idem_, “Worms in the Nasal

Cavity of the Horse,” _ibid._, p. 329, 1832.--_Zangger_, “Remarks on

Entozoa,” from the French, ‘Veterinarian,’ 1855, p. 463.