I. _State of this System in the first age._

In the first periods of existence, the articular fibro-cartilages are

much developed, which appears to be the effect of the size of the

articulations at this period. In fact, as the extremities of the bones

are larger in proportion, whilst they are cartilaginous, than when they

are in the osseous state, the articulations are also proportionally

larger, and the organs they contain more developed.

The fibro-cartilages of the grooves, which are found almost all, as

we know, situated at the extremities of the long bones, are not, in

the first age distinct from the cartilages of ossification, which then

form these extremities. Confounded with them, they exhibit no line of

demarcation when we cut the lines at that place. This state continues

until complete ossification; then the fibro-cartilages of the grooves

remain insulated like the cartilages of the osseous extremities.

The interposed gelatinous portion appears to predominate, in childhood,

over the fibrous portion in the articular fibro-cartilages and in those

of the grooves. It is remarkable in the intervertebral substances,

in which this kind of mucilage which occupies the centre, is as to

quantity in the inverse ratio of the age, and in which the fibres are

also more developed. On the pubis, the whole is almost homogeneous in

the fœtus; the transverse fibres do not become very apparent till a

more advanced age. The articulations of the knee, the jaw, &c. have

in their fibro-cartilages, the same arrangement. Ebullition extracts

from them then a much greater quantity of gelatine; they have more the

smooth appearance of the cartilages.

The membranous fibro-cartilages are in general developed early, those

of the ear, the eyes and the nose especially. We see them very evident

in the fœtus. I have observed in two acephalous infants, that, like

all the other parts of the face, they were of a remarkable size, and

much greater than that of the ordinary state. Besides, the whole

fibro-cartilaginous system is, in the fœtus, extremely soft, supple and

unresisting.

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