The affection is to be recognized by its peculiar clinical features,

and, if necessary, by means of the microscope. This instrument should

{719} always be employed in cases of doubt. At times it bears

resemblance to eczema and seborrhoea, and to psoriasis. From eczema it

may be distinguished by its circular or annular form, its

sharply-defined margins, its tendency to clear up in the centre, its

slight desquamation, and its history and course; the itching is usually

less marked than in eczema. Seborrhoea, when occurring on the chest and

back, often consists of circular patches similar in general features to

ringworm, but the scales are greasy, and are seated upon non-inflamed

skin; the scaliness of ringworm is the result of inflammation, while

that of seborrhoea consists of dried sebaceous matter. Moreover, in the

latter affection the sebaceous follicular openings are perceptibly

enlarged, and are indicative of the nature of the disease. In psoriasis

at times the patches clear up in the centre, and in such instances a

mistake in diagnosis might occur. The scaliness of psoriasis, however,

is always a marked feature; it is usually insignificant in ringworm.

Moreover, the characters of the scales are different. Occasionally the

circinate tubercular syphiloderm has been confounded with ringworm, but

the nature of the patch in the former disease, consisting of an

irregular and incomplete ring of elevated tubercles or infiltrations,

with, at times, ulceration, is so entirely different from the latter

affection that an error should not occur. It can scarcely be confounded

with favus if the peculiar yellowish, cup-shaped crusts of that disease

are kept in mind; the clinical features of the two affections are also

in other respects dissimilar.

The treatment consists in the application of the milder parasiticides,

the disease rarely proving obstinate. In exceptional cases, where the

affection is persistent, it will sometimes be found that the general

nutrition is below the standard; and in such instances constitutional

remedies of a tonic nature, as cod-liver oil, iron, quinine, and

arsenic, are serviceable. In children the skin is delicate and strong

remedies are not well borne; nor are they, as a rule, necessary. The

parts should be first washed with soap and water, and then the remedial

applications made; the lotion or ointment should be applied two or

three times daily. If a lotion, it should be dabbed on thoroughly; if

an ointment, it should be thoroughly rubbed into the patches. The

sulphite or hyposulphite of sodium, in lotion or ointment form, a

drachm to the ounce; sulphurous acid, full strength or diluted;

ammoniated mercury, thirty to sixty grains to the ounce of lard or

vaseline; corrosive sublimate, two to four grains to an ounce of

alcohol or water; an ointment of sulphur, a drachm or two to the ounce;

tar ointment, a drachm or two to the ounce; carbolic acid, ten to

thirty grains to the ounce of water or lard,--are all parasiticides of

value which may be employed in this disease. In obstinate cases

chrysarobin, five to thirty grains to the ounce of lard, may be

cautiously used, or it may be applied in collodion or gutta-percha

solution, 5 to 10 per cent. strength. In tinea circinata cruris

applications such as the above, but stronger, are serviceable. R. W.

Taylor speaks well of a solution of corrosive sublimate in tincture of

benzoin, two to four grains to the ounce, painted over the parts. The

chrysarobin ointment or solution already mentioned may also be

especially referred to. Hebra's modification of Wilkinson's ointment

(see Scabies for formula) is useful in these cases. In tinea

trichophytina unguium the nail should be pared or scraped, and one of

the parasiticides applied.

* * * * *

{720} TINEA TONSURANS.--Tinea tonsurans, or ringworm of the scalp, is

characterized by circular or irregularly-shaped, variously-sized,

scaly, more or less bald patches, showing the hair to be diseased and

usually broken off close to the scalp. It is met with in children,

especially in those under the age of twelve years; it is rarely seen

after puberty. It begins as one or more small, round, erythematous,

scaly spots, which may be minutely papulo-vesicular or vesicular about

the periphery. Soon by peripheral growth typical circular patches of

various sizes are formed, averaging about an inch in diameter. More or

less itching is usually complained of. A typical patch is

circumscribed, slightly elevated, reddish, grayish or slate-colored,

with more or less scaling, usually thin or bran-like in character, with

the hairs broken off close to the scalp. The color varies with the

complexion of the individual; in marked blondes it has usually an

inflammatory tint, while in those of dark hair and skin it is

bluish-gray or the color of slate. The hairs on the affected areas are

involved early in the disease, becoming lustreless, dry, brittle,

twisted, breaking off close to the skin, with their free extremities

ragged and uneven, having a gnawed or nibbled look. They are easily

extracted, or often break off within the follicles, appearing then as

blackish dots. A variable degree of baldness occurs, which, however, is

rarely permanent. In some instances the patch is non-inflammatory and

free of scales, the loss of hair, which is more or less complete,

taking place rapidly, such cases bearing resemblance to alopecia

areata. As a rule, several patches varying in duration and size are

present. They may remain discrete, or coalesce and form irregular

areas. The vertex and parietal regions are favorite localities,

although any region of the scalp may be invaded. It is not uncommon to

see patches of the disease on the non-hairy portions of the body at the

same time.

In some cases, especially in those ill nourished and scrofulous, the

inflammation may be of a higher grade, resulting in the production of

discrete or grouped pustules, terminating in crusting; or the disease

may assume the condition known as tinea kerion. This latter is seen

most commonly in scrofulous subjects. Beginning ordinarily as a simple

patch of ringworm, the affected area soon becomes inflamed, swollen,

oedematous, elevated, red, shining and boggy, covered with a mucoid

secretion which is poured out from the openings of the hair-follicles.

The stubby hairs soon fall out, leaving the patch more or less bald.

The surface is uneven and studded with the foramina, or small cavities,

containing the mucoid or sero-purulent secretion, corresponding to the

dilated hair-follicles. It bears resemblance to abscess and carbuncle.

An analogous condition is not uncommon in tinea sycosis. It may occur

with the usual form of tinea tonsurans or alone. Occasionally the

disease cures itself in this way. It may, however, be chronic. Its

causes are not understood: it may be due to the presence of the fungus

in the deeper portions of the hair-follicles, or at times to

over-treatment. It is a rare manifestation.

Other unusual forms of the disease are occasionally noted. The spots

may in the early stages be merely scaly, with or without inflammatory

symptoms, and the hairs long and firmly seated, resembling eczema or

seborrhoea. Later, however, the hairs break and the characteristic

stumps are the result. As ringworm becomes chronic (its usual course)

the clinical features become different. The disease exists in irregular

areas--as {721} a rule, non-inflammatory and more or less scaly,

especially about the follicles. The hairs are short, stubby, and broken

off near the skin or in the apertures of the follicles; in the latter

case the skin has a punctate or dotted appearance. This condition is

noted especially in brunettes; in blondes the hairs are somewhat longer

and apt to drop out insidiously. Or, the disease may be disseminated,

involving here and there over the scalp small groups of follicles, the

hairs being short, the follicles slightly enlarged, with a tendency to

scaliness; in these cases the disease may be easily overlooked.

Ringworm of the scalp is a common affection, and is observed among the

rich as well as the poor, but is most frequent in those suffering from

malnutrition. It may be communicated by means of caps, combs, brushes,

and the like. It is frequently seen in schools and children's asylums,

sometimes affecting a large proportion of the inmates. The fungus

(trichophyton) invades the epidermis, hair-follicle, bulb, and shaft.

The follicle becomes distended and raised; the hairs are permeated with

the fungus (spores markedly predominating), are disintegrated, and

destroyed. The perifollicular tissue may, in severe cases, be invaded.

The spores are present in great abundance, the mycelium existing

scantily.

As a rule, there is no difficulty in recognizing the disease. The

presence of stumps of hair having a gnawed or nibbled look, the

prominent follicles, more or less baldness, and slight or decided

scaliness, together with the history and course, constitute a clinical

picture that is scarcely mistakable. If necessary, microscopical

examination of the hair will give positive information. For this

purpose one or two of the short, stubby hairs should be selected,

placed upon a slide, a drop of liquor potassæ added, allowed to stand a

few minutes, and then examined with a power of two to five hundred

diameters; the hairs will be found full of spores, the shafts being

completely disintegrated. If a few drops of chloroform are poured upon

a patch of ringworm of the scalp and allowed to evaporate, the hairs

and follicular openings affected become whitish or light-yellow, which,

according to Duckworth, is pathognomonic. It is to be differentiated

from squamous eczema, seborrhoea, psoriasis, and alopecia areata. The

history of eczema is different: it rarely begins as circular spots,

spreading peripherally; the margins are always more or less irregular;

the hairs are not involved, but remain seated firmly in the follicles;

the itching is marked, whereas in ringworm it is usually slight.

Seborrhoea is non-inflammatory; the scales are greasy; the hairs are

not broken off; and the margins of the patch are ill defined. In

psoriasis the scaling is a marked feature; the hairs are not involved;

and the disease is usually to be found typically expressed on other

parts of the body. From alopecia areata ringworm may be differentiated

by its clinical features; in the former disease the baldness is usually

complete, the skin devoid of scales, non-inflamed, smooth, shining, and

the follicles, as a rule, less prominent than normal; the absence of

the characteristic stumps of ringworm may also be noted. In obscure

cases the microscope is to be employed.

An opinion regarding the length of time required to cure ringworm of

the scalp should always be guarded; while some cases respond in several

weeks, in others several months or more may be required. Relapses are

liable to occur. External remedies are, as a rule, alone required. In

{722} chronic cases, however, where a condition of malnutrition exists,

proper food, fresh air, and suitable internal remedies, as cod-liver

oil, iron, and arsenic, are to be advised; cleanliness is of

importance. The patches should be washed frequently with warm water and

castile soap or sapo viridis, the frequency depending upon the scaling

and the amount of disease, and also somewhat upon the remedies

employed. Occasional washing of the entire scalp is also to be advised.

Remedial applications should be, as a rule, made twice daily. In acute

or recent cases, in which the fungus has not penetrated deeply into the

hair-follicles, it often yields to the ordinary parasiticides, without

the necessity of epilation. In cases commonly encountered, however, the

disease has already lasted some length of time, and epilation becomes

essential. The main difficulty in the treatment of tinea tonsurans is

to bring the remedy in contact with the fungus; otherwise the affection

would be as easily curable as that occurring on the general surface. To

a great extent epilation aids in overcoming this difficulty, as the

parasiticide is then able to permeate the emptied follicle; and in

addition to this advantage the extracted hairs take with them the

fungus contained within their structures. The hair within and around

the affected areas should be clipped short, or, if the patches are

numerous, the hair of the entire scalp should be cut, or, what is

preferable in many cases, shaved. If the scalp is shaved, a few days

elapse before epilation is possible. On a shaved head there is no

chance for any diseased area, however small, to escape observation; in

the treatment of the disease as met with in institutions this procedure

is almost essential. In epilation the loose hairs on the patches and

about the borders should first receive attention. For this purpose a

small, broad-bladed, short forceps may be employed, a few hairs at a

time being seized. A portion of the diseased area should be carefully

gone over each day until all are removed. After each epilation the

parasiticide is to be applied.

Corrosive sublimate, two to four grains to the ounce of alcohol or

water, is a reliable remedy; also oleate of mercury, in the form

preferably of a 25 per cent. ointment. An ointment such as the

following is serviceable in many cases:

Rx. Ugt. picis liquidæ,

Ugt. hydrarg. nitrat., aa. drachm ij;

Ugt. sulphuris, drachm iv.

M. Ft. ugt.

Or, in place of the tar ointment in the formula, carbolic acid in the

same or less quantity may be substituted. The officinal tar, sulphur,

and ammoniated mercury ointments may also be referred to as useful. In

small disseminated patches carbolic acid in glycerin, one to three

drachms of the former with enough of the latter to make an ounce, will

often prove serviceable. Thymol sometimes proves of value, and may be

prescribed as advised by Malcolm Morris:

Rx. Thymolis, drachm ss;

Chloroformis, drachm ij;

Olei olivæ, drachm vj. M.

Coster's paste is also serviceable:

Rx. Iodinii, drachm ij;

Olei picis, ounce j. M.

{723} This is painted on the patch, and permitted to remain on until

the crust comes off, then is reapplied: a few applications are

sometimes sufficient. In tinea kerion the hairs are extracted and a

mild parasiticide applied: sulphurous acid, a weak solution of

corrosive sublimate, carbolic acid, ten to twenty grains to the ounce

of water, or a weak ointment of the oleate of mercury or of white

precipitate, may be employed.

If the disease proves obstinate, resisting the above treatment, it may

be necessary to adopt stronger applications with a view of producing an

acute inflammation in the part. To be efficacious the inflammatory

action should be marked. For this purpose croton oil is used. It should

never be employed when the disease is extensive; or if used in such

cases a small area only, not exceeding that of a quarter dollar, should

be treated at one time. Although valuable, the remedy is severe, and

must be used cautiously. It may be applied pure or weakened with two or

three parts of olive oil. An application requires but a small quantity,

as it is apt to involve the skin beyond the area of application. In

some cases a single application is sufficient; in others several or

more are necessary before the requisite amount of follicular

inflammation and suppuration results. The applications should be made

by the physician, as it is not a safe remedy to entrust to attendants.

After the application the part should be poulticed, and subsequently

epilation practised and mild parasiticides employed. Instead of using

croton oil, the patches may be painted with glacial acetic acid or

cantharidal collodion once a week, and mild parasiticides, as

sulphurous acid, carbolic-acid lotion, or sulphur ointment, applied in

the interval. From time to time in the treatment of the disease,

usually at intervals of from three to four weeks, applications should

be discontinued a few days, and a microscopic examination of the scales

and hairs made: if fungus is found, treatment is to be resumed.

* * * * *

TINEA SYCOSIS.--Tinea sycosis, or parasitic sycosis, is a disease

confined to the hairy portions of the face and neck in the adult male,

involving the hair and hair-follicles, with inflammation of the skin

and subcutaneous connective tissue, and the formation of tubercles and

pustules. It is popularly known under the name of barber's itch. It

usually begins as one or more small, red, scaly spots, similar, in

fact, to ringworm on the non-hairy portions of the surface. The redness

and scaliness increase, and swelling and induration are noticed. In a

short time the hairs are involved, become dry, brittle, inclined to

break, and begin to fall out, the same changes occurring as noted in

ringworm of the scalp. The fungus passes to the hair-follicles;

perifollicular inflammation is set up, and results in the formation of

deep-seated tubercles, varying in size from a pea to that of a cherry,

giving the part a distinct nodular appearance. These coalesce and give

rise to lumpy patches. The surface is of a deep reddish or purplish

color; pustulation is noted about the openings of the hair-follicles.

More or less crusting may take place; if removed, the hairs may come

away with it. The amount of suppuration depends upon the grade of

inflammation. Sometimes the hair-follicles are destroyed and permanent

alopecia results.

The disease may involve a small area, appearing as a

sharply-circumscribed, prominently-raised, deep-seated, nodular,

coin-sized patch, with or without a purulent discharge from the emptied

hair-follicles or with {724} crusting; or the whole bearded region of

the neck and chin may be invaded. It is not common on the upper lip or

the upper bearded portion of the cheeks. Burning and itching are

usually present, but are variable as to degree. The disease tends to

chronicity. It is not uncommon at the same time to see patches of

ringworm on other portions of the body. It is markedly contagious,

although individuals differ as to susceptibility. It is often

contracted at the hands of a barber. The fungus (trichophyton) which

gives rise to the disease invades the same parts as when seated upon

the scalp--the epidermis and the hair and hair-follicles; the latter

are usually found permeated with spores, the mycelium being scanty.

The affection is not common, its frequency varying in different

countries. It is to be distinguished from simple (non-parasitic)

sycosis, pustular eczema, and the vegetating syphiloderm. In simple

sycosis the process is comparatively superficial and confined to the

hair-follicles; the hairs are not involved, and in the beginning, at

least, are seated firmly in the follicles. In tinea sycosis the skin

and subcutaneous connective tissue are extensively involved, resulting

in the formation of nodular masses--a condition that is characteristic;

the hairs are affected, are loose, and often fall out. In doubtful

cases the microscope will determine. From pustular eczema it may be

differentiated by its history and course: its clinical features are

entirely dissimilar. Eczema is never attended with the nodular and

tubercular formation peculiar to this disease, nor are the hairs

affected. The absence of ulceration will distinguish the disease from

the vegetating syphiloderm. Tinea sycosis when occurring as a

circumscribed patch may sometimes resemble carbuncle.

In the treatment epilation with the use of parasiticides is employed;

as a rule, the disease yields readily to treatment. Crusts, if present,

are to be removed by means of oily applications and washings with

castile soap (or if necessary sapo viridis) and warm water. The parts

should be clipped or shaved, preferably the latter. Although this

operation is painful at first, later it may be accomplished without

much discomfort; shaving every second or third day is frequent enough.

In the interval epilation is to be practised. The milder parasiticides,

as sulphite or hyposulphite of sodium, a drachm to the ounce of water

or ointment; sulphurous acid, full strength or diluted; citrine

ointment, two or three drachms to the ounce of vaseline or lard; and a

weak sulphur ointment,--are all useful. A 10 to 30 per cent. ointment

of oleate of mercury is a valuable remedy; the same may be said of a

solution of corrosive sublimate, two to four grains to the ounce of

water or alcohol. In addition, the other parasiticides mentioned in the

treatment of ringworm of the body or scalp may be referred to. The

applications should be made twice daily; together with epilation they

should be continued until microscopical examinations of the hairs give

negative results.

Tinea Versicolor.

Tinea versicolor is a vegetable parasitic disease due to the

microsporon furfur, characterized by variously-sized,

irregularly-shaped, dry, slightly furfuraceous, yellowish, macular

patches, occurring for the most part upon {725} the trunk and in

adults. The affection may be slight, consisting of several small

patches on the upper part of the chest, or so extensive as to involve

the greater part of the trunk, neck, axillæ, flexures of the elbows,

groins, and in very rare instances the face. It never occurs on the

scalp, hands, or feet. As commonly met with, it is a disease of the

trunk, especially the anterior portion of the thorax. It begins as

small yellowish or brownish, fawn-colored, furfuraceous spots scattered

over the region affected. These gradually increase in size, new spots

may appear, and considerable surface may be invaded. In size they vary

from a pea to large irregular patches, and are scarcely, if at all,

elevated. The larger patches are irregular, and usually formed by

coalescence of several smaller spots. Rarely patches may clear up in

the centre and assume an annular form.

The number of patches varies; as a rule, a half dozen or more are

present; in other cases they may be numerous. They show more or less

furfuraceous scaling, varying with the amount of perspiration and the

frequency with which the parts are washed. The scaling, even when it is

insignificant or when the patches are apparently smooth, may be easily

detected by scratching or scraping the surface. Slight itching is

ordinarily present, especially when the parts are unusually warm; it is

rarely marked. The color is usually a pale or brownish yellow. In

sensitive skins at times the affection causes more or less hyperæmia,

and the spots have a reddish hue. The course of the disease is

variable, sometimes spreading rapidly, while in most cases its progress

is slow. It is, as a rule, persistent, existing years. Relapses are not

uncommon.

The cause of the disease is the vegetable fungus, the microsporon

furfur. It invades the superficial portion of the epidermis. The

affection is but slightly contagious. Those between the ages of twenty

and forty, of either sex indifferently, are most frequently the

subjects of the disease; it rarely if ever occurs in children or in

elderly people. It is commonly observed in those whose nutrition is

below the standard, especially in persons having pulmonary phthisis. It

is a common affection, and occurs, in varying proportions, in all parts

of the world. Scrapings or scales moistened with liquor potassæ may be

examined with a power of three to five hundred diameters, and the

peculiar features of the fungus well brought out, as the fungus exists

in abundance. It consists of mycelium and spores, the former appearing

as short, slender, variously-sized, straight or curved, twisted, wavy,

or angular threads, crossing one another in all directions. In

appearance they are homogeneous or granular, and often contain spores,

especially about the joints. The spores are ovalish or round, sharply

contoured, small in size, with a nucleus and slightly granular plasma.

They show a marked tendency to aggregate and form groups--an

arrangement which is characteristic of this fungus. The growth is found

in every stage of development from mycelium to spores.

There should be no difficulty in recognizing the disease if its

characters and distribution are kept in mind. In doubtful cases the

microscope will prevent error. It is at times confounded with chloasma,

vitiligo, and the macular syphilide. In chloasma, in which there is

merely an increase of pigment in the rete, there is no scaling, the

outlines are ill defined, and it is usually seen about the face--a

region that is practically exempt in tinea versicolor. Moreover, the

coloration in the parasitic disease is due to the {726} fungus, which

has its seat in the superficial epidermis and can be readily scraped

off. With ordinary care it is impossible to mistake vitiligo for the

disease in question. The macular syphiloderm is to be distinguished by

attention to the distribution, character, and size of the lesions.

Tinea versicolor is practically a disease of the trunk; the macular

syphiloderm is usually distributed over the whole surface; and if it is

the latter disease concomitant symptoms of syphilis are almost

invariably present.

A system of practical medicine. By American authors. Vol. 4 · 第 95 / 116 段