2. Can abortion be prevented? The presence of an ovum being determined,

our attention must next be directed to the possibility of its

preservation. The distension of the os, especially the amount of

hemorrhage, must guide the practitioner in seeking an answer to this

important inquiry, upon which treatment must depend. The amount of

hemorrhage is indicative of the separation of the ovum, but a slight

flow continued for days is by no means as dangerous to gestation as a

profuse instantaneous discharge. The os may be dilated, but if the

hemorrhage is slight and the ovum out of reach, the progress of

abortion may yet be prevented even after pains have been inaugurated,

the first pains being those of dilatation. The appearance of rhythmical

pains, indicative of expulsive contractions, leaves little hopes for

the practitioner to check the course inaugurated. Even if the ovum can

be felt, abortion may still be prevented, but if it protrude through

the gaping os, little is to be expected, though even under these

circumstances prevention is still said to be possible if the hemorrhage

has not been severe. But if the liquor amnii has passed, there is no

possibility of saving the ovum at any time, though it is claimed that

even this can be done if pain or hemorrhage alone exists and the latter

be not too severe. Even if the separation has not progressed so far

that abortion is inevitable, the question must arise whether it be

judicious to attempt prevention or whether abortion should be

furthered. This depends upon the condition of the embryo, whether it is

destroyed or not; if no previous abortions have occurred, and no {507}

known cause, especially predisposing or local, exist, if the size of

the uterus corresponds to the period of pregnancy, and there are no

symptoms of mechanical interference or trauma, an effort should be made

to preserve the ovum; but if there be cause sufficient to account for

its death, if the uterus be more hard and round, wanting in the elastic

oval of normal gestation, if it be smaller than usual at the period of

gestation at which the interruption has occurred, death of the embryo

and ovum may be supposed, and, notwithstanding the possibility of

prevention, abortion should be hastened and completed, the ovum and

membranes expelled.

3. Is abortion completed? Difficult as it often is to answer the

question whether the ovum has been expelled, it is almost impossible to

say whether the abortion has been fully completed, whether the last

remnants of tissue have been evacuated. If the physician has been

present or the clots have been saved from the time of the inaugural

hemorrhage, it may be easy to determine the condition of affairs; but,

unfortunately, these are usually thrown away, and the attendant comes

at a late period, at one of suffering and exhaustion, when masses of

blood, quantities of clots, with whatever of the ovum they may contain,

have been removed. If present, he should crumble each clot and float

the coagula in water. Fibrin and blood will soon wash away, and the

shreds of tissue become separated and remain floating in the fluid.

An examination of all pieces that have passed will readily reveal the

existing stage; but ordinarily the physician has no such clue. The

hemorrhage has ceased, the uterus is firmly contracted, the os is

closed, and the diagnosis is exceedingly difficult, but it must be

determined. If left to nature, time will disclose the true condition of

affairs: if the ovum has been expelled, the uterus will rapidly

diminish in size, the appearance of the discharge will change--it will

become more thin and pale; but if the uterus remains firmly contracted,

and does not diminish in size, it is probable that the membranes are

retained, and the renewal of exertion, of work, or of a succeeding

menstrual period--if not the first, the second--will bring about a

recurrence of the hemorrhage and the completion of abortion. If the

uterus remains large, hard, globular, it is probable that the ovum, or

at least the greater part of the membranes, remains in the cavity.

Unless the hemorrhage has ceased and the os be closed for some time

previous to the coming of the physician, he will find the uterus low in

the pelvis, the os still yielding, except when ergot has been given or

ice applied, and by the introduction of the finger into the uterus the

condition of the cavity will be determined: this will in all cases be

readily accomplished by pressing with one hand firmly upon the fundus

and examining with one or two fingers of the other; if not easily done

in this way, the entire hand should be introduced into the vagina; the

uterine cavity may then be thoroughly swept with the examining finger;

but, though this will reveal an enclosed ovum, the membranes can by no

means be detected with ease, and will often escape observation; hence

the dull curette is in place: it will sever such tissues as may still

be adherent. All excellent instrument, especially if the os be small,

is the Récamier curette, or the modification which I have devised for

the purpose. Should any doubt exist, dilatation should be at once

resorted to for {508} curative as well as diagnostic purposes; a rapid

dilatation is in place--not instrumental, but by the tupelo or

sea-tangle: this affords positive knowledge of the state of the case,

and the cavity can then be thoroughly cleansed. Even the sponge tent is

harmless if the abortion is completed, as the cervix is still dilatable

and yielding, easily expanded. At all events, the diagnosis is

unquestioned and the treatment clear. This is by far better than the

expectant plan, which is most commonly followed for fear of

interference, allowing the patient to continue perhaps for a month or

more in ignorance of her condition--allowing her to resume her labors,

exposed to sepsis, hemorrhage, and, in the most favorable case,

expulsion of the ovum at any time.

If the os is dilated, the finger should be introduced--if necessary the

hand--into the vagina, which can easily be done if the fundus be

approximated by the other hand; better still, to use the curette, and I

would advise the large blade of my instrument; the small one can at all

times be passed into the cavity of the uterus during or immediately

after abortion, and usually the larger one also. This examination, if

with the scoop, consequent upon dilatation, should be followed by an

antiseptic injection, but I would unquestionably advocate a correct

diagnosis, whatever means may be necessary to obtain it, as appearances

are so deceptive. We need but recall those by no means rare cases which

to all appearances are those of completed abortion, yet the patient

does not perfectly regain health and strength, and if an examination is

made the os is found patulous and membranes or parts of the ovum are

retained. If examination and dilatation be neglected, a coming

menstrual period will discharge the disintegrating mass, or local and

constitutional disturbances, even septicæmia, may be looked for.

PROGNOSIS.--As to prognosis, it is the mother whom we must consider,

the dangers present and future, the attachment and dimensions of the

ovum, and the possibility of continued gestation. The prognosis of

traumatic or criminal abortion is worse than that of the spontaneous

form, the result of natural causes, because it is inaugurated by shock,

by injury, and inflammatory conditions which are aggravated by the

congestion and contraction accompanying the expulsion, for which the

tissues are entirely unprepared; whilst in natural, spontaneous

abortion, usually the result of some morbid condition, some disease of

the system, a cachexia, uterine disturbance, or death of the embryo and

ovum has preceded, and a retrograde metamorphosis to a certain extent

has been inaugurated; some preparation at least has been made for the

coming expulsion; hence the separation is more natural, less violent,

less liable to be followed by evil results.

The prognosis is invariably favorable if proper medical aid is summoned

in the early stages, but actually it varies greatly, as does the course

of abortion--whether completed in a reasonable time or of longer

duration, more favorable in the former, less propitious in the latter;

if hemorrhage has been profuse or comparatively slight, but of long

duration, anæmia is liable to result: if expulsion is long protracted,

the dangers of subinvolution, metritis, and perimetritis are great: if

the expulsive pains cease before the complete expulsion of ovum or

membranes, retention, putrefaction, and sepsis may be inaugurated, and

subinvolution, endocervicitis, and endometritis will follow.

{509} The embryo is scarce to be considered: it may be saved if the

hemorrhage has not been too severe and accompanied by pain, if the ovum

does not protrude into the cervix. The inflammation which usually

accompanies traumatic or criminal abortion greatly aggravates the

prognosis, but, however good it may be in individual cases, the result

will depend greatly upon the after-treatment, upon the time allowed for

proper involution, and upon the assistance given it. Though the

prognosis at the time of abortion may be a most favorable one for the

mother, the result is seriously affected by the care taken during the

period of involution, the after-treatment, which is by far more

important than generally supposed.

TREATMENT.--The successful treatment of abortion requires knowledge,

judgment, and resolution on the part of the practitioner, and in

importance it is equivalent at least to the management of labor at

term. Two lives may even be at stake, though the opportunity of saving

the embryo is, as a rule, afforded only during the period of

prophylactic and preventive treatment, as vitality is ordinarily

destroyed in the embryo when abortion, as the result of natural causes,

is once inaugurated: the life of the mother is not in question, as it

is in labor at term, but her health is even more endangered. Attention

is now forcibly called to the subject by earnest discussions between

the adherents of the expectant and those of the progressive method of

treatment, but mainly to the treatment of actual abortion; prevention

and after-treatment have been neglected. Important as is the method of

treatment employed in case of retention of membranes or ovum, the

necessity for such interference, especially the frequency of abortion,

would be greatly diminished if the family physician were thoroughly

imbued with the importance of the subject and could impress the same

upon his patients. If the dangers arising from such premature

interruption of gestation were appreciated by the laity and medical

attention summoned in the early stages, the management of abortion

would become more simple and more successful, and the cases of

retention which cause such suffering and injury to women would be far

less frequent.

Before entering upon the treatment proper it may be well to review

briefly the necessary adjuncts, as proper preparation will aid

materially the course to be adopted.

Preparations Necessary with Regard to the Patient.--Many of the

preparations necessary in the lying-in chamber are desirable in cases

of abortion as well. Attention should be paid to the bowels, as a

costive condition will interfere to some extent with the manipulations

as well as a rapid and favorable course of expulsion and involution; at

best, it is liable to make the patient uncomfortable. The bladder

should be evacuated, especially before active measures are resorted to,

and the patient should be so clad in night-gown and sacque, with long

hose and drawers, that she may be moved and manipulated without

exposure.

The bed should be prepared with rubber cloth and quilts, and sufficient

quilts, cloths, and towels should be on hand; a bed-pan is desirable,

and also a fountain or bulb syringe; the bed should be so placed that

the physician may be at the right hand of the patient, and convenient

to the light when she is placed in Sims's position of the dorsal

decubitus for operative interference.

{510} Antisepsis.--Cleanliness and antisepsis should be observed in the

management of abortion as strictly as in that of labor or in surgical

operations, as sepsis, either in the form of acute infection or an

insidious undermining of the constitution, is among the more frequent

of the dangerous consequences which follow in the wake of abortion.

Circumstances permitting, it is desirable that carbolated vaseline or

vaseline with iodoform, carbolated or some similarly prepared soap, be

on hand, and also permanganate of potassium, carbolic or boracic acid,

and iodoform. I am in the habit of prescribing carbolic acid for the

convenience of use: carbolic acid 2 ounces, alcohol 1 ounce, with 7 of

glycerin, which is as concentrated as may be well used (1 to 5, or 20

per cent.), and a proportion readily diluted to 2½ or 5 per cent.

Before and after examinations the hand should be washed in carbolated

water or some such disinfectant--permanganate of potassium, corrosive

sublimate, or boracic acid--as it appears desirable to use. If carbolic

acid is used, the parts should be cleansed with a 2 or 3 per cent.

solution. After interference or repeated examinations the vaginal

douche should be used, certainly after completion before leaving the

patient. If instrumental interference be necessary, and the ovum or

membranes forcibly removed, the cavity of the uterus should be washed

with hot water, from 115° to 125° F., containing 5 per cent. of

carbolic acid, the hot water serving styptic purposes. This may

suffice, but it is frequently desirable to mop the cavity with the

above-named solution or even the pure liquid after more active

interference, especially if some disintegration has taken place and is

indicated by odor.

After the use of tampons the vagina should be washed with a 2 or 3 per

cent. solution, or 1:2000, of corrosive sublimate; and it is even well

that the cotton, before being introduced, should be anointed with

either carbolized vaseline or carbolized oil (carbolic acid 2 drachms,

olive oil 3 ounces). Iodoform serves an excellent purpose for

disinfection of tampons, especially such as are packed into or against

the cervix, and as an application to the cavity after the removal of

the putrid contents following the hot douche. Borated cotton, or even

ordinary cotton or prepared tow, should be on hand to use during the

after-treatment in place of cloths for the purpose of receiving the

discharge: it is warm, soft, forms a good filter, and can be thrown

away or burnt when soiled, whilst the cloths ordinarily used, and often

very offensive, are kept for the wash.

Medication.--The most important of all the remedies is opium; in

preventive treatment it may be called a specific. It is far preferable

to the hypodermic injection of morphine, serving to relax and quiet the

uterine muscle and to lessen hemorrhage; for the latter purpose it is

often combined with acetate of lead--from ¼ to 1 grain of opium mixed

with ½ to 1 grain of acetate of lead, to be given at a dose and

repeated when necessary. Ipecacuanha combined with opium acts well in

relaxing the tension.

Viburnum prunifolium has long been used as a uterine sedative in these

cases in those States where the plant is endogenous, and its use has

been widely disseminated since it has found so able an advocate in

Jenks. The preparations are not all equally effective, but in the early

stages the fluid extract given in teaspoonful doses, according to the

amount of hemorrhage and pain either hourly or every two or three

hours, has a most {511} decided effect in allaying threatened abortion,

in checking hemorrhage, and in quieting pains. It seems to be a uterine

sedative. Several ounces may be taken, and successful cases are

reported where the pending expulsion was averted and gestation

continued to a successful termination after four ounces had been used.

Digitalis combined with acetate of lead also deserves recommendation as

an effective remedy in the early stages. Quinine may be given to

stimulate the system and further uterine contraction, and is invaluable

in an asthenic condition or if disintegrating shreds be present.

Nervines, valerian, asafoetida, valerianate of ammonia, bromide of

potassium, are of great service throughout the entire course of

abortion, as the patient is usually in a nervous almost febrile state.

Alone they may serve to allay the irritating symptoms in the early

stages, and answer well in preventing the disagreeable effects of

opium. Asafoetida may be given by injection or in pills, from ½ to 2

grains at a dose.

Clysmata tend to irritate, and should not be used as long as we may

hope to prevent threatened abortion. Such remedies as are indicated in

the treatment of this condition, especially opium and nervines, must

nevertheless at times be given by injection, as the stomach may refuse

to receive and retain them in the irritated condition which accompanies

this state. The clysms should always be warmed, of body temperature:

two tablespoonfuls of milk of asafoetida or gum arabic form an

excellent vehicle, though water or milk thickened with flour or starch,

which is always on hand, will do quite well.

Should it be necessary to move the bowels, castor oil is one of the

best remedies, whilst cathartics, especially aloes and similar drugs,

must be avoided as long as there is hope of preserving the ovum: they

certainly further expulsion. Ergot should not be used until after the

uterine cavity is emptied, and is decidedly contraindicated whilst the

ovum or any of its parts remain adherent in utero. The dangers arising

from the use of ergot in the early stages, whilst the ovum is still

intact, are rupture of the membranes and forcible contraction, which

always prolongs expulsion of the ovum or its membranes; the circular

fibres, which predominate, are stimulated most forcibly to action, more

particularly so under the conditions which usually exist in abortion:

the muscle of the uterine body is hindered in its contraction by the

adhesions of ovum and decidua, especially if these membranes are

infiltrated; and, moreover, in cases of abortion the tissues of the

womb itself are often more or less diseased; the lower portion of the

uterus and cervix alone is free to act, the circular fibres of the

internal os contract most readily under the influence of ergot, whilst

the activity of the fundus is interfered with; thus closing of the

outlet and incarceration of the membranes are liable to result. This

popular and dangerous drug must not be given until the tissues are

expelled, or, if desirable by reason of excessive hemorrhage, its use

may be resorted to under one condition: if the membranes are detached,

not only free in the uterine cavity, but entering that of the cervix;

they may be found massed together firmly, by compression of the uterine

walls, into a conical or pyriform mass; and when this has to a great

extent passed the internal os ergot may be given. This drug, so

dangerous in obstetric practice, is still used with altogether too much

freedom in this country, and it would be far better to do without it

than to {512} continue the prevalent abuse. I have insisted that this

drug must not be given in labors or abortion until the contents of the

uterine cavity have been removed. Although but one of our prominent

obstetricians approved of the position I took in 1883, and I was then

freely attacked, I now urge the point more earnestly, and the doctrine

is more commonly accepted: in Germany such men as Martin, Spiegelberg,

and others have succeeded in doing away with this dangerous remedy

altogether in the institutions under their care, restricting its use to

the non-gravid uterus.

As a styptic, hot water, carbolized, serves the best purpose: in the

early stages as vaginal douche, in the later as an intra-uterine

injection at 120°, it is an invaluable remedy, preferable to other

styptics, as it cleanses and removes the coagula. When the cavity has

been emptied, especially after the forcible removal of the membranes,

it is well to apply carbolic acid to the surface; and it is better for

this purpose than tincture of iodine or perchloride of iron, either of

which is only to be used in case that hemorrhage does not yield to the

before-mentioned remedies.

Anæsthetics.--Though bromide of potash, morphine, or opium may suffice

for the relief of the pain in ordinary cases, the use of an anæsthetic

is not only desirable, but necessary, if more active measures are

resorted to. For purposes of rapid dilatation and the removal of an

adherent ovum or membranes anæsthesia is almost indispensable; without

this the suffering of the already nervous, debilitated patient is

excessive; the uterine and abdominal muscles are tense, and operations

thus greatly impeded. An anæsthetic should be given in a rapid

dilatation on account of the pain, as well as the greater facility of

operating; and it is most necessary in an attempt at expression, as, if

made without an anæsthetic, the abdominal muscles are so tense that the

uterus cannot be well manipulated from without. I myself prefer

chloroform.

Instruments.--A speculum, a dull curette, a sharp scoop, a vulsellum

forceps, and uterine dressing-forceps are essentially necessary. Any

speculum may be used. The best is Sims's if the semi-prone position be

used, or Simon's in the dorsal decubitus. The Schroeder's or my forceps

is necessary to steady and bring down the uterus for the introduction

of tent or finger and the use of the scoop or the application of

styptics. This is in the main the American bullet-forceps, an

instrument far superior to the sharp vulsellum which is so popular. The

curette I would most recommend is my own modification of Récamier's

instrument of pliable metal, one blade resembling that of Récamier's,

but curved somewhat more like the uterine sound--sharp upon one side,

dull upon the other--to be used for the purpose of severing the ovum or

membranes in the line of their adhesion: this is so narrow that it can

be introduced into the os even after contraction if this be not almost

tetanic, as after the giving of ergot. The other blade is larger, broad

and flat, more spoon-like, to be used in case of moderate dilatation of

the os, both, however, being for the purpose of severing the adhesions

and leaving the ovum intact. The broad blade serves as a lever to

remove the ovum or membranes when detached. But if the membranes be

ruptured, it is of service in separating these from the uterine wall,

leaving them as complete as possible, which will always facilitate

removal or expulsion. The irritation caused by the severing of the

adhesions with this instrument frequently suffices to inaugurate

uterine contraction; and ovum or {513} membranes, being once liberated,

are then compressed by the uterine muscle into one mass, thus affording

a resistance which the uterus is enabled to grasp and expel. This

method I believe to be far more rational than the removal of the

membranes with the sharp instrument: it furthers the process of nature

more strictly, separating rather than cutting away the tissues, as does

the latter. The sharp scoop is an instrument which is only to be used

for firm adhesions in secondary cases, where the progress of abortion

has temporarily ceased and the membranes have become more firmly

attached, especially where disintegration of such adherent parts has

taken place to some extent; it is necessary and cannot be dispensed

with where remnants have been retained for months and have become

firmly attached, simulating polypoid growths. I object to the use of

the sharp scoop in recent cases, because it is preferable to follow the

line of demarcation indicated by nature, and separate the membranes or

the ovum, if still entire, in this strait; whilst the sharp scoop

removes them piecemeal, cutting deep into the mucosa at one place, and

possibly leaving pieces of embryonic tissue in another.

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