SYMPTOMATOLOGY, COURSE, AND DURATION.--At first there is heat, dryness,

and more or less pain in the affected parts, followed by a profuse flow

of yellow pus. There is also tumefaction, hypersensitiveness, and often

pruritus. Follicular vulvitis is the term employed to indicate an

inflammation of the mucous or sebaceous glands and of the

hair-follicles of the vulva. This disease may be the result of any of

the causes of purulent vulvitis, as alluded to in the preceding clause.

The subjective symptoms are common also to the purulent form.

Objectively, the mucous membrane will appear to be very red in spots,

resembling in this respect the raised papillæ of the tongue. These

spots frequently bleed on slight provocation. The internal surface of

the nymphæ and vestibule is the seat of the disease when the mucous

glands are involved, but where the sebaceous glands are mainly affected

the inflamed papillæ will be found on the surface of the labia and at

their juncture anteriorly. In the course of the inflammation a drop of

pus will exude from the papules, and they then gradually {390}

disappear. Occasionally, collections of exudate from the diseased

glands accumulate beneath the labia minora, concealing the diseased

surfaces and becoming quickly very offensive. The disorder, though

sometimes persistent, is seldom chronic. The acute affection may be the

cause of urethritis in the male closely resembling gonorrhoea if

coition occurs during its existence, and thus not infrequently giving

rise to suspicion of infidelity.

TREATMENT.--In the matter of treatment, touching the inflamed points

with carbolic acid or caustic sometimes favorably influences the course

of the disease. Cleanliness is the most important item in the treatment

of the two forms of the disease, for without it the application of

remedies will be of little avail. Strict attention to this, with

perfect rest of the parts, will not infrequently be all that is

requisite to effect a cure, but in cases that do not yield to this

treatment sedative, astringent, or alterative applications are

indicated. These should be applied after bathing. In the purulent

variety such remedies as the lead-and-opium wash after the following

formula will prove serviceable:

Rx. Tinct. opii, fluidounce j;

Plumbi acetat. drachm j;

Aquam ad fluidounce viij.

Lint may be saturated with this lotion and applied between the labia.

If the disease does not yield to the treatment already mentioned in the

course of two or three days, a solution of argentic nitrate (gr. x to

ounce j) should be brushed upon the parts, and between the intervals of

its application bismuth or starch may be kept constantly on the parts.

In cases associated with vaginitis a much stronger solution is

sometimes required. (Vide chapter on Vaginitis.) The author has used

powdered iodoform in some cases with very good results.

[Illustration: FIG 28. Follicular Vulvitis (Huginer).]

In the follicular variety the disease is more severe and usually of

longer duration than the purulent, although the principles of treatment

are essentially the same. In this as in the other variety cleanliness

is of paramount importance, frequent washing being very essential. To

the inflamed follicles such applications as nitrate of silver,

persulphate of iron, and carbolic acid are the more frequent remedies

used in this disease. After the application of any of these remedies

the parts should be rendered dry, and then a piece of soft linen or a

roll of absorbent cotton should be smeared with vaseline or soaked with

carbolized glycerin and inserted within the vulva in a way to keep the

labia apart. Occasionally the practitioner will meet with a chronic

form of vulvitis, and the rareness of its occurrence is fortunate, for

the reason {391} that it is a very obstinate and intractable variety of

the disease. Vulvitis is very frequently associated with vaginitis,

owing to the fact that the mucous membrane is continuous in both vulva

and vagina. On this account the principle of treatment of inflammation

of either locality is essentially the same. To avoid repetition, the

reader is therefore referred to the section on Vaginitis for a more

detailed description of treatment.

There is a form of this disease described by Vinay[17] as ulcerous or

aphthous vulvitis. This is an affection peculiar to childhood,

occurring only when the general health is much impaired. It is often a

sequel of fevers, and may even become epidemic. It attacks children of

any age, but is of more common occurrence in infancy. The disease

appears first upon the mucous membrane in the form of small and round

patches of a white or grayish-white color, which soon ulcerate, and at

a more advanced stage are liable to become gangrenous. This variety of

vulvitis has long been known, and is mentioned in the works of

Hippocrates. This disease is rarely met with in this country.

[Footnote 17: _Nouveau Dict. de Méd._, tome xxxiii., 1885.]

Phlegmonous Inflammation of the Labia Majora.

DEFINITION.--The adipose and areolar tissue which compose the greater

bulk of the labia majora often become the seat of acute inflammation,

in consequence of direct injury, excessive or awkward coition, exposure

to cold, from irritating discharges, scratching in pruritus, vulvitis,

or that peculiar blood-state which predisposes to the formation of

boils or carbuncles.

SYMPTOMATOLOGY AND DIAGNOSIS.--The patient will first complain of heat

and pain, increased by standing or walking, and later throbbing and

shooting pains in the affected parts. In the outset the part is

congested, followed by induration from effusion in the loose tissues,

and next suppuration ensues. An examination in the last-named stage

will reveal the existence of an abscess in one labium. The diagnosis is

by no means difficult, but the physician, however, should bear in mind

that this same locality may be the site for pudendal hernia, a

dislocated ovary, hæmatocele, or vulvitis.

TREATMENT.--In the outset the inflammation may be caused to disappear

by resolution, by means of cold and sedative lotions, such as the

lead-and-opium wash, saline laxatives, non-stimulating diet, and

perfect rest. In the majority of cases the disease proceeds to

suppuration. When it is found that resolution is unattainable, then

means should be taken to promote and hasten suppuration. This is best

effected by the frequent application of hot poultices. The mistake is

often committed of permitting too long intervals to elapse between the

application of poultices, and allowing the one applied to become cold

before another one takes its place. The patient can be saved many hours

of suffering by keeping hot applications constantly on the inflamed

labium. As soon as suppuration is detected the abscess should be

opened, for two reasons aside from the one of affording relief: First,

the tissue resists early natural evacuation; second, owing to the

laxity of the tissues, pus will sometimes force itself upward toward

and through the abdominal ring.

{392} Furuncles of the Labia.

DEFINITION.--Closely resembling phlegmonous inflammation are the

furuncles or boils which are quite common on the labia. They occasion

much pain and distress, for the reason that they are very obstinate and

apt to recur, one forming as soon as its predecessor has apparently

healed. In many instances these boils seem to be consequent upon

inflammation of sebaceous glands. They differ in size, some being no

larger than a pea, while others are the size of a filbert.

TREATMENT.--This should be constitutional and local. Quinine, arsenic,

cod-liver oil, and other remedies of a tonic character should be

administered. The bromide of arsenic has been used by the author in a

few cases with quite satisfactory results. As soon as one of these

furuncles shows that it contains pus, it should be freely opened and a

crucial incision made to prevent immediate healing; after which

poultices should be applied. These small boils are extremely painful,

and are very troublesome, owing, as previously stated, to their

liability of recurrence. To prevent their recurrence is one of the

reasons why immediate healing of the incisions should be prevented. If

contraction of the sacs of the abscesses does not occur, pus will

continue to be formed and the tissues in their immediate neighborhood

will become indurated. In this way the furuncles may become of a

chronic character. To further facilitate healing and aiding their

contraction the sacs should have applied to them some stimulating

remedy, such as carbolic acid or nitrate of silver. Edis says that

painting the surface of the affected labium with tincture of iodine is

beneficial in some instances.

One of the most important requisites in treatment is perfect

cleanliness.

Pruritus Vulvæ.

DEFINITION.--Pruritus vulvæ, although merely a symptom of disease,

characterized by itching of the vulva and contiguous neighborhood at

times wellnigh intolerable, has, because of its occasional obscure

etiology and severity, always been considered by medical authors as a

disease of itself, instead of a symptom of other disorders, in

treatises on diseases of women.

ETIOLOGY.--Predisposing and Exciting Causes.--It frequently occurs from

external irritation, as animal parasites, or such as may be produced by

acrid discharges, particularly in gonorrhoea and uterine cancer,

changes in the normal composition of the urine, especially diabetic,

and not infrequently during the menstrual flow. Pruritus may occur in

connection with inflammation of the uterus and vagina without any

irritating discharge; likewise it occurs in diseases of the urethra,

bladder, and kidneys. Sometimes masturbation may be the cause as well

as the effect of pruritus. Secondarily, there may be an insufferable

itching in consequence of the continued titillation or irritation of

the parts, although masturbation by no means invariably leads to

pruritus. The habitual use of opium or alcoholic drinks often causes

intractable forms of this disorder. Edis states "that the custom of

immoderate tea-drinking is a by no means infrequent cause of pruritus."

But instances of pruritus occur where all {393} of the causes mentioned

are lacking, and they are instead purely of a reflex character, such as

are met with in women about the time of the change of life and during

the latter months of pregnancy, or from the presence of worms in the

rectum. If the worms migrate to the vulva, as they sometimes do, the

irritation then becomes direct. Interference with the circulation of

the vulva by pregnancy and tumors may cause pruritus: unquestionably,

certain varieties of the disorder are idiopathic or neurotic.

SYMPTOMATOLOGY AND COURSE.--When the complaint has existed for some

time, the itching will be pretty well diffused from the pubis backward,

but in more recent cases it may be localized at the perineum, nymphæ,

clitoris, or portions of labia. The itching is not always constant, but

subject to exacerbations. It is usually much worse when the patient

becomes heated from exercise or is warm in bed, thus preventing comfort

or sleep, and thereby adding an additional complication to treatment.

The sufferer naturally seeks relief by scratching the involved tissues,

and for this very transient satisfaction spreads the disease by

increasing the irritability of the parts and inducing a condition

closely resembling eczema.

TREATMENT.--Inasmuch as the etiology of the complaint is often

uncertain, as heretofore stated, it is highly important that the

physician should ascertain if possible the cause of the disease, and

thereby be better enabled to treat the complaint intelligently. In case

the itching can be traced to the animal parasites most common in this

region, such remedies as the black or yellow wash, mercurial ointment,

or the oleate of mercury will usually prove sufficient; but if it be

found that the Acarus scabei is the cause of the itching, the

application of the ordinary sulphur ointment will destroy this parasite

and the itching will consequently cease. If due to uterine catarrh or

any vaginal affection, attention should be directed to the removal of

the primary disorder by appropriate means, for it cannot be expected

that itching of the vulva can be relieved so long as there is any

irritating discharge constantly exciting it. The most important measure

of all is perfect cleanliness. This can be secured by sitz-baths,

sometimes several being necessary daily. At the same time, the vagina

should be syringed with warm water or water with the addition to it of

such remedies as are used for the relief of leucorrhoea. The irritated

surfaces of the vulva should be prevented from coming in contact by

vaseline spread upon absorbent cotton or lint, or by powders, such as

bismuth, starch, etc.

In case there is an unmistakable acrid discharge from the uterus

causing pruritus, proper topical applications should be made to as much

of the endometrium as is diseased; the vagina should be thoroughly

douched night and morning, and then there should be placed against or

around the neck of the womb one or more tampons of cotton saturated

with the boro-glyceride or with glycerin, in which has been dissolved

borax or acetate of lead in the proportion of ounce ss of one of these

salts to ounce ij of glycerin.

In some instances, where there is a profuse discharge, simply packing

the vagina with dry salicylated or borated cotton will suffice. This

should never be allowed to remain longer than twelve hours without

removal. In those cases where the discharge is less acrid a single

tampon saturated with one of the remedies named or glycerin alone, and

placed {394} against the cervix daily, will suffice, as it will prevent

the discharge from coming in contact with the vulva. In severer forms

of this affection a number of tampons saturated in the same manner will

be more efficacious, and still permit the patient to move about. When

several tampons are used they should be loosely rolled, and each one

should have a string attached for convenient removal. In the mean time,

topical applications can be made to the vulva, and washing of the parts

will not interfere with the tampons. The author has found the following

prescription of Thomas very efficacious as a vaginal injection and wash

for the vulva:

Rx. Plumbi acetatis, drachm ij;

Acidi carbolici, scruple ij;

Tr. opii, fluidounce j;

Aquæ, pint iv. M.

Another prescription which has demonstrated its value is:

Rx. Bismuthi subnitratis,

Acaciæ pulv. aa drachm ij. M.

Sig. Add water to the consistency of cream and apply frequently with a

brush.

A somewhat similar prescription, to be applied in the same way, is the

following:

Rx. Pulv. acaciæ, drachm ij;

Bals. Peru, drachm j;

Ol. amygdalæ, drachm iss;

Aquæ rosæ, fluidounce j; M.;

or,

Rx. Acidi carbolici, drachm ij;

Glycerinæ, fluidounce j;

Aq. rosæ, q. s. fluidounce viij. M. Ft. lotio.

In all cases of pruritus, except from parasites, much benefit can be

derived from washing the parts two or three times daily in a weak

solution of bicarbonate of sodium (half a tablespoonful in a quart of

water, with a tablespoonful of eau de Cologne).

In pruritus from diabetes some relief may be afforded by the

administration of alkaline mineral waters or salicylate of sodium. In

pruritus associated with chronic cystitis the last-named remedy is very

useful.

In pruritus of a neurotic character a solution of the muriate of

cocoaine of the strength of 4 per cent., sprayed upon the parts or

applied with a camel's-hair brush, has often in the author's hands

afforded relief when every other application has failed.

One of the latest publications relating to the treatment of pruritus

vulvæ is a paper by Kustner,[18] agreeing with Schroeder that the

results of operative treatment for pruritus vulvæ are encouraging. This

author publishes several cases resulting successfully. A synopsis of

one will suffice to show his mode of treatment. A patient, unmarried,

suffered for a long time from uterine catarrh and pruritus vulvæ: the

former was relieved after prolonged treatment, but there still remained

two symmetrical spots between the hymen and labia minora which were the

seats of most troublesome itching and were exceedingly sensitive to

touch. These portions of the mucous membrane were rich in sebaceous

glands, and were also studded with small retention-cysts. The author

dissected off {395} the two elliptical portions of mucous membrane,

each 1 cm. broad and 3 or 4 cm. long, and containing the small

retention-cysts, and then united each wound with interrupted sutures.

The pruritus entirely disappeared, and did not again return, though

some years after the patient again suffered with uterine catarrh. Other

cases are related by the same author, notably one case of pruritus

where there was a lacerated perineum. The operation for repair of this

perineum was performed, with the result of the permanent disappearance

of the pruritus. The author does not give any definite rule as to how

and in what cases he should have recourse to operative treatment, but,

admitting that pruritus may arise from causes heretofore mentioned in

this article, he asks whether those cases where secondary pathological

changes have occurred in the vulvar mucous membrane cannot be

definitely cured by excision of the affected portion. Not enough cases

of cure of pruritus by surgical treatment have been reported to fully

establish the theory of Kustner, yet it is a matter of sufficient

importance to merit our attention and warrant further investigation.

[Footnote 18: _Centralbl. f. Gyn._, No. 12, 1885.]

Hyperæsthesia of the Vulva.

DEFINITION.--This is a disorder first described by Thomas under the

above caption.[19] It consists of a hypersensitiveness of the nerves

supplying some portion of the mucous membrane of the vulva. Sometimes

the area of tenderness will be confined to one of the lesser lips or it

will be limited to the vestibule, and in other cases a number of parts

may be simultaneously affected. "It is a condition of the vulva closely

resembling that hyperæsthetic state of the remains of the hymen which

constitutes one form of vaginismus," and doubtless is often confounded

with the latter.

[Footnote 19: _Op. cit._, p. 145.]

ETIOLOGY.--It is more common about the time of change of life, and

occurs more frequently among women of hysterical diathesis where there

exists a morbid mental condition with a tendency to melancholia. In

some instances the disease seems to be excited by vulvitis or vascular

growths in the urethra.

SYMPTOMATOLOGY.--The slightest friction causes intense pain and

nervousness, and even a current of cold air produces very great

discomfort. Coition causes such severe pain that for this cause the

subject usually consults her physician. As in vaginismus, the mental

distress is often of an exaggerated character, in some instances

bordering upon monomania.

PATHOLOGY.--In this disorder there are no indications of inflammation

except occasional spots of erythematous redness. It is not a neuralgia

in a true sense of the term, but an abnormal sensitiveness of diseased

nerves supplying the vulva.

DIAGNOSIS.--The affections most liable to be confounded with this are

vascular growths (or irritable caruncles) of the urethra and

vaginismus, but ocular inspection and digital examination will enable

the physician to determine the character of the disease.

TREATMENT.--This is far from satisfactory in many cases. Thomas speaks

most discouragingly concerning it, and states that "the treatment of

this condition is most unsatisfactory."

{396} The author has at this time a patient with hyperæsthesia of the

vulva who has been treated by him for many months, and up to the time

of this writing has obtained no relief. Thomas recommends sending the

patient "away from home, where, in addition to enjoying changes of air,

scene, and surroundings, she would live absque marito."

In this, as in all disorders which depend on or are associated with the

hysterical diathesis, galvanism and massage are, as a rule, of decided

benefit. In addition, general tonics, such as arsenic, strychnia,

quinia, and iron, should be prescribed. If any local affection exist,

such as vulvitis or urethral vegetations, it should be cured first.

Warm fomentations, the frequent use of warm water, sedative lotions,

and ointments consisting of opium or its salts, carbolic acid,

chloroform, and iodoform, are useful topical remedies. Much benefit may

be derived by the application of a 4 per cent. solution of

hydrochlorate of cocoaine by means of a spray or soft brush. Strong

solutions of alum and tannin have sometimes proved beneficial.

No good results have been derived from the use of the knife or caustics

in cases where they have been used.

Tumors of the Vulva.

Under this head will be included any enlargement, neoplasm, or

adventitious growth which has the vulva for its site. The most common

are the following, which will be considered in the order named: viz.

Cysts, Hydrocele, Hernia, Hypertrophy, Elephantiasis, Hæmatoma, Cancer,

and Urethral Caruncle. There are other growths of the vulva, such as

fibroma, lipoma, sarcoma, lupus, etc., but they are of such rare

occurrence that their discussion is necessarily omitted.

Cysts and Inflammation of the Vulvo-Vaginal Glands.

The frequent concomitance of cysts and abscesses in these glands has

caused the author to consider them here under the same caption.

The most frequent cysts of the vulva are those springing either from

the ducts or glands of Bartholini, or, as more commonly known, the

vulvo-vaginal glands, situated near the lower part of the labia. Cysts

having their origin in the ducts are single and are invariably of an

oval form; such also is the more common shape of those springing from

the gland, yet sometimes they are lobulated, of an irregular form, and

comprise one or more in number. Inasmuch as this same locality is

sometimes the site of hernia, and cysts of the labia often of a similar

form, the physician should be positive that the tumor is a cyst before

having recourse to any active mode of treatment.

If fluid accumulates in a cyst in such quantity as to cause the subject

inconvenience or discomfort, surgical treatment will be required, of

which there are three different modes in common use.

The first mode is to remove by scissors a segment of the sac, allowing

escape of its contents, after which the cavity is filled with marine

lint or carbolized cotton, which is allowed to remain for about

forty-eight hours {397} before renewal. By this plan of treatment the

sac will usually be obliterated. Another method is to freely open the

cyst and apply some caustic, preferably the galvano- or thermo-cautery.

In the absence of either of the last named nitric acid may be used with

good effect. The third and last method has in the author's experience

proven the most efficacious, though objection has been made to it on

account of its being a more bloody operation--namely, complete

extirpation of the gland.

The causes of inflammation of these glands are the same as those that

cause vulvitis; in truth, they are often accompanying disorders. The

symptoms are pain, heat, itching, and an increased redness,

particularly about the opening of the duct. If a finger be pressed over

the location of the gland, it will elicit signs of pain.

[Illustration: FIG. 29. Abscess of Glands of Bartholini.]

In the outset of the inflammation it is felt hard and unyielding, but

two or three days later a fluctuating tumor may be easily discerned. An

abscess of the gland should be easily distinguished and rarely mistaken

for a cyst. There are the history and ordinary signs of inflammation to

aid in diagnosis. If, on the contrary, there is simply a cyst, it can

be rolled about under the finger and no indications of pain produced.

Further, it may exist an indefinite length of time, and unless the

gland from some cause become inflamed no great inconvenience is

experienced. It is not an infrequent occurrence, from some cause, for

inflammation to attack a cyst-wall, in which event the symptoms of

inflammation ensue. Where such is the case the treatment should be the

same as in inflammation of the gland--namely, absolute rest and any

soothing or anodyne lotions which favor restoration. Should indications

of suppuration occur, it should be promoted by the frequent application

of hot poultices. If the pain is not severe, the abscess may be left to

nature; but if it be severe, then the abscess should be emptied by a

free incision at the most prominent point.

Hydrocele, or Cysts of the Canal of Nuck.

A system of practical medicine. By American authors. Vol. 4 · 第 50 / 116 段