TREATMENT.--Under all circumstances where the bladder cannot empty

itself, the catheter should be used, and the bladder should be washed

out, kept clean, and disinfected. All the suggestions laid down for

catheterization and vesical injection in the section on Chronic

Cystitis are applicable here and need not be repeated. It is

particularly necessary to disinfect the catheter on each occasion

before it is introduced. This is best effected by washing the catheter

outside and inside with a 5 per cent. solution of carbolic acid in

water, and finally washing it outside with clean water, before its

introduction. If the bladder is over-distended, it should not, as a

rule, be entirely emptied at the first introduction of the catheter,

for fear of possible collapse, or, what is more to be dreaded, setting

up acute cystitis by suddenly taking off all the internal pressure from

the vessels in the walls of the weakened bladder, to which pressure the

circulation has become accustomed. If, therefore, the bladder is

emptied inadvertently, it is better to inject a few ounces of warm

water containing borax in solution (a teaspoonful to the pint), and

leave it in until the next catheterization. The quantity left in may be

reduced at each sitting. By careful attention to these means most cases

of over-distension due to atony or paralysis may be relieved without

the intervention of cystitis, or with so little that it does not become

a serious factor in the case.

The medical treatment of these cases is less important than the

mechanical. Under the latter alone and improvement in general health

curable cases often get well. Milk diet is of service, and iron and

tonics of considerable value in proper cases. Electricity has not

yielded satisfactory results in my hands, and I have not derived the

advantage from ergot which is often claimed for it. In cases of atony I

think I have seen good results sometimes follow the use of strychnine

internally in pretty full doses. The same remedy under the skin acts

more promptly and more effectively if it is to do any good at all. In

true paralysis of central origin the cure of the bladder depends upon

relief of the original disease and local treatment to the bladder.

Hysterical women sometimes feign paralysis in order apparently to

secure the sympathy and personal attention of the physician. The

application of the actual cautery above the pubes, and entrusting a

female nurse with the function of catheterization, is generally

effective treatment in these cases.

Hemorrhage from the Bladder.

After all sorts of wounds and injuries to the bladder, and in cases of

rupture of the viscus, blood is found in the urine. In certain medical

{135} conditions, in scurvy, hemorrhagic eruptive diseases, cases of

vicarious menstruation, it has been noticed. In strangury due to

cantharides, or in any condition of acute or chronic cystitis with

considerable spasm of the bladder, the urine contains more or less

blood. Especially is this true if ulceration exist at or near the neck

of the bladder, as in tubercular or cancerous cystitis.

In cases of stone in the bladder one of the cardinal symptoms is

vesical hæmaturia, while in villous growth often the only symptom of

the malady is repeated attacks of more or less profuse bleeding from

the bladder coming on unexpectedly, without obvious exciting cause, and

showing no regularity in the length of the intervals between the

hemorrhages or the intensity or duration of the latter. Outbursts of

unexpected hemorrhage are not uncommon in connection with some cases of

enlarged prostate and chronic cystitis, while these outbursts are the

rule, sooner or later, in most cases of true cancer of the bladder.

The DIAGNOSIS is often very important--that is, in a given case to

decide whether the blood comes from the bladder or from the kidney.

This may usually be ascertained by a very simple manoeuvre, especially

when the flow of blood is not excessive: a silver catheter of short

curve is introduced and the urine drawn off, the bladder gently washed

several times without moving the catheter, and the shade of red in the

wash noted. Now, the bladder being slightly distended with warm water,

the point of the catheter is moved somewhat roughly in all directions

and made to touch different portions of the wall of the bladder. The

water is now allowed to escape, and its deepened color will decide that

the hemorrhage has a vesical origin, for manipulations of a silver

catheter in a healthy bladder will not occasion a flow of blood. In

doubtful cases on two occasions I succeeded in locating the point

whence the blood escaped as follows: In one I passed a soft catheter,

and washed the bladder until the wash escaped nearly clean; I then

withdrew the catheter until the point reached the membranous urethra

(the bladder having been left full of clean water), and immediately

passed the instrument again and withdrew the contents of the bladder,

which were now brilliantly colored, thus locating the bleeding point in

the prostatic sinus. In the other case, that of a young man with

moderate stricture, whose urine was nearly solid with blood, I noticed

that no blood escaped by the meatus between the acts of urination;

therefore the bleeding point was posterior to the membranous urethra.

Was it in the prostate, the bladder, or the kidney? To decide this I

passed a soft catheter and washed the bladder until the wash flowed

clear. I then injected some warm water, withdrew the catheter, and

caused the patient to empty the bladder. The flow was brilliant with

blood. In both these cases I effected a cure by one application of

solid nitrate of silver through the urethra to the prostatic sinus.

The TREATMENT of vesical hæmaturia is the treatment of the cause,

which, if possible, must be ascertained. For the symptom itself the

internal use of iron, turpentine, opium, gallic and tannic acids, are

of service. I have not derived any advantage from ergot. Locally, rest

in bed, ice over the region of the bladder, and avoidance of straining

at urination are generally all that is necessary. I have had good

results from injecting the bladder with a solution of alum, gr. i-ij to

ounce j of warm {136} water, and cures have been effected by injecting

nitrate of silver in solution. It is not well to inject iron in

solution, since this substance makes a hard clot, and a soft clot is

preferable. When the bladder fills up with a solid clot of blood, the

best treatment, according to my experience, is to administer opium

freely and diluent drinks. The urine slowly dissolves the clot, which

has already arrested the hemorrhage, in most cases by its pressure, and

the blood flows away as a dark coffee-ground material, sometimes nearly

black. If the catheter is used, the clot broken up or dissolved with

pepsin or other substance, and washed or pumped out, a new clot is apt

to form at once; and although this treatment is based on high

authority, and is often practised successfully, it is a question

whether the patient would not in many cases do as well, or better, by

being let alone, soothed by opium, until the urine dissolves the clot

and nature relieves him.

New Growths in the Bladder.

These belong strictly to the province of surgery, but they fall also

under the notice of the physician. Tubercular disease may involve the

whole mucous surface or only the neck of the bladder; cancer may

infiltrate its walls or grow out as a solid tumor in the vesical

cavity; fibrous, sarcomatous, and myomatous new formations, polypi, and

cysts, simple and hydatid, have been encountered; villous growths, both

benign and cancerous, may occur. These morbid deposits give rise either

to recurrent hemorrhage or to varying grades of chronic cystitis. The

diagnosis is often difficult, the treatment generally palliative. Much

has been done of late in an operative way for the relief of tumors of

the bladder, and some brilliant results have been secured by operations

through the perineum as well as above the pubes. A tumor of moderate

size may be detected by the searcher within the bladder, and often may

be grasped in a lithotrite and measured. Such a tumor can generally be

plainly felt by conjoined palpation in a thin subject, one hand pressed

firmly down behind the pubes and two fingers of the other hand passed

into the rectum. Recently, Sir Henry Thompson has advocated vesical

exploration for purposes of diagnosis through a median incision in the

perineum, as for median lithotomy, and has practised it a number of

times with a large measure of success. I have made the same exploration

several times, and have encountered and successfully removed one tumor.

The expedient is worth bearing in mind for use in any obscure cases. It

is probably less objectionable and more likely to yield valuable

information than the exploration by introducing the whole hand into the

rectum (Simon's method).

{137}

SEMINAL INCONTINENCE.

BY SAMUEL W. GROSS, A.M., M.D.

DEFINITION.--By the term seminal incontinence, which is synonymous with

involuntary or abnormal seminal emissions, pollutions, and

spermatorrhoea, is meant the involuntary discharge of semen beyond the

limits of health. Although usually described as a distinct disease, it

is symptomatic of, and, as a rule, primarily dependent upon, weakness

or exhaustion, along with exaggerated irritability, excitability,

impressibility, or mobility of the centres which preside over erection

and ejaculation. Hence it should be regarded as a motor neurosis, and

not as a functional disorder of the testes.

CLASSIFICATION.--Involuntary seminal losses embrace three conditions,

which constitute as many varieties of the affection, and which may

exist separately, or pass into one another, or be combined. These

varieties are, first, nocturnal losses or pollutions, which occur

during sleep, and are generally attended with an erection, erotic

dream, and pleasurable sensation; secondly, diurnal pollutions, which

take place when the patient is awake, are excited by trivial mechanical

or psychical causes, and are associated with imperfect erection and

diminished sensation; and, thirdly, spermorrhagia, or spermatorrhoea,

in the strict acceptation of that term, which is characterized by a

constant escape of a slight amount of seminal fluid, without the

orgasm, pleasurable sensation, or impure thoughts, or during

micturition and defecation.

1. Nocturnal Pollutions.--By far the most common of the varieties of

seminal incontinence is the first, or that in which the emissions occur

during sleep under the influence of an erotic dream, and which may,

therefore, be regarded as an exaggeration of the normal or

physiological condition. In health, provided the subject leads a

continent life, the number of emissions varies greatly, and as they are

merely reflex signs of distension of the seminal passages, they are not

pathological nor are they attended with ill effects. The knowledge of

this fact is of great practical importance, as it frequently enables

the physician to assure his patient that the emissions are not

abnormal, thereby relieving his mind of a great weight. It is, of

course, to be remembered that the frequency of nocturnal pollutions

depends upon age, climate, habits, temperament, constitution, diet, and

predisposition, and that young men who suffered during childhood from

nocturnal incontinence of urine are particularly obnoxious to them.

Their frequency also varies greatly in the same person, and it is

scarcely possible to determine what constitutes the standard {138} of

health merely by the intervals of their repetition, since a number

which would be normal in one person would be abnormal in another. In

men, however, who possess sound nervous systems and who do not trouble

themselves with sexual matters an emission every fortnight is a sign of

excellent health; and even if they should occur at intervals of several

days, they are not inconsistent with temporary good health. The latter

statement is well exemplified by a case which came under my observation

in 1882. A druggist, twenty-seven years of age, had had for six years

from three to live emissions a week, and occasionally two during a

single night, attended with erections and voluptuous dreams, without

the slightest evidence of impairment of his health. In all such cases,

however, as well as in those in which the emissions have occurred at

longer intervals for a number of years, it only requires a little

longer time for general symptoms to manifest themselves.

Nocturnal pollutions are to be regarded as pathological when they occur

in married or single men who indulge in regular intercourse; when they

are followed by backache, headache, enfeeblement of the functional

powers of the brain, mental depression, and bodily or mental lassitude;

when they take place without erections or dreams; when they accompany

or follow acute or chronic diseases; when they coexist with diurnal

pollutions or spermorrhagia; and, finally, when they are complicated by

one of the varieties of impotence, which may be the only indication

that the emissions are abnormal or one of the effects of impairment of

the functions of the genital nervous centres. The associated symptoms

of myelasthenia and cerebrasthenia vary very much in degree in men of

apparently the same amount of vigor and tolerance, and in whom the

pollutions occur with equal frequency, or they may even be absent

altogether.

2. Diurnal Pollutions.--Ejaculation of semen during the day is

fortunately of comparatively infrequent occurrence, since it indicates

a more serious condition than do losses of seminal fluid occurring when

the patient is asleep, the genital organs and the centres which preside

over them being highly impressible or in a state of irritable weakness.

In what may be regarded as the lesser form of the affection the

ejaculation is due to slight peripheral irritation, induced, for

example, by friction of the clothing, crossing of the legs repeated

several times, horseback exercise, driving over rough streets, riding

in railway-cars, or even shaving, combing the hair, or shampooing the

head; while in the more aggravated variety an emission is induced by

psychical irritation, such as reading libidinous books, the sight of

indecent pictures, dwelling upon sexual ideas, or the mere sight of a

female. In the former of these varieties there is a fair erection, but

the sensibility is blunted; in the latter the erection is flabby or the

penis is flaccid and there is little if any pleasure.

3. Spermorrhagia.--In the third phase of the affection, which is still

more uncommon than the second variety, there is a continuous passive

loss of semen, without erection or sensation--a condition which depends

upon paralysis and dilatation of the orifices of the ejaculatory ducts,

and which is most conspicuous during the acts of micturition and

defecation. The existence of spermatorrhoea, in the restricted sense of

the term, is denied by some authors, but I have myself met with it in

five instances, and typical cases have been recorded by other modern

writers.

CLINICAL HISTORY.--Seminal incontinence usually supervenes upon {139}

the interruption of sexual intercourse, especially when the subject has

been accustomed to excessive venereal indulgence, or, as more

frequently happens, upon the abandonment of the habit of masturbation.

Any one of these varieties may exist separately, but they gradually

pass into each other, and are variously intermixed in the advanced

grade of the affection. In the mild type there is increased frequency

in the occurrence of nocturnal pollutions, ejaculation taking place at

intervals of several days or for two or three nights in succession,

when there is a respite for a week or ten days. The emissions are

associated with disturbances of the nervous system, referable to the

brain or spinal cord or to the cerebro-spinal axis, of which mental

lassitude and muscular debility are the most common signs. When, as the

result of the increase in the irritability of the ejaculatory centre

and of the progressive weakness or exhaustion of the entire nervous

system, the case goes on from bad to worse, it usually pursues the

following course: Abnormal frequency of the nocturnal pollutions is

associated with pain in the back, headache, muscular fatigue, and

incapacity for sustained mental effort. With the increase in the number

of the emissions erection becomes imperfect, ejaculation on coition is

frequently precipitate, and the patient complains of dulness of

perception, impairment of memory, mental dejection, a dull pain in the

occipital region, weakness of vision, vertigo, palpitation of the

heart, trembling and numbness of the limbs, shortness of the breath,

flatulence, constipation, and other signs of gastric derangement.

Diurnal pollutions are now superadded, and intercourse is

impracticable, either from failure of erection or from premature

ejaculation. The general symptoms, too, are more serious. The patient

constantly broods over his condition, assumes that he has permanently

lost his virility, and the mental anxiety and dejection verge upon or

merge into a condition of sexual hypochondrism. The gait is unsteady;

the hands and feet are habitually cold; he is subject to wandering

neuralgic and rheumatoid pains; passes restless nights; loses flesh and

color; shuns society; imagines that every one recognizes his condition,

and fears to look one in the face; and is utterly incapacitated for

mental or physical exertion. With the still further increase of the

irritable weakness of the genitalia and nervous centres the semen flows

continuously out of the urethra, and its discharge is augmented during

defecation and micturition. Finally, the man becomes a confirmed

hypochondriac, and should he have inherited a tendency to insanity,

epilepsy, ataxia, or other nervous disorders, he may lapse into one of

these conditions.

In the early stage of seminal incontinence, when the nocturnal

pollutions overstep the natural limits, the ejaculated fluid is

unchanged. When, however, the pollutions are more frequent and diurnal

discharges coexist, the semen is watery and scanty; the spermatozoids

are smaller, comparatively few in number, and their movements are

liable to be abolished in less than an hour, while spermatic crystals

form more rapidly and more abundantly than in health. In the worst

cases, or those characterized by diurnal and nocturnal pollutions and

by the presence of semen in the urine, the spermatozoids are either

entirely absent, or, if they are present, they are motionless, stunted,

or variously deformed. In these advanced cases the ejaculated fluid,

which consists principally of the secretions of the seminal vesicles

and the prostate, frequently undergoes fatty {140} degeneration, as

indicated by granular epithelium, by molecular detritus, and even by

oil-globules in the protoplasm of the altered zoosperms. The entire

absence of spermatozoids, constituting the condition known as

azoospermatorrhoea, is of infrequent occurrence.

An examination of the genital organs discloses elongation of the

prepuce in nearly one-fourth of all cases; a rigid and pointed penis in

one-tenth; relaxation of the scrotum in about one-eighth; irritable

testes in 1 example out of every 25; varicocele in 1 case out of every

50; coldness of the genitalia in 1 case out of every 17; a feeling of

heat in 1 case out of every 33; and irritability of the bladder in 1

case out of every 25. It will, moreover, be found that seminal

incontinence is complicated by feebleness of erection, with precipitate

ejaculation on coition, in 22 per cent. of all cases; by the occurrence

of ejaculation on attempting intercourse, before penetration,

simultaneously with erection, or even before erection, in 16 per cent.;

and with total impotence in 5 per cent. of all cases. Prostatorrhoea is

also a not infrequent complication, while urethral strictures and

hyperæsthesia are nearly always present.

ETIOLOGY AND PATHOGENY.--Seminal incontinence is not a separate entity,

but one of many symptoms of general or local disorders, or of both

combined. In the majority of instances it must be looked upon as a

neurosis, diurnal and nocturnal pollutions representing a motor

neurosis with spasm of the seminal vesicles, and spermorrhagia

indicating a motor neurosis with dilatation and paresis of the orifices

of the ejaculatory ducts. In all of the varieties there is increased

susceptibility of the cerebral and spinal genital centres to factors

which in healthy persons are not productive of ill effects.

Like other nervous disorders, involuntary seminal emissions sometimes

manifest themselves in several members of the same family through

several generations, being the result of inherited predisposition. In

this class of cases the subjects are of a nervous, excitable, or

irritable temperament, somewhat anæmic, and possibly suffered during

infancy from nocturnal enuresis. Among the predisposing causes the most

common is indulgence in erotic fancies, which terminates in increased

reflex impressibility of the centres which preside over the genital

organs.

The affection is, however, usually acquired, being met with

particularly in single subjects toward the termination of the second

decade and between the second and third decades. Of these cases, at

least nine-tenths can be traced to masturbation, while the remainder

will be found to have had gonorrhoea or to have masturbated, suffered

from gonorrhoea, or indulged their sexual propensities in various ways.

Seminal incontinence is not common as the result of sexual coition, and

it is highly probable that when married men are affected the sexual

excess is engrafted upon a previously vicious habit. From a practical

point of view, it is of the first importance to be aware of the fact

that one or more strictures of the urethra will be found in 80 per

cent. of all cases, and that decided hyperæsthesia of the prostatic

portion of the urethra is present in 94 per cent. of all instances.

The rational explanation of morbid seminal emissions seems to be as

follows: Under the influence of erotic ideas, masturbation, sexual

excesses, or unsatisfied sexual excitement produced by dallying with

women, exaggerated irritability of the genital organs is induced, and

is {141} followed by subacute or chronic inflammation and abnormal

sensibility of the urethra, particularly of its prostatic division,

which terminate, in cases characterized by diurnal pollutions and

spermorrhagia, in relaxation and dilatation of the orifices of the

ejaculatory ducts. As the natural result of the constant excitability

of the terminal filaments of the nerves distributed to the prostatic

urethra, these nerves are alive to the slightest impressions, act as

peripheral sources of irritation, and induce permanent increased

mobility or irritability of the cerebral and spinal genital centres,

through which the motor nerves of the ejaculatory apparatus are thrown

into action, and an emission ensues.

Seminal incontinence is an occasional accompaniment of injuries of the

spine, and it is also met with during the progress of or convalescence

from acute and chronic diseases which are marked by disturbances or

exhaustion of the central nervous system. Thus, it may be symptomatic

of phthisis, variola, typhus, progressive muscular atrophy, and

incipient bulbar paralysis, ataxia, and paraplegia; while the habitual

use of opium and chronic alcoholism predispose to its occurrence.

Of the local causes referable to the genitalia, by far the most

important and most frequent are hyperæsthesia and inflammation of the

prostatic portion of the urethra, which are generally induced by

masturbation. These lesions constitute the primary source of the

trouble in the large majority of cases, and tend not only to excite

reflex pollutions, but to maintain the disorder by keeping the mind

occupied with sexual matters. Other common local causes are found in

congenital narrowing of the meatus, organic stricture of the urethra, a

redundant prepuce, balanitis, and the accumulation of smegma. Among the

more infrequent etiological factors may be mentioned herpes of the

prepuce, congenital shortness of the frenum, spasmodic stricture,

polypus of the deep urethra, spermato-cystitis, and epididymitis.

A system of practical medicine. By American authors. Vol. 4 · 第 16 / 116 段