JOHN SHAW BILLINGS, M.D.

[Dr. Billings is a surgeon and administrator of the first

rank. He is now a director of the New York Public Library.

Among his many published works are "Principles of Ventilation

and Heating," issued by the _Engineering Record_, New York.

The essay which follows appeared in the _Evening Post_, New

York. January 12, 1901, copyrighted. It is reprinted in a

volume entitled "The Nineteenth Century: a Review of Progress

During the Past One Hundred Years," published by G. P.

Putnam's Sons, New York, 1901, copyrighted. It is presented

here by the kind permission of Dr. Billings, the publisher of

the _Evening Post_, and G. P. Putnam's Sons.]

The word "medicine," as used in the title of this paper, includes all

branches of the art of prevention and treatment of disease and injuries;

all discoveries of methods of diminishing physical pain and of

prolonging life, and also that part of modern science which is concerned

with accurate knowledge of the structure and functions, normal and

abnormal, of the human body, and of the causes of diseases. In other

words, it includes not only therapeutics, medical and surgical, but also

physiology, pathology, and hygiene.

In all these branches of medicine greater progress has been made during

the last century than had been made during the previous two thousand

years. This progress has been largely due to improvements in methods of

investigation and diagnosis, resulting from increase of knowledge in

chemistry and physics; to better microscopes and new instruments of

precision; to experimental work in laboratories and to the application

of scientific method and system in the observation and recording of

cases of disease and of the results of different modes of treatment. The

introduction of statistical methods in the study of cases of disease and

of causes of death; the discovery of general anæsthetics; the adoption

of antiseptic [excluding microbes] and aseptic [uninfective] methods in

surgery, and the development of modern bacteriology--each marks a point

in the history of medicine in the nineteenth century.

The scientific demonstration that some diseases are due to the growth

and development of certain specific micro-organisms in the human body

dates from about twenty years ago, although the theory of such causal

relation is much older. Since 1880 it has been proved that anthrax,

Asiatic cholera, cerebro-spinal meningitis, diphtheria, one form of

dysentery, erysipelas, glanders, gonorrhoea, influenza, certain

epidemics of meat-poisoning, pyæmia and suppuration in general,

pneumonia, tetanus, relapsing fever, tuberculosis, bubonic plague, and

typhoid fever are due to minute vegetable organisms known as bacteria;

that malarial fevers, Texas cattle fever, and certain forms of

dysentery are due to forms of microscopic animal organisms known as

microzoa; and for most of these diseases the mode of development and

means of introduction of the micro-organism into the body are fairly

well understood. To the information thus obtained we owe the triumphs of

antiseptic and aseptic surgery, a great increase of precision in

diagnosis, the use of specific antitoxins [antidotes to organic

infection] as remedies and as preventives, and some of the best

practical work in public hygiene.

The evidence as to the increased powers of medicine to give relief from

suffering and to prolong life is most clear and direct in the records of

modern surgery--particularly in some of its special branches. In a large

proportion of certain cases in which the surgeon now operates with a

fair chance of success, such as calculus in the kidney or gall-bladder,

shot-wounds of the abdomen, and tumours of various kinds, there was no

hope in the year 1800, and the unhappy sufferer could only expect a

certain, though often a lingering and painful, death. In cases of cancer

of the face, tongue, breast, or uterus, the persistent pain, extreme

disfigurement, and offensive odors which attended them made death a boon

to be prayed for, if not deliberately sought, while now such cases, if

brought in time to the surgeon, can often be entirely relieved. The

knowledge of this fact has become general with the public, and patients

no longer defer an operation as long as possible, as was their custom

in days of old. Instead of having to look forward to the torture of

incisions, manipulations, and stitching, with but small hope of

surviving the exhausting suppuration and blood-poisoning which were such

common results, the patient now knows that he will inhale a little sweet

vapour, and sleep unconscious of the strokes of the surgeon's knife or

the pricks of his needle. He may dream wondrous dreams, but he will soon

awake to find himself in his bed staring at the trained nurse standing

by his side, and wondering vaguely why the operation has not begun. He

does not have to look forward to weeks and even months of daily

dressings. The surgeon will glance at his temperature record and at the

outside of his bandages, but will probably not touch them for a week;

and when he does remove them nothing will be seen but a narrow red line

without a trace of suppuration. These improved methods not only preserve

the mother for her children, and the bread-winner for the family, but

they greatly contribute to the public good by shortening the period of

enforced idleness and unproductivity after operations.

Some of the greatest triumphs of modern surgery are obtained in cases of

disease or injury of the abdominal organs. The removal of ovarian and

uterine tumours is now so common and successful that it is not easy to

realize that a hundred years ago there was practically no help or hope

for such cases. In former days, the lists of deaths contained many

cases reported as inflammation or obstruction of the bowels, or as

peritonitis. It is now well understood that most of these cases are due

to disease of a little worm-like appendix connected with the large

intestine on the right side of the lower part of the abdomen,

inflammation of which, known as appendicitis, causes excruciating pain,

and often produces internal abscesses and death. An operation for the

removal of such a diseased appendix is now common, and in most cases

successful. The operation for the removal of calculus, or stone, from

the urinary bladder dates from over twenty-five hundred years ago, and

no one knows who first performed it. Within the last century it has been

largely superseded by an operation which crushes the stone to powder

within the bladder, and removes this powder without the use of the

knife. The removal of calculi from the kidney or from the gall bladder,

and the removal of a diseased kidney, are new operations, made possible

by improved means of diagnosis, anæsthesia, and antisepsis [determining

disease, causing insensibility, and excluding microbes]. Wounds of the

intestines were formerly thought to be almost necessarily fatal, and

nothing was done for them except to stupify the patient with opium. Now

in such cases the abdomen is opened, the lacerations of the bowel are

closed, the effused blood and other matters are removed, and in many

cases life has thus been preserved.

By increase of knowledge of the anatomy of the brain, and of the

distribution of nerves connected with it, it has become possible in a

certain number of cases to determine what part of the brain is suffering

from irritation or pressure, and to operate for the removal of the

tumour or other substance causing the trouble, with considerable hope of

giving permanent relief. A branch of surgery which has developed into an

important specialty during the last century is that known as plastic and

orthopædic surgery [ameliorating deformities]. The replacing of a lost

nose by engrafting other tissue in its place is a very old triumph of

surgical art, but operations of this kind have been greatly extended and

perfected within the last hundred years, and much can now be done to

mitigate the deformity and weakness due to club feet, bandy legs,

contracted joints, etc., which formerly were considered to be beyond

remedy.

Many of the diseases peculiar to women have been deprived of much of

their terrors within a hundred years. In 1800, for every thousand

children born, from ten to twenty mothers died. Puerperal fever occurred

in epidemics, following certain physicians and nurses, but nothing was

known as to its causes or nature. To-day puerperal fever is almost

unknown in the hospitals or in the practice of a skilled physician. The

death-rate of mothers is less than five per thousand births, and the

mechanical obstructions which a century ago would almost certainly have

brought about the death of both mother and child, are now so dealt with

that more than half of both mothers and children are saved.

The study of the diseases of the eye has greatly developed another

specialty during the century, viz., ophthalmology. The investigations of

Helmholtz in physiological optics, with his invention of the

ophthalmoscope in 1852, effected a revolution in this branch of medical

science and art, and have added greatly to human comfort and happiness.

A hundred years ago, when the physician saw the eyelids of a new-born

babe redden, and swell, and yellow matter ooze from between them, he

knew that in a few days or weeks the child would be partially or wholly

blind, but he knew nothing of the simple means by which the skilled

physician can now prevent such a calamity. It is unfortunately true that

this knowledge is not even now sufficiently widely diffused, and that

our blind asylums must, for some time to come, continue to receive those

that have been deprived of sight during the first months of their life

through the ignorance or neglect of those who should have properly cared

for them.

While it is certain that the death-rates in the last century were

greater than those of the present day, it is not possible to make

precise comparisons. The record of deaths in the city of New York

begins with 1804, and was necessarily very imperfect until the law of

1851, which required the registration of all deaths; but it shows a

death-rate of 30.2 per 1,000 in 1805, which means that the true

death-rate must have been between 35 and 40. At present, for a series of

five years, it would be about 20, having been below 19 in 1899, so that

the death-rate has been diminished by at least one-third. How much of

this is due to improved sanitary conditions it is impossible to say. A

comparison of the list of causes of death in 1805 with the list of

causes for 1900 shows great differences, but much of this is due to

changes in name and to more accurate diagnosis.

"Malignant sore throat" and "croup" were well known to anxious parents

in 1800, but "diphtheria" caused no anxiety. "Inflammation of the

bowels" was common and fatal, but "appendicitis" had not been heard of.

"Nervous fever," "continued fever," and "low fever" were on the lists,

but not typhoid, which was not clearly distinguished as a special form

of disease until 1837, when Dr. Gerhard, an American physician, pointed

out the differences between it and typhus, which also prevailed at the

commencement of the century.

One hundred years ago the great topic of discussion in our cities on the

North Atlantic coast was the means of preventing yellow fever, which had

been epidemic in New York and Philadelphia for two years. Physicians

were disputing as to whether the disease was contagious and imported,

and, therefore, perhaps, preventable by quarantine and disinfection, or

was due to some occult condition of the atmosphere (which was the view

taken by Noah Webster in his "History of Epidemic and Pestilential

Diseases," a work which appeared about the middle of the year 1800,

although it is dated 1789). The discussions remind one of the remark

that a certain patented form of electric light was surrounded by a cloud

of non-luminous verbosity. For example, the Committee of the Medical

Society of the State of New York reported that yellow fever may be

produced in any country by pestilential effluvia; and Webster concluded

that typhus and nervous fevers were due to a "conversion of the

perspirable fluids of the body into septic [poisonous] matter"--all of

which means that they knew nothing about it. Even now we do not know the

cause of yellow fever, or the precise mode of its spread; but we are

sufficiently certain that it is due to a specific micro-organism to be

confident that its spread can be checked by isolation and disinfection

properly applied--and Memphis and New Orleans are witnesses to the truth

of this.

In the year 1800, the majority of persons over twenty years old were

more or less pitted by small-pox, being the survivors of a much greater

number who had suffered from this disease. Dr. Miller in New York had

just received from England a thread which had been steeped in the newly

discovered vaccine matter, and was about to begin vaccination in this

city. To-day there are many physicians who have never seen a case of

small-pox, and a face pitted with the marks of this disease is rarely

seen.

During the century there have appeared in civilized countries two

strange and unfamiliar forms of epidemic disease, namely, Asiatic

cholera and the plague, the first coming from the valley of the Ganges,

the second from the valley of the Euphrates, and each having a long

history. A really new disease was the outbreak in Paris in 1892 of a

specific contagious disease transmitted from sick parrots, and known as

psittacosis. This little epidemic affected forty-nine persons, and

caused sixteen deaths. Typhus fever has almost disappeared, while some

diseases have increased in relative frequency, in part, at least,

because of medical progress. The children who would have died of

small-pox in the eighteenth century now live to be affected with

diphtheria or scarlet fever, and the increase in the number of deaths

reported as due to cancer is partly due to the fact that a greater

proportion of people live to the age most subject to this disease.

A large part of modern progress in medicine is due to improved methods

of diagnosis, and to the use of instruments of precision for recording

the results of examinations. The use of the clinical thermometer has

effected a revolution in medical practice. Our knowledge of diseases of

the heart and lungs has been greatly expanded during the century by

auscultation [trained listening to sounds] and percussion, and

especially by the use of the stethoscope. The test-tube and the

microscope warn us of kidney troubles which formerly would not have been

suspected, and the mysterious Röntgen rays are called in to aid the

surgeon in locating foreign bodies and in determining the precise nature

of certain injuries of the bones. Bacteriological examination has become

a necessary part of the examination in cases of suspected diphtheria,

tuberculosis, or typhoid, and a minute drop of blood under the

microscope may furnish data which will enable the skilled physician to

predict the result in certain cases of anæmia [bloodlessness], or to

make a positive diagnosis as between malaria and other obscure forms of

periodic fever.

The means at the command of the physician for the relief of pain now

include, not only the general anæsthetics,--chloroform, ether, and

nitrous oxide,--but also the hypodermic use of the concentrated

alkaloids of opium, belladonna, and other narcotics, and the local use

of cocaine; and restful sleep for the weary brain may be obtained by

sulphonal, chloral, etc. Some agonizing forms of neuralgic pain are now

promptly relieved by the section or excision of a portion of the

affected nerve; or it may be forcibly stretched into a condition of

innocuous desuetude. Relief to the sufferings of thousands of neurotic

women, and of their families and friends, has been produced by the

systematic scientific application of the rest cure of Dr. Weir Mitchell.

A hundred years ago the medical advertisement which was most prominent

in New York and Philadelphia newspapers was one of a remedy for worms.

Many symptoms of nervous and digestive troubles in children were in

those days wrongly attributed to worms. Nevertheless, there is good

reason to believe that parasitic diseases derived from animals were in

those days much more prevalent in this country than they are to-day. Our

knowledge of the mode of origin and development of the tapeworm, the

_trichina spiralis_, the liver fluke, and the itch insect has been

gained during the nineteenth century. Much the same may be said with

regard to the peculiar worm known as _anchylostum_, the cause of

Egyptian chlorosis, and of the St. Gothard tunnel disease, although

prescriptions for this parasite are found in the Papyrus Ebers, written

before the time of Pharaoh.

The limits of this article permit of but a brief reference to the

progress in preventive medicine during the century. The studies made in

England of the results of the cholera epidemic of 1849, and the

experience gained in the English army during the Crimean war, led to

some of the most important advances in sanitary science, more

especially to the demonstration of the importance of pure water

supplies, and of proper drainage and sewerage. During our Revolutionary

War, and the Napoleonic wars, the losses to the armies from disease

greatly exceeded those from wounds; and hospital fever--in other words,

typhus--was dreaded by a general almost more than the opposing forces.

During the wars of the last twenty-five years, typhus and hospital

gangrene have been unknown, but some extensive outbreaks of typhoid

fever have occurred, showing that our knowledge of the causes and mode

of transmission of this disease has not been practically applied to the

extent to which it should have been; this remark applies also to some of

the most fatal diseases in civil life. In the United States diphtheria

and typhoid fever each causes from twenty to thirty thousand deaths a

year, while more than one hundred thousand deaths are annually due to

consumption. Yet for each of these diseases we know the specific germ,

the channels through which it is usually conveyed, and the means by

which this conveyance can be to a great extent prevented. The ravages of

these diseases are, therefore, largely due to the fact that the great

mass of the people are still ignorant of these subjects. Antitoxin is

not yet used for either prevention or treatment in diphtheria to

anything like the extent which our knowledge of its powers demands.

Our better knowledge of the causes of certain infectious and contagious

diseases, and of the mode of their spread, has been of great importance

to the world from a purely commercial point of view, since it has led to

the doing away with many unnecessary obstructions to traffic and travel

which were connected with the old systems of quarantine, while the

security which has been gained from the modern method of cleansing and

disinfection is decidedly greater than that secured by the old methods.

A striking illustration of the effect of these improvements is seen in

the manner in which the news of the recent outbreak of plague in Glasgow

was received in England and throughout Europe. One hundred years ago the

city would have been almost deserted, and terror would have reigned in

all England. To-day it is well understood that the disease spreads by a

bacillus which is not conveyed through the air. No one fears a

repetition of the ghastly scenes of the Black Death in the fourteenth

century. In like manner, and for the same reasons, Asiatic cholera has

lost most of its terrors.

The benefits to the public of modern progress in medicine have been

greatly enlarged by the establishment of many small hospitals, and by

the steady increase in the employment of specially trained nurses in

private practice, even in rural districts. The results of a case of

typhoid or of pneumonia often depend as much upon the nurse as upon the

doctor; and affection cannot take the place of skill in either. For the

great mass of the people, cases of severe illness or injury, or those

requiring major surgical operations, can be treated more successfully in

well-appointed hospitals than in private houses, and as this is becoming

generally understood the old feeling against entering a hospital for

treatment is rapidly disappearing. Improvement in hospital construction

and management has kept pace with progress in medical knowledge; and in

future such institutions seem destined to play an increasingly important

part in municipal and village life.

All progress in civilization is attended with injury to some

individuals. Trained nurses have deprived some unskilled labour of

employment; hospitals have injured the business of some physicians;

pure-water supplies, good sewers, food inspection, vaccination,--in

short, all effective measures in public hygiene,--interfere with the

trade side of medical practice; but upon the whole the public at large

benefits by all these things. In one sense they seem opposed to the

general law of evolution, in that they prolong the life of the unfit;

but in a broader sense they work in accordance with this law by

increasing the power of the strong to protect and care for the weak.

All told, the most important feature in the progress of medicine during

the century has been the discovery of new methods of scientific

investigation, more especially in the fields of bacteriology and

pathology. These methods have been as yet only partially applied, and

great results are to be hoped from their extension in the near future.

They will not lead to the discovery of an elixir of life, and the

increasing feebleness of old age will continue to be the certain result

of living a long time, for the tissues and organs of each man have a

definitely limited term of duration peculiar to himself; but many of the

disorders which make life a burden in advancing years can now be

palliated, or so dealt with as to secure comparative comfort to the

patient, so that "if by reason of strength" life can be prolonged beyond

threescore years and ten it no longer necessarily involves labour and

sorrow.

Transcriber's Notes:

Punctuation and hyphenated and accented words have been standardized.

All else remains as in the original.

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